297,283 results match your criteria Temporal Giant Cell Arteritis
Chemosphere 2018 Dec 6;219:546-556. Epub 2018 Dec 6.
Programa de Pós-Graduação Em Ecologia e Recursos Naturais, Laboratório de Ciências Ambientais, Centro de Biociências e Biotecnologia, Universidade Estadual Do Norte Fluminense Darcy Ribeiro, Av. Alberto Lamego, 2000 - Parque Califórnia, CEP: 28013-602, Campos Dos Goytacazes, Rio de Janeiro, Brazil.
The increase in global demand for electric energy is reflected in plans to construct numerous hydroelectric dams in South America that can cause chronic ecological impacts if not built and managed correctly. One of the main impacts generated by hydropower dams is the accumulation of Hg chemical species in their reservoir compartments and the downstream transport of these contaminants. Hg circulation in these environments has been studied for 27 years and this review brings a synthesis of the dynamics that are now well established, so that future studies can focus on gaps and inconsistent results in the literature. Read More
Thromb Res 2018 Dec 8;174:27-33. Epub 2018 Dec 8.
Department of Cardiology, EA3920, University Hospital Besançon, Boulevard Fleming, 25030 Besançon, France. Electronic address:
Background: Data regarding the use of direct oral anticoagulants (DOACs) for the treatment of acute pulmonary embolism (PE) are sparse. We conducted a prospective multicentre registry study to describe patterns of DOAC prescription for the treatment of acute PE, and the associated risk of 6-month adverse events in daily practice.
Methods: We included all PE patients discharged since the availability of DOACs for the dedicated indication of acute PE treatment. Read More
J Psychiatr Res 2018 Dec 7;109:178-184. Epub 2018 Dec 7.
Department of Psychology, Michigan State University, 316 Physics Rd #262, East Lansing, MI, 48824, USA.
During adolescence, peer approval becomes increasingly important and may be perceived as contingent upon appearance in girls. Concurrently, girls experience hormonal changes, including an increase in progesterone. Progesterone has been implicated in affiliative behavior but inconsistently associated with body image concerns. Read More
Plant Physiol Biochem 2018 Dec 4;135:174-181. Epub 2018 Dec 4.
Division of Viticulture and Pomology, Department of Crop Sciences, University of Natural Resources and Life Sciences (BOKU), Vienna, Konrad Lorenz Str. 24, 3430, Tulln, Austria.
Many plants respond to herbivore attacks by the formation of secondary metabolites, such as polyphenols. Grape phylloxera (Daktulosphaira vitifoliaeFitch) induces organoid root galls on fibrous root tips of tolerant Vitis spp. rootstocks. Read More
Psychiatry Res 2018 Dec 7;271:535-540. Epub 2018 Dec 7.
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Mental Illness Research, Education, and Clinical Center (VISN 2), James J. Peters VA Medical Center, 130 West Kingsbridge Road, Room 6A-44, Bronx, NY, United States.
This is a selective review of the work of Buchsbaum and colleagues. It revisits and pays tribute to four decades of publications employing positron emission tomography (PET) with fluorodeoxyglucose (FDG) to examine the neurobiology of schizophrenia-spectrum disorders (including schizotypal personality disorder (SPD) and schizophrenia). Beginning with a landmark FDG-PET study in 1982 reporting hypofrontality in unmedicated schizophrenia patients, Buchsbaum and colleagues published high-impact work on regional glucose metabolic rate (GMR) abnormalities in the spectrum. Read More
Neuroimage 2018 Dec 12. Epub 2018 Dec 12.
Fetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA; Division of Newborn Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA. Electronic address:
Accurate parcellation and labeling of primary cortical sulci in the human fetal brain is useful for regional analysis of brain development. However, human fetal brains show large spatio-temporal changes in brain size, cortical folding patterns, and relative position/size of cortical regions, making accurate automatic sulcal labeling challenging. Here, we introduce a novel sulcal labeling method for the fetal brain using spatio-temporal gyrification information from multiple fetal templates. Read More
Behav Processes 2018 Dec 12. Epub 2018 Dec 12.
