5,534 results match your criteria Takayasu Arteritis


Off-label use of tocilizumab to treat non-juvenile idiopathic arthritis in pediatric rheumatic patients: a literature review.

Pediatr Rheumatol Online J 2018 Dec 14;16(1):79. Epub 2018 Dec 14.

Department of Rheumatology, Ajou University of medical school, 164 Worldcup-ro, Yeongtong-gu, Suwon, 16499, Republic of Korea.

Tocilizumab, an anti-interleukin-6 (IL-6) agent, is indicated as a treatment for several autoimmune or inflammatory diseases, including rheumatoid arthritis and juvenile idiopathic arthritis (JIA). IL-6 plays roles in both immune system dysregulation and inflammation, and thus efforts to extend the utility of tocilizumab in patients with autoinflammatory conditions are ongoing. Here, we survey the literature on the off-label use of tocilizumab in patients with juvenile-onset rheumatic diseases including juvenile systemic lupus erythematosus (SLE), juvenile dermatomyositis (DM), vasculitis, juvenile scleroderma, and other autoinflammatory diseases. Read More

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December 2018

Coronary-carotid artery collateral formation in Takayasu's arteritis: First reported case in the literature.

J Cardiol Cases 2014 Apr 28;9(4):151-153. Epub 2014 Jan 28.

Department of Cardiology, Istanbul Medicine Hospital, İstanbul, Turkey.

We present the first case report of coronary-carotid artery collateral formation in Takayasu's arteritis. There was a vasculitic involvement of both subclavian and carotid arteries with critical stenosis; cerebral perfusion was supported with collaterals arising from the mesenteric arteries and coronary artery. < A case of coronary-carotid artery collateral formation in Takayasu's arteritis is presented. Read More

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A case of a patient with Takayasu arteritis treated with left subclavian artery stent implantation.

J Cardiol Cases 2015 Oct 8;12(4):123-125. Epub 2015 Jul 8.

Cardiology Division, Kangnam Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea.

Takayasu arteritis is an uncommon chronic inflammatory arteritis affecting large vessels, predominantly the aorta and its main branches. This disease, primarily known to be frequent in Asia and Latin America region, occurs mainly in young people between the ages of 15 and 25 years, with a male to female ratio of 1:9. Here, we report a young Asian female patient with Takayasu arteritis affecting multiple arteries and treated with percutaneous transluminal angioplasty. Read More

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October 2015

European consensus-based recommendations for the diagnosis and treatment of rare paediatric vasculitides - the SHARE initiative.

Rheumatology (Oxford) 2018 Dec 7. Epub 2018 Dec 7.

Department of Paediatric Rheumatology, Alder Hey Children's Hospital, Liverpool, UK.

Objectives: The European initiative Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) aimed to optimize care for children with rheumatic diseases. Systemic vasculitides are very rare in children. Consequently, despite recent advances, paediatric-specific information is sparse. Read More

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December 2018
4 Reads

Disease progression of Takayasu arteritis in two patients treated with tocilizumab.

Ann Rheum Dis 2018 Dec 8. Epub 2018 Dec 8.

Department of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA.

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December 2018

Update on the epidemiology, risk factors, and outcomes of systemic vasculitides.

Best Pract Res Clin Rheumatol 2018 04 2;32(2):271-294. Epub 2018 Nov 2.

Department of Rheumatology, Hospital of Bruneck, Bruneck, Italy; Department of Rheumatology and Immunology, Medical University Graz, Graz, Austria.

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and giant cell arteritis (GCA) are the most common primary systemic vasculitides of the adult population, while polymyalgia rheumatica (PMR) is a clinical syndrome often associated with GCA. Incidence and prevalence rates of AAV have been increasing in the last decades, whereas those of GCA and PMR have remained stable. The mutual interplay between environmental and genetic risk factors leading to the development of these diseases has been further analyzed in the last years. Read More

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Investigations in systemic vasculitis - The role of imaging.

Best Pract Res Clin Rheumatol 2018 02 25;32(1):63-82. Epub 2018 Sep 25.

University Hospital Gasthuisberg, Herestraat 49, B3000, Leuven, Belgium. Electronic address:

Imaging plays an increasing role for confirming a suspected diagnosis of giant cell arteritis (GCA) or Takayasu arteritis (TAK). Ultrasound, magnetic resonance imaging (MRI), and computed tomography demonstrate a homogeneous, most commonly concentric, arterial wall thickening. 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) displays increased FDG uptake of inflamed artery walls delineating increased metabolism. Read More

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February 2018

Clinical features and structured clinical evaluation of vasculitis.

