Bilateral sole hyperkeratosis and nonhealing foot mass.
JAAD Case Rep 2018 May 30;4(4):286-288. Epub 2018 Mar 30.
Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
Search our Database of Scientific Publications and Authors
Extended screening for infectious diseases among newly-arrived asylum seekers from Africa and Asia, Verona province, Italy, April 2014 to June 2015.
- Authors:
- Dora Buonfrate,
- Federico Gobbi,
- Valentina Marchese,
- Chiara Postiglione,
- Geraldo Badona Monteiro,
- Giovanni Giorli,
- Giuseppina Napoletano,
- Zeno Bisoffi
Euro Surveill 2018 Apr;23(16)
Centre for Tropical Diseases (CTD), Sacro Cuore Hospital, Negrar, Verona, Italy.
Background and aimManagement of health issues presented by newly-arrived migrants is often limited to communicable diseases even though other health issues may be more prevalent. We report the results of infectious disease screening proposed to 462 recently-arrived asylum seekers over 14 years of age in Verona province between April 2014 and June 2015. Screening for latent tuberculosis (TB) was performed via tuberculin skin test (TST) and/or QuantiFERON-TB Gold in-tube assay and/or chest X-ray. Read More
[[Response to "Congenital syphilis in the state of Baja California"]].
Salud Publica Mex 2018 Jan-Feb;60(1):99-100
Jurisdicción Tijuana, Instituto de Servicios de Salud de Baja California, Coordinación de Vigilancia Epidemiológica. México.
[[Congenital syphilis in the state of Baja California]].
- Authors:
- Carlos Jesús Conde-González
Salud Publica Mex 2018 Jan-Feb;60(1):99
Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, México.
Risk factors and incidence of syphilis in HIV-infected persons, the HIV Outpatient Study, 1999-2015.
- Authors:
- Richard M Novak,
- Abdelhamid Ghanem,
- Rachel Hart,
- Douglas Ward,
- Carl Armon,
- Kate Buchacz,
Clin Infect Dis 2018 Apr 24. Epub 2018 Apr 24.
Centers for Disease Control and Prevention, Atlanta, GA, USA.
Background: Since 2000, the incidence of syphilis has been increasing, especially among gay, bisexual and other men who have sex with men (MSM) in the United States (U.S.). Read More
Acute pustular eruption following a Jarisch-Herxheimer reaction in the treatment of syphilis.
- Authors:
- Rachel L Giesey,
- Gregory R Delost,
- Timmie R Sharma,
- Kevin D Cooper
JAAD Case Rep 2018 Apr 6;4(3):259-261. Epub 2018 Mar 6.
Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Syphilis at age 15 years.
- Authors:
- Jacqueline Kaufman,
- Bogar Garcia,
- Shawn Horrall
Proc (Bayl Univ Med Cent) 2018 Jan 1;31(1):105-106. Epub 2018 Feb 1.
Department of Emergency Medicine, Baylor Scott & White Memorial Hospital, Temple, Texas.
We present a case of a 15-year-old girl who presented with 1 month of worsening nonpruritic rash limited to her palms and soles. She had been treated twice for sexually transmitted infections. With her presentation of a nonpruritic rash on the palms and soles, a diagnosis of syphilis must be considered. Read More
A cavernous sinus lesion clinically responsive to steroids.
- Authors:
- M W Ruff,
- I D Carabenciov,
- D R Johnson,
- B E Pollock,
- J E Parisi,
- J P Klaas
J Clin Neurosci 2018 Apr 20. Epub 2018 Apr 20.
Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA. Electronic address:
Tolosa Hunt syndrome (THS) is characterized by painful ophthalmoplegia secondary to idiopathic granulomatous inflammation of the cavernous sinus. The characteristic finding on MRI is an enhancing T1 isointense and T2 hypo- or hyperintense cavernous sinus mass lesion, which may result in focal narrowing of the ipsilateral internal carotid artery. Although the incidence is quite rare, it is a common diagnostic consideration in cases that present with multiple cranial neuropathies. Read More
A Case of Ceftriaxone-Induced Acute Generalized Exanthematous Pustulosis/Generalized Pustular Psoriasis Overlap.
- Authors:
- Jianfeng Zheng,
- Yunlu Gao,
- Xuemei Yi,
- Yangfeng Ding
Case Rep Dermatol 2018 Jan-Apr;10(1):69-75. Epub 2018 Mar 27.
Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, China.
Acute generalized exanthematous pustulosis, characterized by subcorneal or superficial intraepidermal pustules, is induced by drugs in more than 90% of cases. Psoriasis is an autoimmune disease triggered by different conditions in genetically susceptible people. Generalized pustular psoriasis is an acute and severe clinical form of psoriasis, which usually occurs in patients with psoriasis undergoing aggravating factors. Read More
HIV seroprevalence, self-reported STIs and associated risk factors among men who have sex with men: a cross-sectional study in Rwanda, 2015.
- Authors:
- Roman Saba Ntale,
- Gad Rutayisire,
- Pierre Mujyarugamba,
- Eliah Shema,
- Jane Greatorex,
- Simon David William Frost,
- Pontiano Kaleebu
Sex Transm Infect 2018 Apr 21. Epub 2018 Apr 21.
Uganda Virus Research Institute, Entebbe, Uganda.
Objectives: In many populations, men who have sex with men (MSM) are at a high risk of HIV infection. This study aimed to estimate the burden of HIV, other STIs and risk behaviours among Rwandan MSM.
Methods: In this cross-sectional study, we recruited through peer referral men aged between 18 and 60 years, who reported sex with men at least once in the 12 months prior to the survey. Read More
Methods: In this cross-sectional study, we recruited through peer referral men aged between 18 and 60 years, who reported sex with men at least once in the 12 months prior to the survey. Read More
Sexually transmitted diseases of the anus and rectum: Causal agents, coinfections, HIV infection and high-risk sexual behaviour.
- Authors:
- Daniel Morgado-Carrasco,
- Mercè Alsina Gibert,
- Jordi Bosch Mestres,
- Miriam Álvarez Martínez,
- José Luís Blanco Arévalo,
- Irene Fuertes de Vega
Med Clin (Barc) 2018 Apr 18. Epub 2018 Apr 18.
Servicio de Dermatología, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, España. Electronic address:
Introduction And Objective: Sexually transmitted infections of the rectum and anus (STI-RA) mainly affect men who have sex with men (MSM). The incidence of STI-RA among them has increased in recent years.
Material And Methods: Retrospective study in patients with diagnoses of STI-RA in an STI unit during the years 2014 and 2015. Read More
Material And Methods: Retrospective study in patients with diagnoses of STI-RA in an STI unit during the years 2014 and 2015. Read More
Point-of-care tests for syphilis and yaws in a low-income setting - A qualitative study of healthcare worker and patient experiences.
- Authors:
- Michael Marks,
- Tommy Esau,
- Rowena Asugeni,
- Relmah Harrington,
- Jason Diau,
- Hilary Toloka,
- James Asugeni,
- Eimhin Ansbro,
- Anthony W Solomon,
- David Maclaren,
- Michelle Redman-Maclaren,
- David C W Mabey
PLoS Negl Trop Dis 2018 Apr 19;12(4):e0006360. Epub 2018 Apr 19.
Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London, United Kingdom.
Introduction: The human treponematoses comprise venereal syphilis and the three non-venereal or endemic treponematoses yaws, bejel, and pinta. Serological assays remain the most common diagnostic method for all treponemal infections. Point-of-care tests (POCTs) for syphilis and yaws allow testing without further development of infrastructure in populations where routine laboratory facilities are not available. Read More
Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis.
- Authors:
- Cassandra C Lautredou,
- Joshua S Hardin,
- John R Chancellor,
- Sami H Uwaydat,
- Abdallah A Ellabban,
- Ahmed B Sallam
Case Rep Ophthalmol Med 2018 19;2018:7419823. Epub 2018 Feb 19.
Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Purpose: To report the successful utilization of adjunctive repeat intravitreal corticosteroid therapy for the treatment of cystoid macular edema in syphilis-related uveitis.
Methods/patients: An HIV-positive patient with treated ocular syphilis who developed refractory cystoid macular edema (CME) was treated with repeat intravitreal corticosteroid therapy including dexamethasone intravitreal implants.
Results: Treatment led to the resolution of CME and improvement in visual acuity. Read More
Methods/patients: An HIV-positive patient with treated ocular syphilis who developed refractory cystoid macular edema (CME) was treated with repeat intravitreal corticosteroid therapy including dexamethasone intravitreal implants.
