24,281 results match your criteria Teratoma Cystic


A giant sacrococcygeal teratoma in adult female: A case report.

Int J Surg Case Rep 2018 Nov 22;54:47-50. Epub 2018 Nov 22.

Department of General Surgery, King Abdulla University Hospital, Faculty of Medicine, Jordan University of Science and Technology, P.O. Box (3030), Irbid, 22110, Jordan. Electronic address:

Introduction: Sacrococcygealteratoma is very rare in adults with only few cases reported in literature. It is a slow growing benign cystic tumor with 1-2% chance for malignant transformation and may attain a huge size causing pressure effect on pelvic and intra-abdominal organs. When grows caudally, it causes discomfort, skin excoriation and cosmetic disfigurement. Read More

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November 2018
3 Reads

Ultrasonic scalpel-assisted endoscopic endonasal surgery of infratemporal fossa: our first impressions.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, HNS&FDRc, University of Insubria, Varese, Italy.

Background: Endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared to traditional open approaches, the endoscopic endonasal approach (EEA) presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.

Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of two rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More

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December 2018
1 Read

Ocular structures in a mature ovarian teratoma.

Am J Ophthalmol Case Rep 2019 Mar 8;13:20-21. Epub 2018 Nov 8.

Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.

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Scintigraphic evaluation of colonic transit in children with constipation using Ga-citrate.

World J Nucl Med 2018 Oct-Dec;17(4):249-252

Hospital de Base do Distrito Federal - Nuclear Medicine Service, Brasília, Brasil.

The aim of this study was to assess the colonic transit in children and teenagers with chronic constipation. Twenty patients from 1.5 to 16 years old were included (mean age = 6. Read More

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December 2018

The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays.

Stem Cell Reports 2018 Nov 27. Epub 2018 Nov 27.

Department of Pathology, Laboratory for Experimental Patho-Oncology, Erasmus MC Cancer Institute, Be-432A, PO Box 2040, 3000 CA Rotterdam, the Netherlands. Electronic address:

Predicting developmental potency and risk of posttransplantation tumor formation by human pluripotent stem cells (hPSCs) and their derivatives largely rely on classical histological analysis of teratomas. Here, we investigated whether an assay based on microRNAs (miRNA) in blood plasma is able to detect potentially malignant elements. Several hPSCs and human malignant germ cell tumor (hGCT) lines were investigated in vitro and in vivo after mouse xenografting. Read More

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November 2018
1 Read

Mismatch repair deficiency is implicated in carcinoma arising from ovarian teratoma.

Pathology 2018 Nov 27. Epub 2018 Nov 27.

Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Hong Kong. Electronic address:

Malignant transformation of benign mature ovarian teratoma can result in a wide spectrum of cancer, including a variety of carcinoma, sarcoma, or melanoma. The role of mismatch repair defects in such malignant transformation is still elusive. In view of current immunotherapy, the role of mismatch repair deficiency can have significant implications on therapeutic strategy. Read More

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November 2018
1 Read

Wilms Tumor of the Ovary: Review of the Literature and Report of 2 Cases.

Int J Gynecol Pathol 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

Primary extrarenal Wilms tumor of the gynecologic tract is extremely rare with scattered case reports occurring in the ovary, uterine corpus and cervix. Only 9 cases of primary ovarian Wilms tumor have been reported to date. Here, we provide an extensive literature review and describe 2 patients with ovarian Wilms tumor: a 36-yr-old female (patient 1) and a 16-yr-old female (patient 2), both presenting with abdominal pain and suspected ovarian torsion. Read More

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December 2018
1 Read

Melanocyte Differentiation From Induced Pluripotent Stem Cells Derived From Human Adipose-Derived Stem Cells.

Ann Plast Surg 2018 Dec 3. Epub 2018 Dec 3.

Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center.

