Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2022 Feb;34(2):158-162
Anhui Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu, Anhui 233000, China.
Objective: To investigate the protective effect of hydatid cyst fluid protein (HCFP) on ovalbumin (OVA)-induced allergic rhinitis (AR) in mice.
Methods: Twenty-four BALB/c mice at ages of 8 to 10 weeks, each weighing approximately 20 g, were randomly divided into four groups, including groups A (blank control group), B (blank intervention group), C (AR model group) and D (AR+HCFP intervention group), with 6 mice in each group. On days 0, 2, 4, 6, 8, 10 and 12, mice in groups A, B, C and D were injected with 200 μL sterile phosphate buffered saline (PBS), 200 μL sterile PBS containing 20 μg HCFP, 200 μL sterile PBS containing 50 μg OVA and 5 mg Al(OH) gel, and 200 μL sterile PBS containing 50 μg OVA, 5 mg Al(OH) gel and 20 μg HCFP, respectively. Read More