19,530 results match your criteria Surgical Treatment of Vaginal Cancer


Prevalence of cervical cancer and pre-cancerous lesions among unscreened Women in Kumasi, Ghana.

Medicine (Baltimore) 2019 Mar;98(13):e14600

Department of Pathology, School of Biomedical and Allied Health Sciences, College of Health Sciences, University of Ghana, Ghana.

Ghana does not have a universal population-based cervical cancer screening program and there is very limited information about the distribution of cervical epithelial cell lesions. This study provides evidence that a moderately high prevalence of cervical cancer and precancerous lesions exists among unscreened women in Kumasi.The prevalence of cervical epithelial cell abnormalities among a cross-section of women attending cervical cancer screening for the first time in a suburb of Ghana from 2011 to 2014 was studied. Read More

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http://dx.doi.org/10.1097/MD.0000000000014600DOI Listing
March 2019
1 Read
5.723 Impact Factor

Extraperitoneal radical trachelectomy with pelvic lymphadenectomy.

Int J Gynecol Cancer 2019 Mar 26. Epub 2019 Mar 26.

Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan

Radical trachelectomy combined with pelvic lymphadenectomy has been used to treat patients with early-stage cervical cancer who wish to preserve their fertility. Vaginal, abdominal, laparoscopic, and robotic approaches have been employed during this procedure, but all cause peritoneal damage, which could result in periadnexal adhesion. As periadnexal adhesion can lead to female infertility due to restricted sweeping of the fimbria over the ovary, it is important to minimize peritoneal damage during the fertility-preserving surgery. Read More

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http://dx.doi.org/10.1136/ijgc-2018-000196DOI Listing
March 2019
1 Read

Predictive factors of severe perioperative morbidity of radical hysterectomy with lymphadenectomy in early-stage cervical cancer: A French prospective multicentric cohort of 248 patients.

Eur J Surg Oncol 2019 04 17;45(4):650-658. Epub 2018 Oct 17.

Gynecologic and Breast Oncologic Surgery Department, Georges Pompidou European, Hospital, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Faculty of Medicine, Paris, France.

Objective: The purpose of this study was to assess the postoperative morbidity after radical hysterectomy (RH) for early-stage cervical cancer and to determine risk factors of severe perioperative morbidity.

Methods: Data of two prospective trials on sentinel node biopsy for cervical cancer (SENTICOL I & II) were analysed. Patients having a radical hysterectomy were included between 2005 and 2012 from 25 French oncologic centers. Read More

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http://dx.doi.org/10.1016/j.ejso.2018.10.057DOI Listing
April 2019
2 Reads

Mixed adenoneuroendocrine carcinoma of the urethra.

BMJ Case Rep 2019 Mar 21;12(3). Epub 2019 Mar 21.

Department of Urology, Royal Free London NHS Foundation Trust, London, UK.

Mixed adenoneuroendocrine carcinoma (MANEC) is a rare tumour found predominantly in the gastrointestinal tract. Comprising adenocarcinomatous and neuroendocrine components, MANEC have been reported in the bladder. We report the first case to our knowledge of a MANEC arising in the urethra. Read More

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http://dx.doi.org/10.1136/bcr-2018-227948DOI Listing
March 2019
1 Read

Palliative interventions for controlling vaginal bleeding in advanced cervical cancer.

Cochrane Database Syst Rev 2019 03 19;3:CD011000. Epub 2019 Mar 19.

Effective Care Research Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, PMB 5001, Nnewi, Anambra State, Nigeria.

Background: This is an updated version of the original Cochrane review published in Issue 5, 2015.Cervical cancer is the fourth most common cancer among women worldwide, with estimated 569,847 new diagnoses and 311,365 deaths per year. However, incidence and stage at diagnosis vary greatly between geographic areas and are largely dependent on the availability of a robust population screening programme. Read More

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http://dx.doi.org/10.1002/14651858.CD011000.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423555PMC
March 2019
1 Read

[Cost-effectiveness analysis of cervical cancer screening strategies in urban China].

Zhonghua Zhong Liu Za Zhi 2019 Feb;41(2):154-160

Department of Epidemiology and Biostatistics, West China School of Public Health, Sichuan University, Chengdu 610041, China.

To explore the most economically feasible cervical cancer screening strategies in urban China. A series of Markov models were constructed to evaluate health and economic outcomes of different screening strategies. There were 24 screening strategies including four screening methods: liquid-based cytology (LBC), human papillomavirus (HPV) DNA genotyping, HPV DNA genotyping with LBC triage (HPV DNA+ LBC), HPV DNA genotyping and LBC co-testing (HPV DNA-LBC), along with three intervals (every 1, 3 or 5 years) and two starting age for screening (30 or 35 years old) were compared. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2019.02.015DOI Listing
February 2019
7 Reads

Age of Initiation of Cervical Cancer Screening-Reply.