The pigment melanin is produced by melanocytes, is primarily responsible for skin color, and protects it against ultraviolet rays that can cause the destruction of genetic material within the keratinocytes. To elucidate the mechanisms of many diseases associated with melanocytes, such as melanoma and albinism, or burns with uneven pigment distribution, the disease model needs to be established first. In this study, we aimed to construct the melanocyte model from patients in a short period. Read More

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December 2018
1 Read

Minimally invasive drainage of a giant ovarian mucinous cystadenoma associated with a mature cystic teratoma.

J Surg Case Rep 2018 Nov 30;2018(11):rjy322. Epub 2018 Nov 30.

Department of Surgery, Harvard Medical School, The Cambridge Hospital, Cambridge, MA, USA.

A 26-year-old, otherwise healthy female presented to the Emergency Room for the evaluation of abdominal pain. It was immediately apparent that she had a massively distended abdomen. History revealed progressive abdominal distension over several years. Read More

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November 2018

Mediastinal teratoma presenting with hemoptysis and pleuritis misdiagnosed as tuberculosis (empyema).

BMC Pediatr 2018 Dec 4;18(1):382. Epub 2018 Dec 4.

Department of Respiratory Medicine, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Nanlishi Road 56, Xicheng District, Beijing, People's Republic of China.

Background: Mediastinal teratoma is uncommon in children. It can be very difficult to diagnose especially in early stage. Rarely, teratoma may rupture into adjacent structures and lead to lung lesions or pleuritis. Read More

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December 2018

A cardiac mass beyond symptomatic palpitations.

Cardiovasc Pathol 2018 Oct 29;39:1-4. Epub 2018 Oct 29.

Cardiothoracic Surgery Department, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental Carnaxide, Portugal.

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October 2018

Anesthetic Management of an Infant Presenting with an Intrapericardial Tumor: A Case Report.

J Tehran Heart Cent 2018 Apr;13(2):76-79

Department of Pediatrics, Urmia University of Medical Sciences, Urmia, Iran.

Intrapericardial teratomas are rare primary cardiac tumors. These tumors, albeit benign in essence, can be fatal if they exert pressure on the cardiovascular and/or respiratory system. We describe a 34-day-old infant, who needed emergent surgery due to cardiovascular structure compromise. Read More

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April 2018
1 Read

A case report of an intramedullary cervical teratoma in an adult patient with cervical spondylotic radiculopathy.

Neurocirugia (Astur) 2018 Oct 25. Epub 2018 Oct 25.

Servicio de Neurocirugía, Módulo de Columna, Hospital Regional 1° de Octubre, ISSSTE, Mexico City, Mexico.

Spinal cord teratomas are rare. There are few reports of teratomas affecting the cervical spine and their association with spondylotic radiculopathy has not been described. A 59-year-old woman with history of fecal incontinence attended with cervical radicular pain radiating to upper limbs. Read More

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October 2018
1 Read

Abnormal level of consciousness predicts outcomes of patients with anti-NMDA encephalitis.

J Clin Neurosci 2018 Nov 24. Epub 2018 Nov 24.

Department of Neurology, Prasat Neurological Institute, Bangkok, Thailand. Electronic address:

Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is an acute form of encephalitis with an autoimmune etiology. We aimed to study clinical characteristics and treatment outcomes and assess the predictive factors associated with patient outcome. In this retrospective study, patients who presented with cardinal symptoms of anti-NMDA encephalitis and positive anti-NMDA receptor antibody results in their cerebrospinal fluid were included in the study. Read More

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November 2018
2 Reads

Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A.

Stem Cell Res 2018 Nov 16;33:255-259. Epub 2018 Nov 16.

Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic. Electronic address:

A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5™ Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. Read More

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November 2018
2 Reads

Neonatal Teratoma: Craniofacial Treatment.

J Craniofac Surg 2018 Nov 22. Epub 2018 Nov 22.

Department of Plastic Surgery, Baby Memorial Hospital.

Teratomas are rare congenital neoplasms. Head and neck locations of the tumor are uncommon with combined intracranial and extracranial extensions being even more rare. The authors present a case of teratoma involving the temporal, buccal, maxillary, orbital and extending to the intracranial regions, which was successfully managed by surgical resection. Read More

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November 2018
2 Reads

MALDI Imaging for Proteomic Painting of Heterogeneous Tissue Structures.