Best Pract Res Clin Rheumatol 2018 02 22;32(1):31-51. Epub 2018 Nov 22.

Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom. Electronic address:

Systemic vasculitides are a group of heterogeneous conditions with overlapping patterns of clinical and laboratory manifestations. Moreover, clinical features can be non-specific and seemingly disparate. A major factor in defining optimal therapy and measuring treatment response is careful disease assessment targeting four main domains: activity, damage, prognosis and quality of life/function. Read More

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February 2018

Prognosis and future developments in vasculitis.

Best Pract Res Clin Rheumatol 2018 02 22;32(1):148-165. Epub 2018 Sep 22.

Department of Medicine, Imperial College London, United Kingdom.

The prognosis of ANCA-associated vasculitis has been transformed in recent years. Once it was a set of invariably acute and fatal conditions, but these disorders are currently considered to be chronic diseases. This change is largely attributable to earlier diagnosis and the careful application of immunotherapeutics. Read More

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February 2018

Surgical intervention and its role in Takayasu arteritis.

Authors:
Justin C Mason

Best Pract Res Clin Rheumatol 2018 02 17;32(1):112-124. Epub 2018 Aug 17.

Vascular Sciences and Rheumatology, Imperial Centre for Translational & Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK. Electronic address:

Vascular surgery remains an important option in the management of Takayasu arteritis (TA). Its use is predominantly confined to the treatment of symptomatic organ ischaemia or life-threatening aneurysm formation. In most cases, this follows the failure of medical therapy to prevent arterial injury. Read More

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February 2018

Frequency of pulmonary hypertension in transthoracic echocardiography screening is not increased in Takayasu arteritis: Experience from a single center in Turkey.

Eur J Rheumatol 2018 Dec 12;5(4):249-253. Epub 2018 Oct 12.

Division of Rheumatology, Department of Internal Medicine, Ege University School of Medicine, İzmir, Turkey.

Objective: Pulmonary hypertension (PH) may occur in Takayasu arteritis (TA), mostly due to pulmonary arteritis, but also due to left heart disease and/or chronic thromboembolism (CTE). Using transthoracic echocardiography (TTE), we investigated the frequency of PH caused by pulmonary arteritis.

Methods: This cross-sectional study included 70 patients with TA fulfilling the 1990 ACR criteria, 68 healthy controls, and 67 patients with systemic sclerosis (SSc) fulfilling the 1980 ACR criteria representing the disease control group. Read More

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December 2018
2 Reads

Takayasu Arteritis Presenting as Renovascular Hypertension and Renal Failure in a Patient with Factor VII Deficiency.

Eurasian J Med 2018 Oct;50(3):210-212

Department of Cardiology, Istanbul Medeniyet University School of Medicine, İstanbul, Turkey.

A 23-year-old female patient with factor VII (FVII) deficiency was admitted with severe hypertension and renal failure. Brachial arterial pressures were 230/120 and 220/115 mm/Hg on the right and left arms, respectively. There was no blood pressure difference between the arms. Read More

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October 2018
1 Read

Surgical correction of Takayasu's arteritis involving both coronary and pulmonary arteries.

Ann Thorac Surg 2018 Dec 1. Epub 2018 Dec 1.

Department of Thoracic and Cardiovascular Surgery, Sejong general hospital, Korea. Electronic address:

We describe a patient presenting acute heart failure due to obliteration of the bilateral coronary arteries and pulmonary arteries with Takayasu's arteritis undergoing surgical correction. The diseased vessels provoked chest pain and severe dyspnea. Urgent surgical correction successfully resolved heart failure by coronary artery bypass graft using bilateral in situ internal thoracic arteries and by patch winding of the left pulmonary artery. Read More

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December 2018
7 Reads

Pregnancy with Takayasu's Arteritis: A Case Report and Literature Review.

Cureus 2018 Sep 26;10(9):e3370. Epub 2018 Sep 26.

Obstetrics and Gynecology, Women's Wellness and Research Center/ Hamad Medical Corporation, Doha , QAT.

