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J Otolaryngol Head Neck Surg 2019 Feb 4;48(1). Epub 2019 Feb 4.

Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.

Background: Malignancies occur in approximately 1:1000 pregnancies; the most common being breast (46%) and hematological (18%) malignancies. Oral cancers account for only 2% of all cancers in pregnant women, and there are no standard guidelines for the treatment of oral cancer during pregnancy.

Methods: Between 2007 and 2014, our department managed 1109 patients with oral cancers; four (0. Read More

Gan To Kagaku Ryoho 2018 Dec;45(13):2135-2137

Dept. of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine.

Leeches have been used for medical treatment for at least 2,500 years. Plastic surgeons have recently begun to use leeches to reduce venous congestion after flap reconstruction. However, few reports of leech use in the oral region have been published. Read More

Cochrane Database Syst Rev 2018 12 24;12:CD006205. Epub 2018 Dec 24.

School of Dentistry, The University of Western Australia, 17 Monash Avenue, Nedlands, Western Australia, Australia, 6009.

Background: Surgery is an important part of the management of oral cavity cancer with regard to both the removal of the primary tumour and removal of lymph nodes in the neck. Surgery is less frequently used in oropharyngeal cancer. Surgery alone may be treatment for early-stage disease or surgery may be used in combination with radiotherapy, chemotherapy and immunotherapy/biotherapy. Read More

Int J Surg Pathol 2018 Nov 27:1066896918814304. Epub 2018 Nov 27.

1 Aichi Gakuin University, Nagoya, Japan.

Adenoid cystic carcinoma is one of the most common salivary gland malignancies with poor long-term prognosis, but the coexistence of sialoliths is extraordinarily rare. In this article, we report a case of 30-year-old woman with a history of submandibular area swelling with intermittent pain increasing during mealtimes that had led her attending physician to diagnose a sialolith in the left submandibular gland on a radiograph 10 years before. However, the surgical specimen proved to be an adenoid cystic carcinoma accompanied with a sialolith. Read More

Curr Probl Cancer 2018 Nov 12. Epub 2018 Nov 12.

Hospital Virgen de las Nieves, Granada, Spain.

Purpose: The main aim of the present study is to analyze the behavior of squamous cell carcinoma (SCC) of maxillary gingiva, alveolus, and hard palate and to determine the utility of selective neck dissection in clinically N0 patients at early stages.

Material And Method: Twenty-nine previously untreated patients with SCC of maxillary gingiva, alveolus, and hard palate were diagnosed and treated with at least a tumorectomy and selective neck dissection at HUVN and included in the study.

Results: A total of 34. Read More

World J Surg Oncol 2018 Nov 8;16(1):219. Epub 2018 Nov 8.

Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India.

Background: The lymphatic spread from the cancers of the oral cavity follows an orderly progression and involvement of lower nodes without involvement of upper nodes and skip metastasis is rare. Selective neck dissections are increasingly being performed for node-positive patients; however, in node-negative patients the options of wait and watch, prophylactic radiotherapy, and prophylactic elective node dissections are debated. Quality of life and shoulder functions are important to choose the appropriate therapeutic modality. Read More

Ned Tijdschr Tandheelkd 2018 Oct;125(10):517-523

A 48-year-old man was referred for an evaluation of deviations in the pigmentation of the lower lip, intra-oral swelling and persistent numbness of the sensory area of the left mental nerve. In 2011, the diagnosis lentigo maligna of the lower lip was missed by histopathology of a biopsy performed elsewhere. In 2016, the numbness of the lower lip and chin was diagnosed by a neurologist as numb chin of unknown cause. Read More

Clin Oral Investig 2018 Sep 21. Epub 2018 Sep 21.

Department of Oral and Maxillofacial Surgery, Kothiwal Dental College and Research Center, Moradabad, UP, 243001, India.

Objective: To assess the correlation of skip metastases associated with increase in tumor thickness and size of the tumor.

Material And Methods: A retrospective analysis was carried out from August 2009 to August 2015. In this study, a total number of 33 carcinoma tongue patients having T1, T2, and T3 sizes with N0 and N+ clinical necks who were treated by supraomohyoid neck dissection, extended supraomohyoid neck dissection, and modified radical neck dissection were analyzed. Read More

J Coll Physicians Surg Pak 2018 Jun;28(6):S125-S127

Sardar Begum Dental Hospital, Peshawar.

