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    Oral findings in secondary syphilis.
    Med Oral Patol Oral Cir Bucal 2018 Feb 24. Epub 2018 Feb 24.
    Av. Limeira, 901 - Areião Piracicaba - SP, 13414-018 Piracicaba - São Paulo - Brazil
    Background: Syphilis is a sexually transmitted disease caused by Treponema pallidum. However, there are of hematogenic and vertical transmission. All health care professionals must be aware of the manifestations of this condition, such as oral lesions. Read More

    Spectral optical coherence tomography findings in an elderly patient with syphilitic bilateral chronic panuveitis.
    Am J Ophthalmol Case Rep 2018 Mar 8;9:56-61. Epub 2018 Jan 8.
    Department of Ophthalmology, Hospital Universitario Austral, Argentina.
    Purpose: To report the spectral domain optical coherence tomography (SD-OCT) features of a focal retinitis in an elderly male patient with bilateral syphilitic panuveitis.

    Observations: In the left eye (LE), spectral domain SD-OCT images during the active period revealed hyperreflectivity extending through the full thickness of the retina with no individualization of the layers, except for the retinal pigment epithelium. Once the lesion healed, SD-OCT imaging revealed an inner retinal atrophy and a mild disruption of the retinal pigment epithelium. Read More

    Rapid diagnostic test for antenatal syphilis screening in low-income and middle-income countries: a systematic review and meta-analysis.
    BMJ Open 2018 Feb 21;8(2):e018132. Epub 2018 Feb 21.
    School of Health and Related Research, University of Sheffield, Sheffield, UK.
    Objectives: To undertake a systematic review and meta-analysis to evaluate the test performance including sensitivity and specificity of rapid immunochromatographic syphilis (ICS) point-of-care (POC) tests at antenatal clinics compared with reference standard tests (non-treponemal (TP) and TP tests) for active syphilis in pregnant women.

    Methods: Five electronic databases were searched (PubMed, EMBASE, CRD, Cochrane Library and LILACS) to March 2016 for diagnostic accuracy studies of ICS test and standard reference tests for syphilis in pregnant women. Methodological quality was assessed using QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies). Read More

    Enhanced Molecular Typing of Treponema pallidum subsp. pallidum strains from four Italian hospitals shows geographical differences in strain type heterogeneity, widespread resistance to macrolides, and lack of mutations associated with doxycycline resistance.
    Sex Transm Dis 2017 Oct 10. Epub 2017 Oct 10.
    Health Sciences Department, Section of Dermatology, San Martino University Hospital, Genoa, Italy.
    Background: Although syphilis rates have been relatively high in Italy for over 15 years, no data on the molecular types of Treponema pallidum subsp. pallidum (T. pallidum) circulating in this country are yet available. Read More

    Conceptualizing Geosexual Archetypes: Mapping the sexual travels and ego-centric sexual networks of gay and bisexual men in Toronto, Canada.
    Sex Transm Dis 2017 Oct 25. Epub 2017 Oct 25.
    Background: There are complex, synergistic and persistent sexually transmitted infection (STI) epidemics affecting gay, bisexual and other men who have sex with men (gbMSM) in every major urban centre across North America. We explored the spatial architecture of egocentric sexual networks for gbMSM in Toronto, Canada.

    Methods: Our integrative mixed methods study included in-depth interviews with 31 gbMSM between May and July 2016. Read More

    Missed opportunities for HIV and syphilis testing among men who have sex with men in China: a cross-sectional study.
    Sex Transm Dis 2017 Dec 5. Epub 2017 Dec 5.
    Social Entrepreneurship for Sexual Health (SESH) Global, Guangdong, China.
    Background: Men who have sex with men(MSM) are at high risk of HIV/syphilis. To inform strategies for dual testing, we describe patterns of HIV/syphilis testing, and examine factors associated with never testing for HIV/syphilis in China.

