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    Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients.
    World J Crit Care Med 2017 Feb 4;6(1):28-36. Epub 2017 Feb 4.
    Thu AN Nguyen, Yasmine Ali Abdelhamid, Leeanne S Chapple, Adam M Deane, Discipline of Acute Care Medicine, University of Adelaide, Adelaide 5005, Australia.
    Nutrient ingestion induces a substantial increase in mesenteric blood flow. In older persons (aged ≥ 65 years), particularly those with chronic medical conditions, the cardiovascular compensatory response may be inadequate to maintain systemic blood pressure during mesenteric blood pooling, leading to postprandial hypotension. In older ambulatory persons, postprandial hypotension is an important pathophysiological condition associated with an increased propensity for syncope, falls, coronary vascular events, stroke and death. Read More

    Selective use of the electrocardiogram in pediatric preparticipation athletic examinations among pediatric primary care providers.
    Ann Noninvasive Electrocardiol 2017 Feb 21. Epub 2017 Feb 21.
    Division of Cardiology, Children's National Health System, Washington, DC, USA.
    Objectives: Recent literature examining insurance administrative data suggests that a selective approach, with concurrent history and physical exam (H&P), for obtaining an electrocardiogram (ECG) as a part of a preparticipation examination (PPE) for pediatric athletes is commonly used in the primary care setting demonstrating a high rate of disease detection. We sought to understand practice patterns of providers with regard to usage of ECG as a part of PPE.

    Methods: Utilizing an online survey, we queried primary care providers regarding their practice patterns, rationale, and concerns regarding use of ECGs as a part of the PPE. Read More

    Balloon Valvuloplasty of Tricuspid Stenosis: A Retrospective Study of 5 Labrador Retriever Dogs.
    J Vet Intern Med 2017 Feb 21. Epub 2017 Feb 21.
    William R. Pritchard Veterinary Medial Teaching Hospital, UC Davis School of Veterinary Medicine, Davis, CA.
    Background: There are limited reports of severe tricuspid valve stenosis in dogs and limited data regarding treatment and outcome.

    Objective: To evaluate clinical signs, echocardiographic features, and outcome of balloon valvuloplasty (BV) in dogs with severe tricuspid valve stenosis (TVS) in which BV was attempted.

    Animals: Five client-owned dogs with severe TVS. Read More

    A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction.
    Circ Res 2017 Feb 20. Epub 2017 Feb 20.
    Institute for Genetics of Heart Diseases, University Hospital Muenster
    Rationale: Familial sinus node and atrioventricular (AV) conduction dysfunction is a rare disorder that leads to paroxysmal dizziness, fatigue and syncope due to a temporarily or permanent reduced heart rate. To date, only a few genes for familial sinus and/or AV conduction dysfunction are known and the majority of cases remain etiologically unresolved. Objective: We aim to identify the disease gene in a large three-generation family (n=25) with autosomal dominant sinus node dysfunction (SND) and AV block (AVB) and to characterise the mutation-related pathomechanisms in familial SND+AVB. Read More

    Comparison of short head-up tilt test with conventional protocol after omission of nonmedicated phase in children and young adults.
    Adv Biomed Res 2016 29;5:207. Epub 2016 Dec 29.
    Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran.
    Background: Syncope is an important and common clinical condition, and the neurally mediated syncope is the most frequent type of syncope. Tilt testing is considered as a first-line diagnostic test.

    Materials And Methods: We conducted the conventional and modified tilt test on 200 subjects in the age range of 5-20 years. Read More

    Neurological Assessment and Nerve Conduction Study Findings in 22 Patients with Alkaptonuria from Jordan.
    Neurol Int 2016 Nov 5;8(4):6841. Epub 2017 Jan 5.
    Special Surgery Faculty of Medicine, Mutah University , Jordan.
    Alkaptonuria is a rare metabolic disease characterised by accumulative deposition of homogentisic acid in the connective tissue of the body. This results in early degeneration of tendons, cartilages, heart valves, and other tissues. The main objective of the study is to examine the possibility of the nervous system involvement in patients with alkaptonuria The sample consists of two groups; 22 patients with AKU and 20 controls. Read More

    Common Carotid Artery Occlusion Presenting with Recurrent Syncopal Episodes.
    Neurol Int 2016 Nov 5;8(4):6822. Epub 2016 Jan 5.
    Department of Vascular Surgery, John Hunter Hospital , New Lambton, Australia.
    Symptomatic common carotid artery (CCA) occlusion is an uncommon occurrence that may require surgical intervention. We aim to describe a case of CCA occlusion that presented with the unusual symptom of recurrent syncope. A 69-year-old lady presented with a history of recurrent syncopal episodes and amaurosis fugax associated with left leg weakness. Read More

