970 results match your criteria Syringoma

Four calcium signaling pathway-related genes were upregulated in microcystic adnexal carcinoma: transcriptome analysis and immunohistochemical validation.

World J Surg Oncol 2022 May 4;20(1):142. Epub 2022 May 4.

Department of Pathology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, No. 32, West Second Section, First Ring Road, Chengdu, 610072, China.

Background: Microcystic adnexal carcinoma (MAC) is a skin cancer with challenges in diagnosis and management. This study was aimed to detect molecular alterations of MAC and guide its pathologic diagnosis and treatment.

Methods: We performed transcriptome analysis on 5 MAC and 5 normal skin tissues, identified the differentially expressed genes, and verified them by immunohistochemistry. Read More

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Clear cell syringoma: Disappearance of clear cells after improvement in diabetes mellitus by pituitary adenoma resection.

J Dermatol 2022 Apr 24. Epub 2022 Apr 24.

Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

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Chondroid Syringoma: an asymptomatic benign tumour.

Ital J Dermatol Venerol 2022 Mar 11. Epub 2022 Mar 11.

Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy -

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Mixed tumour of the skin of the lower lip: A case report and review of the literature.

Mol Clin Oncol 2022 Mar 24;16(3):69. Epub 2022 Jan 24.

Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa 903-0215, Japan.

Mixed tumour of the skin or chondroid syringoma (CS) is a rare and mostly benign neoplasm of the sweat glands. Although CS is frequently located on varied parts of the head and neck region, the lower lip is a rarely reported site. The present report describes a case of CS of the lower lip in a 58-year-old male as an expository case to further emphasise the need for proper diagnosis, appropriate treatment and prognostic evaluation. Read More

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Chondroid syringoma with osteoma cutis.

JAAD Case Rep 2022 Apr 31;22:2-4. Epub 2022 Jan 31.

Department of Dermatology, Hospital Corporation of America Healthcare/University of South Florida Morsani College of Medicine GME: Largo Medical Center, Largo, Florida.

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Absence of TFE3 Immunoexpression in a Spectrum of Cutaneous Mixed Tumors: A Retrospective Pilot Study.

Dermatopathology (Basel) 2022 Jan 29;9(1):48-53. Epub 2022 Jan 29.

Department of Pathology and Laboratory Medicine, University of Rochester Medical Center (URMC), Rochester, NY 14642, USA.

Background: Cutaneous mixed tumors (CMTs) include benign, atypical, and malignant chondroid syringomas. This spectrum of entities is known to be a part of myoepithelial neoplasms, which display considerable genetic heterogeneity. In a previous report, a malignant chondroid syringoma (MCS) demonstrated PHF1-TFE3 gene fusion and strong TFE3 immunohistochemical (IHC) staining. Read More

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January 2022

Recent Advances on Immunohistochemistry and Molecular Biology for the Diagnosis of Adnexal Sweat Gland Tumors.

Cancers (Basel) 2022 Jan 18;14(3). Epub 2022 Jan 18.

French Network of Rare Skin Cancers, CARADERM, France.

Cutaneous sweat gland tumors are a subset of adnexal neoplasms that derive or differentiate into the sweat apparatus. Their great diversity, rarity, and complex terminology make their pathological diagnosis challenging. Recent findings have revealed a wide spectrum of oncogenic drivers, several of which are of diagnostic interest for pathologists. Read More

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January 2022

Comment on: Eruptive Syringoma - Two Cases with Dermoscopic Features.

Skin Appendage Disord 2022 Jan 18;8(1):81-82. Epub 2021 Aug 18.

Department of Dermatology, Lusiada University Fundation, Sao Paulo, Brazil.

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January 2022

Proptosis Revealing a Rare Lacrimal Gland Tumor: A Case of Chondroid Syringoma in a 35-year-old Patient.

Clin Pathol 2022 Jan-Dec;15:2632010X211070777. Epub 2022 Jan 9.

Faculty of Health Sciences, Abdou Moumouni University, Niamey, Niger.

Lacrimal gland chondroid syringoma is a very rare tumor with classic clinico-radiological symptoms that should be familiar to clinicians for appropriate patients' management as the tumor has potential for recurrence and malignant transformation. We report herein a case of chondroid syringoma in a 35-year-old patient presenting with progressive painless proptosis for 2 years. He underwent complete surgical removal of the tumor, with subsequent clinical improvement of his symptoms. Read More

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January 2022

[The most common benign cutaneous neoplasms of the epidermis and appendages and their treatment].

Hautarzt 2022 Feb 5;73(2):94-103. Epub 2022 Jan 5.