    Methods: An online survey(2016) was completed by MSM from eight cities: men born biologically male, age >16 years, and had sex with another man at least once during their lifetime. Read More

    Characteristics Associated with Delivery of an Infant with Congenital Syphilis and Missed Opportunities for Prevention - California, 2012-2014.
    Sex Transm Dis 2018 Jan 4. Epub 2018 Jan 4.
    Background: Congenital syphilis (CS), the transmission of Treponema pallidum from mother to fetus during pregnancy, can cause adverse birth outcomes. During 2012-2014, the CS rate in California increased >200% from 6.6 to 20. Read More

    A network analysis of sexually transmitted diseases and online hookup sites among men who have sex with men.
    Sex Transm Dis 2018 Jan 4. Epub 2018 Jan 4.
    Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence RI.
    Background: Sexually transmitted diseases (STDs) are increasing among gay, bisexual, and other men who have sex with men (MSM). Little is known about the use of websites and mobile phone applications to meet sexual partners ("hookup sites") and association with STD diagnoses.

    Methods: We performed a demographic and behavioral assessment of 415 MSM presenting to the Rhode Island STD clinic. Read More

    Social Vulnerability in Congenital Syphilis Case Mothers: Qualitative Assessment of Cases in Indiana, 2014-2016.
    Sex Transm Dis 2018 Jan 4. Epub 2018 Jan 4.
    Centers for Disease Control and Prevention, NCHHSTP/DSTDP, Field Services Branch and Indiana State Department of Health, STD Program Centers for Disease Control and Prevention, NCHHSTP/DSTDP, Social and Behavioral Research and Evaluation Branch Indiana State Department of Health, STD Program and Epidemiology Resource Center.
    Background: Congenital syphilis occurs when a pregnant woman with syphilis is not diagnosed or treated and the infection is passed in utero, causing severe infant morbidity and mortality. Congenital syphilis is easily prevented if women receive timely and adequate prenatal care. Cases of congenital syphilis are considered indicators of problems in the safety net. Read More

    Pathways to congenital syphilis prevention: A rapid qualitative assessment of barriers, and the public health response, in Caddo Parish, Louisiana.
    Sex Transm Dis 2018 Jan 10. Epub 2018 Jan 10.
    Centers for Disease Control and Prevention, Division of STD Prevention, 1600 Clifton Road, MS E-44, Atlanta, GA 30333, 404-639-4488, 404-639-8622 (fax). University of Maryland, Department of Anthropology, University of Maryland, 1111 Woods Hall, 4302 Chapel Lane, College Park, MD 20742, 301-405-1437. Centers for Disease Control and Prevention, Division of STD Prevention, 1600 Clifton Road, MS E-44, Atlanta, GA 30333, 404-639-4488. Population Health Manager, Thomas Jefferson Health District, Virginia Department of Health, 434-972-6232, Director, Bureau of Infectious Diseases, Louisiana Office of Public Health, 1450 Poydras St., Suite 2136, New Orleans, LA 70112. 504-568-7474 (main office).
    Background: Congenital syphilis (CS) disproportionately affects racial and ethnic minority women, especially in the US South. While CS is relatively easy and inexpensive to prevent through screening and treatment of pregnant women, CS cases have continued to rise and are concentrated in relatively few US counties and states. In 2010, Louisiana had the highest case rate in the country for primary, secondary, and congenital syphilis, with the highest number of CS cases in northwest Louisiana, where Shreveport is located. Read More

    HIV Co-infection among Persons Diagnosed with Sexually Transmitted Diseases, San Francisco, 2007-2014.
    Sex Transm Dis 2018 Jan 16. Epub 2018 Jan 16.
    San Francisco Department of Public Health, San Francisco, California, USA.
    Background: Early syphilis, gonorrhea, and chlamydia but not HIV infections have increased in San Francisco, primarily among men.

    Methods: We linked records of persons reported with early syphilis, gonorrhea, and chlamydia to records of persons reported with HIV to measure the proportion and characteristics of San Francisco residents with HIV-STD co-infection between 2007 and 2014. We measured trends in HIV co-infection separately for men and women for each STD. Read More

    The epidemiology of syphilis in New York City; historic trends and the current outbreak among men who have sex with men, 2016.
    Sex Transm Dis 2018 Jan 19. Epub 2018 Jan 19.
    Division of STD Prevention, National Center for HIV, Hepatitis, STD, and TB Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, 30333.
    Background: Male primary and secondary (P&S) and early latent (EL) syphilis cases have increased markedly in New York City (NYC) after a historic nadir in 1998. The majority of cases are among men-who-have-sex-with-men (MSM). We describe the epidemiology of syphilis among NYC males to provide a model of how one jurisdiction collects, analyzes, interprets, uses, and disseminates local data to guide programmatic activities directed at syphilis control. Read More

