333 results match your criteria Telogen Effluvium


Oral minoxidil treatment for hair loss: A review of efficacy and safety.

J Am Acad Dermatol 2020 Jul 1. Epub 2020 Jul 1.

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine. Electronic address:

Background: Although topical minoxidil is an effective treatment option for hair loss, many patients are poorly compliant due to the necessity to apply the medication twice a day, undesirable hair texture, and scalp irritation.

Objective: In recent years, oral minoxidil at low dose has been proposed as a safe alternative. This study reviewed articles in which oral minoxidil was utilized to treat hair loss to determine its efficacy and safety as an alternative to topical minoxidil. Read More

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http://dx.doi.org/10.1016/j.jaad.2020.06.1009DOI Listing

Telogen Effluvium: A Review of the Literature.

Cureus 2020 May 27;12(5):e8320. Epub 2020 May 27.

Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, PAK.

Telogen effluvium is one of the most common causes of alopecia. It is a scalp disorder characterized by excessive shedding of hair. Several factors such as drugs, trauma, and emotional and physiological stress can lead to the development of telogen effluvium. Read More

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http://dx.doi.org/10.7759/cureus.8320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320655PMC

Evaluation of the effects of COVID-19 pandemic on hair diseases through a web-based questionnaire.

Dermatol Ther 2020 Jun 28:e13923. Epub 2020 Jun 28.

Department of Biostatistics and Medical Informatics, Medical Faculty, Inonu University, Malatya, Turkey.

Aim: Current quarantine conditions are a difficult process for individuals and can worsen the psychological state. Increased psychosocial stress can affect the course of many common "stress-sensitive" skin conditions. This study examined the possible effects of COVID-19 on hair and scalp diseases such as telogen effluvium (TE), alopecia areata (AA), and seborrheic dermatitis (SD) in individuals who had to stay at home for a long time and the patients' methods of dealing with these diseases. Read More

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http://dx.doi.org/10.1111/dth.13923DOI Listing

Study of serum vitamin D levels in men with premature androgenetic alopecia.

Int J Dermatol 2020 Jun 9. Epub 2020 Jun 9.

Department of Biochemistry, Lady Hardinge Medical College, New Delhi, India.

Background: Vitamin D deficiency had been associated with various hair loss disorders, such as telogen effluvium, alopecia areata, and female pattern hair loss. However, previous studies have not found a correlation between serum vitamin D levels and the severity of androgenetic alopecia.

Methods: A case-control study was conducted for a period of one year in a public tertiary care hospital. Read More

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http://dx.doi.org/10.1111/ijd.14982DOI Listing
June 2020
1.227 Impact Factor

Low-dose oral minoxidil as treatment for non-scarring alopecia: a systematic review.

Int J Dermatol 2020 Jun 9. Epub 2020 Jun 9.

Department of Dermatology, University of California, Irvine, Irvine, CA, USA.

Background: Topical minoxidil has been used for almost 40 years to treat alopecia. There is growing evidence supporting off-label use of low-dose oral minoxidil.

Objective: To conduct a systematic review evaluating the use of oral minoxidil for all types of alopecia. Read More

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http://dx.doi.org/10.1111/ijd.14933DOI Listing
June 2020
1.227 Impact Factor

Ischemia-modified albumin as a possible marker of oxidative stress in patients with telogen effluvium.

An Bras Dermatol 2020 Jul - Aug;95(4):447-451. Epub 2020 May 6.

Department of Biochemistry, Ataturk Training and Research Hospital, Ankara, Turkey.

Background: Telogen effluvium is the most common form of non-scarring alopecia characterized by diffuse hair loss. Ischemia-modified albumin is a marker of oxidative stress and inflammation.

Objective: The aim of this study was to compare the levels of ischemia-modified albumin of telogen effluvium patients with healthy controls. Read More

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http://dx.doi.org/10.1016/j.abd.2020.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335859PMC
May 2020
0.866 Impact Factor

Management of telogen effluvium during the COVID-19 emergency: Psychological implications.

Dermatol Ther 2020 May 22:e13648. Epub 2020 May 22.