Colentina Krankenhaus, Abt. Dermatology II, "Carol Davila"-Universität für Medizin und Pharmazie, Bukarest, Rumänien.

Benign cutaneous neoplasms are well defined histologically with absence of all of the following features: architectural disorder, necrosis, cytologic atypia, and atypical mitotic figures. The clinical appearance of any neoplasm is a very important diagnostic factor. The classification of the lesion determines the therapeutic options. Read More

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February 2022

Vulvar syringomas.

Proc (Bayl Univ Med Cent) 2022 30;35(1):113-114. Epub 2021 Sep 30.

Department of Dermatology, Baylor Scott & White Medical Center - Temple, Temple, Texas.

Syringomas on the vulvar skin are relatively rare and generally bilateral. They are usually asymptomatic but can be symptomatic, with vulvar discomfort, burning, and/or pruritus. Management options include topical steroids, topical retinoids, and oral antihistamines. Read More

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September 2021

Isolated eyelid chondroid syringoma: a study of two cases.

BMJ Case Rep 2021 Dec 30;14(12). Epub 2021 Dec 30.

Ocular Oncology Services, The Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, Telangana, India

Chondroid syringoma is a benign mixed tumour arising from the sweat glands which can be apocrine (found throughout the surface of the eyelid) or eccrine with a mean age of presentation being 50 years. Here we report two cases of chondroid syringoma of the upper eyelid, one in a young male patient and the other in an elderly woman. Both cases had well-defined lesions involving upper eyelid in the sub-brow region, underwent excisional biopsy, and histopathological findings were consistent with an apocrine type of chondroid syringoma in one case and eccrine type of chondroid syringoma in the second case. Read More

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December 2021

Dermoscopy of Eruptive Syringoma.

Skin Appendage Disord 2021 Aug 22;7(5):401-403. Epub 2021 Apr 22.

Division of Dermatology, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

Syringoma is a benign adnexal tumor of eccrine origin. Eruptive syringoma (ES) is a rare variant and can mimic other diseases especially lichen planus (LP). The dermoscopic observation of ES is not well described. Read More

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An Unusual Case of Genital Lesion: A Vulvar Syringoma.

J Family Reprod Health 2021 Mar;15(1):70-73

Department of Obstetrics and Gynaecology, Locatelli Hospital, ASST Bergamo est, Piario, Bergamo, Italy.

Syringoma is a benign adnexal neoplasm of sweat gland, usually presenting as extra-genital lesions, while vulvar localization is rare. Moreover, syringoma is an uncommon vulvar neoplasms. A 44-year-old woman with previous diagnosis of duodenal gastrointestinal stromal tumour, underwent a local surgical excision for an isolated, painful, vulvar lesion. Read More

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Large chondroid syringoma in the reconstructed nasal tip: Diagnostic dilemmas and surgical management.

JAAD Case Rep 2021 Sep 24;15:39-41. Epub 2021 Jul 24.

Department of Otolaryngology and Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

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September 2021

Generalized Eruptive Syringoma in a Nigerian Woman: A Case Report and a Brief Literature Review.

H Yahya

Niger J Clin Pract 2021 Aug;24(8):1252-1254

Dermatology Unit, Department of Internal Medicine, Kaduna State University/Barau Dikko Teaching Hospital, Kaduna, Nigeria.

Generalized eruptive syringomas are a very rare variant of syringoma which appear on the chest, neck, abdomen, upper and lower arms, thighs, legs and back. They often affect adolescent or post-adolescent females, although cases have been described in children and older adults. Generalized eruptive syringomas are mostly sporadic but familial cases, and those associated with eczematous skin conditions, solid organ transplants, renal cell carcinoma and some genodermatoses have also been reported. Read More

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Incidental syringomatous proliferation: A benign, subclinical finding during Mohs micrographic surgery.

JAAD Case Rep 2021 Aug 2;14:127-129. Epub 2021 Jul 2.

Department of Dermatology, University of California Davis School of Medicine, Sacramento, California.

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Incidental Clear Cell Syringoma of the Scalp in a Patient With Lichen Planopilaris.

Cureus 2021 Jun 30;13(6):e16064. Epub 2021 Jun 30.

Dermatology, San Diego Family Dermatology, National City, USA.

Syringomas are benign neoplasms of eccrine ducts; glycogen accumulation in the tumor cell cytoplasm results in a clear cell variant of syringoma. Syringoma and syringomatous proliferations (secondary to alteration of the eccrine sweat ducts) have been observed, albeit uncommonly, as an incidental finding in areas of alopecia on the scalp. A 71-year-old woman with scalp hair loss caused by lichen planopilaris had subclinical clear cell syringoma discovered as an incidental observation on evaluation of the biopsy specimen from an area of hair loss. Read More

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Chondroid syringoma: an unusual presentation in a 7-year-old boy.