School of Life Sciences, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg 3209, South Africa. Electronic address:
Understanding the effects of anthropogenic disturbance on species' behaviour is crucial for conservation planning, considering the extent of habitat loss. We investigated the influence of anthropogenic disturbances including agriculture, urbanisation, protected areas, and the presence of novel predators, on the temporal and spatial behaviour of sympatric forest antelope (Tragelaphus scriptus, Philantomba monticola, Sylvicapra grimmia, and Cephalophus natalensis) in an anthropogenic matrix containing forest fragments in the Indian Ocean Coastal Belt of South Africa. We integrated land-use types with camera-trap data and compared activity patterns using circular statistics and occupancy modelling. Read More
Glob Chang Biol 2018 Dec 15. Epub 2018 Dec 15.
Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla, China.
It is critical to accurately estimate carbon (C) turnover time as it dominates the uncertainty in ecosystem C sinks and their response to future climate change. In the absence of direct observations of ecosystem C losses, C turnover times are commonly estimated under the steady-state assumption (SSA), which has been applied across a large range of temporal and spatial scales including many at which the validity of the assumption is likely to be violated. However the errors associated with improperly applying SSA to estimate C turnover time and its covariance with climate as well as ecosystem C sequestrations have yet to be fully quantified. Read More
J Magn Reson Imaging 2018 Dec 15. Epub 2018 Dec 15.
Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.
Background: Contrast-enhanced magnetic resonance imaging (CE-MRI) of the breast is highly sensitive for breast cancer detection. Multichannel coils and 3T scanners can increase signal, spatial, and temporal resolution. In addition, the T -reduction effect of a gadolinium-based contrast agent (GBCA) is higher at 3T. Read More
Actas Esp Psiquiatr 2018 Nov 1;46(6):234-41. Epub 2018 Nov 1.
Ph. D., Director of the Department of Psychiatry East of the Faculty of Medicine of the University of Chile.
After defining that fundamental element of psychic life which is intentionality, based on original descriptions by Franz Brentano and Edmund Husserl, the authors try to show the way in which this phenomenon is respectively altered in schizophrenia and in depression. For understanding what occurs with respect to this in schizophrenia it is first necessary to focus on what Husserl calls “the consciousness of the interior or immanent time”. The current of consciousness is not a mere succession of “nows”, but of a process of dynamic self-organization, which begins to be developed as, for example, a lecture or a melody is heard. Read More
Matern Child Health J 2018 Dec 14. Epub 2018 Dec 14.
Department of Anesthesiology, Columbia University College of Physicians and Surgeons, 622 West 168th Street, PH5-505, New York, NY, 10032, USA.
Objectives This study examined the prevalence and temporal trends in (a) pulmonary hypertension (PH) during pregnancy and (b) mortality and morbidity during pregnancy with and without PH. Methods This was a retrospective observational study of the 2003-2014 New York State Inpatient Database. PH was categorized as primary or secondary and pregnancy as loss or termination of pregnancy, preterm birth, or term birth. Read More
Med Biol Eng Comput 2018 Dec 14. Epub 2018 Dec 14.
Sorbonne University, Université de Technologie de Compiègne, CNRS, UMR 7338 Biomechanics and Bioengineering, Centre de recherche Royallieu, Compiègne Cedex, France.
Skeletal muscle forces may be estimated using rigid musculoskeletal models and neural networks. Neural network (NN) approach has the advantages of real-time estimation ability and promising prediction accuracy. However, most of the developed NN models are based on conventional feedforward NNs, which do not take dynamic temporal relationships of the muscle force profiles into consideration. Read More
Eur Radiol 2018 Dec 14. Epub 2018 Dec 14.
Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, OX3 7DQ, Oxford, UK.
Purpose: To derive lobar ventilation in patients with chronic obstructive pulmonary disease (COPD) using a rapid time-series hyperpolarized xenon-129 (HPX) magnetic resonance imaging (MRI) technique and compare this to ventilation/perfusion single-photon emission computed tomography (V/Q-SPECT), correlating the results with high-resolution computed tomography (CT) and pulmonary function tests (PFTs).