Results: Treatment led to the resolution of CME and improvement in visual acuity. Read More
Syphilis-Related Eye Disease Presenting as Bilateral Papilledema, Retinal Nerve Fiber Layer Hemorrhage, and Anterior Uveitis in a Penicillin-Allergic Patient.
- Authors:
- Jamie Dietze,
- Shane Havens
Case Rep Infect Dis 2018 18;2018:2840241. Epub 2018 Feb 18.
University of Nebraska Medical Center, S. 42nd and Emile St., Omaha, NE, USA.
. is known as the "great masquerader" for its many presentations and ocular findings in patients who are infected and develop secondary and tertiary stage of syphilis. Syphilitic ocular manifestations include uveitis, chorioretinitis, retinitis, vasculitis, vitritis, and panuveitis all with or without decreased visual acuity. Read More
HIV, syphilis and behavioral risk factors among men who have sex with men in a drug-using area of southwestern China: Results of 3 cross-sectional surveys from 2013 to 2015.
- Authors:
- Lan Guanghua,
- Chen Yi,
- Tang Shuai,
- Shen Zhiyong,
- Tang Zhenzhu,
- Ruan Yuhua,
- Mohammed Adnan Yousuf,
- Fan Wensheng
Medicine (Baltimore) 2018 Apr;97(16):e0404
Department of Health Services Administration, Florida International University, Miami, FL.
To assess human immunodeficiency virus (HIV), syphilis, and behavioral risk factors among men who have sex with men (MSM) in southwestern China, where HIV started as a drug-driven epidemic, and shifted to mainly heterosexual transmission.These cross-sectional studies were conducted yearly in 2013, 2014, and 2015 in Guangxi, China. A total of 1,996, 1,965, and 1,697 participants were recruited in 2013, 2014, and 2015, respectively. Read More
Lymphogranuloma venereum genovar L2b concomitantly with syphilis and hepatitis C in a male patient in Poland – case report
- Authors:
- Agnieszka Beata Serwin,
- Marta Koper,
- Magnus Unemo
Przegl Epidemiol 2018 ;72(1):45-51
WHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Ӧrebro University, Ӧrebro,Sweden
We describe the first case of lymphogranuloma venereum (LGV) in Poland, with inguino-femoral lymphadenopathy, diagnosed and successfully treated according to the 2013 European LGV guideline. Chlamydia trachomatis genovar L2b, mainly responsible for the ongoing LGV epidemics among men who have sex with men (MSM) in Western European countries, was confirmed. The case also verified that co-infections with other sexually transmitted infections (syphilis and hepatitis C virus) are frequent in MSM LGV patients, as well as the very large difficulties with contact tracing for these patients. Read More
Test Cost and Test Accuracy in Clinical Laboratories in Kampala, Uganda.
- Authors:
- Timothy K Amukele,
- Robert Jones,
- Ali Elbireer
Am J Clin Pathol 2018 Apr;149(6):522-529
Department of Medicine, Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD.
Objectives: To assess the accuracy and costs of laboratory tests in Kampala, Uganda.
Methods: A random selection of 78 laboratories tested external quality assurance samples at market rates. There were 40 moderate- to high-complexity and 38 low-complexity laboratories. Read More
Methods: A random selection of 78 laboratories tested external quality assurance samples at market rates. There were 40 moderate- to high-complexity and 38 low-complexity laboratories. Read More
Women infected with HIV and the impact of associated sexually transmitted infections.
Int J Gynaecol Obstet 2018 Apr 14. Epub 2018 Apr 14.
Obstetrics and Gynecology Department Sector of Infectious Diseases in Obstetrics and Gynecology, Clinical Hospital of the Federal University of Paraná, Curitiba, Paraná, Brazil.
Objective: To review the relationship between concomitant sexually transmitted infections in women infected with HIV.
Methods: PubMed and Scopus were searched for articles published in English and Portuguese between January 1, 1994, and December 31, 2015, using relevant keywords, including AIDS, HIV, female genital diseases, and sexually transmitted infections. Articles that associated sexually transmitted infections with HIV-infected women were selected for inclusion. Read More
Methods: PubMed and Scopus were searched for articles published in English and Portuguese between January 1, 1994, and December 31, 2015, using relevant keywords, including AIDS, HIV, female genital diseases, and sexually transmitted infections. Articles that associated sexually transmitted infections with HIV-infected women were selected for inclusion. Read More
Akt, mTOR and NF-κB pathway activation in Treponema pallidum stimulates M1 macrophages.