Proteomics Clin Appl 2018 Nov 24:e1800045. Epub 2018 Nov 24.

Proteopath GmbH, Trier 54296, Germany.

Purpose: To present matrix-assisted laser desorption/ionization (MALDI) imaging as a powerful method to highlight various tissue compartments.

Experimental Design: Formalin-fixed paraffin-embedded (FFPE) tissue of a uterine cervix, a pancreas, a duodenum, a teratoma, and a breast cancer tissue microarray (TMA) are analyzed by MALDI imaging and by immunohistochemistry (IHC). Peptide images are visualized and analyzed using FlexImaging and SCiLS Lab software. Read More

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November 2018
2 Reads

Analysis of chromosome 12p over-representation and clinicopathological features in mediastinal teratomas.

Pathology 2018 Nov 20. Epub 2018 Nov 20.

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Teratomas show diverse biologic behaviour and prognosis as well as variable histological features. Importantly, post-pubertal testicular teratomas composed of mature components have a potential for malignant behaviour, in contrast to ovarian dermoid cysts and pre-pubertal testicular teratomas which are considered almost always benign. On the other hand, the biological behaviour and histogenesis of extragonadal teratomas are still not fully elucidated. Read More

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November 2018
4 Reads

Characterization of embryonic cells obtained from multifetal reduction.

Front Biosci (Elite Ed) 2019 Jan 1;11:79-88. Epub 2019 Jan 1.

Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, Giza, Egypt,

The multifetal reduction (MFR) procedure is usually reserved for high-order multiple pregnancies, and aspirated tissues are typically discarded. In this study, cells obtained from MFR tissue (termed multifetal reduction embryonic cells (MFR-ECs)), were characterized by genotypic and phenotypic analyses and tested by injection under the kidney capsule of nude mice. MFR-ECs were highly proliferative in culture and showed a normal karyotype by microarray CGH. Read More

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January 2019
5 Reads

Proboscis lateralis: A case report of a rare giant craniofacial teratoma in an infant.

Arch Plast Surg 2018 Nov 15;45(6):578-582. Epub 2018 Nov 15.

Department of Neurosurgery, Khoula Hospital, Muscat, Sultanate of Oman.

Teratomas can occur in almost any region of the body and are the most common extragonadal germ cell childhood tumors. However, craniofacial teratomas are rare. Craniofacial teratomas can present unique features and cause significant functional and aesthetic concerns. Read More

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November 2018
3 Reads

Adult Thoracic Intradural Exophytic Mature Teratoma: Case Report and Literature Review.

Asian J Neurosurg 2018 Oct-Dec;13(4):1182-1185

Department of Neurosurgery, University of California, Davis, CA, USA.

Mature thoracic intraspinal teratomas are rare tumors in adults. In this case study, we present a case of intradural, extramedullary teratoma, which was surgically resected. A 50 year old man presented with progressive bilateral leg pain, severe myelopathy and weakness. Read More

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November 2018

Extension of the mutational and clinical spectrum of SOX2 related disorders: Description of six new cases and a novel association with suprasellar teratoma.

Am J Med Genet A 2018 Nov 18. Epub 2018 Nov 18.

Department of Genetics, Institute of Ophthalmology "Conde de Valenciana", Mexico City, Mexico.

SOX2 is a transcription factor that is essential for maintenance of pluripotency and has several conserved roles in early embryonic development. Heterozygous loss-of-function variants in SOX2 are identified in approximately 40% of all cases of bilateral anophthalmia/micropthalmia (A/M). Increasingly SOX2 mutation-positive patients without major eye findings, but with a range of other developmental disorders including autism, mild to moderate intellectual disability with or without structural brain changes, esophageal atresia, urogenital anomalies, and endocrinopathy are being reported, suggesting that the clinical phenotype associated with SOX2 loss is much broader than previously appreciated. Read More

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November 2018
3 Reads

Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity.

Aging Cell 2018 Nov 18:e12877. Epub 2018 Nov 18.

