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Clinics (Sao Paulo) 2022 Jun 24;77:100071. Epub 2022 Jun 24.

Divisão de Fonoaudiologia do Instituto Central do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address:

Objective: To investigate the clinical and swallowing indicators related to a successful decannulation process during the hospital stay.

Methods: A retrospective cohort clinical study. The study sample comprised a heterogeneous patient population who had submitted to a tracheostomy procedure in a tertiary hospital. Read More

Front Vet Sci 2022 9;9:889331. Epub 2022 Jun 9.

Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.

Swallowing impairment is a highly prevalent and clinically significant problem affecting people and dogs. There are myriad causes of swallowing impairment of which gastroesophageal reflux is the most common in both species. Similarities in anatomy and physiology between humans and canines results in analogous swallowing disorders including cricopharyngeus muscle achalasia, esophageal achalasia, hiatal herniation, and gastroesophageal reflux with secondary esophagitis and esophageal dysmotility. Read More

Sensors (Basel) 2022 Jun 15;22(12). Epub 2022 Jun 15.

Centro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, 46022 Valencia, Spain.

Swallowing is a complex sequence of highly regulated and coordinated skeletal and smooth muscle activity. Previous studies have attempted to determine the temporal relationship between the muscles to establish the activation sequence pattern, assessing functional muscle coordination with cross-correlation or coherence, which is seriously impaired by volume conduction. In the present work, we used conditional Granger causality from surface electromyography signals to analyse the directed functional coordination between different swallowing muscles in both healthy and dysphagic subjects ingesting saliva, water, and yoghurt boluses. Read More

Nutrients 2022 Jun 16;14(12). Epub 2022 Jun 16.

Food Lab, Department of Pharmacy, University of Naples "Federico II", Via Domenico Montesano 49, 80131 Naples, Italy.

Gastroesophageal Reflux Disease (GERD) is multifactorial pathogenesis characterized by the abnormal reflux of stomach contents into the esophagus. Symptoms are worse after the ingestion of certain foods, such as coffee. Hence, a randomized pilot study conducted on 40 Italian subjects was assessed to verify the effect of standard (SC) and dewaxed coffee (DC) consumption on gastroesophageal reflux symptoms and quality of life in patients with gastrointestinal diseases. Read More

Nutrients 2022 Jun 16;14(12). Epub 2022 Jun 16.

Gastrointestinal Physiology Laboratory, Hospital de Mataró, Universitat Autònoma de Barcelona, 08304 Barcelona, Spain.

Background: The effect of oropharyngeal dysphagia (OD) and thickened fluid (TF) therapy on hydration status has not been well defined in the literature. We aimed to assess the hydration status in patients with OD and the effect TF therapy has on it.

Methods: Two literature reviews following PRISMA methodology (each one including a systematic and a scoping review) were performed: (R1) hydration status in adult patients with OD; (R2) effect of TF therapy on fluid intake and dehydration. Read More

BMC Pediatr 2022 Jun 23;22(1):360. Epub 2022 Jun 23.

Institute of Clinical Physiology, National Research Council of Italy (CNR), Pisa, Italy.

Background: Children with neurological impairment may have dysphagia and/or gastro-esophageal reflux disease (GERD), which predispose to complications affecting the airways, increasing risk for aspiration-induced acute and chronic lung disease, or secondarily malnutrition, further neurodevelopmental disturbances, stressful interactions with their caregivers and chronic pain. Only multidisciplinary clinical feeding evaluation and empirical trials are applied to provide support to the management of feeding difficulties related to dysphagia or GERD, but no standardized feeding or behavioral measure exists at any age to assess aspiration risk and support the indication to perform a videofluoroscopic swallowing study (VFSS) or a fibre-optic endoscopic examination of swallowing (FEES), in particular in newborns and infants with neurological impairments. Lung ultrasound (LUS) has been proposed as a non-invasive, radiation-free tool for the diagnosis of pulmonary conditions in infants, with high sensitivity and specificity. Read More

BMC Gastroenterol 2022 Jun 23;22(1):307. Epub 2022 Jun 23.

Department of Gastroenterology, First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, Jiangsu Province, China.