- Authors:
- Li-Rong Lin,
- Zheng-Xiang Gao,
- Yong Lin,
- Xiao-Zhen Zhu,
- Wei Liu,
- Dan Liu,
- Kun Gao,
- Man-Li Tong,
- Hui-Lin Zhang,
- Li-Li Liu,
- Yao Xiao,
- Jian-Jun Niu,
- Fan Liu,
- Tian-Ci Yang
Int Immunopharmacol 2018 Apr 12;59:181-186. Epub 2018 Apr 12.
Zhongshan Hospital, Medical College of Xiamen University, Xiamen 361004, China; Institute of Infectious Disease, Medical College of Xiamen University, Xiamen 361004, China. Electronic address:
The polarization of macrophages and the molecular mechanism involved during the early process of syphilis infection remain unknown. This study was conducted to explore the influence of Treponema pallidum (T. pallidum) treatment on macrophage polarization and the Akt-mTOR-NFκB signaling pathway mechanism involved in this process. Read More
100 years of STIs in the UK: a review of national surveillance data.
- Authors:
- Hamish Mohammed,
- Paula Blomquist,
- Dana Ogaz,
- Stephen Duffell,
- Martina Furegato,
- Marta Checchi,
- Neil Irvine,
- Lesley A Wallace,
- Daniel Rhys Thomas,
- Anthony Nardone,
- J Kevin Dunbar,
- Gwenda Hughes
Sex Transm Infect 2018 Apr 13. Epub 2018 Apr 13.
Public Health England, London, UK.
Objectives: The 1916 Royal Commission on Venereal Diseases was established in response to epidemics of syphilis and gonorrhoea in the UK. In the 100 years since the Venereal Diseases Act (1917), the UK has experienced substantial scientific, economic and demographic changes. We describe historical and recent trends in STIs in the UK. Read More
A Surprising Diagnosis: Syphilitic Gastritis and Hepatitis.
- Authors:
- Christian L Horn,
- Seyed Jalali,
- Joel Abbott,
- Michael T Stein
Am J Med 2018 Apr 10. Epub 2018 Apr 10.
Madigan Army Medical Center, Tacoma, WA.
From in vivo to in vitro: How the Guatemala STD Experiments Transformed Bodies Into Biospecimens.
- Authors:
- Kayte Spector-Bagdady,
- Paul A Lombardo
Milbank Q 2018 Apr 13. Epub 2018 Apr 13.
Center for Law, Health and Society, Georgia State University College of Law.
Policy Points: While most scholarship regarding the US Public Health Service's STD experiments in Guatemala during the 1940s has focused on the intentional exposure experiments, secondary research was also conducted on biospecimens collected from these subjects. These biospecimen experiments continued after the Guatemala grant ended, and the specimens were used in conjunction with those from the Tuskegee syphilis experiments for ongoing research. We argue there should be a public accounting of whether there are still biospecimens from the Guatemala and Tuskegee experiments held in US government biorepositories today. Read More
Sexually Transmitted Infection Prevalence in Women with HIV: Is There a Role for Targeted Screening?
Sex Transm Dis 2018 Apr 10. Epub 2018 Apr 10.
Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama.
Background: Rates of sexually transmitted infections (STI) and HIV are highest in the southern U.S., but vary widely by gender, age and risk behavior. Read More
CDC Syphilis Summit: Difficult Clinical and Patient Management Issues.
- Authors:
- Christina M Marra,
- Khalil Ghanem
Sex Transm Dis 2018 Apr 10. Epub 2018 Apr 10.
University of Washington School of Medicine, Seattle, Washington.
Despite over a century of clinical experience in diagnosing and managing patients with syphilis, many thorny clinical questions remain unanswered. We focus on several areas of uncertainty for the clinician: the role of serological tests in diagnosing syphilis and assessing syphilis treatment responses, and the risk of neurosyphilis and ocular syphilis in patients with syphilis. We also address whether clinical approaches should differ in patients who are, and are not, infected with HIV. Read More
Case for diagnosis. Atypical genital lesion.