Department of Clinical-Surgical, Diagnostic and Pediatric Science, Institute of Dermatology, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1111/dth.13648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267137PMC

Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern Hair Loss and Telogen Effluvium.

Dermatol Res Pract 2020 5;2020:8125081. Epub 2020 May 5.

Moscow Scientific and Practical Centre of Clinical and Aesthetic Dermatology and Venerology, Moscow City Health Department, Moscow, Russia.

Follicular proteoglycans are key players with structural, functional, and regulatory roles in the growth and cycling behaviour of the hair follicles. The expression pattern of specific proteoglycans is strongly correlated with follicular phase transitions, which further affirms their functional involvement. Research shows that bioactive proteoglycans, e. Read More

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http://dx.doi.org/10.1155/2020/8125081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222612PMC

Biotin Deficiency in Telogen Effluvium: Fact or Fiction?

J Clin Aesthet Dermatol 2020 Mar 1;13(3):37-40. Epub 2020 Mar 1.

All authors are with the Faculty of Medicine at Benha University in Benha, Egypt.

Biotin is popular in hair loss treatment supplements, although the frequency of its deficiency in patients with hair loss has not been established. This work sought to assess the serum levels of biotin in patients with telogen effluvium. This case-control study included 60 patients with telogen effluvium and 20 control subjects. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159307PMC

The Role of Diet as an Adjuvant Treatment in Scarring and Nonscarring Alopecia.

Skin Appendage Disord 2020 Mar 7;6(2):88-96. Epub 2020 Jan 7.

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, Florida, USA.

Background: Diet is known to affect a wide range of health disorders. Many patients with hair and scalp diseases often inquire about special diets that may improve their symptoms.

Objective: To evaluate nutrition and diet as adjunct treatments in nonscarring and scarring alopecia. Read More

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http://dx.doi.org/10.1159/000504786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109385PMC

Oral isotretinoin combined with topical clobetasol 0.05% and tacrolimus 0.1% for the treatment of frontal fibrosing alopecia: a randomized controlled trial.

J Dermatolog Treat 2020 Apr 20:1-7. Epub 2020 Apr 20.

Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Frontal fibrosing alopecia (FFA) is a scarring alopecia with no promising treatment. To evaluate the additive efficacy of oral isotretinoin to topical treatments. Between November 2017 and August 2018, FFA patients were randomly assigned to receive either isotretinoin (20 mg/d) plus topical treatments (clobetasol 0. Read More

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http://dx.doi.org/10.1080/09546634.2020.1750553DOI Listing
April 2020
1.764 Impact Factor

Relationship between helicobacter pylori infection and pityriasis versicolor: Can helicobacter pylori infection be a new etiologic factor for pityriasis versicolor?

Turk J Med Sci 2020 Mar 10. Epub 2020 Mar 10.

Background/aim: H. pylori has been found to be related to certain dermatological diseases. However, there is no data as yet to propose an association between H. Read More

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http://dx.doi.org/10.3906/sag-1910-48DOI Listing

Efficacy and safety of a new formulation kit (shampoo + lotion) containing anti-inflammatory and antioxidant agents to treat hair loss.

Dermatol Ther 2020 May 20;33(3):e13293. Epub 2020 Mar 20.

Hypera Pharma, São Paulo, SP, Brazil.

Androgenetic alopecia (AGA) and telogen effluvium (TE) are common causes of hair loss, with limited options for treatment. The aim of this study was to determine the efficacy and safety of a new formulation kit (Pielus Anti-hair loss lotion and shampoo) containing anti-inflammatory and antioxidant agents in patients with TE and/or AGA. This was a prospective, single-arm, open-label study with 35 women and 10 men, median age of 44 years, with clinical diagnosis of TE and/or AGA. Read More

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http://dx.doi.org/10.1111/dth.13293DOI Listing

Risk Analysis of Lurasidone in Patients with Schizophrenia and Bipolar Depression.

CNS Neurol Disord Drug Targets 2020 ;19(2):109-114

Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Raebareli (NIPER-R), Lucknow (UP) -226002, India.

