Search Our Scientific Publications & Authors

Arch Bronconeumol 2022 Apr 20;58(4):354-355. Epub 2022 Jan 20.

Servicio de Neumología, Hospital Universitario Virgen Macarena, Sevilla, España.

Br J Radiol 2022 Jun 22;95(1134):20210957. Epub 2022 Feb 22.

Institute of Nuclear Medicine, University College London (UCL), London, UK.

Objective: To assess the prognostic performance of two quantitative CT (qCT) techniques in idiopathic pulmonary fibrosis (IPF) compared to established clinical measures of disease severity (GAP index).

Methods: Retrospective analysis of high-resolution CT scans for 59 patients (age 70.5 ± 8. Read More

Respir Med Case Rep 2022 3;36:101569. Epub 2022 Jan 3.

University of Oklahoma Health and Sciences Center, Department of Pulmonary, Critical Care and Sleep Medicine, 800 Stanton L Young Boulevard, AAT 8400, Oklahoma City, OK, 73104, USA.

Swyer-James syndrome (SJS) is a rare lung condition characterized by abnormal lung growth secondary to childhood post-infectious bronchiolitis obliterans. Usually, one lung is affected more than the other leading to asymmetrical lungs with one lung being significantly smaller. The disease can lead to pulmonary obstructive airflow physiology, bronchiectasis, and fibrosis. Read More

Eur Respir J 2021 Dec 23. Epub 2021 Dec 23.

Toronto Lung Transplant Program, Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada.

Background: Chronic lung allograft dysfunction (CLAD) is the principal cause of graft failure in lung transplant recipients and prognosis depends on CLAD phenotype. We used machine learning computed tomography (CT) lung texture analysis tool at CLAD diagnosis for phenotyping and prognostication compared to radiologists' scoring.

Methods: This retrospective study included all adult first double-lung transplant patients (01/2010-12/2015) with CLAD (censored 12/2019) and inspiratory CT near CLAD diagnosis. Read More

Klin Padiatr 2022 Mar 15;234(2):113-115. Epub 2021 Dec 15.

Center for Pediatrics - Department of General Pediatrics, Adolescent Medicine and Neonatology, Medical Center-University of Freiburg, Freiburg, Germany.

Pediatr Radiol 2022 Apr 30;52(4):622-636. Epub 2021 Oct 30.

Division of Pediatric Radiology, Department of Radiology, NYU Grossman School of Medicine, 550 First Ave., New York, NY, 10016, USA.

Congenital lung malformations represent a spectrum of abnormalities that can overlap in imaging appearance and frequently coexist in the same child. Imaging diagnosis in the neonatal period can be challenging; however, the recognition of several archetypal radiographic patterns can aid in narrowing the differential diagnosis. Major radiographic archetypes include (1) hyperlucent lung, (2) pulmonary cysts, (3) focal opacity and (4) normal radiograph. Read More

BMJ Case Rep 2021 Sep 13;14(9). Epub 2021 Sep 13.

Radiology, Centro Hospitalar de Entre o Douro e Vouga EPE, Santa Maria da Feira, Portugal.

Asian J Surg 2021 Jun 20;44(6):913-914. Epub 2021 Apr 20.

Department of Surgery, Show Chwan Memorial Hospital, Changhua, 500, Taiwan. Electronic address:

Radiol Cardiothorac Imaging 2020 Jun 18;2(3):e190246. Epub 2020 Jun 18.

Instituto de Radiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Rua Dr. Ovídio Pires de Campos, 75-Cerqueira César, São Paulo, SP, CEP 05403-010, Brazil.

Sci Rep 2021 03 22;11(1):6577. Epub 2021 Mar 22.

Cardiovascular and Pulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health, Building 10, Room B1D416, 10 Center Drive, Bethesda, MD, 20814, USA.