JAMA 2019 02;321(6):612

Veterans Affairs Palo Alto Health Care System, Palo Alto, California.

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http://dx.doi.org/10.1001/jama.2018.19089DOI Listing
February 2019
1 Read

Age of Initiation of Cervical Cancer Screening.

JAMA 2019 02;321(6):611-612

Department of Family Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1001/jama.2018.19085DOI Listing
February 2019
2 Reads

Treatment modalities for recurrent high-grade vaginal intraepithelial neoplasia.

J Gynecol Oncol 2019 Mar 8;30(2):e20. Epub 2018 Nov 8.

Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy.

Objective: We have investigated outcomes of women presenting with recurrent high-grade vaginal intra-epithelial neoplasia.

Methods: Data of consecutive women diagnosed with recurrent high-grade vaginal intra-epithelial neoplasia after primary treatment(s) were retrieved. Risk of developing new recurrence over the time was assessed using Kaplan-Meier and Cox models. Read More

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http://dx.doi.org/10.3802/jgo.2019.30.e20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393627PMC
March 2019
1 Read

A Study of Pap Smears in HIV-Positive and HIV-Negative Women from a Tertiary Care Center in South India.

Acta Cytol 2019 5;63(1):50-55. Epub 2019 Feb 5.

Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India.

Objectives: The aim of this work was to study the spectrum of epithelial abnormalities on Pap smears of HIV-positive women categorized as per the Bethesda System of Reporting Cervical Cytology, to correlate them with CD4 lymphocyte counts, and to compare them with the spectrum of abnormalities seen in a HIV-negative control group. Study Design and Methodology: The present study was a 6-year retrospective study conducted in the Department of Pathology at Kasturba Medical College, Mangalore, which included 150 Pap smears from HIV-positive and HIV-negative women, respectively. The Pap-stained slides of the cases were retrieved and studied. Read More

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http://dx.doi.org/10.1159/000496211DOI Listing
March 2019
13 Reads

[Clinicopathological analysis of cervical basaloid squamous cell carcinoma].

Zhonghua Fu Chan Ke Za Zhi 2019 Jan;54(1):7-12

Department of Pathology, General Hospital of PLA, Beijing 100853, China.

To investigate the clinical and histopathological features of cervical basal squamous cell carcinoma (BSCC). A retrospective analysis of 10 cases of cervical BSCC was carried out. The clinical data and all the pathological sections were reviewed, the related immunohistochemical results were statistically analyzed, the clinicopathological features were analyzed, and then followed the prognosis. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-567x.2019.01.003DOI Listing
January 2019
13 Reads

[A Case of Laparoscopic Resection for Locally Advanced Primary Rectal Cancer after Neoadjuvant Chemotherapy].

Gan To Kagaku Ryoho 2018 Dec;45(13):1922-1924

Dept. of Gastroenterological Surgery, Hirosaki University School of Medicine.

We treateda 70-year-oldfemale patient with locally advancedrectal cancer accompaniedby metastases to other organs. Three courses of S-1 plus oxaliplatin(SOX)therapy were administered as neoadjuvant chemotherapy(NAC), andthe cancer was subsequently treatedwith laparoscopic rectal resection. She hadvisiteda physician with a chief complaint of melena. Read More

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December 2018
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[A Case of Elderly Advanced Rectal Cancer Treated with Abdominoperineal Resection after 16 Months of Chemoradiotherapy].

Gan To Kagaku Ryoho 2018 Dec;45(13):2171-2173

Dept. of Surgery, NTT West Osaka Hospital.

An 81-year-old woman underwent preoperative chemoradiotherapy(CRT)for advanced lower rectal cancer with vaginal invasion. However, she refused surgery and received additional radiotherapy. We detected a rectal-vaginal leak, so we performed ileostomy with double orifices and chemotherapy. Read More

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December 2018
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Patterns of recurrence and prognosis in locally advanced FIGO stage IB2 to IIB cervical cancer: Retrospective multicentre study from the FRANCOGYN group.

Eur J Surg Oncol 2019 04 30;45(4):659-665. Epub 2018 Dec 30.

Department of Gynaecology and Obstetrics, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), University Pierre and Marie Curie, Paris 6, Institut Universitaire de Cancérologie (IUC), 4 rue de la Chine, 75020, Paris, France; INSERM UMR_S_938, University Pierre et Marie Curie, Paris 6, 27 rue de Chaligny, 75012, Paris, France.

