1,645 results match your criteria Surgical Infections[Journal]


Changes in Microbial Profiles and Antibiotic Resistance Patterns in Patients with Biliary Tract Infection Over a Six-Year Period.

Surg Infect (Larchmt) 2019 Apr 24. Epub 2019 Apr 24.

3 Department of Laboratory Medicine, School of Medicine of Shaoxing University, Shaoxing, Zhejiang, China.

Biliary tract infection (BTI) is a common complication in patients with biliary obstruction caused by various biliary tract disorders. To improve the management of patients with BTI, microbial profiles from bile cultures and antibiotic resistance patterns were evaluated in this six-year retrospective study. A total of 709 patients with various biliary tract disorders from January 2012 to December 2017 were enrolled in this study. Read More

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http://dx.doi.org/10.1089/sur.2019.041DOI Listing

Increased Incidence of Central Venous Catheter-Related Infection in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-Peritoneal Chemotherapy.

Surg Infect (Larchmt) 2019 Apr 23. Epub 2019 Apr 23.

1 National Centre for Peritoneal Malignancy, Mater Misericordiae University Hospital, Dublin, Ireland.

Cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy (HIPEC) is a complex surgical intervention with associated risks. Central venous catheter (CVC) line sepsis is one of a number of potential morbidities. The aim of this study was to calculate the incidence of catheter-related infection (CRI) in a CRS and HIPEC patient population and to assess its influence on length of hospital stay. Read More

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http://dx.doi.org/10.1089/sur.2018.250DOI Listing

Effect of Triclosan-Coated Suture on Surgical Site Infection of Abdominal Fascial Closures.

Surg Infect (Larchmt) 2019 Apr 20. Epub 2019 Apr 20.

2 Department of General Surgery, Mersin University Faculty of Medicine, Mersin, Turkey.

Surgical site infections (SSIs) are a serious problem after abdominal surgery. This study aimed to compare closure of fascia with triclosan-coated monofilament polydioxanone (PDS) or standard PDS in decreasing the incidence of SSIs in patients who underwent abdominal surgery. In this randomized study, a total of 890 consecutive patients undergoing laparotomy for any gastrointestinal pathology were allocated to closure of the fascia with triclosan-coated PDS (treatment group; TG) or standard PDS (control group; CG). Read More

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http://dx.doi.org/10.1089/sur.2019.052DOI Listing

Risk Factors and Outcomes for Sepsis after Appendectomy in Adults.

Surg Infect (Larchmt) 2019 Apr 20. Epub 2019 Apr 20.

Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Sepsis is an uncommon occurrence after appendectomy, but the morbidity and mortality of patients who develop sepsis after appendectomy remains exceedingly high. The purpose of this study is to identify risk factors and adverse post-operative outcomes associated with sepsis after appendectomy in adults. The American College of Surgery National Surgical Quality Improvement Program participant user database was queried from 2012 to 2015. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2019.003
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http://dx.doi.org/10.1089/sur.2019.003DOI Listing
April 2019
2 Reads

Risk Factors for Post-Operative Sepsis and Septic Shock in Patients Undergoing Emergency Surgery.

Surg Infect (Larchmt) 2019 Apr 5. Epub 2019 Apr 5.

4 Department of Division of Trauma, Burns, Acute Care Surgery, and Surgical Critical Care, University of California, Irvine, Orange, California.

Background: Sepsis after emergency surgery is associated with a higher mortality rate than elective surgery, and total hospital costs increase by 2.3 times. This study aimed to identify risk factors for post-operative sepsis or septic shock in patients undergoing emergency surgery. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.186
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http://dx.doi.org/10.1089/sur.2018.186DOI Listing
April 2019
8 Reads

Clinical Presentations and Outcomes of Post-Operative Central Nervous System Infection Caused by Multi-Drug-Resistant/Extensively Drug-Resistant Acinetobacter baumannii: A Retrospective Study.

Surg Infect (Larchmt) 2019 Apr 3. Epub 2019 Apr 3.

Department of Neurosurgery, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou City, China.

Background: Post-operative central nervous system infection (PCNSI) caused by multi-drug-resistant/extensively drug-resistant (MDR/XDR) Acinetobacter baumannii is a severe complication. This study aimed to analyze the clinical presentation and treatment of this disorder.

Patients And Methods: A retrospective study that recruited patients having PCNSI caused by MDR/XDR Acinetobacter baumannii was performed at our institute. Read More

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http://dx.doi.org/10.1089/sur.2018.286DOI Listing

Are Patients with Perforated Peptic Ulcers Who are Negative for Helicobacter pylori at a Greater Risk?

