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Plast Reconstr Surg Glob Open 2022 Jun 20;10(6):e4423. Epub 2022 Jun 20.

Division of Plastic, Reconstructive & Aesthetic Surgery, National University Health System, Singapore.

Up to 36.7% of symptomatic COVID-19 patients will have telogen effluvium (TE), which refers to diffuse scalp alopecia. With the continuing global pandemic, a review of literature reports unpredictable and incomplete recovery with conventional treatment like minoxidil. Read More

J Eur Acad Dermatol Venereol 2022 Jun 20. Epub 2022 Jun 20.

Departamento de Dermatologia da FMB-Unesp, Botucatu, Brazil.

FP Essent 2022 Jun;517:11-16

Department of Dermatology - University of North Carolina School of Medicine, 410 Market St Suite 400, Chapel Hill, NC 27516.

Alopecia affects men and women and can result in significant distress for patients. Alopecias can be categorized as nonscarring or scarring. Nonscarring alopecias include male and female pattern alopecias, alopecia areata, telogen effluvium, traction alopecia, trichotillomania, and tinea capitis. Read More

Cureus 2022 Apr 28;14(4):e24573. Epub 2022 Apr 28.

Division of General Medicine, Department of Comprehensive Medicine 1, Saitama Medical Center, Jichi Medical University, Saitama, JPN.

Cases of subcutaneous abscess due to () infection are rare, even among immunocompromised patients. To our knowledge, there have only been eleven reports of such cases in adults, all of which presented with comorbidities of immunodeficiency, prior antibiotic administration, or skin breakdown following traumatic episodes or iatrogenic procedures. We report a rare case of a 42-year-old Japanese woman with a subcutaneous abscess due to  infection. Read More

Front Med (Lausanne) 2022 12;9:876561. Epub 2022 May 12.

Public Health Foundation, Dhaka, Bangladesh.

Introduction: Psychological stress from the ongoing coronavirus disease 2019 (COVID-19) pandemic can potentially aggravate the course of several stress-sensitive skin and hair diseases. This study aimed to determine the potential association of COVID-19 stress with hair diseases, such as telogen effluvium (TE), alopecia areata (AA), and seborrheic dermatitis (SD), among medical students in Bangladesh.

Methods: This online-based cross-sectional study was conducted among 404 medical students of Bangladesh using a self-administered questionnaire, including sociodemographic information, status of hair diseases (i. Read More

J Clin Aesthet Dermatol 2022 May;15(5):29-34

Dr K. Kaur is a junior resident at the Department of Dermatology Venereology & Leprosy at Sri Guru Ram Das Institute of Medical Sciences & Research in Amritsar, India.

Background: Female androgenetic alopecia (FAGA) is a patterned hair loss caused by progressive miniaturization of hair follicles. This leads to reduction in the number and thickness of hairs, especially in the central, frontal, and parietal scalp regions. Telogen effluvium (TE) is characterized by diffuse hair loss within months of a significant systemic stressor because of premature follicular transition from the anagen to the telogen. Read More

J Dermatol 2022 May 27. Epub 2022 May 27.

Clinical Development, Research and Development Headquarters Self-Medication, Taisho Pharmaceutical Co.Ltd, Tokyo, Japan.

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared a pandemic by the World Health Organization, and COVID-19 continues to have a major impact on society. Numerous studies have reported impaired health sequelae after COVID-19 recovery, one of which is hair loss. Individuals with hair loss experience a substantial mental burden, which potentially hinders their social life. Read More

Medicina (Kaunas) 2022 May 17;58(5). Epub 2022 May 17.

Department of Dermatology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

There is growing evidence that oxidative stress is involved in the pathogenesis of numerous conditions, including dermatological diseases. Various markers are available to assess oxidative stress, but none of these can be considered the ideal marker. Recent studies have shown that ischemia-modified albumin (IMA) is not only an indicator of ischemia, but also a marker of oxidative stress. Read More

Indian J Dermatol Venereol Leprol 2022 Apr 9:1-9. Epub 2022 Apr 9.

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University, Sohag, Egypt.

Background: Chronic telogen effluvium is characterised by diffuse loss of hair of the scalp. One of the emerging lines of treatment is platelet-rich plasma. However, not much of published data exist. Read More

JAAD Case Rep 2022 Jul 7;25:1-3. Epub 2022 May 7.

Department of Dermatology, University of California-Irvine, Irvine, California.

Int J Trichology 2022 Mar-Apr;14(2):49-54. Epub 2022 Apr 4.

Centre for Dermatology and Hair Diseases Professor Trüeb, Zurich-Wallisellen, Switzerland.

Background: The condition of the hair is closely related to the nutritional state. Normal supply, uptake, and transport of nutrients are of fundamental importance in tissues with a high biosynthetic activity such as the hair follicle.

Objective: The objective of the study was to evaluate the efficacy of a nutritional-based induction and maintenance treatment for telogen effluvium formulated with a combination of hydrolyzed collagen, amino acids, vitamins, and minerals. Read More

J Am Acad Dermatol 2022 May 5. Epub 2022 May 5.