Materials And Methods: Twelve COPD subjects (GOLD stages I-IV) participated in this study and underwent HPX-MRI, V/Q-SPECT/CT, high-resolution CT, and PFTs. HPX-MRI was performed using a novel time-series spiral k-space sampling approach. Read More
Exp Brain Res 2018 Dec 14. Epub 2018 Dec 14.
Department of Hearing, Speech, and Language Sciences, Gallaudet University, 800 Florida Ave, Washington, DC, USA.
The sensorimotor dorsal stream is known to activate in both overt and covert speech production. However, overt production produces sensory consequences that are absent during covert production. Thus, the purpose of the current study is to investigate differences in dorsal stream activity between these two production conditions across the time course of utterances. Read More
Bull Environ Contam Toxicol 2018 Dec 14. Epub 2018 Dec 14.
Mi'gmawe'l Tplu'taqnn Incorporated (MTI), 40 MicMac Road, Eel Ground, Miramichi, NB, E1V4B1, Canada.
The diets of Indigenous people rely on food and medicinal plants harvested directly from the land and there is increasing concern from Indigenous knowledge holders over changes to the appearance and flavor of wild harvested food and medicinal plants. We collected samples of muskrat root, considered an important medicinal plant, at 11 traditional collection locations to quantify contaminants of concern. There were no spatial or temporal trends apparent and the risk via consumption was found to be very low. Read More
Sci Rep 2018 Dec 14;8(1):17848. Epub 2018 Dec 14.
Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente, Enschede, Netherlands.
Knowledge of the temporal trends and spatial patterns will have significant implications for effective preparedness in future epidemics. Our objective was to investigate the temporal trends and the nature of the spatial interaction of cholera incidences, dwelling on an outbreak in the Kumasi Metropolis, Ghana. We developed generalized nonparametric and segmented regression models to describe the epidemic curve. Read More
J Perinatol 2018 Dec 14. Epub 2018 Dec 14.
Department of Radiology, Dalhousie University and the IWK Health Centre, Halifax, NS, Canada.
Objective: To identify the temporal trends, risk factors and outcomes of cystic white matter injury (WMI) detected by ultrasound in a population-based cohort of very preterm infants (VPI) with a minimal risk of selection bias.
Study Design: All live-born VPIs between 22 and < 31 weeks gestational age born in Nova Scotia, Canada from 1993 to 2013.
Results: Cystic WMI was identified in 87 (7%) out of 1184 eligible infants. Read More
Sci Rep 2018 Dec 14;8(1):17866. Epub 2018 Dec 14.
Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA.
This study was performed to test the repeatability and reproducibility of measurements of peri-papillary capillaries from four optical coherence tomography angiography (OCTA) devices. 109 healthy eyes were imaged with four OCTA devices (Spectralis, Optovue, Triton and Cirrus). A 3 × 3 mm scan pattern centered on the disc was repeated twice by each device. Read More
J Neurosci 2018 Dec 14. Epub 2018 Dec 14.
Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Performance-based incentives tend to increase an individual's motivation, resulting in enhancements in behavioral output. While much work has focused on understanding how the brain's reward circuitry influences incentive motivated performance, fewer studies have investigated how such reward representations act on the motor system. Here we measured motor cortical excitability with transcranial magnetic stimulation (TMS) while female and male human participants performed a motoric incentive motivation task for prospective monetary gains and losses. Read More
J Immunol 2018 Dec 14. Epub 2018 Dec 14.
Department of Anesthesiology, University of Colorado Denver, Aurora, CO 80045;
Aging of established antiviral T cell memory can foster a series of progressive adaptations that paradoxically improve rather than compromise protective CD8 T cell immunity. We now provide evidence that this gradual evolution, the pace of which is contingent on the precise context of the primary response, also impinges on the molecular mechanisms that regulate CD8 memory T cell (T) homeostasis. Over time, CD8 T generated in the wake of an acute infection with the natural murine pathogen lymphocytic choriomeningitis virus become more resistant to apoptosis and acquire enhanced cytokine responsiveness without adjusting their homeostatic proliferation rates; concurrent metabolic adaptations promote increased CD8 T quiescence and fitness but also impart the reacquisition of a partial effector-like metabolic profile; and a gradual redistribution of aging CD8 T from blood and nonlymphoid tissues to lymphatic organs results in CD8 T accumulations in bone marrow, splenic white pulp, and, particularly, lymph nodes. Read More
Diabetes Care 2018 Dec 14. Epub 2018 Dec 14.
