2,036 results match your criteria Testicle Trauma


Crossover transseptal vasovasostomy: alternative for very selected cases of iatrogenic injury to vas deferens.

Int Braz J Urol 2019 Jan 5;45. Epub 2019 Jan 5.

Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.

Inguinal herniorraphy is a possible cause of iatrogenic seminal tract obstruction. Diagnosing and correcting these vasal injuries can be challenging. Successful re-anastomosis is technically challenging, with relatively low success rates. Read More

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http://dx.doi.org/10.1590/S1677-5538.IBJU.2018.0445DOI Listing
January 2019

The dangers of hurling-genital injuries arising in the modern game.

Ir J Med Sci 2019 Jan 19. Epub 2019 Jan 19.

Department of Urology, University Hospital Waterford, Waterford, Ireland.

Objective: To assess the proportion of penoscrotal injuries arising from the sport of hurling and to assess work-up and management of each injury.

Methods: Using Hospital In-Patient Enquiry data, all penoscrotal injuries occurring over a 10-year period between 2007 and 2017 were identified and assessed. Chart review, imaging reports, operative notes and discharge summaries were used to identify the aetiology of each injury and those occurring due to hurling were selected for analysis. Read More

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http://dx.doi.org/10.1007/s11845-019-01969-xDOI Listing
January 2019
2 Reads

Testicular necrosis due to complicated epididymitis and ruptured sperm granuloma in a 13-year-old boy.

J Surg Case Rep 2019 Jan 4;2019(1):rjy349. Epub 2019 Jan 4.

Pediatric Surgery Department, Penteli Children's Hospital, Ippokratous 8, Penteli, Athens, Hellas, Greece.

Sperm cell granuloma, also termed epididymitis nodosa, is a form of chronic epididymitis that occurs secondary to inflammation, trauma, and/or a vasectomy. We present a rare such case that to our knowledge is unique in pediatric literature: a 13-year-old boy presented with clinical and sonographic findings of epididymo-orchitis. At first, the boy was admitted for a short course of conservative treatment and was discharged. Read More

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https://academic.oup.com/jscr/article/doi/10.1093/jscr/rjy34
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http://dx.doi.org/10.1093/jscr/rjy349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319168PMC
January 2019
4 Reads

Does low-level laser therapy on degenerated ovine testes improve post-thawed sperm characteristics?

Lasers Med Sci 2018 Nov 21. Epub 2018 Nov 21.

Laboratory of Teaching and Research in Pathology of the Reproduction - Center of Biotechnology in Animal Reproduction, Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga, SP, Brazil.

Low-level laser therapy (LLLT) can modulate redox state of the cell which could be useful to treat testicular degeneration and also prevent injuries by sperm cryopreservation. The aim of this study was to evaluate the effects of LLLT treatment on semen cryopreservation from rams submitted or not to testicular degeneration by testicular insulation. Eleven White Dorper rams were divided into four groups: animals that were not insulated (Control) and not treated (No Laser) (n = 2); animals that were not insulated and treated with LLLT (n = 3); animals that were insulated and not treated with LLLT (n = 3), and animals that were insulated and treated with LLLT (n = 3). Read More

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http://dx.doi.org/10.1007/s10103-018-2690-7DOI Listing
November 2018
9 Reads

Scrotal injuries during neonatal circumcision.

J Pediatr Urol 2018 Oct 18. Epub 2018 Oct 18.

Pediatric Urology, Dana-Dwek Children's Hospital, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University Tel-Aviv, Israel.

Objective: To report very rarely encountered scrotal injuries during neonatal circumcision. Hospitals and physicians in the authors' country are mandated to report circumcision complications to the Ministry of Health. Those reports include the discharge summary from the emergency room or the admitting department. Read More

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http://dx.doi.org/10.1016/j.jpurol.2018.10.009DOI Listing
October 2018
1 Read

The efficacy of chronic zinc oxide nanoparticles using on testicular damage in the streptozotocin-induced diabetic rat model.

Acta Histochem 2019 Jan 6;121(1):84-93. Epub 2018 Nov 6.

Anatomy & Embryology Department, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt.

Testicular impairment is a common complication of Diabetes mellitus (DM). Zinc Oxide Nanoparticles (ZnO NPs) are a novel agent for Zn delivery with antidiabetic and antioxidant activities. However, few reports were recorded on it. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00651281183026
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http://dx.doi.org/10.1016/j.acthis.2018.10.010DOI Listing
January 2019
7 Reads

Impaired spermatogenesis, tubular wall disruption, altered blood-testis barrier composition and intratubular lymphocytes in an infertile Beagle dog - a putative case of autoimmune orchitis.

Histol Histopathol 2018 Nov 7:18058. Epub 2018 Nov 7.

Institute for Anatomy, University of Veterinary Medicine Hannover, Hannover, Germany.

