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Orthop Res Rev 2018 23;10:83-91. Epub 2018 Oct 23.

The Reading Shoulder Unit, Berkshire Independent Hospital Coley Park, Swallows Croft, Reading, Berkshire, UK,

The painful shoulder is the most common condition seen in specialist shoulder clinics. It is often associated with lack of range of motion and reduced shoulder function. Lack of sleep and difficulties in performing basic daily life activities are common findings. Read More

Orthop Res Rev 2018 3;10:63-72. Epub 2018 Oct 3.

Department of Orthopaedics, University of Milan,

Calcific tendinopathy (CT) of the shoulder is a common, painful condition characterized by the presence of calcium deposits in the rotator cuff tendons. Current theories indicate that CT may be the result of a cell-mediated process in which, after a stage of calcium deposition, calcifications are spontaneously resorbed. However, in a minority of cases, this self-healing process is somehow disrupted, resulting in symptoms. Read More

Connect Tissue Res 2019 Feb 12. Epub 2019 Feb 12.

d Department of Orthopaedic Surgery , School of Medicine and Gyeongsang National University Changwon Hospital , Changwon , Republic of Korea.

Purpose: Neuronal theory regarding rotator cuff degeneration has developed from the findings that glutamate, an amino acid and an excitatory neurotransmitter, is present in increased concentrations in tendon tissues with tendinopathy and that glutamate induces cell death in fibroblasts of origin in rat supraspinatus tendon. The purpose of the current study was to determine whether N-acetylcysteine (NAC) has cytoprotective effects against glutamate-induced fibroblast death.

Materials And Methods: Primary cultured fibroblasts were obtained from rat supraspinatus tendons. Read More

Int J Sports Phys Ther 2019 Feb;14(1):148-158

Via di Santa Zita, Genoa, Italy.

Background And Purpose: Rotator cuff (RC) tendinopathy is a common disorder affecting many individuals, both in athletic and sedentary settings. Etiology of RC pathology or the most effective conservative treatment are not totally understood. The Mechanical Diagnosis and Treatment (MDT®) method is a widely known rehabilitative technique that allows therapists to diagnose and treat spinal, and peripheral mechanical disorders. Read More

Am J Phys Med Rehabil 2018 Dec 4. Epub 2018 Dec 4.

IRCCS Istituto Ortopedico Galeazzi Via Riccardo Galeazzi, 4, 20161 Milan, Italy.

Objective: The primary aim was to ascertain if unilateral shoulder pain is implicated in strength reduction both on the ipsilateral and contralateral side. Secondarily, we aimed to determine whether strength was affected by sonographic tendon abnormalities.

Design: A total of 122 subjects were evaluated. Read More

Br J Radiol 2019 Jan 28:20180951. Epub 2019 Jan 28.

1 Department of Radiodiagnosis and Imaging, Bharati Hospital and Research Center, Dhankawadi , Pune , India.

Objective:: This study assessed the association between tendon stiffness on sonoelastography and grades of tendinopathy on MRI in patients with supraspinatus tendinopathy.

Methods:: 25 consecutive adult patients with clinically suspected supraspinatus tendinopathy and no prior history of trauma referred for MRI of the shoulder were selected for this study. The supraspinatus tendinopathy was graded in consonance with MRI findings (Grade I, normal; Grade II, mild tendinopathy; Grade III, moderate tendinopathy; and Grade IV, marked tendinopathy). Read More

Ortop Traumatol Rehabil 2018 Dec;20(6):499-505

Physical and Rehabilitation Medicine Department, Campus Bio-Medico University, Rome, Italy.

Background: Rotator cuff tendinopathy (RoCT) is a common pathology among adults. Kinesio-taping (KT) represents a possible rehabilitative treatment. The aim of the present study is to investigate the efficacy of a combination of three different applications of KT combined with a standardized protocol of rehabilitative exercises in reducing pain and in functional recovery in patients affected by RoCT. Read More

Am J Transl Res 2018 15;10(11):3291-3309. Epub 2018 Nov 15.