Background: Hypercontractile esophagus is a rare hypercontractile esophageal motility disorder. The etiology of hypercontractile esophagus is unknown but an association between acid reflux and hypercontractile esophagus has been suggested. We present the first report on the use of potassium-competitive acid blockers in the treatment of hypercontractile esophagus. Read More

Acta Clin Croat 2021 Dec;60(4):703-710

1Gastroenterology Department, Iasi Regional Institute of Oncology, Iasi, Romania; 2Grigore T. Popa University of Medicine and Pharmacy; Faculty of Medicine, Surgery Department 2, Iasi Regional Institute of Oncology, Iasi, Romania; 3Iasi University of Medicine and Pharmacy, Faculty of Medicine, Anesthesiology and Intensive Care Department, Iasi Regional Institute of Oncology, Iasi, Romania.

The aim of the study was to outline technical difficulties and procedural complications of using partially covered esophageal self-expandable metal stents (SEMSs) in malignant esophageal respiratory fistulas (ERFs) as a palliative treatment option. In this study, 150 patients with malignant dysphagia underwent treatment with SEMSs. A total of 36 ERFs were detected through endoscopic or clinical assessment. Read More

BMC Neurol 2022 Jun 22;22(1):231. Epub 2022 Jun 22.

Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.

Background: Stroke is the main cause of oropharyngeal neurogenic dysphagia. Electrostimulation has been used as a therapeutic tool in these cases. However, there are few studies that prove its effectiveness. Read More

BMJ Open 2022 Jun 22;12(6):e058852. Epub 2022 Jun 22.

Department of Otolaryngology, Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong Provincial ENT Hospital Affiliated to Shandong University, Jinan, Shandong, China.

Objectives: This study aimed to investigate the status of the current knowledge about laryngopharyngeal reflux disease (LPRD) among Chinese otolaryngologists.

Design: Multi-centre cross-sectional survey.

Setting: 220 medical centres in different regions of China. Read More

Emerg Med J 2022 Jul;39(7):553-566

Emergency Medicine, University of California San Francisco, San Francisco, California, USA.

MMW Fortschr Med 2022 Jun;164(12):28-29

Medzinische Klinik 2, Diakonissenkrankenhaus Mannheim, Speyerer Str. 91-93, 68163, Mannheim, Deutschland.

Arq Bras Cir Dig 2022 17;35:e1657. Epub 2022 Jun 17.

Department of Surgery, Hospital "Dr. José J Aguirre", Faculty of Medicine, University of Chile, Santos Dumont 999, Santiago, Chile.

Aim: Laparoscopic Roux-en-Y gastric bypass (LGB) is the recommended procedure for morbidly obese patients with gastroesophageal reflux disease (GERD). However, there have been reported gastroesophageal reflux symptoms or esophagitis after LGB. Few functional esophageal studies have been reported to date. Read More

Arq Bras Cir Dig 2022 17;35:e1650. Epub 2022 Jun 17.

Federal University of Rio de Janeiro, Digestive Motility Laboratory - Gastroenterology Division of HUCFF-UFRJ, Rio de Janeiro, RJ, Brazil.

Aim: Dysphagia can lead to aspiration pneumonia, impacting the nutritional status and quality of life of the patient. The videofluoroscopy is highlighted for allowing both a real-time evaluation and the recording of the images for later review and analysis. This study aimed to describe the characteristics of the population referred for videofluoroscopy and its value as an investigation method. Read More

Codas 2022 17;34(5):e20200214. Epub 2022 Jun 17.

Universidade Federal do Rio Grande do Sul - UFRGS - Porto Alegre (RS), Brasil.

Purpose: To identify the factors associated with frailty in patients with neurodegenerative diseases.

Methods: Cross-sectional study, whose sample consisted of 150 patients diagnosed with neurodegenerative diseases seen at a speech-language therapy clinic in a reference hospital in southern Brazil. A secondary exploratory analysis of the medical records of patients treated at this clinic between April 2016 and May 2019 was performed. Read More

J Taibah Univ Med Sci 2022 Jun 14;17(3):362-368. Epub 2022 Jan 14.

Clinic of Social and Family Medicine, Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.

