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Lasers Surg Med 2020 Apr 13. Epub 2020 Apr 13.

Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, Boston, Massachusetts, 02114.

Background And Objectives: The use of picosecond laser in dermatology was originally focused on optimizing the removal of unwanted tattoos. Subsequent advances in this technology have broadened its clinical indications to include treatment of benign pigmented lesions, photodamage, melasma, and scar revision. In this systematic review, evidence-based recommendations are developed for the use of picosecond laser in dermatology. Read More

Radiography (Lond) 2020 Mar 31. Epub 2020 Mar 31.

GenesisCare Nottingham, The Park centre of oncology, Sherwood Lodge Drive, Nottingham, NG5 8RX, UK.

Introduction: An evaluation to compare the traditional tattoo based set up procedure with a surface guided method to assess the possibility of eliminating permanent tattoos in breast cancer patents who are undergoing radiotherapy to the breast/chest wall.

Methods: Forty-three patients that were having radiotherapy to the breast or chest wall were included in this evaluation. The patients were divided into two groups and further divided into 2 sub-groups. Read More

Dermatology 2020 Apr 2:1-7. Epub 2020 Apr 2.

Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland,

Background: To date, information on laser treatment of accidental tattoos is limited.

Objectives: This study analyzes the efficacy and safety of quality-switched ruby, quality-switched Nd:YAG and picosecond lasers in the treatment of accidental hyperpigmentation in a larger patient cohort. To date, there is limited information on laser therapy of accidental hyperpigmentation. Read More

Lasers Surg Med 2020 Mar 24. Epub 2020 Mar 24.

Candela Corporation, 251 Locke Drive, Marlborough, Massachusetts, 01752.

Background And Objectives: Laser-pumped lasers enable driving a secondary wavelength through pumping with a primary device. Here we investigate the first 730 nm laser-pumped laser for efficacy in tattoo removal.

Study Design/materials And Methods: Fifteen subjects with 20 tattoos were enrolled to investigate the effect of a new 730 nm, titanium-sapphire laser-pumped laser at removing decorative tattoos. Read More

J Cosmet Dermatol 2020 Mar 20. Epub 2020 Mar 20.

Private Practice, Dermatology OPClinic, Tripoli, Libya.

Background: Tattooing is an ancient practice that has been performed all over the world which is used to beautify the skin and augment beauty. Regrettable tattoos are treated with Q switch lasers, in many sessions, and the effectiveness is doubtful.

Objectives: The aim of this paper is to demonstrate how a unique protocol of R20 Q switch Nd YAG laser, can be employed successfully in removing long standing facial tattoos, in skin type IV, in an effective disciplined timing and cost wise modalities. Read More

Lasers Surg Med 2019 Dec 30. Epub 2019 Dec 30.

Laser & Skin Surgery Center of New York, 317 E 34th St, 11th Floor, New York, New York, 10016.

Background And Objectives: Q-switched (QS) and picosecond lasers can effectively and safely remove unwanted tattoo pigments. Cosmetic mucosal tattoos are rare and there are only a handful of cases of successful laser tattoo removal, all with QS 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser.

Study Design/materials And Methods: A 19-year-old Fitzpatrick skin-type II female presented for treatment of a 6-month-old, black tattoo on the mucosal surface of her lower lip. Read More

Lasers Surg Med 2019 Dec 11. Epub 2019 Dec 11.

Dermatology and Laser Surgery Center, Houston, Texas.

Background And Objectives: Nanosecond Q-switched lasers have been used for the removal of traditional and cosmetic tattoos. Picosecond lasers utilize pulse durations of 10 and provide more efficient clearance of tattoos. Safe and effective removal of tattoos is especially important in cosmetically sensitive areas such as the face. Read More

Lasers Surg Med 2019 Dec 1. Epub 2019 Dec 1.

Cosmetic Laser Dermatology, San Diego, California, 92121.

Background And Objectives: We present a case of laser tattoo removal treated with 15 different combinations using picosecond 1064 nm, picosecond 755 nm, nanosecond 755 nm, and a fractionated CO laser, both with and without a perfluorodecalin (PFD) patch to ascertain the most effective approach. STUDY DESIGN/MATERIALS AND METHODS: A single lower extremity black tattoo was divided into 15 treatment sections allowing for testing of various laser and PFD combinations. Sectioned treatment was conducted until a treatment superiority was noted. Read More

Lasers Med Sci 2019 Nov 23. Epub 2019 Nov 23.

