35,774 results match your criteria Syphilis


Paroxysmal Cold Hemoglobinuria in an Adult with Respiratory Syncytial Virus.

Case Rep Hematol 2018 13;2018:7586719. Epub 2018 Nov 13.

Division of Hematology and Medical Oncology, Department of Medicine, Mount Sinai Beth Israel, Mount Sinai Hospital, New York, NY, USA.

Paroxysmal cold hemoglobinuria (PCH) is a rare form of cold autoimmune hemolytic anemia first discovered in the early 20th century in adults with tertiary syphilis. Today, it is more commonly seen in children as a life-threatening anemia during a viral upper respiratory tract infection (URI). Although respiratory syncytial virus (RSV) has previously been reported to cause PCH in a child, herein we present the first documented case in an adult. Read More

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November 2018

Early neurosyphilis presenting with multiple cranial nerve palsies: A case report of management by combined penicillin-corticosteroid treatment.

J Infect Chemother 2018 Dec 8. Epub 2018 Dec 8.

Division of Neurology, Sendai City Hospital, 1-1-1 Asutonagamachi, Taihaku-ku, Sendai 982-8502, Miyagi, Japan.

Early neurosyphilis commonly appears in basilar meninges, and its meningeal inflammation can spread to neighboring cranial nerves, resulting in some cranial nerve palsies. Herein, we report a case of a 51-year-old man who presented with right peripheral facial nerve palsy. His symptoms completely disappeared with prednisolone monotherapy without antibiotics use and were not exacerbated during clinical treatment. Read More

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December 2018

Bilateral coronary ostial stenosis and aortic regurgitation in a patient with cardiovascular syphilis.

J Cardiol Cases 2012 Dec 15;6(6):e173-e175. Epub 2012 Sep 15.

Department of Cardiovascular Surgery, Tokyo Medical University Hospital, 6-7-1 Nishshinjuku, Shinjyuku-ku, Tokyo 160-0023, Japan.

Cardiovascular syphilis is associated with the tertiary stage of syphilis infection; it involves the ascending aorta and can cause aortic aneurysm, aortic regurgitation, and coronary ostial stenosis. We report a surgical case of bilateral coronary ostial lesion and aortic regurgitation due to syphilitic aortitis. < Syphilitic aortitis involves the ascending aorta, resulting in aortic aneurysm, aortic regurgitation, and coronary ostial stenosis. Read More

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December 2012

[Syphilis epidemiological report. Chile, 2016].

Rev Chilena Infectol 2018 ;35(3):284-296

División de Planificación Sanitaria, Ministerio de Salud de Chile, Chile.

Syphilis is produced by Treponema pallidum, which is acquired mainly through sexual contact and transplacental, but can also be acquired by transfusion of contaminated human blood and direct accidental inoculation. The natural history of the infection is characterized by three symptomatic clinical stages: primary, secondary and tertiary syphilis; these last two are preceded by asymptomatic or latent stages of the disease: early latent syphilis and late latent syphilis. This report presents the epidemiological situation of syphilis in Chile up to 2016, using as a method the descriptive analysis of cases that entered surveillance. Read More

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January 2018

Syphilis among Female Sex Workers: Results of Point-of-Care Screening during a Cross-Sectional Behavioral Survey in Burkina Faso, West Africa.

Int J Microbiol 2018 8;2018:4790560. Epub 2018 Nov 8.

Institut de Recherche en Sciences de la Santé (IRSS/CNRST), Ouagadougou, Burkina Faso.

Background: Syphilis among female sex workers (FSW) remains a public health concern due to its potential impact on their health and the possibility of transmission to their clients, partners, and children. Recent data on the prevalence of syphilis in the population in West Africa are scarce. The objective of this study was to measure the seroprevalence of syphilis serological markers among female sex workers in Burkina Faso. Read More

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November 2018

National Trends and Reported Risk Factors Among Pregnant Women With Syphilis in the United States, 2012-2016.

Obstet Gynecol 2018 Dec 4. Epub 2018 Dec 4.

CDC Foundation and the Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.

Objective: To describe recent syphilis trends among pregnant women and to evaluate the prevalence of reported high-risk behaviors in this population.

Methods: We analyzed U.S. Read More

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December 2018

Needle lost in the haystack: multiple reaction monitoring fails to detect candidate protein biomarkers in plasma and urine samples from individuals with syphilis.