BMJ Case Rep 2021 Jul 26;14(7). Epub 2021 Jul 26.

Plastic Surgery Department, Swansea Bay University Health Board, Port Talbot, UK.

Coined in 1961 by Hirsch and Helwig, the term chondroid syringoma refers to a rare mixed tumour of subcutaneous tissue. Histologically, these tumours are almost identical to pleomorphic adenomas, arising from salivary glands. With the obvious difference being the presence of sweat gland tissue (syringoma) within a matrix of cartilage (chondroid). Read More

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sQUIZ your knowledge! Asymptomatic vulvar nodules: check for tadpoles!

Eur J Dermatol 2021 Jun;31(3):442-444

Dermatology Department, Université de Tours, CHU de Tours, Avenue de la République, 37170 Chambray-les-Tours, France.

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Malignant mixed tumor of the skin on the anterior chest.

Jpn J Clin Oncol 2021 Oct;51(10):1597-1598

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

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October 2021

Solitary Reactive Eccrine Duct Proliferation with Prominent Lymphoid Infiltrates (Pseudolymphomatous Syringoma?).

Indian J Dermatol 2021 Mar-Apr;66(2):225

Department of Dermatology, Faculty of Medicine, Kagawa University, Takamatsu, Japan. E-mail:

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Cytodiagnosis of chondroid syringoma-Series of three cases.

Diagn Cytopathol 2021 Sep 26;49(9):E374-E377. Epub 2021 Jun 26.

Department of Pathology, Bhagat Phool Singh Government Medical College, Khanpur Kalan, India.

Chondroid syringoma is a rare, benign, appendegeal neoplasm. It was initially termed as mixed tumor as it comprises both epithelial cells and chondromyxoid stroma. It usually presents as a slow growing, solitary, painless, subcutaneous, or intracutaneous mass, frequently in the head and neck region. Read More

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September 2021

Giant chondroid syringoma on the upper lip: a case report.

Dermatol Online J 2021 May 15;27(5). Epub 2021 May 15.

Hospital de Especialidades, CMN SXXI, IMSS, Ciudad de México.

Chondroid syringoma is a benign, rare, asymptomatic, slow-growing mixed tumor. Tumors larger than 3cm are considered giant and may be malignant. We present a 65-year-old man with a chronic, indolent, subcutaneous tumor with upper lip deformity. Read More

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A Case Study and Review of Literature of Eruptive Syringoma in a Six-Year-Old.

Cureus 2021 Apr 22;13(4):e14634. Epub 2021 Apr 22.

Department of Pathology and Laboratory Medicine, Vidant Medical Center/East Carolina University, Greenville, USA.

Syringomas are benign tumors originating from the intraepidermal portion of eccrine sweat ducts. A six-year-old African American female presented with multiple 2-3 mm hyperpigmented papules over the neck, upper chest, and axillae bilaterally. The lesions were non-tender, non-pruritic, and did not bleed when lightly scraped. Read More

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Chondroid Syringoma of the Thenar Eminence in a US Veterans Administration (VA) Patient.

Eplasty 2021 11;21:ic4. Epub 2021 May 11.

Memphis Veterans Administration Medical Center (VAMC), Memphis, Tenn; and University of Tennessee Health Science Center (UTHSC), Memphis.

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Syringoma Localized to the Umbilicus.

Ann Dermatol 2020 Oct 29;32(5):434-436. Epub 2020 Sep 29.

Department of Dermatology, Jeonbuk National University Medical School, Jeonju, Korea.

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October 2020

An alternative for the treatment of vulvar syringoma: 577 nm pro-yellow laser.

J Cosmet Dermatol 2021 Dec 6;20(12):3931-3933. Epub 2021 May 6.

Gazi University Faculty of Medicine Department of Dermatology Emeritus Professor, Ankara, Turkey.

Background: Syringoma is a benign sweat gland tumor.

Aim: Vulvar location of syringoma is rare. Although the lesions are asymptomatic, it requires treatment due to the cosmetic concerns. Read More

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December 2021

Syringocystadenoma Papilliferum of the middle ear: Common tumor at rare site.

Indian J Pathol Microbiol 2021 Apr-Jun;64(2):426-427

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

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October 2021

A papulonodule on the nasolabial fold.

JAAD Case Rep 2021 Apr 6;10:50-52. Epub 2021 Feb 6.

Department of Pathology, University of Vermont Medical Center, Burlington, Vermont.

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