Search Our Scientific Publications & Authors

Skeletal Radiol 2021 Jun 23. Epub 2021 Jun 23.

Department of Radiology, UC San Diego Health, 200 W. Arbor Drive, #8226, San Diego, CA, 92103, USA.

Objective: Tarsal coalition is known to cause abnormal talocrural stress, hindfoot malalignment, and ankle sprains. These can all be associated with osteochondritis dissecans (OCD) of the talar dome. We present the first detailed description of a series of talar OCDs occurring in patients with tarsal coalition, with the goal of determining whether there is an increased prevalence of OCDs among patients with tarsal coalition. Read More

Am J Med Genet A 2021 Jun 23. Epub 2021 Jun 23.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

Retinoic acid exposures as well as defects in the retinoic acid-degrading enzyme CYP26B1 have teratogenic effects on both limb and craniofacial skeleton. An initial report of four individuals described a syndrome of fetal and infantile lethality with craniosynostosis and skeletal anomalies caused by homozygous pathogenic missense variants in CYP26B1. In contrast, a 22-year-old female was reported with a homozygous missense pathogenic variant in CYP26B1 with complex multisuture craniosynostosis and intellectual disability, suggesting that in some cases, biallelic pathogenic variants of CYP26B1 may be compatible with life. Read More

Microsurgery 2021 Jun 22. Epub 2021 Jun 22.

Department of Plastic and Reconstructive Surgery, National Center for Global Health and Medicine, Tokyo, Japan.

The medial tarsal area is a commonly used donor site for skin grafts to the digits and toes, with good color and texture match as well as a concealable donor site scar. Yet, there has been no report as a perforator free flap donor site. The purpose of this report is to present a new perforator flap harvested from medial tarsal region. Read More

Rev Esp Cir Ortop Traumatol 2021 Jun 17. Epub 2021 Jun 17.

Hopital du Jura, Delémont, Suiza.

Background: The vascular anatomy of the talus attracts intense research being not always easy to understand. The high intraosseous variability together with the anatomical characteristics makes some areas of the talus more prone to vascular compromise. The aim of this study is to describe the vascularization of the talus, both intraosseous and extraosseous. Read More

Jt Dis Relat Surg 2021 11;32(2):420-427. Epub 2021 Jun 11.

Ankara Şehir Hastanesi Ortopedi ve Travmatoloji Kliniği, El ve Üst Ekstremite Cerrahisi Bölümü, 06800 Çankaya, Ankara, Türkiye.

Objectives: Calcaneal fractures are the most common tarsal fractures following a foot-ankle trauma. The Böhler's angle is an important measurable angle before, during, and after surgery. In this study, we aimed to investigate correlation between Böhler's angle, calcaneal strength, and subtalar joint stress using a finite element analysis (FEA). Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Jun;35(6):729-733

Department of Orthopedics, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu Sichuan, 610072, P.R.China.

Objective: To compare the effectiveness of robot assisted internal fixation and traditional open reduction and internal fixation for calcaneal fractures.

Methods: The clinical data of 44 patients (44 feets) with calcaneal fracture admitted between October 2017 and December 2018 who met the selection criteria were retrospectively analyzed. According to different operation methods, they were divided into trial group (19 cases, treated with robot assisted percutaneous reduction and cannulated screw fixation through tarsal sinus incision) and control group (25 cases, treated with open reduction and internal fixation via traditional tarsal sinus incision). Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Jun;35(6):722-728

Department of Spinal Surgery, the Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou Zhejiang, 310000, P.R.China.

Objective: To investigate the effectiveness of fixation the posterior malleolus or not to treat different Haraguchi's classification of posterior malleolus fractures.

Methods: The clinical data of 86 trimalleolar fracture patients who were admitted between January 2015 and September 2019 and met the selection criteria were retrospectively reviewed. There were 29 males and 57 females; the age ranged from 26 to 82 years with a mean age of 55. Read More

Ann Plast Surg 2021 Jul;87(1):12-15

From the Department of Ophthalmology, Daping Hospital, Army Medical University, Chongqing, China.

Objective: A majority of patients with senile entropion have a lower eyelid pouch. This study aimed to explore a modified method to correct the entropion and enhance ophthalmic cosmetology.