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN
Objective: This study investigated the temporal dynamics of pancreas volume and microstructure in children and adolescents with recent-onset type 1 diabetes (T1D) and individuals without diabetes, including a subset expressing autoantibodies associated with the early stages of T1D.
Research Design And Methods: MRI was performed in individuals with recent-onset stage 3 T1D ( = 51; median age 13 years) within 100 days after diagnosis (mean 67 days), 6 months, and 1 year postdiagnosis. Longitudinal MRI measurements were also made in similarly aged control participants ( = 57) and in autoantibody-positive individuals without diabetes ( = 20). Read More
Neuroimage Clin 2018 Dec 5. Epub 2018 Dec 5.
Center for Imaging Science, The Johns Hopkins University, Baltimore, MD 21218, USA; Institute for Computational Medicine, The Johns Hopkins University, Baltimore, MD 21218, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD 21218, USA.
This study examines the atrophy rates of subjects with mild cognitive impairment (MCI) compared to controls in four regions within the medial temporal lobe: the transentorhinal cortex (TEC), entorhinal cortex (ERC), hippocampus, and amygdala. These regions were manually segmented and then corrected for undesirable longitudinal variability via Large Deformation Diffeomorphic Metric Mapping (LDDMM) based longitudinal diffeomorphometry. Diffeomorphometry techniques were used to compare thickness measurements in the TEC with the ERC. Read More
Curr Opin Insect Sci 2018 Aug 16;28:98-104. Epub 2018 May 16.
Department of Entomology, 2475 TAMU, Texas A&M University, College Station, TX 77843, USA.
Citizen-collected arthropod vectors are useful for epidemiological studies of vector-borne disease, especially since the vectors encountered by the public are the subset of vectors in nature that have a disproportionate impact on health. Programs integrating educational efforts with collecting efforts may be particularly effective for public health initiatives, resulting in an empowered public with knowledge of vector-borne disease prevention. Citizen science programs have been successfully implemented for the collection of unprecedented sample sets of mosquitos, ticks, and triatomines. Read More
Arch Iran Med 2018 Nov 1;21(11):544-546. Epub 2018 Nov 1.
Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.
Myeloid sarcoma (MS) is a solid extra-medullary tumor of immature myeloid cells which could occur before, during or after remission of acute leukemia at any site on the body. Owing to variation in differential diagnosis, pathologic evaluation and immunohistochemical staining are essential for definitive diagnosis. Rarely, MS has been shown as an isolated extramedullary relapse (iEMR) after allogeneic stem cell transplantation (allo-SCT), which often does not necessarily result in bone marrow involvement. Read More
Int J Environ Res Public Health 2018 Dec 13;15(12). Epub 2018 Dec 13.
College of Landscape Architecture, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China.
Air pollution has become a critical issue in the urban areas of southeastern China in recent years. A complete understanding of the tempo-spatial characteristics of air pollution can help the public and governmental bodies manage their lives and work better. In this study, data for six criteria air pollutants (including particulate matter (PM, PM), carbon monoxide (CO), sulfur dioxide (SO₂), nitrogen dioxide (NO₂) and ozone (O₃)) from 37 sites in nine major cities within Fujian Province, China were collected between January 2015 to December 2016, and analyzed. Read More
Psychiatry Res 2018 Dec 30;270:786-791. Epub 2018 Oct 30.
Department of Ophthalmology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, No. 26 Shengli Street, Hubei Province, Wuhan 430014, China. Electronic address:
Studies using optical coherence tomography (OCT) to compare retinal nerve fiber layer thickness in subjects with schizophrenia and healthy controls have yielded inconsistent results. We aimed to compare changes in retinal nerve fiber layer thickness in schizophrenia and healthy controls via a meta-analysis. Relevant studies were selected via an electronic search of the Cochrane Controlled Trials Register, Pubmed, and Embase. Read More
Tree Physiol 2018 Dec 14. Epub 2018 Dec 14.
