275 results match your criteria Techniques of Local Anesthesia for Prostate Procedures and Biopsies


Transperineal free-hand mpMRI fusion targeted biopsies under local anesthesia for Prostate Cancer Diagnosis: a multicenter prospective study of 1,014 cases.

BJU Int 2020 May 26. Epub 2020 May 26.

Department of Urology, San Giovanni Battista Hospital, Città della Salute e della Scienza and University of Turin, Turin, Italy.

Background: No large multicentre prospective studies ever addressed the outcomes of mpMRI targeted fusion transperineal biopsy (TPFBx) under local anesthesia (LA). The debate upon best biopsy modality is still open.

Patients And Methods: We prospectively screened for inclusion 1,327 men with a positive mpMRI undergoing TPFBx (targeted cores and systematic cores) under LA, at two tertiary referral institutions, from Sep2016 to May2019. Read More

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http://dx.doi.org/10.1111/bju.15121DOI Listing

Does deep sedation with analgesia have positive effects on anxiety, pain and compliance in patients before and after prostate biopsy?

Int J Clin Pract 2020 Apr 28:e13517. Epub 2020 Apr 28.

Department of Urology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Republic of Korea.

Aims: To investigate whether deep sedation for transrectal prostate biopsy could reduce anxiety and pain and enhance rebiopsy compliance.

Methods: A two-centre prospective observation study was conducted under two different anaesthetic conditions: deep sedation with analgesia and local anaesthesia with lidocaine. A 12-core prostate biopsy was taken in all patients. Read More

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http://dx.doi.org/10.1111/ijcp.13517DOI Listing

A Novel Perineal Nerve Block Approach for Transperineal Prostate Biopsy: An Anatomical Analysis-based Randomized Single-blind Controlled Trial.

Urology 2020 Apr 23. Epub 2020 Apr 23.

Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China. Electronic address:

Objective: To develop and validate a novel perineal nerve block approach for transperineal prostate biopsy.

Patients And Methods: Five adult male cadavers were dissected to delineate the superficial and deep branches of the perineal nerve. Afterwards, 90 out of 115 patients were selected and randomly assigned to receive periprostatic, periapical triangle (PAT), or branches of perineal nerve (BPN) block. Read More

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http://dx.doi.org/10.1016/j.urology.2020.01.058DOI Listing

Comparison of the Efficacy of Local Anesthesia Methods and Caudal Regional Anesthesia in Prostate Biopsy Applied Under Transrectal Ultrasonography: A Randomized Controlled Study.

Urol J 2020 Mar 14. Epub 2020 Mar 14.

Ankara Numune Training and Research Hospital, Department of Urology, Ankara, Turkey.

Purpose: To evaluate the efficacy of caudal regional anesthesia and local anesthesia methods in prostate biopsy applied under transrectal ultrasonography.Matherials and Methods: This prospective study included a total of 160 patients randomly separated into 4 equal groups as intrarectal local anesthesia (IRLA), periprostatic local anesthesia (PPLA), combined local anesthesia (IRLA+PPLA), and caudal regional anesthesia (CRA). The patients were evaluated using the pain scores on a visual analog scale. Read More

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http://dx.doi.org/10.22037/uj.v0i0.5503DOI Listing

Guidelines for Transrectal Ultrasonography-Guided Prostate Biopsy: Korean Society of Urogenital Radiology Consensus Statement for Patient Preparation, Standard Technique, and Biopsy-Related Pain Management.

Korean J Radiol 2020 Apr;21(4):422-430

Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.

The Korean Society of Urogenital Radiology (KSUR) aimed to present a consensus statement for patient preparation, standard technique, and pain management in relation to transrectal ultrasound-guided prostate biopsy (TRUS-Bx) to reduce the variability in TRUS-Bx methodologies and suggest a nationwide guideline. The KSUR guideline development subcommittee constructed questionnaires assessing prebiopsy anticoagulation, the cleansing enema, antimicrobial prophylaxis, local anesthesia methods such as periprostatic neurovascular bundle block (PNB) or intrarectal lidocaine gel application (IRLA), opioid usage, and the number of biopsy cores and length and diameter of the biopsy needle. The survey was conducted using an Internet-based platform, and responses were solicited from the 90 members registered on the KSUR mailing list as of 2018. Read More

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http://dx.doi.org/10.3348/kjr.2019.0576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082664PMC
April 2020
1.807 Impact Factor

Transperineal Free-hand mpMRI Fusion-targeted Biopsies Under Local Anesthesia: Technique and Feasibility From a Single-center Prospective Study.

Urology 2020 Jun 13;140:122-131. Epub 2020 Feb 13.

Department of Urology, San Giovanni Battista Hospital, Città della Salute e della Scienza and University of Turin, Turin, Italy.

Objective: To evaluate the feasibility of "in-office" TPFBx under local anesthesia (LA).

Materials And Methods: We prospectively screened for eligibility data of 724 consecutive men undergoing either TPFBx (target and systematic cores) or TPSBx (systematic cores only) from September 2016 to June 2018 due to suspicion of prostate cancer (CaP), according to predefined exclusion criteria.

