868 results match your criteria Synovial Sarcoma Imaging


Intraosseous synovial sarcoma of the distal ulna: a case report and review of the literature.

BMC Cancer 2019 Feb 1;19(1):116. Epub 2019 Feb 1.

Department of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

Background: Synovial sarcoma is a relatively rare type of soft tissue sarcoma. The commonly observed symptom is a deep-seated palpable mass accompanied by pain or tenderness. Thus, it is considered a soft tissue sarcoma and rarely occurs primarily in bone. Read More

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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
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http://dx.doi.org/10.1186/s12885-019-5325-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359868PMC
February 2019
3 Reads

Primary Synovial Sarcoma of the Mediastinum with Long-term Follow-up.

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Department of Pulmonary Medicine, Thoracic Center, St. Luke's International Hospital, Japan.

Chest radiography showed a right posterior mass on the mediastinum of an 84-year-old woman. The mass had been growing gradually for four years. Surgical excision was performed, and a pathological examination found the mass to be consistent with primary synovial sarcoma (SS) of the mediastinum. Read More

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http://dx.doi.org/10.2169/internalmedicine.2199-18DOI Listing
January 2019

Diagnostic Imaging and Management of Common Intra-articular and Peri-articular Soft Tissue Tumors and Tumorlike Conditions of the Knee.

J Knee Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Orthopedic Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

Intra-articular (IA) and peri-articular (PA) tumors of the knee are frequently encountered by orthopaedic surgeons. Nonetheless, due to the possibility of great morbidity and potential mortality, it is important to recognize and differentiate between benign and malignant lesions in a timely manner. Therefore, the purpose of this article is to provide a concise, practical, and updated review of commonly encountered IA and PA tumors including intratendinous gout, synovial chondromatosis, schwannoma, pigmented villonodular synovitis, and synovial sarcoma, and a detailed description of differentiating features to include various imaging modalities. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675609
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http://dx.doi.org/10.1055/s-0038-1675609DOI Listing
November 2018
8 Reads

Synovial sarcoma of bone: Sarcoma typically of soft tissues presenting as a primary bone tumor.

Radiol Case Rep 2019 Feb 9;14(2):204-207. Epub 2018 Nov 9.

Department of Sarcoma, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA.

Synovial sarcoma typically presents as periarticular soft tissue mass in adolescent and young adult patients. Very rarely, soft tissue sarcomas may arise primarily within bone posing a significant diagnostic challenge as primary osseous malignancies such as osteosarcoma and metastatic disease are much more common. While tissue sampling with immunohistochemical and genetic testing are required for definitive diagnosis, radiologists and orthopedic oncologists should consider alternate etiologies when typical imaging features of more common bone tumors are not identified. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19300433183046
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http://dx.doi.org/10.1016/j.radcr.2018.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231113PMC
February 2019
10 Reads

[Synovial sarcoma of the right forearm].

Pan Afr Med J 2018 13;30:124. Epub 2018 Jun 13.

Service de Radiologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc.

We report the case of a 60-year old female patient, followed up for hypertensive heart disease for 04 years, presenting to the Dermatological Department with a mass in the right forearm which had evolved and gradually increased in size over the previous year. Clinical examination showed soft rounded, voluminous painless, tumor-like crusted ulcerative lesion measuring 8 cm in large-diameter, fixed with respect to both planes, at the level of the mid-parts of the posterolateral area of the right forearm (A). Standard X-ray showed homogeneous opaque mass with sparing of the opposite cortex (B). Read More

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http://dx.doi.org/10.11604/pamj.2018.30.124.15900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201604PMC
November 2018
3 Reads

Primary malignant peripheral nerve sheath tumor of prostate in a young adult: A case report.

Medicine (Baltimore) 2018 Sep;97(39):e12040

Department of Hematology-Oncology.

Rationale: Prostate sarcoma has been reported to represent 0.7% of primary prostate malignancies. Leiomyosarcoma and rhabdomyosarcoma are the most common sarcomas of the prostate. Read More

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http://dx.doi.org/10.1097/MD.0000000000012040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181477PMC
September 2018
11 Reads

Intra-articular synovial sarcoma in the ankle joint: A case report.

Mol Clin Oncol 2018 Oct 20;9(4):464-466. Epub 2018 Aug 20.

Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan.

Intra-articular primary soft tissue sarcomas are extremely rare. The present case report describes a case of intra-articular synovial sarcoma of the ankle joint. A 51-year-old man presented with complaints of swelling and progressive pain in the right ankle. Read More

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http://dx.doi.org/10.3892/mco.2018.1702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142301PMC
October 2018
1 Read

Left neck undifferentiated sarcoma with synchronous left kidney renal cell carcinoma.