Impairment of blood-testis barrier integrity can be observed during inflammation, infection, trauma and experimental autoimmune orchitis, which is inducible in rodents. In the present study, an initially fertile two-year-old Beagle dog was presented with a decline in total sperm number resulting in azoospermia within five months, verified by twice-monthly semen analyses. The dog was clinically healthy with bilateral small testes and showed normal thyroid function. Read More

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http://www.hh.um.es/Abstracts/Vol_/_/__18058.htm
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http://dx.doi.org/10.14670/HH-18-058DOI Listing
November 2018
8 Reads

Single-Port Laparoscopic Assisted Transcrotal Orchidopexy for Palpable Inguinal Canalicular Cryptorchidism Accompany With Indirect Inguinal Hernia.

Front Pediatr 2018 9;6:293. Epub 2018 Oct 9.

Department of Pediatric Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China.

To assess the outcomes of a novel laparoscopic assisted transcrotal orchidopexy (LATO) combined with percutaneous extraperitoneal closure (PEC) for palpable inguinal canalicular cryptorchidism accompany with indirect inguinal hernia, and evaluate its safety and efficiency. A retrospective cohort study for single-port LATO-PEC and traditional inguinal orchidopexy (TIO) was performed between 2011 and 2014. Totally 53 children with both palpable inguinal canalicular testes and indirect inguinal hernia were included. Read More

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https://www.frontiersin.org/article/10.3389/fped.2018.00293/
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http://dx.doi.org/10.3389/fped.2018.00293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189310PMC
October 2018
9 Reads

Incompatibility assessment of Genkwa Flos and Glycyrrhizae Radix et Rhizoma with biochemical, histopathological and metabonomic approach.

J Ethnopharmacol 2019 Jan 17;229:222-232. Epub 2018 Oct 17.

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, and Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:

Ethnopharmacological Relevance: As recorded in traditional Chinese medicine (TCM) theory, Genkwa Flos (YH) and Glycyrrhizae Radix et Rhizoma (GC) compose one herbal pair of the so-called "eighteen incompatible medicaments", which indicate pairs of herbs that are mutually incompatible and that theoretically should not be applied simultaneously. However, the theory has been called into question due to a lack of evidence.

Aims Of Study: In this study, the incompatibility of YH and GC was investigated based on an assessment of the toxic effects of their combination by traditional safety methods and a modern metabonomic approach. Read More

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http://dx.doi.org/10.1016/j.jep.2018.10.014DOI Listing
January 2019
11 Reads

Cerebrospinal fluid hydrocele caused by scrotal migration of a ventriculoperitoneal shunt.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Radiology, Aga Khan University, Karachi, Sindh, Pakistan.

A 6-month-old boy presented with painless right hemiscrotal swelling. The scrotal ultrasound revealed a cerebrospinal fluid hydrocele caused by the migration of a ventriculoperitoneal shunt (VPS) catheter tip into the right hemiscrotum and associated undescended left testis. Earlier, he underwent a VPS placement for hydrocephalus secondary to neonatal bacterial meningitis and ventriculitis. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22469
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http://dx.doi.org/10.1136/bcr-2018-224698DOI Listing
October 2018
14 Reads

Acute testicular pain secondary to a leaking abdominal aortic aneurysm (AAA).

BMJ Case Rep 2018 Sep 19;2018. Epub 2018 Sep 19.

Intensive Care Unit, Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, West Yorkshire, UK.

We present the case of a 56-year-old male smoker with a background of hypertension who presented with acute onset right testicular pain secondary to a leaking abdominal aortic aneurysm. Following urgent surgical repair and a complicated intensive care recovery, the patient was discharged with no residual disability. This case highlights an atypical presentation of what is a devastating illness. Read More

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http://dx.doi.org/10.1136/bcr-2018-226577DOI Listing
September 2018
1 Read

Genitalia self-mutilation commanded by hallucinations: a psychointensive case of Klingsor syndrome.

BMJ Case Rep 2018 Sep 18;2018. Epub 2018 Sep 18.

Department of Surgery, Narayana Medical College and Hospital, Nellore, India.

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http://dx.doi.org/10.1136/bcr-2018-226838DOI Listing
September 2018
2 Reads

Single and combined exposure of microcystin-LR and nitrite results in reproductive endocrine disruption via hypothalamic-pituitary-gonadal-liver axis.

Chemosphere 2018 Nov 13;211:1137-1146. Epub 2018 Aug 13.

College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, PR China.