    STI positivity rate and treatment uptake among female and male sexual assault victims attending the Amsterdam STI clinic between 2005 and 2016.
    Sex Transm Dis 2018 Feb 1. Epub 2018 Feb 1.
    Department of Infectious Diseases, Public Health Service of Amsterdam (GGD Amsterdam), Amsterdam, the Netherlands.
    Background: Victims could become infected with sexually transmitted infections (STI) during a sexual assault. Several guidelines recommend presumptive antimicrobial therapy for sexual assault victims (SAV). We assessed the STI positivity rate and treatment uptake of female and male SAV at the Amsterdam STI clinic. Read More

    New Human Immunodeficiency Virus diagnoses among Men Who Have Sex with Men attending STD clinics, STD Surveillance Network, January 2010 to June 2013.
    Sex Transm Dis 2018 Feb 7. Epub 2018 Feb 7.
    Centers for Disease Control and Prevention, Surveillance and Data Management Branch, Division of STD Prevention (NCCHSTP).
    Objective: To estimate new HIV diagnosis rates among HIV negative MSM who are repeatedly tested for HIV in sexually transmitted disease (STD) clinics, and assess the impact of demographic and disease-specific characteristics that are associated with higher HIV diagnosis rates.

    Study Design: Retrospective analysis using 2010-2013 data from the STD Surveillance Network (SSuN), a sentinel surveillance system comprised of health departments in 12 cities conducting sentinel surveillance in 40 STD clinics. We analyzed data from all MSM repeatedly (≥2 times) tested for HIV, with an initial negative HIV test required for staggered cohort entry. Read More

    Relative Impact of Different Strategies for Allocating Federal Funds for Syphilis Prevention.
    Sex Transm Dis 2018 Feb 13. Epub 2018 Feb 13.
    Both authors are with the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
    Background: Improvements in resource allocation can increase the benefits of federally-funded sexually transmitted disease (STD) prevention activities. The purpose of this study was to illustrate how different strategies for allocating federal funds to sub-national districts for syphilis prevention might affect the incidence of syphilis at the national level.

    Methods: We modeled syphilis rates by district and year using an equation based on a previous analysis of state-level syphilis elimination funding and syphilis case rates from 1998 to 2005 in the United States. Read More

    Context appropriate interventions to prevent syphilis: a narrative review.
    Sex Transm Dis 2018 Feb 13. Epub 2018 Feb 13.
    Division of STD Prevention, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta GA.
    Background: The success of an intervention to prevent syphilis will depend on the context and the goal of the intervention. To help programs choose interventions, we reviewed major changes in context and types of interventions that may be effective.

    Methods: We reviewed the literature on the changing context of syphilis in the United States and interventions to prevent syphilis, focusing on papers that included evidence of effectiveness. Read More

    Multi-state Syphilis Outbreak among American Indians, 2013-2015.
    Sex Transm Dis 2018 Feb 13. Epub 2018 Feb 13.
    Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
    This article summarizes a multi-state outbreak of heterosexual syphilis, including 134 cases of syphilis in adults and adolescents and at least two cases of congenital syphilis, which occurred on an American Indian reservation in the United States during 2013-2015. In addition to providing salient details about the outbreak, the article seeks to document the case-finding and treatment activities undertaken, their relative success or failure, and the lessons learned from a coordinated, multiagency response. Of 134 adult cases of syphilis, 40% were identified by enhanced, interagency contact tracing and partner services; 26% through symptomatic testing; and 16% through screening of asymptomatic individuals as the result of an electronic medical record (EMR) screening prompt. Read More

    Reported Primary and Secondary Syphilis Cases in the United States: Implications for HIV Infection.
    Sex Transm Dis 2018 Feb 15. Epub 2018 Feb 15.
    Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
    Background: Recent increases in syphilis among men who have sex with men (MSM) are especially concerning, given the biologic and epidemiologic associations between syphilis and HIV infection. We sought to better describe the current epidemiology of primary and secondary (P&S) syphilis and the prevalence of HIV infection among reported P&S syphilis cases by demographic group, including sex of sex partner, in the United States in 2016.