Surg Infect (Larchmt) 2019 Apr 2. Epub 2019 Apr 2.

1 Department of Surgery, Washington University in Saint Louis, Saint Louis, Missouri.

Background: The link between Helicobacter pylori infection and peptic ulceration is well established. Recent studies have reported a decrease of H. pylori-related peptic ulcer disease; Helicobacter pylori eradication is likely the cause of this decrease. Read More

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http://dx.doi.org/10.1089/sur.2018.249DOI Listing
April 2019
6 Reads

Retrospective Analysis of Post-Operative Antibiotics in Complicated Appendicitis.

Surg Infect (Larchmt) 2019 Mar 30. Epub 2019 Mar 30.

1 Department of Surgery, Boston University School of Medicine, Boston, Massachusetts.

Background: There is no consensus regarding the ideal post-operative antibiotic strategy for surgically managed complicated appendicitis. The goal of this study was to investigate different antibiotic regimens used for this purpose at our institution and their association with post-operative outcomes.

Methods: The 1,102 patients underwent appendectomy from 2012 to 2016. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.223
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http://dx.doi.org/10.1089/sur.2018.223DOI Listing
March 2019
7 Reads

In Vitro Assessment of Microbial Barrier Properties of Cyanoacrylate Tissue Adhesives and Pressure-Sensitive Adhesives.

Surg Infect (Larchmt) 2019 Mar 30. Epub 2019 Mar 30.

1 Division of Infectious Diseases, University of Kansas Health System, Kansas City, Kansas.

Background: Despite advances in incision care and surgical dressings, surgical site infections remain a common complication. Post-operative contamination of a surgical site is believed to play a role in many of these infections. Most surgical dressings adhere to the skin with pressure-sensitive adhesives. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.280
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http://dx.doi.org/10.1089/sur.2018.280DOI Listing
March 2019
3 Reads

Complicated Disease Course in Initially Computed Tomography-Proven Uncomplicated Acute Diverticulitis.

Surg Infect (Larchmt) 2019 Mar 30. Epub 2019 Mar 30.

3 Department of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.

Background: Although uncomplicated acute diverticulitis has a benign disease course, some patients are at increased risk for complications. Identification of these patients may aid the selection of treatment strategies such as outpatient treatment. This study aimed to assess the rate and timing of a complicated disease course in initially computed tomography (CT)-proven uncomplicated diverticulitis, and to identify risk factors for the development of these diverticular complications. Read More

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http://dx.doi.org/10.1089/sur.2018.289DOI Listing
March 2019
1 Read

Shenfu Injection Attenuates Bile Duct Injury in Rats with Acute Obstructive Cholangitis.

Surg Infect (Larchmt) 2019 Mar 29. Epub 2019 Mar 29.

Department of Hepatobliliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.

Background: We investigated the effect of Shenfu injection (SFI) in Wistar rats with acute obstructive cholangitis (AOC) and considered the possible molecular mechanisms of the effects.

Methods: The 96 rats were divided randomly into three groups. In one group, the common bile duct was subjected to ligation (BDL), and 0. Read More

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http://dx.doi.org/10.1089/sur.2018.304DOI Listing
March 2019
1 Read

Reactivation of Latent Cytomegalovirus Infection after Major Surgery: Risk Factors and Outcomes.

Surg Infect (Larchmt) 2019 Mar 26. Epub 2019 Mar 26.

1 Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts.

Background: Reactivation of latent cytomegalovirus (CMV) infection occurs in previously immunocompetent critically ill individuals and may be associated with increased morbidity and mortality. Our aim was to explore risk factors for and outcomes after CMV reactivation in patients undergoing major surgery.

Patients And Methods: We performed a retrospective case control study of patients without underlying immunocompromise who developed post-operative CMV reactivation from 2004-2016. Read More

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http://dx.doi.org/10.1089/sur.2018.245DOI Listing
March 2019
1 Read

Evaluation of Rectal Vancomycin Irrigation for Treatment of Clostridioides difficile Infection in Patients Post-Colectomy for Toxic Colitis.

Surg Infect (Larchmt) 2019 Mar 22. Epub 2019 Mar 22.

