3,467,474 results match your criteria Surgical Treatment of Vulvar Cancer
Eur J Phys Rehabil Med 2018 Dec 14. Epub 2018 Dec 14.
IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Background: Isolated patellar tendon rupture (PTR) is the final stage of a long-standing tendon chronic degeneration. PTR requires immediate repair in order to avoid important muscle retraction and tendon fibrosis. The aim was to describe the effects of a rehabilitation protocol after chronic-degenerative PTR on subjective functional outcomes, knee range of motion (ROM), size, and strength in a professional football player. Read More
J Gastrointest Cancer 2018 Dec 14. Epub 2018 Dec 14.
Department of Medical Oncology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Background: Adhesions and infiltration into adjacent tissues are present in about 12% of gastrointestinal (GIT) cancers. These adhesions have high potential risk of malignancy. Free resection margin is a predictor of good survival in such patients. Read More
Can J Anaesth 2018 Dec 13. Epub 2018 Dec 13.
Emergency and Essential Surgical Care Programme, World Health Organization, Geneva, Switzerland.
Neth Heart J 2018 Dec 13. Epub 2018 Dec 13.
Department of Cardiology, Amsterdam University Medical Centre, location AMC, Amsterdam, The Netherlands.
Aim: To determine differences in surgical procedures and clinical characteristics at the time of surgery between native bicuspid aortic valves (BAV) and tricuspid aortic valves (TAV) in patients being followed up after aortic valve surgery (AVS).
Methods: In this retrospective cohort study in a non-academic hospital, we identified patients who had a surgeon's report of the number of native valve cusps and were still being followed up. We selected patients with BAV and TAV, and used multivariable regression analyses to identify associations between BAV-TAV and pre-specified clinical characteristics. Read More
Forensic Sci Med Pathol 2018 Dec 13. Epub 2018 Dec 13.
Department of Humanities, University of Ferrara, Ferrara, Italy.
In this paper we present the study of a skull belonging to a young male from the Italian Bronze Age showing three perimortem injuries on the frontal and parietal bones; the peculiarity of the frontal injury is represented by its singular shape, which may be indicative of the weapon that caused the lesion. The aim of the present study is to examine the traumatic evidence in relation to possible etiological factors, in order to attempt to establish if the lesion occurred peri or post-mortem, and to evaluate if these traumatic injuries could be interpreted as an evidence of interpersonal violence, by combining anthropological, taphonomic and ESEM investigations. The combination of multidisciplinary methods of study can provide important new insights into inter-personal violence. Read More
Ann Surg Oncol 2018 Dec 13. Epub 2018 Dec 13.
Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Background: The time interval between CRT and surgery in rectal cancer patients is still the subject of debate. The aim of this study was to first evaluate the nationwide use of restaging magnetic resonance imaging (MRI) and its impact on timing of surgery, and, second, to evaluate the impact of timing of surgery after chemoradiotherapy (CRT) on short- and long-term outcomes.
Methods: Patients were selected from a collaborative rectal cancer research project including 71 Dutch centres, and were subdivided into two groups according to time interval from the start of preoperative CRT to surgery (< 14 and ≥ 14 weeks). Read More
Rev Endocr Metab Disord 2018 Dec 13. Epub 2018 Dec 13.
Medicover GmbH, Berlin/Hannover, Germany.
The pituitary gland and the hypothalamus can be affected by autoimmune-mediated structural and functional disruption. These autoimmune-mediated diseases occur more commonly in females and are often found during pregnancy or in the post-partum period. Autoimmune diseases can either affect parts of the pituitary or hypothalamus, or can involve both sellar and suprasellar structures. Read More
Obes Surg 2018 Dec 13. Epub 2018 Dec 13.
Department of Digestive Surgery, Archet II Hospital, University of Nice-Sophia-Antipolis, 151 Route de Saint-Antoine, 06200, Nice, France.
Background: Laparoscopic sleeve gastrectomy represents the most performed bariatric procedure in France. Staple line leak is the major short-term complication of the procedure. Patients with persistent fistula after sleeve gastrectomy, after failure of endoscopic and radiological treatment, are candidates for salvage surgery. Read More
Surg Case Rep 2018 Dec 13;4(1):143. Epub 2018 Dec 13.