Microcystin-LR (MC-LR) released by Microcystis blooms degradation usually co-exists with a chemical called nitrite, posing a serious harm to aquatic organisms. To assess the single and combined effects of MC-LR and nitrite on the reproductive endocrine system, a fully factorial experiment was designed and adult male zebrafish (Danio rerio) were exposed to 9 treatment combinations of MC-LR (0, 3, 30 μg/L) and nitrite (0, 2, 20 mg/L) for 30 d. The results showed that both MC-LR and nitrite caused concentration-dependent effects including the growth inhibition, decreased gonad index as well as testicular injuries with widen intercellular spaces and seminiferous epithelium deteriorations. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2018.08.049DOI Listing
November 2018
4 Reads
3.340 Impact Factor

[Micro-dissection testicular sperm extraction for non-obstructive azoospermia patients with the history of secondary testicular injury].

Zhonghua Nan Ke Xue 2018 08;24(8):681-685

Center of Reproduction, The Sixth Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510620, China.

Objective: To investigate the value of micro- dissection testicular sperm extraction (micro-TESE) in the treatment of non-obstructive azoospermia (NOA) in patients with the history of secondary testicular injury.

Methods: Totally, 121 NOA patients with the history of secondary testicular injury underwent micro-TESE in our hospital from September 2014 to December 2017. We analyzed the correlation of the sperm retrieval rate with the causes of testicular injury and compared the outcomes of the ICSI cycles with the sperm retrieved from the NOA males by micro-TESE (the micro-TESE group) and those with the sperm ejaculated from severe oligospermia patients (sperm concentration <1×10⁶/ml, the ejaculate group). Read More

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August 2018
35 Reads

Reversible effects of anabolic steroid abuse on cyto-architectures of the heart, kidneys and testis in adult male mice.

Biomed Pharmacother 2018 Oct 12;106:917-922. Epub 2018 Jul 12.

Laboratory of Natural Bioresources, Faculty of Science, Department of Biology, University of Hassiba Ben Bouali, BP 151, 02000, Chlef, Algeria.

The importance of the present study comes from the lack of sufficient information about the reversibility of the histopathological alterations which may result from anabolic androgenic drugs abuse after some times of stop treatment, as it is one of the prior studies which explored the negative effects of Deca-Durabolin abuse in particular on the hearts, kidneys and testis structures. For this aim, study was performed on 40 male adult mices. Animals were divided into five groups of 8 animals each as follows: treated by Deca-Durabolin (nandrolone decanoate) at 30 g/kg of BW, weekly during one month (GI); two months (GII); three months (GIII); three months followed by six weeks of treatment discontinuation (GIV) and Control (C). Read More

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http://dx.doi.org/10.1016/j.biopha.2018.07.038DOI Listing
October 2018
5 Reads

CBLB502, a Toll-like receptor 5 agonist, offers protection against radiation-induced male reproductive system damage in mice.

Biol Reprod 2019 Jan;100(1):281-291

Department of Experimental Hematology and Biochemistry, Beijing Institute of Radiation Medicine, Beijing, China.

CBLB502, a Toll-like receptor (TLR)5 agonist derived from Salmonella flagellin, was shown to protect mammalian hematopoietic and gastrointestinal systems from acute irradiation syndrome and to stimulate regeneration. To explore whether CBLB502 can improve testicular injuries caused by irradiation, mice were intraperitoneally injected with 0.2 mg/kg CBLB502 or vehicle control 30 min prior to applying 5. Read More

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http://dx.doi.org/10.1093/biolre/ioy173DOI Listing
January 2019
7 Reads

Mechanism mediating the protective effect of diacerein in ischemia-reperfusion-induced testicular injury in rats.

Life Sci 2018 Sep 1;209:57-62. Epub 2018 Aug 1.

Department of Pharmacology, Faculty of Medicine, Minia University, 61511 Minia, Egypt.

Aims: Torsion of the spermatic cord is a common urologic emergency and can lead to testicular necrosis and infertility. Diacerein (DIA) is interleukin-1b (IL-1b) blocker which has a protective role against myocardial ischemia-reperfusion, however, to-date this role has not been investigated in testicular ischemia- reperfusion (TIR). We aimed to investigate the role and mechanism of action of DIA in induced TIR. Read More

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http://dx.doi.org/10.1016/j.lfs.2018.07.060DOI Listing
September 2018
10 Reads

The protective effects of Arctium lappa L. Extract on testicular injuries induced by ethanol in rats.

Andrologia 2018 Nov 13;50(9):e13086. Epub 2018 Jul 13.

Department of Biology, Faculty of Science, Bu-Ali Sina University, Hamedan, Iran.

The aim of this study is to assess the antioxidant activity and also protective effects of Arctium lappa L. (AL) extract on ethanol-induced testicular injuries in rats. In addition, the total phenol and flavonoid contents of the methanolic extracts were analysed and the antioxidant activity of the extract was investigated. Read More

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http://dx.doi.org/10.1111/and.13086DOI Listing
November 2018
1 Read
1.172 Impact Factor

Mechanisms of diazinon effects on impaired spermatogenesis and male infertility.