    Methods: We reviewed national P&S syphilis case report data from 2016, including available risk factor information such as sex of sex partner and HIV status. Read More

    Secondary pulmonary syphilis: Case report and review of literature.
    Ann Dermatol Venereol 2018 Feb 17. Epub 2018 Feb 17.
    Service de dermatologie, hôpital Emile-Muller, GHR Mulhouse-Sud Alsace, 20, avenue du Dr-René-Laennec, 68100 Mulhouse, France.
    Introduction: Syphilis is a sexually transmitted disease that can affect numerous organs in its secondary or tertiary stages. We describe a case of secondary syphilis with pulmonary involvement and we present a literature review.

    Patients And Methods: A 69-year-old male patient was admitted to hospital for dyspnoea and extended papular exanthema with palmoplantar involvement. Read More

    Lakartidningen 2018 Feb 15;115. Epub 2018 Feb 15.
    Karolinska universitetslaboratoriet - Klinisk Patologi Cytologi Stockholm, Sweden Karolinska universitetslaboratoriet - Klinisk Patologi och Cytologi Stockholm, Sweden.
    Syphilis - an old imitator is back on the stage Syphilis is one of the oldest sexually transmitted infections and caused by the spirochete Treponema pallidum. The incubation time is 10-90 days and patients are contagious for approximately one year. In Sweden all blood donors and pregnant women are screened. Read More

    Prevalence of asymptomatic sexually transmitted infections in HIV-positive men who have sex with men in Germany: results of a multicentre cross-sectional study.
    Infection 2018 Feb 19. Epub 2018 Feb 19.
    Research and Clinical Care Center, Medizinisches Versorgungszentrum Karlsplatz, Karlsplatz 8, 80335, Munich, Germany.
    Purpose: Sexually transmitted infections (STIs) occur frequently in risk populations. Hereby, the role of screening-programmes remains controversial. Our study aimed to determine the prevalence of STI infections in HIV-positive men-who-have-sex-with-men (MSM). Read More

    Rollout of rapid point of care tests for antenatal syphilis screening in Ghana: healthcare provider perspectives and experiences.
    BMC Health Serv Res 2018 Feb 20;18(1):130. Epub 2018 Feb 20.
    London School of Hygiene and Tropical Medicine, London, UK.
    Background: Effective implementation of rapid point of care tests (POCTs) for antenatal syphilis screening especially in settings where antenatal care attendance is high, can significantly increase screening coverage and treatment uptake. The operational challenges of introducing rapid syphilis POCTs at scale needs to be investigated. This study explores healthcare providers' experiences and challenges in antenatal syphilis screening following the national rollout of rapid syphilis POCTs in Ghana. Read More

    Bejel in Cuba: molecular identification of Treponema pallidum subsp. endemicum in patients diagnosed with venereal syphilis.
    Clin Microbiol Infect 2018 Feb 15. Epub 2018 Feb 15.
    Department of Biology, Masaryk University, Brno, 625 00, Czech Republic. Electronic address:
    Objectives: Bejel, caused by Treponema pallidum subsp. endemicum (TEN), was until now considered as a non-venereal disease endemic in areas with hot and dry climates. This study has identified TEN in clinical samples from Cuban patients previously diagnosed with syphilis. Read More

    Sexually transmitted infections and immune activation among HIV-infected but virally suppressed youth on antiretroviral therapy.
    J Clin Virol 2018 Feb 7;102:7-11. Epub 2018 Feb 7.
    Duke University, School of Medicine, Department of Pediatrics, 133 MSRB I, DUMC Box 2644, Durham, NC, 27710, United States.
    Background: Human immunodeficiency virus (HIV) infection is associated with chronic immune activation, and concurrent sexually transmitted infections (STIs) may increase immune activation.

    Objectives: Because HIV-infected youth are at high risk of STIs and little is known about the impact of STIs on immune activation in HIV-infected youth, we conducted an exploratory study examining the association between STIs and systemic inflammation and immune activation among HIV-infected adolescents.

    Study Design: Forty-nine behaviorally infected U. Read More

    Evaluation of a recombinant multiepitope antigen for diagnosis of hepatitis C virus: A lower cost alternative for antigen production.
    J Clin Lab Anal 2018 Feb 17. Epub 2018 Feb 17.
    Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
    Background: The most of the hepatitis C-infected patients remain undiagnosed until they develop severe liver damage or submitted for serological screening.

