2,875 results match your criteria Surgical Treatment of Tremor


Outcomes in Lesion Surgery versus Deep Brain Stimulation in Patients with Tremor: A Systematic Review and Meta-analysis.

World Neurosurg 2018 Nov 27. Epub 2018 Nov 27.

Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Introduction: Optimal surgical strategy for patients with tremor remains uncertain. We conducted a systematic review and meta-analysis evaluating randomized controlled trials of deep brain stimulation (DBS) and lesion surgery (LS) in treatment of tremor.

Methods: We searched PubMed, Embase and the Cochrane database to include randomized clinical trials with either lesion surgery, deep brain stimulation, or controls. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.175DOI Listing
November 2018

New Radiological Findings of Hypertrophic Olivary Degeneration in Two Patients with Brainstem Lymphoma.

World Neurosurg 2018 Nov 26. Epub 2018 Nov 26.

Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.

Background: Hypertrophic olivary degeneration (HOD) is a rare neurological condition of trans-synaptic degeneration caused by disruption of the dentatorubro-olivary pathway. We present new radiological findings of HOD in two cases of brainstem lymphoma.

Case Description: A 35-year-old woman (Case 1) and a 69-year-old man (Case 2) presented with remarkably similar clinical courses as follows. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.161DOI Listing
November 2018

MRI-guided laser interstitial thermal thalamotomy for medically intractable tremor disorders.

Mov Disord 2018 Nov 19. Epub 2018 Nov 19.

Tri-State Neurosurgery, Willis Knighton Health System, Shreveport, Louisiana, USA.

Introduction: Medically intractable tremors are a common, difficult clinical situation. Deep brain stimulation decreases Parkinson's disease resting tremor and essential tremor, but not all patients are candidates from a diagnostic, medical, or social standpoint, prompting the need for alternative surgical strategies.

Methods: We describe 13 patients with medically intractable tremor treated with laser interstitial thermal thalamotomy performed under general anesthesia using live MRI-guidance and the Clearpoint stereotactic system. Read More

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http://doi.wiley.com/10.1002/mds.27545
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http://dx.doi.org/10.1002/mds.27545DOI Listing
November 2018
5 Reads

Lithium treatment in bipolar adolescents: a follow-up naturalistic study.

Neuropsychiatr Dis Treat 2018 17;14:2749-2753. Epub 2018 Oct 17.

Clinic of Child and Adolescent Neuropsychiatry, Department of Medicine and Surgery, University of Salerno, Salerno, Italy.

Background: Although lithium is currently approved for the treatment of bipolar disorders in youth, long term data, are still scant. The aim of this study was to describe the safety and efficacy of lithium in referred bipolar adolescents, who were followed up at the 4th (T1) and 8th (T2) month of treatment.

Methods: The design was naturalistic and retrospective, based on a clinical database, including 30 patients (18 males, mean age 14. Read More

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https://www.dovepress.com/lithium-treatment-in-bipolar-adole
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http://dx.doi.org/10.2147/NDT.S172654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200433PMC
October 2018
10 Reads

Globus Pallidum DBS for Task-Specific Dystonia in a Professional Golfer.

Tremor Other Hyperkinet Mov (N Y) 2018 9;8:487. Epub 2018 Oct 9.

Department of Neurology, University of Florida, Center for Movement Disorders and Neurorestoration, Gainesville, FL, USA.

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http://www.tremorjournal.org/index.php/tremor/article/view/4
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http://dx.doi.org/10.7916/D83X9Q9DDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214811PMC
December 2018
4 Reads

Upper Limb Intention Tremor in Multiple Sclerosis: An Evidence-Based Review of Assessment and Treatment.

Int J MS Care 2018 Sep-Oct;20(5):211-223

Background: To present the current knowledge on the characteristics, assessment, and treatment of upper limb intention tremor to inform and improve future intervention studies in patients with multiple sclerosis (MS), we conducted a literature review for articles on upper limb intention tremor in patients with MS.

Methods: Two reviewers conducted searches in PubMed, Web of Science, and MEDLINE (Ovid). Relevant articles, sorted on inclusion criteria, were examined for descriptions and assessments of upper limb intention tremor, and intervention studies were evaluated based on treatment type. Read More

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http://ijmsc.org/doi/10.7224/1537-2073.2017-024
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http://dx.doi.org/10.7224/1537-2073.2017-024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200118PMC
October 2018
5 Reads

Development of a Remote-Controlled Implantable Rat Sacral Nerve Stimulation System.

Neuromodulation 2018 Oct 22. Epub 2018 Oct 22.

Nutrition, Gut & Brain Unit (INSERM U1073), Institute for Biomedical Research and innovation, Rouen University, Rouen, France.

