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    A case of IV degree on acute radiation dermatitis in China.
    Int J Surg Case Rep 2017 Feb 2;32:19-21. Epub 2017 Feb 2.
    Department of Drug, Jilin University School of Pharmaceutical Sciences, Changchun, 130021, China. Electronic address:
    This report investigates the nursing procedure of a case of adjuvant therapy of rectal cancer on IV degree of acute radiation dermatitis patients in the penis and scrotum junction. The lesion degree gradually increased. Fixation of the dressing was difficult in the penis and scrotum junction. Read More

    A Biodegradable Hemostatic Gelatin/Polycaprolactone Composite for Surgical Hemostasis.
    Ann Plast Surg 2017 Feb 14. Epub 2017 Feb 14.
    From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center; †Institute of Polymer Science and Engineering, National Taiwan University; and ‡Department of Orthopedics, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan, Republic of China.
    Massive bleeding is the leading cause of battlefield-related deaths and the second leading cause of deaths in civilian trauma centers. One of the challenges of managing severe wounds is the need to promote hemostasis as quickly as possible, which can be achieved by using hemostatic dressings. In this study, we fabricated 2 kinds of gelatin/polycaprolactone composites with 2 ratios of gelatin/polycaprolactone, 1:1 and 2:1 (GP11 and GP21, respectively). Read More

    Prevention of postsurgical wound dehiscence after abdominal surgery with NPWT: a multicentre randomised controlled trial protocol.
    J Wound Care 2017 Feb;26(Sup2):S23-S26
    Professor of Primary Health Care and Community, School of Nursing and Midwifery, Curtin University, Perth, WA, Australia; and Wound Management Innovation Cooperative Research Centre (WMICRC); and Silver Chain Group, WA, Australia.
    Objective: The effectiveness of negative pressure wound therapy (NPWT) in the prevention of postoperative surgical wound dehiscence (SWD) is the subject of much debate and remains to be determined. This study will identify individuals at risk of postoperative SWD and trial the use of NPWT as a prophylactic measure against the occurrence of SWD, compared with a non-NPWT standard surgical dressing (SSD).

    Method: A prospective multicentre randomised controlled trial comparing NPWT dressing against standard surgical dressings (SSD) will be conducted. Read More

    Healing of an arterial leg ulcer by compression bandaging: a case report.
    J Wound Care 2017 Feb;26(Sup2):S18-S22
    Emeritus Professor, SERGAS (Service Galego of Health) LUGO/Spain.
    This case report demonstrates that arterial ulcers may heal with compression therapy. The patient was a 72-year-old woman with elevated blood pressure and type II diabetes mellitus, who underwent angiography because of a painful, non-healing ulcer over the shin. The angiography showed multisegment arterial occlusive disease, not amenable to surgical revascularisation. Read More

    [Management of lymphatic fistulas in the groin from a surgeon's perspective].
    Chirurg 2017 Feb 8. Epub 2017 Feb 8.
    Contilia Herz- und Gefäßzentrum, Klinik für Gefäßchirurgie und Phlebologie, Elisabeth-Krankenhaus Essen, Essen, Deutschland.
    Background: The postoperative occurrence of lymph fistulas in the groin is a complication that should be taken seriously. These fistulas cause an increase in morbidity and can support local and ascending infections. The treatment of this complication ranges from conservative procedures, such as compression dressings and bed rest to operative treatment with detection of the fistulas and ligation, negative pressure wound therapy (NPWT) or even muscle flaps. Read More

    On-Demand Dissolution of Chemically Cross-Linked Hydrogels.
    Acc Chem Res 2017 Feb 7. Epub 2017 Feb 7.
    Departments of Chemistry, Biomedical Engineering, and Medicine, Boston University , 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.
    The formation and subsequent on-demand dissolution of chemically cross-linked hydrogels is of keen interest to chemists, engineers, and clinicians. In this Account, we summarize our recent advances in the area of dissolvable chemically cross-linked hydrogels and provide a comparative discussion of other recent hydrogel systems. Using biocompatible macromonomers, we developed a library of cross-linked dendritic hydrogels that possess favorable properties, including biocompatibility, tissue adhesion, and swelling. Read More

    A systematic review and meta-analysis of clinical outcomes associated with nanocrystalline silver use compared to alternative silver delivery systems in the management of superficial and deep partial thickness burns.
    Burns 2017 Feb 1. Epub 2017 Feb 1.
    Department of Plastic Surgery, Kuopio University Hospital, Kuopio, Finland.
    Objective: The purpose of this systematic review and meta-analysis was to assess the clinical effectiveness of nanocrystalline silver compared to alternative silver delivery systems (silver sulphadiazine [SSD] and silver nitrate) in adults and children with superficial and deep partial thickness burns.