Toxicol Ind Health 2018 Sep 11;34(9):653-664. Epub 2018 Jul 11.

1 Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Diazinon (DZN) is an organophosphate insecticide that has cytotoxic and pathological effects on the reproductive system. It causes a wide variety of pathological effects on the reproductive system such as testicular atrophy, disturbance in sex hormones, impaired spermatogenesis, low quality of sperm, and fertility problems. However, molecular and cellular mechanisms of its adverse effects are not well understood. Read More

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http://dx.doi.org/10.1177/0748233718778665DOI Listing
September 2018
7 Reads

Fluorochloridone perturbs blood-testis barrier/Sertoli cell barrier function through Arp3-mediated F-actin disruption.

Toxicol Lett 2018 Oct 5;295:277-287. Epub 2018 Jul 5.

School of Public Health, MOE Key Laboratory for Public Health Safety, Key Laboratory of Health Technology Assessment of National Health Commission, Fudan University, Shanghai 200032, China. Electronic address:

There are reports of fluorochloridone (FLC)-induced male reproductive toxicity, but the underlying toxicological mechanisms remain unknown. In this study, we looked at how FLC exposure affected the integrity of the blood-testis barrier (BTB) and the Sertoli cell barrier and studied the molecular mechanisms. Male rats received gavage administration of FLC (30 mg/kg/d) for 14 consecutive days with sample collection at the 7th and 14th day; and primary cultured Sertoli cells were treated with 0-10 μM FLC in vitro for 24 h. Read More

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http://dx.doi.org/10.1016/j.toxlet.2018.07.001DOI Listing
October 2018
18 Reads

Comparative Profiling of MicroRNAs Reveals the Underlying Toxicological Mechanism in Mice Testis Following Carbon Ion Radiation.

Dose Response 2018 Apr-Jun;16(2):1559325818778633. Epub 2018 Jun 20.

College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.

This study investigated the toxicity of heavy ion radiation to mice testis by microRNA (miRNA) sequencing and bioinformatics analyses. Testicular indices and histology were measured following enterocoelia irradiation with a 2 Gy carbon ion beam, with the testes exhibiting the most serious injuries at 4 weeks after carbon ion radiation (CIR) exposure. Illumina sequencing technology was used to sequence small RNA libraries of the control and irradiated groups at 4 weeks after CIR. Read More

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http://dx.doi.org/10.1177/1559325818778633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024298PMC
June 2018
10 Reads

A novel experience of deferential vessel-sparing microsurgical vasoepididymostomy.

Asian J Androl 2018 Nov-Dec;20(6):576-580

Department of Urology and Andrology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510000, China.

Microsurgical longitudinal intussusception vasoepididymostomy (LIVE) has been widely used to treat epididymal obstructive azoospermia since 2004. Although the deferential vasculature plays an important role in supplying blood to the testis and epididymis, little attention has been paid to the potential benefits of sparing the deferential vessels during the anastomosis in LIVE. This study aimed to evaluate the efficacy and safety of deferential vessel-sparing LIVE in humans. Read More

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http://dx.doi.org/10.4103/aja.aja_46_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219301PMC
July 2018
17 Reads
2.530 Impact Factor

Genitourinary Surgical Workload at Deployed U.S. Facilities in Iraq and Afghanistan, 2002-2016.

Mil Med 2019 Jan;184(1-2):e179-e185

San Antonio Military Medical Center, Urology Clinic, 3551 Roger Brooke Drive, Ft. Sam Houston, TX.

Introduction: Genitourinary surgery constitutes approximately 1.15% of procedures performed for combat injuries. During forward deployment, surgeons usually deploy without urology support. Read More

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http://dx.doi.org/10.1093/milmed/usy152DOI Listing
January 2019
2 Reads

Lycopene abrogates di-(2-ethylhexyl) phthalate induced testicular injury by modulating oxidative, endocrine and inflammatory changes in mice.

Life Sci 2018 Aug 7;207:265-271. Epub 2018 Jun 7.

Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Physiology and Pharmacology, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Electronic address:

Di (2-ethylhexyl) phthalate (DEHP) is one of the environmental pollutants that causes testicular damage. Lycopene (LYCO), the main active carotenoid in red fruits and vegetables, has well-known antiinflammatory and antioxidant activities. The present study aimed to investigate the effects of LYCO on DEHP-induced testicular injury in male mice. Read More

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http://dx.doi.org/10.1016/j.lfs.2018.06.009DOI Listing
August 2018
81 Reads
2.702 Impact Factor

MALAT1 Promotes Cell Apoptosis and Suppresses Cell Proliferation in Testicular Ischemia-Reperfusion Injury by Sponging MiR-214 to Modulate TRPV4 Expression.

Cell Physiol Biochem 2018 29;46(2):802-814. Epub 2018 Mar 29.

Department of Urology, Renmin Hospital of Wuhan University, Wuhan, China.