Deltopectoral flap is a widely used flap in reconstruction surgery. A patient presented with extra-oral solitary swelling on the right lower jaw and an intra-oral exophytic growth located along the lower border of right mandibular jaw. Incisional biopsy was done which revealed moderately-differentiated squamous cell carcinoma. Read More

Acta Otorrinolaringol Esp 2018 May 11. Epub 2018 May 11.

Hospital Virgen de las Nieves, Granada, Spain.

Aim: The main aim of the present report is to study the behavior of SCC of the floor of the mouth.

Materials And Method: A retrospective analysis was conducted using the records of patients diagnosed with squamous cell carcinoma of the floor of the mouth between 2000 and 2012 in the HUVN. Ninety-three patients with squamous cell carcinoma of the floor of the mouth treated with tumourectomy and selective neck dissection were included in the study. Read More

Microsurgery 2018 Oct 2;38(7):795-798. Epub 2018 May 2.

Department of Plastic, Reconstructive and Maxillo-Facial Surgery, and Burn Unity, Centro Hospitalar de São João, Porto Medical School, Porto, Portugal.

Facial artery perforator flaps have been recently reported by different authors for perioral, nasal alar and cheek defects, but not for intraoral reconstruction. We have extended the use of the facial artery perforator flap in a 56-year-old man with a squamous cell carcinoma of left mouth floor, who was submitted to tumor resection with marginal mandibulectomy and left supraomohyoid neck dissection. The flap was designed according to the size of the defect (5 × 3 cm), centered on the perforator to create a symmetric flap and was tunnelled intraorally by means of a 90° rotation. Read More

Acta Otorrinolaringol Esp 2018 Jul - Aug;69(4):226-230. Epub 2018 Mar 16.

Department of Otorhinolaryngology-Head and Neck Surgery, Liaquat National Hospital & Medical College, Karachi, Pakistan.

Objective: To identify the significant predictors of locoregional recurrence in early stage squamous cell carcinoma (SCC) of buccal mucosa with pathologically clear surgical margins and negative neck.

Method: Seventy-three patients who underwent per oral wide excision and supraomohyoid neck dissection for early stage buccal SCC with clear surgical margins (>5mm margins each) and negative neck (N0) were included. None of the patients received postoperative radiotherapy or chemotherapy. Read More

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Feb;53(2):73-78

Department of Oral and Maxillofacial Surgery, Weifang People's Hospital, Weifang Shandong 261000, China.

To investigate the different pattern of neck lymph node metastasis, the choice of surgical methods and prognosis in early tongue squamous cell carcinoma. A total of 157 patients with early oral tongue squamous cell carcinoma were included in this study. Statistical analysis was performed to identify the pattern of lymph node metastasis, to determine the best surgical procedure and to analyze the prognosis. Read More

J Dent Anesth Pain Med 2017 Dec 28;17(4):313-316. Epub 2017 Dec 28.

Department of Dental Anesthesia and Pain Medicine, Pusan National University Dental Hospital, Dental Research Institute, Yangsan, Korea.

Mask ventilation, the first step in airway management, is a rescue technique when endotracheal intubation fails. Therefore, ordinary airway management for the induction of general anesthesia cannot be conducted in the situation of difficult mask ventilation (DMV). Here, we report a case of awake intubation in a patient with a huge orocutaneous fistula. Read More

J Oral Maxillofac Surg 2018 Mar 5;76(3):647-655. Epub 2017 Aug 5.

DMD Student, University of Colorado, School of Dental Medicine, Denver, CO.

Purpose: To estimate the clinical and functional results of patients who underwent distinctive types of neck dissection, with particular emphasis on shoulder function, rate of recurrence, and quality of life in patients with N0 neck.

Materials And Methods: A randomized clinical trial was conducted from August 2014 to March 2017 in which 20 adult patients with T1 to T3 lesions of the oral cavity and N0 neck were included. Patients were randomly allocated to group I (n = 10; selective neck dissection) or group II (n = 10; superselective neck dissection). Read More

Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Jul 10;124(1):32-36. Epub 2017 Mar 10.

Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Objective: Analysis of the incidence and clinical relevance of neck failure after elective neck dissection (END) in patients with oral squamous cell carcinoma (OSCC).

Study Design: A retrospective study of 188 patients with OSCC without cervical lymph node metastases was conducted; these patients had undergone END from 2005 to 2015. The most common primary tumor location was lower gingiva, followed by tongue. Read More

Hua Xi Kou Qiang Yi Xue Za Zhi 2016 Aug;34(4):408-413

Dept. of Oral and Maxillofacial Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.