Takayasu's arteritis (TA) is a rare and chronic inflammatory disease of the large vessels. It affects women of reproductive age and leads to an increased risk of cardiovascular complications, such as hypertension and congestive heart failure. We are presenting a case of a pregnant woman with TA, who was seen and managed at a tertiary care institute and ultimately enjoyed a favorable outcome. Read More

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September 2018
3 Reads

Pulmonary manifestations of large, medium, and variable vessel vasculitis.

Respir Med 2018 Dec 10;145:182-191. Epub 2018 Nov 10.

University of Texas Southwestern Medical Center, Department of Pulmonary and Critical Care Medicine, United States.

The hallmark of vasculitis is autoimmune inflammation of blood vessels and surrounding tissues, resulting in an array of constitutional symptoms and organ damage. The lung is commonly targeted in the more familiar ANCA-associated small vessel vasculitidies, but large and medium vessel vasculitides, including Takayasu arteritis, giant cell arteritis, polyarteritis nodosa, Behcet's disease, and necrotizing sarcoid granulomatosis, may also feature prominent pulmonary involvement. Pulmonary manifestations of these conditions include pulmonary arterial aneurysms, pulmonary hypertension, diffuse alveolar hemorrhage, pulmonary nodules, and parenchymal infiltrates. Read More

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December 2018
1 Read

Genetic determinants and an epistasis of and HLA-B*52 in Takayasu arteritis.

Proc Natl Acad Sci U S A 2018 Nov 29. Epub 2018 Nov 29.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.

Takayasu arteritis (TAK) is a systemic vasculitis with severe complications that affects the aorta and its large branches. HLA-B*52 is an established susceptibility locus to TAK. To date, there are still only a limited number of reports concerning non-HLA susceptibility loci to TAK. Read More

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November 2018
2 Reads

The Macaroni Sign: The Pathognomonic Ultrasonography Sign of Takayasu Arteritis.

Reumatol Clin 2018 Nov 24. Epub 2018 Nov 24.

Clinical Immunology and Rheumatology Services, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Electronic address:

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November 2018
1 Read

[Relationships between the levels of serum 25-hydroxyvitamin D and interleukin-6 in patients with Takayasu's arteritis].

Zhonghua Yi Xue Za Zhi 2018 Nov;98(43):3509-3512

Department of Rheumatology and Immunology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

The main purpose of this paper is to evaluate the level of serum 25-hydroxyvitamin D (25-OH-D) and clinical significance in patients with Takayasu's Arteritis (TA). A total of 62 untreated TA patients (TA group) and 60 healthy people (control group) were enrolled. The level of serum 25-OH-D were measured and compared between groups. Read More

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November 2018
3 Reads

Management of large-vessel vasculitis.

Curr Opin Rheumatol 2019 Jan;31(1):25-31

Department of Internal Medicine, Division of Rheumatology, School of Medicine, Istanbul University - Cerrahpasa, Istanbul, Turkey.

Purpose Of Review: Glucocorticoids are the mainstay of therapy for large-vessel vasculitis, but potential toxicity and frequent relapses led to studies with nonbiologic and biologic glucocorticoid-sparing agents. The aim of this review is to discuss the recent evidence for the management of giant cell arteritis (GCA) and Takayasu arteritis (TAK).

Recent Findings: Tocilizumab proved to be a powerful glucocorticoid-sparing agent for GCA in a randomized placebo-controlled trial, whereas the trials with tocilizumab and abatacept failed to show a significant difference from placebo in relapse-free survival rate in TAK. Read More

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January 2019
2 Reads

AQP4 antibody-positive NMO spectrum disorder associated with Takayasu arteritis.

J Neurol Sci 2018 Nov 13;396:130-132. Epub 2018 Nov 13.

Department of Neurosciences, Division of Neurology, University Hospital of Geneva, Geneva, Switzerland; Neurology Clinic, Kantonsspital Aarau, Aarau, Switzerland.

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November 2018
1 Read

Posterior Subaxial Cervical Spine Screw Fixation: A Review of Techniques.

Global Spine J 2018 Oct 19;8(7):751-760. Epub 2018 Apr 19.

Columbia University Medical Center, New York, NY, USA.

Study Design: A narrative literature review.

Objectives: To review the surgical techniques of posterior screw fixation in the subaxial cervical spine.

Methods: A broad literature review on the most common screw fixation techniques including lateral mass, pedicle, intralaminar and transfacet screws was performed on PubMed. Read More

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October 2018

Pathophysiology of large vessel vasculitis and utility of interleukin-6 inhibition therapy.