    Mid-Term Follow-up of School-Aged Children With Borderline Long QT Interval.
    Circ J 2017 Feb 18. Epub 2017 Feb 18.
    Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center.
    Background: There are no definitive diagnostic criteria or follow-up strategies for long QT syndrome (LQTS) in children with a borderline long QT interval (b-LQT).Methods and Results:We retrospectively evaluated the clinical course, genetic testing results, corrected QT interval (QTc), and LQTS score of 59 school-aged children (5-18 years old) with a b-LQT (400≤QTc<500 ms). Syncope, but neither aborted cardiac arrest nor sudden cardiac death, occurred in 2 patients during the follow-up (6±3. Read More

    Cardiac Phenotype and Long Term Prognosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia Patients with Late Presentation.
    Heart Rhythm 2017 Feb 12. Epub 2017 Feb 12.
    Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:
    Background: The clinical profile of Arrhythmogenic Right Ventricular Cardiomyopathy/ Dysplasia patients with late presentation (ARVC/D) is unknown.

    Objective: To characterize the genotype, cardiac phenotype and long term outcomes of ARVC/D patients with late presentation (age≥ 50 years at diagnosis) METHODS: 502 patients with ARVC/D diagnosis from Johns Hopkins and Utrecht registries were studied and long term clinical outcomes ascertained.

    Results: Late presentation was seen in 104 (21%) patients (38% PKP2 carriers) with 3% ≥ 65 years at diagnosis. Read More

    Arrhythmogenic right ventricular dysplasia: Atypical clinical presentation.
    Rev Port Cardiol 2017 Feb 14. Epub 2017 Feb 14.
    Serviço de Endocrinologia, Hospital de Santa Maria/CHLN, Lisboa, Portugal; Departamento de Medicina, Hospital de Santa Maria/CHLN, Faculdade de Medicina de Lisboa, Lisboa, Portugal. Electronic address:
    A 67-year-old man was admitted to our hospital after episodes of syncope preceded by malaise and diffuse neck and chest discomfort. No family history of cardiac disease was reported. Laboratory workup was within normal limits, including D-dimers, serum troponin I and arterial blood gases. Read More

    Temperament and Character Personality Dimensions in Nitrate-Tilt-Induced Vasovagal Syncope Patients.
    Hellenic J Cardiol 2017 Feb 14. Epub 2017 Feb 14.
    Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples - Monaldi Hospital, Naples, Italy.
    Introduction: Vasovagal syncope (VVS) is a clinical syndrome characterized by transient loss of consciousness and postural tone that is due to a temporary and spontaneously self-terminating global cerebral hypoperfusion. It is known that personality modulates the individual's sensitivity to stressors, and emotional arousal and psychologic uncertainty are conditions contributing to vasodepressor syncope. Therefore it is postulated that personality characteristics of VVS patients could have a role in the pathophysiology of VVS. Read More

    Estimating the Cost of Care for Emergency Department Syncope Patients: Comparison of Three Models.
    West J Emerg Med 2017 Feb 20;18(2):253-257. Epub 2017 Jan 20.
    Oregon Heath & Science University, Center for Policy and Research in Emergency Medicine, Portland, Oregon.
    Introduction: We sought to compare three hospital cost-estimation models for patients undergoing evaluation for unexplained syncope using hospital cost data. Developing such a model would allow researchers to assess the value of novel clinical algorithms for syncope management.

    Methods: We collected complete health services data, including disposition, testing, and length of stay (LOS), on 67 adult patients (age 60 years and older) who presented to the emergency department (ED) with syncope at a single hospital. Read More

    Targets and End Points in Cardiac Autonomic Denervation Procedures.
    Circ Arrhythm Electrophysiol 2017 Feb;10(2):e004638
    From the Unidade Clínica de Arritmia, Heart Institute, University of São Paulo Medical School, Brazil.
    Background: Autonomic denervation is an alternative approach for patients with symptomatic bradycardia. No consensus exists on the critical targets and end points of the procedure. The aim of this study was to identify immediate end points and critical atrial regions responsible for vagal denervation. Read More

    Radiofrequency catheter ablation of left-sided accessory pathways in children using a new fluoroscopy integrated 3D-mapping system.
    Europace 2017 Feb 15. Epub 2017 Feb 15.
    Pediatric Cardiology and Cardiac Arrhythmia-Syncope Unit, Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital and Research Institute, Piazza Sant'Onofrio 4, Rome 00165, Italy.