Results: We included 459 men (TPFBx n = 279 including n = 338 mpMRI lesions, Pi-RADS 4 in 63. Read More

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http://dx.doi.org/10.1016/j.urology.2019.11.078DOI Listing

Feasibility of freehand MRI/US cognitive fusion transperineal biopsy of the prostate in local anaesthesia as in-office procedure-experience with 400 patients.

Prostate Cancer Prostatic Dis 2020 Jan 2. Epub 2020 Jan 2.

Department of Urology, Cantonal Hospital Aarau, Aarau, Switzerland.

Background: Transrectal (TR) ultrasound-guided prostate biopsy is one of the most commonly performed urologic procedures worldwide. The major drawback of this approach is the associated risk for infectious complications. Sepsis rates are increasing due to rising antibiotic resistance, representing a global issue. Read More

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http://dx.doi.org/10.1038/s41391-019-0201-yDOI Listing
January 2020

Efficacy and safety of a combined anesthetic technique for transrectal prostate biopsy: a single center, prospective, randomized study.

Cent European J Urol 2019 16;72(3):258-262. Epub 2019 Sep 16.

Department of Urology, Hospital de Braga, Portugal.

Introduction: A transrectal ultrasound-guided (TRUS) biopsy is the gold standard for diagnosis of prostatic neoplasia. This exam is associated with pain and discomfort, and numerous methods of analgesia during this procedure have been described. There is still no consensus among urologists about the pain control technique that should be performed, even though the periprostatic basal nerve block is the most studied technique. Read More

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http://dx.doi.org/10.5173/ceju.2019.1936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830480PMC
September 2019
4 Reads

Transperineal prostate biopsy with cognitive magnetic resonance imaging/biplanar ultrasound fusion: description of technique and early results.

World J Urol 2019 Nov 2. Epub 2019 Nov 2.

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Park 213, Baltimore, MD, 21287, USA.

Objective: To describe our technique and early results performing transperineal prostate biopsy using cognitive magnetic resonance imaging (MRI)/biplanar ultrasound fusion. Key components of this technique include use of the PrecisionPoint Transperineal Access System (Perineologic, Cumberland, MD) and simultaneous transrectal ultrasound guidance in the axial and sagittal planes.

Patients And Methods: In total, 95 patients (38 studied retrospectively and 57 studied prospectively) underwent a transperineal MRI-targeted prostate biopsy using the technique detailed in this manuscript. Read More

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http://dx.doi.org/10.1007/s00345-019-02992-4DOI Listing
November 2019

Comparisons of cancer detection rate and complications between transrectal and transperineal prostate biopsy approaches - a single center preliminary study.

BMC Urol 2019 Oct 28;19(1):101. Epub 2019 Oct 28.

Department of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No.123, Dapi Rd., Niaosong Dist., Kaohsiung, Taiwan, Republic of China.

Background: Prostate biopsy remains the gold standard approach to verify prostate cancer diagnosis. Transrectal (TR) biopsy is a regular modality, while transperineal (TP) biopsy is an alternative for the patients who display persistently high levels of prostate-specific antigen (PSA) and thus have to undergo repeat biopsy. This study aimed to compare the cancer detection rates between TR and TP approaches and assess the post-bioptic complications of the two procedures. Read More

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http://dx.doi.org/10.1186/s12894-019-0539-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816188PMC
October 2019

Easy Method for Percutaneous Nephrostomy Placement with Transrectal Ultrasonography Probe.

J Laparoendosc Adv Surg Tech A 2019 Dec 29;29(12):1565-1570. Epub 2019 Oct 29.

Department of Urology, Faculty of Medicine, Ordu University, Ordu, Turkey.

Percutaneous nephrostomy (PN), the indispensable interventional procedure in situations such as obstructive uropathy and pyonephrosis, requires serious experience. As a result, many urologists and radiologists avoid this procedure. However, this can leave both doctor and patient in a difficult situation when it is necessary. Read More

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http://dx.doi.org/10.1089/lap.2018.0810DOI Listing
December 2019
1 Read
1.187 Impact Factor

A novel method for pain control: infiltration free local anesthesia technique (INFLATE) for transrectal prostatic biopsy using transcutaneous electrical nerve stimulation (TENS).

Int Urol Nephrol 2019 Dec 6;51(12):2119-2126. Epub 2019 Sep 6.

Department of Urology, Faculty of Medicine, Ondokuzmayis University, Samsun, Turkey.

Purpose: To describe a novel method for the control of pain during prostate biopsies, infiltration free local anesthesia technique (INFLATE) for transrectal prostatic biopsies with no further needle insertions for local anesthetic infiltration.

Methods: A total of 138 men with elevated prostate-specific antigen levels and/or abnormal digital rectal examination findings were included in the study. Of the patients, 73 were assigned to the INFLATE group and 65 to the TRUS-PNB group. Read More

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http://dx.doi.org/10.1007/s11255-019-02277-0DOI Listing
December 2019
2 Reads

In-office Transperineal Prostate Biopsy Using Biplanar Ultrasound Guidance: A Step-by-Step Guide.

Urology 2019 Nov 30;133:247. Epub 2019 Jul 30.

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

Objective: To provide a step-by-step guide for performing in-office transperineal prostate biopsy using biplanar ultrasound guidance.