Authors:
Hajime Yoshifuji

Mod Rheumatol 2018 Nov 14:1-17. Epub 2018 Nov 14.

a Department of Rheumatology and Clinical Immunology , Graduate School of Medicine, Kyoto University , 54 Shogoin Kawahara-cho, Sakyo-ku , Kyoto , 606-8507 Japan.

Takayasu arteritis (TAK) and giant cell arteritis (GCA) affect mainly large- and medium-sized arteries. In refractory cases, vascular remodeling progresses and leads to serious outcomes. Studies have demonstrated that cytokines such as interleukin (IL)-6 play crucial roles in the pathophysiology of TAK and GCA. Read More

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November 2018
6 Reads

Aortic dilatation in patients with large vessel vasculitis: A longitudinal case control study using PET/CT.

Semin Arthritis Rheum 2018 Oct 12. Epub 2018 Oct 12.

Rheumatology Unit, Azienda Unità Sanitaria Locale Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy; University of Modena and Reggio Emilia, Modena, Italy. Electronic address:

Objective: To evaluate aortic diameter and predictors of aortic dilatation using FDG-PET/CT in a longitudinally followed cohort of patients with large vessel vasculitis (LVV) compared with controls.

Methods: All consecutive patients with LVV who underwent at least 2 PET/CT scans between January 2008 and May 2015 were included. The first and last PET/CT study was evaluated by a radiologist and a nuclear medicine physician. Read More

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October 2018
3 Reads

The Two-Faced Cytokine IL-6 in Host Defense and Diseases.

Int J Mol Sci 2018 Nov 9;19(11). Epub 2018 Nov 9.

Laboratory of Immune Regulation, World Premier International Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

Interleukein-6 (IL-6), is produced locally from infectious or injured lesions and is delivered to the whole body via the blood stream, promptly activating the host defense system to perform diverse functions. However, excessive or sustained production of IL-6 is involved in various diseases. In diseases, the IL-6 inhibitory strategy begins with the development of the anti-IL-6 receptor antibody, tocilizumab (TCZ). Read More

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November 2018
1 Read

Single fraction carbon ion radiotherapy for colorectal cancer liver metastasis: A dose escalation study.

Cancer Sci 2018 Nov 11. Epub 2018 Nov 11.

National Institute of Radiological Sciences Hospital, National Institutes for Quantum and Radiological Sciences and Technology, Chiba, Japan.

Prognosis is usually grim for those with liver metastasis from colorectal cancer (CRC) who cannot receive resection. Radiation therapy can be an option for those unsuitable for resection, with carbon ion radiotherapy (CIRT) being more effective and less toxic than X-ray due to its physio-biological characteristics. The objective of this study is to identify the optimal dose of single fraction CIRT for colorectal cancer liver metastasis. Read More

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November 2018
4 Reads

Renal autotransplantation for the management of renal artery in-stent restenosis in an adult patient with Takayasu arteritis.

BMJ Case Rep 2018 Nov 8;2018. Epub 2018 Nov 8.

Department of Cardiology, PGIMER, Chandigarh, India.

Renovascular hypertension is a common clinical presentation in Takayasu arteritis (TA), when the renal arteries are involved. Although most of the patients respond to optimal antihypertensive drug therapy, certain patients with TA require percutaneous or surgical renal artery revascularisation to manage renovascular hypertension. We, hereby, present a 45-year-old woman, who had resistant hypertension secondary to in-stent restenosis (ISR) of renal artery stent in a single functioning kidney. Read More

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November 2018
6 Reads

Complex interventions of abdominal aorta and its branches in children with Takayasu arteritis: Clinical experience from a tertiary care center in north-west India.

Int J Rheum Dis 2018 Nov 5. Epub 2018 Nov 5.

Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Aim: To report our experience on complex percutaneous interventions of the abdominal aorta and its branches in six children with Takayasu arteritis (TA).

Methods: A review of records of children with TA, who underwent percutaneous interventions of the abdominal aorta and its major branches.

Results: In this analysis, we included six children with TA who underwent intervention of the abdominal aorta and its major branches. Read More

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November 2018
4 Reads

Childhood-onset Takayasu arteritis: A 15-year experience from a tertiary referral center.

Int J Rheum Dis 2018 Nov 5. Epub 2018 Nov 5.

Department of Pediatric Rheumatology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.