Dermalase Research Unit, Glasgow, UK.

Lasers Surg Med 2019 Nov 14. Epub 2019 Nov 14.

Luce Tokyo Aesthetic Clinic, Tokyo, Japan.

Background And Objectives: Tattoo removal by laser has been mostly performed using Q-switched laser, which has nanosecond pulse width. In recent years, the efficacy of treatment with picosecond pulse width laser has also been reported.

Study Design/materials And Methods: Using a picosecond-domain, neodymium-doped yttrium-aluminum-garnet laser with a potassium-titanyl-phosphate frequency-doubling crystal, we performed a retrospective clinical study with combination treatment using pulse widths of 750 ps and 2 ns. Read More

Lasers Surg Med 2020 Jan 19;52(1):70-76. Epub 2019 Sep 19.

Soliton, Inc., Houston, Texas, 77081.

Background And Objectives: The ability to provide improved tattoo fading using multiple laser passes in a single office laser tattoo removal session is limited. In part, this is due to the loss of laser effectiveness caused by epidermal and dermal vacuole "whitening" generated during the initial laser pass at the tattoo site. The Rapid Acoustic Pulse (RAP) device generates acoustic shock wave pulses that clear epidermal and dermal vacuoles to enable multiple laser passes in a single office laser tattoo removal session. Read More

Int J Prison Health 2019 12 9;15(4):308-315. Epub 2019 Jul 9.

Department of Dermatology, UCSD School of Medicine, San Diego, California, USA.

Purpose: The purpose of this paper is to describe a sustainable free laser tattoo removal clinic for economically disadvantaged adult probationers.

Design/methodology/approach: This paper describes the partnerships, methods and challenges/lessons learned from the implementation of a free monthly laser tattoo removal program for adult probationers within a medical school setting in California.

Findings: Possible patients are identified via a collaboration with the county's Probation Department. Read More

Cornea 2019 Nov;38(11):1400-1405

Department of Ophthalmology, Université de Montréal, Montreal, QC, Canada.

Purpose: To report outcomes of keratopigmentation (KP) with commercial black ink in the treatment of dysphotopsia secondary to laser peripheral iridotomies (LPI) using manual anterior stromal puncture (ASP) and manual lamellar pocket (LP).

Methods: This is a retrospective case series of eyes that underwent KP for treatment of dysphotopsia secondary to LPI. Patients' postoperative symptoms were categorized as resolved, improved, no change, or worse. Read More

Dermatol Ther 2019 09 10;32(5):e13069. Epub 2019 Sep 10.

Laser Cutaneous Cosmetic & Plastic Surgery Unit, Villa Donatello Clinic, Florence, Italy.

Traumatic tattoos can be treated with several methods, including mechanical and chemical devices. However, they are rarely used due to the high risk of permanent side effects such as scarring and depigmentation. Recently, laser devices, especially the Q-switched (QS) laser and the pulsed dye laser (PDL), applied in combination, have achieved complete clearance of the lesions without any risk of side effects. Read More

Dermatol Ther 2019 09 23;32(5):e13042. Epub 2019 Aug 23.

Department of Health Sciences, Unit of Dermatology, Magna Graecia University, Catanzaro, Italy.

Laser is a widely accepted tool for tattoo removal, with standardized treatment protocols. Nevertheless, cosmetic tattoo removal may be challenging, because tattoos are performed in proximity of "sensitive" areas and because the ink used in cosmetic tattoos may contain substances that are not standardized and may modify their color at a high temperature. In this case series, we aim to evaluate the effectiveness of Q-switched (QS) Nd:YAG laser for cosmetic tattoo removal. Read More

J Biophotonics 2019 10 20;12(10):e201800484. Epub 2019 Jun 20.

Laser Science and Technology Centre (LASTEC), DRDO, Delhi, India.

