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    1 OF 220

    In search of the optimal wound dressing material following total hip and knee arthroplasty: a systematic review and meta-analysis.
    Int Orthop 2017 May 11. Epub 2017 May 11.
    Knee Surgery and Sports Medicine, Joint Reconstruction Centre, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, Seoul, 463-707, Republic of Korea.
    Background: Various types of dressing materials are available for wound care following hip and knee arthroplasty. However, it is unclear if one material is more beneficial than the others in terms of wound complications and fluid handling capacity.

    Research Questions: We performed a meta-analysis of randomized controlled trials comparing alternative wound dressing materials for the post-operative management of wounds following THA and TKA with respect to (1) incidence of wound complications including infection and (2) fluid handling capacity. Read More

    Dialkylcarbamoyl chloride dressings in the prevention of surgical site infections following non-implant vascular surgery.
    Ann Vasc Surg 2017 May 5. Epub 2017 May 5.
    Academic Vascular Surgical Unit, Hull York Medical School, UK.
    Background: Dressings coated with Dialkylcarbamoyl chloride (DACC) are highly hydrophobic and irreversibly bind multiple types of bacteria, trapping them in the dressing and reducing the number of organisms at the wound surface. We aimed to assess the impact of DACC coated postoperative dressings on the incidence of surgical site infection (SSI) in non-implant vascular surgery patients.

    Methods: Two hundred patients undergoing non implant vascular surgery were prospectively recruited at a single vascular centre. Read More

    Role of acute negative pressure wound therapy over primarily closed surgical incisions in acetabular fracture ORIF: A prospective randomized trial.
    Injury 2017 Apr 27. Epub 2017 Apr 27.
    University of Missouri, Department of Orthopaedic Surgery, One Hospital Drive, N116, Columbia, MO, United States. Electronic address:
    Background: Negative pressure wound therapy use over closed surgical incisions (iNPWT) has proven to be effective at reducing hematoma, wound drainage and infection in high-risk wounds. The purpose of this study was to determine if iNPWT decreased the risk of infection in patients undergoing open reduction internal fixation (ORIF) for acetabular fractures.

    Methods: 71 patients who underwent operative intervention for an acetabular fracture between March 2008 and September 2012 consented and prospectively randomized to iNPWT or a standard postoperative (dry gauze) dressing. Read More

    Use of fat transfer to treat a chronic, non-healing, post-radiation ulcer: a case study.
    J Wound Care 2017 May;26(5):272-273
    Consultant Plastic and Reconstructive Surgeon.
    Objective: Problematic wound healing and ulceration in radiation-damaged tissue is a surgical challenge. Clinical studies have shown that grafting fat tissue in an irradiated area can improve the quality of the skin and has regenerative effects. This case study describes how fat transfer led to the healing of a chronic ulcer resistant to other forms of treatment. Read More

    Prehospital Interventions During Mass-Casualty Events in Afghanistan: A Case Analysis.
    Prehosp Disaster Med 2017 May 3:1-4. Epub 2017 May 3.
    4University of Texas Health Sciences Center at San Antonio,San Antonio,TexasUSA.
    Background: Mass-casualty (MASCAL) events are known to occur in the combat setting. There are very limited data at this time from the Joint Theater (Iraq and Afghanistan) wars specific to MASCAL events. The purpose of this report was to provide preliminary data for the development of prehospital planning and guidelines. Read More

    Culture-independent detection of chlorhexidine resistance genes qacA/B and smr in bacterial DNA recovered from body sites treated with chlorhexidine-containing dressings.
    J Med Microbiol 2017 Apr;66(4):447-453
    2​Alliance for Vascular Access Teaching and Research, Griffith University, Brisbane, Australia 3​Inflammation and Healing Research Cluster, School of Health and Sports Sciences, University of the Sunshine Coast, Sippy Downs, Brisbane, Australia.
    Purpose: Dressings containing chlorhexidine gluconate (CHG) are increasingly used in clinical environments for prevention of infection at central venous catheter insertion sites. Increased tolerance to this biocide in staphylococci is primarily associated with the presence of qacA/B and smr genes.