2 Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background: Clostridioides difficile infection (CDI) accounts for as many as 25% of episodes of antibiotic-associated diarrhea and is the most common cause of healthcare-associated diarrhea. Rectal vancomycin irrigation is a therapy option; however, evidence is limited for its value post-colectomy. The objective of this study was to describe outcomes of patients who underwent total colectomy for fulminant C. Read More

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http://dx.doi.org/10.1089/sur.2018.265DOI Listing

The Heroin Epidemic in America: A Surgeon's Perspective.

Surg Infect (Larchmt) 2019 Mar 22. Epub 2019 Mar 22.

5 Division of Acute Care Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan.

Background: The United States is currently experiencing a heroin epidemic. Recent reports have demonstrated a three-fold increase in heroin use among Americans since 2007 with a shift in demographics to more women and white Americans. Furthermore, there has been a correlation between the recent opioid epidemic and an increase in heroin abuse. Read More

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http://dx.doi.org/10.1089/sur.2019.004DOI Listing
March 2019
2 Reads

Gender Disparity in Surgery: An Evaluation of Surgical Societies.

Surg Infect (Larchmt) 2019 Mar 20. Epub 2019 Mar 20.

4 Surgical Infection Society, East Northport, New York.

Background: The percentage of female surgeons and surgery residents has increased slowly to 24% and 35%, respectively. However, women remain under-represented in surgical leadership positions (<20%). Society awards and leadership positions are used for hiring and promoting surgeons. Read More

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http://dx.doi.org/10.1089/sur.2018.220DOI Listing
March 2019
1 Read

Comparative Effectiveness of Ceftriaxone plus Metronidazole versus Anti-Pseudomonal Antibiotics for Perforated Appendicitis in Children.

Surg Infect (Larchmt) 2019 Mar 15. Epub 2019 Mar 15.

2 Department of Pediatrics and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Background: Appendicitis is the most common pediatric surgical emergency and one of the most common indications for antibiotic use in hospitalized children. The antibiotic choice differs widely across children's hospitals, and the optimal regimen for perforated appendicitis remains unclear.

Methods: We conducted a retrospective cohort study comparing initial antibiotic regimens for perforated appendicitis at a large tertiary-care children's hospital. Read More

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http://dx.doi.org/10.1089/sur.2018.234DOI Listing
March 2019
1 Read

Commonly Encountered Skin Biome-Derived Pathogens after Orthopedic Surgery.

Surg Infect (Larchmt) 2019 Mar 6. Epub 2019 Mar 6.

Department of Orthopaedic Surgery, Warren Alpert Medical School of Brown University, Providence, Rhode Island.

Background: Normal skin microbiota influence susceptibility to surgical infections. The distribution of skin bacteria differs by anatomic site, and given the right conditions, almost any of these bacteria can become an opportunistic pathogen.

Methods: This paper provides a thorough review of the most commonly encountered bacteria in various regions of the body and their isolation from operative incisions at those locations. Read More

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http://dx.doi.org/10.1089/sur.2018.161DOI Listing

Use of Topical Antibiotics before Primary Incision Closure to Prevent Surgical Site Infection: A Meta-Analysis.

Surg Infect (Larchmt) 2019 Mar 6. Epub 2019 Mar 6.

3 DPhil Programme in Evidence-Based Healthcare, University of Oxford, Oxford, United Kingdom.

Background: Surgical site infections (SSIs) remains a concern for surgeons because of the negative impact on outcomes and health care costs. Our purpose was to assess whether topical antibiotics before primary incision closure reduced the rate of SSIs.

Methods: Systematic review of MEDLINE/PubMed, Scopus, CINAHL, and Web of Science databases from inception to January 2017. Read More

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http://dx.doi.org/10.1089/sur.2018.279DOI Listing
March 2019
1 Read

Surgical Site Infection in Endometriosis Surgery Is a Rare Complication: Results of a Single Center's Prospective Surveillance of Eight Hundred Ninety-Six Procedures.

Surg Infect (Larchmt) 2019 Feb 28. Epub 2019 Feb 28.

1 Department of Epidemiology and Public Health, Rouen University Hospital, Rouen, France.

Background: There are no studies reporting the rate of surgical site infection (SSI) after surgery for endometriosis, although this information is valuable when discussing the most appropriate treatment strategy with the patient.

Methods: We conducted a prospective cohort study in a university hospital and regional reference center for endometriosis. We sought to measure the rate of SSI after endometriosis surgery using prospective SSI post-discharge surveillance data and the hospital information system via an ad hoc algorithm using both diagnosis and procedure code classifications. Read More

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http://dx.doi.org/10.1089/sur.2018.209DOI Listing
February 2019
3 Reads

Clinical Outcome and Risk Factors for Emergency Department Adult Patients with Thoracic Empyema after Video-Assisted Thoracic Surgical Procedure.