F1000Res 2018 19;7:336. Epub 2018 Mar 19.

HIV/STI Unit, Institute of Tropical Medicine, Antwerp, 2000, Belgium.

Current syphilis diagnostic strategies are lacking a sensitive manner of directly detecting antigens. A diagnostic test that could directly detect antigens in individuals with syphilis would be of considerable clinical utility, especially for the diagnosis of reinfections and for post-treatment serological follow-up. In this study, 11 candidate biomarker proteins were chosen according to their physiochemical characteristics, specificity and predicted abundance. Read More

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March 2018
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Identifying missed clinical opportunities for the earlier diagnosis of HIV in Australia, a retrospective cohort data linkage study.

PLoS One 2018 6;13(12):e0208323. Epub 2018 Dec 6.

Infectious Diseases, Prince of Wales Hospital, Sydney, NSW, Australia.

Background: Treatment as prevention approaches for HIV require optimal HIV testing strategies to reduce undiagnosed HIV infections. In most settings, HIV testing strategies still result in unacceptably high rates of missed and late diagnoses. This study aimed to identify clinical opportunities for targeted HIV testing in persons at risk to facilitate earlier HIV diagnosis in New South Wales, Australia; and to assess the duration between the diagnosis of specific conditions and HIV diagnosis. Read More

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December 2018

Prevalence of Human Papillomavirus, HIV and other sexually transmitted infections among men having sex with men in Togo: a national cross-sectional survey.

Clin Infect Dis 2018 Dec 6. Epub 2018 Dec 6.

Université de Lomé, Faculté des Sciences de la Santé, Département de Santé Publique, Lomé, Togo.

Background: Sub-Saharan Africa is a region of both high HIV and anal cancer incidence. We conducted the first national study in Togo to assess HPV, HIV and other Sexually Transmitted Infections (STIs) prevalence among Men having Sex with Men (MSM).

Methods: A multicentric cross-sectional study was conducted among MSM recruited in four Togolese cities based on the respondent-driven sampling method. Read More

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December 2018

Optimization strategies for HIV, hepatitis and syphilis testing in Infectious Disease Clinic and Dermatology Unit of Modena: seven-years results of collaboration experience.

J Eur Acad Dermatol Venereol 2018 Dec 6. Epub 2018 Dec 6.

Clinic of Infectious Diseases, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.

Background: Screening tests for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis infections performed in at-risk population show a higher number of positive tests compared to those carried out in the general population. "Test & Counselling" Ambulatory of Infectious Disease Clinic (T&C-IDC) and Sexually Transmitted Diseases Ambulatory of Dermatology Unit (STDs-DU) of Modena began collaboration in 2010 and adopted a common diagnostic serological profile since 2013.

Objectives: The main objective was to analyse the number of screening tests performed in the T&C-IDC and STDs-DU, comparing the results obtained after the adoption of the shared protocol with the previous period. Read More

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December 2018

Contraceptive use and the risk of sexually transmitted infection: systematic review and current perspectives.

Open Access J Contracept 2018 12;9:91-112. Epub 2018 Nov 12.

Global Health, Population and Nutrition, FHI 360, Durham, NC, USA,

Purpose: Evidence on the association between contraceptive use and risk of sexually transmitted infections (STIs) and bacterial vaginosis (BV) is lacking, with few prospective studies. We systematically reviewed the last 10 years' evidence on the association between contraception and STI/BV, building on the most recent systematic reviews published in 2006 and 2009.

Methods: We searched the MEDLINE and POPLINE databases for peer-reviewed articles p ublished between January 1, 2008 and January 31, 2018 reporting prospective studies that assessed the association between contraceptive use and incident STI and/or incident or recurrent BV. Read More

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November 2018

Congenital syphilis and other STIs rise in the USA.

Authors:
Roxanne Nelson

Lancet Infect Dis 2018 Nov 24;18(11):1186-1187. Epub 2018 Oct 24.

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November 2018

Venue-Based HIV-Testing: An Effective Screening Strategy for High-Risk Populations in Lima, Peru.

AIDS Behav 2018 Nov 30. Epub 2018 Nov 30.

Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA.