Lurasidone was approved by the United States Food and Drug Administration (FDA) for the treatment of schizophrenia, as well as for the treatment of bipolar depression. However, emerging reports have indicated various adverse drug reactions with the use of lurasidone. Thus, in this article, we have analyzed the risk profile of lurasidone in the established therapeutic indication. Read More

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http://dx.doi.org/10.2174/1871527319666200303120147DOI Listing
January 2020
2.628 Impact Factor

Types and Treatment of Hair Loss in Men and Women.

Authors:
Emma Coleman

Plast Surg Nurs 2020 Jan/Mar;40(1):6-19

Emma Coleman, RGN, is an aesthetic and dermatology registered general nurse, Kent, United Kingdom.

In this article, the author focuses on 4 common hair loss disorders that occur in both men and women. The author discusses research related to androgenetic alopecia, telogen effluvium, alopecia areata, and scarring alopecia and provides details on how to approach and manage these diseases according to patient gender. There are a range of tools and tests that can assist with the diagnostic process and help ensure that relevant and high standards of patient care are maintained. Read More

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http://dx.doi.org/10.1097/PSN.0000000000000285DOI Listing
February 2020

Increased Preauricular Wrinkles in Frontal Fibrosing Alopecia Compared to Age-Matched Controls: A Prospective Study of 64 Patients.

Skin Appendage Disord 2020 Jan 18;6(1):11-13. Epub 2019 Sep 18.

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

Introduction: Frontal fibrosing alopecia (FFA) is a scarring alopecia affecting mainly postmenopausal females. Associated clinical signs include facial papules, glabellar red dots, depression of frontal veins, and lichen planus pigmentosus. Our objective was to establish the validity of increased preauricular lines as another clinical marker of FFA. Read More

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http://dx.doi.org/10.1159/000502700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995943PMC
January 2020

Dilation of Multiple Eccrine Ducts as a Highly Specific Marker for Cicatricial Alopecia.

Am J Dermatopathol 2019 Dec;41(12):871-878

Assistant Professor, Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Background: Eccrine duct dilation (EDD) was recently described to occur more frequently in cicatricial alopecias than noncicatricial alopecias. Because single EDD can be useful in the evaluation of alopecias, we aimed to determine whether dilation of multiple eccrine duct units, or "multiple eccrine duct dilation (MEDD)," could more specifically discriminate between cicatricial and noncicatricial alopecias.

Methods: We retrospectively evaluated 611 scalp biopsies (342 cicatricial alopecias and 269 noncicatricial alopecias). Read More

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http://dx.doi.org/10.1097/DAD.0000000000001396DOI Listing
December 2019

Alopecia in Belgian Blue crossbred calves: a case series.

BMC Vet Res 2019 Nov 15;15(1):411. Epub 2019 Nov 15.

Institute of Veterinary Pathology at the Centre for Clinical Veterinary Medicine, Veterinary Faculty, Ludwig-Maximilians-Universität München, Veterinärstr. 13, 80539, Munich, Germany.

Background: Alopecia is defined as the partial or complete absence of hair from areas of the body where it normally grows. Alopecia secondary to an infectious disease or parasitic infestation is commonly seen in cattle. It can also have metabolic causes, for example in newborn calves after a disease event such as diarrhoea. Read More

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http://dx.doi.org/10.1186/s12917-019-2140-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858713PMC
November 2019

Telogen effluvium: a comprehensive review.

Authors:
Alfredo Rebora

Clin Cosmet Investig Dermatol 2019 21;12:583-590. Epub 2019 Aug 21.

University of Genoa, Genoa, Italy.

Excessive hair shedding is a common and alarming phenomenon, usually complained about by women. The disorder, named telogen effluvium (TE), bears several problems which are discussed in this essay. They are as follows: 1) how profuse a hair loss must be for TE to be diagnosed; 2) its heterogeneity that needs to be properly classified; 3) its distinction from androgenetic alopecia (AGA) with which it is often associated; 4) its main symptom, trichodynia, which is unclear how frequent and how diagnostic could be; 5) why histopathology has been reported to be nonspecific; and 6) its management, from diagnosis to treatment. Read More

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http://dx.doi.org/10.2147/CCID.S200471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709511PMC
August 2019
6 Reads

Telogen effluvium x female pattern hair loss: is there correlation?