    Objective: To evaluate a recombinant multiepitope protein for detection of IgG anti-hepatitis C virus.

    Method: A synthetic gene was cloned, expressed in Escherichia coli, and the recombinant protein was purified. Read More

    Sexual Behavior With Noncommercial Partners: A Concurrent Partnership Study Among Middle-Aged Female Sex Workers in China.
    J Sex Res 2018 Feb 16:1-11. Epub 2018 Feb 16.
    a Department of Epidemiology and Biostatistics, School of Public Health , University of Maryland , College Park.
    Female sex workers (FSWs) often engage in concurrent partnerships, meaning they have multiple sexual relationships at the same time. The objective of this study was to investigate sexual concurrency and its associations with condom use and syphilitic infections among FSWs over age 35. Respondent-driven sampling was used to recruit 1,245 FSWs in Nanning, Hefei, and Qingdao, China. Read More

    Factors associated with HIV co-infection in cases of acquired syphilis reported in a Reference Center for Sexually Transmitted Diseases and AIDS in the municipality of São Paulo, Brazil, 2014.
    Epidemiol Serv Saude 2018 15;27(1):e20171678. Epub 2018 Feb 15.
    Escola de Enfermagem, Universidade de São Paulo, São Paulo, SP, Brazil.
    Objective: to describe sociodemographic and behavioral characteristics and to identify factors associated with human immunodeficiency virus (HIV) co-infection in cases of acquired syphilis reported in a Reference Center for Sexually Transmitted Diseases (STD) and AIDS.

    Methods: cross-sectional study with secondary data from a Reference Center for STD and AIDS in the municipality of São Paulo, Brazil, in 2014; the Poisson regression was used to estimate prevalence ratios (PR) and 95% confidence intervals (95%CI).

    Results: 648 cases of acquired syphilis were reported, and 98% were male; 88% were men who have sex with men (MSM) and 57% had HIV co-infection; male sex (PR=1. Read More


    Retrospective review ofPCR and serology results: Are both tests necessary?
    J Clin Microbiol 2018 Feb 14. Epub 2018 Feb 14.
    Department of Microbiology, Pathology Queensland, Townsville, Australia.
    There has been a resurgence of syphilis diagnoses in Australia. We investigated whether ourpolymerase chain reaction (PCR) test provides any additional diagnostic information over syphilis serology (chemi-luminescence immunoassay (CMIA),particle agglutination (TPPA) and rapid reagin (RPR) flocculation test). A retrospective audit was conducted of allPCR requests that came through our laboratory from January 2010 to June 2017; data collected included age, gender, site of swab,PCR, syphilis serology and HSV 1 and HSV 2 PCR results. Read More

    Heritage of Stanisław Ostrowski - the only one medical doctor who became state Polish President - Patriae Semper Fidelis.
    Clujul Med 2018 15;91(1):129-142. Epub 2018 Jan 15.
    Pawiak Prison Historical Museum in Warsaw, Director Emeritus of the Pawiak Prison Historical Museum in Warsaw, Poland.
    Aim: Our purpose was to write a biography of Stanisław Ostrowski that would address in the first place the medical aspect of his professional life, with a comprehensive approach of others fields of his activity.

    Methods: We essentially grounded the paper on primary resources that were papers authored by Ostrowski including his scientific publications, memories, speeches as well as contemporaneous official documents that referred to Ostrowski. Second resources were also used to double check some data from primary resources and to place the biography of Stanisław Ostrowski in a proper background with special care to social, professional and political context. Read More

    Intimate Partner Violence Correlates With A Higher HIV Incidence Among MSM: A 12-Month Prospective Cohort Study in Shenyang, China.
    Sci Rep 2018 Feb 13;8(1):2879. Epub 2018 Feb 13.
    Key Laboratory of AIDS Immunology of the National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, No. 155, Nanjingbei Street, Heping District, Shenyang, Liaoning Province, 110001, China.
    Intimate partner violence (IPV) and HIV are highly prevalent worldwide among MSM. However, the association between IPV and HIV seroconversion is virtually unknown. This 12-month prospective cohort study was conducted among MSM in Shenyang, China to explore the causality between IPV and the incidence of HIV. Read More