In this work, we sought to delineate the prevalence of cardiothoracic imaging findings of Proteus syndrome in a large cohort at our institution. Of 53 individuals with a confirmed diagnosis of Proteus syndrome at our institution from 10/2001 to 10/2019, 38 individuals (men, n = 23; average age = 24 years) underwent cardiothoracic imaging (routine chest CT, CT pulmonary angiography and/or cardiac MRI). All studies were retrospectively and independently reviewed by two fellowship-trained cardiothoracic readers. Read More

Aerosp Med Hum Perform 2021 Apr;92(4):281-285

Swyer-James-MacLeod syndrome (SJMS) is a specific form of bronchiolitis obliterans that occurs rarely, but represents recognized sequelae of common pediatric respiratory illness, and presents as unilateral hyperlucency on chest imaging. This case study describes such an incidental radiographic finding identified during the assessment of chest wall discomfort in a military pilot. A 35-yr-old military pilot presented to his flight surgeon with vague intermittent chest discomfort. Read More

Radiol Case Rep 2021 May 8;16(5):1133-1137. Epub 2021 Mar 8.

Department of Surgery, AUSL Piacenza, Via Taverna 49, 29121 Piacenza, Italy.

Swyer-James-MacLeod Syndrome (SJMS) is an uncommon, emphysematous disease characterized by obliteration of the small bronchioles, hypoplasia/or absence of pulmonary artery and peripheral vascular bed. It is most commonly diagnosed in childhood. Patients are often asymptomatic or they could suffer from symptoms of recurrent pulmonary infections. Read More

Cureus 2021 Jan 10;13(1):e12601. Epub 2021 Jan 10.

Pulmonology Department, Laiko General Hospital, Athens, GRC.

Swyer-James-Macleod syndrome is an infrequent clinical condition characterized by unilateral hyperlucent lung as a complication following infectious bronchiolitis obliterans, typically diagnosed during childhood. However, in some patients, the diagnosis may be confirmed in adulthood. The syndrome can be misdiagnosed with other lung disorders such as asthma, pulmonary embolism, and pneumothorax, leading to inappropriate management and worse outcome. Read More

Am J Med Sci 2021 02 28;361(2):e13-e14. Epub 2020 Jul 28.

Division of Pulmonary and Critical Care Medicine, Ozarks Medical Center, 1100 Kentucky Avenue, West Plains, MO 65775, United States. Electronic address:

S D Med 2019 Nov;72(11):518-520

Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska Medical Center, Omaha, Nebraska.

Swyer-James-Macleod syndrome is a rare radiologic entity with radiolucent lung fields which could include the entire lung, a lobe or a subsegment. The pathogenesis is unclear but is thought to be related to childhood pulmonary viral and non-viral infections with subsequent vascular and alveolar distortion. It usually presents incidentally in asymptomatic patients on imaging, but could present with recurrent pulmonary infections, shortness of breath, cough, hemoptysis or bronchiectasis. Read More

BMJ Case Rep 2020 Jan 8;13(1). Epub 2020 Jan 8.

Department of Respiratory Medicine, Royal Liverpool and Broadgreen Hospitals NHS Trust, Liverpool, UK.

This case describes a female patient who presented with an acute on chronic deterioration in respiratory symptoms, on a background of chronic obstructive pulmonary disease and heavy cigarette smoking. Chest radiograph demonstrated long-standing hyperlucency of the right lower lobe, with further imaging later confirming the rare combination of Swyer-James-MacLeod syndrome and multiple pulmonary arteriovenous malformations within the affected lung. Read More

Chest 2020 01 26;157(1):119-141. Epub 2019 Jul 26.

Pulmonary, Critical Care & Sleep Medicine, Lenox Hill Hospital, New York, NY; Medicine and Radiology, Barbara and Donald Zuckerberg School of Medicine at Hofstra/Northwell, New York, NY. Electronic address:

Areas of diminished lung density are frequently identified both on routine chest radiographs and chest CT examinations. Colloquially referred to as hyperlucent foci of lung, a broad range of underlying pathophysiologic mechanisms and differential diagnoses account for these changes. Despite this, the spectrum of etiologies can be categorized into underlying parenchymal, airway, and vascular-related entities. Read More

Eur J Nucl Med Mol Imaging 2019 Sep 8;46(10):2023-2031. Epub 2019 Jul 8.

Institute of Nuclear Medicine, UCL(H) and University College London Hospital, 235 Euston Rd, London, NW1 2BU, UK.

Introduction: To investigate the combined performance of quantitative CT (qCT) following a computer algorithm analysis (IMBIO) and F-FDG PET/CT to assess survival in patients with idiopathic pulmonary fibrosis (IPF).