Department of Clinical and Translational Science and Orthopedic Surgery, School of Medicine, Creighton University Omaha, NE 68178, USA.

Derangements in tendon matrisome are pathognomonic for musculoskeletal disorders including rotator cuff tendinopathies (RCT). Collagen type-1 accounts for more than 85% of the dry weight of tendon extracellular matrix (ECM). The understanding of basic tendon physiology, organization of ECM, structure and function of component biomolecules of matrisome and the underlying regulatory mechanisms reveal the pathological events associated with RCT. Read More

Disabil Rehabil 2019 Jan 17:1-6. Epub 2019 Jan 17.

a Physiotherapy Program, Department of Health Sciences School of Sciences , European University of Cyprus , Nicosia , Cyprus.

Background: The Shoulder Pain and Disability Index is one of the most common questionnaire to evaluate the impact of shoulder disorders on function. There is no valid and reliable Greek version of the Shoulder Pain and Disability Index available at present for all shoulder disorders. Therefore, the aim of the current study was to test the reliability and validity of the Shoulder Pain and Disability Index in patients with shoulder pain for at least four weeks. Read More

BMJ Open Sport Exerc Med 2018 26;4(1):e000477. Epub 2018 Dec 26.

Faculty of Medicine, Laval University, Quebec City, Canada.

Objectives: Rotator cuff tendinopathies are the most common shoulder disorders. As persistent symptoms lasting more than 3 months have been shown to be a strong indicator of poor outcomes, it is important to have successful interventions in the acute stage. However, there is no evidence yet to guide clinical interventions in an acute pain context. Read More

BMC Med Genet 2018 Dec 20;19(1):217. Epub 2018 Dec 20.

Department of Orthopaedics and Trauma Surgery, Campus Bio-Medico University of Rome, Rome, Italy.

Background: The incidence of RC tears increases with aging, affecting approximately 30 to 50% of individuals older than 50 years, and more than 50% of individuals older than 80 years. Intrinsic factors (age or gender), extrinsic factors (sports activity or occupation), and biological factors were identified in the onset and progression of RC tears. The attention in the study of aetiology of RC tendinopathy has shifted to the identification of gene variants. Read More

J Manipulative Physiol Ther 2018 Oct 17;41(8):665-671. Epub 2018 Dec 17.

Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Taiwan.

Objective: The purpose of this study was to investigate the effect of comprehensive postural instructions and range of motion (ROM) exercises via educational videos for shoulder injury prevention and functional improvement of the hemiplegic shoulder after acute stroke.

Methods: In this prospective cohort study, 48 subacute stroke patients with hemiplegia were enrolled and divided into 2 groups (23 in experimental group and 25 in control group). In the control group (n = 25), the patients performed conventional rehabilitation for 5 days per week. Read More

Eur J Phys Rehabil Med 2018 Dec 13. Epub 2018 Dec 13.

Graduate Institute of Sports Science, National Taiwan Sports University, Taoyuan, Taiwan -

Background: Rotator cuff lesions are common causes of shoulder pain. Although patients with symptoms caused by chronic rotator cuff tendinopathy can be treated using conservative treatments, some of them may still experience refractory symptoms. Hypertonic dextrose prolotherapy (DPT) may be another treatment choice for these refractory symptoms. Read More

Sex Disabil 2018 30;36(4):305-311. Epub 2018 Oct 30.

Medical Research Department, Artanim Foundation, Geneva, Switzerland.