Objectives: Sacral nerve stimulation (SNS) is a surgical treatment of urinary and fecal incontinence. Despite its clinical efficacy, the mechanisms of action of SNS are still poorly known. This may be related to the use of acute stimulation models. Read More

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http://doi.wiley.com/10.1111/ner.12870
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http://dx.doi.org/10.1111/ner.12870DOI Listing
October 2018
5 Reads

[Hardware- software complex for the differential diagnosis and evaluation of the effictiveness of treatment of extrapyramidal diseases].

Authors:
O E Khutorskaya

Zh Nevrol Psikhiatr Im S S Korsakova 2018 ;118(6. Vyp. 2):99-104

Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, Russia.

The hardware-software system of differential diagnosis and evaluation of the efficacy of treatment of a number of extrapyramidal diseases (Parkinson's disease, essential tremor, idiopathic cervical dystonia) is based on the methodology of special processing of the electrical activity of muscles (EMG). The system defines the diagnosis for each investigated muscle, and determine various forms of extrapyramidal diseases including early preclinical ones. The system allows viewing the dynamics of changes in the patient's state, both in numerical characteristics and in the graphic interpretation, and evaluates the efficacy of various forms of treatment (medicament, surgical, etc. Read More

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http://dx.doi.org/10.17116/jnevro201811806299DOI Listing
January 2018
1 Read

Deep brain stimulation of the ventralis intermedius nucleus of the thalamus and posterior subthalamic area for Holmes' tremor secondary to brainstem hemorrhage: A case report.

J Clin Neurosci 2018 Oct 16. Epub 2018 Oct 16.

Department of Neurosurgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea; Kangwon National University College of Medicine, Chuncheon, Republic of Korea. Electronic address:

Holmes' tremor is a rare but severely disabling movement disorder characterized by a combination of resting, action, and intention tremor. Because Holmes' tremor is usually resistant to pharmacotherapy, surgical treatment is required for symptom control in most cases. We report the case of a 56-year-old man who was diagnosed with Holmes' tremor and treated with stimulation of the ventralis intermedius nucleus of the thalamus and posterior subthalamic area. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.10.041DOI Listing
October 2018

Outcomes from stereotactic surgery for essential tremor.

J Neurol Neurosurg Psychiatry 2018 Oct 18. Epub 2018 Oct 18.

Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.

There are several different surgical procedures that are used to treat essential tremor (ET), including deep brain stimulation (DBS) and thalamotomy procedures with radiofrequency (RF), radiosurgery (RS) and most recently, focused ultrasound (FUS). Choosing a surgical treatment requires a careful presentation and discussion of the benefits and drawbacks of each. We conducted a literature review to compare the attributes and make an appraisal of these various procedures. Read More

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http://dx.doi.org/10.1136/jnnp-2018-318240DOI Listing
October 2018
6.807 Impact Factor

Work-Related Musculoskeletal Discomfort and Injury in Microsurgeons.

J Reconstr Microsurg 2018 Oct 16. Epub 2018 Oct 16.

Division of Plastic and Reconstructive Surgery, Mayo Clinic, Phoenix, Arizona.

Background:  Long surgical procedures with loupe magnification and microscopes may put microsurgeons at an increased risk of musculoskeletal discomfort. Identifying the prevalence and impact of work-related musculoskeletal discomfort may guide preventive strategies to prolong well-being, job satisfaction, and career duration.

Methods:  An online 29-question survey was designed to evaluate work-related musculoskeletal discomfort. Read More

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https://www.researchgate.net/profile/Sherise_Epstein/publica
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http://www.ajog.org/article/S0002937816303465/pdf
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http://downloads.hindawi.com/journals/prm/2017/5757108.pdf
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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675177
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http://dx.doi.org/10.1055/s-0038-1675177DOI Listing
October 2018
4 Reads

[Limb-shaking transitory ischaemic attack in a patient with subocclusion of the internal carotid artery].

Angiol Sosud Khir 2018;24(3):152-156

Federal Centre of Cardiovascular Surgery under the RF Ministry of Public Health, Astrakhan, Russia; Astrakhan State Medical University of the RF Ministry of Public Health, Astrakhan, Russia.

Described in the article is a clinical case report concerning symptomatic subocclusion of the internal carotid artery in a male patient with a rare variant of recurrent limb-shaking transitory ischaemic attacks (LS-TIA). The patient presented with a three-month history of episodes of involuntary jerky movements in his left hand. These episodes occurred invariably on assuming a vertical position. Read More

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December 2018
1 Read

Focused Ultrasound Thalamotomy and Other Interventions for Medication-Refractory Essential Tremor: An Indirect Comparison of Short-Term Impact on Health-Related Quality of Life.

Value Health 2018 10 28;21(10):1168-1175. Epub 2018 Jun 28.

InSightec Ltd., Tirat Carmel, Israel.

