25,520 results match your criteria Teratomas and Other Germ Cell Tumors of the Mediastinum
Int J Surg Case Rep 2018 Nov 22;54:47-50. Epub 2018 Nov 22.
Department of General Surgery, King Abdulla University Hospital, Faculty of Medicine, Jordan University of Science and Technology, P.O. Box (3030), Irbid, 22110, Jordan. Electronic address:
Introduction: Sacrococcygealteratoma is very rare in adults with only few cases reported in literature. It is a slow growing benign cystic tumor with 1-2% chance for malignant transformation and may attain a huge size causing pressure effect on pelvic and intra-abdominal organs. When grows caudally, it causes discomfort, skin excoriation and cosmetic disfigurement. Read More
World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.
Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, HNS&FDRc, University of Insubria, Varese, Italy.
Background: Endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared to traditional open approaches, the endoscopic endonasal approach (EEA) presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.
Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of two rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More
Am J Ophthalmol Case Rep 2019 Mar 8;13:20-21. Epub 2018 Nov 8.
Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.
World J Nucl Med 2018 Oct-Dec;17(4):249-252
Hospital de Base do Distrito Federal - Nuclear Medicine Service, Brasília, Brasil.
The aim of this study was to assess the colonic transit in children and teenagers with chronic constipation. Twenty patients from 1.5 to 16 years old were included (mean age = 6. Read More
Stem Cell Reports 2018 Nov 27. Epub 2018 Nov 27.
Department of Pathology, Laboratory for Experimental Patho-Oncology, Erasmus MC Cancer Institute, Be-432A, PO Box 2040, 3000 CA Rotterdam, the Netherlands. Electronic address:
Predicting developmental potency and risk of posttransplantation tumor formation by human pluripotent stem cells (hPSCs) and their derivatives largely rely on classical histological analysis of teratomas. Here, we investigated whether an assay based on microRNAs (miRNA) in blood plasma is able to detect potentially malignant elements. Several hPSCs and human malignant germ cell tumor (hGCT) lines were investigated in vitro and in vivo after mouse xenografting. Read More
Pathology 2018 Nov 27. Epub 2018 Nov 27.
Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Hong Kong. Electronic address:
Malignant transformation of benign mature ovarian teratoma can result in a wide spectrum of cancer, including a variety of carcinoma, sarcoma, or melanoma. The role of mismatch repair defects in such malignant transformation is still elusive. In view of current immunotherapy, the role of mismatch repair deficiency can have significant implications on therapeutic strategy. Read More
Int J Gynecol Pathol 2018 Dec 3. Epub 2018 Dec 3.
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Primary extrarenal Wilms tumor of the gynecologic tract is extremely rare with scattered case reports occurring in the ovary, uterine corpus and cervix. Only 9 cases of primary ovarian Wilms tumor have been reported to date. Here, we provide an extensive literature review and describe 2 patients with ovarian Wilms tumor: a 36-yr-old female (patient 1) and a 16-yr-old female (patient 2), both presenting with abdominal pain and suspected ovarian torsion. Read More
Ann Plast Surg 2018 Dec 3. Epub 2018 Dec 3.
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center.
The pigment melanin is produced by melanocytes, is primarily responsible for skin color, and protects it against ultraviolet rays that can cause the destruction of genetic material within the keratinocytes. To elucidate the mechanisms of many diseases associated with melanocytes, such as melanoma and albinism, or burns with uneven pigment distribution, the disease model needs to be established first. In this study, we aimed to construct the melanocyte model from patients in a short period. Read More
J Surg Case Rep 2018 Nov 30;2018(11):rjy322. Epub 2018 Nov 30.
Department of Surgery, Harvard Medical School, The Cambridge Hospital, Cambridge, MA, USA.
A 26-year-old, otherwise healthy female presented to the Emergency Room for the evaluation of abdominal pain. It was immediately apparent that she had a massively distended abdomen. History revealed progressive abdominal distension over several years. Read More
BMC Pediatr 2018 Dec 4;18(1):382. Epub 2018 Dec 4.