Surg Infect (Larchmt) 2019 Feb 27. Epub 2019 Feb 27.

1 Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taiwan, R.O.C.

Background: Empyema is a purulent infection of the pleural cavity that is most relevant to parapneumonia effusion. Video-assisted thoracoscopic surgery (VATS) is an option for stage 2 (fibrinopurulent) and stage 3 (organizational). Surgeons may see critically ill patients with pleural empyema who present to the emergency department (ED). Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.239
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http://dx.doi.org/10.1089/sur.2018.239DOI Listing
February 2019
8 Reads

Two-Layer Wound Sealing before Surgical Hand Washing for Surgeons with a Minor Cut Injury on the Hand.

Surg Infect (Larchmt) 2019 Feb 27. Epub 2019 Feb 27.

4 Department of Orthopedic Surgery, Seoul National University Hospital, Seoul, Korea.

Background: There is a lack of evidence-based recommendations for surgical hand washing when there is a minor cut on the hand. We sought to evaluate whether two-layer wound sealing functions as a barrier to prevent the spread of micro-organisms.

Methods: We randomly categorized 20 surgeons into subjects with either a right- or left-hand injury. Read More

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http://dx.doi.org/10.1089/sur.2018.271DOI Listing
February 2019

The Paradox of Hyperglycemia and Surgical Outcomes in Patients with and without Diabetes.

Surg Infect (Larchmt) 2019 Feb 26. Epub 2019 Feb 26.

3 Department of Surgery, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1089/sur.2018.270DOI Listing
February 2019

Decreasing Trend of Surgical Site Infections among Surgical Patients in a University Hospital in Thailand after an Active Surveillance Program.

Surg Infect (Larchmt) 2019 Feb 25. Epub 2019 Feb 25.

3 Infection Control Unit, Songklanagarind Hospital, Hat Yai, Songkhla, Thailand.

Background: Reports from high-quality healthcare systems have shown that active surveillance and management of factors associated with surgical site infection (SSI) decreased the incidence and improved overall outcomes.

Methods: This study aimed to appraise the incidence trend of SSIs during the 10-year period between 2007 and 2016 in a university hospital in a middle-income country, focusing on six high-risk and high-volume procedures. The study also examined factors associated with SSIs and their impact on surgical outcomes. Read More

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http://dx.doi.org/10.1089/sur.2018.124DOI Listing
February 2019
1 Read

Efficacy of Antibiotic Agents after Spill of Bile and Gallstones during Laparoscopic Cholecystectomy.

Surg Infect (Larchmt) 2019 Feb 22. Epub 2019 Feb 22.

1 Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.

Background: Perforation of the gallbladder during laparoscopic cholecystectomy (LC) results in spill of bile or gallstones in the abdominal cavity. The aim of this study was to assess whether antibiotic agents after spill have an effect on post-operative and infectious complications.

Patients And Methods: Operative reports and clinical data of patients undergoing LC between 2012 and 2016 in three hospitals were screened retrospectively for spill of bile and spill of gallstones. Read More

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http://dx.doi.org/10.1089/sur.2018.195DOI Listing
February 2019
2 Reads

Measuring and Improving the Design Quality of Operating Rooms.

Surg Infect (Larchmt) 2019 Feb/Mar;20(2):102-106

2 HOK Architects, St. Louis, Missouri.

Background: Existing research regarding design improvements to the operating room (OR) is scarce and emphasizes the compelling need to measure and test new design strategies and interventions.

Methods: We propose a conceptual framework for measuring and improving OR physical space design by outlining how two existing measurement schemes can be adapted for ORs. The structure, process, outcomes model described by Donabedian in 1966 is used to show how each of these three measurement approaches can be used to evaluate OR design. Read More

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http://dx.doi.org/10.1089/sur.2018.291DOI Listing

Prevention of Surgical Infections: It's More than Antibiotics.

Authors:
Donald E Fry

Surg Infect (Larchmt) 2019 Feb/Mar;20(2):101

1 Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1089/sur.2019-29015-dfDOI Listing
February 2019

Actinomyces turicensis Necrotizing Soft-Tissue Infection of the Thigh in a Diabetic Male.

Surg Infect (Larchmt) 2019 Feb 21. Epub 2019 Feb 21.

4 Department of Pharmacy, JPS Health Network, Fort Worth, Texas.

Background: Necrotizing soft-tissue infections are a devastating infection that is rarely caused by Actinomyces spp.