MRC Human Genetics Unit, MRC, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

Induced pluripotent stem cells (IPSCs), with their unlimited regenerative capacity, carry the promise for tissue replacement to counter age-related decline. However, attempts to realize in vivo iPSC have invariably resulted in the formation of teratomas. Partial reprogramming in prematurely aged mice has shown promising results in alleviating age-related symptoms without teratoma formation. Read More

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November 2018

Mediastinal mature teratoma perforating the right lung that was successfully resected with complete thoracoscopic surgery: A case report.

Int J Surg Case Rep 2018 Nov 2;53:299-302. Epub 2018 Nov 2.

Department of Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo City, Yamanashi, Japan.

Introduction: A perforating mediastinal mature teratoma can cause severe inflammation and adhesion; therefore, open surgery is usually performed. Asymptomatic perforation involving a teratoma is very rare. Complete thoracoscopic surgery is often difficult because of inflammation associated with perforation and the frequently large size of a mediastinal mature teratoma. Read More

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November 2018
3 Reads

Diagnosis and management of the growing teratoma syndrome: A single-center experience and review of the literature.

Urol Oncol 2018 Nov 13. Epub 2018 Nov 13.

Department of Urology, University Hospital Cologne, Cologne, Germany. Electronic address:

Objectives: To evaluate the diagnostic, surgical as well as oncological outcome of patients with a growing teratoma syndrome.

Material And Methods: We performed a retrospective analysis including 680 patients with advanced nonseminomatous germ cell tumors who underwent a postchemotherapy retroperitoneal lymph node dissection. The peri- and postoperative outcome of 22 patients (3%) that fulfilled the criteria of a growing teratoma syndrome were analyzed: nonseminomatous germ cell tumors with increasing tumor size during or after chemotherapy despite normalized or decreasing tumor markers. Read More

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November 2018
8 Reads

Current controversies on the role of retroperitoneal lymphadenectomy for testicular cancer.

Urol Oncol 2018 Nov 13. Epub 2018 Nov 13.

Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

Retroperitoneal lymph node dissection (RPLND) is an important component of the multimodal treatment which cures most patients diagnosed with testicular germ cell tumors. Considering the high cure rates achieved, research focus in recent years has been directed toward improving quality of life and decreasing long-term treatment related sequelae. Consequently, the role of RPLND has evolved over the past 3 decades in both low-stage and advanced testicular cancer. Read More

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November 2018
6 Reads

Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female.

Cureus 2018 Sep 11;10(9):e3281. Epub 2018 Sep 11.

Pediatrics, University of Illinois College of Medicine At Peoria, Peoria, USA.

A poorly feeding neonate presents the clinician with a diagnostic challenge. Feeding difficulties and irritability may be due to sepsis, congenital heart disease, inborn errors of metabolism, non-accidental head trauma, as well as a vast variety of other pathologies. Teratomas are rare pediatric tumors that can occasionally present in the immediate neonatal period and can manifest in the infant's central nervous system (CNS) with non-specific symptoms of poor feeding, lethargy, and somnolence. Read More

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September 2018
1 Read

Teratoma in the Hepatoduodenal Ligament.

J Indian Assoc Pediatr Surg 2018 Oct-Dec;23(4):228-231

Department of Pediatric Surgery and Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.

A teratoma is not an uncommon tumor in the pediatric age group. It has a predilection for specific sites, but a teratoma arising from the hepatoduodenal ligament (HDL) is very rare. Only 15 cases of HDL teratoma have been reported so far. Read More

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November 2018
2 Reads

Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report.

BMC Surg 2018 Nov 14;18(1):98. Epub 2018 Nov 14.

Department of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.

Background: The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. Read More

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November 2018
3 Reads

Histopathological characterization of the neuroglial tissue in ovarian teratoma associated with anti-N-methyl-D-aspartate (NMDA) receptor encephalitis.

Pathol Int 2018 Nov 14. Epub 2018 Nov 14.

Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto 606-8507, Japan.