Objectives: Dysphagia is defined as any feeding or swallowing dysfunction at one or more stages of digestion. This study aims to investigate the prevalence of dysphagia symptoms in children and adolescents with neurological disorders and its relationship with the specific characteristics of the subjects.

Methods: Using data from general hospital/paediatric department visits in Heraklion, Crete, Greece, a cross-sectional study design was implemented over a seven-month period (2017-18), and a total of 268 children and adolescents were recruited. Read More

Pan Afr Med J 2022 18;41:225. Epub 2022 Mar 18.

Gastroenterology Department, Mohamed Tahar Maamouri Hospital, Nabeul, Tunisia.

Esophageal tuberculosis is a rare cause of infectious esophagitis, even in countries with endemic tuberculosis. This impairment is often secondary. We report a case of secondary esophageal tuberculosis in an immunocompetent patient, clinically revealed by dysphagia. Read More

J Nutr Health Aging 2022 ;26(6):590-597

Yoshihiro Yoshimura, Kumamoto Rehabilitation Hospital, Kikuchi, Kumamoto, Japan,

Objectives: To investigate the predictive value of the BIA-derived phase angle with respect to the functional prognosis and baseline sarcopenia in patients undergoing post-stroke rehabilitation.

Design: Retrospective cohort study.

Setting And Participants: Overall, 577 Japanese patients admitted to a post-acute care hospital from 2016 to 2020 were recruited. Read More

Jpn J Nurs Sci 2022 Jun 18:e12496. Epub 2022 Jun 18.

Department of Speech and Hearing Sciences, International University of Health and Welfare, Narita, Japan.

Aim: This clinical practice guideline aims to provide and recommend methods of assessing aspiration and pharyngeal residue during eating and swallowing and methods of selecting and implementing nursing care for adults to prevent the development of aspiration pneumonia through early and appropriate management of oropharyngeal dysphagia.

Methods: In April 2018, the Japan Academy of Nursing Science established the Supervisory Committee in Nursing Care Development/Standardization Committee to develop clinical practice guidelines for aspiration and pharyngeal residual assessment during eating and swallowing for nursing care. This clinical practice guideline was developed according to the Minds Manual for Guideline Development 2017, with the aim of providing a specific pathway for nurses to determine the policy for selecting management for oropharyngeal dysphagia based on research evidence and multifaceted factors including the balance of benefits and harms and patients' values. Read More

PLoS One 2022 17;17(6):e0270252. Epub 2022 Jun 17.

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

The increasing usage of proton pump inhibitors (PPIs) has been reported worldwide, but information on PPI use in East Asia is inadequate. This study aimed to examine the trends in PPI use in Japan, along with the changes in histamine H2 receptor antagonist (H2RA) use, disease rate of reflux esophagitis, and the prevalence of upper gastrointestinal symptoms. We analyzed 217,712 healthy subjects (127,607 men and 90,105 women; 51. Read More

Dysphagia 2022 Jun 17. Epub 2022 Jun 17.

Communication Disorders and Sciences Program, University of Oregon, Eugene, 97403, USA.

Both chronic obstructive pulmonary disease (COPD) and dysphagia can be complicated by the shared physiological-psychoemotional manifestations of the conditions, such as anxiety and respiratory dysfunction. Despite their shared comorbidities, clinical research and management often focus on the isolated physiological impairments of each condition separately. Crucially, the oral intake experience of individuals with COPD-central for improved quality of life-remains underexplored. Read More

Medicine (Baltimore) 2022 Jun 17;101(24):e29441. Epub 2022 Jun 17.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

Background: : Current guidelines recommend per-oral endoscopic myotomy (POEM) and laparoscopic Heller's myotomy (LHM) as first-line treatment of idiopathic achalasia, but the optimum choice between different endoscopic and surgical modalities remains inconclusive. We conducted a network meta-analysis to compare the efficacy of 8 treatments for idiopathic achalasia.

Materials And Methods: : Three major bibliographic databases were reviewed for enrollment of randomized controlled trials between January 2000 and June 2021. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2022 Jun;36(6):739-744

Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.

Objective: To introduce a new occipitocervical angle parameter, occipito-odontoid angle (O-Da), for predicting dysphagia after occipitocervical fusion (OCF) in patients with C Klippel-Feil syndrome (KFS) and analyze its effectiveness.