- Authors:
- José Carlos Gomes Sardinha,
- Mauro Cunha Ramos,
- Antonio Pedro Mendes Schettini,
- Sinesio Talhari
An Bras Dermatol 2018 Jan-Feb;93(1):143-144
Service of Sexually Transmitted Infection - Fundação Alfredo da Matta (FUAM) - Manaus (AM), Brazil.
We present a case of a penile lesion with a clinical appearance similar to Mondor penile disease (thrombosis of the dorsal vein of the penis) or penile sclerosing lymphangitis. Laboratory evaluation, however, showed a solid lesion, with no vascular component to Doppler ultrasonography and no treponema to immunohistochemistry. Histological and serological tests were compatible with secondary syphilis. Read More
Corymbiform syphilis associated with three other sexually transmitted infections.
An Bras Dermatol 2018 Jan-Feb;93(1):129-132
Dermatology Clinic at Santa Casa de São Paulo - São Paulo (SP), Brazil.
Secondary syphilis can have different clinical presentations, with corymbiform rash as its rarest manifestation. The disease is characterized by a central papule surrounded by smaller ones. We report the case of a man who has sex with man with corymbiform syphilis. Read More
Expanding syphilis testing: a scoping review of syphilis testing interventions among key populations.
- Authors:
- Jason J Ong,
- Hongyun Fu,
- M Kumi Smith,
- Joseph D Tucker
Expert Rev Anti Infect Ther 2018 Apr 23:1-10. Epub 2018 Apr 23.
a Faculty of Infectious and Tropical Diseases , London School of Hygiene and Tropical Medicine , London , United Kingdom.
Introduction: Syphilis is an important sexually transmitted infection (STI). Despite inexpensive and effective treatment, few key populations receive syphilis testing. Innovative strategies are needed to increase syphilis testing among key populations. Read More
Stroke and syphilis: A retrospective study of 53 patients.
- Authors:
- N Ahbeddou,
- K El Alaoui Taoussi,
- A Ibrahimi,
- E H Ait Ben Haddou,
- W Regragui,
- A Benomar,
- M Yahyaoui
Rev Neurol (Paris) 2018 Apr 6. Epub 2018 Apr 6.
Department of Neurology and Neurogenetics "B", Université Mohamed V Souissi, 10010 Rabat, Morocco.
Objective: The aim of this study was to describe the clinical, biological and radiological characteristics of patients with syphilitic vasculitis, and to assess the outcome after treatment.
Methodology: A retrospective review was carried out based on the records of patients with ischemic stroke, and reactive CSF TPHA and VDRL results. None of these patients showed symptoms of any other diseases or had received high doses of penicillin. Read More
Methodology: A retrospective review was carried out based on the records of patients with ischemic stroke, and reactive CSF TPHA and VDRL results. None of these patients showed symptoms of any other diseases or had received high doses of penicillin. Read More
Utility of antitreponemal IgM testing in the diagnosis of early and repeat syphilis among HIV-infected and non-infected patients.
- Authors:
- Maciej Pastuszczak,
- Agnieszka Kotnis-Gąska,
- Bernadetta Jakubowicz,
- Iwona Martyka,
- Monika Bociaga-Jasik,
- Anna Wojas-Pelc
Int J STD AIDS 2018 Jan 1:956462418762849. Epub 2018 Jan 1.
1 Department of Dermatology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.
Until now only non-treponemal tests (e.g. rapid plasma reagin [RPR]) have been used to monitor syphilis activity (e. Read More
Hot News: Sexually Transmitted Infections on the Rise in PrEP Users.
- Authors:
- Pablo Barreiro
AIDS Rev 2018 Jan-Mar;20(1):71
Carlos III-La Paz University Hospital, Madrid, Spain.
Pre-exposure prophylaxis (PrEP) with oral Truvada (tenofovir plus emtricitabine) is effective at preventing HIV infection in high-risk homosexual men. In the United States, PrEP was approved in 2012 and is reimbursed by Medicaid and the majority of private insurers. The situation is diverse and not uniform in the European Union, being PrEP more widely used in France than in the rest of countries. Read More
Health status of Afro-Asian refugees in an Italian urban area: a cross-sectional monocentric study.
- Authors:
- R Del Pinto,
- D Pietropaoli,
- U Russomando,
- P Evangelista,
- C Ferri
Public Health 2018 Apr 5. Epub 2018 Apr 5.