    Methodology: We used a culture-independent method to assess the prevalence of these genes in 78 DNA specimens recovered from the skin of 43 patients at catheter insertion sites in the arm that were covered with CHG dressings. Read More

    Simple Wound Irrigation in the Postoperative Treatment for Surgically Drained Spontaneous Soft Tissue Abscesses: Study Protocol for a Prospective, Single-Blinded, Randomized Controlled Trial.
    JMIR Res Protoc 2017 May 1;6(5):e77. Epub 2017 May 1.
    Lucerne Cantonal Hospital, Surgery Department, Lucerne, Switzerland.
    Background: Skin abscesses are a frequent encountered health care problem and lead to a significant source of morbidity. They consequently have an essential impact on the quality of life and work. To date, the type of aftercare for surgically drained abscesses remains under debate. Read More

    Skin allograft procurement and transplantation in Mashhad, Iran: Are burn patients' needs being met?
    Cell Tissue Bank 2017 Apr 24. Epub 2017 Apr 24.
    Burns Operating Room, Department of Burns and Reconstructive Surgery, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
    Only a single donor's tissue may save or improve lives of one hundred patients. Unfortunately, low governmental and media support of tissue procurement and transplantation programs is a worldwide problem. Loss of an effective tissue procurement program in many countries like Iran, may lead to loss of many thousands valuable tissues each year. Read More

    Tactical Combat Casualty Care and Wilderness Medicine: Advancing Trauma Care in Austere Environments.
    Emerg Med Clin North Am 2017 May;35(2):391-407
    Madigan Army Medical Center, 9040 Jackson Ave., Tacoma, WA 98431, USA.
    Tactical Combat Casualty Care (TCCC) is a set of evidence-based, best-practice prehospital trauma care guidelines customized for use on the battlefield. Military units that have trained all of their unit members in TCCC have now documented the lowest incidence of preventable deaths in the history of modern warfare and TCCC is now the standard for battlefield trauma care in the US Military. TCCC and wilderness medicine share the goal of optimizing care for patients with trauma in austere environments that impose significant challenges in both equipment and evacuation capability. Read More

    Pleural malignant mesothelioma in dental laboratory technicians: A case series.
    Am J Ind Med 2017 May;60(5):443-448
    Department of Preventive Medicine, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.
    Asbestos was used in dentistry as a binder in periodontal dressings and as lining material for casting rings and crucible. However, until now, only one case of malignant mesothelioma with occupational exposure to asbestos in dental practice has been reported. We present 4 pleural mesotheliomas out of 5344 cases identified in Lombardy, Italy, in 2000-2014. Read More

    Cost-effectiveness of silver dressings for paediatric partial thickness burns: An economic evaluation from a randomized controlled trial.
    Burns 2017 Jun 10;43(4):724-732. Epub 2017 Apr 10.
    Centre for Children's Burns and Trauma Research, Child Health Research Centre, The University of Queensland, Australia; Tissue Repair and Regeneration Program, Institute of Health and Biomedical Innovation, Queensland University of Technology, Australia; Pegg Leditschke Children's Burns Centre, Lady Cilento Children's Hospital, Brisbane, Australia; Institute of Health and Biomedical Innovation and School of Public Health & Social Work, Queensland University of Technology, Australia; Centre for Functioning and Health Research, Metro South Health, Australia.
    Background: Partial thickness burns of up to 10% total body surface area (TBSA) in children are common injuries primarily treated in the outpatient setting using expensive silver-containing dressings. However, economic evaluations in the paediatric burns population are lacking to assist healthcare providers when choosing which dressing to use. The aim of this study was to conduct a cost-effectiveness analysis of three silver dressings for partial thickness burns ≤10% TBSA in children aged 0-15 years using days to full wound re-epithelialization as the health outcome. Read More