Background: Up to 50% of essential tremor patients are refractory to medication and require alternative treatment to achieve tremor relief. This study aimed to identify and analyze evidence supporting the use of the emerging magnetic resonance-guided focused ultrasound (MRgFUS) compared to alternative stimulatory and ablative interventions for the treatment of medication-refractory essential tremor: radiofrequency thalamotomy, unilateral deep brain stimulation (DBS), and stereotactic radiosurgery.

Methods: A systematic literature review was conducted to identify clinical, health-related quality of life (HRQoL), and economic evidence for each intervention. Read More

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http://dx.doi.org/10.1016/j.jval.2018.03.015DOI Listing
October 2018
1 Read

Integrating Brain Implants With Local and Distributed Computing Devices: A Next Generation Epilepsy Management System.

IEEE J Transl Eng Health Med 2018 26;6:2500112. Epub 2018 Sep 26.

Mayo Systems Electrophysiology LaboratoryDepartment of NeurologyMayo ClinicRochesterMN55905USA.

Brain stimulation has emerged as an effective treatment for a wide range of neurological and psychiatric diseases. Parkinson's disease, epilepsy, and essential tremor have FDA indications for electrical brain stimulation using intracranially implanted electrodes. Interfacing implantable brain devices with local and cloud computing resources have the potential to improve electrical stimulation efficacy, disease tracking, and management. Read More

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https://ieeexplore.ieee.org/document/8458201/
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http://dx.doi.org/10.1109/JTEHM.2018.2869398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170139PMC
September 2018
2 Reads

Robotic surgery in pediatric urology: Current status.

Asian J Endosc Surg 2018 Nov 27;11(4):308-317. Epub 2018 Sep 27.

Department of Pediatric Urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Robot-assisted laparoscopic surgery (RALS) has been increasingly embraced in the fields of adult and pediatric urology, especially in North America and Europe. The advantages of a stable magnified 3-D view, tremor filtering, and motion scaling allow for precise intracorporeal exposure and suturing. Because most surgeries are performed as reconstructive rather than excision procedures, the robotic platform is particularly feasible for the field of pediatric urology. Read More

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http://dx.doi.org/10.1111/ases.12653DOI Listing
November 2018
1 Read

Resolution of unilateral upper limb action tremor after surgical treatment of a contralateral frontoparietal arachnoid cyst.

Neurol Sci 2018 Sep 19. Epub 2018 Sep 19.

Neurology Unit, L. Sacco University Hospital, Via G.B. Grassi, 74, 20157, Milan, Italy.

Purpose: Arachnoid cysts (ACs) are cerebrospinal fluid-filled sacs. Although ACs are a frequent finding on neuroimaging, most remain asymptomatic during lifetime.

Case Report: We report a very rare case of a 62-year-old female patient presenting with a tremor due to a giant arachnoid cyst, which completely resolved after cyst-peritoneal shunting. Read More

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http://dx.doi.org/10.1007/s10072-018-3559-zDOI Listing
September 2018
1 Read

Surgical treatments for tremors.

Authors:
T Witjas-Slucki

Rev Neurol (Paris) 2018 Nov 14;174(9):615-620. Epub 2018 Sep 14.

Service de neurologie et pathologie du mouvement, UMR 7289 CNRS Aix-Marseille université, institut de neurosciences de la Timone, CHU Timone, Marseille, boulevard, Jean-Moulin, 13005 Marseille, France. Electronic address:

Stereotactic surgery is an increasingly popular option for disabling tremors whenever it is insufficiently improved by drug treatment. Surgical approaches are expanding. Thalamic deep brain stimulation is one of the most efficacious treatments. Read More

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http://dx.doi.org/10.1016/j.neurol.2018.07.004DOI Listing
November 2018

[SURGICAL TREATMENT OF PARKINSON'S DISEASE WITH LEVODOPA-INDUCED MOVEMENT DISTURBANCES].

Georgian Med News 2018 Jul-Aug(280-281):11-16

SI "Institute of Neurosurgery named after acad. A. P. Romodanov of the NAMS of Ukraine", Kyiv, Ukraine.

Aim - to evaluate the efficacy of stereotactic pallidotomy and bilateral deep brain stimulation (DBS) of subthalamic nuclei (STN) in patients with Parkinson disease with motor fluctuations and levodopa-induced dyskinesias. 36 patients (age range 31-73 years (mean age 56.2±3. Read More

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September 2018

Orthostatic Tremor is Responsive to Bilateral Thalamic Deep Brain Stimulation: Report of Two Cases Performed Asleep.

Tremor Other Hyperkinet Mov (N Y) 2018 27;8:566. Epub 2018 Jul 27.

Barrow Neurological Institute, Phoenix, AZ, USA.

Background: Orthostatic tremor (OT) is a hyperkinetic movement disorder characterized by rapid tremor in the lower extremities or trunk upon standing.

Case Report: We report two patients presenting with OT, whose symptoms improved markedly following asleep bilateral thalamic deep brain stimulation (DBS) surgery.