Introduction: Evidence-based data describing patterns of recurrence and prognosis in women with FIGO stage IB2 to IIB locally advanced cervical cancer (LACC) are scarce. The purpose of this study was to analyse patterns of recurrence in LACC and their correlation with prognosis, depending on FIGO stage, lymph node (LN) status and treatment modalities. The endpoints of this study were the type of recurrence (locoregional or distant, and time to recurrence), the recurrence free survival, the overall survival and the cumulative incidence for both locoregional and distant recurrence. Read More

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http://dx.doi.org/10.1016/j.ejso.2018.11.014DOI Listing
April 2019
6 Reads

Cancer Screening and Prevention Highlights in Gynecologic Cancer.

Obstet Gynecol Clin North Am 2019 Mar;46(1):19-36

Division of Gynecology Oncology, Department of Obstetrics and Gynecology, University of Virginia, University of Virginia Medical Center, PO Box 800712, Charlottesville, VA 22908, USA.

This article provides an up-to-date summary of screening approaches and key strategies in prevention of gynecologic malignancies. The Pap smear is the only proven screening intervention in the field of gynecologic oncology. Women should receive treatment for precancerous conditions of the cervix, vulva, vagina, and endometrial lining. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898545183009
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http://dx.doi.org/10.1016/j.ogc.2018.09.002DOI Listing
March 2019
13 Reads

DIY smear tests: are they the answer to falling cervical screening rates?

Authors:
Jacqui Wise

BMJ 2019 Jan 23;364:l361. Epub 2019 Jan 23.

London.

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http://dx.doi.org/10.1136/bmj.l361DOI Listing
January 2019

Vaginal hysterectomy with or without bilateral salpingo-oophorectomy may be an alternative treatment for endometrial cancer patients with medical co-morbidities precluding standard surgical procedures: a systematic review.

Int J Gynecol Cancer 2019 Jan 18. Epub 2019 Jan 18.

Department of Obstetrics and Gynecology, University Medical Center Groningen, Groningen, The Netherlands.

Objective: Vaginal hysterectomy with bilateral salpingo-oophorectomy may be an alternative strategy for patients with low-risk endometrial cancer and medical co-morbidities precluding laparoscopic or abdominal procedures. The current study evaluates the prevalence of co-existent ovarian malignancy in patients with endometrial cancer and the influence of bilateral salpingo-oophorectomy on survival outcomes in these patients.

Methods: Medline and EMBASE were searched for studies published between January 1, 2000 and November 20, 2017 that investigated (1) the prevalence of co-existing ovarian malignancy (either metastases or primary synchronous ovarian cancer in women with endometrial cancer, and (2) the influence of bilateral salpingo-oophorectomy on recurrence and/or survival rates. Read More

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http://dx.doi.org/10.1136/ijgc-2018-000015DOI Listing
January 2019
4 Reads

Diagnostic Test Accuracy Review of Cytology for Squamous Intraepithelial Lesion and Squamous Cell Carcinoma of Uterine Cervix.

J Korean Med Sci 2019 Jan 2;34(2):e16. Epub 2019 Jan 2.

Department of Pathology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

Background: Even though cervico-vaginal smears have been used as a primary screening test for cervical carcinoma, the diagnostic accuracy has been controversial. The present study aimed to evaluate the diagnostic accuracy of cytology for squamous intraepithelial lesion (SIL) and squamous cell carcinoma (SqCC) of the uterine cervix through a diagnostic test accuracy (DTA) review.

Methods: A DTA review was performed using 38 eligible studies that showed concordance between cytology and histology. Read More

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http://dx.doi.org/10.3346/jkms.2019.34.e16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327093PMC
January 2019
2 Reads
1.253 Impact Factor

Feasibility, validity and acceptability of self-collected samples for human papillomavirus (HPV) testing in rural Malawi.

Malawi Med J 2018 06;30(2):61-66

Division of Infectious Diseases, Department of Internal Medicine, The Ohio State University, Columbus, USA.

Aim: The World Health Organization (WHO) recently endorsed human papillomavirus (HPV) testing as a cervical cancer screening method in countries without established programs. Self-collection for HPV testing may be an effective way to expand screening. Our objective was to assess the feasibility, validity, and acceptability of self-collection for HPV testing in a population of care-seeking, unscreened women in rural Malawi. Read More

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http://dx.doi.org/10.4314/mmj.v30i2.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307066PMC
June 2018
2 Reads

[Analysis of cervical cancer screening results in women aged 50 and older in Beijing and Guizhou].