An Bras Dermatol 2019;94(4):486-487. Epub 2019 Oct 17.

Medical Student, Universidade Federal do Paraná, Curitiba, PR, Brazil.

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http://dx.doi.org/10.1590/abd1806-4841.20198427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007028PMC
November 2019

Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study.

Clin Cosmet Investig Dermatol 2019 8;12:745-750. Epub 2019 Oct 8.

Department of Dermatology, Andrology and STDs, Faculty of Medicine, Menoufiya University, Menoufiya Governorate, Egypt.

Background: Telogen effluvium (TE) is a form of alopecia characterized by diffuse hair shedding. Vitamin D receptor (VDR) plays a role in hair cycle regulation as it is expressed in follicular keratinocytes and dermal papilla cells.

Purpose: To investigate the association between Cdx1 and Taq1 VDR gene polymorphisms and chronic TE. Read More

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http://dx.doi.org/10.2147/CCID.S227232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790134PMC
October 2019
1 Read

Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study.

Skin Appendage Disord 2019 Aug 2;5(5):309-315. Epub 2019 Apr 2.

Department of Dermatology and Cutaneous Surgery, University of Miami L. Miller School of Medicine, Miami, Florida, USA.

Background: The frequency of different types of alopecia is not clearly reported in recent studies.

Objective: To analyze the frequency of the types of alopecia in patients consulting at specialist hair clinics (SHC) and to assess for global variations.

Methods: Multicenter retrospective study including data from patients evaluated at referral SHC in Europe, America, Africa and Australia. Read More

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http://dx.doi.org/10.1159/000496708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751437PMC
August 2019
2 Reads

Overnight Alopecia: A Subtype of Acute Diffuse and Total Alopecia?

Int J Trichology 2019 Jul-Aug;11(4):170-172

Cutis Academy of Cutaneous Sciences (Affiliated to Rajiv Gandhi University of Health Sciences), Bengaluru, Karnataka, India.

Acute diffuse and total alopecia (ADTA) is a variant of alopecia areata which lacks the typical patchy hair loss seen in classical alopecia areata and presents with an acute onset of diffuse hair loss commonly reported in young females with the duration from disease onset to diffuse hair loss ranging from 2 to 20 weeks. Although the clinical features of ADTA resemble telogen effluvium, dermoscopy can prove to be a useful tool for differentiating these two conditions and avoiding unnecessary investigations as specific dermoscopic findings of alopecia areata are invariably present along the disease course. Herein, we report a case of ADTA in a 42-year-old Indian female who presented with sudden onset of diffuse hair loss of only 1-day duration. Read More

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http://dx.doi.org/10.4103/ijt.ijt_36_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706982PMC
September 2019
5 Reads

A Clinico-Epidemiological Study of Scalp Hair Loss in Children (0-18 Years) in Kota Region, South-East Rajasthan.

Indian J Dermatol 2019 Jul-Aug;64(4):285-291

Department of Dermatology, Venereology and Leprology, Government Medical College, Kota, Rajasthan, India.

Background: Currently, the studies related to hair loss in children showed the variable prevalence of different clinical patterns and causes of scalp hair loss, that had regional variation.

Aims: The aim of this study is to evaluate the epidemiology and clinical pattern of scalp hair loss in children (0-18 years age group).

Materials And Methods: A total of 300 children presenting with scalp hair loss were studied during a period of 1 year from April 2015 to March 2016. Read More

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http://dx.doi.org/10.4103/ijd.IJD_393_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714197PMC
September 2019
5 Reads

Expert consensus on the management of Telogen Effluvium in India.

Int J Trichology 2019 May-Jun;11(3):107-112

Derma Skin Cosmetic and Laser Clinic, Nagpur, Maharashtra, India.