Patients And Methods: Biopsies are performed using a freehand technique with the PrecisionPoint Transperineal Access System (Perineologic, Cumberland, MD). This disposable needle guide includes 3 components: a rail/clamp subassembly, a needle carriage with 5 aperture holes, and a 15 gauge access needle. Read More

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http://dx.doi.org/10.1016/j.urology.2019.07.021DOI Listing
November 2019
12 Reads

Pelvic plexus block to provide better anesthesia in transperineal template-guided prostate biopsy: a randomised controlled trial.

BMC Urol 2019 Jul 9;19(1):63. Epub 2019 Jul 9.

Department of Urology, Clinical Medical College, Yangzhou University, No. 98 West Nantong Road, Yangzhou, Jiangsu Province, 225001, China.

Background: To evaluate the efficacy of pelvic plexus block (PPB) in relief pain during transperineal template-guided prostate biopsy (TTPB), compared with conventional periprostatic nerve block (PNB).

Methods: From July 2016 to August 2017, 245 patients who were performed TTPB in Clinical Medical College of Yangzhou University were recruited. The patients were randomized into three groups using a random number table. Read More

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http://dx.doi.org/10.1186/s12894-019-0496-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617827PMC
July 2019
6 Reads

Periprostatic nerve block alone versus combined with perineal pudendal nerve block or intrarectal local anesthesia during transrectal ultrasound-guided prostate biopsy: A prospective randomized controlled trial.

Int J Urol 2019 08 17;26(8):833-838. Epub 2019 Jun 17.

Department of Urology, Yuzuncu Yil University Medical Faculty, Van, Turkey.

Objectives: To compare the efficacy, safety and cost of combinations of perineal pudendal nerve block + periprostatic nerve block and intrarectal local anesthesia + periprostatic nerve block with the standard technique (periprostatic nerve block).

Methods: The study was designed as a randomized prospective controlled trial. Patients with elevated serum prostate-specific antigen values (prostate-specific antigen ≥4 ng/mL) and/or abnormal digital rectal examination findings were included in the study. Read More

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http://dx.doi.org/10.1111/iju.14036DOI Listing
August 2019
12 Reads

Efficacy and safety of periprostatic nerve block combined with perineal subcutaneous anaesthesia and intrarectal lidocaine gel in transrectal ultrasound guided transperineal prostate biopsy: A Prospective Randomised Controlled Trial.

Prostate Cancer Prostatic Dis 2020 03 3;23(1):74-80. Epub 2019 Jun 3.

Department of Urology, Xiangya Hospital, Central South University, Changsha City, Hunan Province, P.R. China.

Background: To determine the efficacy and safety of a periprostatic nerve block combined with perineum subcutaneous anaesthesia and intrarectal lidocaine gel for transrectal ultrasound-guided transperineal prostate biopsy (TPBx) through a prospective randomised controlled trial.

Methods: In total, 216 patients from May 2018 to November 2018 were randomly assigned to the experimental group and the control group at a ratio of 1:1. The experimental group received a periprostatic nerve block combined with subcutaneous perineal anaesthesia and intrarectal lidocaine gel. Read More

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http://dx.doi.org/10.1038/s41391-019-0155-0DOI Listing
March 2020
15 Reads
3.425 Impact Factor

Minimally invasive treatment for lower urinary tract symptoms due to benign prostatic hyperplasia. Our initial experience with Urolift® under local anaesthesia and sedation.

Actas Urol Esp 2019 11 31;43(9):488-494. Epub 2019 May 31.

Servicio de Urología, Hospital General Universitario de Valencia, Valencia, España.

Introduction: The treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia with the Urolift® system has been carried out since 2005 with good results in the medium term. In this work, we present our experience performing this technique under local anaesthesia and sedation in 2 Spanish centres.

Material And Methods: A prospective study was conducted with 20 patients treated with Urolift® under local anaesthesia and sedation between April 2017 and April 2018. Read More

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http://dx.doi.org/10.1016/j.acuro.2019.01.007DOI Listing
November 2019
4 Reads

[Effect of multimodal analgesia using periprostatic nerve block anesthesia combined with flurbiprofen in transperineal template-guided prostate biopsy].

Zhonghua Wai Ke Za Zhi 2019 Jun;57(6):428-433

Department of Urology, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China.

To evaluate the effect of multimodal analgesia using periprostatic nerve block anesthesia (PNB) combined with flurbiprofen in patients undergoing transperineal template-guided prostate biopsy (TTPB). Totally 166 patients (aged (68.2±9. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2019.06.007DOI Listing
June 2019
17 Reads

Is Pelvic Plexus Block Superior to Periprostatic Nerve Block for Pain Control during Transrectal Ultrasonography-Guided Prostate Biopsy? A Double-Blind, Randomized Controlled Trial.

J Clin Med 2019 Apr 24;8(4). Epub 2019 Apr 24.

Department of Urology, Gangnam Severance Hospital, Urological Science Institute, Yonsei University College of Medicine, Seoul 06273, Korea.