Visible lasers emitting in the green spectral region are being routinely employed in various medical and defense fields namely treatment of pigmented lesions, tattoo inks, port wine stains, dazzling the target or mob dispersal. Despite their increasing applications, lasers also tend to pose occupational hazards to operators, ancillary personnel, individuals undergoing laser therapies. This study was aimed at investigating the effects of different doses of 532-nm continuous wave laser on rat skin. Read More

J Am Acad Dermatol 2019 Sep 11;81(3):e59-e60. Epub 2019 May 11.

Laser & Skin Surgery Center of New York, New York, New York; Ronald O. Perelman Department of Dermatology, New York University, New York, New York.

Lasers Surg Med 2019 May 8. Epub 2019 May 8.

Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York, 10022, USA.

Background: Reflectance confocal microscopy (RCM) is a developing approach for noninvasive detection of oral lesions with label-free contrast and cellular-level resolution. For access into the oral cavity, confocal microscopes are being configured with small-diameter telescopic probes and small objective lenses. However, a small probe and objective lens allows for a rather small field-of-view relative to the large areas of tissue that must be examined for diagnosis. Read More

J Cutan Aesthet Surg 2019 Jan-Mar;12(1):49-51

Department of Dermatology, DermaClinix-The Complete Skin and Hair Solution Center, New Delhi, India.

Q-switched Nd:YAG laser remains the gold standard for tattoo removal, but still some tattoos are not completely removed in a specified period as desired by the patient. Herein, we present a case report of 23-year-old patient who came to the outpatient department for tattoo removal. The tattoo measured around 20cm × 18cm and was located on the back. Read More

Skin Res Technol 2019 Sep 6;25(5):683-692. Epub 2019 May 6.

Department of Dermatology and Cutaneous Biology Research Center, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea.

Background: Long-pulsed (LP) lasers at pulse durations of 1-300 ms have been used to destroy nests of nevi cells by selectively targeting pigment chromophores.

Objective: To evaluate dual-wavelength LP laser-induced tissue reactions.

Methods: The patterns of LP 755-nm alexandrite (Alex) and/or 1064-nm neodymium (Nd):yttrium-aluminum-garnet (YAG) laser-induced tissue reactions were macroscopically evaluated using a tattoo-embedded phantom. Read More

J Cosmet Laser Ther 2019 22;21(6):328-331. Epub 2019 Apr 22.

Faculty of Medicine, Dermatology, Minia University , El Minia , Egypt.

: Tattoos have played an important role in various human cultures for thousands of years. The creation of high power, short pulse Q-switched lasers (QS) has provided a tool for considerable therapeutic advances in tattoo removal. : The aim of the study is to correlate the clinical efficacy of QS Nd: YAG laser for tattoo removal with histological as well as histometric findings. Read More

Talanta 2019 Jul 11;199:203-211. Epub 2019 Feb 11.

Laser Research Group, Physics Department, King Fahd University of Petroleum and Minerals, P.O. Box 5047, Dhahran 31261, Saudi Arabia.

Commercially available ready to use henna paste, procured from the local market in Pakistan were tested to find the level of hazardous element, lead present in the samples, using Laser Induced Breakdown Spectroscopy (LIBS). The source of lead in the ready to use henna is from the artificial chemical additives in henna paste, added to enhance the color and also to speed up the dying of the henna tattoo in hand, feet, and body. Henna tattooing is an inevitable practice in the social events in the cultures of the Indian subcontinent and the Arabian Peninsula. Read More

Lasers Surg Med 2019 09 12;51(7):616-624. Epub 2019 Mar 12.

Bioengineering Program and Institute for Bioengineering Research, University of Kansas, Lawrence, Kansas.

Background And Objective: Combined laser and ultrasound treatments have been found to have synergistic effects, which may be of particular note in dermatology. We aim to investigate the potential of this technology for dermatology through in vitro and ex vivo experiments.

Methods: In vitro tissue phantoms made of agar and tattoo ink and tattooed ex vivo chicken breast tissue were used. Read More

Lasers Surg Med 2019 08 1;51(6):491-494. Epub 2019 Feb 1.

SkinCare Physicians, 1244 Boylston Street, Suite 103, Chestnut Hill, Massachusetts, 02467.

Objectives: Measure the sound levels produced by various lasers commonly used during routine outpatient cosmetic surgery to determine whether or not their use exceeds exposure levels set forth by the US National Institute for Occupational Safety and Health (NIOSH) and the US Occupational Safety and Health Administration (OSHA).