Discussion: Medically refractory OT can respond favorably to asleep bilateral DBS surgery similar to awake surgery, and may have the advantages of less psychological trauma to the patient, shorter procedure times, and less exposure to anesthesia. Read More

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http://dx.doi.org/10.7916/D8KS882GDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125736PMC
November 2018
5 Reads

Holmes Tremor Partially Responsive to Topiramate: A Case Report.

Tremor Other Hyperkinet Mov (N Y) 2018 26;8:565. Epub 2018 Jun 26.

Instituto Neurociencias Buenos Aires (INEBA), Departamento de Neurología - área de movimientos anormales, Buenos Aires, Argentina.

Background: Holmes tremor is a rare symptomatic movement disorder, characterized by a combination of resting, postural, and intention tremor. It is usually caused by lesions in the brainstem, thalamus, and cerebellum. Despite pharmacological advances, its treatment remains a challenge; many medications have been used with various degrees of effectiveness. Read More

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http://dx.doi.org/10.7916/D82C0FFNDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123836PMC
November 2018
8 Reads

STN vs. GPi deep brain stimulation for tremor suppression in Parkinson disease: A systematic review and meta-analysis.

Parkinsonism Relat Disord 2018 Aug 28. Epub 2018 Aug 28.

Department of Neurology, Center for Movement Disorders and Neurorestoration, University of Florida College of Medicine, Gainesville, FL, USA. Electronic address:

Objective: To compare subthalamic nucleus (STN) deep brain stimulation (DBS) with globus pallidus interna (GPi) DBS for tremor suppression in Parkinson disease (PD).

Background: DBS is an effective surgical therapy that has been shown to provide significant benefit for motor symptoms in PD. Currently, two main structures targeted to treat motor complications in PD are the STN and GPi. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2018.08.017DOI Listing
August 2018
1 Read

The long-term efficacy of STN vs GPi deep brain stimulation for Parkinson disease: A meta-analysis.

Medicine (Baltimore) 2018 Aug;97(35):e12153

Department of Neurosurgery.

Objective: This meta-analysis assessed the long-term efficacy of deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus interna (GPi) for Parkinson disease (PD).

Methods: PubMed, Cochrane Library, and Clinical Trials databases were searched. Outcomes were unified Parkinson disease rating scale section (UPDRS) III off-medication score, Parkinson's disease questionnaire: 39 activities of daily living (PDQ-39 ADL) score, and levodopa-equivalent dosage after DBS. Read More

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http://Insights.ovid.com/crossref?an=00005792-201808310-0009
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http://dx.doi.org/10.1097/MD.0000000000012153DOI Listing
August 2018
3 Reads

Parkinsonian signs in patients with cervical dystonia treated with pallidal deep brain stimulation.

Brain 2018 Oct;141(10):3023-3034

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK.

Pallidal deep brain stimulation is an established treatment in patients with dystonia. However, evidence from case series or uncontrolled studies suggests that it may lead in some patients to specific parkinsonian symptoms such as freezing of gait, micrographia, and bradykinesia. We investigated parkinsonian signs using the Movement Disorder Society Unified Parkinson's Disease Rating Scale motor score by means of observer-blinded video ratings in a group of 29 patients treated with pallidal stimulation and a non-surgical control group of 22 patients, both with predominant cervical dystonia. Read More

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http://dx.doi.org/10.1093/brain/awy217DOI Listing
October 2018
4 Reads

Experience Reduces Surgical and Hardware-Related Complications of Deep Brain Stimulation Surgery: A Single-Center Study of 181 Patients Operated in Six Years.

Parkinsons Dis 2018 22;2018:3056018. Epub 2018 Jul 22.

Department of Neurosurgery, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey.

Objective: Deep brain stimulation (DBS) surgery has increasingly been performed for the treatment of movement disorders and is associated with a wide array of complications. We aimed to present our experience and discuss strategies to minimize adverse events in light of this contemporary series and others in the literature.

Methods: A retrospective chart review was conducted to collect data on age, sex, indication, operation date, surgical technique, and perioperative and late complications. Read More

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http://dx.doi.org/10.1155/2018/3056018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081564PMC

Perioperative Care During Deep Brain Stimulation Surgery.

AORN J 2018 Aug;108(2):148-153

Deep brain stimulation (DBS) is a life-changing surgical treatment. More than 150,000 patients worldwide have been treated with DBS, primarily for Parkinson disease and medically refractory tremor and dystonia. However, the use of DBS has recently expanded beyond traditional movement disorders to include the treatment of obsessive compulsive disorder, epilepsy, and other neurological and psychological diseases. Read More

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http://dx.doi.org/10.1002/aorn.12305DOI Listing
August 2018
3 Reads

Deep Brain Stimulation in Moroccan Patients With Parkinson's Disease: The Experience of Neurology Department of Rabat.

Front Neurol 2018 31;9:532. Epub 2018 Jul 31.