    Methods: PubMed, EMBASE, Cochrane and other databases were searched to identify relevant randomised controlled trials and observational studies.

    Results: Eight studies that assessed both nanocrystalline silver and SSD and one study that compared nanocrystalline silver vs. Read More

    Delayed Surgical Debridement and Use of Semiocclusive Dressings for Salvage of Fingers After Purpura Fulminans.
    Hand (N Y) 2016 Dec 3;11(4):NP34-NP37. Epub 2016 Aug 3.
    Pontificia Universidad Católica de Chile, Santiago, Chile.
    Background: Purpura fulminans is a condition characterized by rapidly evolving skin necrosis and disseminated intravascular coagulation. Early recognition and aggressive supportive management has led to a decrease in its mortality rate, but most of these patients must undergo extensive soft tissue debridement and partial or total limb amputation. There is controversial evidence about the timing of surgery, suggesting that some patients may benefit from delayed debridement with limb preservation. Read More

    Tourniquets do not increase the total blood loss or re-amputation risk in transtibial amputations.
    World J Orthop 2017 Jan 18;8(1):62-67. Epub 2017 Jan 18.
    Christian Wied, Peter T Tengberg, Gitte Holm, Thomas Kallemose, Anders Troelsen, Morten T Kristensen, Department of Orthopedic Surgery, Copenhagen University Hospital Hvidovre, 2650 Hvidovre, Denmark.
    Aim: To investigate the total blood loss (TBL) and the safety with respect to the re-amputation rate after transtibial amputation (TTA) conducted with and without a tourniquet.

    Methods: The study was a single-centre retrospective cohort study of patients with a primary TTA admitted between January 2013 and April 2015. All patients with a primary TTA were assessed for inclusion if the amputation was performed because of arteriosclerosis or diabetic complications. Read More

    Calvarial metastasis of renal cell carcinoma.
    BMJ Support Palliat Care 2017 Jan 31. Epub 2017 Jan 31.
    Service de Chirurgie Plastique, Reconstructrice et Esthétique, Hôpital Européen Georges Pompidou, Université Paris-Descartes, Paris, France.
    The calvarium is an extremely unusual site of metastasis of renal cell carcinoma. We report a 62-year-old man who was enrolled for palliative medical management for an exophytic calvarial metastasis. His quality of life was greatly compromised with everyday local care and bandages due to recurrent events of infection and bleeding, limiting his social life. Read More

    [Postoperative wound infections : Diagnosis, classification and treatment].
    Chirurg 2017 Jan 26. Epub 2017 Jan 26.
    Klinik für Allgemein- und Viszeralchirurgie, Sana-Klinikum Lichtenberg, Berlin, Deutschland.
    Background: Surgical site infections are a frequent complication of surgery and a severe burden for the patient as well as for the healthcare system. Sound knowledge of the disease pattern is an essential prerequisite for effective therapy.

    Objective: This article presents an overview of the diagnosis, classification and treatment options for surgical site infections. Read More

    A non-invasive tool for detecting cervical cancer odor by trained scent dogs.
    BMC Cancer 2017 Jan 26;17(1):79. Epub 2017 Jan 26.
    Laboratorio de Oncología Genómica, Unidad de Investigación Médica en Enfermedades Oncológicas, UMAE Hospital de Oncología, CMN- SXXI-IMSS, Av. Cuauhtémoc 330, Col. Doctores, Del. Cuauhtémoc, 06720, Mexico City, Mexico.
    Background: Cervical Cancer (CC) has become a public health concern of alarming proportions in many developing countries such as Mexico, particularly in low income sectors and marginalized regions. As such, an early detection is a key medical factor in improving not only their population's quality of life but also its life expectancy. Interestingly, there has been an increase in the number of reports describing successful attempts at detecting cancer cells in human tissues or fluids using trained (sniffer) dogs. Read More

    Economic case for intraoperative interventions to prevent surgical-site infection.
    Br J Surg 2017 Jan;104(2):e55-e64
    Centre for Applied Health Economics, School of Medicine, Menzies Health Institute of Queensland, Griffith University, Brisbane, Queensland, Australia.
    Background: Surgical-site infection (SSI) occurs in 1-10 per cent of all patients undergoing surgery; rates can be higher depending on the type of surgery. The aim of this review was to establish whether (or not) surgical hand asepsis, intraoperative skin antisepsis and selected surgical dressings are cost-effective in SSI prevention, and to examine the quality of reporting.