Venue-based testing may improve screening efforts for HIV and syphilis, thereby reducing transmission. We offered onsite rapid dual HIV and syphilis testing at venues popular among MSM and/or transgender women in Lima, Peru. We used Poisson regression to calculate adjusted prevalence ratios (aPRs) for factors associated with each infection. Read More

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November 2018

Syphilis as an atypical cause of perianal fissure.

J Surg Case Rep 2018 Nov 27;2018(11):rjy320. Epub 2018 Nov 27.

General Surgery Department, Monash Health, Melbourne, Australia.

We present the case of a 29-year-old woman who attended a surgical outpatient clinic with symptoms of perianal fissure due to syphilitic infection. This uncommon aetiology of a common condition is often alluded to in textbooks, but little information exists in the scientific literature regarding the pathogenesis, presentation and treatment of fissure-in-ano secondary to syphilis. We present the case and an overview of the topic aimed at surgeons and clinicians who manage patients with perianal pathology. Read More

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November 2018
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TUSKEGEE AND THE HEALTH OF BLACK MEN.

Q J Econ 2018 Feb 2;133(1):407-455. Epub 2017 Aug 2.

University of Tennessee, NBER and IZA.

I14, O15 For forty years, the Tuskegee Study of Untreated Syphilis in the Negro Male passively monitored hundreds of adult black males with syphilis despite the availability of effective treatment. The study's methods have become synonymous with exploitation and mistreatment by the medical profession. To identify the study's effects on the behavior and health of older black men, we use an interacted difference-in-difference-in-differences model, comparing older black men to other demographic groups, before and after the Tuskegee revelation, in varying proximity to the study's victims. Read More

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February 2018

Epidermotropism in Nodular Secondary Syphilis.

Indian J Dermatol 2018 Nov-Dec;63(6):509-511

Department of Dermatology, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.

Nodular secondary syphilis results from the hematogenous and lymphatic dissemination of spirochetes. Clinically, the lesions appear as partially infiltrated plaques or red-violaceous nodules, which can be solitary or multiple. Several hypotheses have been put forward to explain the formation of these infiltrated or granulomatous lesions. Read More

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December 2018

Disease Pattern among Sexually Transmitted Infection Clinic Attendees: A Hospital-Based Study.

Indian J Dermatol 2018 Nov-Dec;63(6):502-505

Department of Pediatrics, Base Hospital, New Delhi, India.

Background: Sexually transmitted infections (STIs) have a definite role in the facilitation of HIV infection, which, in turn, also increases susceptibility to other STIs. Further, the social stigma and secrecy surrounding STIs create difficulty in estimating its true incidence and prevalence.

Objective: The objective of this study was to know the pattern of diseases including different clinical presentations and final diagnosis among the STI clinic attendees. Read More

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December 2018

Etiology of Vaginal/Cervical Discharge Syndrome: Analysis of Data from a Referral Laboratory in Eastern India.

Indian J Dermatol 2018 Nov-Dec;63(6):484-489

Department of VD Serology and Department of STD, Institute of Serology, Kolkata, West Bengal, India.

Context: Sexually transmitted infections (STIs) and reproductive tract infections (RTIs) constitute important public health problem worldwide. Syndromic diagnosis of vaginal/cervical discharge (VCD) is often inaccurate leading to over- or under-treatment.

Aims: This study aimed to ascertain the laboratory-confirmed diagnosis of VCD and their relative frequency in a group of patients presenting to a STI clinic in eastern India and to determine the sensitivity and specificity of clinical diagnosis. Read More

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December 2018

Evaluation of Hemagglutination Assay among Varying Titers of the Venereal Disease Research Laboratory Test.

Indian J Dermatol 2018 Nov-Dec;63(6):479-483

Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India.

Background And Objective: Syphilis, besides being a significant cause of perinatal morbidity and mortality, is a substantial cause of adult morbidity. A discordant serological result can present a diagnostic challenge; hence, a fundamental knowledge about the diagnostic limitations or interpretation of these assays becomes imperative for the clinicians to avoid management dilemma. The study was proposed to see the usefulness and correlation of hemagglutination assay (TPHA) with varying titers of Venereal Disease Research Laboratory (VDRL) test. Read More

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December 2018

Sexual risk behaviour in a cohort of HIV-negative and HIV-positive Rwandan women.

Epidemiol Infect 2018 Dec 3:1-9. Epub 2018 Dec 3.