Department of Respiratory Medicine, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Nanlishi Road 56, Xicheng District, Beijing, People's Republic of China.
Background: Mediastinal teratoma is uncommon in children. It can be very difficult to diagnose especially in early stage. Rarely, teratoma may rupture into adjacent structures and lead to lung lesions or pleuritis. Read More
Cardiovasc Pathol 2018 Oct 29;39:1-4. Epub 2018 Oct 29.
Cardiothoracic Surgery Department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental Carnaxide, Portugal.
Adv Exp Med Biol 2018 ;1103:131-152
The Department of Pediatrics/Human Development, Center For Integrative Toxicology, College of Human Medicine, Michigan State University, East Lansing, MI, USA.
From the transition of single-cell organisms to multicellularity of metazoans, evolutionary pressures selected new genes and phenotypes to cope with the oxygenation of the Earth's environment, especially via the symbiotic acquisition of the mitochondrial organelle. There were many new genes and phenotypes that appeared, namely, stem cells, low-oxygen-micro-environments to house these genes ("niches"), new epigenetic mechanisms to regulate , selectively, the gene repertoire to control proliferation, differentiation, apoptosis, senescence and DNA protection mechanisms, including antioxidant genes and DNA repair. This transition required a critical regulation of the metabolism of glucose to produce energy for both the stem cell quiescent state and the energy-requiring differentiated state. Read More
J Tehran Heart Cent 2018 Apr;13(2):76-79
Department of Pediatrics, Urmia University of Medical Sciences, Urmia, Iran.
Intrapericardial teratomas are rare primary cardiac tumors. These tumors, albeit benign in essence, can be fatal if they exert pressure on the cardiovascular and/or respiratory system. We describe a 34-day-old infant, who needed emergent surgery due to cardiovascular structure compromise. Read More
Neurocirugia (Astur) 2018 Oct 25. Epub 2018 Oct 25.
Servicio de Neurocirugía, Módulo de Columna, Hospital Regional 1° de Octubre, ISSSTE, Mexico City, Mexico.
Spinal cord teratomas are rare. There are few reports of teratomas affecting the cervical spine and their association with spondylotic radiculopathy has not been described. A 59-year-old woman with history of fecal incontinence attended with cervical radicular pain radiating to upper limbs. Read More
J Clin Neurosci 2018 Nov 24. Epub 2018 Nov 24.
Department of Neurology, Prasat Neurological Institute, Bangkok, Thailand. Electronic address:
Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is an acute form of encephalitis with an autoimmune etiology. We aimed to study clinical characteristics and treatment outcomes and assess the predictive factors associated with patient outcome. In this retrospective study, patients who presented with cardinal symptoms of anti-NMDA encephalitis and positive anti-NMDA receptor antibody results in their cerebrospinal fluid were included in the study. Read More
Stem Cell Res 2018 Nov 16;33:255-259. Epub 2018 Nov 16.
Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic. Electronic address:
A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5™ Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. Read More
J Craniofac Surg 2018 Nov 22. Epub 2018 Nov 22.
Department of Plastic Surgery, Baby Memorial Hospital.
Teratomas are rare congenital neoplasms. Head and neck locations of the tumor are uncommon with combined intracranial and extracranial extensions being even more rare. The authors present a case of teratoma involving the temporal, buccal, maxillary, orbital and extending to the intracranial regions, which was successfully managed by surgical resection. Read More
Proteomics Clin Appl 2018 Nov 24:e1800045. Epub 2018 Nov 24.
Proteopath GmbH, Trier 54296, Germany.
Purpose: To present matrix-assisted laser desorption/ionization (MALDI) imaging as a powerful method to highlight various tissue compartments.
Experimental Design: Formalin-fixed paraffin-embedded (FFPE) tissue of a uterine cervix, a pancreas, a duodenum, a teratoma, and a breast cancer tissue microarray (TMA) are analyzed by MALDI imaging and by immunohistochemistry (IHC). Peptide images are visualized and analyzed using FlexImaging and SCiLS Lab software. Read More
Mol Ther 2018 Oct 24. Epub 2018 Oct 24.