University of L'Aquila, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, 67100, L'Aquila, Italy. Electronic address:
Objectives: The recent sociopolitical events in the Mediterranean and Middle Eastern areas have significantly impacted international migration flows. As disease prevalence and type are different among western and Afro-Asian countries, physicians dealing with refugees should be aware of their specific health needs. We aimed at evaluating the health status and disease history of refugees at their arrival in the urban area of L'Aquila (Italy). Read More
Congenital syphilis.
- Authors:
- Joshua M Cooper,
- Pablo J Sánchez
Semin Perinatol 2018 Apr 4. Epub 2018 Apr 4.
Department of Pediatrics, Divisions of Neonatology and Pediatric Infectious Diseases, Center for Perinatal Research, Nationwide Children's Hospital, The Ohio State University College of Medicine, 700 Children's Drive, RB3, WB5245, Columbus, OH 43205-2664. Electronic address:
Congenital syphilis remains a major public health problem worldwide, and its incidence is increasing in the United States. This review highlights the ongoing problem of this preventable infection, and discusses vertical transmission and clinical manifestations while providing a practical algorithm for the evaluation and management of infants born to mothers with reactive serologic tests for syphilis. Every case of congenital syphilis must be seen as a failure of our public health system to provide optimal prenatal care to pregnant women, as congenital syphilis can be prevented by early and repeated prenatal serologic screening of mothers and penicillin treatment of infected women, their sexual partners, and their newborn infants. Read More
Factors associated with distal symmetric polyneuropathies in adult Zambians: A cross-sectional, observational study of the role of HIV, non-antiretroviral medication exposures, and nutrition.
- Authors:
- Michelle Kvalsund,
- Takondwa Chidumayo,
- Johanna Hamel,
- David Herrmann,
- Douglas Heimburger,
- Amanda Peltier,
- Gretchen Birbeck
J Neurol Sci 2018 May 22;388:61-69. Epub 2018 Feb 22.
Department of Neurology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, USA; Epilepsy Care Team, Chikankata Health Services, Mazabuka, Zambia. Electronic address:
Background: Non-antiretroviral (ART) drug exposures and poor nutrition may be important modifiable risk factors for distal symmetric polyneuropathies (DSP) in sub-Saharan Africa.
Methods: We conducted a cross-sectional study of DSP prevalence and factors associated with DSP among clinic attendees in urban and rural Zambia. All participants underwent neurologist-performed examination. Read More
Methods: We conducted a cross-sectional study of DSP prevalence and factors associated with DSP among clinic attendees in urban and rural Zambia. All participants underwent neurologist-performed examination. Read More
Acceptability and effectiveness of using mobile applications to promote HIV and other STI testing among men who have sex with men in Barcelona, Spain.
- Authors:
- Miguel Alarcón Gutiérrez,
- Manuel Fernández Quevedo,
- Silvia Martín Valle,
- Constanza Jacques-Aviñó,
- Elia Díez David,
- Joan A Caylà,
- Patricia Gracía de Olalla
Sex Transm Infect 2018 Apr 6. Epub 2018 Apr 6.
Servei d'Epidemiologia, Agència de Salut Pública de Barcelona, Barcelona, Spain.
Objective: To evaluate the acceptability and effectiveness of a pilot intervention programme using gay geosocial mobile applications (apps) to offer rapid HIV and other STI tests to men who have sex with men (MSM) in Barcelona between December 2015 and March 2016.
Methodology: We offered rapid HIV, syphilis and hepatitis C testing by sending private messages on apps for sexual and social encounters. Acceptance was defined as the proportion of users who favourably responded to the message and effectiveness was defined as the proportion of users who attended our facilities among those who were interested in attending. Read More
Methodology: We offered rapid HIV, syphilis and hepatitis C testing by sending private messages on apps for sexual and social encounters. Acceptance was defined as the proportion of users who favourably responded to the message and effectiveness was defined as the proportion of users who attended our facilities among those who were interested in attending. Read More
Congenital Syphilis Prevention: Strategies, Evidence, and Future Directions.
- Authors:
- Rosalyn E Plotzker,
- Ryan D Murphy,
- Juliet E Stoltey
Sex Transm Dis 2018 Apr 5. Epub 2018 Apr 5.
California Department of Public Health, Sexually Transmitted Disease Control Branch, Division of Communicable Disease Control, Center for Infectious Diseases.