    Methods: The authors searched MEDLINE via Ovid, CINAHL via EBSCO, Cochrane Central and Scopus databases systematically from 1990 to 2016. Read More

    A Retrospective Comparison of the Performance of Two Negative Pressure Wound Therapy Systems in the Management of Wounds of Mixed Etiology.
    Adv Wound Care (New Rochelle) 2017 Jan;6(1):33-37
    Smith & Nephew , Hull, United Kingdom .
    Objective: Negative pressure wound therapy (NPWT) has been shown to be effective in the management of chronic and surgical wounds. The two most widely used modalities of NPWT are vacuum-assisted closure (V.A. Read More

    Examination of the early wound healing process under different wound dressing conditions.
    Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Mar 11;123(3):310-319. Epub 2016 Nov 11.
    Field of Oral and Maxillofacial Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
    Objective: Various types of wound-healing dressings have been used to assist in the healing of surgical wounds. We analyzed the wound-healing process in an animal model using different existing wound dressings.

    Study Design: Full-thickness defects were created using a biopsy punch on the backs of 7-week-old rats. Read More

    Multicenter Study of Pin Site Infections and Skin Complications Following Pinning of Pediatric Supracondylar Humerus Fractures.
    Cureus 2016 Dec 3;8(12):e911. Epub 2016 Dec 3.
    Orthopedic Surgery, Nemours Children's Hospital.
    Introduction: Pediatric supracondylar humerus fractures are the most common elbow fractures in pediatric patients. Surgical fixation using pins is the primary treatment for displaced fractures. Pin site infections may follow supracondylar humerus fracture fixation; the previously reported incidence rate in the literature is 2. Read More

    Development of Advanced Dressings for the Delivery of Progenitor Cells.
    ACS Appl Mater Interfaces 2017 Feb 19;9(4):3445-3454. Epub 2017 Jan 19.
    Cooperative Research Centre for Cell Therapy Manufacturing , North Terrace, Adelaide, South Australia 5000, Australia.
    Culture surfaces that substantially reduce the degree of cell manipulation in the delivery of cell sheets to patients are described. These surfaces support the attachment, culture, and delivery of multipotent adult progenitor cells (MAPC). It was essential that the processes of attachment/detachment to the surface did not affect cell phenotype nor the function of the cultured cells. Read More

    Ultrashort self-assembling Fmoc-peptide gelators for anti-infective biomaterial applications.
    J Pept Sci 2017 Feb 9;23(2):131-140. Epub 2017 Jan 9.
    Biofunctional Nanomaterials Group, School of Pharmacy, Medical Biology Centre, Queen's University Belfast, 97 Lisburn Rd, Belfast, N. Ireland, BT9 7BL, UK.
    Biomaterial-related infections have a significant impact on society and are a major contributor to the growing threat of antimicrobial resistance. Current licensed antibiotic classes struggle to breakdown or penetrate the exopolysaccharide biofilm barrier, resulting in sub-therapeutic concentrations of antibiotic at the surface of the biomaterial, treatment failure and increased spread of resistant isolates. This paper focuses for the first time on the ability of ultrashort Fmoc-peptide gelators to eradicate established bacterial biofilms implicated in a variety of medical device infections (Gram-positive: Staphylococcus aureus, Staphylococcus epidermidis and Gram-negative Escherichia coli, Pseudomonas aeruginosa). Read More

    Resolving Epibole With Polymeric Membrane Dressings in Home Care.
    J Wound Ostomy Continence Nurs 2017 Jan/Feb;44(1):89-92
    Kimberly S. Bare, BSN, RN, CWON, Amedisys, Baton Rouge, Louisiana. Jerri Drain, BSN, RN, CWON, Amedisys, Baton Rouge, Louisiana.
    Background: The management of chronic (nonhealing) wounds with epibole is challenging and costly, especially when the problem is not promptly identified or the patient is intolerant to conventional treatments.