Radiol Case Rep 2018 Oct 19;13(5):1087-1090. Epub 2018 May 19.

University of Texas Medical Branch 301 University Boulevard, Galveston, Texas, 77555, USA.

Parapharyngeal space sarcomas are rare malignancies and most in the reported literature are synovial sarcomas. Here we present the case of a 27-year-old female with a painless, left-sided neck mass who underwent computed tomography and magnetic resonance imaging evaluation which demonstrated a benign appearing mass that upon resection unexpectedly proved to be a high-grade undifferentiated sarcoma with rhabdoid features. Staging computed tomography revealed a synchronous renal cell carcinoma with clear cell and papillary features. Read More

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http://dx.doi.org/10.1016/j.radcr.2018.04.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137406PMC
October 2018
2 Reads

PET in the Diagnostic Management of Soft Tissue Sarcomas of Musculoskeletal Origin.

PET Clin 2018 Oct;13(4):609-621

Keck School of Medicine, University of Southern California (USC), 1520 San Pablo Street, Suite L1600, Los Angeles, CA 90033.

Soft tissue sarcomas (STSs) account for less than 1% of adult solid tumors and about 7% of pediatric malignancies, causing 2% of cancer-related deaths. With the advent of PET-computed tomography (CT), the value of (18) fluorine-2-fluoro-2-deoxy-d-glucose (FDG) PET imaging to improve the management of STSs has been explored. FDG PET imaging has been found useful in restaging and treatment response assessment. Read More

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http://dx.doi.org/10.1016/j.cpet.2018.05.011DOI Listing
October 2018
3 Reads

Surgical management and outcome of synovial sarcoma in the spine.

World J Surg Oncol 2018 Aug 27;16(1):175. Epub 2018 Aug 27.

Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai, 200003, China.

Background: Synovial sarcoma (SS) is a soft tissue sarcoma that rarely occurs in the spine, and a minimal number of cases have been reported in the literature. Spinal SS is challenging in diagnosis and treatment and has a poor prognosis. The aim of this study was to summarize and analyse the clinical features and outcomes of patients with spinal SS. Read More

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http://dx.doi.org/10.1186/s12957-018-1471-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112132PMC
August 2018
25 Reads

An Untypical Case of Gouty Infiltration of Both Peroneal Tendons and a Longitudinal Lesion of the Peroneus Brevis Tendon Mimicking Synovial Sarcoma.

Case Rep Orthop 2018 26;2018:8790916. Epub 2018 Jul 26.

Zentrum für Orthopädie und Unfallchirurgie, Städtisches Klinikum Saarbrücken, Saarbrücken, Germany.

We present a case of a 70-year-old male patient with an untypical gout infiltration of the peroneal tendons mimicking synovial sarcoma. The patient had a negative history of gout at initial presentation in our department. Magnetic resonance imaging of the region revealed a finding highly suspicious for synovial sarcoma of the peroneal tendons. Read More

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http://dx.doi.org/10.1155/2018/8790916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083480PMC
July 2018
2 Reads

Analysis of bone and soft-tissue sarcomas registered during the year 2012 at Tata Memorial Hospital, Mumbai, with clinical outcomes.

Indian J Cancer 2018 Jan-Mar;55(1):37-44

Department of Surgical Pathology, Bone and Soft Tissues, Disease Management Group (DMG), Tata Memorial Hospital, Mumbai, Maharashtra, India.

Introduction: Primary bone and soft tissue sarcomas are rare, but diagnostically and therapeutically challenging group of tumors, requiring multidisciplinary management. There are limited documented studies from multidisciplinary teams , in the form of comprehensive analysis of these tumors, from our country. This study is an analysis of cases of osteosarcomas, Ewing sarcomas (ESs), chondrosarcomas (CSs), and soft-tissue sarcomas (STSs), registered at our institution during 2012. Read More

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http://dx.doi.org/10.4103/ijc.IJC_481_17DOI Listing
November 2018
8 Reads

Retrospective audit of 957 consecutive F-FDG PET-CT scans compared to CT and MRI in 493 patients with different histological subtypes of bone and soft tissue sarcoma.

Clin Sarcoma Res 2018 9;8. Epub 2018 Apr 9.

1Oxford Sarcoma Service (OxSarc), Oxford University Hospitals Foundation Trust, Oxford, OX3 7LE UK.