Alopecia, a frequently reported problem, severely impacts the quality of life of patients and is often associated with loss of confidence and low self-esteem. Several conditions such as telogen effluvium (TE), anagen effluvium, diffuse type of alopecia areata, female pattern hair loss, hair shaft abnormalities, loose anagen hair syndrome, and congenital atrichia or hypotrichosis are associated with hair loss. The actual prevalence rate of TE is not reported since most cases are subclinical in nature. Read More

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http://dx.doi.org/10.4103/ijt.ijt_23_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580807PMC
July 2019
4 Reads

Imiquimod-induced effluvium after intravaginal application for treatment of cervical intraepithelial neoplasia.

JAAD Case Rep 2019 Jul 26;5(7):602-604. Epub 2019 Jun 26.

University Department of Dermatology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.jdcr.2019.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610626PMC
July 2019
5 Reads

Preliminary results of the use of scalp microneedling in different types of alopecia.

J Cosmet Dermatol 2020 Mar 29;19(3):646-650. Epub 2019 Jun 29.

Department of Experimental, Diagnostic and Specialty Medicine-Division of Dermatology, University of Bologna, Bologna, Italy.

Background: Androgenetic alopecia (AGA) is the result of progressive patterned hair density reduction and sometimes can be associated with telogen effluvium (TE). The efficacy of conventional therapy is variable, and therefore, there is a need for adjuvant and newer modalities of treatment in order to give faster and better outcomes. Microneedling has been reported to be a promising, effective, and safe new technique in the treatment of AGA. Read More

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http://dx.doi.org/10.1111/jocd.13061DOI Listing
March 2020
6 Reads

Common causes of paediatric alopecia

Aust J Gen Pract 2018 10;47(10):692-696

MBBS, MD, FACD, Director, Sinclair Dermatology, East Melbourne, Vic.

Background: Hair loss in children aged 12 years and younger is most often due to a benign or self-limiting condition. This article presents a review of the assessment of common causes of paediatric alopecia and outlines the implications for general practice.

Objective: The objective of this article is to help readers systematically assess a child presenting with alopecia, manage the most common diseases of paediatric alopecia and identify patients requiring referral to a dermatologist. Read More

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http://dx.doi.org/10.31128/AJGP-11-17-4416DOI Listing
October 2018
11 Reads

"Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women".

J Cosmet Dermatol 2020 Feb 28;19(2):485-493. Epub 2019 May 28.

Robertet Group, Grasse, France.

Background: Miliacin, the main triterpenoid from millet, is known to stimulate keratinocyte metabolism and proliferation. Polar lipids are able to form vesicles with active compounds and to improve their bioavailability.

Objectives: We aimed to demonstrate potential benefits of a solution of miliacin encapsulated within polar lipids (MePL) on telogen effluvium prevention and hair condition in women. Read More

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http://dx.doi.org/10.1111/jocd.12998DOI Listing
February 2020
9 Reads

Scalp biopsy identifies systemic amyloidosis presenting as isolated telogen effluvium: A case report.

SAGE Open Med Case Rep 2019 2;7:2050313X19847783. Epub 2019 May 2.

Department of Dermatology & Skin Science, The University of British Columbia, Vancouver, BC, Canada.

AL amyloidosis is a complication of B-cell dyscrasias and multiple myeloma, manifest as deposition of antibody fragments in many different organs, including the skin. We describe a rare case of this systemic disease which presented with isolated scalp alopecia. Further investigation led to the diagnosis of an occult plasma-cell dyscrasia, showing the benefit of including systemic amyloidosis in the differential diagnosis of alopecia. Read More

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http://dx.doi.org/10.1177/2050313X19847783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501649PMC
May 2019
5 Reads

Alopecia in Cronkhite-Canada syndrome: Is it truly telogen effluvium?

Australas J Dermatol 2019 Nov 6;60(4):e342-e343. Epub 2019 May 6.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/ajd.13073DOI Listing
November 2019
8 Reads

The use of phosphodiesterase inhibitors for the treatment of alopecia.

J Dermatolog Treat 2020 May 2;31(3):245-253. Epub 2019 Apr 2.

Department of Dermatology, University of California Irvine, Irvine, CA, USA.