School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney NSW, Australia.
Rapid, reliable tools are needed to infer physiological and nutritional health for managing forest systems. Understanding the processes governing tree health is central to the development of these tools. Non-foliar approaches such as the collection of phloem sap reflect processes governing both the use and acquisition of plant water and nutrients at a wide range of temporal (diurnal to seasonal) and spatial (canopy) scales. Read More
Chemosphere 2018 Nov 27;219:409-417. Epub 2018 Nov 27.
Laboratório de Radioisótopos, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho s/n, Bloco G0, Sala 60, Subsolo, Rio de Janeiro, 21941-902, Brazil.
Our main goal was to investigate the potential accumulation of fluoroquinolones (FQs) in agricultural soils over extended periods of land use, predicting leaching and estimating risk quotients for soil microorganisms. Short to long-term of poultry litter fertilization (<1-30 years) were evaluated for enrofloxacin (ENR) and ciprofloxacin (CIP) input, in addition to the emergence of plasmid-mediated quinolone resistance (PMQR) genes. High FQs concentration (range 0. Read More
J Exp Child Psychol 2018 Dec 11;179:212-226. Epub 2018 Dec 11.
Institute of Education, ELTE Eötvös Loránd University, 1053 Budapest, Hungary; Department of Language, Literature and Communication, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, the Netherlands; Faculty of Arts and Education, University of Stavanger, 4036 Stavanger, Norway.
Experiments with film-like story presentations have been found to be beneficial in supporting children's story comprehension and word learning. The main goal of the current study was to disentangle the effects of visual and auditory enhancements in digital books. Participants were 99 typically developing children (41 boys and 58 girls) aged 4-6 years from two public kindergartens in Bursa, Turkey. Read More
Neurobiol Aging 2018 Nov 17;75:54-61. Epub 2018 Nov 17.
School of Psychology, Cardiff University, Cardiff, UK. Electronic address:
The anterior thalamic nuclei are important for spatial and episodic memory, however, surprisingly little is known about the status of these nuclei in neurological conditions that present with memory impairments, such as Down syndrome. We quantified neurons and glial cells in the anterior thalamic nuclei of four older patients with Down syndrome. There was a striking reduction in the volume of the anterior thalamic nuclei and this appeared to reflect the loss of approximately 70% of neurons. Read More
Sci Total Environ 2018 Nov 28;657:498-508. Epub 2018 Nov 28.
Sichuan Climate Centre, Chengdu 610071, China.
The alpine wetlands on the Tibetan Plateau (TP) are ecosystems vulnerable to global climate change. It has been recognized that future climate change may have a significant impact on methane (CH) emissions from the plateau, while less attention has been paid to predicting temporal and spatial variations in CH emissions from TP natural wetlands. In this study, we used an integrated model framework based on the CH4MOD, TOPMODEL and TEM models to predict CH emissions from potential natural wetlands on the TP under IPCC AR5 scenarios from 2006 to 2100. Read More
Water Res 2018 Nov 30;150:358-367. Epub 2018 Nov 30.
School of Environment, Beijing Normal University, No. 19, Xinjiekouwai Street, Beijing, 100875, China; Department of Environmental Health and Engineering, Bloomberg School of Public Health, The John Hopkins University, 615 North Wolfe Street, MD, 21205, USA. Electronic address:
Silica scaling of reverse osmosis membranes in brackish water desalination is less understood than hardness scaling due to the complex silica behaviors at the membrane/water interface. In this study, -COOH, -SOH, -NH and -OH functional groups were introduced onto polyamide membranes to create distinct surface physicochemical properties. The resulting membranes were further studied under similar scaling conditions to yield temporal flux loss data that were empirically interpreted by a logistic growth model. Read More
Hum Pathol 2018 Dec 11. Epub 2018 Dec 11.