Department of Pharmacology,University of Gothenburg,Gothenburg,Sweden.

Here we wanted to assess whether sexual risk behaviour differs dependent by human immunodeficiency virus (HIV) status by following 100 HIV- and 137 HIV+ women recruited at two university teaching hospitals in Rwanda. Women were tested for sexually transmitted infections (STIs; trichomoniasis, syphilis, hepatitis B and C) and for reproductive tract infections (RTIs; candidiasis, bacterial vaginosis (BV)) and were interviewed at baseline and 9 months later. BV was the most prevalent infection, while syphilis was the most common STI with a 9-month incidence of 10. Read More

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December 2018
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Awareness of and attitudes to sexually transmissible infections among gay men and other men who have sex with men in England: a qualitative study.

Sex Health 2018 Dec 6. Epub 2018 Dec 6.

Rates of sexually transmissible infections (STIs) have increased over recent years among gay men and other men who have sex with men (MSM) in England and Wales. HIV diagnoses remain high in this group and men with diagnosed HIV are disproportionally affected by STIs. MSM are therefore a priority for health promotion efforts to reduce STIs. Read More

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December 2018
2 Reads

Jarisch-Herxheimer reaction in a patient with syphilis and human immunodeficiency virus infection.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):877-878

Programa de Pós-Graduação Stricto Sensu em Ciências da Saúde, Universidade Federal do Maranhão, São Luís, MA, Brasil.

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October 2017
1 Read

Syphilis in pregnancy, congenital syphilis, and factors associated with mother-to-child transmission in Itapeva, São Paulo, 2010 to 2014.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):819-826

Departamento de Moléstias Infecciosas e Parasitárias, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil.

Introduction: This study describes cases of syphilis in pregnancy (SiP) and congenital syphilis (CS) and identifies factors associated with mother-to-child transmission in patients in Itapeva from January 1, 2010 to December 31, 2014.

Methods: Using SiP and CS notification forms and medical records, a cross-sectional study involving 149 pregnant women was conducted.

Results: Annual SiP detection rates ranged from 16. Read More

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December 2017
1 Read

Prevalence and risk factors of syphilis and human immunodeficiency virus co-infection at a university hospital in Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):813-818

Departamento de Medicina Tropical, Universidade Federal de Pernambuco, Recife, PE, Brasil.

Introduction: The incidence of syphilis has increased since the 1970s.

Methods: This was a descriptive and analytical cross-sectional study with a non-probabilistic sample.

Results: Of 973 patients with human immunodeficiency virus, 179 (18. Read More

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March 2018
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Syphilis in pregnancy and congenital syphilis and their relationship with Family Health Strategy coverage, Goiás, Brazil, 2007-2014: an ecological study.

Epidemiol Serv Saude 2018 Nov 29;27(4):e2018127. Epub 2018 Nov 29.

Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil.

Objective: to analyze the incidence of syphilis in pregnant women (SPW) and congenital syphilis (CS) and the correlation of these indicators with Family Health Strategy (FHS) coverage in Goiás, Brazil, from 2007 to 2014.

Methods: this was an ecological study using Notifiable Diseases Information System (SINAN) data and data from the Health Ministry's Department of Primary Care; Spearman's correlation was used to evaluate the relationship between FHS coverage and syphilis incidence.

Results: SPW incidence increased from 2. Read More

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November 2018
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Treponema pallidum subsp. pallidum DNA and RNA in semen of a syphilis patient without genital or anal lesions. Possible implications for disease transmissibility.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle (WA) USA.

Treponema pallidum subsp. pallidum DNA and RNA were detected in a semen specimen of a syphilis patient with no genital or anal sores and no clinically evident orchitis. No nucleic acids were found in a urine sample of the same patient collected immediately before the semen sample. Read More

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December 2018
1 Read

Integrating HIV testing into syphilis partner services in Mississippi to improve HIV case finding.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Department of Epidemiology, University of Washington, Seattle, WA, USA.

Background: Mississippi (MS) has the 10th highest rate of new HIV infections in the United States. The Mississippi State Department of Health (MSDH) integrated partner HIV testing into syphilis partner services (PS) in 2014, but the effectiveness of this as an HIV case-finding strategy has not been evaluated.