Case Report: A 45-year-old obese previously healthy male presented to the emergency department with diabetic ketoacidosis. The patient developed systemic signs of infections and right medial thigh pain subsequently diagnosed as a necrotizing soft-tissue infection. Read More

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http://dx.doi.org/10.1089/sur.2018.149DOI Listing
February 2019
2 Reads

Meropenem and Amikacin for Management of Post-Neurosurgical Infections from Acinetobacter baumannii.

Surg Infect (Larchmt) 2019 Feb 20. Epub 2019 Feb 20.

Department of Critical Care Medicine, Suizhou Hospital Affiliated to Hubei Medical College, Hubei, China.

Background: Intra-cranial infection with Acinetobacter baumannii is a tough problem because of the presence of multi-resistance and poor drug penetration through the blood-brain barrier. Such intra-cranial infections can lead to serious complications and death. We retrospectively analyzed the culture results and clinical characteristics of patients with intra-cranial infections in our hospital and suggested intravenous (IV) meropenem and intra-thecal (IT) amikacin therapy may be effective in the management of A. Read More

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http://dx.doi.org/10.1089/sur.2018.242DOI Listing
February 2019
1 Read

Cellulose-Derived Absorbable Hemostatic Product as a Risk Factor for Mediastinitis after Cardiac Surgery.

Surg Infect (Larchmt) 2019 Feb 20. Epub 2019 Feb 20.

1 Preventive Medicine Department and Infectious Disease Unit, Puerta de Hierro Majadahonda University Hospital, Majadahonda, Madrid, Spain.

Background: We describe the management and control of an outbreak of mediastinitis in a cardiac surgery department.

Method: We performed a retrospective cohort study of 87 patients who underwent coronary artery bypass grafting (CABG), valve replacement, or both during a five-month period with a higher than normal number of cases of post-operative mediastinitis. In addition to medical records review, a survey was conducted among surgeons to estimate the frequency of cellulose-derived absorbable hemostatic (CDAH) use. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.268
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http://dx.doi.org/10.1089/sur.2018.268DOI Listing
February 2019
14 Reads

Increased Healthcare-Associated Infections in a Surgical Intensive Care Unit Related to Boarding Non-Surgical Patients.

Surg Infect (Larchmt) 2019 Feb 15. Epub 2019 Feb 15.

3 Department of Surgery, Division of Acute Care Surgery Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey.

Background: Hospital over-capacity often forces boarding patients outside of their designated intensive care unit (ICU). Anecdotal evidence suggested medical intensive care unit (MICU) patients boarding in the surgical intensive care unit (SICU) were responsible for increases in healthcare-associated infection (HAI) rates. We studied the effect of ICU boarding on rates of SICU HAIs. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.240
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http://dx.doi.org/10.1089/sur.2018.240DOI Listing
February 2019
7 Reads

Antibiotic Prophylaxis in Pediatric Cardiac Surgery: Where Are We and Where Do We Go? A Systematic Review.

Surg Infect (Larchmt) 2019 Feb 14. Epub 2019 Feb 14.

1 Department of Pediatric Cardiothoracic Surgery and Children's Memorial Health Institute, Warsaw, Poland.

Background: Prophylactic antibiotic therapy is given routinely in the peri-operative period to prevent surgical site infection. However, in pediatric cardiac surgery, an optimal schedule has not been defined. Pediatric recommendations follow the guidelines for adults, which might be improper because of the inherent challenges in pediatric research and the heterogeneity of the population. Read More

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http://dx.doi.org/10.1089/sur.2018.272DOI Listing
February 2019
1 Read

Specific National Surveillance Program for Organ Space Infections after Colonic Surgery.

Surg Infect (Larchmt) 2019 Feb 11. Epub 2019 Feb 11.

1 Department of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.

Background: The present study aimed to analyze risk factors and management strategies for organ space infections (OSI) specifically after colonic resections.

Methods: This was a retrospective analysis of all consecutive colonic resections performed between February 2012 and October 2017 in a single-center quality-improvement project. All OSIs were assessed prospectively by an independent national surveillance program ( www. Read More

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http://dx.doi.org/10.1089/sur.2018.217DOI Listing
February 2019

Rate of Glove Perforation in Open Abdominal Surgery and the Associated Risk Factors.

Surg Infect (Larchmt) 2019 Feb 8. Epub 2019 Feb 8.