The aim of this study was to analyze the occurrence of rotator cuff impingement due to reduction of subacromial space height during complex shoulder motion to determine safety of sexual activities. The hypothesis was that such activities could be deleterious if not performed with precaution. To use a patient-specific 3D measurement technique coupling medical imaging and optical motion capture to evaluate the safety of various sexual positions according to subacromial compression. Read More

Int J Sports Phys Ther 2018 Dec;13(6):1083-1094

Background And Purpose: Tendinopathy of the supraspinatus muscle is a frequent cause of shoulder pain. Although it is a common condition, the pathophysiology is not fully understood. The purpose of this clinical commentary is to provide an overview of the pathophysiology of supraspinatus tendinopathy and discuss the conservative treatment solutions. Read More

J Orthop Sports Phys Ther 2018 Nov 30:1-43. Epub 2018 Nov 30.

Faculty of Medicine, University of Sherbrooke, Sherbrooke (QC), Canada.

Study Design: Single-blind, randomized controlled trial.

Background: Treatments for rotator cuff (RC) tendinopathy include RC muscle strengthening to promote better muscle recruitment in order to minimize subacromial narrowing during active movement. Glenohumeral adductors recruitment has also been shown to prevent such narrowing in asymptomatic individuals; therefore, adding glenohumeral adductor coactivation during RC strengthening could enhance the efficacy of RC strengthening. Read More

BMC Musculoskelet Disord 2018 Nov 23;19(1):408. Epub 2018 Nov 23.

Department of Occupational Science and Technology, University of Wisconsin-Milwaukee, 161 W Wisconsin Ave, Suite 6000, Milwaukee, WI, 53203-2602, USA.

Background: Glenohumeral pain and rotator cuff tendinopathy (RCT) are common musculoskeletal complaints with high prevalence among working populations. The primary proposed pathophysiologic mechanisms are sub-acromial RC tendon impingement and reduced tendon blood flow. Some sleep postures may increase subacromial pressure, potentially contributing to these postulated mechanisms. Read More

Am J Phys Med Rehabil 2018 Nov 17. Epub 2018 Nov 17.

From the Kessler Foundation, West Orange, NJ (Hogaboom); Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Newark, NJ (Hogaboom); Human Engineering Research Laboratories, VA Pittsburgh Healthcare System, Pittsburgh, PA (Worobey, Boninger); Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA (Onishi, Worobey, Boninger); Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA (Onishi), Department of Rehabilitation Science and Technology, University of Pittsburgh, Pittsburgh, PA (Boninger).

Microdialysis quantifies in vivo soft-tissue biochemical concentrations via passive diffusion of interstitial molecules through a porous membrane into a dialysate. The purpose of this pilot study was to evaluate a technique to measure inflammatory cytokines associated with rotator cuff tendinopathy by inserting a microdialysis catheter into the posterior glenohumeral joint (GHJ). The technique was tested in a convenience sample of six pain-free, able-bodied Veterans. Read More

Clin Biomech (Bristol, Avon) 2019 Jan 10;61:16-21. Epub 2018 Nov 10.

Center for Interdisciplinary Research in Rehabilitation and Social Integration, CIUSSS-CN, Quebec City, Quebec, G1M 2S8, Canada; Department of Rehabilitation, Faculty of Medicine, Laval University, Quebec, G1V 0A6, Canada. Electronic address:

Background: Kinesiotaping is widely used for the rehabilitation of rotator cuff tendinopathy. It has been argued to reduce symptoms and functional limitations through improvement of proprioceptive feedback. In addition, kinesiotaping has been reported to increase the subacromial space in healthy subjects. Read More

Mil Med 2018 Nov 13. Epub 2018 Nov 13.

Center for Interdisciplinary Research in Rehabilitation and Social Integration, Rehabilitation Institute, Quebec City, Quebec, Canada.

Introduction: Shoulder pain, a leading reason to consult a physician or physiotherapist, continues to be a challenge to rehabilitate, particularly with a military population. A rotator cuff (RC) tendinopathy, the most important source of shoulder pain, is one of the leading reasons for sick leave or a discharge from active military service. Research encourages the use of exercise prescription for the management of a RC tendinopathy, however the ideal method of delivery (group setting versus one-on-one) remains uncertain. Read More

J Ultrasound 2018 Dec 10;21(4):351-354. Epub 2018 Nov 10.