Department of Dermatology, New York Medical College School of Medicine, Valhalla, NY, United States. Electronic address:

Int J Cosmet Sci 2022 May 6. Epub 2022 May 6.

Monasterium Laboratory, Münster, Germany.

Objectives: Hair loss and reduction in hair volume are hallmarks of hair disorders, such as telogen effluvium, or male or female pattern hair loss, and hair ageing, which can cause severe distress in both men and women. Common anti-hair loss drugs carry some side effects; therefore, novel, safer approaches targeting milder phenotypes are highly advocated. In this context, we investigated an extract of the alpine plant Edelweiss, Leontopodium alpinum var. Read More

JMIR Dermatol 2022 Apr-Jun;5(2):e37271. Epub 2022 Apr 27.

Department of Dermatology Icahn School of Medicine at Mount Sinai New York, NY United States.

Clin Cosmet Investig Dermatol 2022 22;15:735-743. Epub 2022 Apr 22.

Department of Physical and Rehabilitation Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Post-COVID-19 telogen effluvium has been largely reported as a sequela in the post-acute phase of COVID-19, causing major emotional distress among the affected patients. The affected individuals are further exposed to a vast amount of misinformation from the internet and social media and it is important for physicians to be familiar with the phenomenon and provide appropriate counselling to their patients regarding this condition. This article aims to review the evidence-based complementary strategies that can help enhance hair regrowth after post-COVID-19 hair loss, from psychological support and patient education to the importance of optimal nutrition and potential indications and benefits of oral nutritional supplementation, as well as the role of both topical and injectable hair growth stimulators. Read More

Dermatol Ther 2022 Apr 29:e15545. Epub 2022 Apr 29.

Dermatology & Venereology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

The clinical presentation of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2 COVID-19) varies from asymptomatic infection to a life-threatening, multiorgan disease. One of these manifestations is telogen effluvium (TE) which is characterized by diffuse hair loss occurring in patients previously infected with SARS-CoV-2 and lasts ~3 months, after which excessive hair loss follows. Hair follicles are known to contain a well-characterized niche for adult stem cells which is the bulge containing epithelial and melanocytic stem cells. Read More

J Am Acad Dermatol 2022 Apr 26. Epub 2022 Apr 26.

Dermatology Department, Trichology Unit, Ramon y Cajal University Hospital, Madrid, Spain; Trichology and Hair Transplantation Unit, Grupo Pedro Jaen Clinic, Madrid, Spain.

Einstein (Sao Paulo) 2022 25;20:eAO6320. Epub 2022 Mar 25.

Universidade Santo Amaro, São Paulo, SP, Brazil.

Objective: To analyze the pattern of triggering and exacerbation of dermatological diseases between March and July 2020 and to compare this pattern to the corresponding period of 2019.

Methods: This was a quantitative, descriptive, comparative and documentary study that was carried out through the retrospective analysis of medical records (March to July 2019 and 2020) of individuals assisted at a private dermatology practice service located in the southern area of the city of São Paulo (SP).

Results: We evaluated 992 medical consultations in 2019 and 1,176 in 2020. Read More

Ann Med 2022 12;54(1):869-874

Department of Cardiac-Thoracic-Vascular Sciences and Public Health, Respiratory Pathophysiology Unit, University of Padova, Padova, Italy.

A higher risk for COVID-19 infection and severity for men compared to women has been described since the beginning of the pandemic. The role of androgens has been recently highlighted as they control two key steps of coronavirus infection mediated through the transmembrane protease serin 2 (TMPRRS2) and the angiotensin-converting enzyme 2 (ACE2) receptor in the lung tissue. Furthermore, a high incidence of androgenic alopecia among males with COVID-19 disease have been reported. Read More

J Clin Med 2022 Feb 24;11(5). Epub 2022 Feb 24.

Department of Orthopedic Surgery, Ospedale di Gardone Val Trompia, 25063 Brescia, Italy.

Post-SARS-CoV-2 telogen effluvium has been described in case reports of COVID-19 patients. We evaluated the prevalence of post-SARS-CoV-2 telogen effluvium in patients from a single medical center, exploring any causal links with the infection. Our hospital-based, cross-sectional study was conducted with patient participants discharged with a diagnosis of SARS-CoV-2 pneumonia from 1 March to 4 April 2020. Read More

Dermatol Ther 2022 Jun 1;35(6):e15433. Epub 2022 Apr 1.

Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.

The prevalence of hair loss has increased during COVID-19. In this study, we review the current literature on incidence and characteristics of various types of COVID-19-related and COVID-19-vaccine- related hair loss including telogen effluvium, alopecia areata, friction alopecia and anagen effluvium. Regarding most of them, the more severe the infection, the more profound and prolonged the course of alopecia. Read More

Proc (Bayl Univ Med Cent) 2022 26;35(2):180-183. Epub 2022 Jan 26.