    Surgery-Related Contact Dermatitis: A Review of Potential Irritants and Allergens.
    J Allergy Clin Immunol Pract 2017 Apr 7. Epub 2017 Apr 7.
    Division of Allergy, Asthma and Immunology, Scripps Clinic, San Diego, Calif.
    Surgical procedures utilize an increasing number of medical products including antiseptics, anesthetics, gloves, suture materials, tissue adhesives, topical antibiotics, and bandages. Many of these products have irritant potential. Allergic contact dermatitis has also been reported. Read More

    Improvised Vacuum-Assisted Closure for severe neck infection in poorly equipped conditions.
    J Stomatol Oral Maxillofac Surg 2017 Apr 6. Epub 2017 Apr 6.
    Service d'ORL et de Chirurgie Cervico-Maxillo-faciale, CHU Sylvanus Olympio, 08 BP 8146 Lomé, Togo.
    Introduction: Dental infections are common and are mainly due to dental caries. When left untreated, these infections can lead to severe life-threatening sepsis.

    Case Report: The authors reported a case of a severe odontogenic deep neck space infection in a 54-year-old male. Read More

    The Efficacy of Versajet™ Hydrosurgery System in Burn Surgery. A Systematic Review.
    J Burn Care Res 2017 Apr 4. Epub 2017 Apr 4.
    From the Department of Plastic Surgery, Democritus University in Thrace, Dragana, Alexandroupolis, Greece; and Department of Orthopaedics, Red Cross Hospital, Athens, Greece.
    Prompt debridement of burns and early grafting increase survival rates while reducing morbidity and length of hospitalization. Among the debridement methods, hydrosurgery is gaining popularity during the last decade. This review aims to review all available clinical evidence regarding the efficacy, safety, and cost-effectiveness of the hydrosurgical management of burns. Read More

    Cost-effectiveness analysis of single-use negative pressure wound therapy dressings (sNPWT) to reduce surgical site complications (SSC) in routine primary hip and knee replacements.
    Wound Repair Regen 2017 Apr 1. Epub 2017 Apr 1.
    Consultant Orthopaedic Surgeon, Robert Jones and Agnes Hunt Orthopaedic NHS Hospital Foundation Trust, Gobowen, Oswestry, SY10 7AG.
    We sought to evaluate the cost-effectiveness of single-use negative pressure wound therapy in patients undergoing primary hip and knee replacements using effectiveness data from a recently completed non-blinded randomized controlled trial. A decision analytic model was developed from UK National Health Service perspective using data from a single-centre trial. 220 patients were randomized to treatment with either single-use negative pressure wound therapy or standard care i. Read More

    Ludwik Bierkowski and the early days of general anaesthesia in the Polish soil in February 1847.
    Anaesthesiol Intensive Ther 2017 ;49(1):1-5
    Chair of History of Medicine, Jagiellonian University Collegium Medicum in Cracow, Poland.
    Ludwik Bierkowski belonged to the elite of surgeons of the first half of the 19th century. Educated in an excellent German university, Bierkowski had in-depth and comprehensive knowledge, a wide range of practical skills and was continuously eager to search for new solutions. He introduced cotton wool for wound dressings, experimentally determined the conditions of blood transfusions and published two outstanding anatomo-surgical atlases, which ranks him among the leading physicians of those days. Read More

    Prophylactic vacuum sealing drainage (VSD) in the prevention of postoperative surgical site infections in pediatric patients with contaminated laparotomy incisions.
    Medicine (Baltimore) 2017 Mar;96(13):e6511
    aDepartment of Pediatric General Surgery and Liver Transplantation, Children's Hospital, Chongqing Medical University, Chongqing bDepartment of Pathology, Linyi People's Hospital, Linyi, Shandong Province cMinistry of Education Key Laboratory of Child Development and Disorders, Children's Hospital, Chongqing Medical University, Chongqing, P.R. China.
    Surgical site infection (SSI) continues to be an issue in abdominal surgery, especially for contaminated (class III) and dirty-infected (class IV) wounds. Vacuum sealing drainage (VSD) was reported effective in the management of various types of wounds or skin grafts. Our goal was to investigate the efficacy of prophylactic VSD to better orient their medicosurgical care of high-risk incisions following laparotomy in a pediatric population. Read More