Patients And Methods: Patients with senile entropion and lower eyelid pouches, who underwent anterior fascia of tarsus tightening combined with lower eyelid pouch plastic surgery from 2018 to 2019, were enrolled in the study. Read More

J Foot Ankle Surg 2021 Apr 20. Epub 2021 Apr 20.

Department of Orthopedics, the First Hospital of China Medical University, Shenyang, Liaoning Province, China. Electronic address:

Pseudomyogenic hemangioendothelioma is a rare soft tissue tumor most often found in the lower extremities and predominantly occurring in males. The talocalcaneal coalition is an anatomic anomaly that develops between the talus and calcaneus bones, can cause hindfoot pain and subtalar joint stiffness, and has a prevalence of less than 1%. We present what is to our knowledge the first case report of a 17-year-old male with pseudomyogenic hemangioendothelioma occurring within a talocalcaneal coalition. Read More

Orphanet J Rare Dis 2021 Jun 11;16(1):270. Epub 2021 Jun 11.

Moorfields Eye Hospital, 51 North Block, 5 Chicheley Street, London, SE1 7PJ, UK.

Purpose: To evaluate the safety and preliminary efficacy of topical rVA576, a dual inhibitor of complement component 5 (C5) and leukotriene B4 (LTB4), in patients with recalcitrant atopic keratoconjunctivitis (AKC) in the open label phase 1 TRACKER clinical trial.

Methods: Three patients diagnosed with moderate or severe AKC who had been on maximal topical treatment (antihistamines and ciclosporin) for at least three months prior to entry, and showed persistent symptoms and signs of inflammation, were recruited into the trial. Patients received rVA576 eye drops twice a day for 8 weeks. Read More

J Pediatr Orthop 2021 Jul;41(Suppl 1):S39-S46

Campbell Clinic Orthopaedics, Memphis, TN.

Introduction: Hindfoot deformities in the pediatric population can be painful and result in severe limitations. Although arthrodesis is known to relieve pain, there are concerns over its use because of the risk that adjacent joint degenerative disease could result, leading to a new source of pain, dysfunction, and additional surgical procedures later in life.

Methods: A literature review of hindfoot fusions in children focused on articles with the highest levels of evidence and those of particular historical significance. Read More

Ophthalmic Plast Reconstr Surg 2021 Jun 4. Epub 2021 Jun 4.

South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia Division of Sonic Healthcare Limited, Clinpath Pathology, Mile End, South Australia, Australia Flinders Eye Centre, Bedford Park, South Australia, Australia.

We present the case of a Caucasian woman with a histology-confirmed granuloma faciale of the tarsoconjunctival surface of the eyelid. A 66-year-old female patient presented with a 1-week history of painless left upper eyelid mass without history of allergy, trauma, or ocular surgery. There was an elevated well-demarcated flesh-colored lesion within the tarsus. Read More

Saudi J Ophthalmol 2020 Jul-Sep;34(3):230-232. Epub 2021 Feb 27.

Department of Ophthalmology, Dhahran Eye Specialist Hospital, Dhahran, Saudi Arabia.

A 2-year-old girl presented with pain, itching, photophobia, and tearing in her left eye. These symptoms started after contact with a caterpillar. The patient was initially taken to another hospital, where the local ophthalmologist prescribed topical prednisolone acetate 1%, a topical antibiotic, and cyclopentolate 1% eye drops. Read More

Sci Rep 2021 Jun 2;11(1):11543. Epub 2021 Jun 2.

Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, 100044, China.

Ischyromyids are a group of large rodents with the earliest fossil record known from the late Paleocene (Clarkforkian) of North America; they are considered the earliest fossil representatives of Rodentia of modern aspect. Ischyromyids dominated early Paleogene small-mammal assemblages of North America and in the latest Paleocene migrated to western Europe and to Asia; in the latter they survived only to the beginning of the late Eocene, but were never abundant. Here we describe for the first time the calcanei of ischyromyids from the early middle Eocene of the Erlian Basin in Nei Mongol, northern China. Read More

Surv Ophthalmol 2021 May 30. Epub 2021 May 30.