Research Team in Neurology and Neurogenetics, Department of Neurology B and Neurogenetics, Faculty of Medicine and Pharmacy, Hôpital des Spécialités ONO, University Mohammed V, Rabat, Morocco.

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is known as a therapy of choice of advanced Parkinson's disease. The present study aimed to assess the beneficial and side effects of STN DBS in Moroccan Parkinsonian patients. Thirty five patients underwent bilateral STN DBS from 2008 to 2016 in the Rabat University Hospital. Read More

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http://dx.doi.org/10.3389/fneur.2018.00532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080137PMC
July 2018
15 Reads

Current surgical treatments for Parkinson's disease and potential therapeutic targets.

Neural Regen Res 2018 Aug;13(8):1342-1345

Division of Neurosurgery, Toronto Western Hospital, Department of Surgery, University of Toronto, Toronto, Canada.

Currently, the most common surgical treatment for Parkinson's disease is deep brain stimulation (DBS). This treatment strategy is typically reserved for bradykinesia, rigidity and tremor in patients who no longer respond to medication in a predictable manner or who suffer medication-induced dyskinesias. In addition to DBS, ablative procedures like radiofrequency, radiosurgery and focused ultrasound are also utilized for select tremor symptoms. Read More

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http://dx.doi.org/10.4103/1673-5374.235220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108190PMC
August 2018
0.234 Impact Factor

Predicting lesion size by accumulated thermal dose in MR-guided focused ultrasound for essential tremor.

Med Phys 2018 Oct 31;45(10):4704-4710. Epub 2018 Aug 31.

Physical Sciences, Sunnybrook Research Institute, 2075, Bayview Avenue, Toronto, ON M4N 3M5, Canada.

Purpose: To correlate the accumulated thermal dose (ATD) with lesion size in magnetic resonance (MR)-guided focused ultrasound (MRgFUS) thalamotomy to help guide future clinical treatments.

Materials And Methods: Thirty-six patients with medication-refractory essential tremor were treated using a commercial MRgFUS brain system (ExAblate 4000, InSightec) in a 3T MR scanner (MR750, GE Healthcare). Intraoperative MR-thermometry was performed to measure the induced temperature and thermal dose distributions (thermal coefficient = -0. Read More

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http://doi.wiley.com/10.1002/mp.13126
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http://dx.doi.org/10.1002/mp.13126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181766PMC
October 2018
9 Reads
2.635 Impact Factor

Intraoperative Stereotactic Magnetic Resonance Imaging for Deep Brain Stimulation Electrode Planning in Patients with Movement Disorders.

World Neurosurg 2018 Nov 8;119:e801-e808. Epub 2018 Aug 8.

Department of Neurosurgery, University Hospital Heidelberg, Germany.

Objective: Implantation of deep brain stimulation (DBS) electrodes requires stereotactic imaging. Stereotactic magnetic resonance imaging (MRI) for DBS surgery has become more popular and intraoperative MRI scanners have become more available. We report on our cohort of movement disorder patients who underwent intraoperative stereotactic MRI-only DBS electrode implantation. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.270DOI Listing
November 2018
7 Reads

Robotic versus laparoscopic gastrectomy with lymph node dissection for gastric cancer: study protocol for a randomized controlled trial.

Trials 2018 Jul 31;19(1):409. Epub 2018 Jul 31.

Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.

Background: Laparoscopic gastrectomy (LG) has several benefits as a treatment of gastric cancer (GC), including reduced pain, early recovery of intestinal function, and shorter hospital stay. LG still has several drawbacks, however, including limited range of movement, amplification of hand tremors, and inconvenient surgical positioning. Around the peripancreatic area, laparoscopic lymph node dissection, therefore, remains challenging; postoperative pancreatic fistula occurs in around 4-7% of patients undergoing LG. Read More

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http://dx.doi.org/10.1186/s13063-018-2810-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069719PMC
July 2018
3 Reads

Decisions about deep brain stimulation therapy in Parkinson's disease.

Arq Neuropsiquiatr 2018 Jun;76(6):411-420

University of Toronto, Toronto Western Hospital, Movement Disorders Centre, University Health Network, Toronto, Canada.

Parkinson's disease can be treated surgically in patients who present with motor complications such as fluctuations and dyskinesias, or medically-refractory disabling tremor. In this review, a group of specialists formulated suggestions for a preoperative evaluation protocol after reviewing the literature published up to October 2017. In this protocol, eligibility and ineligibility criteria for surgical treatment were suggested, as well as procedures that should be carried out before the multidisciplinary therapeutic decisions. Read More

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http://dx.doi.org/10.1590/0004-282X20180048DOI Listing
June 2018
2 Reads

Deep Brain Stimulation Management of Essential Tremor with Dystonic Features.

Tremor Other Hyperkinet Mov (N Y) 2018 20;8:557. Epub 2018 Jun 20.