3 Faculty of Health Science, Department of Social Work, Manisa Celal Bayar University, Manisa, Turkey.

Background: Glove perforation is common during surgery. Surgical gloves are used as personal protective equipment to reduce infection risks from bloodborne pathogens for both the surgical team and patients. This research was conducted to determine the perforation rates of gloves worn in open abdominal surgery performed in a general surgery department and the risk factors affecting perforation. Read More

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http://dx.doi.org/10.1089/sur.2018.229DOI Listing
February 2019

Is the Platelet to Lymphocyte Ratio a Potential Biomarker for Predicting Mortality in Peptic Ulcer Perforation?

Surg Infect (Larchmt) 2019 Feb 8. Epub 2019 Feb 8.

Kirikkale University School of Medicine, Department of General Surgery, Kirikkale, Turkey.

Background: Despite surgical treatment of peptic ulcer perforation (PUP), the high rates of morbidity and mortality have motivated researchers to search for new laboratory markers to predict morbidity and mortality. The aim of this study was to investigate the relation between pre-operative laboratory values and demographic factors and post-operative mortality in patients undergoing surgery for PUP.

Patients And Methods: A retrospective study was made of the clinical findings and laboratory data of patients operated on for a diagnosis of PUP in the general surgery clinic between 2014 and 2018. Read More

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http://dx.doi.org/10.1089/sur.2018.288DOI Listing
February 2019
2 Reads

Polymicrobial Bacteremia Involving Klebsiella pneumoniae in Patients with Complicated Intra-Abdominal Infections: Frequency, Co-Pathogens, Risk Factors, and Clinical Outcomes.

Surg Infect (Larchmt) 2019 Feb 8. Epub 2019 Feb 8.

1 Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.

Background: Klebsiella pneumoniae has gained notoriety because of its high antibiotic resistance and mortality. We compared the clinical features and outcomes of polymicrobial bacteremia involving K. pneumoniae (PBKP). Read More

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http://dx.doi.org/10.1089/sur.2018.207DOI Listing
February 2019
5 Reads
1.721 Impact Factor

Electronically Triggered Sepsis Alert in Non-Intensive Care Inpatients Using Modified Systemic Inflammatory Response Syndrome Criteria: A Retrospective Observational Study with In-Depth Analysis of Surgical Patients.

Surg Infect (Larchmt) 2019 Feb 6. Epub 2019 Feb 6.

1 Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota.

Background: Our center initiated an electronic Sepsis Best Practice Alert (sBPA) protocol to aid in early sepsis detection and treatment. However, surgery alters peri-operative physiology, which may trigger an sBPA for noninfectious causes. This study aimed to provide early evaluation of automated sBPA utility in surgical patients. Read More

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http://dx.doi.org/10.1089/sur.2018.228DOI Listing
February 2019

Influenza and the Surgeon.

Surg Infect (Larchmt) 2019 Feb/Mar;20(2):119-128. Epub 2019 Feb 6.

Division of Surgical Research, Department of Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.

Background: The influenza virus is a pathogenic virus responsible for large numbers of deaths and long-term disabilities worldwide. Although the very young, the very old, and immunocompromised individuals are most susceptible, the effects of the influenza virus can be observed across the entire spectrum of individuals.

Discussion: Infection with the influenza virus induces a substantial inflammatory and immunologic response and induces marked pulmonary inflammation. Read More

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http://dx.doi.org/10.1089/sur.2019.015DOI Listing
March 2019
2 Reads

Does Intra-Abdominal Infection after Curative Gastrectomy Affect Patients' Long-Term Prognosis? A Multi-Center Study Based on a Large Sample Size.

Surg Infect (Larchmt) 2019 Feb 5. Epub 2019 Feb 5.

1 Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.

Background: The objective of the study was to investigate the effects of intra-abdominal infection after curative gastrectomy on the prognosis of patients.

Patients And Methods: Data were collected for enrolled patients who underwent curative gastrectomy in two centers; the relationship between intra-abdominal infection and prognosis was analyzed.

Results: Of the 5,721 patients in the entire group, intra-abdominal infection occurred in 202 (3. Read More

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http://dx.doi.org/10.1089/sur.2018.246DOI Listing
February 2019
8 Reads

Vancomycin Enema in the Treatment of Clostridium difficile Infection.

Surg Infect (Larchmt) 2019 Feb 4. Epub 2019 Feb 4.

Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan.