Background: The use of F-FDG PET-CT (PET-CT) is widespread in many cancer types compared to sarcoma. We report a large retrospective audit of PET-CT in bone and soft tissue sarcoma with varied grade in a single multi-disciplinary centre. We also sought to answer three questions. Read More

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http://dx.doi.org/10.1186/s13569-018-0095-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086048PMC
April 2018
2 Reads

Aggressive myxoinflammatory fibroblastic sarcoma with multiple site metastases.

BMJ Case Rep 2018 Jul 18;2018. Epub 2018 Jul 18.

Department of Pathology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare soft tissue sarcoma which was initially observed in acral sites and characterised by spindle cells, pleomorphic bizarre cells and distinctive large Reed-Sternberg-like cells admixed with an intense inflammatory cell infiltrates. MIFS manifests as a slow growing often superficial lesion which can be mistaken as infectious or chronic inflammatory process or benign tumours such as nodular fasciitis, giant cell tumour of tendon sheath or synovial pseudocyst. We report a rare presentation of a MIFS in a 38-year-old man with extensive local spread from subcutaneous tissue to the ankle joint and bones as well as multiple synchronous metastases to lung, sixth rib and vertebra. Read More

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http://dx.doi.org/10.1136/bcr-2018-224259DOI Listing
July 2018
2 Reads

Treatment of cardiac synovial sarcoma: experience of two cases.

J Cardiothorac Surg 2018 Jul 3;13(1):84. Epub 2018 Jul 3.

Department of Cardiovascular Sciences, Catholic University of Sacred Heart, Rome, Italy.

Background: Primary heart sarcomas are exceedingly rare tumors. Among primary cardiac sarcomas, synovial sarcoma is one of the rarest, involving cardiac cavities or pericardium.

Case Presentation: Two cases of synovial sarcoma are presented with the clinical course and therapy. Read More

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http://dx.doi.org/10.1186/s13019-018-0771-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029359PMC
July 2018
10 Reads

α-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.

Cancer Sci 2018 Jul 27;109(7):2302-2309. Epub 2018 Jun 27.

Radiation and Cancer Biology Team, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Synovial sarcoma (SS) is a rare yet refractory soft-tissue sarcoma that predominantly affects young adults. We show in a mouse model that radioimmunotherapy (RIT) with an α-particle emitting anti-Frizzled homolog 10 (FZD10) antibody, synthesized using the α-emitter radionuclide astatine-211 ( At-OTSA101), suppresses the growth of SS xenografts more efficiently than the corresponding β-particle emitting anti-FZD10 antibody conjugated with the β-emitter yettrium-90 ( Y-OTSA101). In biodistribution analysis, At was increased in the SS xenografts but decreased in other tissues up to 1 day after injection as time proceeded, albeit with a relatively higher uptake in the stomach. Read More

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http://doi.wiley.com/10.1111/cas.13636
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http://dx.doi.org/10.1111/cas.13636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029834PMC
July 2018
16 Reads

Primary pulmonary synovial sarcoma: A reappraisal.

J Cancer Res Ther 2018 Apr-Jun;14(3):481-489

Department of Pulmonary Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Synovial sarcoma (SS) is a malignant mesenchymal tumor with variable epithelial differentiation that affects mostly young adults and can arise at any anatomic site. Primary intrathoracic SS is very rare accounting for <0.5% of all lung tumors. Read More

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http://dx.doi.org/10.4103/0973-1482.204883DOI Listing
October 2018
2 Reads

Primary cardiac synovial sarcoma of the interatrial septum.

J Card Surg 2018 Jul 10;33(7):391-392. Epub 2018 Jun 10.

Department of Cardiac Surgery, University Hospital of Antwerp, Edegem, Antwerp, Belgium.

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http://dx.doi.org/10.1111/jocs.13733DOI Listing
July 2018
4 Reads

Primary Pleuropulmonary Synovial Sarcoma: A Case.

Case Rep Pulmonol 2018 4;2018:5190271. Epub 2018 Apr 4.

Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.

Primary pleuropulmonary synovial sarcoma is extremely rare. The diagnosis can only be made after having eliminated an extrapleuropulmonary localization in the past and at the time of diagnosis. Our presentation is about a 40-year-old woman having a cough and dyspnea since three weeks ago; imaging had showed a left pleurisy with pleuropulmonary process. Read More

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http://dx.doi.org/10.1155/2018/5190271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904799PMC
April 2018
1 Read

FISH analysis of selected soft tissue tumors: Diagnostic experience in a tertiary center.