    Social networks as drivers of syphilis and HIV infection among young men who have sex with men.
    Sex Transm Infect 2018 Feb 9. Epub 2018 Feb 9.
    Departments of Medicine and Public Health Sciences, University of Chicago, Chicago, IL, USA.
    Objectives: Syphilis and HIV epidemics overlap, yet little is known about combined network and behavioural factors that drive syphilis-HIV coinfection. Our study objective was to assess network contexts and sexual behaviours associated with syphilis-HIV co-infection and monoinfection among a particularly vulnerable subgroup: young Black men who have sex with men (YBMSM). To achieve this objective, we examined factors associated with coinfection by each subgroup as classified by syphilis-HIV infection status: (A) HIV monoinfected, (B) syphilis monoinfected and (C) neither syphilis infected nor HIV infected. Read More

    Comparing the characteristics of users of an online service for STI self-sampling with clinic service users: a cross-sectional analysis.
    Sex Transm Infect 2018 Feb 7. Epub 2018 Feb 7.
    School of Population Health and Environmental Sciences, Centre for Global Health and Health Partnerships, King's College London, London, UK.
    Objectives: Online services for self-sampling at home could improve access to STI testing; however, little is known about those using this new modality of care. This study describes the characteristics of users of online services and compares them with users of clinic services.

    Methods: We conducted a cross-sectional analysis of routinely collected data on STI testing activity from online and clinic sexual health services in Lambeth and Southwark between 1January 2016 and 31March 2016. Read More

    High Burden of Human Papillomavirus Infection in Madagascar: Comparison With Other Sexually Transmitted Infections.
    Infect Dis (Auckl) 2018 1;11:1178633717752686. Epub 2018 Feb 1.
    Division of Gynaecology, Department of Gynaecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.
    Background: In Madagascar, human papillomavirus (HPV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV) infection, as well as syphilis share common risk factors but seem to differ in their prevalence. We measured and compared their prevalence in the country.

    Methods: The data used in this study came from the Saint Damien Health Centre in Ambanja, Madagascar. Read More

    Antiretroviral therapy suppresses rectal HIV-RNA shedding despite inflammation in MSM with rectalandinfections-a cross-sectional, single-center study.
    Sex Transm Infect 2018 Feb 3. Epub 2018 Feb 3.
    Department of Dermatology, University Hospital, University of Duisburg-Essen, Essen, Germany.
    Objectives: Rectal infections withand/or(CT/NG) are common in men who have sex with men (MSM) and are linked to HIV transmission. However, rectal CT/NG infections are often asymptomatic and it is not known how they contribute to HIV transmission. We assessed clinical and cytological signs of inflammation as well as rectal HIV-RNA in HIV-infected MSM with and without CT/NG infection. Read More

    Impact of insurance coverage on HIV transmission potential among antiretroviral therapy-treated youth living with HIV.
    AIDS 2018 Feb 8. Epub 2018 Feb 8.
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania.
    Objective: To identify the prevalence of high HIV transmission potential in a cohort of youth living with HIV (YLWH), and determine the impact of insurance coverage on potential for HIV transmission.

    Design: Retrospective cohort study of antiretroviral therapy (ART)-treated YLWH at a US adolescent HIV clinic, 2002-2015.

    Methods: The primary exposure was presence or absence of insurance, defined as private, public or pharmacy-only coverage. Read More

    Antenatal care service quality increases the odds of utilizing institutional delivery in Bahir Dar city administration, North Western Ethiopia: A prospective follow up study.
    PLoS One 2018 8;13(2):e0192428. Epub 2018 Feb 8.
    School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
    Background: In Ethiopia, more than 62% of pregnant women attend antenatal care at least once, yet only about one in four women give birth at health facility. This gap has fueled the need to investigate on the quality of ANC services at public health facilities and its link with the use of institutional delivery.

    Objective: To assess the linkage between ANC quality and the use of institutional delivery among pregnant women attending ANC at public health facilities of BDR City Administration. Read More

    How Good Is Your Rule of Thumb? Validating Male-to-Female Case Ratio as a Proxy for Men Who Have Sex With Men Involvement in N. gonorrhoeae Incidence at the County Level.
    Sex Transm Dis 2018 Mar;45(3):212-215
    Background: Lacking information on men who have sex with men (MSM) for most reported cases, sexually transmitted disease (STD) programs in the United States have used crude measures such as male-to-female case ratios (MFCR) as a rule of thumb to gauge MSM involvement at the local level, primarily with respect to syphilis cases in the past. Suitability of this measure for gonorrhea incidence has not previously been investigated.