Objective: This study aimed to investigate the value of carbon nanoparticles as lymph node tracers in neck dissection for cN0 lingual squamous cell carcinoma patients.

Methods: Ninety-six patients with cN0 lingual squamous cell carcinoma were recruited to undergo surgical treatment were randomly divided into two groups, namely, the carbon nanoparticle-labeled group (the experimental group, 50 cases) and the control group (46 cases). Carbon nanoparticle suspension was injected into the submucosal layer around the site of the primary tumor at three or four points (0. Read More

Laryngoscope 2017 09 8;127(9):2070-2073. Epub 2017 Mar 8.

Department of Otolaryngology-Head and Neck Surgery, Tulane University School of Medicine, New Orleans, Louisiana.

Objectives/hypothesis: Unlike lymphadenectomy at other sites, there is no discrete lymph node count defining an adequate neck dissection. The purpose of this study was to determine the minimum lymph node yield (LNY) of an elective level I-III neck dissection required to reliably capture any positive nodes present in these nodal basins.

Study Design: Retrospective single-institution analysis. Read More

Dentomaxillofac Radiol 2017 Mar 17;46(3):20160345. Epub 2017 Feb 17.

1 Department of Oral Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Stomatology, Shanghai, China.

Objectives: To assess the usefulness of contrast-enhanced ultrasound (CEUS) with peritumoral injection of microbubble contrast agent for detecting the sentinel lymph nodes for oral tongue carcinoma.

Methods: The study was carried out on 12 patients with T1-2cN0 oral tongue cancer. A radical resection of the primary disease was planned; a modified radical supraomohyoid neck dissection was reserved for patients with larger lesions (T2, n = 8). Read More

Case Rep Dent 2017 17;2017:7495695. Epub 2017 Dec 17.

Department of Oral Medicine & Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Sarcomatoid carcinoma (SC) is a rare variant of squamous cell carcinoma which is characterized by a dysplastic epithelial component and a stromal element with invasive fusiform or spindle-shaped cells. The clinical and histopathologic characteristics make it very difficult to distinguish SC from epithelioid sarcoma (ES). We present a case of a 51-year-old man with a soft tissue mass in the oral cavity diagnosed as proximal variant of epithelioid sarcoma on incisional biopsy. Read More

ANZ J Surg 2017 Jan 23;87(1-2):65-69. Epub 2016 Nov 23.

Head and Neck Cancer Service, Crown Princess Mary Cancer Centre, Sydney, New South Wales, Australia.

Background: Sentinel lymph node biopsy (SLNB) has become an alternative option to elective neck dissection (END) for early oral cavity squamous cell carcinoma (OCSCC) outside of Australia. We sought to assess the technical feasibility of SLNB and validate its accuracy against that of END in an Australian setting.

Methods: We performed a prospective cohort study consisting of 30 consecutive patients with cT N OCSCC referred to the Head and Neck Cancer Service, Westmead Hospital, Sydney, between 2011 and 2014. Read More

J Oral Maxillofac Surg 2017 Apr 28;75(4):839-849. Epub 2016 Sep 28.

Medical Psychologist and Professor, Department of Medical Psychology, Ruhr University of Bochum, Bochum, Germany.

Purpose: In this study of patients with oral squamous cell carcinoma, the authors sought to clarify the functional and psychosocial harms of neck dissection (ND), which lessens quality of life.

Materials And Methods: The study included questionnaire responses from patients with oral squamous cell carcinoma (n = 1,652) and clinicians (n = 1,489), as collected in the DÖSAK Rehab Study. Psychosocial and functional factors were assessed. Read More

Ear Nose Throat J 2016 Sep;95(9):E15-7

Department of Otolaryngology, Oita University, Idaigaoka hasama-machi, Yufu, Oita, Japan 879-5593.

This report describes a salivary duct carcinoma (SDC) arising from the extraglandular portion of the Stensen duct. The patient was a 56-year-old man who presented with a palpable, elastic, hard mass without tenderness in the right cheek. Computed tomography revealed a tumor of the extraglandular portion of the Stensen duct. Read More

J Craniomaxillofac Surg 2016 Oct 6;44(10):1737-1742. Epub 2016 Aug 6.