Department of Ophthalmology, University of Texas Health San Antonio, San Antonio, Texas. Electronic address:

Superior limbic keratoconjunctivitis (SLK) is characterized by chronic inflammation of the limbus and superior bulbar and tarsal conjunctivae. Patients also often have fine punctate staining of the limbus and adjacent area, superior limbic proliferation seen as thickening of the limbal epithelium and surrounding conjunctiva, and occasionally filaments at the superior limbus and upper cornea. SLK frequently presents with ocular irritation, foreign body sensation, and photophobia. Read More

Injury 2021 May 17. Epub 2021 May 17.

Department of Orthopaedics, Gold Coast University Hospital, Southport, Queensland 4215 Australia. Electronic address:

Introduction: The calcaneus is the most commonly fractured hindfoot bone, accounting for over 60% of all tarsal fractures. The aim of this study was to compare the mechanism of injury and psychological health status in patients presenting with calcaneal fractures to an age- and sex-matched control group with ankle fractures.

Patients And Methods: This retrospective study was undertaken within an orthopaedic unit at a tertiary hospital. Read More

Can J Ophthalmol 2021 May 29. Epub 2021 May 29.

Department of Ophthalmology and Visual Sciences, University of Iowa, Carver College of Medicine, Iowa City, Iowa. Electronic address:

Objective: To determine if repeat Müller's muscle conjunctival resection (MMCR) is a viable approach in the treatment of recurrent or residual eyelid ptosis.

Methods: A retrospective review of patients who underwent repeat MMCR was performed using external photos obtained preoperatively, postoperatively, and at last follow-up. The marginal reflex distances (MRD1 and MRD2), brow position (BP), and tarsal platform show (TPS) were evaluated with digital image analysis. Read More

Int Orthop 2021 May 28. Epub 2021 May 28.

Department of Orthopedic Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Purpose: Our aim is to retrospectively review and evaluate the patterns of affection of Charcot arthropathy of foot and ankle.

Methods: Two hundred twenty-eight patients (235 feet) with post-acute Charcot were reviewed and classified anatomically through plain radiographs into type I and type II based on single or multiple regions affected, respectively. Type I included ankle, Lisfranc (tarsometatarsal), naviculocuneiform, forefoot, and hindfoot which includes one of the following: talonavicular joint, calcaneocuboid joint, or calcaneus. Read More

Sci Rep 2021 May 28;11(1):11678. Epub 2021 May 28.

Medical Student in Clinical Medicine, Dalian Medical University, Dalian, 116044, People's Republic of China.

Arch Rheumatol 2021 Mar 14;36(1):107-113. Epub 2021 Jan 14.

Department of Neurology, Konyang University College of Medicine, Daejeon, South Korea.

Objectives: This study aims to evaluate the frequency of tarsal tunnel syndrome (TTS) in fibromyalgia (FM) patients.

Patients And Methods: In this prospective study, we investigated paresthesia of the foot, sensory and motor deficits, atrophy of the abductor hallucis muscle, and the presence of Tinel's sign in 76 female FM patients (mean age 39.3±7. Read More

Front Vet Sci 2021 10;8:664150. Epub 2021 May 10.

Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.

Pain, temperament, fear, and anxiety can prevent safe and accurate evaluation of common neurologic reflexes in dogs. When sedation is used it is unknown how the neurological examination, and specifically patellar and withdrawal reflexes are affected, and, if present, how long any effect might last. The purpose of this study is to investigate the effect of sedation on the evaluation of select common limb spinal reflexes in healthy dogs. Read More

Zhongguo Gu Shang 2021 May;34(5):471-5

Department of Traumatology and Orthopaedics, Central Hospital of Longhua District, Shenzhen 518110, Guangdong, China.

Objective: To explore clinical effect of early incision and decompression combined with screw fixation in treating Lisfranc injury and foot osteofascial compartment syndrome.

Methods: Clinical data of 5 patients with Lisfranc injury and foot osteofascial compartment syndrome were retrospective analysized from January 2017 to December 2018, including 4 males and 1 female, aged from 19 to 62 years old. All patients were suffered from closed injuries. Read More

Zhongguo Gu Shang 2021 May;34(5):448-51

Department of Orthopaedics, General Hospital of PLA, Beijing 100853, China.

Objective: To evaluate clinical efficacy of modified kidner procedure with tendoscopy in treating painful accessory navicular.