Hair loss encompasses a group of scarring and nonscarring diseases with limited treatment options. Understanding the pathogenesis of alopecias has led to the experimental use of phosphodiesterase inhibitors (PDEi). To perform a systematic review of literature surrounding the use of PDEi for alopecia. Read More

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http://dx.doi.org/10.1080/09546634.2019.1592097DOI Listing
May 2020
22 Reads

The role of photobiomodulation when associated with microneedling in female pattern hair loss: A randomized, double blind, parallel group, three arm, clinical study protocol.

Medicine (Baltimore) 2019 Mar;98(12):e14938

Biophotonics Applied to Health Sciences Postgraduation Program, Universidade Nove de Julho, Universidade Nove de Julho.

The female hair loss pattern was originally described as a synonym for androgenetic alopecia. It has been defined as progressive miniaturizations of the hair follicles, with a great impact on the quality of life of affected patients, causing significant psychosocial limitations. It was recently proven that photobiomodulation is a safe and effective way to treat the different types of hair loss. Read More

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http://dx.doi.org/10.1097/MD.0000000000014938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709013PMC
March 2019
24 Reads

Beau lines and telogen effluvium following aluminium phosphide poisoning.

N Z Med J 2019 03 8;132(1491):90-92. Epub 2019 Mar 8.

Rocky Mountain Poison and Drug Center, Denver, CO, USA

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March 2019
6 Reads

The influence of methotrexate on hair loss while using immunomodulatory doses.

Pol Merkur Lekarski 2019 Feb;46(272):77-79

Department of Dermatology, University Hospital in Cracow, Poland.

Hair loss is a significant and constantly growing social problem among both women and men. Many drugs through their toxic effects on the cells of the hair follicle matrix have an influence on mitotic divisions and the hair growth cycle, leading to anagen or telogen effluvium. Currently, there are more and more publications and clinical studies evaluating the possibility of using methotrexate in the treatment of various types of non-scarring and scarring alopecia, but there is no study of the effect relating to the hair loss with low doses of the drug in other therapeutic indications. Read More

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February 2019
37 Reads

Research on the Balance of Thiol-Disulfide in Blood Serum in Women with Telogen Effluvium.

Int J Trichology 2019 Jan-Feb;11(1):20-25

Department of Biochemistry, Atatürk Training and Research Hospital, Ankara, Turkey.

Backgrounds: Telogen effluvium (TE) is the most common reason for hair loss in humans. Although the exact etiopathogenesis of TE has not been revealed clearly and completely, multifactorial etiologies are to be blamed. In recent years, since oxidative stress (OS) has been shown to play an important role in the etiopathogenesis of so many diseases, the effects of OS on several skin diseases are researched and analyzed. Read More

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http://dx.doi.org/10.4103/ijt.ijt_78_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385515PMC
March 2019
10 Reads

Non-scarring Alopecias in Iranian Patients: A Histopathological Study With Hair Counts.

Iran J Pathol 2018 12;13(3):317-324. Epub 2018 Sep 12.

Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background And Objective: Non-scarring alopecia is a challenge in the diagnosis and treatment, rarely studied in Asian countries.The current study aimed at evaluating histopathological features including hair count of different subtypes of non-scarring alopecia in Iranian patients.

Methods: The current study was conducted on 114 cases diagnosed with non-scarring alopecia in Molecular Dermatology Research Center and Pathology Department of Shiraz University of Medical Sciences, Shiraz, Iran. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322526PMC
September 2018
37 Reads

New pattern hair loss in young Turkish women; What's wrong in their daily life?

Skin Res Technol 2019 May 5;25(3):367-374. Epub 2019 Jan 5.

Department of Dermatology, Yildirim Beyazit University School of Medicine, Ankara, Turkey.

Background: The application of heat, used to straighten the typically coiled hair, has long been hypothesized to play a role in the etiologic factor for central centrifugal cicatricial alopecia (CCCA). The aim of this study was to evaluate the effect of thermal hair straightening on hair loss pattern in Asian women exist.

Materials And Methods: Thirty-five patients with hair loss who have been using hair straightening devices and 25 patients with telogen effluvium were enrolled in this prospective study. Read More

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http://dx.doi.org/10.1111/srt.12662DOI Listing
May 2019
36 Reads

Off-Label Use of Topical Minoxidil in Alopecia: A Review.