Nanomedicine Lab, Faculty of Biology, Medicine and Health, AV Hill Building, The University of Manchester, Manchester M13 9PT, UK; UCL School of Pharmacy, Faculty of Life Sciences, University College London (UCL), London WC1N 1AX, UK. Electronic address:
Overexpression of Oct3/4, Klf4, Sox2, and c-Myc (OKSM) transcription factors can de-differentiate adult cells in vivo. While sustained OKSM expression triggers tumorigenesis through uncontrolled proliferation of toti- and pluripotent cells, transient reprogramming induces pluripotency-like features and proliferation only temporarily, without teratomas. We sought to transiently reprogram cells within mouse skeletal muscle with a localized injection of plasmid DNA encoding OKSM (pOKSM), and we hypothesized that the generation of proliferative intermediates would enhance tissue regeneration after injury. Read More
Pathology 2018 Nov 20. Epub 2018 Nov 20.
Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:
Teratomas show diverse biologic behaviour and prognosis as well as variable histological features. Importantly, post-pubertal testicular teratomas composed of mature components have a potential for malignant behaviour, in contrast to ovarian dermoid cysts and pre-pubertal testicular teratomas which are considered almost always benign. On the other hand, the biological behaviour and histogenesis of extragonadal teratomas are still not fully elucidated. Read More
Front Biosci (Elite Ed) 2019 Jan 1;11:79-88. Epub 2019 Jan 1.
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, Giza, Egypt,
The multifetal reduction (MFR) procedure is usually reserved for high-order multiple pregnancies, and aspirated tissues are typically discarded. In this study, cells obtained from MFR tissue (termed multifetal reduction embryonic cells (MFR-ECs)), were characterized by genotypic and phenotypic analyses and tested by injection under the kidney capsule of nude mice. MFR-ECs were highly proliferative in culture and showed a normal karyotype by microarray CGH. Read More
Arch Plast Surg 2018 Nov 15;45(6):578-582. Epub 2018 Nov 15.
Department of Neurosurgery, Khoula Hospital, Muscat, Sultanate of Oman.
Teratomas can occur in almost any region of the body and are the most common extragonadal germ cell childhood tumors. However, craniofacial teratomas are rare. Craniofacial teratomas can present unique features and cause significant functional and aesthetic concerns. Read More
Asian J Neurosurg 2018 Oct-Dec;13(4):1182-1185
Department of Neurosurgery, University of California, Davis, CA, USA.
Mature thoracic intraspinal teratomas are rare tumors in adults. In this case study, we present a case of intradural, extramedullary teratoma, which was surgically resected. A 50 year old man presented with progressive bilateral leg pain, severe myelopathy and weakness. Read More
Cell Cycle 2018 Nov 20. Epub 2018 Nov 20.
a Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences , University of Copenhagen , Grønnegårdsvej 7, DK-1870 Frederiksberg C , Denmark.
Physiologically and anatomically, humans and pigs share many similarities, which make porcine induced pluripotent stem cells (piPSCs) very attractive for modeling human cell therapy as well as for testing safety of iPSC based cell replacement therapies. To date, several integrative and non-integrative strategies have been reported to successfully generate piPSCs, but all resulting piPSCs had integration of transgenes. The use of integrative methods has the disadvantage of potential lack of silencing or inappropriate re-activation of these genes during differentiation, as well as uncertainty regarding disruption of important genomic regions caused by integration. Read More
Am J Med Genet A 2018 Nov 18. Epub 2018 Nov 18.
Department of Genetics, Institute of Ophthalmology "Conde de Valenciana", Mexico City, Mexico.