Unit of Ultrasound in Internal Medicine, Department of Medicine and Science of Aging, "G. d'Annunzio" University, Chieti, Italy.

Calcific tendinopathy is characterized by the deposition of calcium, mostly hydroxyapatite crystals, in tendons. Women are more frequently affected than men, with prevalence in the fourth and fifth decades of life. This condition has been reported between 2. Read More

BMJ Open Sport Exerc Med 2018 19;4(1):e000414. Epub 2018 Oct 19.

School of Health and Social Work, University of Hertfordshire, Hatfield, UK.

Study Design: Multicentre, double-blind, placebo-controlled randomised clinical trial.

Objectives: To compare the effectiveness of long chain omega-3 polyunsaturated fatty acids (PUFAs) as part of the management for people diagnosed with rotator cuff related shoulder pain (RCRSP).

Summary Of Background: Although there is no robust evidence to support their use, omega-3 PUFAs have been recommended for those with tendinopathy due to their potential to moderate inflammation. Read More

Curr Rev Musculoskelet Med 2018 Dec;11(4):624-634

Department of Orthopedic Surgery, Stanford University, 450 Broadway St, Redwood City, CA, USA.

Purpose Of Review: This review evaluates current clinical literature on the use of platelet-rich plasma (PRP), including leukocyte-rich PRP (LR-PRP) and leukocyte-poor PRP (LP-PRP), in order to develop evidence-based recommendations for various musculoskeletal indications.

Recent Findings: Abundant high-quality evidence supports the use of LR-PRP injection for lateral epicondylitis and LP-PRP for osteoarthritis of the knee. Moderate high-quality evidence supports the use of LR-PRP injection for patellar tendinopathy and of PRP injection for plantar fasciitis and donor site pain in patellar tendon graft BTB ACL reconstruction. Read More

SICOT J 2018 19;4:45. Epub 2018 Oct 19.

Orthopaedic Department, University Hospital of Ioannina, Ioannina, Greece.

Background: Calcified tendinopathy of the rotator cuff is one of the most common conditions concerning the shoulder pathology. It is characterized by a reactive calcification that affects the tendons being part of the rotator cuff. The reported prevalence varies from 2. Read More

Am J Sports Med 2018 Nov 12;46(13):3142-3154. Epub 2018 Oct 12.

Department of Laboratory Medicine, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Dongjak-gu, Seoul, Republic of Korea.

Background:: Although platelet-rich plasma (PRP) is a popular option for rotator cuff disease, the underlying mechanism of PRP and its clinical indications are unclear. Further, some kinds of PRP might be detrimental to patients. Allogenic PRP prepared through a standardized process and fully characterized could eliminate variations in PRP as well as uncertainties regarding its use in each patient, which could provide clues about its mechanism of action and indications for its use. Read More

Br J Sports Med 2019 Feb 9;53(4):251-262. Epub 2018 Oct 9.

Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Objective: To produce a best evidence synthesis of the clinical effects of topical glyceryl trinitrate (GTN) in the treatment of tendinopathies.

Design: A systematic review of published randomised controlled trials (RCTs) of the use of GTN in patients with tendinopathy.

Data Sources: MEDLINE, Embase, Scopus and CINAHL from database inception to January 2018. Read More

Knee Surg Sports Traumatol Arthrosc 2018 Oct 3. Epub 2018 Oct 3.

Department of Orthopedics, University Hospital North Norway, 9038, Tromsø, Norway.

Purpose: Tendon disorders are a major problem in the general population. It is known that rotator cuff tendinopathy contributes to osteoarthritis (OA) of the shoulder. The aim of the study was to analyse the presence of tendinopathy in patients with shoulder OA and an intact rotator cuff, using a multimodal approach. Read More

Radiologia 2018 Nov - Dec;60(6):465-475. Epub 2018 Sep 28.