We evaluated whether pelvic plexus block (PPB) is superior to periprostatic nerve block (PNB) for pain control during transrectal ultrasonography (TRUS)-guided prostate biopsy (PBx). A prospective, double-blind, randomized, controlled study was performed at a single center; 46 patients were enrolled and randomly allocated into two groups: PPB (n = 23) and PNB (n = 23). The visual analogue scale (VAS) was used; pain scores were measured four times: during local anesthesia, probe insertion, sampling procedures, and at 15 min post procedures. Read More

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http://dx.doi.org/10.3390/jcm8040557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517998PMC
April 2019
6 Reads

What is the most effective local anesthesia for transrectal ultrasonography-guided biopsy of the prostate? A systematic review and network meta-analysis of 47 randomized clinical trials.

Sci Rep 2019 03 20;9(1):4901. Epub 2019 Mar 20.

Department of Urology, Gangnam Severance Hospital, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.

We aimed to compare the effectiveness of various local anesthetic methods for controlling prostate biopsy (PBx) related pain using network meta-analysis. Literature searches were performed on PubMed/Medline, Embase, and Cochrane Library up to March 2018. Forty-seven randomized controlled trials, in which the effectiveness of PBx-related pain was investigated using a visual analogue scale after various local anesthetic methods, were included. Read More

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http://www.nature.com/articles/s41598-019-41412-w
Publisher Site
http://dx.doi.org/10.1038/s41598-019-41412-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426994PMC
March 2019
9 Reads

A randomized controlled comparison between periprostatic nerve block and pelvic plexus block at the base and apex of 14-core prostate biopsies.

World J Urol 2019 Dec 12;37(12):2663-2669. Epub 2019 Mar 12.

Department of Urology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Bangdong-gil 38, Sacheon-myeon, Gangneung, Gangwon-do, Republic of Korea.

Purpose: To compare the pain control efficacies of the pelvic plexus block (PPB), periprostatic nerve block (PNB), and controls during a 14-core basal and apical core prostate biopsy.

Methods: This randomized controlled study, performed between January 2015 and January 2016, included patients with an abnormal serum prostate-specific antigen (PSA > 3 ng/mL) level or a palpable nodule on digital rectal examination. The enrolled patients were randomized into three groups: Group 1, intrarectal local anesthesia (IRLA, 10 mL of 2% lidocaine jelly) and PPB with 3. Read More

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http://dx.doi.org/10.1007/s00345-019-02722-wDOI Listing
December 2019
24 Reads

Transperineal Prostate Biopsies Using Local Anesthesia: Experience with 1,287 Patients. Prostate Cancer Detection Rate, Complications and Patient Tolerability.

J Urol 2019 06;201(6):1121-1126

Division of Urology, North York General Hospital , Toronto , Ontario , Canada.

Purpose: We report our experience with transperineal prostate biopsy as well as the cancer diagnosis rate, complications and patient tolerability in 1,287 consecutive patients at risk for prostate cancer.

Materials And Methods: Beginning in October 2016 transperineal prostate biopsy was performed using local anesthesia in all patients undergoing prostate biopsy. Data on prebiopsy characteristics and results, including the cancer detection rate, complications and patient tolerability scores, were collected retrospectively from patient records. Read More

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http://dx.doi.org/10.1097/JU.0000000000000156DOI Listing
June 2019
42 Reads

Multiparametric MRI fusion-guided prostate biopsy in biopsy naive patients: Preliminary results from 80 patients.

Turk J Urol 2019 05 20;45(3):196-201. Epub 2019 Feb 20.

Department of Urology, Erciyes University School of Medicine, Kayseri, Turkey.

Objective: The aim of this prospective study was to evaluate the early results of transrectal prostate biopsies performed under the guidance of multiparametric prostate magnetic resonance imaging (mpMRI) in biopsy naive patients.

Material And Methods: Biopsy naive patients who had prostate-specific antigen level 4-10 ng/mL and/or abnormal digital rectal examination findings and provided informed consent were examined using mpMRI. The study included 80 patients with an MRI-defined lesion with a Prostate Imaging and Reporting and Data System (PIRADS) score of ≥3. Read More

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http://dx.doi.org/10.5152/tud.2019.03710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469728PMC
May 2019
3 Reads

[Intrarectal local anesthesia versus periprostatic nerve block in transrectal prostate biopsy for patients with different prostate volumes: A prospective randomized controlled trial].

Zhonghua Nan Ke Xue 2018 May;24(5):393-398

Department of Urology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.

Objective: To evaluate the analgesic effect of intrarectal local anesthesia (IRLA) versus that of periprostatic nerve block anesthesia (PPNB) in initial transrectal ultrasound-guided prostate biopsy (TRUS-PB) for patients with different prostate volumes (PV).

Methods: A total of 253 patients undergoing initial TRUS-PB in our hospital from January 2014 to November 2017 were divided into three PV groups (<50 ml, 50-100 ml, and >100 ml), each again randomized into three subgroups (control, IRLA, and PPNB) with the random number table method. The pain during the procedure was assessed based on the Visual Analogue Scale (VAS) scores and the blind method was used by the biopsy operator, VAS valuator and data analyst. Read More

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May 2018
17 Reads

Prostate cancer treatment by the latest focal HIFU device with MRI/TRUS-fusion control biopsies: A prospective evaluation.

Urol Oncol 2018 09 6;36(9):401.e1-401.e9. Epub 2018 Aug 6.