    Case Description: We describe the use of a polymeric membrane dressing (PMD) in 3 patients with chronic (nonhealing) wounds and epibole who were unable to be treated with traditional interventions such as silver nitrate or sharp debridement. Patient 1 was a 51 year-old male with a right foot stasis ulcer with 60% fibrin/slough to the wound bed, patient 2 was a 58-year-old female with a stage 4 pressure injury of the left hip with undermining, and patient 3 was a 62-year-old female with a dehisced abdominal surgical wound. Read More

    A survey of patients with surgical wounds healing by secondary intention; an assessment of prevalence, aetiology, duration and management.
    J Tissue Viability 2016 Dec 21. Epub 2016 Dec 21.
    School of Nursing, Midwifery and Social Work, The University of Manchester, Manchester, UK.
    Background: Surgical wounds healing by secondary intention (SWHSI) are often difficult and costly to treat. There is a dearth of clinical and research information regarding SWHSI. The aim of this survey was to estimate the prevalence of SWHSI and to characterise the aetiology, duration and management of these wounds. Read More

    Negative pressure wound therapy in orthopaedic surgery.
    Orthop Traumatol Surg Res 2017 Feb 30;103(1S):S99-S103. Epub 2016 Dec 30.
    Institut de chirurgie de la main de l'ouest parisien, hôpital privé de l'ouest parisien, 14, rue Castiglione del Lago, 78190 Trappes, France; Urgences mains Paris Peupliers, 8, place de l'Abbé-Georges-Hénocque, 75013 Paris, France. Electronic address:
    Negative pressure wound therapy (NPWT) consists in applying subatmospheric pressure to a wound that is sealed off by a specially designed dressing and connected by a tube to a suction pump and drainage collection system. Skin defects are extremely common in orthopaedic and trauma surgery. NPWT is valuable across a range of indications. Read More

    Factors predicting venous thromboembolism after spine surgery.
    Medicine (Baltimore) 2016 Dec;95(52):e5776
    aDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang bJizhong Energy Fengfeng Group General Hospital, Handan Shi, Hebei Province cHebei Provincial Key Laboratory of Orthopedic Biomechanics, Shijiazhuang, China.
    Background: A meta-analysis was performed to explore predicted factors of venous thromboembolism (VTE) after surgery in the treatment for spine degeneration diseases.

    Summary Of Background Data: Many scholars have focused on VTE after spine surgery, but as for the risk factors of VTE have not reached a consensus.

    Methods: An extensive search of literature, "spine or spinal," "degeneration," "after surgery or postoperation," and "venous thromboembolism" as key words, was performed in PubMed/MEDLINE, Embase, the Cochrane library, CNKI, and WANFANG databases. Read More

    Importance of Scar Prevention and Treatment-An Approach From Wound Care Principles.
    Dermatol Surg 2017 Jan;43 Suppl 1:S85-S90
    *Medical and Scientific Director, Skin Doctors' Center Trieste, Trieste, Italy; †Department of Dermatology, University of the Orange Free State, Bloemfontein, South Africa; ‡Department of Burn, State Hospital # 3, Nikolaev, Ukraine.
    Background: The increased number of cosmetic surgical and nonsurgical procedures has led to a greater demand to achieve aesthetically acceptable scars. Silicone gel (SG) dressings were evaluated in these cases following the principles of wound care and also minimizing abnormal scar formation.

    Patients And Methods: A newly developed solution in wound care in the form of a SG has proven to be a highly effective treatment for a series of 4 clinically challenging cases presented in this article: postprocedure healing after a laser treatment, nonhealing scalp wounds, chronic relapsing xerotic eczematous cheilitis, and the treatment of scars caused by third degree burns. Read More

    Clinical Usage and Economic Effectiveness of a Recently Developed Epidermal Autograft Harvesting System in 13 Chronic Wound Patients in a University-Based Wound Center.
    Cureus 2016 Nov 14;8(11):e878. Epub 2016 Nov 14.
    Division of Acute Care Surgery, University of Missouri, Columbia, Missouri.
    Introduction:  Chronic wounds are a significant healthcare problem in the United States. Their costs approach 25 billion dollars in the United States. Current wound-care treatments of local wound care, moist dressings, and source control, while necessary for wound healing, are frequently not enough to ensure complete wound closure. Read More