SOX2 is a transcription factor that is essential for maintenance of pluripotency and has several conserved roles in early embryonic development. Heterozygous loss-of-function variants in SOX2 are identified in approximately 40% of all cases of bilateral anophthalmia/micropthalmia (A/M). Increasingly SOX2 mutation-positive patients without major eye findings, but with a range of other developmental disorders including autism, mild to moderate intellectual disability with or without structural brain changes, esophageal atresia, urogenital anomalies, and endocrinopathy are being reported, suggesting that the clinical phenotype associated with SOX2 loss is much broader than previously appreciated. Read More
Aging Cell 2018 Nov 18:e12877. Epub 2018 Nov 18.
MRC Human Genetics Unit, MRC, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Induced pluripotent stem cells (IPSCs), with their unlimited regenerative capacity, carry the promise for tissue replacement to counter age-related decline. However, attempts to realize in vivo iPSC have invariably resulted in the formation of teratomas. Partial reprogramming in prematurely aged mice has shown promising results in alleviating age-related symptoms without teratoma formation. Read More
Int J Surg Case Rep 2018 Nov 2;53:299-302. Epub 2018 Nov 2.
Department of Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo City, Yamanashi, Japan.
Introduction: A perforating mediastinal mature teratoma can cause severe inflammation and adhesion; therefore, open surgery is usually performed. Asymptomatic perforation involving a teratoma is very rare. Complete thoracoscopic surgery is often difficult because of inflammation associated with perforation and the frequently large size of a mediastinal mature teratoma. Read More
Urol Oncol 2018 Nov 13. Epub 2018 Nov 13.
Department of Urology, University Hospital Cologne, Cologne, Germany. Electronic address:
Objectives: To evaluate the diagnostic, surgical as well as oncological outcome of patients with a growing teratoma syndrome.
Material And Methods: We performed a retrospective analysis including 680 patients with advanced nonseminomatous germ cell tumors who underwent a postchemotherapy retroperitoneal lymph node dissection. The peri- and postoperative outcome of 22 patients (3%) that fulfilled the criteria of a growing teratoma syndrome were analyzed: nonseminomatous germ cell tumors with increasing tumor size during or after chemotherapy despite normalized or decreasing tumor markers. Read More
Urol Oncol 2018 Nov 13. Epub 2018 Nov 13.
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:
Retroperitoneal lymph node dissection (RPLND) is an important component of the multimodal treatment which cures most patients diagnosed with testicular germ cell tumors. Considering the high cure rates achieved, research focus in recent years has been directed toward improving quality of life and decreasing long-term treatment related sequelae. Consequently, the role of RPLND has evolved over the past 3 decades in both low-stage and advanced testicular cancer. Read More
Cureus 2018 Sep 11;10(9):e3281. Epub 2018 Sep 11.
Pediatrics, University of Illinois College of Medicine At Peoria, Peoria, USA.
A poorly feeding neonate presents the clinician with a diagnostic challenge. Feeding difficulties and irritability may be due to sepsis, congenital heart disease, inborn errors of metabolism, non-accidental head trauma, as well as a vast variety of other pathologies. Teratomas are rare pediatric tumors that can occasionally present in the immediate neonatal period and can manifest in the infant's central nervous system (CNS) with non-specific symptoms of poor feeding, lethargy, and somnolence. Read More
J Indian Assoc Pediatr Surg 2018 Oct-Dec;23(4):228-231
Department of Pediatric Surgery and Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
A teratoma is not an uncommon tumor in the pediatric age group. It has a predilection for specific sites, but a teratoma arising from the hepatoduodenal ligament (HDL) is very rare. Only 15 cases of HDL teratoma have been reported so far. Read More
BMC Surg 2018 Nov 14;18(1):98. Epub 2018 Nov 14.
Department of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.
Background: The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. Read More
Pathol Int 2018 Nov 14. Epub 2018 Nov 14.
Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto 606-8507, Japan.
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare but occasionally fatal limbic encephalitis that may be accompanied by ovarian teratoma. Since the neuroglial tissue within the teratoma may be involved in the pathogenesis of this encephalitis, we attempted morphological and immunohistochemical characterization of the neuroglial tissue in four cases of ovarian teratoma associated with anti-NMDA receptor encephalitis and 12 control cases, i.e. Read More
J Pediatr Surg 2018 Oct 22. Epub 2018 Oct 22.