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare but occasionally fatal limbic encephalitis that may be accompanied by ovarian teratoma. Since the neuroglial tissue within the teratoma may be involved in the pathogenesis of this encephalitis, we attempted morphological and immunohistochemical characterization of the neuroglial tissue in four cases of ovarian teratoma associated with anti-NMDA receptor encephalitis and 12 control cases, i.e. Read More

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November 2018
4 Reads

Functional outcome and health-related quality of life in patients with sacrococcygeal teratoma - a Swedish multicenter study.

J Pediatr Surg 2018 Oct 22. Epub 2018 Oct 22.

Department of Women's and Children's Health, Department of Pediatric Surgery, University Children's Hospital, Uppsala, Sweden. Electronic address:

Background/purpose: The aims of this study were to evaluate bowel and urinary tract function, to identify predictors for dysfunctional outcome and to evaluate health-related quality-of life (QoL) in patients treated for sacrococcygeal teratomas (SCT).

Methods: Medical records of patients with SCT born between 1985 and 2015 treated at three Swedish pediatric surgical centers were reviewed. Questionnaires regarding urinary tract function, bowel function and QoL were sent to patients and parents. Read More

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October 2018

Malignant ascites occurs most often in patients with high-grade serous papillary ovarian cancer at initial diagnosis: a retrospective analysis of 191 women treated at Bayreuth Hospital, 2006-2015.

Arch Gynecol Obstet 2018 Nov 10. Epub 2018 Nov 10.

Institute of Pathology, Klinikum Bayreuth, Preuschwitzer Strasse 101, 95445, Bayreuth, Germany.

Background: Malignant ascites often develops in patients with ovarian cancer, but there is a lack of more detailed characterization of the different histological subtypes.

Methods: Ascites specimens from patients with ovarian cancer who were treated at Bayreuth Hospital from 2006 to 2015, with follow-up until December 2016, were reevaluated retrospectively.

Results: A total of 191 women (mean age 64 years, range 48-79) were included, of whom 180 (94. Read More

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November 2018
9 Reads

Immune checkpoint inhibitors of CTLA4 and PD-1 for malignant melanoma arising in ovarian cystic teratoma: A case report.

Medicine (Baltimore) 2018 Oct;97(43):e12937

Department of Pathology, Saitama Medical University International Medical Center, Saitama.

Rationale: Malignant melanoma (MM) arising in ovarian cystic teratoma (OCT) is a rare disease with poor prognosis. Recently, immune checkpoint inhibitors of cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) and programmed death 1 (PD-1) have shown promising results in MM. Herein we report a case of MM arising in OCT. Read More

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October 2018
10 Reads

Site-to-Site Reproducibility and Spatial Resolution in MALDI-MSI of Peptides from Formalin-Fixed Paraffin-Embedded Samples.

Proteomics Clin Appl 2018 Nov 8:e1800029. Epub 2018 Nov 8.

Bruker Daltonik GmbH, Bremen, Germany.

Purpose: To facilitate the transition of MALDI-MS Imaging (MALDI-MSI) from basic science to clinical application, it is necessary to analyze formalin-fixed paraffin-embedded (FFPE) tissues. Our aim was to improve in-situ tryptic digestion for MALDI-MSI of FFPE samples and determine if similar results would be reproducible if obtained from different sites.

Experimental Design: FFPE tissues (mouse intestine, human ovarian teratoma, tissue microarray of tumor entities sampled from three different sites) were prepared for MALDI-MSI. Read More

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November 2018
1 Read
2.680 Impact Factor

Development of angiosarcoma in a mediastinal non-seminomatous germ cell tumor that exhibited growing teratoma syndrome during chemotherapy.

Thorac Cancer 2018 Nov 8. Epub 2018 Nov 8.

Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Matsumoto, Japan.

Herein, we report a case of an angiosarcoma in a mediastinal non-seminomatous germ cell tumor that exhibited growing teratoma syndrome during chemotherapy. A 26-year-old man presented with a giant anterior mediastinal mass, which was diagnosed as a non-seminomatous germ cell tumor. The patient was administered three cycles of chemotherapy (bleomycin, etoposide, and cisplatin), but the mass grew despite normalization of tumor markers. Read More

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November 2018
7 Reads

Dermoid cyst of nasal septum in an adult patient: A case report.