Aim: To describe clinical manifestations, angiographic findings, treatment, activity and damage of our Takayasu arteritis patients.

Method: The patients who met European League Against Rheumatism/Paediatric Rheumatology International Trials Organisation/Paediatric Rheumatology European Society classification criteria for childhood-onset Takayasu arteritis were reviewed in a retrospective longitudinal manner from 2002 to 2017. Extent of the disease was assessed by Disease Extent Index for Takayasu Arteritis (DEI. Read More

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November 2018
4 Reads

Nailfold videocapillaroscopy changes in Takayasu arteritis and their association with disease activity and subclavian artery involvement.

Microvasc Res 2019 Mar 31;122:1-5. Epub 2018 Oct 31.

Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Introduction: Takayasu arteritis (TA) is a large vessel vasculitis characterized by the involvement of the aorta and its branches. In the present study, the nailfold videocapillaroscopy (NVC) findings of the TA patients were evaluated and compared to healthy individuals. Additionally, the association of NVC abnormalities with disease activity and subclavian artery involvement was also investigated. Read More

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March 2019
5 Reads

Ultrasound diagnosis and follow-up of Takayasu arteritis with femoral vein involvement.

J Vasc Surg Venous Lymphat Disord 2018 Oct 29. Epub 2018 Oct 29.

Department of Ultrasound, The First Hospital of Jilin University, Changchun, China. Electronic address:

Takayasu arteritis (TA) is a form of chronic vasculitis that mainly affects the aorta and its main branches, most commonly in young female patients. The pathogenesis of the disease remains unclear, and the clinical manifestations are nonspecific. Therefore, misdiagnosis of the disease is considered to be common. Read More

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October 2018
1 Read

Nonatherosclerotic Vascular Disease in Women.

Tex Heart Inst J 2018 08 1;45(4):233-235. Epub 2018 Aug 1.

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August 2018
3 Reads

Novel Angiographic Scores for evaluation of Large Vessel Vasculitis.

Sci Rep 2018 Oct 29;8(1):15979. Epub 2018 Oct 29.

Vascular Sciences/Rheumatology, Imperial College London and Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Rd, W12 0HS, London, UK.

Arterial involvement is the cardinal feature of large-vessel vasculitis (LVV) and prevention of disease progression is the principal therapeutic goal. However, development of tools for its evaluation represents a major unmet need. To address this, a widely-applicable imaging tool for LVV, analysing arterial involvement in 17 arterial territories, has been developed and validated. Read More

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October 2018
7 Reads

Takayasu Arteritis: From Diagnosis to a Life-Threatening Complication.

Arq Bras Cardiol 2018 Oct;111(4):638-639

Centro Hospitalar de Trás-Os-Montes e Alto Douro, Hospital de Vila Real, Portugal.

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October 2018
1 Read

Cardiac Valve Involvement in Takayasu Arteritis Is Common: A Retrospective Study of 1,069 Patients Over 25 Years.

Am J Med Sci 2018 Oct 30;356(4):357-364. Epub 2018 Jun 30.

Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: Takayasu arteritis (TA) can involve the aortic root or cardiac valves, resulting in hemodynamic disorders. In this study, we focused on the prevalence and clinical characteristics of TA patients with valve regurgitation.

Materials And Methods: We retrospectively assessed the clinical data in the electronic medical records of 1,069 consecutive patients with TA admitted to Fuwai Hospital from January 1992 to August 2017. Read More

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October 2018
5 Reads

Single-Nucleotide Polymorphism of the MLX Gene Is Associated With Takayasu Arteritis.

Circ Genom Precis Med 2018 Oct;11(10):e002296

Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Japan (N.T., Y.M., Y.I., Y.S.-W., T.A., K.H., M.I.).

Background: Takayasu arteritis (TAK) is an autoimmune systemic arteritis of unknown pathogenesis. Genome-wide association studies revealed that single-nucleotide polymorphisms in the MLX gene encoding the MLX (Max-like protein X) transcription factor are significantly associated with TAK in Japanese patients. MLX single-nucleotide polymorphism rs665268 is a missense mutation causing the Q139R substitution in the DNA-binding site of MLX. Read More

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October 2018
12 Reads

[Pulmonary cavities with Takayasu arteritis: report of 3 cases and literature review].

Zhonghua Jie He He Hu Xi Za Zhi 2018 Oct;41(10):787-792

Department of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing Institute of Respiratory Medicine, Beijing 100020, China.