Materials And Methods: Using two different meters, the sound levels of lasers commonly used in cosmetic surgery were recorded during various procedures for several indications: tattoo removal, treatment of lentigines and pigmented lesions, facial erythema and vascular lesions, hair removal and resurfacing of acne scars, and photoaging.

Results: All but five lasers had a maximum sound level below 85 dBA, the limit proposed by NIOSH. Read More

Dermatol Surg 2019 02;45(2):183-194

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Philadelphia, Pennsylvania.

Background: Picosecond pulse duration lasers (PS) have altered the field of dermatology. PS were initially used in tattoo removal, to optimize efficacy and reduce side effects with nanosecond domain lasers. More recently, they have been demonstrated to be effective in the treatment of pigmentary disorders, acne scarring, and photoaging. Read More

Photochem Photobiol Sci 2019 Feb;18(2):349-358

Department of Dermatology, University of Regensburg, Germany.

Decorative tattoos including permanent make-up are very popular world-wide. However, some people regret tattooing and seek tattoo removal. Tattooed skin contains numerous solid particles of tattoo pigments. Read More

J Dtsch Dermatol Ges 2018 Dec 12;16(12):1417-1423. Epub 2018 Nov 12.

Department of Dermatology, Venereology and Allergology, Leipzig University Medical Center, and Medical Faculty, Leipzig University, Leipzig, Germany.

Technical advances in recent years have led to new dermatologic laser systems, light sources, and treatment concepts. Commonly used wavelengths - generated today with LED-based devices - allow for the combination of various tissue effects and are associated with improved outcomes. Laser hair removal has become more efficient with the use of diode lasers that emit multiple wavelengths simultaneously. Read More

Lasers Surg Med 2019 01 25;51(1):14-22. Epub 2018 Oct 25.

Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.

Background And Objectives: Cutaneous pigmentary disorders are both more common and more difficult to treat in patients with skin color given the higher melanin content in the epidermis. Although Q-switched lasers are widely considered to be the standard treatment for both epidermal and dermal pigmentary conditions, a very high risk of post-inflammatory hyperpigmentation (PIH) of up to 25% is seen in patients with skin of color. Recently, the novel picosecond laser with pulse durations operating at sub-nanosecond domains has been shown to be effective in tattoo removal and in the treatment of acne scars. Read More

Photomed Laser Surg 2018 Dec 11;36(12):667-675. Epub 2018 Oct 11.

Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo/SP, Brazil.

To determine the optimal parameters of power, energy, and time for the application of a carbon dioxide laser for Tribal Black ink tattoo removal. The use of antiquated techniques to remove tattoos demonstrates the difficulty of making advances in this field. Studies by the American Society for Dermatologic Surgery have shown that 5% of the global population has at least one tattoo on the body, with 10% of them wanting a tattoo to be removed. Read More

Lasers Surg Med 2019 01 12;51(1):23-26. Epub 2018 Oct 12.

Department of Dermatology, University of Texas Health Sciences Center, Houston, Texas.

Background: The topical transparent perfluorodecalin-infused (PFD) silicone patch has been demonstrated to reduce epidermal whitening produced in association with laser-assisted tattoo removal. This optical clearing agent has enabled multiple laser passes to be made in one treatment session. Previous studies using the PFD patch have showed enhanced clearance with picosecond and Q-Switched lasers on blue/black tattoos in Fitzpatrick skin types I-III. Read More

Pediatr Dermatol 2018 Nov 10;35(6):e430-e431. Epub 2018 Oct 10.

Laser & Skin Surgery Center of New York, New York City, New York.

We report a case of successful treatment of a traumatic tattoo in a 2-year-old patient. He presented with a green discoloration on the left infraorbital region after his sister accidentally hit him with a face paint brush while playing together. A single treatment with an alexandrite picosecond laser resulted in a complete clearance without any side effects for this disfiguring condition. Read More

Dermatol Ther 2019 01 8;32(1):e12766. Epub 2018 Nov 8.

Derma Center Aesthetic Laser Clinic, Guadalajara, Jalisco, Mexico.

Eur J Ophthalmol 2019 Sep 4;29(5):NP1-NP4. Epub 2018 Oct 4.