    Accuracy of claims-based algorithms for epilepsy research: Revealing the unseen performance of claims-based studies.
    Epilepsia 2017 Feb 15. Epub 2017 Feb 15.
    Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.
    Objective: To evaluate published algorithms for the identification of epilepsy cases in medical claims data using a unique linked dataset with both clinical and claims data.

    Methods: Using data from a large, regional health delivery system, we identified all patients contributing biologic samples to the health system's Biobank (n = 36K). We identified all subjects with at least one diagnosis potentially consistent with epilepsy, for example, epilepsy, convulsions, syncope, or collapse, between 2014 and 2015, or who were seen at the epilepsy clinic (n = 1,217), plus a random sample of subjects with neither claims nor clinic visits (n = 435); we then performed a medical chart review in a random subsample of 1,377 to assess the epilepsy diagnosis status. Read More

    Serial Changes in Pulmonary Hemodynamics During Pregnancy: A Non-Invasive Study Using Doppler Echocardiography.
    Cardiol Res 2016 Feb 20;7(1):25-31. Epub 2016 Feb 20.
    Department of Medicine, LLRM Medical College, Meerut, UP, India.
    Background: This study aimed to describe the pulmonary hemodynamic changes during the course of pregnancy and to observe any significant effects on symptomatology and outcome of pregnancy due to these changes.

    Methods: A total of 75 patients were recruited for the study, 60 pregnant women from first trimester to third trimester and 6 weeks of puerperium for the study group and 15 non-pregnant patients. All the subjects were interrogated about their complaints like excessive cough, exertional dyspnea, palpitations, orthopnea, syncope, exertional chest pain and lower extremity edema along with their duration. Read More

    Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT Syndrome.
    Circ Cardiovasc Genet 2017 Jan;10(1)
    From the Division of Medical Sciences, University of Victoria, BC, Canada (L.A.S., L.C., X.X., L.T.A.); University of British Columbia Island Medical Program, Victoria, BC, Canada (L.A.S., L.T.A.); Department of Medical Genetics (S.A., S.M., L.T.A.), Division of Cardiology (C.K.), and Division of Cardiology, Department of Pediatrics, BC Children's Hospital (S.S., E.S.), University of British Columbia, Vancouver, BC, Canada; Division of Cardiovascular Medicine, Department of Internal Medicine, Dorothy M. Davis Heart and Lung Research Institute (N.P.M., P.J.L., C.F.K., P.J.M.) and Department of Physiology and Cell Biology (N.P.M., P.J.L., C.F.K., P.J.M.), The Ohio State University Wexner Medical Center, Columbus, OH; Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China (C.W., M.Z.); and Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Western University, London, ON, Canada (J.D.R.).
    Background: Long QT syndrome confers susceptibility to ventricular arrhythmia, predisposing to syncope, seizures, and sudden death. While rare globally, long QT syndrome is ≈15× more common in First Nations of Northern British Columbia largely because of a known mutation in KCNQ1. However, 2 large multigenerational families were affected, but negative for the known mutation. Read More

    Cor triatriatum sinistrum: presentation of syncope and atrial tachycardia.
    BMJ Case Rep 2017 Feb 14;2017. Epub 2017 Feb 14.
    Papworth Hospital NHS Foundation Trust, Cambridge, UK.
    We present a rather unusual cause for syncope associated with atrial tachycardia. A man aged 39 years presented with an episode of syncope and narrow complex tachycardia. Further investigations, including transoesophageal echocardiography, identified cor triatriatum sinistrum (CTS), a rare congenital abnormality characterised by the atrium being divided by a fibrous membrane. Read More

    Long-Term Continuous Ambulatory ECG Monitors and External Cardiac Loop Recorders for Cardiac Arrhythmia: A Health Technology Assessment.
    • Authors:
    Ont Health Technol Assess Ser 2017 31;17(1):1-56. Epub 2017 Jan 31.
    Background: Ambulatory electrocardiography (ECG) monitors are often used to detect cardiac arrhythmia. For patients with symptoms, an external cardiac loop recorder will often be recommended. The improved recording capacity of newer Holter monitors and similar devices, collectively known as longterm continuous ambulatory ECG monitors, suggests that they will perform just as well as, or better than, external loop recorders. Read More