Department of Urology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

Objectives: Magnetic resonance imaging/transrectal ultrasound (MRI/TRUS) fusion-guided focal high intensity focused ultrasound (HIFU) therapy of the prostate has recently been developed as a selective HIFU-therapy technique to enable targeted ablation of prostate cancer. Here we report a series of patients treated with focal HIFU therapy, discuss its potential pitfalls, and address controversies concerning the indications.

Materials And Methods: This single-center prospective study reports outcomes of patients treated from September 2014 to March 2016. Read More

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http://dx.doi.org/10.1016/j.urolonc.2018.05.022DOI Listing
September 2018
26 Reads

Cost and efficacy comparison of five prostate biopsy modalities: a platform for integrating cost into novel-platform comparative research.

Prostate Cancer Prostatic Dis 2018 11 9;21(4):524-532. Epub 2018 Jul 9.

Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: The cornerstone of prostate cancer diagnosis remains the transrectal ultrasound-guided biopsy (TRUS-BX), which most frequently occurs in the office setting under local anesthesia. However, there are now other techniques of prostate biopsy aimed at improving outcomes such as patient comfort, significant cancer detection, and infectious complications. The purpose of the present study is to compare the cost and efficacy outcomes of five different approaches. Read More

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http://dx.doi.org/10.1038/s41391-018-0056-7DOI Listing
November 2018
73 Reads

Comparing use of lidocaine periprostatic nerve block and diclofenac suppository alone for patients undergoing transrectal ultrasound guided prostate biopsy.

Cent European J Urol 2018 8;71(1):38-42. Epub 2017 Jan 8.

Department of Urology, Hisar Intercontinental Hospital, Istanbul, Turkey.

Introduction: The objective of this study is to make a comparison between the effectiveness of the diclo- fenac suppository alone and periprostatic local anaesthesia infiltration alone to reduce the pain during a transrectal ultrasound-guided prostate biopsy procedure.

Material And Methods: Between January 2014 and December 2015, 100 patients from two centres who were scheduled for transrectal ultrasound guided prostate biopsy (TRUS Bx) were included in the study. Patients were divided into two groups; diclofenac suppository group (Group 1) and Lidocaine group (Group 2). Read More

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http://dx.doi.org/10.5173/ceju.2017.1381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926629PMC
January 2017
14 Reads

An update on prostate biopsy in the era of magnetic resonance imaging.

Minerva Urol Nefrol 2018 Jun 28;70(3):264-274. Epub 2018 Mar 28.

Unit of Urology, Città di Castello Hospital, ASL Umbria 1, Città di Castello, Perugia, Italy.

Introduction: Prostate cancer (PCa) is a singular disease owing to absence of imaging technique able to detect suspicious glandular area at higher risk of disease. Nowadays, magnetic resonance imaging (MRI) has been used as a way to detect PCa and simplify targeting prostate biopsy (PB). The aim of this study is to review the most recent data regarding standard BP and MRI-guided PB. Read More

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http://dx.doi.org/10.23736/S0393-2249.18.03048-5DOI Listing
June 2018
7 Reads

A comparison of pain control and complications using three different ways of anesthesia in patients undergoing transrectal ultrasound-guided prostate biopsy.

J Res Med Sci 2018 20;23:17. Epub 2018 Feb 20.

Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: We aim to compare the degree of pain control and complications in three types of anesthesia using periprostatic nerve block (PPNB) plus intrarectal local anesthesia (IRLA), low-dose spinal anesthesia, and intravenous (IV) sedation in patients undergoing transrectal ultrasound (TRUS)-guided prostate biopsy.

Materials And Methods: In this clinical trial study, 106 patients were participated from December 2015 to December 2016 at Alzahra Hospital, Isfahan, Iran. Patients were randomly allocated into three groups to receive PPNB plus IRLA ( = 36), low-dose spinal anesthesia ( = 35) and IV sedation ( = 35) before TRUS-guided prostate biopsy. Read More

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http://www.jmsjournal.net/text.asp?2018/23/1/17/225901
Publisher Site
http://dx.doi.org/10.4103/jrms.JRMS_639_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842442PMC
February 2018
8 Reads

Which is better for pain reduction during transrectal ultrasound-guided biopsy of the prostate: Intravenous diazepam, local periprostatic nerve block, or combination? controlled randomized study.

Saudi J Anaesth 2018 Jan-Mar;12(1):16-21

Department of Urology, Faculty of Medicine, Assiut University Hospital, Assiut University, Assiut, Egypt.

Background: Transrectal ultrasound-guided prostate biopsy (TRUSPB) is considered the procedure of choice for the diagnosis of prostate cancer. Men undergoing this biopsy experience high psychological stress. Different studies recommend techniques as sedation, lidocaine gel intrarectally, periprostatic nerve block alone, or nitrous oxide inhalation as effective methods of analgesia during procedural-related pain or discomfort. Read More

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http://dx.doi.org/10.4103/sja.SJA_141_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789491PMC
February 2018
6 Reads

What should be done to minimize pain without any sexual function deterioration in transrectal prostate biopsy?

Cent European J Urol 2017 9;70(4):372-377. Epub 2017 Oct 9.

Medical Park Ankara Hospital, Department of Urology, Ankara, Turkey.

Introduction: The aim of this study was to find an ideal method for the application of a transrectal ultrasound-guided prostate biopsy (TRUS-Bx) without deteriorating patient comfort.