Department of Pathology, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Republic of Korea; Institute of Neuroscience, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:
Multinodular and vacuolating neuronal tumor (MVNT) of the cerebrum is a recently recognized rare neuronal tumor, and its pathogenesis is unclear. We analyzed 7 cases of histologically typical MVNT: six were adults [mean age: 43.0years (range: 23-56)] and one was a child (10-year-old). Read More
Annu Rev Clin Psychol 2018 Dec 14. Epub 2018 Dec 14.
Department of Clinical, Neuro-, and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, 1081 BT Amsterdam, The Netherlands; email:
Psychotherapies may work through techniques that are specific to each therapy or through factors that all therapies have in common. Proponents of the common factors model often point to meta-analyses of comparative outcome studies that show all therapies have comparable effects. However, not all meta-analyses support the common factors model; the included studies often have several methodological problems; and there are alternative explanations for finding comparable outcomes. Read More
J Am Chem Soc 2018 Dec 14. Epub 2018 Dec 14.
Super-resolution fluorescence microscopy is a powerful tool to visualize biomolecules and cellular structures at the nanometer scale. Employing these techniques in living cells has opened up the possibility to study dynamic processes with unprecedented spatial and temporal resolution. Different physical approaches to super-resolution microscopy have been introduced over the last years. Read More
PLoS One 2018 14;13(12):e0207717. Epub 2018 Dec 14.
University of Central Florida, Orlando, Florida, United States of America.
We determined the number of permits for oil and gas activities in 14 coastal Louisiana parishes from 1900 to 2017, compared them to land loss on this coast, and estimated their restoration potential. A total of 76,247 oil and gas recovery wells were permitted, of which 35,163 (46%) were on land (as of 2010) and 27,483 of which are officially abandoned. There is a direct spatial and temporal relationship between the number of these permits and land loss, attributable to the above and belowground changes in hydrology resulting from the dredged material levees placed parallel to the canal (spoil banks). Read More
PLoS One 2018 14;13(12):e0209015. Epub 2018 Dec 14.
Division of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, United States of America.
Patellofemoral pain (PFP) is one of the most common overuse injuries of the knee. Previous research has found that individuals with PFP exhibit differences in peak hip kinematics; however, differences in peak knee kinematics, where the pain originates, are difficult to elucidate. To better understand the mechanism behind PFP, we sought to characterize differences in knee gait kinematic waveform patterns in individuals with PFP compared to healthy individuals using fast Fourier transform (FFT). Read More
PLoS One 2018 14;13(12):e0208988. Epub 2018 Dec 14.
Department of General Psychology, Justus-Liebig University, Giessen, Germany.
Although the natural haptic perception of textures includes active finger movements, it is unclear how closely perception and movements are linked. Here we investigated this question using oriented textures. Textures that are composed of periodically repeating grooves have a clear orientation defined by the grooves. Read More
PLoS One 2018 14;13(12):e0209382. Epub 2018 Dec 14.
Neurorehabilitation Research Center, Kio University, Nara, Japan.
Mechanical and electrical noise stimulation to the body is known to improve the sensorimotor system. This improvement is related to stochastic resonance (SR), a phenomenon described as a "noise benefit" to various sensory and motor systems. The current study investigated the influence of SR on visuomotor temporal integration and hand motor function under delayed visual feedback in healthy young adults. Read More
PLoS One 2018 14;13(12):e0208010. Epub 2018 Dec 14.
Commonwealth Scientific and Industrial Research Organization (CSIRO), Canberra, Australia.
Trichodesmium, a filamentous bloom-forming marine cyanobacterium, plays a key role in the biogeochemistry of oligotrophic ocean regions because of the ability to fix nitrogen. Naturally occurring in the Great Barrier Reef (GBR), the contribution of Trichodesmium to the nutrient budget may be of the same order as that entering the system via catchment runoff. However, the cyclicity of Trichodesmium in the GBR is poorly understood and sparsely documented because of the lack of sufficient observations. Read More
Chem Rev 2018 Dec 14. Epub 2018 Dec 14.
University of California , San Diego, 9500 Gilman Drive, BRFII , La Jolla , CA 92093-0702 , United States.