Department of General surgery, Redcliffe Hospital, Redcliffe, QLD, 4020, Australia.
Background: Femoral hernia accounts for 3% of all the hernias, and in 0.5-5% of cases, the appendix can migrate through the femoral hernia and is called de Garengeot hernia. It is a very rare condition, and the incidence of appendicitis in this type of hernia is as low as 0. Read More
Pediatr Radiol 2018 Dec 13. Epub 2018 Dec 13.
Department of Diagnostic Radiology, Division of Pediatric Radiology,, Children's Hospital Colorado,, 13123 East 16th Ave., Mailbox B-463,, Aurora, CO, 80045, USA.
The term cloacal malformation is commonly used to describe the classic cloacal malformation where there is a single common urogenital and intestinal channel located at the expected site of the urethra. There is, however, a spectrum of cloacal abnormalities that differ from this classic type and are less well discussed in the radiologic and surgical literature. The aim of this pictorial essay is to familiarize radiologists with the anatomy, appropriate terminology and key prenatal imaging findings that differentiate the six entities that constitute the spectrum of cloacal abnormalities. Read More
Soc Psychiatry Psychiatr Epidemiol 2018 Dec 13. Epub 2018 Dec 13.
Division of Psychiatry, University College London, 6th Floor Maple House, 149 Tottenham Court Road, London, W1T 7BN, UK.
Purpose: Anxiety disorders are common. Prevalence is likely to be raised in people with hearing impairment, who experience higher rates of associated risk factors. We conducted, to our knowledge, the first systematic review of the prevalence and correlates of anxiety in people with hearing impairment. Read More
Surg Radiol Anat 2018 Dec 13. Epub 2018 Dec 13.
Department of General and Minimally Invasive Surgery, Centre Hospitalier de Luxembourg, 4, rue Ernest Barblé, 1210, Luxembourg City, Luxembourg.
Purpose: Our aim is to present a rare case of anatomic variation of the arterial blood supply to the liver because preoperative knowledge of hepatic vascular variations is mandatory in hepatic surgery and liver transplantation.
Methods: We present a case of unusual arterial blood supply to the liver, a right hepatic artery coming from the splenic artery, associated to a classical common hepatic artery and a left hepatic artery from the left gastric artery. Preoperative diagnosis was made using CT-scan and 3D reconstruction. Read More
Surg Radiol Anat 2018 Dec 13. Epub 2018 Dec 13.
Department of Plastic, Reconstructive and Aesthetic Surgery, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, Université Paris Descartes, Paris V, 20 rue Leblanc, 75908, Paris Cedex 15, France.
Purpose: While anatomical variations of the subscapular vessels are frequently encountered during axillary dissection, little is found in the literature. The aim of this cadaveric study was to define arterial and venous anatomical variations and frequencies of the subscapular vascular pedicle and its terminal/afferent vessels in women.
Methods: We performed 80 dissections of the axillary region on forty female formalin-embalmed cadavers. Read More
Eur Radiol 2018 Dec 13. Epub 2018 Dec 13.
Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan II Road, Guangzhou, 510080, People's Republic of China.
Objectives: Intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) provides information on both perfusion and diffusion and has been used to evaluate Crohn's disease (CD) activity and fibrosis in children; however, there are no reports on its use in adults. We aimed to determine its value for detecting and grading intestinal fibrosis in adults with CD compared with contrast-enhanced imaging and traditional diffusion-weighted imaging using surgical histopathology as a reference standard.
Methods: Twenty-four adults with CD underwent preoperative IVIM, traditional diffusion-weighted, and contrast-enhanced imaging. Read More
Int J Colorectal Dis 2018 Dec 13. Epub 2018 Dec 13.
Division of General Surgery, IRCCS Policlinico San Donato, Department of Biomedical Sciences of Health, University of Milan Medical School, San Donato Milanese, Milan, Italy.
Background: The importance of the defunctioning stoma on minimizing anastomotic leak in colorectal surgery is well established. However, a defunctioning stoma can substantially impact on quality of life (QoL). Circumferential purse-string approximation (PSA) and linear skin closure (LSC) are the most commonly performed surgical technique for reversal of stoma. Read More
J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):307-310. Epub 2018 Dec 4.