Methods: We identified all early syphilis (primary, secondary, and early latent) case records reported from 7/1/2014-12/31/2016, excluding case records for people concurrently newly diagnosed with HIV. Read More

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December 2018
2 Reads

A Case of Asymptomatic Syphilitic Proctitis.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles.

The incidence of syphilis is increasing. Syphilitic proctitis involving the rectal mucosa often presents with pain on defecation, rectal bleeding, or ulceration. We present a case of asymptomatic syphilitic proctitis diagnosed upon a routine screening colonoscopy. Read More

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December 2018
1 Read

Syphilitic uveitis misdiagnosed as viral retinitis-a misleading history.

J Ophthalmic Inflamm Infect 2018 Dec 4;8(1):22. Epub 2018 Dec 4.

Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, Baba Kharak Singh Marg, New Delhi, 110001, India.

Background: Syphilitic uveitis is an infective uveitis and a great mimicker. Misdiagnosis can lead to delay in the specific treatment resulting in deterioration of uveitis and loss of vision.

Findings: A 38-year-old unmarried female presented with pain, redness, and blurring of vision in the left eye for the last 5 days. Read More

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December 2018
4 Reads

Gonorrhea and syphilis co-infection and related risk factors in HIV patients from Shiraz, South of Iran.

Caspian J Intern Med 2018 ;9(4):397-402

Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: and as an obligate human pathogen are two common causes of sexually transmitted diseases (STDs). The present study aimed to determine the prevalence of and among human immunodeficiency virus (HIV) patients in the southwest Iran.

Methods: This retrospective study was performed from 2004 to 2013, on HIV patients who were tested for detection of gonorrhea and syphilis infection at Shiraz HIV/AIDS Research Center. Read More

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January 2018
1 Read

The Changing Role of Disease Intervention Specialists in Modern Public Health Programs.

Public Health Rep 2018 Nov 30:33354918813549. Epub 2018 Nov 30.

1 Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

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November 2018
1 Read

Congenital Syphilis and the Prozone Phenomenon: A Case Study.

Authors:
Lauren E Spydell

Adv Neonatal Care 2018 Dec;18(6):446-450

Neonatal Intensive Care Unit, Rady Children's Hospital, San Diego, California.

Background: There is a global rise in maternal syphilis and infants born with congenital syphilis.

Clinical Findings: This case report presents a 32-week gestation premature male infant with initial clinical findings significant for respiratory failure as well as blueberry muffin spot rash and hepatosplenomegaly, which are consistent with congenital syphilis.

Primary Diagnosis: This case study is unique in that the diagnosis of congenital neurosyphilis was demonstrated despite negative maternal serology because of the prozone phenomenon. Read More

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December 2018
3 Reads

High rate of seromarkers for HIV, HBV and syphilis among blood donors using confidential unit exclusion, before and after HIV-NAT implementation at a major public blood bank in the Brazilian Amazon.

Transfusion 2018 Nov 30. Epub 2018 Nov 30.

Tropical Pathology and Public Health Institute, Federal University of Goias, Goiania, Brazil.

Background: Confidential unit exclusion (CUE) was introduced in the 1980's as an additional layer to blood safety, before highly specific and sensitive nucleic acid tests (NAT) for HIV were implemented. The utility of CUE-use in settings that have implemented NAT should be evaluated over time.

Study Design, Methods: Cross-sectional retrospective study carried out from June 2010-November 2015, at Manaus Hemocenter (HEMOAM), Amazonas, Brazil that implemented HIV-NAT in 2012. Read More

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November 2018
1 Read

[Late neurosyphilis in a psychiatric hospital].

Zh Nevrol Psikhiatr Im S S Korsakova 2018 ;118(10):19-24

Moscow Regional Clinical Skin and Venereal Diseases Clinic, Moscow, Russia.

Aim: The problem of detection and diagnosis of late forms of neurosyphilis remains relevant and to a large extent concerns the field of psychiatry. The autors study of professional activity of psychiatric hospital in this field with use of clinical and statistical data.

Material And Methods: The article presents modern statistical data on the detection of these forms of syphilis in psychiatric hospitals of the Moscow region in comparison with the indicators of 2008-2010. Read More

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January 2018
1 Read

Mother-to-child transmission prevention of human immunodeficiency virus, syphilis and hepatitis B virus.