Material And Methods: TRUS-Bx was applied in a total of 93 patients. Taking the application method into consideration, these patients were divided into three groups, each consisting of 31 patients. Read More

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http://dx.doi.org/10.5173/ceju.2017.1442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791401PMC
October 2017
12 Reads

Initial Experience Performing In-office Ultrasound-guided Transperineal Prostate Biopsy Under Local Anesthesia Using the PrecisionPoint Transperineal Access System.

Urology 2018 May 1;115:8-13. Epub 2018 Feb 1.

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

Objective: To describe our procedural technique and initial outcomes performing in-office transperineal prostate biopsies using the PrecisionPoint Transperineal Access System (Perineologic, Cumberland, MD).

Patients And Methods: Following institutional review board approval, we retrospectively reviewed the records of men who underwent an in-office transperineal prostate biopsy using the PrecisionPoint device. Records were reviewed for baseline characteristics, biopsy results, and postbiopsy complications. Read More

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http://dx.doi.org/10.1016/j.urology.2018.01.021DOI Listing
May 2018
19 Reads

MR-guided biopsy and focal therapy: new options for prostate cancer management.

Curr Opin Urol 2018 03;28(2):93-101

UCLA Department of Urology, David Geffen School of Medicine, Los Angeles, California, USA.

Purpose Of Review: Options for prostate cancer management are rapidly expanding. The recent advent of MRI technology has led to guided prostate biopsies by radiologists working in-bore or by urologists using MR/US fusion technology. The resulting tumor visualization now provides the option of focal therapy. Read More

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http://dx.doi.org/10.1097/MOU.0000000000000471DOI Listing
March 2018
21 Reads

Effect of Music on Outpatient Urological Procedures: A Systematic Review and Meta-Analysis from the European Association of Urology Section of Uro-Technology.

J Urol 2018 05 7;199(5):1319-1327. Epub 2017 Dec 7.

University of Southampton, University Hospital Southampton National Health Service Trust, Southampton, United Kingdom. Electronic address:

Purpose: Music is a practical, inexpensive and harmless analgesic and anxiolytic. An increasing number of original studies have been performed to investigate its potential application in urology. Our aim was to identify the effect of music on outpatient based urological procedures. Read More

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http://dx.doi.org/10.1016/j.juro.2017.11.117DOI Listing
May 2018
110 Reads

A Comparison of Prilocaine vs Prilocaine + Bupivacaine in Periprostatic Block in Ambulatory Prostate Biopsies: A Single-Blind Randomized Controlled Study.

Pain Med 2018 10;19(10):2069-2076

Anesthesia and Reanimation, Saglik Bilimleri University, Samsun Training and Research Hospital, Samsun, Turkey.

Objective: The purpose of this study was to evaluate the analgesic effect of a prilocaine + bupivacaine combination in patients undergoing periprostatic nerve block (PNB) by comparing its effects with those of prilocaine alone.

Design: Single center, single-blind, prospective descriptive study.

Subjects: Four hundred patients with transrectal prostate biopsy pain. Read More

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http://dx.doi.org/10.1093/pm/pnx249DOI Listing
October 2018
10 Reads

Retrospective evaluation of the effects of periprostatic local anesthesia on recurrent prostate biopsy.

Agri 2017 Oct;29(4):151-156

Department of Urology, Samsun Training and Research Hospital, Health Sciences University, Samsun, Turkey.

Objectives: The aim of the study was investigate the pain palliation effect of 2% dose of lidocaine on the periprostatic nerve block in prostate biopsy patients.

Methods: Extended (12 cores) and saturation (22 cores) biopsy patients were included. The patients were separated into three groups: extended biopsy patients (Group I), saturation biopsy patients (Group II), and control group patients undergoing a biopsy procedure for the first time (Group III). Read More

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http://dx.doi.org/10.5505/agri.2017.94834DOI Listing
October 2017
14 Reads

Prospective comparison among three intrarectal anesthetic treatments combined with periprostatic nerve block during transrectal ultrasonography-guided prostate biopsy.

World J Urol 2018 Feb 23;36(2):193-199. Epub 2017 Nov 23.

Research Center Applied to Public Health, School of Medicine, Autonomous University of Sinaloa, Campus 2. Av. Cedros y Calle Sauces. Fracc. Los Fresnos, 80019, Culiacan, Sinaloa, Mexico.

Background: Recent trends in prostate biopsy analgesia suggest a combination anesthetic to provide better pain relief than periprostatic nerve block (PPNB) alone. This study aimed to demonstrate the efficacy and safety of three intrarectal local anesthesia (IRLA) combined with PPNB in patients undergoing transrectal ultrasonography (TRUS)-guided prostate biopsy.

Methods: In this prospective, randomized study, 120 prostate biopsy patients were equally divided into four IRLA groups: group 1 (placebo) received simple lubrication; group 2 received 2% lidocaine gel; group 3 received 100 mg indomethacin suppository and group 4 received 5% prilocaine/lidocaine (EMLA) cream. Read More

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http://dx.doi.org/10.1007/s00345-017-2136-zDOI Listing
February 2018
26 Reads

The Efficiency and Safety of Intrarectal Topical Anesthesia for Transrectal Ultrasound-Guided Prostate Biopsy: A Systematic Review and Meta-Analysis.