Background: Current guidelines for the treatment of Clostridium difficile infections (CDIs) recommend vancomycin enemas for patients with adynamic ileus. There is significant variability in guideline recommendations for vancomycin dose and enema volume and whether a retention enema should be used. The most recent (2017) guidelines from the Infectious Diseases Society of America/Society for Healthcare Epidemiology of America recommend rectal instillation of 500 mg of vancomycin in 100 mL of physiologic saline every 6 hours as a retention enema. Read More

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http://dx.doi.org/10.1089/sur.2018.238DOI Listing
February 2019
1 Read

Sweet and Sour: Impact of Early Glycemic Control on Outcomes in Necrotizing Soft-Tissue Infections.

Surg Infect (Larchmt) 2019 Feb 4. Epub 2019 Feb 4.

1 Department of Pharmacy and The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background: Necrotizing soft-tissue infection (NSTI) is a devastating disease associated with high rates of morbidity and mortality. Hyperglycemia is associated with poor wound healing; however, there are no studies evaluating glycemic control outcomes in patients with NSTI. The objective of this study was to examine disease progression and death in patients with NSTI who achieved early glycemic control (EGC) compared with patients that did not. Read More

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http://dx.doi.org/10.1089/sur.2018.182DOI Listing
February 2019
7 Reads

Does the Use of Antibiotic-Loaded Bone Cement Have an Effect on Deep Infection in Primary Total Knee Arthroplasty Practice?

Authors:
Sadullah Turhan

Surg Infect (Larchmt) 2019 Apr 1;20(3):244-246. Epub 2019 Feb 1.

Antalya Training and Research Hospital, Department of Orthopaedics and Traumatology, Antalya, Turkey.

Background: Total knee arthroplasty (TKA) is performed to improve the quality of life by reducing knee arthralgia. One of the most destructive and expensive complications of TKA is deep infection. The primary purpose of this study was to evaluate the effect of using antibiotic-loaded bone cement (ALBC) on the incidence of deep infection after primary TKA. Read More

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http://dx.doi.org/10.1089/sur.2018.123DOI Listing

CD4+ T Cell Immune Response to VP1 and VP3 in BK Virus Infected Recipients of Renal Transplantation.

Surg Infect (Larchmt) 2019 Apr 1;20(3):236-243. Epub 2019 Feb 1.

Department of Transplantation Surgery, The 309th Hospital of Chinese People's Liberation Army, Beijing, China.

Objective: To investigate the characteristics of BK virus (BKV) specific cellular immune response in the recipients who have early infection with BKV after renal transplantation.

Methods: The recipients of renal allografts (n = 30) were divided into groups of BK virus nephropathy (BKVN), viruria, and viremia. The BKV load was observed with real-time fluorescence quantitative polymerase chain reaction in urine and blood every three months. Read More

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http://dx.doi.org/10.1089/sur.2018.116DOI Listing
April 2019
1 Read

Nanometric Considerations in Biofilm Formation.

Surg Infect (Larchmt) 2019 Apr 31;20(3):167-173. Epub 2019 Jan 31.

1 Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Prosthetic contamination and biofilm formation continue to plague implanted materials. With increasing resistance to traditional antibiotic regimens, alternative approaches to preventing bacterial adhesion and biofilm formation have focused on the physiochemical properties of the prosthetics. Roughness, topography, hydrophobicity, porosity, charge, stiffness, and surface area all influence the processes of adhesion and colonization leading to biofilm formation. Read More

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http://dx.doi.org/10.1089/sur.2018.237DOI Listing
April 2019
2 Reads

Treating Surgical Infections in Low- and Middle-Income Countries: Source Control, Then What?

Authors:
Jennifer Rickard

Surg Infect (Larchmt) 2019 Apr 30;20(3):192-196. Epub 2019 Jan 30.

Department of Surgery, University of Minnesota, Minneapolis, Minnesota.

Surgical infections present a significant burden of disease globally. Management focuses on source control and appropriate antibiotic therapy. This remains a challenge in low- and middle-income settings, where access to surgical care and antibiotics is limited. Read More

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http://dx.doi.org/10.1089/sur.2018.125DOI Listing

Risk of Surgical Site Infection in Patients with Asymptomatic Bacteriuria or Abnormal Urinalysis before Joint Arthroplasty: Systematic Review and Meta-Analysis.

Surg Infect (Larchmt) 2019 Apr 28;20(3):159-166. Epub 2019 Jan 28.

1 School of Medicine, Health Sciences Faculty, Department of Surgery, Universidad Industrial de Santander, Bucaramanga, Colombia.