Department of Ophthalmology, 4th Military Hospital, Wroclaw, Poland.

Introduction: We report a case of patient who underwent bilateral eyeball tattoo procedure for cosmetic purpose complicated with intraocular dye injection which led to ocular inflammation, secondary glaucoma, and cataract.

Case Description: A 21-year-old female presented to emergency department with severe right eye pain and photophobia 21 days after conjunctival tattooing procedure. Slit-lamp examination revealed right-sided eyelid edema and black deposits of tattoo ink under the bulbar conjunctiva. Read More

Lasers Med Sci 2019 Jun 3;34(4):703-709. Epub 2018 Oct 3.

Department of Dermatology, Feinberg School of Medicine, Northwestern University, 676 N. St Clair St, Ste 1600, Chicago, IL, 60611, USA.

Non-invasive skin-tightening devices can induce thermal denaturation and skin shrinkage via externally applied radiofrequency emissions or high-frequency ultrasound. Therefore, the purpose of this study is to develop and test a method for measurement of skin reduction associated with application of such energy devices. Twenty-five healthy participants with mild to moderate skin laxity of the arms were enrolled. Read More

PLoS One 2018 6;13(9):e0203370. Epub 2018 Sep 6.

Department of Dermatology, College of Medicine, Dankook University, Cheonan, Chungnam, Republic of Korea.

Picosecond lasers have emerged as the leading technology for tattoo removal due to their shorter pulse lengths. To clarify the features of picosecond lasers, we compared picosecond and nanosecond lasers in their ability to remove multi-colored tattoo in an animal model. We first compared a nanosecond quality-switched Nd:YAG laser with picosecond Alexandrite and quality-switched Nd:YAG lasers and then the picosecond quality-switched Nd:YAG laser with the picosecond Alexandrite laser, using a guinea pig model. Read More

Ugeskr Laeger 2018 Aug;180(34)

13% of the Danish population have tattoos and of these, 16% regret. In this case report, a 26-year-old woman presented to an accident and emergency department with blisters after laser removal of a tattoo on her lower leg. The blisters were only located at the laser-treated area of the tattoo, and they were successfully treated with local steroid class 3 and sun protection. Read More

Lasers Surg Med 2018 09 25;50(9):890-892. Epub 2018 Jun 25.

Department of Dermatology, University of Texas Health Sciences Center, Houston, Texas.

Background: Conventional tattoo removal consists of single-pass treatments, spaced 7-8 weeks apart, for a total of 7-10 sessions. A major limiting factor of this procedure is the development of cavitation bubbles and vacuoles within the epidermis and dermis that result from the rapid heating of tattoo particles by the laser. While multiple-pass methods using the R20 protocol or the PFD patch enhance tattoo removal through epidermal clearance, they have no effect on deep-intradermal pigment associated vacuoles that arise from treatment with lasers such as the Q-switched laser. Read More

Dermatol Surg 2018 12;44(12):1565-1570

Washington Institute of Dermatologic Laser Surgery, Washington, District of Columbia.

Background: Cosmetic tattoos such as eyeliner, brow liner, and lip liner have become increasingly popular in the United States and throughout the world. For a variety of reasons, patients frequently regret their tattoos and request their removal; however, removal is often complicated by the aesthetically sensitive location of these specialized tattoos and the fact that they often contain white metallic compounds that darken on pigment-specific laser irradiation.

Objective: To review the clinical use, effectiveness, and safety of an ablative laser technique for cosmetic tattoos. Read More

Lasers Surg Med 2018 May 20. Epub 2018 May 20.

Syneron-Candela Corporation, 530 Boston Post Road, Wayland, Massachusetts 01778.

Background: Green, blue, and purple tattoo pigments are often the colors most resistant to laser removal. Recently, the first ever production picosecond-domain laser with a 785 nm wavelength was developed to improve the rate of clearance of green, blue, and purple tattoo inks.

Methods: Twenty-two tattoos from 15 subjects with skin phototypes II-IV were enrolled in the study. Read More

Dermatol Surg 2019 03;45(3):473-475

Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri.

J Cosmet Laser Ther 2019 8;21(2):116-117. Epub 2018 May 8.

a Department of Dermatology , Boston University , Boston , MA , USA.