Am J Clin Dermatol 2019 Apr;20(2):237-250

Department of Dermatology, Northwestern University, 676 N St Clair St, Suite 1600, Chicago, IL, 60611, USA.

Topical minoxidil is a well-known and often-utilized drug in dermatological practice for the treatment of alopecia. It was approved by the United States Food and Drug Administration for the treatment of androgenetic alopecia in 1988. Since its approval, minoxidil has been used off-label for the treatment of many other types of alopecia, with minimal formal evidence of efficacy. Read More

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http://link.springer.com/10.1007/s40257-018-0409-y
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http://dx.doi.org/10.1007/s40257-018-0409-yDOI Listing
April 2019
21 Reads

Telogen Effluvium With Dysesthesia (TED) Has Lower B12 Levels and May Respond to B12 Supplementation

J Drugs Dermatol 2018 11;17(11):1236-1240

We investigated a subtype of Telogen Effluvium associated with Dysesthesia, (TED) which was defined as the presence of Telogen Effluvium with severe itch, pain, soreness, burning, or formication in the absence of any inflammatory scalp disorder or medication associated with Telogen Effluvium or Dysesthesia. These are patients who present with a “burning” scalp or other dysesthesia associated with increased telogen hair shedding. Telogen Effluvium is not typically associated with any scalp symptoms. Read More

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November 2018
37 Reads

Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes.

J Photochem Photobiol B 2018 Dec 17;189:318-325. Epub 2018 Sep 17.

Merz Pharmaceuticals GmbH, Alfred-Wegener-Straße 2, 60438 Frankfurt, Germany. Electronic address:

Background: Ultraviolet radiation (UVR) is known to be harmful to normal human epidermal keratinocytes (NHEKs) of the epidermal skin layer, as well as to hair-follicle-associated keratinocytes. An oral formulation containing l-cystine, thiamin, calcium d-pantothenate, medicinal yeast, keratin and p-aminobenzoic acid (Panto[vi]gar®) has demonstrated clinical efficacy for the treatment of diffuse telogen effluvium; however, its mode of action at the cellular level, and in particular whether protective mechanisms are involved, has yet to be elucidated.

Objectives: To assess the capacity of ingredients of this oral formulation, both separately and in combination, to modulate the effects of UVR in growth-limited NHEKs in vitro. Read More

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http://dx.doi.org/10.1016/j.jphotobiol.2018.09.005DOI Listing
December 2018
30 Reads

Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort.

Antimicrob Agents Chemother 2019 02 29;63(2). Epub 2019 Jan 29.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.

Fluconazole-induced alopecia is a significant problem for patients receiving long-term therapy. We evaluated the hair cycle changes of fluconazole in a rat model and investigated potential molecular mechanisms. Plasma and tissue levels of retinoic acid were not found to be causal. Read More

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http://aac.asm.org/lookup/doi/10.1128/AAC.01384-18
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http://dx.doi.org/10.1128/AAC.01384-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355562PMC
February 2019
20 Reads

Alopecias in lupus erythematosus.

Lupus Sci Med 2018 25;5(1):e000291. Epub 2018 Oct 25.

Corporal Michael J Crescenz VAMC, Philadelphia, Pennsylvania, USA.

Several patterns of hair loss can occur in lupus erythematosus (LE). Alopecias which show histological characteristics of LE are LE-specific, and include discoid LE (DLE), diffuse or patchy hair loss in acute LE, subacute cutaneous LE, and rarely tumid LE. Lupus hair in SLE is a poorly characterised entity and may be a form of telogen effluvium. Read More

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http://dx.doi.org/10.1136/lupus-2018-000291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203010PMC
October 2018
13 Reads

HrQoL in hair loss-affected patients with alopecia areata, androgenetic alopecia and telogen effluvium: the role of personality traits and psychosocial anxiety.

J Eur Acad Dermatol Venereol 2019 Mar 2;33(3):608-611. Epub 2018 Dec 2.

Department of Experimental, Diagnostic and Speciality Medicine (DIMES), Alma Mater Studiorum Università di Bologna, Bologna, Italy.