Medicine (Baltimore) 2018 Nov;97(45):e13028

Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital, Hwasun, South Korea.

Rationale: Nasal dermoid cysts are rare congenital lesions and may present as a midline nasal swelling. Nasal dermoid cysts usually present at birth and are commonly diagnosed by 3 years of age. An incidentally detected nasal dermoid cyst in an adult patient is extremely rare. Read More

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November 2018

Acute Abdomen due to Mutual Tangle of Two Small Paratubal Cysts.

Case Rep Obstet Gynecol 2018 14;2018:2351809. Epub 2018 Oct 14.

Department of Obstetrics and Gynecology, Seirei Hamamatsu General Hospital, Japan.

A 30-year-old woman (gravida 0) visited our hospital with a complaint of right lower abdominal pain. Transvaginal ultrasonography revealed a 5-cm swollen right ovary, which was suspected to be a mature cystic teratoma. Pelvic examination revealed moderate pain. Read More

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October 2018
10 Reads

Malignant Transformation of Testicular Teratoma to PNET, Adenocarcinoma, and Osteosarcoma with Complete Remission after Surgery and Combination Chemotherapy in a Young Adult Male.

Case Rep Oncol Med 2018 3;2018:8460603. Epub 2018 Oct 3.

Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Mixed germ cell tumors (GCT) with teratoma components can transform into somatic malignancies which can include histologies outside of traditional germ cell lineages. We describe a case of an 18-year-old man with a metastatic testicular GCT with both mature and immature teratoma components containing malignant transformation into multiple histologies including PNET in the primary testicular tumor and osteosarcoma in a separate pulmonary metastatic lesion. Management with targeted chemotherapy resulted in a durable remission. Read More

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October 2018
2 Reads

Development of Individualized Induced Pluripotent Stem Cells From Fibroblasts of Keloid Lesions in Patients.

Transplant Proc 2018 Nov 11;50(9):2868-2871. Epub 2018 Apr 11.

Research Center of Stem Cell and Regenerative Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, China; Department of Dermatology, Affiliated Hospital of Jiangsu University, Zhenjiang, China. Electronic address:

Objective: Presently, interesting research related to induced pluripotent stem cells (iPSCs) is emerging. However, the development of new therapies and techniques for treatment of refractory diseases is still required in dermatology. We are exploring novel methods to provide stem cell therapy and elucidate research mechanisms underlying troublesome diseases by reprogramming iPSCs from the fibroblasts of keloid lesions from patients in vitro. Read More

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November 2018
4 Reads

Resection of a mature cystic teratoma of the liver harboring a carcinoid tumor.

J Surg Case Rep 2018 Oct 31;2018(10):rjy279. Epub 2018 Oct 31.

St. Vincent Hospital Indianapolis, Department of Hematology/Oncology, Indianapolis, IN, USA.

Cystic teratomas are rare pluripotent embryonic tumors which most commonly originate in gonadal organs. Extra-gonadal cystic teratomas are exceedingly uncommon, accounting for only 1% of all cystic teratomas, and have been reported in unusual locations including the kidney, mediastinum and liver. These extra-ovarian cystic teratomas have also been known to harbor other neoplasms including carcinoid tumors. Read More

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October 2018
5 Reads

Fetal Evaluation and Airway Management.

Clin Perinatol 2018 Dec;45(4):609-628

Cochlear Implant Program, Center for Pediatric Airway Disorders, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

Congenital causes of airway obstruction once noted at birth are now diagnosed prenatally. The adoption of ex utero intrapartum treatment has allowed for planned airway stabilization on placental support, dramatically decreasing the incidence of hypoxic injury or peripartum demise related to neonatal airway obstruction. Airway access is gained either through laryngoscopy, bronchoscopy, or a surgical airway. Read More

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December 2018
3 Reads

Complete Remission After Single Radioiodine Therapy in Malignant Struma Ovarii With Bone and Lymph Node Metastases.