    Potential Deaths Averted and Serious Adverse Events Incurred from Adoption of the SPRINT Intensive Blood Pressure Regimen in the U.S.: Projections from NHANES.
    Circulation 2017 Feb 13. Epub 2017 Feb 13.
    Department of Public Health Sciences, Loyola Medical Center, Maywood, IL.
    Background -The Systolic Blood Pressure Intervention Trial (SPRINT) demonstrated a 27% reduction in all-cause mortality with a systolic blood-pressure (SBP) goal of <120 mmHg versus <140 mmHg among U.S. adults at high cardiovascular disease (CVD) risk but without diabetes, stroke, or heart failure. Read More

    Evaluation of the first seizure patient: Key points in the history and physical examination.
    Seizure 2016 Dec 8. Epub 2016 Dec 8.
    Division of Neurology, Department of Medicine, University of Alberta, 7th Floor Clinical Sciences Building, 11350 83 Avenue NW, Edmonton, Alberta T6G 2G3, Canada.
    Purpose: This review will present the history and physical examination as the launching point of the first seizure evaluation, from the initial characterization of the event, to the exclusion of alternative diagnoses, and then to the determination of specific acute or remote causes. Clinical features that may distinguish seizures from alternative diagnoses are discussed in detail, followed by a discussion of acute and remote first seizure etiologies.

    Methods: This review article is based on a discretionary selection of English language articles retrieved by a literature search in the PubMed database, and the authors' clinical experience. Read More

    Vaccine adverse events in a safety net healthcare system and a managed care organization.
    Vaccine 2017 Mar 6;35(9):1335-1340. Epub 2017 Feb 6.
    Institute for Health Research, Kaiser Permanente Colorado, United States; Ambulatory Care Services, Denver Health, United States; Pediatrics and Epidemiology, University of Colorado, United States.
    Background: The Institute of Medicine, in a 2013 report, recommended that the Vaccine Safety Datalink (VSD) expand collaborations to include more diversity in the study population. Kaiser Permanente Colorado (KPCO), an established VSD site, partnered with Denver Health (DH), an integrated safety net healthcare system, to demonstrate the feasibility of integrating DH data within the VSD. Prior to incorporating the data, we examined the identification of specific vaccine associated adverse events (VAEs) in these two distinct healthcare systems. Read More

    Composite Lymphoma: Opposite Ends of Spectrum Meet.
    J Clin Med Res 2017 Mar 25;9(3):213-215. Epub 2017 Jan 25.
    St. John Hospital and Medical Center, Detroit, MI, USA.
    An 18-year-old African-American female presented with an episode of syncope. Initial investigations revealed large lung mass with invasion into right atrium along with lesions in kidneys and liver. Patient also developed superior vena cava syndrome due to lung mass. Read More

    Application of pediatric appropriate use criteria for initial outpatient evaluation of syncope.
    Echocardiography 2017 Feb 8. Epub 2017 Feb 8.
    Emory University School of Medicine, Atlanta, GA, USA.
    Background: Syncope is a common reason for outpatient transthoracic echocardiography (TTE). We studied the applicability of pediatric appropriate use criteria (AUC) on initial outpatient evaluation of children (≤18 years) with syncope.

    Methods: Data were obtained before (Phase I, April-September 2014) and after (Phase II, January-April 2015) the release of the AUC document from six participating pediatric cardiology centers. Read More

    Night syncope: a case report.
    Clin Case Rep 2017 Feb 26;5(2):81-84. Epub 2016 Dec 26.
    Cardiology Clinique Universitaire UCL Mont-Godinne Rue Dr G Therasse 1 Yvoir 5530 Belgium.
    "Idiopathic" ventricular fibrillations are rare and are estimated between 5% and 10% of survivors of hospital cardiac arrest, for at least some of them have as origin, a trigger in the Purkinje fibers. Interventional therapy could be an effective, long-lasting solution for these recurrent malignant arrhythmias and should be considered. Read More

    Prevalence of epilepsy in 74,949 school children in Khartoum State, Sudan.
    Paediatr Int Child Health 2017 Feb 6:1-5. Epub 2017 Feb 6.
    f Division of Pediatric Neurology, Department of Pediatrics , College of Medicine, King Saud University , Riyadh , Saudi Arabia.
    Background: Data on childhood epilepsy in Sudan are scarce and the only published study on its prevalence was published in 1983. This study aimed to determine the current prevalence of epilepsy in school children in Khartoum State.