Background/aims: Accumulating evidences has indicated that aberrant expression of long non-coding RNAs (lncRNAs) is tightly associated with the progression of ischemia-reperfusion injury (IRI). Previous studies have reported that lncRNA MALAT1 regulates cell apoptosis and proliferation in myocardial and cerebral IRI. However, the underlying mechanism of MALAT1 in testicular IRI has not been elucidated. Read More

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http://dx.doi.org/10.1159/000488738DOI Listing
July 2018
7 Reads

The protective effects of alpha lipoic acid on methotrexate induced testis injury in rats.

Biomed Pharmacother 2018 Jan 20;97:1486-1492. Epub 2017 Nov 20.

Department of Medical Pharmacology, School of Medicine, Cukurova University, Adana, Turkey.

Methotrexate (MTX) is frequently used in the treatment of several diseases including cancers, rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, and dermatomyositis. Previously, chemotherapeutic agents have been reported to cause permanent azoospermia and infertility in men. Methotrexate has been also shown to damage the seminiferous tubules of the testicles, lower the sperm count, and cause genetic mutations (in DNA) in sperm. Read More

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http://dx.doi.org/10.1016/j.biopha.2017.11.078DOI Listing
January 2018
4 Reads

Effects of Intratesticular Hematoma on Testis Microstructure, Spermatogenesis, and Testosterone Production: Defining a Cutoff Point for Significant Intratesticular Hematoma.

Urology 2018 Aug 16;118:80-86. Epub 2018 May 16.

Department of Urology, Shiraz University of Medical Sciences, Shiraz, Iran.

Objective: To evaluate the effects of different degrees of intratesticular hematoma (ITH), a major consequence of blunt testis trauma, on testis microstructure and function. We determined a cutoff point for significant vs nonsignificant ITH.

Methods: Seventy male rats were divided into 7 equal groups. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00904295183046
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http://dx.doi.org/10.1016/j.urology.2018.05.005DOI Listing
August 2018
64 Reads
2.190 Impact Factor

The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.

Poult Sci 2018 Sep;97(9):3248-3257

College of Wildlife Resources, Northeast Forestry University, Harbin 150040, Heilongjiang Province, China.

The aim of this study is to investigate whether arsenic (As) could induce testicular poisoning and influence the oxidative stress, apoptosis and autophagy in chickens. Seventy-two 1-day-old male Hy-line chickens were divided into 4 groups which were exposed to 0, 0.625, 1. Read More

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http://dx.doi.org/10.3382/ps/pey156DOI Listing
September 2018
8 Reads

[Dynamic changes of pH2AX expression in the reversibility of mouse testicular reproductive function impaired by single heat stress].

Zhonghua Nan Ke Xue 2017 Oct;23(10):873-877

Department of Reproductive Medicine, The Affiliated Hospital of Binzhou Medical College, Binzhou, Shandong 256600, China.

Objective: To investigate the role of pH2AX in the reversibility of mouse testicular reproductive function impaired by single heat stress.

Methods: Twenty-four C57 male mice were randomly divided into heat stress and control groups and immersed in water at 43℃ and 25℃, respectively, for 15 minutes. At 1, 7, and 14 days of heat exposure, all the mice were sacrificed and their testis tissues collected for determining the apoptosis of the germ cells by TUNEL and measuring the expression level of the pH2AX protein by immunohistochemistry and Western blot. Read More

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October 2017
4 Reads

[Single scrotal-incision orchidopexy without ligation of processus vaginalis for palpable undescended testis].

Zhonghua Nan Ke Xue 2017 Aug;23(8):708-712

Department of Pediatric Surgery, Ningbo Women and Children's Hospital, Ningbo, Zhejiang 315012, China.

Objective: To determine the feasibility and short-term effect of single scrotal-incision orchidopexy (SSIO) without ligation of the processus vaginalis (PV) in the treatment of palpable undescended testis (PUDT).

Methods: This retrospective study included 109 cases of PUDT (125 sides) and 15 cases of impalpable undescended testis (IUDT). The former underwent SSIO without PV ligation (group A, n = 53) or standard inguinal orchidopexy with PV ligation (group B, n = 56) while the latter received laparoscopic exploration (group C). Read More

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August 2017
7 Reads

Necropsy findings of koalas from the Mount Lofty Ranges population in South Australia.

Aust Vet J 2018 May;96(5):188-192

School of Animal and Veterinary Sciences, Faculty of Sciences, University of Adelaide, Roseworthy campus, Roseworthy, South, Australia 5371, Australia.

Objective: This study reports necropsy findings of koalas from the Mount Lofty Ranges region in order to identify health threats to this mainland South Australian population.