Department of Women's and Children's Health, Department of Pediatric Surgery, University Children's Hospital, Uppsala, Sweden. Electronic address:
Background/purpose: The aims of this study were to evaluate bowel and urinary tract function, to identify predictors for dysfunctional outcome and to evaluate health-related quality-of life (QoL) in patients treated for sacrococcygeal teratomas (SCT).
Methods: Medical records of patients with SCT born between 1985 and 2015 treated at three Swedish pediatric surgical centers were reviewed. Questionnaires regarding urinary tract function, bowel function and QoL were sent to patients and parents. Read More
Arch Gynecol Obstet 2018 Nov 10. Epub 2018 Nov 10.
Institute of Pathology, Klinikum Bayreuth, Preuschwitzer Strasse 101, 95445, Bayreuth, Germany.
Background: Malignant ascites often develops in patients with ovarian cancer, but there is a lack of more detailed characterization of the different histological subtypes.
Methods: Ascites specimens from patients with ovarian cancer who were treated at Bayreuth Hospital from 2006 to 2015, with follow-up until December 2016, were reevaluated retrospectively.
Results: A total of 191 women (mean age 64 years, range 48-79) were included, of whom 180 (94. Read More
Medicine (Baltimore) 2018 Oct;97(43):e12937
Department of Pathology, Saitama Medical University International Medical Center, Saitama.
Rationale: Malignant melanoma (MM) arising in ovarian cystic teratoma (OCT) is a rare disease with poor prognosis. Recently, immune checkpoint inhibitors of cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) and programmed death 1 (PD-1) have shown promising results in MM. Herein we report a case of MM arising in OCT. Read More
Proteomics Clin Appl 2018 Nov 8:e1800029. Epub 2018 Nov 8.
Bruker Daltonik GmbH, Bremen, Germany.
Purpose: To facilitate the transition of MALDI-MS Imaging (MALDI-MSI) from basic science to clinical application, it is necessary to analyze formalin-fixed paraffin-embedded (FFPE) tissues. Our aim was to improve in-situ tryptic digestion for MALDI-MSI of FFPE samples and determine if similar results would be reproducible if obtained from different sites.
Experimental Design: FFPE tissues (mouse intestine, human ovarian teratoma, tissue microarray of tumor entities sampled from three different sites) were prepared for MALDI-MSI. Read More
Thorac Cancer 2018 Nov 8. Epub 2018 Nov 8.
Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Matsumoto, Japan.
Herein, we report a case of an angiosarcoma in a mediastinal non-seminomatous germ cell tumor that exhibited growing teratoma syndrome during chemotherapy. A 26-year-old man presented with a giant anterior mediastinal mass, which was diagnosed as a non-seminomatous germ cell tumor. The patient was administered three cycles of chemotherapy (bleomycin, etoposide, and cisplatin), but the mass grew despite normalization of tumor markers. Read More
Medicine (Baltimore) 2018 Nov;97(45):e13028
Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital, Hwasun, South Korea.
Rationale: Nasal dermoid cysts are rare congenital lesions and may present as a midline nasal swelling. Nasal dermoid cysts usually present at birth and are commonly diagnosed by 3 years of age. An incidentally detected nasal dermoid cyst in an adult patient is extremely rare. Read More
J Obstet Gynaecol 2018 Nov 8:1-6. Epub 2018 Nov 8.
a Department of Gynaecology , Fernandez Hospital , Hyderabad , India.
This retrospective study aimed to evaluate the sonographic diagnosis and management strategy of symptomatic adnexal torsion at a teaching hospital in Hyderabad, India. All women with abdominal pain and preoperative or operative diagnosis of adnexal torsion from January 2011 to December 2015 were included. A total of 76 women with 78 episodes were included; 28 (36%) occurred during pregnancy. Read More
Case Rep Obstet Gynecol 2018 14;2018:2351809. Epub 2018 Oct 14.
Department of Obstetrics and Gynecology, Seirei Hamamatsu General Hospital, Japan.