Patients with a history of intravenous drug usage (IVDU) often develop pathognomonic linear hyperpigmented dermatoses near injection sites. This drug use-related pigmentation can be very distressing for patients as they persist for life, are very difficult to treat, and remain a constant reminder of prior drug usage. The difficulty of treatment is due to the location of the deposited material and its exogenous nature. Read More

Lasers Surg Med 2018 Mar 25. Epub 2018 Mar 25.

DermaLase Training Services, 120 Queens Drive, Glasgow, G42, United Kingdom.

Introduction: Dark material has been observed embedded within glass slides following Q-switched Nd:YAG laser treatment of tattoos. It appears that these fragments are ejected at high speed from the skin during the treatment.

Method: Light microscopic analysis of the slides reveals aggregates of dark fragmented material, presumably tattoo ink, with evidence of fractured/melted glass. Read More

J Dtsch Dermatol Ges 2018 Apr 9;16(4):468-470. Epub 2018 Mar 9.

Laserklinik Karlsruhe, Karlsruhe, Germany.

J Cosmet Laser Ther 2018 Nov - Dec;20(7-8):415-418. Epub 2018 Feb 28.

a Department of Cosmetic Laser Surgery , Hospital of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College , Nanjing , China.

: To retrospectively evaluate the efficacy of an Alexandrite picosecond laser versus Nd:YAG nanosecond laser for removing blue-black eyeliner tattoos which have existed more than 10 years. : A total of 40 patients were treated with an Alexandrite picosecond laser in our department from August 2015 to July 2017, with a fluence of 1.96-6. Read More

Laser Ther 2017 Dec;26(4):274-281

Kasai Clinic for Plastic Surgery.

Background And Aims: The selective removal of tattoos and benign cutaneous pigmented lesions with laser energy evolved rapidly with the development of the nanosecond-domain Q-switched laser (ns-laser). Recently, however, a series of picosecond-domain lasers (ps-lasers) with pulsewidths less than 1 ns has become commercially available, enabling more efficient and faster removal of pigmented lesions in the field of dermatologic laser surgery.

Rationale Behind The Ps-laser: The efficacy of the ns-laser depended on the theory of selective photothermolysis, whereby an extremely short pulse width was delivered less than the thermal relaxation time (TRT) of a target. Read More

Lasers Med Sci 2018 Nov 9;33(8):1827-1831. Epub 2018 Feb 9.

Dermatology Department, Laser Unit, Hospital Universitario Ramón y Cajal, Ctra Colmenar Viejo Km 9,100, 28034, Madrid, Spain.

The novel picosecond lasers, initially developed for faster tattoo removal, have also shown great efficacy in endogenous pigmentary disorders. To describe the efficacy and safety profile of an alexandrite (755-nm) picosecond laser in a wide range of pigmented flat and elevated cutaneous lesions. A retrospective study was performed in which we collected all the clinical images of patients treated with the 755-nm alexandrite picosecond laser for 12 months (November 2016-November 2017). Read More

Praxis (Bern 1994) 2018 Jan;107(3):153-157

2 Cabinet médical et Laser, Denges.

Semin Cutan Med Surg 2017 Dec;36(4):148-154

Department of Dermatology, Center of Laser medicine NRW, Bochum, Gemany.

This review describes the use of picosecond lasers for the treatment of tattoos, pigmented lesions, scars, and their use in rejuvenation. These devices have delivered enhanced efficacy for the treatment of tattoos and pigmented lesions when compared to the older 40-50 nanosecond devices. The fractional delivery with the picosecond devices have opened up a new method of rejuvenation for photodamaged skin and the treatment of scars. Read More

Ann Dermatol 2017 Dec 30;29(6):779-781. Epub 2017 Oct 30.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

The picosecond lasers have shown to effectively treat tattoo pigments that are intractable to previous multiple Q-switched (QS) laser treatments. Therefore we hypothesized that a picosecond laser would show better efficacy with minimal adverse events in the treatment of melasma and post-inflammatory hyperpigmentation (PIH) that are difficult to treat with conventional QS lasers. Two patients with melasma and one patient with PIH were treated with a Picosecond 755-nm Alexandrite Laser (Cyanosure, USA). Read More