Methods: Koalas from the Mount Lofty Ranges region (n = 85) that had died or been euthanased on welfare grounds were examined at necropsy during 2012-13 at the School of Animal and Veterinary Sciences, University of Adelaide. Disease findings, approximate age, sex and body condition of koalas were recorded. Read More

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http://dx.doi.org/10.1111/avj.12690DOI Listing
May 2018
2 Reads

Cadmium inhibits lysine acetylation and succinylation inducing testicular injury of mouse during development.

Toxicol Lett 2018 Jul 10;291:112-120. Epub 2018 Apr 10.

Shanghai Key Lab of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

The toxic effects of cadmium (Cd) in the reproductive system have been confirmed, and lysine acetylation and succinylation play important roles in spermatogenesis. However, little attention determined whether Cd could affect lysine acylation and how it might have an impact on the reproductive system. Therefore, with the goal of contributing to this subject, we have examined the effects of Cd on lysine acetylation and succinylation of proteins in the germ cells of male mice testes during different developmental stages. Read More

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http://dx.doi.org/10.1016/j.toxlet.2018.04.005DOI Listing
July 2018
14 Reads

British Association of Urological Surgeons (BAUS) consensus document for the management of male genital emergencies - testicular trauma.

BJU Int 2018 06 10;121(6):840-844. Epub 2018 Apr 10.

Department of Urology and NIHR Biomedical Research Centre, University College London Hospital, London, UK.

Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-site expertise in genitourethral surgery. A series of consensus statements have been developed by an expert consensus comprising British Association of Urological Surgeons (BAUS) Section of Andrology and Genitourethral Surgery together with experts from units throughout the UK. Read More

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http://dx.doi.org/10.1111/bju.14163DOI Listing
June 2018
4 Reads

Testicular atrophy following inguinal hernia repair in children.

Pediatr Surg Int 2018 May 28;34(5):553-560. Epub 2018 Mar 28.

Department of Surgery, Boston Children's Hospital, Boston, MA, USA.

Purpose: We sought to determine the incidence and timing of testicular atrophy following inguinal hernia repair in children.

Methods: We used the TRICARE database, which tracks care delivered to active and retired members of the US Armed Forces and their dependents, including > 3 million children. We abstracted data on male children < 12 years who underwent inguinal hernia repair (2005-2014). Read More

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http://link.springer.com/10.1007/s00383-018-4255-z
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http://dx.doi.org/10.1007/s00383-018-4255-zDOI Listing
May 2018
23 Reads

CTRP3 attenuates high-fat diet-induced male reproductive dysfunction in mice.

Clin Sci (Lond) 2018 Apr 30;132(8):883-899. Epub 2018 Apr 30.

Reproductive Medicine Center, Renmin Hospital of Wuhan University, Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan 430060, China

Recent studies have suggested a role for abdominal obesity in male infertility. Previous studies have found that cell apoptosis exerts an important role in obesity-related male infertility. C1q/TNF-related protein 3 (CTRP3), a paralog of adiponectin, has been proposed to exert anti-apoptotic effects and to attenuate diabetes-related cardiac injuries. Read More

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http://dx.doi.org/10.1042/CS20180179DOI Listing
April 2018
3 Reads

A Survey of the Current Practice Patterns of Contralateral Testis Fixation in Unilateral Testicular Conditions.

Urology 2018 Jun 20;116:156-160. Epub 2018 Mar 20.

The Department of Urology of the University of California, Irvine and Children's Hospital of Orange County, Orange, CA.

Objective: To query the current contralateral testis fixation (CTF) practice patterns among pediatric urologists in different clinical situations that could result in monorchism.

Methods: An online survey was sent to members of the Urology Section of the American Academy of Pediatrics. The survey included questions addressing CTF practice patterns in 14 clinical scenarios. Read More

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http://dx.doi.org/10.1016/j.urology.2018.03.008DOI Listing
June 2018
12 Reads

Rosemary extract modulates fertility potential, DNA fragmentation, injury, KI67 and P53 alterations induced by etoposide in rat testes.

Biomed Pharmacother 2018 Feb 4;98:769-774. Epub 2018 Jan 4.

Zoology Department, Faculty of Science, Menoufiya University, Egypt.

Etoposide is a semi-synthetic compound derived from the plant podophyllum pelltatum and are antineoplastic agents long been used for treatment of human malignancies. The present study was conducted to examine the possible modifying effects of rosemary aqueous extract against sperm abnormalities, testes injury, DNA fragmentation, apoptosis and Ki67 alterations induced by Etoposide in male rats. A total of 50 adult male rats were divided into 5 groups (1st, control; 2nd, rosemary; 3rd, Etoposide; 4th, co-treated Etoposide with rosemary; 5th, post-treated Etoposide with rosemary). Read More

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http://dx.doi.org/10.1016/j.biopha.2018.01.025DOI Listing
February 2018
2 Reads

In utero heat stress causes reduced testicular area at puberty, reduced total sperm production, and increased sperm abnormalities in boars.