Veterans Affairs Medical Center, Brooklyn, New York.

Alopecia syphilitica (AS) is an uncommon manifestation of secondary syphilis, with a prevalence that ranges from 3% to 7%. It is a nonscarring alopecia that can present in a diffuse pattern, a moth-eaten pattern, or a mixed subtype. Due to its low prevalence and similar presentation to other forms of alopecia such as alopecia areata, telogen effluvium, and tinea capitis, dermatologists must maintain a high degree of suspicion for prompt diagnosis. Read More

Arch Dermatol Res 2022 Mar 4. Epub 2022 Mar 4.

Department of Dermatology, Wake Forest School of Medicine, 4618 Country Club Road, Winston-Salem, NC, 27104, USA.

While current studies have supported oral minoxidil as a novel, adjunctive therapy in non-scarring forms of alopecia, there continues to be limited data on oral minoxidil for these conditions. To assess oral minoxidil use in the treatment of androgenetic alopecia and telogen effluvium, a multi-center, retrospective analysis was conducted in 105 adult patients treated for androgenetic alopecia and/or telogen effluvium with oral minoxidil (dose range 0.625-2. Read More

JAAD Int 2022 Jun 22;7:67-77. Epub 2022 Feb 22.

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.

Background: COVID-19 is associated with androgenetic alopecia (AGA), telogen effluvium (TE), and alopecia areata (AA). No studies have analyzed the aggregate data to date.

Objective: We conducted a systematic review to characterize the types, incidence, timing, and clinical outcomes of COVID-19-associated alopecia. Read More

J Cosmet Dermatol 2022 May 28;21(5):1809-1815. Epub 2022 Feb 28.

Department of Dermatology and Venereology, Uşak University Training and Research Hospital, Uşak, Turkey.

Introduction: Telogen effluvium (TE) is one of the causes of non-scarring hair loss that occurred commonly 2-3 months after a triggering factor. It was reported that the incidence of TE increased during the COVID-19 (coronavirus disease 2019) pandemic. However, to date, there is no study evaluating the status of COVID-19 before the onset of hair loss in patients with TE. Read More

JAAD Int 2022 Mar 10;6:125-142. Epub 2022 Feb 10.

Division of Dermatology, University of Ottawa, Ottawa, Ontario, Canada.

Over 1 million isotretinoin prescriptions are authorized in the United States per year. An insight into the frequency, dose dependency, timing, and reversibility of hair loss associated with isotretinoin treatment for acne vulgaris could help guide dosing regimens and patient counseling. The objective of this systematic review was to assess the frequency of hair loss in patients with acne vulgaris on <0. Read More

Cureus 2022 Jan 12;14(1):e21160. Epub 2022 Jan 12.

Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, JPN.

Herein, we report a remarkable case of post-coronavirus disease 2019 (COVID-19) diffuse alopecia that gradually improved and recovered, and the hair volume returned approximately to the pre-infection level, seven months after the patient's first diagnosis of COVID-19. Approximately 20% of patients with COVID-19 develop alopecia a few months after the acute infection phase. Telogen effluvium is the major type of COVID-19 sequela secondary to physical or psychological distress. Read More

Int J Dermatol 2022 Feb 7. Epub 2022 Feb 7.

Professor of Medicine, Director of Dermatology, The Ohio State University College of Medicine, Columbus, OH, USA.

Pregnancy prompts many adaptive and unique physiologic modifications, with cutaneous changes being possibly the most noticeable. These cutaneous changes are of interest to physicians, since they must be diagnosed as anticipated normal physiologic changes or potentially harmful and managed accordingly. Research has been conducted on physiologically normal and abnormal cutaneous manifestations of pregnancy but is lacking in regard to the persistence of these changes after delivery. Read More

Dermatol Online J 2021 Oct 15;27(10). Epub 2021 Oct 15.

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Metro Dermatology.

The prevalence of telogen effluvium (TE) has increased during COVID-19. In this study we describe the clinical characteristics of patients with COVID-19-related TE and review the current literature on COVID-19-associated TE. We conducted a retrospective chart review of 66 patients, all of which had COVID-19 infection (confirmed by PCR or antibodies) and had either non-scarring hair loss or TE in Elmhurst, Queens. Read More

Clin Cosmet Investig Dermatol 2022 25;15:117-126. Epub 2022 Jan 25.

Department of Dermatology, Peking University People's Hospital, Beijing, People's Republic of China.

Purpose: The aim of this study is to establish a refined wash test (RWT) and explore the characteristics of daily shedding hair parameters in normal individuals and patients with androgenetic alopecia (AGA) or telogen effluvium (TE).

Materials And Methods: Chinese subjects diagnosed as normal, AGA or TE were enrolled. For the RWT procedure, the subjects were asked to pre-wash their hair 24 hours before the first collection, then to wash and rinse their hair with flowing water above a sink covered with a piece of filtering cloth. Read More