Asia Pac J Clin Oncol 2019 Feb 28;15(1):38-47. Epub 2018 May 28.

Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

Aim: Fluorescence in situ hybridization (FISH) is an important ancillary tool for the classification of bone/soft tissue (BST) tumors. The aim of this study was to evaluate the contribution of FISH to the final classification of common BST entities in the molecular pathology department of the Royal Prince Alfred Hospital (RPAH), which is one of the most important referral centers for the management of sarcomas in Australia.

Methods: All routine diagnostic FISH tests performed on BST formalin-fixed paraffin embedded (FFPE) tissue specimens at the RPAH in a 5-year period (February, 2010-November, 2015) were reviewed. Read More

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http://dx.doi.org/10.1111/ajco.12980DOI Listing
February 2019
6 Reads

Shoulder Lesion in a 69 Year Old Woman.

J Long Term Eff Med Implants 2018 ;28(1):47-53

Division of Adult Reconstruction, SUNY Downstate Medical Center, Brooklyn, New York; Department of Orthopaedic Surgery and Rehabilitation Medicine, SUNY Downstate Medical Center, Brooklyn, New York.

Milwaukee Shoulder Syndrome (MSS) is a painful progressive arthropathy in which hydroxyapatite crystal deposition in synovial tissue induces lysosomal release of collagenase and neutral proteases. These enzymes are destructive to periarticular tissue, including the synovium, articular cartilage, rotator cuff muscles, and the intrasynovial cortical bone. MSS predominantly occurring in women (90%) over the age of 70 years of age with a clinical history marked by recurrent joint effusions and pain, which classically worsens at night. Read More

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http://dx.doi.org/10.1615/JLongTermEffMedImplants.2017020612DOI Listing
January 2018
13 Reads

Synovial Haemangioma of the Elbow: A rare paediatric case and imaging dilemma.

Sultan Qaboos Univ Med J 2018 Feb 4;18(1):e93-e96. Epub 2018 Apr 4.

Department of Orthopaedics & Traumatology, National University of Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Synovial haemangiomas are rare benign vascular proliferations arising in synovium-lined surfaces. While the knee is by far the joint most commonly involved, this condition can also occur in the elbow. We report an eight-year-old boy who presented to the National University of Malaysia Medical Centre, Kuala Lumpur, Malaysia, in 2016 with a left elbow swelling of one year's duration. Read More

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http://dx.doi.org/10.18295/squmj.2018.18.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892820PMC
February 2018
2 Reads

Review with novel markers facilitates precise categorization of 41 cases of diagnostically challenging, "undifferentiated small round cell tumors". A clinicopathologic, immunophenotypic and molecular analysis.

Ann Diagn Pathol 2018 Jun 29;34:1-12. Epub 2017 Nov 29.

Pathology Department, University of Valencia, Valencia, Spain.

Background: Despite extensive immunohistochemical (IHC) and molecular studies combined with morphologic findings, a group of round/ovoid cell tumors histologically similar to Ewing sarcomas (ES) but lacking EWSR1-rearrangements may remain unclassifiable.

Design: We retrospectively analyzed 41 Ewing-like tumors (formalin-fixed, paraffin-embedded) previously determined as negative or non-informative for EWSR1-rearrangements by FISH and/or RT-PCR. A new histopathology revision and additional IHC and molecular analyses were carried out in order to investigate whether additional IHC and/or molecular testing in combination with the morphological findings may help in reaching a definitive diagnosis. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2017.11.011DOI Listing
June 2018
8 Reads

Preoperative evaluation of the efficacy of radio-hyperthermo-chemotherapy for soft tissue sarcoma in a case series.

PLoS One 2018 16;13(4):e0195289. Epub 2018 Apr 16.

Department of Orthopaedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.

Purpose: Radio-hyperthermo-chemo (RHC) therapy, which combines radiotherapy, hyperthermia, and chemotherapy, for malignant soft tissue tumors has been introduced with the aim of decreasing the possibility of local recurrence after surgery. To avoid unnecessary neoadjuvant therapy and to plan the appropriate surgical treatment, surveillance of RHC therapeutic efficacy during treatment is necessary. In this study, we determined the optimal response criteria to evaluate the efficacy of RHC by comparing preoperative images before and after RHC with pathological evaluation of necrosis in the resected tumor. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195289PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901917PMC
July 2018
8 Reads

Evaluation of recurrence of musculoskeletal tumors with thallium-201 scintigraphy plus SPECT/CT in pediatric population.