To analyze the clinical features of 3 cases of Takayasu arteritis(TA) with pulmonary cavities on chest computed tomography(CT). The clinical data of 3 TA patients with cavities on the chest CT who were admitted into Beijing Chaoyang Hospital were retrospectively analyzed. A literature search was performed with "Takayasu arteritis" and "pulmonary" as the key words in China Knowledge Resource Intergrated Database (CNKI) and Pubmed Database for publications from Jan 1, 2000 to Dec. Read More

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October 2018
5 Reads

Takayasu Arteritis.

Front Pediatr 2018 24;6:265. Epub 2018 Sep 24.

Service of Immunology & Rheumatology, Hospital de Pediatría "Prof. Dr. Juan P. Garrahan", Buenos Aires, Argentina.

Takayasu arteritis is an idiopathic granulomatous vasculitis of the aorta and its main branches and it constitutes one of the more common vasculitides in children. Inflammation and intimal proliferation lead to wall thickening, stenotic or occlusive lesions, and thrombosis, while destruction of the elastica and muscularis layers originates aneurysms and dissection. Carotid artery tenderness, claudication, ocular disturbances, central nervous system abnormalities, and weakening of pulses are the most frequent clinical features. Read More

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September 2018
12 Reads

Simultaneous Multi-Supra-Aortic Artery Bypass Successfully Implemented in 17 Patients with Type I Takayasu Arteritis.

Eur J Vasc Endovasc Surg 2018 Dec 11;56(6):903-909. Epub 2018 Oct 11.

Department of Vascular Surgery, Beijing Hospital, National Centre of Gerontology, Beijing, PR China; Peking Union Medical College, Chinese Academy of Medical Science, Beijing, PR China. Electronic address:

Objective: Type I Takayasu arteritis is common in Chinese patients and usually leads to cerebral ischaemia. There are limited data regarding simultaneous multi-supra-aortic artery (SMSAA) bypass in patients with type I Takayasu arteritis. The present study shares experience of using this method. Read More

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December 2018
8 Reads

Vascular calcification in patients with large-vessel vasculitis compared to patients with hyperlipidemia.

Semin Arthritis Rheum 2018 Sep 17. Epub 2018 Sep 17.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, 10 Center Drive, Building 10, Rm 216G, Bethesda, MD 20892, USA. Electronic address:

Objective: Calcification of the coronary arteries, aorta, and branch vessels can occur in both large-vessel vasculitis (LVV) and atherosclerosis. The study objective was to determine the location and amount of vascular calcification in patients with LVV versus hyperlipidemia (HLD) and to identify risk factors associated with vascular calcification in LVV.

Methods: Patients with giant cell arteritis (GCA), Takayasu's arteritis (TAK), and HLD underwent non-contrast computed tomography of the aorta and branch vessels. Read More

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September 2018
1 Read

Bilateral Vertebral Artery Dissection and Unilateral Carotid Artery Dissection in a Case of Ehlers-Danlos Syndrome Type IV.

World Neurosurg 2018 Oct 10. Epub 2018 Oct 10.

Department of Neurosurgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.

Background: Ehlers-Danlos syndrome is a rare genetic connective tissue disorders, but the vascular type (Type IV) typically poses the greatest risk to patients. We report a case of multiple cranial artery dissection, which was successfully treated with carotid artery stenting.

Case Description: A 50-year-old woman presented with recurrent severe headaches caused by bilateral vertebral artery dissections that were treated conservatively at our hospital. Read More

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October 2018
5 Reads

Case report: Takayasu arteritis in a 3-month-old Chinese girl.

Medicine (Baltimore) 2018 Oct;97(41):e12637

Shanghai Medical College, Fudan University, Shanghai, China.

Rationale: Takayasu arteritis is a rare large vessel systemic vasculitis that predominantly affects the aorta and its main branches in women of childbearing age. Due to nonspecific symptoms during the acute phase of disease, early diagnosis is still a challenge for pediatricians.

Patient Concerns: We reported a 3-month-old girl who presented with sustained elevated levels of acutephase reactants, which could not be explained by infectious diseases and malignant diseases. Read More

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October 2018
2 Reads

"Macaroni Sign" in Takayasu Arteritis.

J Cardiovasc Imaging 2018 Sep 17;26(3):186-187. Epub 2018 Sep 17.