    Methods: This is an analytical population-based, cross-sectional study conducted in Khartoum State, Sudan. Read More

    The Cardiovascular System after Exercise.
    J Appl Physiol (1985) 2017 Feb 2:jap.00802.2016. Epub 2017 Feb 2.
    University of Oregon
    Recovery from exercise refers to the time period between the end of a bout of exercise and the subsequent return to a resting or recovered state. It also refers to specific physiological processes or states, occurring after exercise, which are distinct from the physiology of either the exercising or the resting states. In this context, recovery of the cardiovascular system after exercise occurs across a period of minutes to hours, during which many characteristics of the system, even how it is controlled, are changing over time. Read More

    Implantation of VVI pacemaker in a patient with dextrocardia, persistent left superior vena cava, and sick sinus syndrome: A case report.
    Medicine (Baltimore) 2017 Feb;96(5):e6028
    aDepartment of Cardiology, China-Japan Union Hospital, Jilin University bDepartment of Gynecology and Obstetrics cDepartment of Pediatric, the First Hospital of Jilin University, Changchun, Jilin Province, china.
    Background: Dextrocardia, or right-lying heart, is an uncommon congenital heart disease in which the apex of the heart is located on the right side of chest. Persistent left superior vena cava (PLSVA) is a rare venous anomaly that is often associated with the abnormalities of cardiac transduction system. A case with combination of dextrocardia, persistent left superior vena cava, and sick sinus syndrome has not been reported. Read More

    Syncope: Outcomes and Conditions Associated with Hospitalization.
    Am J Med 2017 Jan 29. Epub 2017 Jan 29.
    University of Iowa Hospitals and Clinics. Iowa City, IA.
    Purpose: Syncope is a perplexing problem for which hospital admission and readmission are contemplated but outcomes remain uncertain. Our purpose was to determine the incidence of admissions and readmissions for syncope and compare associated conditions, in-hospital outcomes and resource utilization.

    Methods: The 2005-2011 California Statewide Inpatient Database was utilized. Read More

    Sudden Collapse of a Preschool-Aged Child on the Playground.
    Pediatr Emerg Care 2017 Feb;33(2):116-119
    From the Divisions of *Emergency Medicine, †Pharmacy, and ‡Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
    Purpose: Primary cardiac events are rare in children. There is little information in the literature regarding the most appropriate emergency department (ED) management of this type of pediatric patient, especially with regard to medication use.

    Summary: This case highlights the pediatric ED evaluation and treatment of sudden collapse in a child with an ultimate diagnosis of hypertrophic cardiomyopathy. Read More

    An Overview of Pharmacotherapy in Hypertrophic Cardiomyopathy: Current Speculations and Clinical Perspectives.
    Rev Cardiovasc Med 2016 ;17(3-4):115-123
    Cardiomyopathies Center, First Cardiology Department, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
    Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease. Its clinical course is variable, ranging from a benign asymptomatic or mildly symptomatic course throughout life, to severe symptoms (dyspnea, angina, palpitations) or cardiovascular events (syncope and thromboembolism). Sudden cardiac death (SCD) remains the most striking manifestation of the disease, affecting a minority of patients. Read More

    Hypertrophic obstructive cardiomyopathy with multiple coronary arteries to right ventricular microfistulas: a case report and review of the literature.
    J Med Case Rep 2017 Jan 31;11(1):24. Epub 2017 Jan 31.
    Department of Cardiology, Swai Man Singh Medical College, Jaipur, Rajasthan, India.
    Background: Coronary artery microfistulas are a rare anomaly; their association with hypertrophic cardiomyopathy is even rarer and can lead to serious cardiac complications owing to coronary steal phenomena such as angina pectoris, myocardial infarction, congestive heart failure, ventricular and supraventricular arrhythmias, syncope, and sudden death.

    Case Presentation: A 32-year-old Indian woman presented to our institute with severe angina on exertion and multiple episodes of pre-syncope. Echocardiography revealed hypertrophic obstructive cardiomyopathy. Read More

    Wide QRS in a 2-month infant associated with recurrent ventricular tachycardia: A case of Brugada-like syndrome.
    Ann Cardiol Angeiol (Paris) 2017 Jan 27. Epub 2017 Jan 27.
    Cardiology B department, Fattouma Bourguiba University Hospital and University of Monastir, avenue du 1er Juin, 5000 Monastir, Tunisia.
    We report the case of a 2-month old infant who experienced recurrent sustained ventricular tachycardia (VT) in a structurally normal heart. Resting electrocardiogram (ECG) showed wide QRS with a complete right bundle branch bloc (RBBB) morphology. There was no family history of syncope or sudden death, but the ECGs of the father and the brother showed incomplete RBBB with negative T waves on V1 lead. Read More