    Soft Tissue Reconstruction of Complete Circumferential Defects of the Upper Extremity.
    Arch Plast Surg 2017 Mar 15;44(2):117-123. Epub 2017 Mar 15.
    Division of Plastic Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
    Background: Upper extremity soft tissue defects with complete circumferential involvement are not common. Coupled with the unique anatomy of the upper extremity, the underlying etiology of such circumferential soft tissue defects represent additional reconstructive challenges that require treatment to be tailored to both the patient and the wound. The aim of this study is to review the various options for soft tissue reconstruction of complete circumferential defects in the upper extremity. Read More

    Primary Localized Cutaneous Amyloidosis: A Systematic Treatment Review.
    Am J Clin Dermatol 2017 Mar 24. Epub 2017 Mar 24.
    Department of Dermatology, University Hospital Jena, Erfurter Straße 35, Jena, 07743, Germany.
    Background: Primary localized cutaneous amyloidosis (PLCA) is characterized by extracellular deposition of heterogenic amyloid proteins in the skin without systemic involvement. Lichen amyloidosis, macular amyloidosis, and (primary localized cutaneous) nodular amyloidosis are different subtypes of PLCA.

    Objective: The aim of this study was to review the current reported treatment options for PLCA. Read More

    An Alternative Treatment Strategy for Complicated Chronic Wounds: Negative Pressure Therapy over Mesh Skin Graft.
    Biomed Res Int 2017 19;2017:8395219. Epub 2017 Feb 19.
    "Valdoni" Surgery Department, Plastic and Reconstructive Surgery Unit, "Sapienza" University of Rome, Viale del Policlinico 155, 00161 Roma, Italy.
    Extensive skin defect represents a real problem and major challenge in plastic and reconstructive surgery. On one hand, skin grafts offer a practical method to deal with skin defects despite their unsuitability for several complicated wounds. On the other hand, negative pressure wound therapy (NPWT), applied before skin grafting, promotes granulation tissue growth. Read More

    Two Decades of Saving Lives on the Battlefield: Tactical Combat Casualty Care Turns 20.
    Mil Med 2017 Mar;182(3):e1563-e1568
    Committee on Tactical Combat Casualty Care, Joint Trauma System, U.S. Army Institute of Surgical Research, Joint Base San Antonio, San Antonio, TX 78234.
    Background: Twenty years ago, the original Tactical Combat Casualty Care (TCCC) article was published in this journal. Since TCCC is essentially a set of best-practice prehospital trauma care guidelines customized for use on the battlefield, the presence of a journal with a specific focus on military medicine was a profound benefit to the initial presentation of TCCC to the U.S. Read More

    Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: a systematic review.
    J Wound Care 2017 Mar;26(3):107-114
    Professor of Vascular Surgery and Consultant Vascular Surgeon, Academic Vascular Surgical Unit, Hull Royal Infirmary, Anlaby Road, Hull, HU3 2JZ, UK.
    Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care professional's armamentarium and have been used in a variety of acute and chronic wounds. This systematic review aims to assess the evidence supporting the use of DACC-coated dressings in the clinical environment. Read More

    Management of acute complex traumatic wound with a dermal regeneration template: Case report.
    S Afr J Surg 2016 Nov;54(4):52
    Department: Plastic and Reconstructive Surgery & Burns, Kimberley Hospital Complex, Northern Cape Province.
    Background: Acute complex traumatic wounds of the lower limbs are usually managed by a combination of multiple debridements, dressing changes, and specialized surgical procedures which may include tissue transfers for the reconstruction of the soft tissue injury. The recovery is lengthy, and the outcome dependent on the initial injury, the surgical procedures undertaken and rehabilitation programs with a multidisciplinary team.