Division of Vascular and Endovascular Surgery, University of Massachusetts Medical School, Worcester, Mass.
Prosthetic graft infection is a rare and serious complication of thoracic endovascular aortic repair associated with high mortality and posing unique challenges for treatment. The prosthetic graft infection is often identified late as patients present with mild nonspecific symptoms. We describe the successful medical management and surgical explantation of an infected thoracic endograft with an aorta-bronchial fistula, using an inline reconstruction with an antibiotic-soaked synthetic graft. Read More
J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):296-300. Epub 2018 Dec 4.
Department of Thoracic and Cardiovascular Surgery, Trousseau University Hospital, Tours, France.
Aortic infection is a challenging condition. Fortunately, surgical revision of infected aorta with in situ reconstruction can provide long-term cure. The material for aortic repair remains an area of debate. Read More
J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):292-295. Epub 2018 Dec 4.
Division of Vascular Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah.
Radial artery aneurysms are exceedingly rare, with only a few reported cases of surgical revascularization. We describe a 25-year-old man who presented with severe ischemia of the right hand secondary to an idiopathic true radial artery aneurysm at the anatomic snuff box. The patient had embolic occlusions in his hand and fingers that were treated with catheter-directed thrombolysis. Read More
J Spine Surg 2018 Sep;4(3):684-686
University Spine Center Zurich, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
J Spine Surg 2018 Sep;4(3):668-676
IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
J Spine Surg 2018 Sep;4(3):624-629
Department of Neurosurgery, Universidad Militar Nueva Granada, Bogotá, Colombia.
Background: Spinal fractures are becoming more frequent and should be handled as a severe and endemic pathology that requires timely diagnosis and adequate treatment. The classification of the AOSpine is currently the classification used for this type of fractures, not only for its approach, but to predict surgical management.
Methods: These patients had spinal fracture reduction procedures done through percutaneous way with expander endovertebral implants, and intraosseous fixation using SpineJack intravertebral implants plus Cohesion cement. Read More
J Spine Surg 2018 Sep;4(3):610-615
Department of Neurosurgery, School of Medicine, University of Thessaly, Larissa, Greece.
Background: Surgical treatment of adult degenerative scoliosis (DS) always remains a challenge and often necessitates complex multilevel surgery via traditional open approaches. However, the severity of the procedure, in association with the fact that many of these patients are at an advanced age with several comorbidities, results in high rate of complications. Therefore, during the last decade, minimally invasive procedures have gained a place in the treatment of this pathology. Read More
J Spine Surg 2018 Sep;4(3):602-609
Department of Plastic and Reconstructive Surgery, Uppsala University Hospital, Uppsala, Sweden.
Background: The optimal treatment of symptomatic perineural (Tarlov) cysts is controversial. Numerous surgical techniques have been proposed with conflicting results. A series of Tarlov cysts treated with a novel surgical approach is presented. Read More
J Spine Surg 2018 Sep;4(3):594-601
Department of Orthopaedics, Iwai Orthopaedic Medical Hospital, Tokyo, Japan.
Background: Percutaneous endoscopic lumbar discectomy (PELD) is a relatively less invasive treatment for lumbar disc herniation (LDH). This study investigated the usefulness of a full-endoscopic system for PELD to treat L5 nerve root compression caused by lumbar foraminal stenosis (L5-LFS).
Methods: Between November 2016 and December 2017, a total of 10 patients with unilateral leg pain due to L5-LFS underwent surgery using a full-endoscopic system for PELD. Read More
J Spine Surg 2018 Sep;4(3):588-593
Department of Surgery, Queen's University, Kingston, ON, Canada.
Background: Routine investigations for asymptomatic patients undergoing low-risk surgery contribute little value to perioperative care, but these tests are still ordered in many centres. The primary purpose of this retrospective cohort study was to determine the prevalence of preoperative bloodwork for elective lumbar laminectomy and its association with intraoperative and postoperative complications. Secondary objectives were to determine the prevalence of intraoperative tranexamic acid administration, length of stay, and 30-day readmission. Read More
J Spine Surg 2018 Sep;4(3):553-559
Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Background: Chronic obstructive pulmonary disease (COPD) is a common cause of morbidity and mortality worldwide. Past literature has demonstrated that patients with COPD are at an increased risk of post-operative complications. We assessed the impact of COPD on 30-day outcomes following a 1- to 2-level posterior lumbar fusion (PLF). Read More
J Spine Surg 2018 Sep;4(3):501-508
Department of Orthopaedic Surgery, University of Rochester, Rochester, NY, USA.