    Treating an Adolescent with Long QT Syndrome for Bipolar Disorder: A Case Presentation.
    Psychopharmacol Bull 2017 Jan;47(1):33-39
    Drs. Önen, Kutlu, Erkuran, MD, Dr. Behcet Uz Children's Hospital Department of Child and Adolescent Psychiatry, Izmir, Turkey.
    Objectives: Long QT syndrome (LQTS) is described as the development of sudden syncope attacks or death as a result of ventricular tachycardia (VT) episodes that might be observed as elongated QT interval in electrocardiography (ECG). Implantable Cardioverter Defibrillator (ICD) is recommended as first-line treatment for the condition in guidelines. We aimed to present an adolescent recently diagnosed with Bipolar Disorder (BD) who had LQTS that was treated with ICD, discussing her follow up and treatment along with relevant literature. Read More

    Geriatric Syncope and Cardiovascular Risk in the Emergency Department.
    J Emerg Med 2017 Jan 25. Epub 2017 Jan 25.
    Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
    Background: Syncope is a transient loss of consciousness that is caused by a brief loss in generalized cerebral blood flow.

    Objective: This article reviews the background, epidemiology, etiologies, evaluation, and disposition considerations of geriatric patients with syncope, with a focus on cardiovascular risk.

    Discussion: Although syncope is one of the most common symptoms in elderly patients presenting to the emergency department, syncope causes in geriatric patients can present differently than in younger populations, and the underlying etiology is often challenging to discern. Read More

    Right ventricular dysfunction in acute pulmonary embolism: NT-proBNP vs troponin T.
    Med Clin (Barc) 2017 Jan 25. Epub 2017 Jan 25.
    Servicio de Medicina Interna, Hospital Universitario Virgen de la Arrixaca, Murcia, España; Universidad Católica San Antonio, Murcia, España.
    Background And Objective: Dysfunction of the right ventricle (RV) is a parameter of severity in acute pulmonary embolism (PE). Echocardiographic assessment is not always possible in accident and emergency, hence the need to predict the presence of RV dysfunction using easily measurable parameters. To analyse the value of NT-proBNP and troponin T as markers of RV dysfunction in patients with acute PE. Read More

    Nationwide Trends in Syncope Hospitalizations and Outcomes From 2004 to 2014.
    Can J Cardiol 2016 Nov 11. Epub 2016 Nov 11.
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada; Canadian VIGOUR Centre, University of Alberta, Edmonton, Alberta, Canada.
    Background: We examined the prevalence, comorbidity burden, and outcomes of patients who presented to acute care hospitals with a primary diagnosis of syncope over a 10-year period in Canada.

    Methods: The Canadian Institute for Health Information Discharge Abstract Database (which contains detailed health information from all Canadian provinces and territories except Quebec) was used to identify hospitalizations of patients with a primary diagnosis of syncope (International Classification of Diseases-10th Revision code R55) 20 years of age or older in Canada from 2004 to 2014. Annual age- and sex-standardized hospital discharge rates were calculated. Read More

    [Loss of capture by myocardial ischemia: A case report].
    Ann Cardiol Angeiol (Paris) 2017 Jan 24. Epub 2017 Jan 24.
    Centre national hospitalier universitaire Hubert Koutoukou Maga de Cotonou, Cotonou, Bénin. Electronic address:
    We report the case of a patient with pacemaker who presented chest pain during exercise followed by fainting. He has a history of arterial hypertension and diabetes. The initial examination was normal; the ventricular stimulation threshold was 1. Read More

    [The SPRINT study - the outcomes of the most important study over the recent period focused on hypertension].
    Vnitr Lek 2016 ;62(11):933-937
    When treating systolic hypertension we do not know the optimum blood pressure which leads to the reduction of cardiovascular events and cardiovascular and total mortality. The results of the ACCORD study, when comparing intensive treatment of systolic blood pressure < 120 mm Hg and standard treatment < 140 mm Hg, did not lead to affecting the primary target for patients with diabetes mellitus. In the autumn last year the SPRINT study was presented and published, showing favourable impact on the combined primary target, which involved myocardial infarction, other acute coronary syndromes, stroke, heart failure or death from cardiovascular causes during intensive treatment of systolic blood pressure, i. Read More

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