    Method: A nine-year-old male patient presented to Kimberly Hospital with an extensive soft tissue injury of the leg associated with a tibia fracture caused by a high velocity pedestrian vehicle accident. Read More

    A refined surgical treatment modality for bromhidrosis: Subcutaneous scissor with micropore.
    Dermatol Ther 2017 Mar 6. Epub 2017 Mar 6.
    Department of Dermatology, Third People's Hospital of Hangzhou, Affiliated Third Hospital of Hangzhou, Anhui Medical University, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China.
    Axillary bromhidrosis has a strong negative effect on one's social life. A high success rate and few complications are criteria for a surgical treatment. The objective of this study was to evaluate a new surgical treatment modality for bromhidrosis: subcutaneous scissor with micropore. Read More

    Wounds difficult to heal: an effective treatment strategy
    Curr Vasc Pharmacol 2017 03 1. Epub 2017 Mar 1.
    Dept of Anatomy, Histology, Forensic Medicine and Orthopedics - "Sapienza" University of Rome, Italy.
    Objective: Treatment of wounds difficult to heal concerns 50% of the elderly population in Italy and is therefore an extreme relevance social burden. The present study shows how the treatment with autologous leuco-platelets reduces the healing time of wounds improving the functional recovery.

    Patients And Methods: One hundred patients with ulcers of the legs were divided in two groups: 1) 50 patients treated with conventional therapies; 2) 50 patients treated with autologous leuco-platelet concentrate (LPC) and HYAFF as a scaffold. Read More

    Evaluation of horn bud wound healing following cautery disbudding of preweaned dairy calves treated with aluminum-based aerosol bandage.
    J Dairy Sci 2017 May 2;100(5):3922-3929. Epub 2017 Mar 2.
    Department of Clinical Sciences, Colorado State University, Fort Collins 80523. Electronic address:
    Pain management during and following disbudding procedures has been studied extensively, though few studies have evaluated wound healing following cautery disbudding in dairy calves. The purpose of this study was to observe wound healing following cautery disbudding with or without treatment using a topical aluminum-based aerosol bandage (ALU) in preweaned dairy calves. Dairy calves were disbudded within the first 3 wk of life using a standard cautery disbudding protocol. Read More

    Wound management of ulcerated haemangioma of infancy - an audit.
    Int Wound J 2017 Mar 1. Epub 2017 Mar 1.
    The Royal Children's Hospital, Department of Plastic and Maxillofacial Surgery, Murdoch Childrens Research Institute and the Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.
    Haemangioma of infancy, a benign tumour of blood vessels, is the most common tumour of infancy. Ulceration, the most common complication, presents a unique wound care challenge. A retrospective audit of medical records of children with haemangioma of infancy who presented to the Royal Children's Hospital, Melbourne, Australia, between January 2000 and December 2014 was undertaken with an aim to examine wound management of ulcerated haemangioma of infancy. Read More

    Applying vacuum to accomplish reduced wound infections in laparoscopic pediatric surgery.
    J Pediatr Surg 2017 May 30;52(5):849-852. Epub 2017 Jan 30.
    Department of Surgery, Division of Pediatric Surgery, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Pediatrics & Child Health and Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:
    Introduction: The prevention of surgical site infections has received little attention in pediatric surgery. Negative pressure wound therapy is used to treat complex wounds. We hypothesized that this principle could reduce wound infection rates following laparoscopic surgery. Read More

    Pseudoaneurysm of the Radial Artery on the Hand Secondary to Stabbing.
    Ann Vasc Surg 2017 May 27;41:280.e7-280.e10. Epub 2017 Feb 27.
    Department of Radiology, Ondokuz Mayis University, Samsun, Turkey. Electronic address:
    Pseudoaneurysm of the radial artery is extremely rare. It usually occurs secondary to trauma, interventional procedures, and infections. Symptoms occur due to mass effect by the pseudoaneurysm, digital ischemia, or nerve suppression. Read More

    Safety and Effectiveness of Enoxaparin as Venous Thromboembolism Prophylaxis after Gastric Cancer Surgery in Japanese Patients.
    Am Surg 2016 Dec;82(12):1232-1237
    Department of Gastroenterological Surgery, Kameda Medical Center, Chiba, Japan.
    Routine prophylaxis for venous thromboembolism (VTE) has been recommended after surgery not only in the West but also in Asia recently. The primary objective of this study was to investigate the safety and effectiveness of enoxaparin as a prophylaxis in patients undergoing distal, proximal, or total gastrectomy (TG) for gastric cancers. A total of 565 patients who underwent gastrectomy for gastric cancer were reviewed retrospectively. Read More