Women Birth 2018 Nov 26. Epub 2018 Nov 26.

Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Hunan, China. Electronic address:

Background: China is the first country to initiate a nationwide program for prevention of mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B virus by an integrated approach. However, the progress of this program remains unreported at national or local level for China. Therefore, we performed a hospital-based longitudinal study to assess the integrated prevention effect in Hunan, South-central China. Read More

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November 2018
1 Read
1.696 Impact Factor

IMMUNE RECOVERY UVEITIS-LIKE SYNDROME MIMICKING RECURRENT T-CELL LYMPHOMA AFTER AUTOLOGOUS BONE MARROW TRANSPLANT.

Retin Cases Brief Rep 2018 Nov 26. Epub 2018 Nov 26.

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

Purpose: To report the multimodal imaging findings of immune recovery uveitis mimicking recurrent T-cell lymphoma after autologous bone marrow transplant therapy.

Methods: A 71-year-old man presented with posterior uveitis 6 weeks after chemotherapy and autologous bone marrow transplant for angioimmunoblastic T-cell lymphoma. Multimodal imaging included fluorescein angiography, fundus autofluorescence, and optical coherence tomography. Read More

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November 2018
2 Reads

A historical approach to syphilis infection in Korea.

Acta Med Hist Adriat 2018 12;16(2):185-202

Lab of Bioanthropology, Paleopathology and History of Diseases, Department of Anatomy/Institute of Forensic Science, Seoul National University College of Medicine, Seoul, South Korea.

From the end of the 15th century, syphilis spread worldwide, posing a serious threat to public health. Venereal syphilis has been a major research topic, not only in clinical medicine but also in paleopathology, especially because it is a disease of questionable origin and of high prevalence until the discovery of antibiotics. Syphilis in history has been studied extensively in Europe and the Americas, though less so in Asia. Read More

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December 2018
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Secondary syphilis presenting as erythema multiforme in a HIV-positive homosexual man: a case report and literature review.

Int J STD AIDS 2018 Nov 27:956462418805197. Epub 2018 Nov 27.

1 Dermatology Hospital of Southern Medical University (Guangdong Provincial Dermatology Hospital), Guangzhou, China.

Early syphilis can rarely cause erythema multiforme-type eruptions as well as triggering erythema multiforme (EM). EM-like lesions in secondary syphilis are characterized by clinical features of EM and laboratory tests consistent with secondary syphilis and the skin histology shows predominantly a plasma cell infiltrate with the presence of treponemes. When EM is triggered by early syphilis, the skin histology shows mixed inflammatory cells usually in the absence of treponemes in the skin lesion. Read More

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November 2018
1 Read

Real Time Polymerase Chain Reaction for Hepatitis B Screening in Donor Corneas in the Central Eye Bank of Iran.

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):392-396

Central Eye Bank of Iran, Tehran, Iran.

Purpose: The aim of this study was to report the results of the use of real-time polymerase chain reaction (PCR) for the diagnosis of hepatitis B virus (HBV) infection in cornea donors at the Central Eye Bank of Iran.

Methods: Between 2014 and 2016, all cornea donors that had negative screening serologic results for hepatitis B (HB) surface antigen, HB surface antibody (Ab), hepatitis C virus Ab, human immune deficiency virus Ab, human T-cell leukemia virus Ab, and syphilis, and positive serology for HB core Ab were subjected to real-time PCR with a detection limit of 400 IU/mL to identify HBV DNA. Positive results for HBV DNA were considered occult HBV infections in these donors. Read More

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November 2018
3 Reads

Reaching key populations through key venues: Insights from the Jamaica HIV Prevention Program.

PLoS One 2018 26;13(11):e0206962. Epub 2018 Nov 26.

Department of Medicine, University of North Carolina, North Carolina, United States of America.

Introduction: HIV prevention strategies often include outreach to female sex workers at social venues identified as places where people meet new sexual partners. Patrons and staff at these venues may include female sex workers, their clients, as well as others who have high rates of new sexual partnerships. Few studies have compared HIV/STI among venue-based and general populations, across types of venues, or by sub-group of the venue population. Read More

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November 2018
5 Reads

Limbic encephalitis: Experience of a moroccan center.

Brain Behav 2018 Nov 25:e01177. Epub 2018 Nov 25.