Sección de Radiología Musculoesquelética, Servicio de Radiodiagnóstico, Hospital Universitario Virgen de las Nieves, Granada, España.

Platelet-rich plasma (PRP) is a preparation for therapeutic purposes that is increasingly accepted for various musculoskeletal disorders, due to its theoretical potential to repair tissues with poor healing capacity. Several randomised clinical trials have investigated the capacity of PRP to repair tendons, ligaments, muscles and cartilage, and to date there is level 1a evidence to support its use for lateral epicondylitis, osteoarthritis of the knee, plantar fasciitis and rotator cuff tendinopathy; and level 1b for patellar tendinopathy and osteoarthritis of the hip. Retrospective cohort studies and case series describe promising results with PRP for treating other musculoskeletal disorders. Read More

Curr Rev Musculoskelet Med 2018 Dec;11(4):566-572

University of Connecticut Health Center, 263 Farmington Ave, Farmington, CT, USA.

Purpose Of Review: Platelet-rich plasma (PRP) contains numerous growth factors and cytokines that potentially offer an alternative treatment modality to assist in the healing of multiple musculoskeletal issues. The purpose of this review was to examine the latest literature on the use of PRP for various ligament and tendon pathologies.

Recent Findings: Recent literature has shown moderate- to high-quality evidence that PRP can have positive clinical effects in certain conditions such as lateral epicondylitis and rotator cuff tendinopathy. Read More

Photomed Laser Surg 2018 Sep;36(9):506-513

3 Department of Rehabilitation Medicine and Physical Therapy, King Faisal Hospital , Makkah, Saudi Arabia .

Objective: The purpose of the present study was to investigate the long-term effect of pulsed Nd:YAG laser on the treatment of rotator cuff tendinopathy.

Methods: Sixty patients with rotator cuff tendinopathy participated and completed the study. The mean age was 50. Read More

Electromagn Biol Med 2018 5;37(4):175-183. Epub 2018 Sep 5.

a Department of Orthopaedic Surgery and Traumatology , Universitätsklinikum Schleswig-Holstein , Kiel , Germany.

Rotator cuff (RC) tendinopathy is the most common cause of shoulder pain. The effectiveness of electromagnetic transduction therapy (EMTT), a high energetic pulsed electromagnetic field therapy in this field has not been tested yet in combination with extracorporeal shock wave therapy (ESWT). A total of 86 patients with RC tendinopathy were randomized to undergo three sessions of ESWT in combination with 8 sessions of EMTT or sham-EMTT. Read More

Med Ultrason 2018 Aug;20(3):335-341

University of Belgrade School of Medicine, Clinic for Orthopedic Surgery and Traumatology, Clinical Center of Serbia, Belgrade, Serbia.

Aims: Autologous conditioned serum (ACS; marketed as Orthokine®) is an autologous blood product that has previously shown efficacy in treatment of joint osteoarthritis, spinal radiculopathy, tendon and muscle injuries in randomized controlled trials. In this 24-week, randomized, double-blind study, we compared the efficacy and safety of ACS with glucocorticoid (betamethasone) injections in chronic supraspinatus tendinopathy patients.

Material And Methods: Thirty-two patients with chronic supraspinatus tendinopathy were enrolled in the study. Read More

J Chiropr Med 2018 Jun 14;17(2):82-89. Epub 2018 Jun 14.

Department of Electrical and Electronic Engineering, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.

Objective: The purpose of this study was to analyze the influence of thoracic spinal manipulation (SM) on autonomic modulation and heart rate in patients with rotator cuff tendinopathy.

Methods: The design of the study was quasi-experimental. Participants were divided into 3 study groups: the asymptomatic group (n = 30), which received SM; the tendinitis group (TG, n = 30), which received SM; and the placebo group (PG, n = 30), which received placebo manipulation. Read More

Int Orthop 2018 Aug 29. Epub 2018 Aug 29.

Department of Orthopaedics and Traumatology, School of Medicine, Koc University, Istanbul, Turkey.