Department of Internal Medicine, Hospital University Tidjani Damerdji, Tlemcen, Algeria.

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September 2018
2 Reads

Coral reef aorta.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:26

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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October 2018
2 Reads

Management and evaluation of pregnant women with Takayasu arteritis.

Arch Gynecol Obstet 2018 Oct 9. Epub 2018 Oct 9.

Division of Perinatology, Department of Obstetrics and Gynecology, Medical Faculty, Hacettepe University, Sıhhiye, Ankara, Turkey.

Purpose: To evaluate the clinical characteristics, obstetric/neonatal outcomes, and pregnancy complications of pregnant women with Takayasu arteritis (TA).

Methods: We retrospectively evaluated the data of 22 pregnancies of 11 patients with TA between January 1 2000, and December 31 2017. Patient characteristics, severity of disease, obstetric outcomes, pregnancy complications, mode of delivery, and neonatal outcomes were evaluated. Read More

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October 2018
5 Reads

[Association between platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio with disease activity in Takayasu arteritis patients].

Zhonghua Xin Xue Guan Bing Za Zhi 2018 Sep;46(9):713-718

Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.

To explore the relation between platelet-to-lymphocyte ratio (PLR) or neutrophil-to-lymphocyte ratio (NLR) with disease activity in Takayasu arteritis (TA) patients. Present retrospective study involved 289 patients with TA, who were hospitalized in our department between January 2010 and October 2017, and 280 age and gender matched healthy controls,who underwent thealth examination in our health examination center during the same period (control group). TA patients were further divided into active and inactive groups (180 and 109 cases respectively) according to Kerr scores. Read More

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September 2018
2 Reads

Response to: 'Aortic ulceration in a tocilizumab-treated patient with Takayasu arteritis' by Liebling .

Ann Rheum Dis 2018 Oct 3. Epub 2018 Oct 3.

Department of Vascular Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan

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October 2018
3 Reads

Mortality and causes of death across the systemic connective tissue diseases and the primary systemic vasculitides.

Rheumatology (Oxford) 2018 Oct 3. Epub 2018 Oct 3.

Department of Rheumatology, University of Oslo, Oslo, Norway.

Objectives: Studies assessing relative mortality risks across the spectrum of systemic inflammatory rheumatic diseases are largely missing. In this study, we wanted to estimate standard mortality ratios (SMRs) and causes of death in an ethnically homogeneous cohort covering all major CTDs and primary systemic vasculitides (PSVs).

Methods: We prospectively followed all incident CTD and PSV cases included in the Norwegian CTD and vasculitis registry (NOSVAR) between 1999 and 2015. Read More

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October 2018
4 Reads

Restoration of vision by endovascular revascularization in Takayasu arteritis: A case series.

J Cardiol Cases 2018 Oct 12;18(4):123-127. Epub 2018 Jul 12.

Department of Cardiology, GB Pant Institute of Postgraduate Medical Education and Research, Maulana Azad Medical College, New Delhi 110002, India.

Takayasu arteritis (TA) is a rare, inflammatory vasculitis affecting aorta and its branches. Stenotic occlusive lesions of multiple arch arteries can cause severe cerebral ischemia leading to impaired vision. We present three consecutive young patients of TA with severe diminution of vision on upright posture, where we attempted restoration of sight by improving cerebral blood flow by percutaneous endovascular revascularization. Read More

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October 2018
4 Reads

Takayasu's aorto-arteritis: Not your regular lesion for angioplasty.

Ann Pediatr Cardiol 2018 Sep-Dec;11(3):312-314

Department of Pediatrics, ESIC Model Hospital, Ludhiana, Punjab, India.

We report a case of a 6-year-old female child with Takayasu's aorto-arteritis (TA) with severe coarctation of the aorta which resulted in an aortic dissection post-ballooning. This happened despite ensuring that markers for disease activity were negative, with appropriate corticosteroid therapy started before the procedure, and using a low-profile, low-pressure, and slightly undersized balloon for dilating the stenotic segment. It required immediate endovascular stenting to tide over the crisis. Read More

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October 2018
3 Reads

Simultaneous Multiple Bypass for Takayasu Arteritis.

Authors:
Byung-Boong Lee

Eur J Vasc Endovasc Surg 2018 Dec 26;56(6):910. Epub 2018 Sep 26.

George Washington University, Washington DC, USA; Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Electronic address:

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December 2018
1 Read