    Chronic radiation-induced dermatitis: challenges and solutions.
    Clin Cosmet Investig Dermatol 2016 9;9:473-482. Epub 2016 Dec 9.
    Department of Radiotherapy I, The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.
    Chronic radiation dermatitis is a late side effect of skin irradiation, which may deteriorate patients' quality of life. There is a lack of precise data about its incidence; however, several risk factors may predispose to the development of this condition. It includes radiotherapy dose, fractionation, technique, concurrent systemic therapy, comorbidities, and personal and genetic factors. Read More

    The role of allogenic keratin - derived dressing in wound healing in a mouse model.
    Wound Repair Regen 2016 Dec 20. Epub 2016 Dec 20.
    Department of Neuropeptides, Mossakowski Medical Research Centre, Polish Academy of Sciences, 5 Pawińskiego St., 02-106, Warsaw, Poland.
    Keratin is an interesting protein needed for wound healing and tissue recovery. We have recently proposed a new, simple and inexpensive method to obtain fur and hair keratin-derived biomaterials suitable for medical application. The aim of the study was to evaluate the role of the fur keratin derived protein (FKDP) dressing in the allogenic full-thickness surgical skin wound model. Read More

    Dressings for the prevention of surgical site infection.
    Cochrane Database Syst Rev 2016 12 20;12:CD003091. Epub 2016 Dec 20.
    Bristol Centre for Surgical Research, School of Social & Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, UK, BS8 2PS.
    Background: Surgical wounds (incisions) heal by primary intention when the wound edges are brought together and secured, often with sutures, staples, or clips. Wound dressings applied after wound closure may provide physical support, protection and absorb exudate. There are many different types of wound dressings available and wounds can also be left uncovered (exposed). Read More

    Conservative interventions for treating middle third clavicle fractures in adolescents and adults.
    Cochrane Database Syst Rev 2016 12 15;12:CD007121. Epub 2016 Dec 15.
    Department of Orthopaedics and Traumatology, Universidade Federal de São Paulo, Rua Borges Lagoa, 783-5th Floor, São Paulo, São Paulo, Brazil.
    Background: Clavicle (collarbone) fractures account for around 4% of all fractures. Most (76%) clavicle fractures involve the middle-third section of the clavicle. Treatment of these fractures is usually non-surgical (conservative). Read More

    Negative pressure wound therapy aids recovery following surgical debridement due to severe bacterial cellulitis with abdominal abscess post-cesarean: A case report (CARE-Compliant).
    Medicine (Baltimore) 2016 Dec;95(50):e5397
    aDepartment of Molecular Medicine, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK. bDepartment of Obstetrics and Gynaecology, Princess Anne Hospital, Southampton, UK.
    Introduction: Bacterial cellulitis post-Cesarean section is rare. Negative pressure wound therapy (NPWT) is widely used in various medical specialities; its effectiveness in obstetrics however remains the topic of debate-used predominantly as an adjunct to secondary intention specific to high-risk patient groups. Its application in the treatment of actively infected wounds post-Cesarean is not well documented. Read More

    Epidermal Graft Accelerates the Healing of Acute Wound: A Self-controlled Case Report.
    Plast Reconstr Surg Glob Open 2016 Nov 21;4(11):e1119. Epub 2016 Nov 21.
    Royal Free Hospital Wound Healing Group, Department of Plastic and Reconstructive Surgery, Royal Free London Hospital, London, United Kingdom; and Royal Free Hospital Wound Healing Group, Department of Plastic and Reconstructive Surgery, Royal Free Hospital, London, United Kingdom.
    Wound care represents a significant socioeconomic burden, with over half of chronic wounds taking up to a year to heal. Measures to accelerate wound healing are beneficial to patients and also reduce the cost and burden of wound management. Epidermal grafting (EG) is an emerging option for autologous skin grafting in the outpatient setting to improve wound healing. Read More

    Treatment of multiple wounds of aplasia cutis congenita on the lower limb: a case report.
    J Wound Care 2016 Dec;25(12):760-762
    Plastic and Reconstructive Unit, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
    Introduction: Aplasia cutis congenita (ACC) is a rare congenital disease, characterised by absence of skin, that can affect different parts of the body. ACC is more frequent on the scalp, but can involve limbs, with partial-or total-thickness loss of skin, with a functional impairment of the joint affected. There is no clear indication for surgical or conservative treatment, therefore, it would be helpful to find scientific support for the optimal treatment strategies. Read More