Background: Congenital syphilis (CS) - the preventable transmission of Treponema pallidum from infected mother to fetus - remains a significant problem worldwide.
Methods: From July through November 2017, 239 articles relevant to CS prevention were identified via keyword searches in PubMed and Google Scholar, ancestry searches, and expert recommendation. Articles were then assessed for 1) measurement of a specified CS or adverse pregnancy outcome (APOs) and 2) geographic setting in high/upper middle income countries according to United Nations criteria. Read More
Methods: From July through November 2017, 239 articles relevant to CS prevention were identified via keyword searches in PubMed and Google Scholar, ancestry searches, and expert recommendation. Articles were then assessed for 1) measurement of a specified CS or adverse pregnancy outcome (APOs) and 2) geographic setting in high/upper middle income countries according to United Nations criteria. Read More
Who should be tested for syphilis? Rationalising syphilis screening in sexual health clinics.
Int J STD AIDS 2018 May;29(6):621
1 Brighton & Sussex Medical School, Brighton, UK.
Non-primary nail-plate syphilis in an HIV-infected patient.
SAGE Open Med Case Rep 2018 28;6:2050313X18767229. Epub 2018 Mar 28.
Infectious Disease Clinic, Department of Medicine, University of Perugia, Perugia, Italy.
A 37-year-old Caucasian male, HIV-infected (CDC A2) in 2012 and on antiretroviral therapy, presented for a follow-up visit. On physical examination, a barely discernible light-colored macular rash was observed on the trunk, not involving the palms and soles. However, clear maculo-papular lesions were present over the proximal volar aspect of both forearms. Read More
A case of secondary syphilis with pulmonary involvement and review of the literature.
Int J STD AIDS 2018 Jan 1:956462418765834. Epub 2018 Jan 1.
1 Division of Infectious Diseases, Faculty of Medicine, Department of Medicine, 65100 Thammasat University , Pathumthani, Thailand.
Syphilis is a sexually transmitted systemic infection caused by Treponema pallidum. We report a case of a heterosexual, HIV-positive man who presented with secondary syphilis and a lung abscess. A bacterial lung abscess was suspected and a computed tomography-guided percutaneous needle aspiration of the lung abscess was performed. Read More
Moulages: Art and History of Medicine.
- Authors:
- Ana L Nocito,
- Hector H Berra
Am J Dermatopathol 2018 Apr 3. Epub 2018 Apr 3.
Health Promotion Department, School of Medicine, National University of Rosario, Argentina.
The aim of this article is to introduce the museum we have at the Pathology Department, School of Medicine of the National University of Rosario, Argentina. The origin dates from to 1922 when Dermatology Professor Dr. Enrique P. Read More
Don't forget about syphilis: the great pretender.
- Authors:
- Nina Vora,
- Patrick French
Br J Hosp Med (Lond) 2018 Apr;79(4):188-189
Consultant in Genitourinary and HIV Medicine, Mortimer Market Centre, London.
CONCOMITANT SEXUALLY TRANSMITTED DISEASES IN PATIENTS WITH DIAGNOSED HIV/AIDS: A RETROSPECTIVE STUDY.
Afr J Infect Dis 2018 7;12(1 Suppl):83-89. Epub 2018 Mar 7.
Department of Internal Medicine, Faculty of Medicine-Institute of Tropical Disease-Universitas Airlangga Hospital, Universitas Airlangga, Surabaya 60286, Indonesia.
Background: Human immunodeficiency virus (HIV) is a virus that causes Acquired Immunodeficiency Syndrome (AIDS) which weaken the human immune system and thus increasing the incidence of sexually transmitted infections (STIs) and vice versa.
Materials And Methods: A retrospective study of STIs in HIV/AIDS patients in (UPIPI) Dr. Soetomo General Hospital Surabaya was conducted from January 1 2013 to December 31 2014. Read More
Materials And Methods: A retrospective study of STIs in HIV/AIDS patients in (UPIPI) Dr. Soetomo General Hospital Surabaya was conducted from January 1 2013 to December 31 2014. Read More
Comparison of Manual and Fully Automated AIX1000 Rapid Plasma Reagin Assays for the Laboratory Diagnosis of Syphilis.
- Authors:
- Alan M Sanfilippo,
- Kristie Freeman,
- John L Schmitz
J Clin Microbiol 2018 Apr 4. Epub 2018 Apr 4.