Purpose: Magnetic resonance (MRI) is a valuable imaging method which can detect pre-operative rotator cuff tear characteristics accurately. However, tendon degeneration almost always necessitates a certain amount of debridement during arthroscopic repair, which alters tear size and shape. The aim of this study is to question the accuracy of the pre-operative tear size and classification in MRI and its relation to the tear size and type of the debrided tendon during arthroscopic repair. Read More

Insights Imaging 2018 Oct 17;9(5):791-814. Epub 2018 Aug 17.

Department of Radiology, Centro Hospitalar São João, Porto, Portugal.

Ultrasound elastography (USE) is a recent technology that has experienced major developments in the past two decades. The assessment of the main mechanical properties of tissues can be made with this technology by characterisation of their response to stress. This article reviews the two major techniques used in musculoskeletal elastography, compression elastography (CE) and shear-wave elastography (SWE), and evaluates the studies published on major electronic databases that use both techniques in the context of tendon pathology. Read More

Zhongguo Gu Shang 2018 Jul;31(7):612-616

Department of Orthopaedics, the Second Affiliated Hospital of Zhejiang University Shool of Medicine, Hangzhou 310009, Zhejiang, China;

Objective: To explore operative technique and clinical efficacy of tenotomy fixed on distal trochlea under arthroscopy for long head of biceps tendon and rotator cuff tear.

Methods: From June 2015 to November 2016, 23 patients with long head of biceps tendon and rotator cuff tear were treated with tenotomy fixed on distal trochlea under arthroscopy and rotator cuff repair. Among them, including 9 males and 14 females aged from 44 to 71 years old with an average of(56. Read More

Arch Phys Med Rehabil 2019 Feb 2;100(2):336-349.e15. Epub 2018 Aug 2.

Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Objective: To compare the effectiveness of diverse injections in patients with rotator cuff tendinopathy using pairwise and network meta-analysis.

Data Sources: PubMed, EMBASE, Scopus, and Cochrane Library were searched for studies published up to September 31, 2017.

Study Selection: We included all published or unpublished randomized controlled trials (RCTs) comparing diverse injections including corticosteroid, nonsteroidal anti-inflammatory drugs, hyaluronic acid, botulinum toxin, platelet-rich plasma (PRP), and prolotherapy in patients with rotator cuff tendinopathy. Read More

Mater Sociomed 2018 Jun;30(2):131-146

Laboratory of Physiology-Pharmacology, Department of Nursing, Faculty of Human Movement and Quality of Life Sciences, University of Peloponnese, Sparta, Greece.

Introduction: People suffering from tendinopathies exhibit reduced mobility due to the pain caused by the movement of the tendons involved. Recently, shockwave therapy has been used as a treatment option, which is non-invasive, simpler, faster and safer.

Aims: To record the intensity of the pain, the functionality of the upper and lower limbs and quality of life before treatment with shock waves, immediately after the treatment and the 4-week follow-up. Read More

Am J Vet Res 2018 Aug;79(8):836-844

OBJECTIVE To characterize the MRI and histologic features of the supraspinatus tendon in nonlame dogs. ANIMALS 7 cadavers (14 shoulder joints) of nonlame 2-year-old sexually intact male Beagles. PROCEDURES Multiple MRI fluid-sensitive pulse sequences were obtained for both shoulder joints of each cadaver, and the thickness, volume, and signal intensity of each supraspinatus tendon were assessed. Read More

BMC Med Genet 2018 Jul 18;19(1):119. Epub 2018 Jul 18.

Research Division, National Institute of Traumatology and Orthopaedics, Avenida Brasil, 500, Rio de Janeiro, RJ, 20940-070, Brazil.