Authors:
G Z Guo Y Zhao

Zhonghua Zhong Liu Za Zhi 2018 Dec;40(12):922-926

Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.

To analyze the screening results of cervical cancer in elderly women in Beijing and Guizhou. To compare the screening effectiveness of cervical cancer in elderly women in different areas. A retrospective analysis was performed on the screening data of elderly women (≥50 years) who had examination at cervical lesion clinic in Peking University People's Hospital and Affiliated Hospital of Guizhou Medical University from January 2013 to January 2014, with histopathology as the gold standard, to compare screening effectiveness of cervical cytology or HPV detection for elderly women in cervical cancer screening in the two regions. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2018.12.010DOI Listing
December 2018
1 Read

Analytical performance evaluation of the HPV OncoCheck assay for detection of high-risk HPV infection in liquid-based cervical samples.

Exp Mol Pathol 2019 02 31;106:149-156. Epub 2018 Dec 31.

Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju, Gangwon, South Korea.

Recent studies have demonstrated low specificity (false positive) of human papillomavirus (HPV) DNA testing for the screening and diagnosis of cervical samples. Therefore, we evaluated the performance of the HPV OncoCheck assay, which is an HPV E6/E7 mRNA-based assay, for the detection of 16 high-risk (HR)-HPVs including HPV 16 and HPV 18 genotypes in cervical samples using multiplex reverse transcriptase-quantitative PCR. In the present study, the analytical performance of the assay was evaluated using 16 HPV single strand DNAs. Read More

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http://dx.doi.org/10.1016/j.yexmp.2018.12.008DOI Listing
February 2019
2 Reads

Histologic Correlation and Clinical Significance of Atypical Glandular Cells on Cervical Pap Tests: Analysis of 540 Cases at a Single Institution.

Cancer Invest 2019 2;37(1):8-15. Epub 2019 Jan 2.

b Department of Obstetrics and Gynecology , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.

The aim of this study is to determine the rate of clinically significant histopathologic lesions in women identified with atypical glandular cells (AGC). Five-hundered and forty patients with AGC, from a cohort of 1013 with AGC, met inclusion criteria for this study by having a proper histologic evaluation. Clinically significant histologic results were obtained in 170 cases with AGC (31. Read More

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http://dx.doi.org/10.1080/07357907.2018.1547738DOI Listing

Detection of HPV mRNA in Self-collected Vaginal Samples Among Women at 69-70 Years of Age.

Anticancer Res 2019 Jan;39(1):381-386

Department of Obstetrics and Gynecology, Skåne University Hospital, Lund University, Lund, Sweden.

Background/aim: Cervical cancer is associated with poorer diagnosis among the elderly and pap-smear screening has a lower sensitivity. Self-sampling for detection of high-risk human papillomavirus (hr-HPV) may be an alternative screening method. The aim of this study was to analyze the response rate to vaginal HPV self-sampling and the HPV mRNA prevalence among women 69-70 years. Read More

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http://dx.doi.org/10.21873/anticanres.13123DOI Listing
January 2019
3 Reads

[Microcystic, elongated and fragmented invasion pattern in endometrial carcinoma: the clinicopathology analysis].

Zhonghua Fu Chan Ke Za Zhi 2018 Dec;53(12):811-815

Department of Pathology, Peking University People's Hospital, Beijing 100044, China.

To assess the clinical value for the clinicopathological features of microcystic elongated and fragmented (MELF) invasion in endometrial carcinoma (EEC) . The clinicopathological data of 108 cases of endometrial carcinoma with total hysterectomy, bilateral adnexectomy, and pelvic dissection were retrospectively analysis in Peking University People's Hospital from April 2015 to October 2016. Twenty-five patients with endometrial carcinoma showing MELF invasion pattern were collected. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-567x.2018.12.003DOI Listing
December 2018
3 Reads

Factors Influencing Knowledge and Practice Regarding Cervical Cancer and Pap smear Testing among Omani Women

Asian Pac J Cancer Prev 2018 Dec 25;19(12):3367-3374. Epub 2018 Dec 25.

Department of Allied Health Sciences, College of Medicine and Health Sciences, Sultan Qaboos University, Sultanate of Oman. Email:

Background: Knowledge of cervical cancer and performance of Pap smear testing are influenced by several sociodemographic factors. This study aimed to describe the effect of relevant variables on knowledge and compliance with guidelines in Oman. Methods: In this cross-sectional survey, participants were divided into three groups: patients who attended Outpatient Gynecology Department, female medical staff and university graduate students. Read More

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http://dx.doi.org/10.31557/APJCP.2018.19.12.3367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428537PMC
December 2018
4 Reads

Cervical Cancer Screening Programs in Europe: The Transition Towards HPV Vaccination and Population-Based HPV Testing.