Background: Routine screening and treatment for pre-operative asymptomatic bacteriuria (ASB) before joint arthroplasty are controversial. This systematic review and meta-analysis aimed to evaluate the impact of ASB and other bacterial colonization markers (BCM) observed in abnormal urine analyses, such as positive nitrites, leukocyturia, or positive leukocyte esterase in the risk of surgical site infections (SSIs) of joint arthroplasty patients.

Methods: Studies published between 1970 and 2017 that reported data on SSI and prosthetic joint infection (PJI) in patients after joint arthroplasty of the hip, knee, or shoulder with pre-operative ASB or BCM were included. Read More

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http://dx.doi.org/10.1089/sur.2018.201DOI Listing
April 2019
1 Read

Key Ways to Prevent Infection When There Is No "Building": Aspects for the Field.

Authors:
David P Blake

Surg Infect (Larchmt) 2019 Feb/Mar;20(2):115-118. Epub 2019 Jan 24.

Division of Acute Care Surgery, Department of Surgery, Hartford Hospital, Hartford, Connecticut and Department of Surgery, Uniformed Services University of the Health Sciences F. Edward Hébert School of Medicine, Bethesda, Maryland.

Background: Infection control is a critical aspect in the continuum of surgical care. Much of what is outlined in the literature pertains to hospital-based practice, with only recent attention paid to the more austere environments, particularly those faced during humanitarian or combat operations.

Objective: This manuscript provides a brief historical review of the development of infection control practices and further identifies and outlines several aspects necessary to successful program applications in austere environments. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.290
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http://dx.doi.org/10.1089/sur.2018.290DOI Listing
March 2019
9 Reads

Infection Prevention: Unique Aspects of Burn Units.

Authors:
Tina L Palmieri

Surg Infect (Larchmt) 2019 Feb/Mar;20(2):111-114. Epub 2019 Jan 24.

1 Shriners Hospital for Children Northern California, Sacramento, California.

Background: Infection is a common complication of burn injury caused by the loss of skin (the primary defense against micro-organisms) as well as burn-induced immunosuppression. Essentially, survival after burn injury is determined by whether wound healing or infection predominates. The purpose of this article is to describe how burn unit structure and design may impact the incidence of infection after burn injury. Read More

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http://dx.doi.org/10.1089/sur.2018.301DOI Listing
March 2019
2 Reads

Current Evaluation of Antibiotic Usage in Complicated Intra-Abdominal Infection after the STOP IT Trial: Did We STOP IT?

Surg Infect (Larchmt) 2019 Apr 24;20(3):184-191. Epub 2019 Jan 24.

1 Department of Surgery, MetroHealth Medical Center, Cleveland, Ohio.

Background: After publication of the Study to Optimize Peritoneal Infection Therapy (STOP IT) trial, we sought to determine if we were implementing study findings into practice appropriately. We had three objectives: evaluate antibiotic usage; evaluate patient outcomes; and delineate differences in antibiotic usage between general surgeons (GS) and trauma/acute care surgery trained surgeons (TACS).

Patients And Methods: This was an analysis of patients with complicated intra-abdominal infection admitted via the emergency department from February 2014 through May 2017. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.121
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http://dx.doi.org/10.1089/sur.2018.121DOI Listing
April 2019
5 Reads

Ten-Year Experience in the Prevention of Post-Kasai Cholangitis.

Surg Infect (Larchmt) 2019 Apr 18;20(3):231-235. Epub 2019 Jan 18.

Department of General Pediatric Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Background: Cholangitis is the most common complication after the Kasai procedure. It can be life-threatening and may affect long- and short-term outcomes of children with biliary atresia. We summarize our experiences in the prevention of early-onset cholangitis. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.047
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http://dx.doi.org/10.1089/sur.2018.047DOI Listing
April 2019
5 Reads

Comparison of Surveillance of Surgical Site Infections by a National Surveillance Program and by Institutional Audit.

Surg Infect (Larchmt) 2019 Apr 18;20(3):225-230. Epub 2019 Jan 18.

2 Department of Visceral Surgery, Lausanne University Hospital CHUV, Switzerland.

Background: Reported incidence of surgical site infections (SSI) after colonic surgery varies widely. These variations depend not only on patient- and surgery-related parameters but are influenced by type and quality of follow-up. The aim of the study was to compare SSI assessed by two independent prospective surveillance systems, a national surveillance program based on recommendations of the National Healthcare Safety Network (Swissnoso) versus an international audit system, the ERAS Interactive Audit System (EIAS; Encare, Stockholm, Sweden). Read More

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http://dx.doi.org/10.1089/sur.2018.211DOI Listing
April 2019
2 Reads