Fixel Center for Neurological Diseases, Program for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, Gainesville, FL, USA.

Clinical Vignette: A 64-year-old female with essential tremor (ET) presents for evaluation of deep brain stimulation (DBS) candidacy. Examination revealed subtle dystonic features as well as a disabling postural-action tremor.

Clinical Dilemma: Can dystonia occur in the setting of the diagnosis of ET and can its presence alter DBS target selection?

Clinical Solution: Unilateral DBS implantation of the ventralis intermedius (Vim) led to improvement in both tremor and dystonic posturing. Read More

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http://dx.doi.org/10.7916/D8P85VBQDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026276PMC
November 2018
8 Reads

[A 36-year-old woman with primary central nervous system lymphoma diagnosed by twice brain biopsies, showing relapsing and remitting brain lesions].

Rinsho Shinkeigaku 2018 Jul 30;58(7):440-444. Epub 2018 Jun 30.

Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine.

A 36-year-old woman visited a local hospital suffering from acute onset dizziness. Brain MRI revealed multiple white matter lesions without gadolinium enhancement in the both hemispheres. Although she began to receive a treatment under a clinical diagnosis of multiple sclerosis, she developed newly emerging brain lesions and was referred to our hospital. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001145DOI Listing
July 2018
3 Reads

Spontaneous Regression of an Intraparenchymal Cyst Following Deep Brain Stimulator Electrode Implantation: Case Report and Literature Review.

World Neurosurg 2018 Sep 22;117:249-254. Epub 2018 Jun 22.

Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada.

Background: The development of an intraparenchymal cyst following deep brain stimulation (DBS) surgery is an uncommon complication that lacks a clearly defined management strategy. The pathophysiology is not known and may be related to perielectrode edema or cerebrospinal fluid tracking. Previous case reports have described various therapies for symptomatic cysts, including hardware removal or conservative treatment with steroids. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.115DOI Listing
September 2018

Pretherapeutic Motor Thalamus Resting-State Functional Connectivity with Visual Areas Predicts Tremor Arrest After Thalamotomy for Essential Tremor: Tracing the Cerebello-thalamo-visuo-motor Network.

World Neurosurg 2018 Sep 18;117:e438-e449. Epub 2018 Jun 18.

Faculty of Medicine, University of Geneva, Geneva, Switzerland; Medical Image Processing Laboratory, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Background: Essential tremor (ET) is a common movement disorder. Resting-state functional magnetic resonance imaging is a noninvasive neuroimaging method acquired in absence of task.

Objective: Our study aimed to correlate pretherapeutic ventrolateral thalamus functional connectivity (FC) with clinical results 1 year after stereotactic radiosurgical thalamotomy (SRS-T) for drug-resistant ET. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.049DOI Listing
September 2018
5 Reads

Stereotactic Selective Thalamotomy for Focal Dystonia with Aid of Depth Microrecording.

World Neurosurg 2018 Sep 14;117:e349-e361. Epub 2018 Jun 14.

Department of Neurosurgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.

Objective: Long-term effectiveness of selective ventralis intermedius nucleus (VIM)-ventralis oralis nucleus (VO) thalamotomy with depth microrecording for the treatment of focal dystonia was evaluated. The optimal thalamic areas for controlling focal dystonia were studied based on the electrophysiologic and anatomic data.

Methods: Stereotactic selective VIM-VO thalamotomy with depth microrecording was carried out in 8 patients with focal arm and hand dystonia and in 1 patient with cervical dystonia. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.033DOI Listing
September 2018

Rates, causes, risk factors, and outcomes of readmission following deep brain stimulation for movement disorders: Analysis of the U.S. Nationwide Readmissions Database.

Clin Neurol Neurosurg 2018 Aug 10;171:129-134. Epub 2018 Jun 10.

Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS, USA. Electronic address:

Objective: Deep brain stimulation (DBS) surgery has proven benefit for several movement disorders and medically-refractory psychiatric conditions and is considered a fairly safe procedure. We sought to determine the national rates, causes, predictors, and outcomes associated with 30-day and 90-day readmission.

Patients And Methods: The Nationwide Readmissions Database was queried (January-September 2013) using ICD-9-CM codes, identifying patients who underwent DBS for movement disorder (Parkinson's disease [PD], essential tremor [ET], or dystonia). Read More

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http://dx.doi.org/10.1016/j.clineuro.2018.06.013DOI Listing
August 2018
7 Reads

Objective predictors of 'early tolerance' to ventral intermediate nucleus of thalamus deep brain stimulation in essential tremor patients.

Clin Neurophysiol 2018 Aug 5;129(8):1628-1633. Epub 2018 Jun 5.

Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA. Electronic address:

Objective: To identify pre-operative clinical and computerized spiral analysis characteristics that may help ascertain which patients with Essential Tremor (ET) will exhibit 'early tolerance' to ventral intermediate nucleus of thalamus (Vim) deep brain stimulation (DBS).