Bol Med Hosp Infant Mex 2018 ;75(1):31-40

Departamento de Medicina Nuclear e Imagen Molecular, Instituto Nacional de Cancerología. Ciudad de México, México.

Background: Imaging studies, particularly simple and contrast-enhanced tomography, constitute the first diagnostic approach to detect recurrence of musculoskeletal tumors. The aim of the present retrospective study was to demonstrate the usefulness of scintigraphy plus SPECT/CT (single photon emission computed tomography) with thallium-201 (Tl) in the evaluation of malignant musculoskeletal tumors with suspicion of recurrence or metastatic disease.

Methods: Eight weeks after the last therapy, 72 scintigraphy and SPECT/CT studies were performed to assess regional recurrence and metastatic disease in 42 patients with different types of malignant musculoskeletal tumors, such as osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, retinoblastoma, synovial sarcoma, and Wilms tumor at the Hospital Infantil de México Federico Gómez. Read More

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http://dx.doi.org/10.24875/BMHIM.M18000004DOI Listing
January 2018
4 Reads

Synovial sarcoma of the transverse colon: a rare cause of intussusception.

BMJ Case Rep 2018 Mar 30;2018. Epub 2018 Mar 30.

Colon and Rectal Surgery, St. Joseph Mercy Ann Arbor, Ypsilanti, Michigan, USA.

We report a third case of a primary intramural synovial sarcoma of the lower gastrointestinal tract. A 50-year-old woman presented with hematochezia, dizziness and shortness of breath. CT imaging revealed a transverse colo-colonic intussusception with a colonic mass serving as a lead point. Read More

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http://dx.doi.org/10.1136/bcr-2018-224198DOI Listing
March 2018
2 Reads

ATYPICAL PRESENTATION OF SOFT TISSUE SARCOMA.

Ulster Med J 2017 09 12;86(3):204-205. Epub 2017 Sep 12.

Royal Victoria Hospital, 274 Grosvenor Road, Belfast BT12 6BA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849985PMC
September 2017
14 Reads

Primary renal synovial sarcoma: A case report and literature review.

J Cancer Res Ther 2018 ;14(Supplement):S267-S269

Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.

Synovial sarcomas (SSs) are very rare, poorly studied tumors that generally occurs around joint and muscle tendons. Primary SSs of the kidney are even rarer, accounting for <2% of all malignant renal tumors. We report the case of a 44-year-old man who was diagnosed with primary renal SS on the basis of imaging, histopathological, and immunohistochemical examination. Read More

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http://dx.doi.org/10.4103/0973-1482.181170DOI Listing
August 2018
1 Read

Primary Synovial Sarcoma of the Kidney: A Rare Presentation.

Urology 2018 Jun 19;116:e7-e8. Epub 2018 Mar 19.

Department of Pathology, The Gujarat Cancer and Research Institute, Ahmedabad, India.

Primary renal synovial sarcoma (PRSS) is a rare entity. It should be considered as one of the differential diagnoses of spindle cell tumors of the kidney. Immunohistochemistry and genetic translocation studies should be used to confirm the diagnosis. Read More

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http://dx.doi.org/10.1016/j.urology.2017.12.017DOI Listing
June 2018
1 Read

Detection of fusion gene in cell-free DNA of a gastric synovial sarcoma.

World J Gastroenterol 2018 Feb;24(8):949-956

Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.

Synovial sarcoma (SS) is genetically characterized by chromosomal translocation, which generates fusion transcripts. Although SS can occur in any body part, primary gastric SS is substantially rare. Here we describe a detection of the fusion gene sequence of gastric SS in plasma cell-free DNA (cfDNA). Read More

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http://dx.doi.org/10.3748/wjg.v24.i8.949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829158PMC
February 2018
1 Read

Synovium as a widespread pathway to the adjacent joint in undifferentiated high-grade pleomorphic sarcoma of the tibia: A case report.

Medicine (Baltimore) 2018 Feb;97(8):e9870

Department of Radiology, the Third Hospital of Hebei Medical University.

Rationale: Undifferentiated high-grade pleomorphic sarcoma (UPS), originated from bone, is a rare tumor, accounting for 2% to 5% of all primary maligment bone neoplasms. Skip lesion can be found in undifferentiated high-grade pleomorphic sarcoma of bone (UPS-B). However, the direct invasion across the articular synovium to bone has not been reported previously. Read More

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http://dx.doi.org/10.1097/MD.0000000000009870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842000PMC
February 2018
7 Reads

Synovial sarcoma of the maxillary sinus: an extremely rare case with excellent response to chemotherapy.