    A case of IV degree on acute radiation dermatitis in China.
    Int J Surg Case Rep 2017 2;32:19-21. Epub 2017 Feb 2.
    Department of Drug, Jilin University School of Pharmaceutical Sciences, Changchun, 130021, China. Electronic address:
    This report investigates the nursing procedure of a case of adjuvant therapy of rectal cancer on IV degree of acute radiation dermatitis patients in the penis and scrotum junction. The lesion degree gradually increased. Fixation of the dressing was difficult in the penis and scrotum junction. Read More

    A Biodegradable Hemostatic Gelatin/Polycaprolactone Composite for Surgical Hemostasis.
    Ann Plast Surg 2017 Mar;78(3 Suppl 2):S124-S128
    From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center; †Institute of Polymer Science and Engineering, National Taiwan University; and ‡Department of Orthopedics, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan, Republic of China.
    Massive bleeding is the leading cause of battlefield-related deaths and the second leading cause of deaths in civilian trauma centers. One of the challenges of managing severe wounds is the need to promote hemostasis as quickly as possible, which can be achieved by using hemostatic dressings. In this study, we fabricated 2 kinds of gelatin/polycaprolactone composites with 2 ratios of gelatin/polycaprolactone, 1:1 and 2:1 (GP11 and GP21, respectively). Read More

    Current approach to liver traumas.
    Int J Surg 2017 Mar 11;39:255-259. Epub 2017 Feb 11.
    Kartal Research and Education Hospital, Turkey.
    Introduction: Liver injuries remain major obstacle for successful treatment, due to size and location of the liver. Requirement for surgery should be determined by clinical factors, most notably hemodynamical state. In this present study we tried to declare our approach to liver traumas. Read More

    Prevention of postsurgical wound dehiscence after abdominal surgery with NPWT: a multicentre randomised controlled trial protocol.
    J Wound Care 2017 Feb;26(Sup2):S23-S26
    Professor of Primary Health Care and Community, School of Nursing and Midwifery, Curtin University, Perth, WA, Australia; and Wound Management Innovation Cooperative Research Centre (WMICRC); and Silver Chain Group, WA, Australia.
    Objective: The effectiveness of negative pressure wound therapy (NPWT) in the prevention of postoperative surgical wound dehiscence (SWD) is the subject of much debate and remains to be determined. This study will identify individuals at risk of postoperative SWD and trial the use of NPWT as a prophylactic measure against the occurrence of SWD, compared with a non-NPWT standard surgical dressing (SSD).

    Method: A prospective multicentre randomised controlled trial comparing NPWT dressing against standard surgical dressings (SSD) will be conducted. Read More

    Healing of an arterial leg ulcer by compression bandaging: a case report.
    J Wound Care 2017 Feb;26(Sup2):S18-S22
    Emeritus Professor, SERGAS (Service Galego of Health) LUGO/Spain.
    This case report demonstrates that arterial ulcers may heal with compression therapy. The patient was a 72-year-old woman with elevated blood pressure and type II diabetes mellitus, who underwent angiography because of a painful, non-healing ulcer over the shin. The angiography showed multisegment arterial occlusive disease, not amenable to surgical revascularisation. Read More

    [Management of lymphatic fistulas in the groin from a surgeon's perspective].
    Chirurg 2017 Feb 8. Epub 2017 Feb 8.
    Contilia Herz- und Gefäßzentrum, Klinik für Gefäßchirurgie und Phlebologie, Elisabeth-Krankenhaus Essen, Essen, Deutschland.
    Background: The postoperative occurrence of lymph fistulas in the groin is a complication that should be taken seriously. These fistulas cause an increase in morbidity and can support local and ascending infections. The treatment of this complication ranges from conservative procedures, such as compression dressings and bed rest to operative treatment with detection of the fistulas and ligation, negative pressure wound therapy (NPWT) or even muscle flaps. Read More