Department of Neurology, Hassan II University Teaching Hospital, Fez, Morocco.

Objectives: Histologically defined as an inflammation-degeneration of limbic structures, limbic encephalitis (LE) is a rare disease and often difficult to diagnose particularly in institutions with limited access to laboratory tests such as antineuronal antibodies or HSV-PCR, and functional imaging. We aimed to describe the demographic, clinical, paraclinical, and etiological features of LE, as well as its medium-term prognosis in Moroccan patients.

Materials And Methods: We collected retrospectively all patients diagnosed with LE in the Department of Neurology of the University Hospital Hassan II of Fez (Morocco) between September 2008 and December 2016. Read More

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November 2018
5 Reads

Field performance evaluation of dual rapid HIV and syphilis tests in three antenatal care clinics in Zambia.

Int J STD AIDS 2018 Nov 25:956462418800872. Epub 2018 Nov 25.

1 Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.

This cross-sectional study of 3212 pregnant women assessed the field performance, acceptability, and feasibility of two dual HIV/syphilis rapid diagnostic tests, the Chembio DPP HIV-syphilis Assay and the SD Bioline HIV/syphilis Duo in antenatal clinics. Sensitivity and specificity for HIV and syphilis were calculated compared to the rapid Determine HIV-1/2 with Uni-Gold to confirm positive results for HIV and the Treponema pallidum particle agglutination assay for syphilis. RPR titers ≥1:4 were used to define active syphilis detection. Read More

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November 2018
4 Reads

Prevalence of Sexually Transmitted Infections (HIV, HBV, HSV-2 and Syphilis) in pregnant women in Ethiopia: Trends over 10 Years (2005-2014).

Int J Infect Dis 2018 Nov 22. Epub 2018 Nov 22.

HIV/AIDS and Tuberculosis Research Directorate, Ethiopian Public Health Institute (EPHI), Addis Ababa, Ethiopia. Electronic address:

Objectives: We determined the trend in sero-prevalence of the major STIs (HIV, HBV, HSV-2 and Syphilis) over ten years (2005-2014) in pregnant women in Ethiopia.

Methods: Pregnant women (15-49 years old) who were enrolled in the ANC based national HIV surveillance were included. Serological tests for HIV, HBV, HSV-2 and Syphilis were done on/plasma samples. Read More

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November 2018
3 Reads

Epidemiology and current control of sexually transmitted infections. The role of STI clinics.

Enferm Infecc Microbiol Clin 2018 Nov 19. Epub 2018 Nov 19.

Servicio Enfermedades Infecciosas, OSI Bilbao-Basurto, Osakidetza, Grupo de estudio de ITS (GeITS) de la SEIMC, Instituto de Investigación Biocruces Bizkaia, Bizkaia, España. Electronic address:

The burden of disease from sexually transmitted infections (STI) undermines sexual and reproductive health and the health of newborn infants. The presence of some STI facilitates the transmission of others, such as HIV, and cause cellular changes that precede some types of cancer. For all these reasons STIs are a first order uncontrolled public health problem. Read More

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November 2018
5 Reads

A case of syphilis presenting with prolonged etiology-unrevealed fever, accompanying activated partial thromboplastin time prolongation.

Authors:
Kazuhiro Yasuo

J Gen Fam Med 2018 Nov 28;19(6):211-214. Epub 2018 Sep 28.

Department of General Internal Medicine National Health organization Asahikawa Medical Center Asahikawa-City Hokkaido Japan.

A 58-year-old woman presenting with 3-week-prolonged fever was referred to our department. Her present history and physical examination results were unremarkable. Her activated partial thromboplastin time (APTT) was prolonged. Read More

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November 2018
2 Reads

Urological Manifestation of Cryptic Severe Psychiatric Illness.

Mil Med 2018 Nov 21. Epub 2018 Nov 21.

Arnot Ogden Medical Center Emergency Medicine Residency Program, 1001 Hoffman St, Elmira, NY.

Penile cellulitis has rarely been reported in the literature and never secondary to self-injury with subsequent sexual activity. It presents a challenging diagnostic situation in that the patient will likely be less than forthcoming about the etiology of his symptoms despite his willingness to seek formal medical attention. We present a case of penile cellulitis secondary to dermatitis artefacta in a severely depressed new submarine sailor. Read More

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November 2018
2 Reads