Background: Ankylosing spondylitis (AS) is a rheumatologic condition that affects the axial skeleton. Structural changes render the spine susceptible to fractures, which can be treated operatively or non-operatively. The preferred surgical approach is not well established. Read More
IEEE Int Interdiscip Conf Cogn Methods Situat Aware Decis Support 2018 Jun 2;2018:77-82. Epub 2018 Aug 2.
Department of Anesthesia, MGH, Harvard Medical School, Boston, USA.
In the surgical setting, team members constantly deal with a high-demand operative environment that requires simultaneously processing a large amount of information. In certain situations, high demands imposed by surgical tasks and other sources may exceed team member's cognitive capacity, leading to cognitive overload which may place patient safety at risk. In the present study, we describe a novel approach to integrate an objective measure of team member's cognitive load with procedural, behavioral and contextual data from real-life cardiac surgeries. Read More
IEEE Robot Autom Lett 2019 Jan 19;4(1):145-152. Epub 2018 Nov 19.
Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH.
Robot-assisted medical interventions, such as robotic catheter ablation, often require the robot to perform tasks on a tissue surface. This paper presents a task-space motion planning method that generates actuation trajectories which steer the end- effector of the MRI-actuated robot along desired trajectories on the surface. The continuum robot is modeled using the pseudo-rigid-body model, where the continuum body of the robot is approximated by rigid links joined by flexible joints. Read More
J Biol Methods 2018 16;5(2). Epub 2018 Apr 16.
Department of Cancer Biology and Genetics, The Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA.
Uterine leiomyoma (UL) or fibroid is a benign smooth muscle tumor of the myometrium with a lifetime incidence of approximately 70%. ULs often require medical intervention due to severe symptoms such as heavy menstrual bleeding and abdominal pain. Although the most common and effective management of ULs is surgical removal, the invasive surgical procedure imposes physical and psychological burdens on the patients. Read More
Orthop J Sports Med 2018 Dec 7;6(12):2325967118811854. Epub 2018 Dec 7.
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Background: Avulsion fractures involving the tibial eminence are considered equivalent in terms of the cause to anterior cruciate ligament (ACL) tears; however, there are limited data comparing the outcomes of adolescent patients undergoing surgical fixation of a tibial eminence fracture (TEF) with those undergoing ACL reconstruction.
Purpose: To compare the clinical outcomes, subsequent ACL injury rates, and activity levels between adolescent patients who underwent TEF fixation with patients with midsubstance ACL tears who required acute reconstruction.
Study Design: Cohort study; Level of evidence, 3. Read More
Orthop J Sports Med 2018 Dec 4;6(12):2325967118811604. Epub 2018 Dec 4.
St John of God Hospital, Subiaco, Perth, Australia.
Background: Artificial ligaments have been developed and used in the treatment of ligamentous injuries since the 1970s. The early generation of artificial ligaments showed promising short-term results but resulted in high rates of rupture and inflammatory reaction in the surrounding tissues.
Purpose: To determine whether the use of Ligament Augmentation and Reconstruction System (LARS) ligaments is associated with the development of intra-articular foreign body reaction. Read More
Front Vet Sci 2018 28;5:291. Epub 2018 Nov 28.
Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California, Davis Davis, CA, United States.
Sepsis is the leading cause of critical illness and mortality in human beings and animals. Neutrophils are the primary effector cells of innate immunity during sepsis. Besides degranulation and phagocytosis, neutrophils also release neutrophil extracellular traps (NETs), composed of cell-free DNA, histones, and antimicrobial proteins. Read More
J Orthod Sci 2018 15;7:24. Epub 2018 Nov 15.
Department of Orthodontics, National Dental Centre Singapore, 5 Second Hospital Avenue, Singapore 168938.
Orthodontic traction of an impacted dilacerated maxillary central incisor is clinically challenging and often results in a long treatment duration. A case of an unusual dilacerated central incisor with a 90° crown-root angulation and palatally displaced crown is presented herein. Using a single stage open window exposure of the crown on the palatal aspect with light orthodontic traction force, the impacted dilacerated central incisor crown was successfully positioned in alignment with the contralateral incisor. Read More
Front Oncol 2018 28;8:558. Epub 2018 Nov 28.
Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, United States.
A subset of metastatic brain tumors occurs in deep-seated locations. Accessing and resecting these lesions can be associated with significant morbidity because it involves large craniotomies, extensive white matter dissection, prolonged retraction, and risk of inadvertent tissue injury. As a result, only palliative treatment options are typically offered for these lesions including observation, needle biopsies, and/or radiation therapy. Read More
Front Oncol 2018 28;8:440. Epub 2018 Nov 28.
Department of Therapeutic Radiology, Yale University, New Haven, CT, United States.
To investigate the impact of proton radiotherapy (PBT) on overall survival (OS) and evaluate PBT usage trends for patients with gliomas in the National Cancer Data Base (NCDB). Patients with a diagnosis of World Health Organization (WHO) Grade I-IV glioma treated with definitive radiation therapy (RT) between the years of 2004-13 were identified. Patients were stratified based on WHO Grade and photon radiotherapy (XRT) vs. Read More
Cureus 2018 Oct 9;10(10):e3433. Epub 2018 Oct 9.
Surgery, University of Utah, Salt Lake City, USA.
The purpose of this study was to retrospectively evaluate if a change in practice from January 2013 to August 2015 affected the rate of surgical-site infections following kidney transplantation at the single academic medical center. More patients were found to have a surgical-site infection when surgical antibiotics were only given intra-operatively despite a lower incidence of risk factors identified in the literature when compared to the cohort who received antibiotics intra-op and post-op for 24 hours. Read More
Cureus 2018 Oct 9;10(10):e3432. Epub 2018 Oct 9.
Otolaryngology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.
Cecal leiomyomas are rare benign tumors of smooth muscle arising from the colonic muscularis mucosa or muscularis propria. They are usually asymptomatic in nature and, if symptomatic, may present as pain in the abdomen, intestinal obstruction, or bleeding. In some cases, leiomyoma can cause free perforation leading to peritonitis. Read More
Cureus 2018 Oct 9;10(10):e3431. Epub 2018 Oct 9.
General Surgery, Shiraz University of Medical Sciences, Shiraz, IRN.
Purpose The aim of the current study was to report the surgical outcome and complications of jejunostomy with enteroenterostomy for enteral nutrition (EN) in critically ill trauma patients with prolonged nasogastric (NG) nutrition. Methods This cross-sectional study was carried out in a level I trauma center in Shiraz, southern Iran during a one-year period from 2016 to 2017. We included a total number of 30 patients with severe trauma admitted to the intensive care unit (ICU) with more than three months NG nutrition and bowel atrophy. Read More
Cureus 2018 Oct 9;10(10):e3430. Epub 2018 Oct 9.
Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, AUS.
This report is of a rare case involving a 27-year-old female who presented to the hospital with the pathological couplet of colocolic intussusception and cecal bascule causing bowel obstruction. Up to the time of presentation to the hospital, this patient had not undergone a full investigation for a known iron deficiency, anemia. Subsequently, during the emergency admission and after having an operative surgical procedure, the patient was found to have both a congenitally malpositioned cecum and a benign colonic polyp-forming condition. Read More
Cureus 2018 Oct 8;10(10):e3424. Epub 2018 Oct 8.
Otolaryngology, Aristotle University of Thessaloniki, Thessalonki, GRC.
Nikolai Ivanovich Pirogov is considered one of the most important anatomists and surgeons in the history of medicine. The Russian physician conducted more than 11,000 dissections and meticulously studied human anatomy, discovering important anatomical regions such as Pirogov's triangle. Pirogov developed surgical methods and techniques used by physicians for many decades such as Pirogov's amputation. Read More
Cureus 2018 Oct 8;10(10):e3422. Epub 2018 Oct 8.
Surgery, Stanford Hospital, Stanford, USA.
Introduction Patient care in the trauma-surgical intensive care unit (SICU) requires trust and effective communication between nurses and physicians. Our SICU suffered from poor communication and trust between nurses and physicians, negatively impacting the working environment and, potentially, patient care. Methods A SICU Task Force studied communication practices and identified areas for improvement, leading to several interventions. Read More
Oncoimmunology 2019 11;8(1):e1526614. Epub 2018 Oct 11.
Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Complete tumour devascularisation (CTD) is a surgical technique which entails the complete disruption by ligation or cutting of afferent and efferent tumour vasculature which remains in situ. In some animal models, CTD induces immune responses that lead to regression of distant metastases and protective immunity. Read More
Oncoimmunology 2019 5;8(1):e1512943. Epub 2018 Sep 5.
Project neuroArm, Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Meningioma is the most common brain tumor in adults. Surgical resection remains the primary treatment. No chemotherapy exists. Read More
Oncoimmunology 2019 29;8(1):e1483303. Epub 2018 Oct 29.
Departments of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Determining prostate cancer (PCa) aggressiveness and reclassification are critical events during the treatment of localized disease and for patients undergoing active surveillance (AS). Since T cells play major roles in cancer surveillance and elimination, we aimed to identify genetic biomarkers related to T cell cancer immune response which are predictive of aggressiveness and reclassification risks in localized PCa. The genotypes of 3,586 single nucleotide polymorphisms (SNPs) from T cell cancer immune response pathways were analyzed in 1762 patients with localized disease and 393 who elected AS. Read More
J Clin Imaging Sci 2018 15;8:46. Epub 2018 Nov 15.
Division of Gastroenterology and Hepatology, University of Kentucky, College of Medicine, Lexington, Kentucky, USA.
Endoscopic intervention is well validated for the control of upper gastrointestinal bleeding (UGIB). In cases of refractory bleeding, transarterial embolization is a safe and effective alternative. Ethylene vinyl alcohol (EVOH) commonly known as Onyx is an inherently black liquid embolic approved for use in cerebrovascular arteriovenous malformations and is increasingly used as an embolic agent in multiple peripheral and visceral territories. Read More
J Clin Imaging Sci 2018 15;8:42. Epub 2018 Nov 15.
Department of Radiology, Tuen Mun Hospital, Tuen Mun, Hong Kong.
Laryngocele is a rare entity and can be defined as an abnormal cystic dilatation of saccule of the laryngeal ventricle with communication to the lumen of larynx. Laryngopyocele is a rare complication of laryngocele when it is infected. Patients may present with fever, neck swelling, shortness of breath, and hoarseness. Read More
Mol Clin Oncol 2018 Dec 4;9(6):697-701. Epub 2018 Oct 4.
Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
The present study aimed to clarify the risk factors for recurrence of stage II colon cancer in patients and to determine possible treatment options for postoperative adjuvant chemotherapy. A prediction model for recurrence in patients with stage II colon cancer after curative surgical resection was developed. The present study retrospectively investigated 436 patients who underwent curative resection for stage II colon cancer at Osaka International Cancer Institute and Yao Municipal Hospital between 2004 and 2012. Read More
Mol Clin Oncol 2018 Dec 5;9(6):661-665. Epub 2018 Oct 5.
Department of Pathology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo 113-0021, Japan.
Primary gastric undifferentiated pleomorphic sarcoma (UPS) is a rare disease with insufficient long-term follow-up data. In the present study, a 70-year-old male complained of abdominal fullness and visited our hospital. Abdominal computed tomography revealed a large tumor in the upper part of the stomach, which was accompanied by smaller tumors in the small intestinal mesentery. Read More
Mol Clin Oncol 2018 Dec 25;9(6):640-646. Epub 2018 Sep 25.
Division of Chest Surgery, Department of Surgery, Showa University School of Medicine, Tokyo 142-8666, Japan.
The expression levels of thymidine phosphorylase (), dihydropyrimidine dehydrogenase (), thymidylate synthase () and orotate phosphoribosyltransferase () may predict the clinical efficacy of 5-fluorouracil-based chemotherapy in patients with cancer. We herein investigated the differences in the mRNA levels of these enzymes in non-small-cell lung cancer (NSCLC) and evaluated their prognostic value for NSCLC treated by surgical resection. The intratumoral mRNA levels of , and were quantified in 66 patients with pathological stage I and II NSCLC (adenocarcinoma or squamous cell carcinoma) following complete resection according to the Danenberg Tumor Profile method. Read More