Onco Targets Ther 2018 23;11:483-488. Epub 2018 Jan 23.

Department of Otorhinolaryngology - Head and Neck Surgery, Keio University, School of Medicine.

This paper presents an extremely rare case of synovial sarcoma arising from the maxillary sinus, which resulted in a clinically complete response to chemotherapy. Synovial sarcoma is a rare soft tissue malignant tumor, most commonly affecting the extremities. While ~10% occur in the head and neck region, synovial sarcoma of the sinonasal tract is extremely rare, with only 11 cases having been reported previously. Read More

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http://dx.doi.org/10.2147/OTT.S151473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789048PMC
January 2018
4 Reads

Postradiation Synovial Sarcoma of the Common Bile Duct: A Previously Unreported Anatomic Site.

Int J Surg Pathol 2018 Aug 16;26(5):469-474. Epub 2018 Jan 16.

1 Instituto Nacional de Cancerología, México City, México.

Synovial sarcoma is a ubiquitous neoplasm predominantly affecting soft tissues of young adults of any gender; few cases have been described in the digestive system, mostly in the stomach. The (X;18)(p11.2; q11. Read More

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http://dx.doi.org/10.1177/1066896917752863DOI Listing
August 2018
3 Reads

Chronic Thigh Pain in a Young Adult Diagnosed as Synovial Sarcoma: A Case Report.

PM R 2018 Sep 10;10(9):969-973. Epub 2018 Jan 10.

Carolina Neurosurgery and Spine Associates, 9735 Kincey Ave, #300, Huntersville, NC 28078(†). Electronic address:

Synovial sarcoma is a slow-growing, intermediate- to high-grade neoplasm with extensive metastatic potential. Accurate diagnosis of synovial sarcoma may pose a challenge to providers because of its indolent growth and variable presentation. The findings of a soft-tissue, periarticular mass with calcifications in a young patient are highly suggestive of synovial sarcoma. Read More

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http://dx.doi.org/10.1016/j.pmrj.2017.12.009DOI Listing
September 2018
3 Reads

[Villonodular synovitis of the knee: about 20 cases].

Pan Afr Med J 2017 27;28:86. Epub 2017 Sep 27.

Service de Traumatologie Orthopédie de l'Hôpital Militaire Avicenne, Marrakech, Maroc.

Pigmented villonodular synovitis (PVNS) is a rare benign proliferation of synovial joints, serous bursa, tendinous sheaths of unknown etiopathogeny. We here report 20 cases of PVNS of the knee recorded at the Avicenne Military Hospital, Marrakech over a period of 9 years, from January 2000 to December 2009. This study aimed to identify the specific features of this lesion and to examine its anatomoclinic and prognostic aspects. Read More

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http://dx.doi.org/10.11604/pamj.2017.28.86.9507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724938PMC
December 2017
9 Reads

Synovial Sarcoma With Intracranial Metastasis as the Site of Reoccurrence.

Am J Med Sci 2017 Nov 15;354(5):523-526. Epub 2017 Mar 15.

Internal Medicine, Saint Joseph's Regional Medical Center, Paterson, New Jersey.

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http://dx.doi.org/10.1016/j.amjms.2017.03.019DOI Listing
November 2017
3 Reads

Primary Pleuropulmonary Synovial Sarcoma on Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Scan.

Indian J Nucl Med 2017 Oct-Dec;32(4):340-342

Department of Radiology Imaging Services, Health Care Global Cancer Centre, Ahmedabad, Gujarat, India.

Primary pleuropulmonary synovial sarcoma, a mesenchymal tumor of lung and pleura, is very rare and highly aggressive condition among the primary lung malignancies. As role of fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) has been established in lung malignancies in terms of staging, restaging, biopsy guidance, and treatment response evaluation, there is also role of FDG PET-contrast-enhanced CT (CECT) to raise suspicion or increase confidence in reporting of sarcomatous lung malignancy by studying characteristics of CECT scan features. We present a case of a 57-year-old female patient having large lung mass, who underwent FDG PET-CT scan and findings raised strong suspicious of noncarcinomatous pattern of lung mass and may have sarcomatous primary lung malignancy which was later proven on histopathological and immunohistochemistry report. Read More

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http://www.ijnm.in/text.asp?2017/32/4/340/216571
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http://dx.doi.org/10.4103/ijnm.IJNM_82_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672758PMC
November 2017
2 Reads

Synovial Sarcoma of the Digits: A Case Report of an Unplanned Excision.