Urol Int 2017 30;99(4):373-383. Epub 2017 Oct 30.

Objective: The study aims to review the current evidence to determine the efficiency and safety of intrarectal topical anesthesia (ITA) for transrectal ultrasound-guided prostate biopsy.

Materials And Methods: A comprehensive search of the literature was performed using Medline, Embase and Cochrane central register of controlled trials. All randomized controlled trials (RCTs) comparing the efficacy and safety of periprostatic nerve block (PNB), ITA, and PNB combined with ITA were included. Read More

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http://dx.doi.org/10.1159/000481830DOI Listing
July 2018
16 Reads

[Application of flurbiprofen axetil in pain management associated during transrectal ultrasound-guided prostate biopsy].

Beijing Da Xue Xue Bao Yi Xue Ban 2017 08;49(4):643-647

Department of Urology,Peking University People's Hospital,Beijing 100044, China.

Objective: To examine the effects of perioperative intravenous administration of flurbiprofen axetil (FA) on pain associated with transrectal ultrasound-guided prostate biopsy.

Methods: This was a randomized,controlled study. Eighty-one patients who underwent 12 core prostate biopsy were included in the study. Read More

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August 2017
24 Reads

Safety of transrectal ultrasound-guided prostate biopsy in patients affected by Crohn's disease.

Arch Ital Urol Androl 2017 Jun 30;89(2):106-109. Epub 2017 Jun 30.

Department of Urology, University Hospital "Ospedali Riuniti", Ancona.

Purpose: Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. It is usually considered a contraindication to transrectal ultrasound-guided prostate biopsy (TRUSBx). The aim of this study was to investigate the safety of TRUSBx in a small cohort of patients with CD. Read More

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http://dx.doi.org/10.4081/aiua.2017.2.106DOI Listing
June 2017
80 Reads

Timing interval from peri-prostatic block to biopsy impacts procedural pain.

Can J Urol 2017 Jun;24(3):8795-8801

Department of Urology, Mayo Clinic, Jacksonville, Florida, USA.

Introduction: To compare visual analog scale (VAS) pain scores between patients with a 2-minute versus 10-minute delay of peri-prostatic lidocaine injection prior to transrectal ultrasound-guided prostate biopsies (TRUS-bx).

Materials And Methods: Eighty patients who underwent standard 12-core TRUS-bx by a single surgeon were prospectively randomized into four different treatment arms: bibasilar injection with a 2-minute delay, bibasilar injection plus a single apical injection with a 2-minute delay, bibasilar injection with a 10-minute delay, and bibasilar injection plus a single apical injection with a 10-minute delay. Patients were asked to report their level of pain on the VAS (0-10, with 10 indicating unbearable pain) at the following intervals: probe insertion (baseline), after each core, and post-procedure. Read More

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June 2017
23 Reads

Magnetic resonance imaging targeted transperineal prostate biopsy: a local anaesthetic approach.

Prostate Cancer Prostatic Dis 2017 09 9;20(3):311-317. Epub 2017 May 9.

Division of Surgery and Interventional Science, University College London, London, UK.

Background: Despite high rates of disease misclassification and sepsis, the use of transrectal biopsy remains commonplace. Transperineal mapping biopsies mitigate these problems but carry increased cost and patient burden. Local anaesthetic, multiparametric magnetic resonance imaging (MRI)-targeted transperineal biopsy may offer an alternative. Read More

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http://dx.doi.org/10.1038/pcan.2017.13DOI Listing
September 2017
46 Reads

Prospective comparison of the efficacy of caudal versus periprostatic nerve block, both with intrarectal local anesthesia, during transrectal ultrasonography-guided prostatic needle biopsy.

Scand J Urol 2017 Aug 26;51(4):245-250. Epub 2017 Apr 26.

a Department of Urology , Jikei University School of Medicine , Tokyo , Japan.

Objective: The aim of this study was to compare the effectiveness of caudal block (CB) versus periprostatic nerve block (PPNB), both with intrarectal local anesthesia (IRLA), in reducing pain during transrectal ultrasonography (TRUS)-guided prostatic biopsy.

Materials And Methods: This study included 532 patients: 266 patients received CB with IRLA and 266 patients PPNB with IRLA. A visual analogue scale (VAS) was applied to prospectively evaluate pain (1) at induction of anesthesia, (2) at insertion of the TRUS probe, (3) at needle penetration to the prostate, and (4) throughout the biopsy procedure. Read More

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http://dx.doi.org/10.1080/21681805.2017.1318299DOI Listing
August 2017
42 Reads

Focal Laser Ablation of Prostate Cancer: Feasibility of Magnetic Resonance Imaging-Ultrasound Fusion for Guidance.

J Urol 2017 10 8;198(4):839-847. Epub 2017 Apr 8.

Department of Urology, University of California-Los Angeles, Los Angeles, California; Center for Advanced Surgical and Interventional Technology, University of California-Los Angeles, Los Angeles, California. Electronic address:

Purpose: Focal laser ablation is a potential treatment in some men with prostate cancer. Currently focal laser ablation is performed by radiologists in a magnetic resonance imaging unit (in bore). We evaluated the safety and feasibility of performing focal laser ablation in a urology clinic (out of bore) using magnetic resonance imaging-ultrasound fusion for guidance. Read More

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http://dx.doi.org/10.1016/j.juro.2017.04.017DOI Listing
October 2017
67 Reads

Transperineal prostate biopsy - tips for analgesia.