Methods: A total of 113 IPF patients (age 70 ± 9 years) prospectively and consecutively underwent F-FDG PET/CT and high-resolution CT (HRCT) at our institution. During a mean follow-up of 29. Read More

Hawaii J Med Public Health 2019 04;78(4):137-140

Division of Cardiology, Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI.

A 24-year-old female with a history of Swyer-James-MacLeod syndrome presented with acute onset of pleuritic chest pain and was initially diagnosed with acute pericarditis. The 12-lead electrocardiogram demonstrated typical diffuse ST-segment elevation and PR-segment depression. Symptoms resolved rapidly with anti-inflammatory therapy consisting of ibuprofen and colchicine. Read More

Ann Card Anaesth 2018 Oct-Dec;21(4):440-441

Department of Cardiothoracic Vascular Surgery, SGPGIMS, Lucknow, Uttar Pradesh, India.

We report an interesting case of bulla right lung, incidently found during CABG surgery. Read More

J Bras Pneumol 2018 May-Jun;44(3):182

. Universidade Federal do Rio de Janeiro, Rio de Janeiro (RJ) Brasil.

Pediatr Int 2018 Jul 20;60(7):669-670. Epub 2018 Jun 20.

Department of Pediatric Radiology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.

Ann Acad Med Singap 2018 Jan;47(1):48-50

Department of Respiratory and Critical Care Medicine, Khoo Teck Puat Hospital, Singapore.

Am J Emerg Med 2018 May 9;36(5):909.e5-909.e6. Epub 2018 Feb 9.

Bozok University, Department of Emergency Medicine, Yozgat, Turkey.

Unilateral hyperlucent lung was firstly described by Swyer and James 1950s. After that, some patients with same disease were detected by Macleod . Then this syndrome was named as Swyer- James-Macleod syndrome (SJMS), and this syndrome includes a smaller or normal sized unilateral hyperlucent lung. Read More

Tuberk Toraks 2017 09;65(3):258-259

Division of Respiratory Medicine, Mito Medical Center, Tsukuba University, Mito, Japan.

Am J Respir Crit Care Med 2018 01;197(1):130-131

1 Department of Respiratory Medicine and Infectious Disease.

Zhongguo Dang Dai Er Ke Za Zhi 2017 Oct;19(10):1056-1060

Department of Respiratory Diseases, Children's Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorders/China International Science and Technology Cooperation Base of Child Development and Critical Disorders/Chongqing Engineering Research Center of Stem Cell Therapy, Chongqing 400014, China.

Objective: To investigate the clinical features of readmitted children with bronchopulmonary dysplasia (BPD) in the first 2 years of life.

Methods: A retrospective analysis was performed for the clinical data of 242 children with BPD who were readmitted due to recurrent lower respiratory tract infection (LRTI) in the first 2 years of life.

Results: Among all the 242 children with BPD, 115(47. Read More

Respirol Case Rep 2017 07 17;5(4):e00236. Epub 2017 Apr 17.

Department of Internal Medicine Toyama Prefectural Central Hospital Toyama Japan.

Swyer-James-MacLeod syndrome (SJMS) is an uncommon obliterative lung disease that is radiologically characterized by hyperlucency of a part of or the entire lung. A 33-year-old man presented to our hospital for chest tightness. A chest X-ray revealed unilateral hyperlucency of left lower lung, and contrast-enhanced computed tomography (CT) of the chest disclosed a hyperlucent left lung without vascularity. Read More

J Pediatr Surg 2017 Sep 31;52(9):1442-1445. Epub 2017 Jan 31.

Division of Pediatric General, Thoracic and Fetal Surgery, Department of Surgery, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA. Electronic address:

Background: Only a few isolated cases in the literature exist to guide management of bilateral congenital lobar emphysema (CLE). Here, we review our experience in infants with bilateral CLE.

Methods: A case series of all infants presenting with bilateral CLE from 2014 to 2015 in a single institution. Read More

J Investig Allergol Clin Immunol 2016;26(6):390-392

Department of Translational Medical Sciences, Unit of Immunology, Federico II University, Naples, Italy.