    The utility of vacuum-assisted closure therapy for skin necrosis secondary to cervical abscess in the elderly.
    Auris Nasus Larynx 2016 Dec 5. Epub 2016 Dec 5.
    The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan.
    Vacuum-assisted closure (VAC) systems have been used as negative-pressure dressings in various fields, including decubitus ulcer, trauma, and wound dehiscence. To the best of our knowledge, few reports have examined the utility of VAC therapy for neck abscess in an oldest-old patient. We present here a rare case of neck abscess secondary to parotid abscess, resulting in extensive skin necrosis. Read More

    Prophylactic Negative Pressure Dressing Use in Closed Laparotomy Wounds Following Abdominal Operations: A Randomized, Controlled, Open-label Trial: The P.I.C.O. Trial.
    Ann Surg 2016 Dec 6. Epub 2016 Dec 6.
    Department of Surgery, University Hospital Limerick, Limerick, Ireland.
    Objective: A randomized controlled trial was undertaken to investigate the effect of prophylactic negative pressure dressings on postoperative surgical site infection (SSI) rates in closed laparotomy wounds.

    Summary Of Background Data: Laparotomy wounds are associated with high rates of SSI. The effect of prophylactic negative pressure dressing of closed incisional wounds on SSI rate is unknown. Read More

    Physical exercise for the treatment of non-ulcerated chronic venous insufficiency.
    Cochrane Database Syst Rev 2016 12 3;12:CD010637. Epub 2016 Dec 3.
    Department of Physiology, Federal University of Paraná, Avenida Coronel Francisco Heráclito dos Santos, 210, Jardim das Américas, Curitiba, Parana, Brazil, 81531-970.
    Background: Chronic venous insufficiency (CVI) is a common disease that causes discomfort and impairs the quality of life of affected persons. Treatments such as physical exercise that aim to increase the movement of the ankle joint and strengthen the muscle pump in the calf of the leg may be useful to reduce the symptoms of CVI.

    Objectives: To assess and summarise the existing clinical evidence on the efficacy and safety of physical exercise programmes for the treatment of individuals with non-ulcerated CVI. Read More

    Negative-pressure wound therapy for prevention and treatment of surgical-site infections after vascular surgery.
    Br J Surg 2017 Jan 30;104(2):e75-e84. Epub 2016 Nov 30.
    Department of Surgical Sciences, Vascular Surgery, Uppsala University, Uppsala, Sweden.
    Background: Indications for negative-pressure wound therapy (NPWT) in vascular surgical patients are expanding. The aim of this review was to outline the evidence for NPWT on open and closed wounds.

    Methods: A PubMed, EMBASE and Cochrane Library search from 2007 to June 2016 was performed combining the medical subject headings terms 'wound infection', 'abdominal aortic aneurysm (AAA)', 'fasciotomy', 'vascular surgery' and 'NPWT' or 'VAC'. Read More

    Devices and dressings to secure peripheral venous catheters: A Cochrane systematic review and meta-analysis.
    Int J Nurs Stud 2017 Feb 16;67:12-19. Epub 2016 Nov 16.
    Centre for Clinical Nursing, Royal Brisbane and Women's Hospital, Brisbane, Australia; AVATAR, Menzies Health Institute, Griffith University, Brisbane, Australia.
    Background: Peripheral venous catheterisation is the most frequent invasive procedure performed in hospitalised patients; yet over 30% of peripheral venous catheters fail before treatment ends.

    Objectives: To assess the effects of peripheral venous catheter dressings and securement devices on the incidence of peripheral venous catheter failure.