Viruses 2018 12 19;10(12). Epub 2018 Dec 19.

Department of Biological Sciences, University of Cyprus, 1 University Avenue, Aglantzia 2109, Nicosia, Cyprus.

Cervical cancer is the fourth most frequently occurring cancer in women around the world and can affect them during their reproductive years. Since the development of the Papanicolaou (Pap) test, screening has been essential in identifying cervical cancer at a treatable stage. With the identification of the human papillomavirus (HPV) as the causative agent of essentially all cervical cancer cases, HPV molecular screening tests and HPV vaccines for primary prevention against the virus have been developed. Read More

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http://www.mdpi.com/1999-4915/10/12/729
Publisher Site
http://dx.doi.org/10.3390/v10120729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315375PMC
December 2018
9 Reads

Piver Type II vs. Type III Hysterectomy in the Treatment of Early-Stage Cervical Cancer: Midterm Follow-up Results of a Randomized Controlled Trial.

Front Oncol 2018 28;8:568. Epub 2018 Nov 28.

Department of Obstetrics and Gynecology, Chinese PLA General Hospital, Beijing, China.

With the expansion of value-based medicine, we explore whether using type III hysterectomy to treat low-risk, early-stage cervical cancer constitutes overtreatment. In present study, we evaluate the midterm safety and postoperative quality of life of patients who underwent type II hysterectomy vs. type III hysterectomy with systematic lymphadenectomy for low-risk early-stage cervical cancer (International Federation of Gynecology and Obstetrics (FIGO) IA2-IB1; maximum tumor diameter < 2 cm). Read More

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http://dx.doi.org/10.3389/fonc.2018.00568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280766PMC
November 2018
1 Read

Time Intervals Between Prior Cervical Conization and Posterior Hysterectomy Influence Postoperative Infection in Patients with Cervical Intraepithelial Neoplasia or Cancer.

Med Sci Monit 2018 Dec 14;24:9063-9072. Epub 2018 Dec 14.

Department of Gynecology, Maternal and Child Care Service Center, Zhenjiang 4th Hospital, Zhenjiang, Jiangsu, China (mainland).

BACKGROUND This study was conducted to observe the influence of different time intervals between prior cervical conization and posterior hysterectomy on postoperative infection in female patients with cervical intraepithelial neoplasia or cancer. MATERIAL AND METHODS Medical records of 170 patients who underwent hysterectomy following cervical conization between November 2010 and September 2016 at the Zhenjiang 4th Hospital were reviewed. According to the interval between hysterectomy and cervical conization, patients were classified into 1-2-week, 4-5-week, and 6-week groups. Read More

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http://dx.doi.org/10.12659/MSM.911892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302663PMC
December 2018
1 Read

[Embolization of the hypogastric artery in postpartum haemorrhage. Case report].

Orv Hetil 2018 Sep;159(39):1602-1606

Szolnoki Angiográfiás és Intervenciós Központ, Avas Egészségügyi Centrum Kft. Szolnok.

Selective embolization of the hypogastric artery is nowadays commonly used for the haemostasis of gynaecological cancer patients. Also re-embolization is possible in the cases of repeated bleedings. We present this method based on the summary of three obstetrical patients in our hospital. Read More

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http://dx.doi.org/10.1556/650.2018.31186DOI Listing
September 2018

Socioeconomic and lifestyle factors associated with HPV infection in pregnant women: a matched case-control study in Beijing, China.

Reprod Health 2018 Dec 6;15(1):200. Epub 2018 Dec 6.

Department of Biomedical Sciences, Mercer University School of Medicine, Macon, GA, USA.

Background: Human papillomavirus (HPV) infection plays key role in the development of cervical cancer. The purpose of this study was to investigate socioeconomic and lifestyle factors associated with HPV infection in pregnant women in Beijing, China.

Methods: An age matched case-control study designed with 66 women as the case group (HPV positive) and 132 women as the control group (HPV negative) was carried out in two hospitals in Beijing. Read More

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http://dx.doi.org/10.1186/s12978-018-0645-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282257PMC
December 2018
2 Reads

[Evaluation of 114 abnormal Pap smear follow-up in ambulatory care.]

Sante Publique 2018 July August;30(4):527-532

Aim: In France, cervical cancer screening has led to a decrease in mortality, though it could be optimized by improving the management of abnormal cytology. The aim was to evaluate the follow-up of women with abnormal Pap smear prescribed by an ambulatory health professional, compared to the ANAES guidelines of 2002.