    Methods: A random sample of gonorrhea cases reported from January 2010 through June 2013 were interviewed in selected counties participating in the STD Surveillance Network to obtain gender of sex partners and history of transactional sex. Read More

    Rising Chlamydia and Gonorrhoea Incidence and Associated Risk Factors Among Female Sex Workers in Australia: A Retrospective Cohort Study.
    Sex Transm Dis 2018 Mar;45(3):199-206
    Background: Female sex workers in Australia have achieved some of the lowest documented prevalences of human immunodeficiency virus (HIV) and other sexually transmissible infections globally but rates overall are increasing in Australia and warrant closer investigation.

    Methods: We constructed a retrospective cohort using repeat testing data extracted from a network of 42 sexual health clinics. Poisson and Cox regression were used to determined trends in incidence and risk factors for HIV, chlamydia, gonorrhoea, and infectious syphilis among female sex workers. Read More

    Factors Associated With Syphilis Testing and a History of Syphilis Infection Among a Sample of Transgender Women in Jamaica.
    Sex Transm Dis 2018 Mar;45(3):158-162
    Background: Globally, social inequalities contribute to elevated sexually transmitted infections (STIs) rates among transgender women. High syphilis prevalence has been documented among transgender women in Latin America. Little is known, however, of syphilis testing uptake among transgender women in Jamaica, where homosexuality is criminalized. Read More

    Differences in Partner Services Outcomes for Men Who Have Sex With Men Diagnosed With Primary and Secondary Syphilis by HIV Serostatus.
    Sex Transm Dis 2018 Mar;45(3):152-157
    Background: Differences in partner services outcomes in men who have sex with men (MSM) by HIV serostatus have not been explored as a potential driver of differential early syphilis (ES) burden in this population.

    Methods: We compared partner services outcomes (number of partners named, notified, tested, diagnosed, and treated) between HIV-positive and HIV-negative MSM initiated for ES partner services in Texas from 2013 to 2016 using logistic regression and Wilcoxon-Mann-Whitney tests. Logistic regression was used to assess the relationship between HIV serostatus and having a no-partner-initiated (NPI) partner services interview controlling for demographic characteristics, prior partner services interactions, and geosocial phone application use. Read More

    Neurosyphilis: Knowledge Gaps and Controversies.
    Sex Transm Dis 2018 Mar;45(3):147-151
    From the Johns Hopkins University School of Medicine, Baltimore, MD.
    After reaching a nadir at the turn of the century, syphilis rates in the United States have increased since 2000. Treponema pallidum may disseminate to the central nervous system within hours to days after inoculation. In this review, we focus on knowledge gaps and areas of controversy in neurosyphilis epidemiology, diagnosis, and management. Read More

    Rapid Increase in Reports of Syphilis Associated With Men Who Have Sex With Women and Women Who Have Sex With Men, Japan, 2012 to 2016.
    Sex Transm Dis 2018 Mar;45(3):139-143
    Background: In Japan, syphilis reports have recently increased rapidly. However, unlike other developed countries where men who have sex with men (MSM) were associated with the rise, the increase in Japan has been attributed more to men who have sex with women (MSW) and women who have sex with men (WSM). We report on this increase based on surveillance data. Read More

    HIV and syphilis epidemic among MSM and non-MSM aged 50 and above in Shanghai, China: A yearly cross-sectional study, 2008-2014.
    Glob Public Health 2018 Feb 8:1-9. Epub 2018 Feb 8.
    a Department of Epidemiology , Fudan University School of Public Health , Shanghai , People's Republic of China.
    The magnitude of the HIV and syphilis epidemic among Chinese men ages 50 and older is unclear. In this study, we aimed to characterise and compare the prevalence of HIV and syphilis infections; linkage to care among those infected with HIV; and the geographic distribution of the two epidemics among elderly men who have sex with men (MSM) and non-MSM in Shanghai, China. This cross-sectional study involved 12,910 men ages 50 and above who participated in the HIV voluntary and counselling testing programme each year from 2008 to 2014. Read More

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