Anim Reprod Sci 2018 May 24;192:126-135. Epub 2018 Feb 24.

Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, United States. Electronic address:

In utero stress has been shown to negatively affect intact male rats and mice, though very little research has been conducted in boars. The objectives of the present studies were to determine the effects of in utero heat stress (IUHS) on postnatal development and the response to postnatal heat stress of boars. Ten boars were selected at weaning from litters subjected to IUHS or in utero thermoneutral (IUTN) during 30-60 days of gestation. Read More

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http://dx.doi.org/10.1016/j.anireprosci.2018.02.022DOI Listing
May 2018
2 Reads

A new model for chronic diseases.

Authors:
S D Sara Diani

Med Hypotheses 2018 Apr 15;113:30-39. Epub 2018 Feb 15.

Independent Researcher, Mantova, Italy. Electronic address:

Chronic diseases are defined diseases whose symptoms last for at least six months and tend to worsen over time. In Europe, they cause at least 86% of deaths. In this speculative unifying model I set a new hypothesis for the etiology of the majority of chronic diseases. Read More

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http://dx.doi.org/10.1016/j.mehy.2018.02.011DOI Listing
April 2018
3 Reads

Blunt scrotal trauma in adults: A multi-institution study evaluating the American Association for the Surgery of Trauma organ injury grading scale About 107 cases.

Tunis Med 2017 May;95(5):331-335

Purpose: The authors evaluated the usefulness of the American Association for the Surgery of Trauma (AAST) testis injury scale based on preoperative scrotal ultrasonography (US) and physical examination compared to peroperative findings.

Methods: A retrospective review was performed on 107 patients (mean age=29,2±5.8 years) with a testis blunt trauma treated between January 2005 and August 2015. Read More

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May 2017
6 Reads

Cilostazol alleviates streptozotocin-induced testicular injury in rats via PI3K/Akt pathway.

Life Sci 2018 Apr 27;198:136-142. Epub 2018 Feb 27.

Department of Histology, Faculty of Medicine, Minia University, 61511 Minia, Egypt.

Aims: Male infertility prevalence is higher in diabetic patients. Those patients exhibit testicular oxidative damage due to sustained hyperglycemia and inflammation. The study has investigated the efficacy of cilostazol, a phosphodiesterase 3 inhibitor, on testicular damage of diabetic rats. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00243205183009
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http://dx.doi.org/10.1016/j.lfs.2018.02.038DOI Listing
April 2018
25 Reads

Imaging of the scrotum: beyond sonography.

Insights Imaging 2018 Apr 15;9(2):137-148. Epub 2018 Feb 15.

Department of Morphology, Surgery and Experimental Medicine, Section of Radiology, University of Ferrara, Via Ludovico Ariosto 35, 44121, Ferrara, Italy.

The aim of this article is to describe the role of second-level imaging techniques after an initial ultrasonography evaluation in the assessment of scrotal diseases. While ultrasonography remains central as the primary imaging modality for the evaluation of pathologic conditions of the scrotum, the role of magnetic resonance imaging continues to evolve: it can actually be valuable as a problem-solving tool when sonographic findings are equivocal or inconclusive. Magnetic resonance imaging of the scrotum may provide accurate detection and characterization of scrotal diseases, well depicting the precise location of scrotal masses (intratesticular or extratesticular) and reliably characterizing benign conditions simulating neoplastic processes, thus preventing unnecessary radical surgery. Read More

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http://dx.doi.org/10.1007/s13244-017-0592-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893488PMC
April 2018
4 Reads

Improving Sperm Viability After Spinal Cord Injury Using Hyperbaric Therapy.

World Neurosurg 2018 May 9;113:e232-e238. Epub 2018 Feb 9.

Department of Neurosurgery, University of Caxias do Sul, Caxias do Sul, Rio Grande do Sul, Brazil.

Background: Infertility is one of many complications of spinal cord injury (SCI) in male patients, who are often at the peak of their reproductive life. This study evaluated effects of hyperbaric therapy (HT) on quality of sperm of rats with SCI and correlated the findings with histologic analysis of the testicles.

Methods: This experimental study comprised 18 rats that were submitted to SCI with a MASCIS Impactor and randomly allocated to either a HT or a control group. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.01.216DOI Listing
May 2018
7 Reads

Probiotics as a Complementary Therapy in the Model of Cadmium Chloride Toxicity: Crosstalk of β-Catenin, BDNF, and StAR Signaling Pathways.

Biol Trace Elem Res 2018 Oct 9;185(2):404-413. Epub 2018 Feb 9.

Molecular Biology, Therapeutic Chemistry Department, National Research Centre, Cairo, Egypt.