Methods: Identification of comparative characteristics of defined cases of 'early tolerance' versus patients with sustained satisfactory response treated with Vim DBS surgery for medically-refractory ET, based on retrospective chart review by a clinician blinded to the findings of computerized spiral analysis.

Results: Statistically significant differences in two spiral analysis indices, SWVI and DoS, were found in the dominant upper limbs of patients who developed 'early tolerance', whereas the clinical characteristics were not significantly different. Read More

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http://dx.doi.org/10.1016/j.clinph.2018.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077991PMC
August 2018
15 Reads

Essential tremor and the cerebellum.

Authors:
Elan D Louis

Handb Clin Neurol 2018 ;155:245-258

Department of Neurology and Center for Neuroepidemiology and Clinical Neurological Research, Yale School of Medicine, Yale University, New Haven, CT, United States; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, CT, United States. Electronic address:

Essential tremor (ET) is a progressive and highly prevalent neurologic disease. Along with the tremors, mild to moderate gait ataxia and other signs of cerebellar dysfunction may occur (i.e. Read More

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https://linkinghub.elsevier.com/retrieve/pii/B97804446418920
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http://dx.doi.org/10.1016/B978-0-444-64189-2.00016-0DOI Listing
October 2018
1 Read

Robotic Nipple-Sparing Mastectomy with Immediate Prosthetic Breast Reconstruction: Surgical Technique.

Plast Reconstr Surg 2018 Sep;142(3):624-627

Villejuif, France From the Department of Plastic Surgery, Gustave Roussy.

Robotic nipple-sparing mastectomy could be a significant advancement in the treatment and prophylaxis of selected breast cancers. Motion-scaling, high-resolution, three-dimensional optics; tremor elimination; and instruments with enhanced precision with 7 degrees of freedom have allowed surgeons to overcome the limitations experienced with the endoscopic approach in breast surgery. Advantages of this procedure, in comparison with the open technique, are a shorter and more acceptable scar located in the lateral thoracic region, and greater respect for the vascularization of the mastectomy skin flap, because there is no incision on the breast and no retractors are used. Read More

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http://dx.doi.org/10.1097/PRS.0000000000004703DOI Listing
September 2018
2 Reads

Magnetic Resonance-Guided Focused Ultrasound Neurosurgery for Essential Tremor: A Health Technology Assessment.

Authors:

Ont Health Technol Assess Ser 2018 3;18(4):1-141. Epub 2018 May 3.

Background: The standard treatment option for medication-refractory essential tremor is invasive neurosurgery. A new, noninvasive alternative is magnetic resonance-guided focused ultrasound (MRgFUS) neurosurgery. We aimed to determine the effectiveness, safety, and cost-effectiveness of MRgFUS neurosurgery for the treatment of moderate to severe, medication-refractory essential tremor in Ontario. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963668PMC
October 2018

Tremor induced by Calcineurin inhibitor immunosuppression: a single-centre observational study in kidney transplanted patients.

J Neurol 2018 Jul 18;265(7):1676-1683. Epub 2018 May 18.

Section of Neurology, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Piazzale L.a. Scuro 10, 37134, Verona, Italy.

Introduction: Tremor is the most frequent and disabling neurological side effect under Calcineurin inhibitor-induced immunosuppression, but no studies have defined its phenomenology, severity, distribution, the impact on quality of life, as well as of other neurological symptoms associated.

Methods: 126 consecutive kidney-transplanted patients, under treatment with Cyclosporin A, Tacrolimus and non-Calcineurin inhibitors, within therapeutic range, were enrolled. Participants underwent a deep neurological examination by two blinded to the treatment raters, and a blood sampling to assess plasmatic immunosuppressant level and nephrological function tests. Read More

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http://dx.doi.org/10.1007/s00415-018-8904-xDOI Listing

The reduction in treatment efficiency at high acoustic powers during MR-guided transcranial focused ultrasound thalamotomy for Essential Tremor.

Med Phys 2018 Jul 1;45(7):2925-2936. Epub 2018 Jun 1.

Department of Medical Biophysics, University of Toronto, 101 College St, Room 15-701, Toronto, Canada.

Purpose: To analyze clinical data indicating a reduction in the induced energy-temperature efficiency relationship during transcranial focused ultrasound (FUS) Essential Tremor (ET) thalamotomy treatments at higher acoustic powers, establish its relationship with the spatial distribution of the focal temperature elevation, and explore its cause.

Methods: A retrospective observational study of patients (n = 19) treated between July 2015 and August 2016 for (ET) by FUS thalamotomy was performed. These data were analyzed to compare the relationships between the applied power, the applied energy, the resultant peak temperature achieved in the brain, and the dispersion of the focal volume. Read More

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http://dx.doi.org/10.1002/mp.12975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041137PMC
July 2018
7 Reads

Informed Consent Decision-Making in Deep Brain Stimulation.