Method: Quantitative monocentric and retrospective study of 120 women with abnormal Pap smear performed before October 2014 in the French department of the Loire. Read More

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http://www.cairn.info/revue-sante-publique-2018-4-page-527.h
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http://dx.doi.org/10.3917/spub.185.0527DOI Listing
February 2019
13 Reads

[Analysis of the first test of ASC-US smears by general practitioners of the Maine-et-Loire in 2014.]

Sante Publique 2018 July August;30(4):499-505

Introduction: During the study, the HAS (French Board of Health) recommended 3 options for the first test (C1) in case of presence of ASC-US: a smear to be carried out after 6 months, an HPV test or a colposcopy.Our main objective was to find out which C1 option was chosen. The secondary objectives were to evaluate the number of C1's carried out by general practitioners, the follow-up rate and that of adapted C1 smear reports. Read More

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http://dx.doi.org/10.3917/spub.185.0499DOI Listing
February 2019

Challenges and Opportunities in Adolescent Gynecology Patients with Surgically-Treated Congenital and Acquired Anomalies: Transition of Care from Pediatric to Adult Surgery.

J Pediatr Adolesc Gynecol 2019 Apr 5;32(2):103-109. Epub 2018 Dec 5.

John R Oishei Hospital, University of Buffalo, Buffalo, NY.

The transition from adolescence to young adulthood in patients with reproductive health care needs such as disorders of sexual development and congenital anomalies is a complex process that occurs over several years. The transition process for these patients is still poorly understood. The patients with disorders of sexual development and reproductive issues have specific and unique issues regarding timing of disclosure of diagnosis, genital examinations, gonadectomy, vaginal treatments, surgical procedures, hormone replacement therapy, use of long-term medication, and potential cancer screening. Read More

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http://dx.doi.org/10.1016/j.jpag.2018.11.007DOI Listing
April 2019
6 Reads

Detecting cervical precancer and reaching underscreened women by using HPV testing on self samples: updated meta-analyses.

BMJ 2018 12 5;363:k4823. Epub 2018 Dec 5.

Global Coalition Against Cervical Cancer, Durham, NC, USA.

Objective: To evaluate the diagnostic accuracy of high-risk human papillomavirus (hrHPV) assays on self samples and the efficacy of self sampling strategies to reach underscreened women.

Design: Updated meta-analysis.

Data Sources: Medline (PubMed), Embase, and CENTRAL from 1 January 2013 to 15 April 2018 (accuracy review), and 1 January 2014 to 15 April 2018 (participation review). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278587PMC
http://dx.doi.org/10.1136/bmj.k4823DOI Listing
December 2018
3 Reads

The impact of regional screening policies on the diffusion of cancer screening participation in Belgium: time trends in educational inequalities in Flanders and Wallonia.

BMC Health Serv Res 2018 Dec 4;18(1):943. Epub 2018 Dec 4.

Health and Demographic Research, Department of Sociology, Ghent University, Korte Meer 5, 9000, Ghent, Belgium.

Background: We investigate whether the extent of educational inequalities in the use of Pap smears (cervical cancer screening) and mammograms (breast cancer screening) in Belgium has changed over time in accordance with the pattern predicted by diffusion of innovation theory, as well as how the regional cancer screening policies of Flanders and Wallonia influence this pattern.

Methods: Data were obtained from five successive cross-sectional waves (1997-2001-2004-2008-2013) of the Belgian Health Interview Survey. Final sample sizes consisted of 8988 women aged 25-64 years for cervical cancer screening and 4194 women aged 50-69 years for breast cancer screening. Read More

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http://dx.doi.org/10.1186/s12913-018-3746-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280447PMC
December 2018

Management of placental site trophoblastic tumor: Two case reports.

Medicine (Baltimore) 2018 Nov;97(48):e13439

Interdisciplinary Department of Medicine, Gynecology and Obstetrics Clinic, University of Bari.

Rationale: Placental site trophoblastic tumor (PSTT) is a very rare malignant tumor, belonging to a family of pregnancy-related illnesses, called gestational trophoblastic diseases (GTD). Less than 300 cases of PSTT have been reported in literature, with an incidence of ≈ 1/50,000-100,000 pregnancies representing only 0.23% to 3. Read More

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http://dx.doi.org/10.1097/MD.0000000000013439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283185PMC
November 2018
18 Reads

Primary squamous cell carcinoma of the endometrium in a woman of perimenopausal age: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13418

Department of Gynecology.

Rationale: Primary squamous cell carcinoma of the endometrium (PSCCE) is a rare entity, and only sporadic cases have been reported in the literature since the 1st report in 1892. This report describes a case of a perimenopausal woman with PSCCE.