Methods: A total of 119 patients met selective criteria between April 2010 and November 2019 were retrospectively included as the study subjects. There were 56 males and 63 females. Read More

PLoS One 2022 16;17(6):e0270107. Epub 2022 Jun 16.

Department of Physiotherapy, Speech-Language and Hearing Science and Occupational Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.

The purpose of this research was to identify risk factors that were independently related to the maintenance of a swallowing dysfunction in patients affected by critical COVID-19. We conducted a prospective observational cohort study of critical patients with COVID-19, who were admitted to a COVID-19 dedicated intensive care unit (ICU) and required prolonged orotracheal intubation (≥48 hours). Demographic and clinical data were collected at ICU admission and/or at hospital discharge or in-hospital death. Read More

PLoS One 2022 16;17(6):e0270096. Epub 2022 Jun 16.

Division of Rheumatology, The First People's Hospital of Lianyungang, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.

Background: Dysphagia is a common yet serious complication in stroke patients. We aimed to conduct a meta-analysis and systematic review to evaluate the risk factors of dysphagia in patients with ischemic stroke, to provide insights to the clinical treatment and nursing care of dysphagia.

Methods: We searched PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI) and Wanfang Database, China Biomedical Literature Database (CBM) for studies on dysphagia in patients with ischemic stroke up to January 31, 2022. Read More

BMJ Open 2022 Jun 15;12(6):e061893. Epub 2022 Jun 15.

Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China

Introduction: Dysphagia is a common functional disorder after stroke. Most patients post-stroke are incapable of oral feeding, which often leads to complications such as malnutrition, aspiration pneumonia and dehydration that seriously affect the quality of life of patients. Oropharyngeal muscle strength training is a major method of swallowing training, and recent studies have focused on healthy adults, elderly persons, and patients with head and neck cancer or neurodegenerative diseases; but there have been few studies on such training in patients with post-stroke dysphagia. Read More

Trials 2022 Jun 13;23(1):490. Epub 2022 Jun 13.

Geriatric Psychiatry Department, Affiliated Brain Hospital of Guangzhou Medical University, 36 MingXin Road, Liwan Distrist, Guangzhou, China.

Background: The high prevalence of dysphagia among Alzheimer's disease (AD) patients has become a public health and economic concern. Therefore, effective and accessible dysphagia treatments are needed. As a fundamental rehabilitation of dysphagia, swallowing muscle exercises have received increased attention. Read More

J Texture Stud 2022 Jun 13. Epub 2022 Jun 13.

School of Mechanical Engineering, Jiangnan University, Wuxi, China.

Dysphagia, the swallowing disorder, is a common disease among the elders and stroke patients. Therefore, based on the bionic swallowing device (BSD) in vitro of similar human-tongue motion during swallowing, the development of functional food is necessary to improve the food swallowing quality of the deglutition disorders patients. In this study, the tongue motion was thoroughly investigated by extracting the characteristic data, and appropriate mechanisms in vitro were adopted to replicate the motion of the tongue swallowing according to the normal swallowing oropharyngeal data. Read More

JNMA J Nepal Med Assoc 2022 Jun 1;60(250):559-561. Epub 2022 Jun 1.

Department of Gastroenterology, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal.

Esophageal actinomycosis is a rare occurrence that presents a diagnostic challenge due to its vague clinical picture. The common symptoms include dysphagia, odynophagia and epigastric pain. These symptoms, although alarming, are usually non-specific. Read More

Gastric Cancer 2022 Jul 11;25(4):665-677. Epub 2022 Jun 11.

Asian Partnerships Office, Department of International Clinical Development/International Trials Management Section, Clinical Research Support Office, National Cancer Center Hospital, Tokyo, Japan.

The treatment landscape for gastric cancer (GC) is constantly evolving with therapies affecting all aspects of health-related quality of life (HRQoL) which need careful monitoring. While there are HRQoL measures designed specifically to capture issues relevant to patients with GC, these might be outdated and only relevant to patients in westernised cultures. This review identifies the patient-reported measures used to assess HRQoL of patients with GC and compares the HRQoL measures used across cultures including East Asia, where GC is more prevalent. Read More