Cellular signaling networks are the foundation which determines the fate and function of cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over 25 years ago enabled the development of a diverse array of genetically encodable fluorescent biosensors that are capable of measuring the spatiotemporal dynamics of signal transduction pathways in live cells. In an effort to encapsulate the breadth over which fluorescent biosensors have expanded, we endeavored to assemble a comprehensive list of published engineered biosensors, and we discuss many of the molecular designs utilized in their development. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1097-1101
Children's National Medical Center, Department of Otolaryngology, Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, Beijing,100045, China.
To summarize the clinical characteristics and clinical treatment of congenital cholesteatoma (CC) of the middle ear in children, provide early diagnosis methods and explore standardized diagnosis and treatment plan.A retrospective chart review of 94 patients with a diagnosis of middle ear cholesteatoma, in Beijing Children's Hospital, between 2009 and 2015 was carried on. 14 patients with CC were identified using the criteria proposed by Levenson, and were divided into two groups according to the course of disease. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1082-1085;1090
Department of Radiology, Southern Medical University Nanfang Hospital.
Application of technique of high resolution CT (HRCT) and multipliate plane reconstruction, analyzed the image features of suspicious superior semicircular canal dehiscence (SSCD) to improve the understanding of the SSCD.From January 2016 to April 2017, a total of 230 adult patients who checked temporal bone HRCT were collected in this retrospective study, of which 160 cases (320 ears) of the non-SSCD, 73 cases were male (146 ears), 87 cases were female (174 ears), aged 18 to 70 years old; 70 cases (113 ears) were suspicious diagnosed with SSCD, 33 cases were male (55 ears), 37 cases were female (58 ears), and 18 to 71 years old. The thin section CT scan of the temporal bone translocation was performed on all subjects, then the CT post processing workstation was used for multipliate plane reconstruction (MPR), and the main rows of coronal and oblique sagittal image reconstruction was performed. Read More
Korean J Ophthalmol 2018 Dec;32(6):459-469
Division of Rheumatology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Purpose: To evaluate changes in the peripapillary retinal nerve fiber layer (RNFL) thicknesses using spectral-domain optical coherence tomography (SD-OCT) in hydroxychloroquine (HCQ) users.
Methods: The medical records of HCQ users were retrospectively reviewed. In these HCQ users, an automated perimetry, fundus autofluorescence photography, and SD-OCT with peripapillary RNFL thickness measurements were performed. Read More
Risk Anal 2018 Dec 14. Epub 2018 Dec 14.
Department of Civil and Urban Engineering, Connected Cities for Smart Mobility towards Accessible and Resilient Transportation (C2SMART) Center, and Center for Urban Science and Progress (CUSP), New York University, Brooklyn, NY, USA.
The widely used empirical Bayes (EB) and full Bayes (FB) methods for before-after safety assessment are sometimes limited because of the extensive data needs from additional reference sites. To address this issue, this study proposes a novel before-after safety evaluation methodology based on survival analysis and longitudinal data as an alternative to the EB/FB method. A Bayesian survival analysis (SARE) model with a random effect term to address the unobserved heterogeneity across sites is developed. Read More
BJU Int 2018 Dec 14. Epub 2018 Dec 14.
Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Objectives: To create a rat model for neurogenic detrusor underactivity (DU) by bilateral pelvic nerve crush injury (BPNI) and to study temporal changes in detrusor contractility and morphology.
Methods: Male Sprague-Dawley rats were subjected to BPNI or sham surgery and evaluated 1, 3 and 9 weeks after surgery. Bladder function was determined in vivo by awake cystometry, micturition pattern analysis and 24-hours urine collection. Read More
Brain Behav 2018 Dec 14:e01180. Epub 2018 Dec 14.
Department of Neurology, Xinxiang Medical University, Xinxiang, China.
Objective: Alzheimer's disease (AD) is the most common form of dementia characterized by memory loss at disease onset. The gene mutations in the amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2) are the frequent causes of AD. However, the clinical and genetic features of AD overlap with other neurodegenerative diseases. Read More