Department of Oral and Maxillofacial Surgery, University of Technology Munich, Ismaninger Str. 22, 81675 Munich, Germany.

Introduction: A supraomohyoid neck dissection (SOHND) is part of the surgical management of patients with oral cancer, even in the absence of clinical or radiographic evidence of neck disease. We have investigated a standardized approach to the management of cervical lymph nodes, in patients with a primary oral cancer. A modified surgical technique has been presented and a clinical algorithm has been described and evaluated. Read More

Srp Arh Celok Lek 2016 Sep-Oct;144(9-10):531-4

Introduction: Mucoepidermoid carcinoma, compared to other tumors of salivary glands, occurs in 5–10% of cases. Histopathologically, it is divided into a well differentiated tumor that is of low-grade of malignancy, and a medium and poorly differentiated tumor of high grade of malignancy. Central mucoepidermoid carcinoma (CMEC) of the mandible was firstly described by Lepp in 1936, on a 66-year-old female patient. Read More

Yonago Acta Med 2016 Jun 29;59(2):159-62. Epub 2016 Jun 29.

†Division of Otolaryngology, Head and Neck Surgery, Department of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.

Background: Recipient vessel selection in head and neck reconstruction using free flap transfers has to be standardized. However, the recipient vessel selection based on the type of neck dissection has yet to be investigated. We describe the relationship between the type of neck dissection and recipient vessel. Read More

Oncol Lett 2016 May 7;11(5):3493-3500. Epub 2016 Apr 7.

Department of Oral and Maxillofacial Surgery, Virgen Del Rocío University Hospital, University of Seville, Seville, Seville 41013, Spain.

The present study aimed to describe the techniques used and the results obtained with the infrahyoid flap for the reconstruction of medium-sized oropharyngeal defects following resection for advanced squamous cell cancer. During a period of 1 year, six patients with oropharyngeal defects were reconstructed using the infrahyoid flap. The tumor characteristics, location and size of the defect, resective and reconstructive techniques employed and the complications and outcomes of the speech and swallowing functions, as identified in the follow-up visits every 3 months, were evaluated. Read More

Int Arch Otorhinolaryngol 2016 Apr 7;20(2):138-44. Epub 2016 Mar 7.

Department of Head and Neck Surgery and Otorhinolaryngology, AC Camargo Cancer Center, São Paulo, SP, Brazil.

Introduction There has been a significant increase in concern towards improving aesthetic and functional outcomes without compromising the oncologic effectiveness in head and neck surgery. In this subset, endoscope-assisted and robotic procedures allowed the development of new approaches to the neck, including the retroauricular access, which is now routinely used, especially in Korea. Objectives This study aims to provide a descriptive analysis of our initial experience with retroauricular endoscope-assisted approach assessing feasibility, safety, and aesthetic results. Read More

J Laryngol Otol 2016 May;130(5):474-7

Otorhinolaryngology Research Center,Otolaryngology Department,Tehran University of Medical Sciences,Iran.

Objective: The present study was conducted to determine the rate of level IV lymph node involvement among node-negative (N0) necks in patients with squamous cell carcinoma of the tongue.

Methods: The study comprised 32 patients with squamous cell carcinoma of the tongue, with tumour-node-metastasis staging of T1-3N0M0, who were admitted to the Otolaryngology Department at Tehran University of Medical Sciences from March 2012 to March 2014. After a complete diagnostic evaluation, wide primary tumour excision (with 1. Read More

World Neurosurg 2016 Jun 4;90:698.e7-698.e11. Epub 2016 Feb 4.

Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:

Background: The diagnosis of extraneural metastasis from glioblastoma is usually based on the histopathology and immunohistochemical staining of a tumor specimen. Information regarding the molecular features of glioblastoma and optimal treatment strategies for extraneural metastasis is limited.

Case Description: A 58-year-old woman with a glioblastoma located in the left temporal lobe underwent resection followed by radiotherapy plus concomitant and adjuvant temozolomide. Read More

Surg Endosc 2016 06 29;30(6):2315-20. Epub 2015 Dec 29.

Department of Minimal Access Surgery, Bharat Cancer Hospital and Research Institute, Surat, India.

Background And Objective: To study the feasibility of a total endoscopic technique for selective neck dissection in oral cancers and to compare the technique with conventional open technique with a long cervical scar.