    On-Demand Dissolution of Chemically Cross-Linked Hydrogels.
    Acc Chem Res 2017 Feb 7;50(2):151-160. Epub 2017 Feb 7.
    Departments of Chemistry, Biomedical Engineering, and Medicine, Boston University , 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.
    The formation and subsequent on-demand dissolution of chemically cross-linked hydrogels is of keen interest to chemists, engineers, and clinicians. In this Account, we summarize our recent advances in the area of dissolvable chemically cross-linked hydrogels and provide a comparative discussion of other recent hydrogel systems. Using biocompatible macromonomers, we developed a library of cross-linked dendritic hydrogels that possess favorable properties, including biocompatibility, tissue adhesion, and swelling. Read More

    A systematic review and meta-analysis of clinical outcomes associated with nanocrystalline silver use compared to alternative silver delivery systems in the management of superficial and deep partial thickness burns.
    Burns 2017 Feb 1. Epub 2017 Feb 1.
    Department of Plastic Surgery, Kuopio University Hospital, Kuopio, Finland.
    Objective: The purpose of this systematic review and meta-analysis was to assess the clinical effectiveness of nanocrystalline silver compared to alternative silver delivery systems (silver sulphadiazine [SSD] and silver nitrate) in adults and children with superficial and deep partial thickness burns.

    Methods: PubMed, EMBASE, Cochrane and other databases were searched to identify relevant randomised controlled trials and observational studies.

    Results: Eight studies that assessed both nanocrystalline silver and SSD and one study that compared nanocrystalline silver vs. Read More

    Delayed Surgical Debridement and Use of Semiocclusive Dressings for Salvage of Fingers After Purpura Fulminans.
    Hand (N Y) 2016 Dec 3;11(4):NP34-NP37. Epub 2016 Aug 3.
    Pontificia Universidad Católica de Chile, Santiago, Chile.
    Background: Purpura fulminans is a condition characterized by rapidly evolving skin necrosis and disseminated intravascular coagulation. Early recognition and aggressive supportive management has led to a decrease in its mortality rate, but most of these patients must undergo extensive soft tissue debridement and partial or total limb amputation. There is controversial evidence about the timing of surgery, suggesting that some patients may benefit from delayed debridement with limb preservation. Read More

    Tourniquets do not increase the total blood loss or re-amputation risk in transtibial amputations.
    World J Orthop 2017 Jan 18;8(1):62-67. Epub 2017 Jan 18.
    Christian Wied, Peter T Tengberg, Gitte Holm, Thomas Kallemose, Anders Troelsen, Morten T Kristensen, Department of Orthopedic Surgery, Copenhagen University Hospital Hvidovre, 2650 Hvidovre, Denmark.
    Aim: To investigate the total blood loss (TBL) and the safety with respect to the re-amputation rate after transtibial amputation (TTA) conducted with and without a tourniquet.

    Methods: The study was a single-centre retrospective cohort study of patients with a primary TTA admitted between January 2013 and April 2015. All patients with a primary TTA were assessed for inclusion if the amputation was performed because of arteriosclerosis or diabetic complications. Read More

    Calvarial metastasis of renal cell carcinoma.
    BMJ Support Palliat Care 2017 Jan 31. Epub 2017 Jan 31.
    Service de Chirurgie Plastique, Reconstructrice et Esthétique, Hôpital Européen Georges Pompidou, Université Paris-Descartes, Paris, France.
    The calvarium is an extremely unusual site of metastasis of renal cell carcinoma. We report a 62-year-old man who was enrolled for palliative medical management for an exophytic calvarial metastasis. His quality of life was greatly compromised with everyday local care and bandages due to recurrent events of infection and bleeding, limiting his social life. Read More

    [Postoperative wound infections : Diagnosis, classification and treatment].
    Chirurg 2017 May;88(5):385-394
    Klinik für Allgemein- und Viszeralchirurgie, Sana-Klinikum Lichtenberg, Berlin, Deutschland.
    Background: Surgical site infections are a frequent complication of surgery and a severe burden for the patient as well as for the healthcare system. Sound knowledge of the disease pattern is an essential prerequisite for effective therapy.