    Data Sources: We searched the Cochrane Wounds Group Register, The Cochrane Central Register of Controlled Trials, MEDLINE; EMBASE and CINAHL for any randomised controlled trials comparing different dressings or securement devices used to stabilise peripheral venous catheters. Read More

    Novel perspectives on the role of the human microbiota in regenerative medicine and surgery.
    Biomed Rep 2016 Nov 11;5(5):519-524. Epub 2016 Oct 11.
    Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, Plastic Surgery Unit, University of Pavia, Pavia, I-27100 Lombardy, Italy; Plastic and Reconstructive Surgery Unit, Salvatore Maugeri Research and Care Institute, Pavia, I-27100 Lombardy, Italy.
    Plastic surgery is transitioning from a fine craftsmanship to a regenerative science. In wound healing, the role of microorganisms is no longer considered to be just counteracting, but also promoting. Furthermore, host-microbe interactions are essential for numerous aspects of normal mammalian physiology, from metabolic activity to immune homeostasis. Read More

    Lesions requiring wound management in a central tertiary neonatal intensive care unit.
    World J Pediatr 2016 Nov 23. Epub 2016 Nov 23.
    Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary.
    Background: Most of the skin disorders that occur in neonatal intensive care units are due in part to the immaturity and vulnerability of the neonatal skin. Various iatrogenic diagnostic and therapeutic procedures are also conducive to iatrogenic damage. This study was to review the neonates admitted to our neonatal intensive care unit who needed wound management, and to assess the most common skin injuries and wounds, and their aetiology. Read More

    Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy.
    Adv Skin Wound Care 2016 Dec;29(12):560-566
    Background: Bites by Loxosceles spiders (also known as recluse spiders or brown spiders) can cause necrotic ulcerations of various sizes and dimensions. The current standard of care for brown spider bites includes analgesics, ice, compression, elevation, antihistamines, and surgical debridement. Hyperbaric oxygen therapy (HBOT) in the treatment of brown spider bites has been administered in the early stage of ulceration, or 2 to 6 days after the bite. Read More

    The hospital costs associated with acute paediatric burn injuries.
    S Afr Med J 2016 Nov 2;106(11):1120-1124. Epub 2016 Nov 2.
    Institute of Health Policy and Management (iBMG), Erasmus University Rotterdam, The Netherlands.
    Background: Ongoing rationing of healthcare threatens services that are well established, and cripples others that desperately require investment. Burn, for one, remains a neglected epidemic in South Africa (SA), despite the magnitude of the problem.

    Objective: To identify the prominent components contributing to the cost of hospital admission with paediatric burn injury. Read More

    Honey and larvae in the treatment of foot gangrene: a reflection.
    Br J Nurs 2016 Nov;25(20 Suppl):S10-S14
    Third Year Adult Nursing Student, University of Hertfordshire (now Staff Nurse, Barnet Hospital, Royal Free Foundation NHS Trust).
    With the introduction of the Nursing and Midwifery Council's (NMC) (2015a) revalidation directive, nurses are required to demonstrate an ongoing commitment to providing safe and effective care by continually combining sound empirical evidence with reflective practice ( Sackett et al, 1996 ; Rolfe et al, 2011 ). Using Gibbs' (1998) model, I will reflect on an episode of care undertaken while I was on a recent placement. This reflective account will discuss the clinical use of honey and larvae therapy in the treatment of foot gangrene following meningococcal septicaemia. Read More

    Primary wound closure of diabetic foot ulcers by debridement and stitching.
    J Wound Care 2016 Nov;25(11):650-654
    Professor of Surgery, FRCSI Assistant professor, Department of Surgery, Faculty of Medicine, University of Khartoum.
    Objective: The role of stitching in healing diabetic foot ulcers (DFUs) has little attention, with few reports published on the technique. This study aimed to report on the role of stitching in healing of neuropathic DFUs.

    Method: This comparative study was between patients with diabetes with neuropathic foot ulcers who had undergone wound stitching and those on conventional wound care. Read More

    Biological effects and clinical application of negative pressure wound therapy: a review.
    J Wound Care 2016 Nov;25(11):617-626
    Associated Professor Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
    Negative pressure wound therapy (NPWT) has shown great advantages in the management of a wide range of clinical problems such as wound or chronic wound healing; open wounds with exposed bone, nerve, or tendon; and orthopaedic implants and related infection in the orthopaedics field. Even though it has shown positive efficacy in treating infection (wound infection or orthopaedic implant infection), its molecular mechanisms of action remain unclear and require further exploration. Since NPWT is widely used in the clinical setting, a comprehensive understanding of its biological effect will assist in appropriate clinical application. Read More