J Foot Ankle Surg 2018 Mar - Apr;57(2):388-392. Epub 2017 Nov 3.

Associate Professor, Department of Pathology, University of Notre Dame, Fremantle, WA, Australia.

Synovial sarcoma is a rare occurrence in the lower extremity, although the presenting symptoms can mimic those of other more common and benign musculoskeletal pathologies. We present the case of a patient who was originally thought to have a Morton's neuroma or ganglionic cyst. The correct diagnosis, synovial sarcoma, was determined only after an unplanned excision. Read More

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http://dx.doi.org/10.1053/j.jfas.2017.07.017DOI Listing
September 2018
14 Reads

Neoplastic Pericardial Disease.

Cardiol Clin 2017 Nov 6;35(4):589-600. Epub 2017 Sep 6.

Department of Cardiovascular Diseases, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA; Division of Cardiac Radiology, Department of Radiology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.

Pericardial tumors are rare lesions that include a range of neoplastic conditions that may arise within the pericardium or metastasize to involve it secondarily. Understanding the spectrum of lesions that are included in the differential diagnosis of a pericardial mass-lesion is critical to making timely, accurate diagnoses and getting the appropriate therapy should one be necessary. This review summarizes the radiologic and pathologic findings of the most commonly encountered of these entities. Read More

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http://dx.doi.org/10.1016/j.ccl.2017.07.011DOI Listing
November 2017
13 Reads

Primary Cystic Pleuropulmonary Synovial Sarcoma Presenting as Recurrent Pneumothorax.

Case Rep Oncol 2017 May-Aug;10(2):660-665. Epub 2017 Jul 14.

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.

Primary pleuropulmonary synovial sarcomas are quite rare, representing 0.1-0.5% of all pulmonary malignancies. Read More

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http://dx.doi.org/10.1159/000478845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567016PMC
July 2017
6 Reads

The Influential Role of BCL2 Family Members in Synovial Sarcomagenesis.

Mol Cancer Res 2017 12 29;15(12):1733-1740. Epub 2017 Aug 29.

Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, Utah.

Synovial sarcomas are deadly soft tissue malignancies associated with t(X;18) balanced chromosomal translocations. Expression of the apoptotic regulator BCL2 is prominent in synovial sarcomas and has prompted the hypothesis that synovial sarcomagenesis may depend on it. Herein, it is demonstrated that overexpression enhances synovial sarcomagenesis in an animal model. Read More

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816685PMC
December 2017
17 Reads

Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls.

Surg Pathol Clin 2017 Sep 29;10(3):705-730. Epub 2017 Jun 29.

Department of Pathology, Azienda ULSS2 Marca Trevigiana, Treviso, Italy; Department of Medicine, University of Padua School of Medicine, Padua, Italy. Electronic address:

Primary bone sarcomas represent extremely rare entities. The use of now abolished labels, such as malignant fibrous histiocytoma and hemangiopericytoma, has significantly hampered the chance of identifying specific entities. It is now accepted that a broad variety of mesenchymal malignancies most often arising on the soft tissue may actually present as primary bone lesions. Read More

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http://dx.doi.org/10.1016/j.path.2017.04.013DOI Listing
September 2017
9 Reads

Nonrhabdomyosarcoma soft tissue sarcoma (NRSTS) in pediatric and young adult patients: Results from a prospective study using limited-margin radiotherapy.

Cancer 2017 Nov 31;123(22):4419-4429. Epub 2017 Jul 31.

Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.

Background: Indications for and delivery of adjuvant therapies for pediatric nonrhabdomyosarcoma soft tissue sarcoma (NRSTS) have been derived largely from adult studies; therefore, significant concern remains regarding radiation exposure to normal tissue. The authors report long-term treatment outcomes and toxicities for pediatric and young adult patients with high-grade NRSTS who were treated on a prospective trial using limited-margin radiotherapy.

Methods: Sixty-two patients (ages 3-22 years) with predominantly high-grade NRSTS requiring radiation were treated on a phase 2 institutional study of conformal external-beam radiotherapy and/or brachytherapy using a 1. Read More

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http://dx.doi.org/10.1002/cncr.30793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673566PMC
November 2017
24 Reads

Biphasic synovial sarcoma of the epiglottis: Case report and literature review.

Auris Nasus Larynx 2018 Jun 6;45(3):617-621. Epub 2017 Jul 6.

Department of Otolaryngology, Head and Neck Surgery, University Hospital Ulm, Frauensteige 12, 89075 Ulm, Germany.