Background: Illness impact on HrQoL has been widely studied in hair loss-affected patients, yet no study has addressed whether individual differences modulate HrQoL in patients with alopecia areata (AA), androgenetic alopecia (AGA) and telogen effluvium (TE).

Objective: To identify the personality dimensions most predictive of the impact of disease on HrQoL.

Method: A single-site cross-sectional study was carried out in the Dermatology Unit of Sant'Orsola-Malpighi Hospital, Bologna between September 2016 and September 2017. Read More

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http://dx.doi.org/10.1111/jdv.15327DOI Listing
March 2019
19 Reads

Effects of isotretinoin on the hair cycle.

J Cosmet Dermatol 2019 Apr 23;18(2):647-651. Epub 2018 Oct 23.

Department of Dermatology, Self-employed, Konya, Turkey.

Background/ Objectives: Isotretinoin is a synthetic vitamin A agent that affects all of the pathogenic factors that suppress sebum production and play a role in the formation of acne. It is frequently used in the treatment of moderate-severe acne vulgaris. However, there are some mucocutaneous and systemic side effects that limit the use of isotretinoin. Read More

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http://dx.doi.org/10.1111/jocd.12800DOI Listing
April 2019
9 Reads

Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time.

Exp Dermatol 2020 Mar 5;29(3):223-230. Epub 2018 Dec 5.

Department of Dermatology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

Background: Diffuse alopecia areata (DAA) often leads to a complete hair shedding within a few months.

Objective: To explore features and mechanisms underlying DAA.

Materials And Methods: Scalp and hair root dermoscopy were conducted on 23 DAA patients throughout the disease process, 20 patchy Alopecia areata patients, 23 acute telogen effluvium (ATE) patients and 10 normal controls. Read More

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http://doi.wiley.com/10.1111/exd.13799
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http://dx.doi.org/10.1111/exd.13799DOI Listing
March 2020
12 Reads

Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia.

Med Arch 2018 Apr;72(2):136-140

Biota Laboratories, R&D Center, Sancaktepe, Istanbul, Turkey.

Background: Currently while, topical minoxidil and oral finasteride are the only medications approved in androgenetic alopecia (AGA), the cause oriented treatment and immunsupressive treatment are being performed in telogen effluvium (TE) and alopecia areata (AA) respectively. Considering the inflammatory factors in the pathogenesis of these three nonscarring alopecia forms, we have formulated a mixture for topical usage composed of six different herbal extracts (HE) which have already known antiinflammatory and antioxidant features.

Materials And Methods: In addition to performing the phytochemical analysis of HE, we detected the gene expression level of IL-1α, the crucial hair loss mediator, for the putative efficacy in nonscarring alopecia. Read More

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http://www.ejmanager.com/fulltextpdf.php?mno=295214
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http://dx.doi.org/10.5455/medarh.2018.72.136-140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126931PMC
April 2018
16 Reads

Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.

Clin Cosmet Investig Dermatol 2018 10;11:431-436. Epub 2018 Sep 10.

Clinical Research, Farmoquímica S.A, Rio de Janeiro, Brazil.

Purpose: Telogen effluvium (TE) is defined as a diffuse hair loss characterized by shortening of the anagen phase and precipitation of the telogen phase, with a consequent reduction of total hair volume. Nutritional supplementation is indicated under conditions in which TE is related to dietary disorders. The aim of this clinical study was to compare the efficacy of two different supplements in monotherapy for TE. Read More

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https://www.dovepress.com/comparative-evaluation-between-two
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http://dx.doi.org/10.2147/CCID.S173082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136400PMC
September 2018
87 Reads

Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells.

Front Cell Infect Microbiol 2018 21;8:268. Epub 2018 Aug 21.

Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

During the epidemic of the dengue virus (DENV) infection in Taiwan in 2014 and 2015, we observed an abnormally high frequency of increased scalp hair shedding in infected individuals that could not be explained by telogen effluvium. In this study, the mechanism of hair loss caused by DENV was explored. Human hair follicle dermal papilla cells (HFDPCs) are essential for hair follicle morphogenesis and cycling. Read More

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http://dx.doi.org/10.3389/fcimb.2018.00268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110916PMC
August 2019
4 Reads