    Negative pressure wound therapy versus usual care for Surgical Wounds Healing by Secondary Intention (SWHSI trial): study protocol for a randomised controlled pilot trial.
    Trials 2016 Nov 8;17(1):535. Epub 2016 Nov 8.
    Hull and East Yorkshire Hospitals NHS Trust, Hull, UK.
    Background: Most incisions following surgery heal by primary intention, with the edges of the wound apposed with sutures or clips. However, some wounds may break open or be left to heal from the bottom up (i.e. Read More

    Topical antibiotics for preventing surgical site infection in wounds healing by primary intention.
    Cochrane Database Syst Rev 2016 11 7;11:CD011426. Epub 2016 Nov 7.
    General Practice and Rural Medicine, James Cook University, Mackay Base Hospital, Bridge Road, Mackay, Queensland, Australia, 4740.
    Background: Surgical site infections (SSI) can delay wound healing, impair cosmetic outcome and increase healthcare costs. Topical antibiotics are sometimes used to reduce microbial contaminant exposure following surgical procedures, with the aim of reducing SSIs.

    Objectives: The primary objective of this review was to determine whether the application of topical antibiotics to surgical wounds that are healing by primary intention reduces the incidence of SSI and whether it increases the incidence of adverse outcomes (allergic contact dermatitis, infections with patterns of antibiotic resistance and anaphylaxis). Read More

    Surgical site infection in posterior spine surgery.
    Niger J Clin Pract 2016 Nov-Dec;19(6):821-826
    Department of Surgery, Neurosurgery Unit, Lagos University Teaching Hospital, Idi-Araba, Lagos State, Nigeria.
    Background: Surgical site infections (SSIs) in spine surgery remain a significant cause of morbidity and prolonged hospitalization. Factors affecting SSI includes patient's comorbidities, duration of surgery, type and indication for surgery among others. We intend to document our experience in our center and highlight possible factors influencing SSI in posterior spine surgery. Read More

    A wet dressing for male genital surgery: A phase II clinical trial.
    Int Braz J Urol 2016 Nov-Dec;42(6):1220-1227
    Serviço de Urologia do Hospital das Clínicas, Departamento de Cirurgia do Centro de Ciências da Saúde da Universidade Federal de Pernambuco, UFPE, Brasil.
    Purpose: This study was to confirm the safety and efficacy of BC dressing when used in surgical male wound healing at the urogenital area.

    Methods: Open, non-controlled clinical study of phase II. A total of 141 patients, among those children, adolescents and adults with hypospadias (112), epispadias (04), phymosis (13) and Peyronie's disease (12) that had a BC dressing applied over the operated area after surgery. Read More

    Compression versus No Compression after Endovenous Ablation of the Great Saphenous Vein: A Randomized Controlled Trial.
    Ann Vasc Surg 2017 Jan 20;38:72-77. Epub 2016 Aug 20.
    Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
    Background: The goal of this study is to determine if compression therapy after endovenous ablation (EVA) of the great saphenous vein (GSV) improves efficacy and patient-reported outcomes of pain, ecchymosis, and quality of life.

    Methods: This is a prospective randomized controlled trial from 2009 to 2013 comparing the use of thigh-high 30-40 mm Hg compression therapy for 7 days versus no compression therapy following EVA of the GSV. Severity of venous disease was measured by clinical severity, etiology, anatomy, pathophysiology scale and the Venous Clinical Severity Score (VCSS). Read More

    A 4-arm randomized controlled pilot trial of innovative solutions for jugular central venous access device securement in 221 cardiac surgical patients.
    J Crit Care 2016 Dec 21;36:35-42. Epub 2016 Jun 21.
    AVATAR Group, NHMRC Centre of Research Excellence in Nursing, Menzies Health Institute Queensland, Griffith University, Nathan, 4111, Queensland, Australia; Critical Care Research Group, The University of Queensland and The Prince Charles Hospital, Chermside, 4032, Queensland, Australia. Electronic address:
    Purpose: To improve jugular central venous access device (CVAD) securement, prevent CVAD failure (composite: dislodgement, occlusion, breakage, local or bloodstream infection), and assess subsequent trial feasibility.

    Materials And Methods: Study design was a 4-arm, parallel, randomized, controlled, nonblinded, pilot trial. Patients received CVAD securement with (i) suture+bordered polyurethane (suture + BPU; control), (ii) suture+absorbent dressing (suture + AD), (iii) sutureless securement device+simple polyurethane (SSD+SPU), or (iv) tissue adhesive+simple polyurethane (TA+SPU). Read More

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