Methods: From February 2014 to April 2019, 19 patients with painful accessory navicular were admitted, including 13 males and 6 females with a mean age of 26 years old (ranged from 14 to 58 years old), all of which were unilateral symptoms. The courses of disease ranged from 6 to 60 months. Read More

Cornea 2021 May 21. Epub 2021 May 21.

Pediatric Ophthalmology Unit, A. Meyer Children's Hospital, Florence, Italy; Pediatric Allergy Unit, A. Meyer Children's Hospital, Florence, Italy; Ophthalmology Unit, University of Florence, Florence, Italy; Centre for Public Health, Queen's University of Belfast, Northern Ireland, United Kingdom; University Eye Clinic, San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy; and Department of Clinical Science and Community Health, University of Milan, Milan, Italy; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

Purpose: The aim of this study was to evaluate the safety and efficacy of tacrolimus 0.1% eye drops in a large population of pediatric patients affected by a severe form of vernal keratoconjunctivitis (VKC) who responded poorly to cyclosporine eye drops.

Methods: This is a retrospective study based on standardized clinical charts and data collection of consecutive patients affected by severe VKC who responded poorly to cyclosporine eye drops topical treatment but treated with tacrolimus 0. Read More

Acta Ortop Mex 2020 Nov-Dec;34(6):422-425

Ortopedia y Traumatología, Hospital Ángeles Mocel. Ciudad de México. México.

Introduction: Osteoblastoma is a benign, aggressive and rare osteoblastic tumor. Its most common location is in later elements of the spine and sacrum. The cuboid presentation is exceptional. Read More

Foot Ankle Surg 2021 May 12. Epub 2021 May 12.

Annajah Medical School, Palestine. Electronic address:

Purpose: This study aims to evaluate changes in tarsal bones relationship after the use of one week accelerated Ponseti method in the treatment of severe idiopathic clubfoot using MRI. We hypothesize that one-week accelerated Ponseti is at least as effective as standard techniques in achieving the desirable MRI parameters.

Methods: This is a prospective study of 8 children with severe idiopathic clubfeet (Pirani 6) (4 unilateral and 4 bilateral) treated before the age of three months with one-week accelerated Ponseti technique, as described in a former study with minimum 2-year follow-up. Read More

BMC Musculoskelet Disord 2021 May 19;22(1):456. Epub 2021 May 19.

Department of Orthopaedics and Trauma Surgery, Schön Klinik Neustadt, Am Kiebitzberg 10, 23730, Neustadt in Holstein, Germany.

Background: Demographic changes led to an increasingly ageing population in Germany and thus to possible changes in the frequency of fractures. The primary aim of this study was to report changes in fracture rates of the lower extremities in Germany in 2002 compared to 2017 and to evaluate those changes.

Methods: Inpatient data from the German National Hospital Discharge Registry (ICD10) for 2002 and 2017 were evaluated. Read More

Comput Methods Programs Biomed 2021 Jul 24;206:106124. Epub 2021 Apr 24.

The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, China. Electronic address:

Background And Objective: Calcaneus is the largest tarsal bone to withstand the daily stresses of weight-bearing. The calcaneal fracture is the most common type in the tarsal bone fractures. After a fracture is suspected, plain radiographs should be taken first. Read More

Transl Vis Sci Technol 2021 Apr;10(5)

Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.

Purpose: Surgery is the standard treatment for floppy eyelid syndrome, but crosslinking (CXL) tarsus has recently been proposed as an alternative. To the best of our knowledge, this study is the first to use second-harmonic generation (SHG) microscopy to examine tarsal collagen ex vivo before and after photo-activated crosslinking. To quantify crosslinking, this study examined fluorescence recovery after photobleaching (FRAP), which indirectly measures tissue stiffness. Read More

Skeletal Radiol 2021 May 17. Epub 2021 May 17.

Department of Radiology, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, Middlesex, UK.

Flatfoot is commonly encountered in the paediatric population and describes a spectrum of clinical and radiological presentations which encompass both normally developing and pathological feet. Flatfoot can be categorised as flexible or rigid, a distinction which has important implications when considering the potential underlying aetiology and treatment options, and therefore imaging is an important component of the diagnostic workup. Weight-bearing plain radiographs are established initial investigations, although the significance of a number of the commonly derived quantitative parameters in children remains unclear. Read More