Patient Concerns: A 47-year-old, human papilloma virus type 16-positive, perimenopausal woman was admitted to our hospital with irregular vaginal bleeding for 6 months and secondary anemia. Read More

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http://dx.doi.org/10.1097/MD.0000000000013418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283105PMC
November 2018
3 Reads
5.723 Impact Factor

[Enrico Bottini (1835-1903), Italian Physician and Politician: A Master of Antisepsis and a Pioneer of Modern Surgery].

Acta Med Hist Adriat 2018 Dec;16(2):293-302

Università di Genova, Genova, Italia

Enrico Bottini (Stradella, Pavia, 7 September 1835 - Porto Maurizio, Sanremo, 11 March 1903) was a multifaceted surgeon, who left a strong mark in modern surgery, not only Italian but worldwide. A pupil of Porta and Ribeti, as well as the distinguished French surgeon and anatomist Charles-Marie-Édouard Chassaignac, he has dedicated himself throughout his career to various areas of medicine, ranging from bacteriology and anti-sepsis (use of a derivative of phenic acid) to urological surgery (the so-called "endo-urethral galva-cauterization", also called Bottini's operation, or Perineal incision according to Bottini). He has also successfully dedicated himself to gynecology (trans-vaginal hysterectomy for uterine cancer and surgical treatment of vesicovaginal fistulas), maxillofacial surgery (endo-oral resection of the maxilla, subperiosteal resection of the mandible for the treatment of the stable jaw, total amputation of the larynx and the tongue for carcinomas), the dermosurgery (use of the electrocautery), and the vascular surgery (resection of the inferior vena cava). Read More

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December 2018
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The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre)cancer in Chinese women.

BMC Cancer 2018 Nov 29;18(1):1182. Epub 2018 Nov 29.

Department of Gynecology, Guangdong Women and Children Hospital, 521 Xing Nan Road, Guangzhou, 511400, Guangdong Province, China.

Background: To explore the diagnostic value of FAM19A4 methylation in high-risk human papilloma virus (hrHPV)-positive cervical samples from Chinese women for estimating cervical cancer or its precancerous lesions.

Methods: Cervical samples from 215 women infected with high-risk HPV were collected by smear testing. We purposely chose 61 patients with cervical cancer, 57 with high-grade squamous intraepithelial lesions (HSIL), 31 with low-grade squamous intraepithelial lesions (LSIL), and 66 without cervical intraepithelial neoplasia (CIN) after histological confirmation. Read More

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http://dx.doi.org/10.1186/s12885-018-4877-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263049PMC
November 2018
2 Reads

Evaluation of Anal Cytology in Women with History of Abnormal Pap Smear, Cervical Intraepithelial Neoplasia, Cervical Cancer and High Risk HPV for Anogenital Dysplasia

Asian Pac J Cancer Prev 2018 Nov 29;19(11):3071-3075. Epub 2018 Nov 29.

Preventative Gynecology Research Center, ShahidBeheshti University of Medical Sciences, Tehran, Iran. Email:

Background: Anal cancer is uncommon. Although uncommon, the incidence of anal cancer has increased among the general population of the United States and other countries over the past 30 years. We evaluated anal cytology in women with the history of abnormal pap smear, cervical intraepithelial neoplasia, cervical cancer and high risk HPV for anogenital dysplasia. Read More

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http://dx.doi.org/10.31557/APJCP.2018.19.11.3071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318392PMC
November 2018
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Implication of violence against women on not performing the cytopathologic test.

Rev Saude Publica 2018 Nov 23;52:89. Epub 2018 Nov 23.

Universidade Federal de Pelotas. Departamento de Nutrição. Programa de Pós-Graduação em Epidemiologia. Pelotas, RS, Brasil.

Objective: To analyze the association between intimate partner violence and not performing the cytopathologic test in the last three years.

Methods: It is a transversal study, performed in 26 health units in the city of Vitória, state Espírito Santo, from march to September 2014. The sample was constituted by 106 primary care female users, aging from 30 to 59 years-old. Read More

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http://dx.doi.org/10.11606/S1518-8787.2018052000496DOI Listing
November 2018
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Route of hysterectomy: a retrospective, cohort study in English NHS Hospitals from 2011 to 2017.

BJOG 2019 May 30;126(6):795-802. Epub 2018 Dec 30.

Department of Gynaecology, Poole Hospital, Dorset, UK.

Objective: To assess variation in the route of hysterectomy over 7 years and to assess regional variation in practice.

Design: Retrospective cohort study.