Clin Nucl Med 2018 Nov 3. Epub 2018 Nov 3.

Institute of Pathology, Essen University Hospital, Essen, Germany.

A 67-year-old woman presented with malignant struma ovarii after radical bilateral salpingo-oophorectomy. The surgery revealed a 4.4 cm papillary thyroid carcinoma (follicular variant) within a right-sided ovarian teratoma. Read More

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November 2018
5 Reads

Perioperative management of an anterior mediastinal teratoma in an infant: one more tool in the toolbox.

BMJ Case Rep 2018 Nov 1;2018. Epub 2018 Nov 1.

Surgery, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, USA.

Anterior mediastinal masses present a significant challenge in the perioperative period. Standard anaesthetic induction and airway management are often not feasible due to the risk of complete respiratory and/or cardiovascular collapse. Invasive manoeuvres, such as extracorporeal membrane oxygenation, cardiac bypass, or tracheal or bronchial stenting, are sometimes not applicable due to significant anatomic aberration. Read More

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November 2018
2 Reads

Treatment Options for Anti-N-methyl-D-aspartate Receptor Encephalitis.

Neurodiagn J 2018 Nov 2:1-9. Epub 2018 Nov 2.

a CISSS Montérégie Center, Charles-Le Moyne Hospital, Neurology Department , Sherbrooke University Affiliated , Greenfield Park , Québec , Canada.

Anti-NMDAR encephalitis is an autoimmune limbic disorder with an unknown cause, which affects mostly young women. Behavioral changes, seizures, orofacial muscle contractions, and memory impairment are usually observed. The variability of the symptoms depends on which part of the brain is inflamed. Read More

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November 2018
4 Reads

Generation of Induced Pluripotent Stem Cells from Human Epidermal Keratinocytes.

Cell Reprogram 2018 Dec 2;20(6):356-364. Epub 2018 Nov 2.

1 Department of Dermatology, The Third Affiliated Hospital of Suzhou University , Changzhou, China .

Induced pluripotent stem cells (iPSCs) play an important role in cell replacement therapy. Several studies have shown that keratinocytes are promising reprogrammed cells. We easily and efficiently enriched epidermal stem cells by attaching them for a limited time in culture dishes. Read More

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December 2018
5 Reads

Testis sparing surgery for small testicular masses and frozen section assessment.

Cent European J Urol 2018 16;71(3):304-309. Epub 2018 Aug 16.

Department of Urology, Frimley Health NHS Foundation Trust, Wexham Park Hospital Slough, Berkshire, United Kingdom.

Introduction: We present our experience with patients who had suspected testicular masses, managed by a frozen section assessment and testicular sparing surgery.

Material And Methods: We performed a retrospective review of all patients over the last 5 years, who underwent a frozen section assessment and testicular sparing surgery for small testicular lesions. The frozen section assessment was compared with the final histology. Read More

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August 2018
2 Reads

Squamous cell carcinoma arising in a partially ruptured giant mature cystic teratoma: A case report.

Radiol Case Rep 2019 Jan 24;14(1):97-102. Epub 2018 Oct 24.

Cooper University Hospital, Department of Diagnostic Radiology, One Cooper Plaza, Camden, NJ 08103, USA.

Mature cystic teratomas are the most common ovarian germ cell tumors and represent 70% of the benign ovarian tumors occurring in women under age 30. In less than 2% of cases, these tumors can transform into malignancies. Squamous cell carcinoma arises most frequently from these tumors (in 80% of cases). Read More

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January 2019
2 Reads

Primitive neuroectodermal tumor transformation of testicular teratoma.

Urol Ann 2018 Oct-Dec;10(4):413-415

Department of Urology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

Malignant transformation of teratoma develops in a small subset of testis cancer patients. Primitive neuroectodermal tumor represents a highly malignant component of testicular germ cell tumors. It is a rare clinical entity which is characterized by a high risk of disease progression and death. Read More

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November 2018
5 Reads