BJU Int 2017 08 25;120(2):164-167. Epub 2017 May 25.

Department of Surgery, Austin Health, University of Melbourne, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/bju.13859DOI Listing
August 2017
45 Reads

Transperineal gold marker implantation for image-guided external beam radiotherapy of prostate cancer : A single institution, prospective study.

Strahlenther Onkol 2017 Jun 2;193(6):452-458. Epub 2017 Feb 2.

Centre of Radiotherapy, National Institute of Oncology, Ráth György u. 7-9, 1122, Budapest, Hungary.

Purpose: To present the feasibility and complications of transperineal fiducial marker implantation in prostate cancer patients undergoing image-guided radiotherapy (IGRT) METHODS AND MATERIALS: Between November 2011 and April 2016, three radiopaque, gold-plated markers were transperineally implanted into the prostate of 300 patients under transrectal ultrasound guidance and with local anaesthesia. A week after the procedure patients filled in a questionnaire regarding pain, dysuria, urinary frequency, nocturia, rectal bleeding, hematuria, hematospermia or fever symptoms caused by the implantation. Pain was scored on a 1-10 scale, where score 1 meant very weak and score 10 meant unbearable pain. Read More

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http://dx.doi.org/10.1007/s00066-017-1104-2DOI Listing
June 2017
97 Reads

Transrectal ultrasound (TRUS) guided prostate biopsy: Three different types of local anesthesia.

Arch Ital Urol Androl 2016 Dec 30;88(4):308-310. Epub 2016 Dec 30.

Unit of Urology, Department of Human Pathology, University of Messina, Messina,.

Transrectal Ultrasound (TRUS) guided prostate biopsy is regarded as the gold standard for prostate cancer diagnosis. The majority of patients perceive TRUS-guided prostate biopsy as a physically and psychologically traumatic experience. We aimed to compare in this paper the efficacy of three different anesthesia techniques to control the pain during the procedure. Read More

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http://www.pagepressjournals.org/index.php/aiua/article/view
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http://dx.doi.org/10.4081/aiua.2016.4.308DOI Listing
December 2016
64 Reads

Local anesthesia for pain control during transrectal ultrasound-guided prostate biopsy: a systematic review and meta-analysis.

J Pain Res 2016 11;9:787-796. Epub 2016 Oct 11.

Beijing Tian Tan Hospital, Capital Medical University, Neurology Research Division, China National Clinical Research Center for Neurological Disease, Beijing, People's Republic of China.

Background: A meta-analysis was performed to evaluate the efficacy and safety of intrarectal local anesthestic (IRLA), periprostatic nerve block (PPNB), and the combined modalities in alleviating the pain during transrectal ultrasound (TRUS)-guided prostate biopsy.

Materials And Methods: A literature review was performed to identify all published randomized controlled trials (RCTs) about IRLA vs no anesthesia or placebo gel; PPNB vs no injection, periprostatic placebo injection, or IRLA; combined PPNB and IRLA vs PPNB alone; and combined PPNB and intraprostatic nerve block (IPNB) vs PPNB alone before TRUS-guided biopsy. Sources included MEDILINE, EMBASE, and Cochrane Library from 1980 to 2016. Read More

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http://dx.doi.org/10.2147/JPR.S117451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067058PMC
October 2016
40 Reads

May ultrasound probe size influence pain perception of needle piercing during transrectal prostate biopsy? A prospective evaluation.

Arch Ital Urol Androl 2016 Oct 5;88(3):223-227. Epub 2016 Oct 5.

Surgery Department, Section of Urology, ASUR Marche Area Vasta 3, Macerata Hospital, Macerata.

Introduction And Objective: Transrectal ultrasound guided prostate biopsy (TRUS-Bx) is the definitive step in the diagnosis of prostate cancer (CaP). Patients (pts) generally experience significant pain during the procedure at the point that biopsy should be accompanied by some form of anesthesia. Several different factors influence pain perception (PP) during TRUS-Bx. Read More

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http://www.pagepressjournals.org/index.php/aiua/article/view
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http://dx.doi.org/10.4081/aiua.2016.3.223DOI Listing
October 2016
29 Reads

Central zone lesions on magnetic resonance imaging: Should we be concerned?

Urol Oncol 2017 01 28;35(1):31.e7-31.e12. Epub 2016 Sep 28.

Department of Urology, Rush University Medical Center, Chicago, IL.

Introduction And Objective: The Prostate Imaging Reporting and Data System (PI-RADS) score was developed to evaluate lesions in the peripheral and transition zone on multiparametric magnetic resonance imaging (mpMRI) of the prostate. We aim to determine if the PI-RADS scoring system can be used to evaluate central zone lesions on mpMRI.

Materials And Methods: A retrospective review of 73 patients who underwent mpMRI/ultrasound (US) fusion-guided biopsy of 143 suspicious lesions between February 2014 and October 2015 was performed. Read More

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http://dx.doi.org/10.1016/j.urolonc.2016.08.006DOI Listing
January 2017
31 Reads