Setting: English NHS Hospitals 2011-2017. Read More

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http://dx.doi.org/10.1111/1471-0528.15539DOI Listing
May 2019
2 Reads

Laterally extended endopelvic resection with nephrectomy for vaginal cancer.

Gynecol Oncol 2019 01 16;152(1):218-219. Epub 2018 Nov 16.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2018.11.003DOI Listing
January 2019
3 Reads

Non-performance of Pap smears among pregnant women in the Extreme South of Brazil: prevalence and associated factors.

Cien Saude Colet 2018 Nov;23(11):3557-3566

Programa de Pós-Graduação em Saúde Pública, Faculdade de Medicina, FURG. Rio Grande RS Brasil.

Cervical cancer is the third most common cause of cancer among women worldwide, and Pap smears are the best screening strategy for its detection. This study evaluated the prevalence and the associated factors of the non-performance of Pap smears among pregnant women above the age of 25 during prenatal care in the municipality of Rio Grande, Brazil, in 2013. The multivariate analysis was performed by Poisson regression evaluated by prevalence ratio (PR). Read More

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http://dx.doi.org/10.1590/1413-812320182311.35162016DOI Listing
November 2018

Labour & delivery monitoring patterns in facility births across five districts of India: A cross-sectional observational study.

Indian J Med Res 2018 Sep;148(3):309-316

Independant Consultant.

Background & Objectives: India has recorded a marked increase in facility births due to government's conditional cash benefit scheme initiated in 2005. However, concerns have been raised regarding the need for improvement in the quality of care at facilities. Here we report the monitoring patterns during labour and delivery documented by direct observation in reference to the government's evidence-based guidelines on skilled birth attendance in five districts of India. Read More

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http://www.ijmr.org.in/text.asp?2018/148/3/309/245281
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http://dx.doi.org/10.4103/ijmr.IJMR_103_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251267PMC
September 2018
22 Reads

An atypical presentation of an ovarian lymphoma: a case report.

J Med Case Rep 2018 Nov 14;12(1):338. Epub 2018 Nov 14.

Department of Obstetrics & Gynaecology, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.

Background: Ovarian lymphoma has a varied clinical presentation and rarely presents with heavy menstrual bleeding. It may occur de novo or secondary to systemic disease and macroscopically appear as solid ovarian tumors.

Case Presentation: A 32-year-old Tamil woman presented with heavy menstrual bleeding of 4 months' duration. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13256-018-1884-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234537PMC
November 2018
11 Reads

Methods of Screening for Cervical Cancer-Reply.

Authors:
L Stewart Massad

JAMA 2018 11;320(18):1939

Department of Obstetrics and Gynecology, Washington University School of Medicine in St Louis, St Louis, Missouri.

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http://dx.doi.org/10.1001/jama.2018.13943DOI Listing
November 2018
1 Read

Methods of Screening for Cervical Cancer.

JAMA 2018 11;320(18):1938-1939

School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1001/jama.2018.13939DOI Listing
November 2018
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Importance of Colposcopy Impression in the Early Diagnosis of Posthysterectomy Vaginal Cancer.

J Low Genit Tract Dis 2019 Jan;23(1):13-17

Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

Objective: The aim of the study was to investigate the value of cytology, high-risk human papillomavirus (hrHPV) status and colposcopy in the early diagnosis of vaginal cancer after hysterectomy.

Materials And Methods: A retrospective study was performed in the Obstetrics and Gynecology Hospital of Fudan University. Posthysterectomy patients who were diagnosed with vaginal high-grade intraepithelial lesion (HSIL) by colposcopy-directed biopsy with colposcopy impression of extensive HSIL or suspicion of cancer and underwent upper or total vaginectomy from January 2009 to December 2017 were included. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325769PMC
January 2019
23 Reads

Safety and feasibility of contained uterine morcellation in women undergoing laparoscopic hysterectomy.

Gynecol Oncol Res Pract 2018 30;5. Epub 2018 Oct 30.

3Division of Gynecology Oncology, Department of Obstetrics and Gynecology, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710 USA.

Background: Widespread concerns have been raised regarding the safety of power morcellation of uterine specimens because of the potential to disseminate occult malignancy. We sought to assess the safety and feasibility of contained manual uterine morcellation within a plastic specimen bag among women with uterine neoplasms.

Methods: A retrospective single-institution descriptive cohort study was conducted from 2003 to 2014. Read More

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https://gynoncrp.biomedcentral.com/articles/10.1186/s40661-0
Publisher Site
http://dx.doi.org/10.1186/s40661-018-0065-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208173PMC
October 2018
19 Reads