Cadmium chloride (CdCl) is a ubiquitous environmental toxicant that causes a variety of disturbances in biological systems, including brain dysfunction and testicular tissue degeneration. On the other hand, it is supposed that beneficial properties of probiotic bacteria (Lactobacillus and Acidobacillus) are related to their capacity to adhere or bind different targets, thus leading to improved intestinal microbial balance and other benefits to the host. Bearing aforementioned in mind, the present study was undertaken to investigate the protective effect of probiotic supplementation against cadmium chloride-induced brain and testis toxicity in mice model. Read More

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http://dx.doi.org/10.1007/s12011-018-1261-xDOI Listing
October 2018
8 Reads

Blunt testicular trauma - is surgical exploration necessary?

Ir J Med Sci 2018 Nov 8;187(4):1109-1113. Epub 2018 Feb 8.

Department of Urology, University Hospital Limerick, Limerick, Ireland.

Objectives: EAU and AUA guidelines recommend urgent surgical exploration in cases of suspected testicular rupture. However, the management of rupture to other encapsulated organs (e.g. Read More

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http://dx.doi.org/10.1007/s11845-017-1724-7DOI Listing
November 2018
1 Read

Suppurative appendicitis presenting acute scrotal pain: a rare condition may confuse surgeons.

J Surg Case Rep 2017 Oct 27;2017(10):rjx215. Epub 2017 Oct 27.

Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Scrotal pain presentation has many differential diagnoses such as testicular torsion is surgical emergency. For this reason, it is necessary for surgeons to differentiate between diseases for choosing the best treatment approach. We have reported a rare condition of 19-year-old male case had an atypical scrotal pain presentation of appendicitis. Read More

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http://dx.doi.org/10.1093/jscr/rjx215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798034PMC
October 2017
2 Reads

Chrysin Administration Protects against Oxidative Damage in Varicocele-Induced Adult Rats.

Oxid Med Cell Longev 2017 19;2017:2172981. Epub 2017 Dec 19.

Department of Morphology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, Brazil.

Oxidative stress is known as the leading factor responsible for varicocele-related infertility and for that reason, many antioxidant therapies have been proposed. Considering that, we evaluated the reproductive outcomes and fertility of varicocelized rats and the impact of chrysin within these parameters. The animals were allocated into three groups: sham (control), varicocele treated via gavage with 50 mg/kg/day of chrysin (V1), or vehicle (V2) for 56 days. Read More

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http://dx.doi.org/10.1155/2017/2172981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749274PMC
August 2018
9 Reads

The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy.

Biochim Biophys Acta Rev Cancer 2018 Apr 14;1869(2):189-199. Epub 2018 Feb 14.

CIAFEL - Research Centre in Physical Activity, Health and Leisure, Portugal; LAMETEX - Laboratory of Exercise and Metabolism; Faculty of Sport, University of Porto, Portugal.

Doxorubicin (DOX) is a widely used antineoplastic agent for a wide range of cancers, including hematological malignancies, soft tissue sarcomas and solid tumors. However, DOX exhibits a dose-related toxicity that results in life-threatening cardiomyopathy. In addition to the heart, there is evidence that DOX toxicity extends to other organs. Read More

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http://dx.doi.org/10.1016/j.bbcan.2018.01.002DOI Listing
April 2018
1 Read

Usefulness of Preoperative Ultrasound for the Evaluation of Testicular Rupture in the Setting of Scrotal Gunshot Wounds.

J Urol 2018 Jun 31;199(6):1546-1551. Epub 2018 Jan 31.

Division of Urology, John H. Stroger Jr. Hospital of Cook County, Chicago, Illinois.

Purpose: A scrotal gunshot wound may result in testicular injury, necessitating urgent scrotal exploration and attempted testicular salvage. Scrotal ultrasound is highly sensitive and specific for testicular rupture in the setting of blunt scrotal trauma but it has been poorly studied in the setting of scrotal gunshot wounds. Our objective was to determine the accuracy of scrotal ultrasound to identify testicular rupture following a scrotal gunshot wound. Read More

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http://dx.doi.org/10.1016/j.juro.2018.01.076DOI Listing
June 2018
2 Reads

Malignant Mesothelioma of Tunica Vaginalis Testis: Macroscopic and Microscopic Features of a Very Rare Malignancy.

Cureus 2017 Nov 19;9(11):e1860. Epub 2017 Nov 19.

Pathology, Trakya University Medical Faculty.

Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is an extremely rare tumour, usually mimicking benign pathologies of the scrotum. Our case is an 84-year-old male patient who appealed with a painless, left-sided scrotal swelling longer than 2 months. Although the level of tumour markers was normal, ultrasonographic examination results forced us to perform an inguinal scrotal exploration. Read More

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https://www.cureus.com/articles/9565-malignant-mesothelioma-
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http://dx.doi.org/10.7759/cureus.1860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773272PMC
November 2017
12 Reads