    Objective: This article presents an overview of the diagnosis, classification and treatment options for surgical site infections. Read More

    A non-invasive tool for detecting cervical cancer odor by trained scent dogs.
    BMC Cancer 2017 Jan 26;17(1):79. Epub 2017 Jan 26.
    Laboratorio de Oncología Genómica, Unidad de Investigación Médica en Enfermedades Oncológicas, UMAE Hospital de Oncología, CMN- SXXI-IMSS, Av. Cuauhtémoc 330, Col. Doctores, Del. Cuauhtémoc, 06720, Mexico City, Mexico.
    Background: Cervical Cancer (CC) has become a public health concern of alarming proportions in many developing countries such as Mexico, particularly in low income sectors and marginalized regions. As such, an early detection is a key medical factor in improving not only their population's quality of life but also its life expectancy. Interestingly, there has been an increase in the number of reports describing successful attempts at detecting cancer cells in human tissues or fluids using trained (sniffer) dogs. Read More

    Economic case for intraoperative interventions to prevent surgical-site infection.
    Br J Surg 2017 Jan;104(2):e55-e64
    Centre for Applied Health Economics, School of Medicine, Menzies Health Institute of Queensland, Griffith University, Brisbane, Queensland, Australia.
    Background: Surgical-site infection (SSI) occurs in 1-10 per cent of all patients undergoing surgery; rates can be higher depending on the type of surgery. The aim of this review was to establish whether (or not) surgical hand asepsis, intraoperative skin antisepsis and selected surgical dressings are cost-effective in SSI prevention, and to examine the quality of reporting.

    Methods: The authors searched MEDLINE via Ovid, CINAHL via EBSCO, Cochrane Central and Scopus databases systematically from 1990 to 2016. Read More

    Importance of biofilm formation in surgical infection.
    Br J Surg 2017 Jan;104(2):e85-e94
    5D Health Protection Group Ltd, Liverpool Bio-Innovation Hub, William Duncan Building, West Derby Street, Liverpool L7 8TX, UK.
    Background: Biofilms are ubiquitous, and have been observed in both acute and chronic wounds. Their role in wound healing and infection, however, remains controversial. The aim of this review was to provide an overview of the role and relevance of biofilms to surgical wounds. Read More

    A Retrospective Comparison of the Performance of Two Negative Pressure Wound Therapy Systems in the Management of Wounds of Mixed Etiology.
    Adv Wound Care (New Rochelle) 2017 Jan;6(1):33-37
    Smith & Nephew , Hull, United Kingdom .
    Objective: Negative pressure wound therapy (NPWT) has been shown to be effective in the management of chronic and surgical wounds. The two most widely used modalities of NPWT are vacuum-assisted closure (V.A. Read More

    Examination of the early wound healing process under different wound dressing conditions.
    Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Mar 11;123(3):310-319. Epub 2016 Nov 11.
    Field of Oral and Maxillofacial Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
    Objective: Various types of wound-healing dressings have been used to assist in the healing of surgical wounds. We analyzed the wound-healing process in an animal model using different existing wound dressings.

    Study Design: Full-thickness defects were created using a biopsy punch on the backs of 7-week-old rats. Read More

    Embedded Fragment Removal and Wound Debridement in a Non-US Partner Force Soldier.
    J Spec Oper Med Winter 2016;16(4):114-116
    Objective: Review application of telemedicine support for removal of fragment and wound management. Clinical context: Special Forces Operational Detachment- Alpha deployed in Central Command area of responsibility operating out of a small aid station ("house" phase of prolonged field care) Organic expertise: 18D Special Operations Combat medic Closest medical support: Combined Joint Special Operations Task Force (CJSOTF) surgeon located in another country; thus, all consults were either via telephone or over Secret Internet Protocol Router e-mail. Earliest evacuation: NA. Read More

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