McLendon Clinical Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina
The analytic performance of the AIX1000, a fully automated and recently FDA cleared rapid plasma reagin (RPR) system, was evaluated by comparison to a manual RPR test in a traditional syphilis testing algorithm. 1,028 consecutive serum samples submitted for syphilis testing to the University of North Carolina Hospitals Clinical Immunology Laboratory were tested per each manufacturer's instructions. 996 samples were nonreactive and 20 were reactive using both the ASI RPR Card System and the AIX1000. Read More
HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study.
- Authors:
- Chris R Kenyon
PLoS One 2018 4;13(4):e0195431. Epub 2018 Apr 4.
HIV/STI Unit, Institute of Tropical Medicine, Antwerp, Belgium.
Background: HIV prevalence varies from 1.7% to 14.8% between ethnic groups in Uganda. Read More
Trends in the relative prevalence of genital ulcer disease pathogens and association with HIV infection in Johannesburg, South Africa, 2007-2015.
- Authors:
- Ranmini S Kularatne,
- Etienne E Muller,
- Dumisile V Maseko,
- Tendesayi Kufa-Chakezha,
- David A Lewis
PLoS One 2018 4;13(4):e0194125. Epub 2018 Apr 4.
Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney, Australia.
Background: In South Africa, treatment of genital ulcer disease (GUD) occurs in the context of syndromic management. GUD aetiological studies have been conducted in Johannesburg since 2007. We report on GUD pathogen prevalence, sero-prevalence of STI co-infections and aetiological trends among GUD patients presenting to a community-based primary healthcare facility in Johannesburg over a 9-year period. Read More
[Prevalence of HIV infection and syphilis and related behaviors in clients in Ya'an of Sichuan province].
Zhonghua Liu Xing Bing Xue Za Zhi 2018 Mar;39(3):329-332
Division of Epidemiology, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
To understand the prevalence of HIV infection and syphilis in clients in Ya'an of Sichuan province. A survey was conducted in clients recruited through snowball method in Ya'an of Sichuan from April 2014 to December 2015. The information of the clients, including basic demography characteristics, AIDS knowledge awareness, high-risk behaviors and others, were collected through face-to-face interviews. Read More
Poisoning histories in the Italian renaissance: The case of Pico Della Mirandola and Angelo Poliziano.
- Authors:
- Gianni Gallello,
- Elisabetta Cilli,
- Fulvio Bartoli,
- Massimo Andretta,
- Lucio Calcagnile,
- Agustin Pastor,
- Miguel de la Guardia,
- Patrizia Serventi,
- Alberto Marino,
- Stefano Benazzi,
- Giorgio Gruppioni
J Forensic Leg Med 2018 Mar 28;56:83-89. Epub 2018 Mar 28.
Department of Cultural Heritage, Alma Mater Studiorum University of Bologna, 1 Ariani Street, 48121 Ravenna, Italy.
Giovanni Pico della Mirandola and Angelo Poliziano were two of the most important humanists of the Italian Renaissance. They died suddenly in 1494 and their deaths have been for centuries a subject of debate. The exhumation of their remains offered the opportunity to study the cause of their death through a multidisciplinary research project. Read More
One-Year Effect of the Medicare Annual Wellness Visit on Detection of Cognitive Impairment: A Cohort Study.
- Authors:
- Nicole R Fowler,
- Noll L Campbell,
- Gerhardt M Pohl,
- Leanne M Munsie,
- Noam Y Kirson,
- Urvi Desai,
- Erich J Trieschman,
- Mark K Meiselbach,
- J Scott Andrews,
- Malaz A Boustani
J Am Geriatr Soc 2018 Apr 2. Epub 2018 Apr 2.
School of Medicine, Indiana University, Indianapolis, IN.
Objectives: To examine the effect of the Medicare Annual Wellness Visit (AWV) on the detection of cognitive impairment and on follow-up cognitive care for older adults.
Design: Retrospective matched-cohort study.
Setting: United States. Read More
Design: Retrospective matched-cohort study.
Setting: United States. Read More
Cardiovascular syphilis: down but not out!
Eur Heart J Cardiovasc Imaging 2018 Mar 28. Epub 2018 Mar 28.
Division of Cardiology, Creighton University, 7500 Mercy Road, Omaha, 68124 NE, USA.