Synovial sarcomas are rare malignant tumors supposed to arise from pluripotent mesenchymal stem cells predominantly affecting the deep soft tissue of the lower and upper extremities in young adults. The occurrence of this tumor entity in the head and neck is very uncommon and hence, timely diagnosis and treatment of synovial sarcoma in this region remain a challenge. We describe the clinical and molecular pathological features of a biphasic synovial sarcoma of the epiglottis, a site where the primary manifestation of this tumor entity has not been documented to date. Read More

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http://dx.doi.org/10.1016/j.anl.2017.06.007DOI Listing
June 2018
9 Reads

Synovial sarcoma mimicking benign peripheral nerve sheath tumor.

Skeletal Radiol 2017 Nov 8;46(11):1463-1468. Epub 2017 Jul 8.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit St, Boston, MA, 02114, USA.

Objective: To assess the radiographic and clinicopathologic features of synovial sarcoma of the nerve that were clinically or radiologically interpreted as benign peripheral nerve sheath tumor.

Materials And Methods: Five patients with synovial sarcoma arising from the peripheral nerve and interpreted clinically and radiologically as peripheral nerve sheath tumors were identified. Clinicopathologic and imaging features were evaluated. Read More

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http://dx.doi.org/10.1007/s00256-017-2710-xDOI Listing
November 2017
15 Reads

[Primary pharynx synovial sarcoma: a case report].

Hua Xi Kou Qiang Yi Xue Za Zhi 2017 Apr;35(2):221-222

Dept. of Oral and Maxillofacial Surgery, Stomatological Hospital of Kunming Medical University, Kunming 650000, China.

A case of primary pharynx synovial sarcoma was reported in this paper. A 15-year-old male patient experienced painless pharyngeal swelling that gradually proliferated for 1 month. Special examination showed an 8 cm × 4 cm × 3 cm tumor located in the left pharynx and the supratonsillar crypt. Read More

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http://dx.doi.org/10.7518/hxkq.2017.02.021DOI Listing
April 2017
5 Reads

Monophasic synovial sarcoma of the greater omentum: case report and review of literature.

Ann R Coll Surg Engl 2017 Jul;99(6):e172-e173

General Surgery Department, Hospital Universitario Insular de Gran Canaria , Las Palmas , Spain.

Synovial sarcoma is a malignant spindle cell neoplasm normally arising from tissues around joints, bursa and tendon sheaths. Several reports involving the gastrointestinal tract, mainly the oesophagus and stomach, have been documented; however, the omentum remains an extremely unusual location. Monophasic type is composed exclusively of spindle cells arranged in fascicles. Read More

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http://dx.doi.org/10.1308/rcsann.2017.0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696984PMC
July 2017
13 Reads

Synovial Sarcoma of the Head and Neck: A Single Institution Review.

Sarcoma 2017 5;2017:2016752. Epub 2017 Jun 5.

Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

Background: The prognosis and clinical characteristics of head and neck synovial sarcomas (HNSS) are unclear. Herein, we present an update using a cohort of patients treated at our institution.

Methods: We performed a retrospective chart review of 44 patients diagnosed with primary HNSS between March 1990 and June 2012. Read More

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http://dx.doi.org/10.1155/2017/2016752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474548PMC
June 2017
15 Reads

Malignant tumours of the foot and ankle.

EFORT Open Rev 2017 May 11;2(5):261-271. Epub 2017 May 11.

Laboratoire d'anatomie et cytologie pathologiques, Institut Universitaire du Cancer de Toulouse- Oncopole, 1 avenue Irène Joliot-Curie. 31059 Toulouse Cedex 9, France.

Most of tumours of the foot are tumour-like (synovial cyst, foreign body reactions and epidermal inclusion cyst) or benign conditions (tenosynovial giant cells tumours, planta fibromatosis). Malignant tumours of the soft-tissue and skeleton are very rare in the foot and their diagnosis is often delayed with referral to specialised teams after initial inappropriate procedures or unplanned excisions. The adverse effect of these misdiagnosed tumours is the increasing rate of amputation or local recurrences in the involved patients. Read More

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http://dx.doi.org/10.1302/2058-5241.2.160078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467685PMC
May 2017
8 Reads

Primary cardiac synovial sarcoma and dual-source cardiac computed tomography findings.

Acta Cardiol 2017 Apr 6;72(2):228-229. Epub 2017 Mar 6.

a Department of Medical Imaging , Huai'an First People's Hospital, Nanjing Medical University , Jiangsu , China.

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http://dx.doi.org/10.1080/00015385.2017.1291201DOI Listing
April 2017
6 Reads