Background: Tendinopathy pathogenesis is associated with inflammation. Regulatory T (Treg) cells contribute to early tissue repair through an anti-inflammatory action, with the forkhead box P3 (FOXP3) transcription factor being essential for Treg function, and the FC-receptor-like 3 (FCRL3) possibly negatively regulating Treg function. FCRL3 -169T>C and FOXP3 -2383C>T polymorphisms are located near elements that regulate respective genes expression, thus it was deemed relevant to evaluate these polymorphisms as risk factors for tendinopathy development in athletes. Read More

Skeletal Radiol 2019 Feb 7;48(2):245-250. Epub 2018 Jul 7.

Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Objective: To compare the incidence of rotator cuff tears on shoulder MRI in patients who have rotator cuff calcific tendinopathy with that in patients without calcific tendinopathy in a frequency-matched case-control study.

Materials And Methods: Retrospective review shoulder MRIs of 86 patients with rotator cuff calcific tendinopathy and an 86-patient age-, gender-, and laterality-matched control group using frequency matching.

Results: No statistically significant difference (odds ratio: 0. Read More

Yonsei Med J 2018 Jul;59(5):669-676

Department of Preventive Medicine, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.

Purpose: Upper extremity musculoskeletal disorders (UEMDs), such as rotator cuff tear, epicondylitis, and hand osteoarthritis, have a negative impact on quality of life (QOL). In this study, we evaluated the prevalence of rotator cuff tear, lateral and medial epicondylitis, and hand osteoarthritis in the dominant side and the impact of these UEMDs on the disabilities of the arm, shoulder, and hand (DASH) outcome measure, which assesses upper extremity-related QOL.

Materials And Methods: In 2013-2015, 987 participants from rural areas completed a questionnaire and underwent physical examinations, laboratory tests, simple radiographic evaluations of bilateral upper extremities, and magnetic resonance imaging studies of bilateral shoulders. Read More

Front Vet Sci 2018 17;5:98. Epub 2018 May 17.

Veterinary Orthopedic and Sports Medicine Group, Annapolis Junction, MD, United States.

Objective: To report sonographic findings for dogs with a supraspinatus tendinopathy (ST) treated with an ultrasound-guided intratendinous injection of bone marrow aspirate concentrate (BMAC) and platelet-rich plasma (PRP).

Methods: Medical records for dogs diagnosed with an ST and treated with a BMAC-PRP injection were reviewed. Data collected included patient signalment, radiographic findings at the time of initial evaluation, and sonographic findings, including cross-sectional area (CSA), fiber pattern, and echogenicity. Read More

Arthroscopy 2018 Jun;34(6):1976-1978

Vail, Colorado (R.F.L.).

Biological approaches have a promising future in the orthopaedic field because of their potential benefits that include their minimal invasiveness, potential for accelerated healing, and promise for rapid recovery. However, as the initial hype for these therapies starts to fade, it should be replaced by solid basic and clinical science research to tailor each compound to a determined patient/pathology. Blood contains several products that can be both beneficial and detrimental for every specific tissue, and therefore a one-fits-all approach should be avoided. Read More

Shoulder Elbow 2018 Jul 5;10(3):170-178. Epub 2017 Jun 5.

Orthopaedic Research Institute, St George Hospital Campus, Sydney, NSW, Australia.

Background: Subacromial corticosteroid injections are frequently performed for pain associated with supraspinatus tendinopathy. Glucose prolotherapy has been used clinically for multiple tendinopathies and is hypothesized to be an alternate injection therapy for supraspinatus tendinopathy.

Methods: A prospective, randomized, double blinded clinical trial was conducted. Read More

Pain Res Manag 2018 25;2018:8286190. Epub 2018 Mar 25.

Department of Anesthesiology and Pain Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: Rotator cuff tendinopathy is a primary cause of shoulder pain and dysfunction. Several effective nonsurgical treatment methods have been described for chronic rotator cuff tendinopathy. Prolotherapy with polydeoxyribonucleotide (PDRN), which consists of active deoxyribonucleotide polymers that stimulate tissue repair, is a nonsurgical regenerative injection that may be a viable treatment option. Read More