A 30-year-old woman (gravida 0) visited our hospital with a complaint of right lower abdominal pain. Transvaginal ultrasonography revealed a 5-cm swollen right ovary, which was suspected to be a mature cystic teratoma. Pelvic examination revealed moderate pain. Read More
Case Rep Oncol Med 2018 3;2018:8460603. Epub 2018 Oct 3.
Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mixed germ cell tumors (GCT) with teratoma components can transform into somatic malignancies which can include histologies outside of traditional germ cell lineages. We describe a case of an 18-year-old man with a metastatic testicular GCT with both mature and immature teratoma components containing malignant transformation into multiple histologies including PNET in the primary testicular tumor and osteosarcoma in a separate pulmonary metastatic lesion. Management with targeted chemotherapy resulted in a durable remission. Read More
Transplant Proc 2018 Nov 11;50(9):2868-2871. Epub 2018 Apr 11.
Research Center of Stem Cell and Regenerative Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, China; Department of Dermatology, Affiliated Hospital of Jiangsu University, Zhenjiang, China. Electronic address:
Objective: Presently, interesting research related to induced pluripotent stem cells (iPSCs) is emerging. However, the development of new therapies and techniques for treatment of refractory diseases is still required in dermatology. We are exploring novel methods to provide stem cell therapy and elucidate research mechanisms underlying troublesome diseases by reprogramming iPSCs from the fibroblasts of keloid lesions from patients in vitro. Read More
J Surg Case Rep 2018 Oct 31;2018(10):rjy279. Epub 2018 Oct 31.
St. Vincent Hospital Indianapolis, Department of Hematology/Oncology, Indianapolis, IN, USA.
Cystic teratomas are rare pluripotent embryonic tumors which most commonly originate in gonadal organs. Extra-gonadal cystic teratomas are exceedingly uncommon, accounting for only 1% of all cystic teratomas, and have been reported in unusual locations including the kidney, mediastinum and liver. These extra-ovarian cystic teratomas have also been known to harbor other neoplasms including carcinoid tumors. Read More
Clin Perinatol 2018 Dec 18;45(4):769-785. Epub 2018 Sep 18.
Department of General Surgery, Greenville Health System, Greenville ENT Associates, 200 Patewood Drive Suite B400, Greenville, SC 29615, USA.
Congenital neck masses can be a developmental anomaly of cystic, solid, or vascular origin. They can also constitute neoplasms, including malignancies, although this is rare in the pediatric population. The history and examination can help quickly narrow the differential diagnosis. Read More
Clin Perinatol 2018 Dec;45(4):609-628
Cochlear Implant Program, Center for Pediatric Airway Disorders, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Congenital causes of airway obstruction once noted at birth are now diagnosed prenatally. The adoption of ex utero intrapartum treatment has allowed for planned airway stabilization on placental support, dramatically decreasing the incidence of hypoxic injury or peripartum demise related to neonatal airway obstruction. Airway access is gained either through laryngoscopy, bronchoscopy, or a surgical airway. Read More
Clin Nucl Med 2018 Nov 3. Epub 2018 Nov 3.
Institute of Pathology, Essen University Hospital, Essen, Germany.
A 67-year-old woman presented with malignant struma ovarii after radical bilateral salpingo-oophorectomy. The surgery revealed a 4.4 cm papillary thyroid carcinoma (follicular variant) within a right-sided ovarian teratoma. Read More
Pediatr Surg Int 2018 Nov 3. Epub 2018 Nov 3.
Department of Pediatric Surgery, International Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Anschutz Medical Campus, 13123 East 16th Avenue, Box 323, Aurora, CO, 80045, USA.
Purpose: Sacral abnormalities range from missing the coccyx, a few sacral vertebrae, or hemi-sacrum, to complete absence with fused iliac bones. The purpose of this study was to review the association between sacral agenesis and fecal incontinence to help inform patient prognosis.
Methods: A retrospective review was performed of patients who presented for bowel management due to sacral agenesis at a tertiary care children's hospital between 2016 and 2017 (n = 10). Read More