Brain Sci 2018 May 11;8(5). Epub 2018 May 11.

Department of Human Neurosciences (Former Department of Neurology and Psychiatry), "Sapienza" University of Rome, 00185 Rome, Italy.

Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious. Initial evidence of DBS efficacy exists for refractory obsessive-compulsive disorder, treatment-resistant major depressive disorder, and impulse control disorders. Ethical concerns have been raised about the use of an invasive surgical approach involving the central nervous system in patients with possible impairment in cognitive functioning and decision-making capacity. Read More

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http://dx.doi.org/10.3390/brainsci8050084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977075PMC
May 2018
3 Reads

Essential Tremor.

N Engl J Med 2018 May;378(19):1802-1810

From the Clinical Trials Unit, Office of the Clinical Director (D.H.), and the Human Motor Control Section, Medical Neurology Branch (M.H.), National Institute of Neurological Disorders and Stroke Intramural Research Program, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1056/NEJMcp1707928DOI Listing

Low mood, visual hallucinations, and falls - heralding the onset of rapidly progressive probable sporadic Creutzfeldt-Jakob disease in a 73-year old: a case report.

J Med Case Rep 2018 May 8;12(1):128. Epub 2018 May 8.

Chelsea and Westminster Hospitals NHS Foundation Trust, West Middlesex University Hospital, Twickenham Rd, Isleworth, TW7 6AF, UK.

Background: Creutzfeldt-Jakob disease is a rare and rapidly fatal neurodegenerative disease. Since clinicians may see only very few cases during their professional career, it is important to be familiar with the clinical presentation and progression, to perform appropriate investigations, and allow for quick diagnosis.

Case Presentation: A 73-year-old British Caucasian woman presented with acute confusion of 2 weeks' duration on a background of low mood following a recent bereavement. Read More

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http://dx.doi.org/10.1186/s13256-018-1649-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938807PMC
May 2018
3 Reads

Structural and functional connectivity of the nondecussating dentato-rubro-thalamic tract.

Neuroimage 2018 Aug 4;176:364-371. Epub 2018 May 4.

Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

The dentato-rubro-thalamic tract (DRTT) regulates motor control, connecting the cerebellum to the thalamus. This tract is modulated by deep-brain stimulation in the surgical treatment of medically refractory tremor, especially in essential tremor, where high-frequency stimulation of the thalamus can improve symptoms. The DRTT is classically described as a decussating pathway, ascending to the contralateral thalamus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10538119183039
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http://dx.doi.org/10.1016/j.neuroimage.2018.04.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002752PMC
August 2018
8 Reads

Robotic Approach in Benign and Malignant Esophageal Tumors; A Preliminary Seven Case Series.

Chirurgia (Bucur) 2018 Mar-Apr;113(2):202-209

Esophageal surgery has been recognized as very challenging for surgeons and risky for patients. Thoracoscopic approach have proved its benefit in esophageal surgery but has some drawbacks as tremor and limited degrees of freedom, contra-intuitive movements and fulcrum effect of the surgical tools. Robotic technology has been developed with the intent to overcome these limitations of the standard laparoscopy or thoracoscopy. Read More

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http://dx.doi.org/10.21614/chirurgia.113.2.202DOI Listing
July 2018
3 Reads

Efficacy of Dural Sealant System for Preventing Brain Shift and Improving Accuracy in Deep Brain Stimulation Surgery.

Neurol Med Chir (Tokyo) 2018 May 1;58(5):199-205. Epub 2018 May 1.

Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

The success of deep brain stimulation (DBS) depends heavily on surgical accuracy, and brain shift is recognized as a significant factor influencing accuracy. We investigated the factors associated with surgical accuracy and showed the effectiveness of a dural sealant system for preventing brain shift in 32 consecutive cases receiving DBS. Thirty-two patients receiving DBS between March 2014 and May 2015 were included in this study. Read More

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http://dx.doi.org/10.2176/nmc.oa.2017-0242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958041PMC

Tacrolimus-induced parkinsonism in a patient after liver transplantation - case report.

BMC Neurol 2018 Apr 20;18(1):44. Epub 2018 Apr 20.

Second Department of Neurology, Comenius University, Limbova 5, 833 05, Bratislava, Slovakia.

Background: Hepatic encephalopathy may manifest by a wide spectrum of neuropsychiatric symptoms, including cognitive impairment, seizures or extrapyramidal symptoms. The liver transplant can lead to improvement of the signs of encephalopathy but subsequent immunosuppressive treatment might possess pronounced neurotoxicity.

Case Presentation: We present a case report of a patient with chronic liver disease who developed signs of Parkinsonism after an orthotopic liver transplant, with consecutive immunosuppressant treatment with tacrolimus. Read More

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http://dx.doi.org/10.1186/s12883-018-1052-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909232PMC
April 2018
1 Read