Methods: We included patients with early intraorally resectable squamous carcinomas and excluded patients whose primary lesion required reconstruction with microvascular flaps. We compared the following intraoperative parameters: cumulative length of the incision(s), duration of surgery, estimated blood loss, and intraoperative complications. Read More

Medicine (Baltimore) 2015 Nov;94(44):e1704

From the Department of Nuclear Medicine, Yeungnam University Hospital, Daegu, Korea.

Malignant tracheal tumors (primary and secondary) are rare and benign tumors of the tracheobronchial tree are also rare. Few reports have been issued on the F-fluorodeoxyglucose (F-FDG) positron emission tomography (PET) findings of tracheal tumors or benign nontumorous tracheal lesions, which have been mainly studied by computed tomography (CT). The author reports 2 cases of intratracheal lesions with quite different F-FDG PET/CT findings. Read More

Plast Reconstr Surg Glob Open 2015 Sep 4;3(9):e504. Epub 2015 Sep 4.

First Department of Oral and Maxillofacial Surgery, Osaka University Dental Hospital, Osaka University Graduate School of Dentistry, Osaka, Japan.

Background: Modified radical neck dissection (mRND) [preserving the sternocleidomastoid muscle (SCM) and the spinal accessory nerve] and supraomohyoid neck dissection have become common surgical procedures for treating head and neck cancer. Postoperative severe asymmetry of the neck and severe atrophy of the SCM, however, have been demonstrated.

Methods: Using computed tomographic images, cross-sectional areas of the SCMs were measured in 99 patients with carcinoma of the oral cavity who underwent unilateral mRND or supraomohyoid neck dissection. Read More

Clin Otolaryngol 2016 Jun 4;41(3):228-33. Epub 2016 Feb 4.

Department ofOtorhinolaryngology and Head and Neck Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.

Objectives: To examine health utilities in patients with cT1-2 oral cavity squamous cell carcinoma following different diagnostic and treatment modalities for the neck and to investigate the relation between shoulder morbidity and health utility.

Design: Cross-sectional survey.

Setting: Two Dutch hospitals. Read More

Int J Oral Maxillofac Surg 2015 Oct 29;44(10):1218-24. Epub 2015 Jun 29.

Department of Stomatology and Maxillofacial Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

The objective was to investigate factors influencing internal jugular vein stenosis or occlusion after neck dissection, including the reconstructive procedure. The subjects were 73 patients (81 veins) who underwent a modified radical neck dissection, in which the internal jugular vein was preserved, or an extended supraomohyoid neck dissection (E-SOHND). All procedures were performed by the same surgeon. Read More

J Oral Maxillofac Surg 2015 Oct 20;73(10):2066.e1-7. Epub 2015 Jun 20.

Professor and Chairman, Division of Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, Fukuoka, Japan.

Purpose: This report describes a case that required emergency cricothyroidotomy for an upper airway obstruction owing to laryngeal edema after asynchronous bilateral neck dissections.

Patient And Methods: A 57-year-old man was diagnosed with multicentric squamous cell carcinoma of the tongue (T1 and 2N0M0), and partial glossectomy with primary closure was performed. Three months after surgery, secondary metastases in the right cervical lymph nodes were detected, and a right radical neck dissection was performed. Read More

Am J Case Rep 2015 Jul 1;16:415-9. Epub 2015 Jul 1.

Department of Surgical Oncology, Head and Neck Surgery, Westmead Hospital, Sydney, Australia.

Background: Ameloblastic carcinoma secondary type is an extremely rare and aggressive odontogenic neoplasm that exhibits histological features of malignancy in primary and metastatic sites. It arises through carcinomatous de-differentiation of a pre-existing ameloblastoma or odontogenic cyst, typically following repeated treatments and recurrences of the benign precursor neoplasm. Identification of an ameloblastic carcinoma, secondary type presenting with histologic features of malignant transformation from an earlier untreated benign lesion remains a rarity. Read More

J Int Soc Prev Community Dent 2015 Mar-Apr;5(2):131-40

Department of Oral and Maxillofacial Surgery, RVS Hospital, RVS Nagar, Tirupati road, Chittoor, Andhra Pradesh, India.

Background: To evaluate the effectiveness of the supraomohyoid neck dissection in clinically N0 neck patients with squamous cell carcinoma of buccal mucosa and gingivobuccal sulcus.

Materials And Methods: This was a prospective study of five patients with squamous cell carcinoma of gingivobuccal mucosa of oral cavity with clinically N0 neck, conducted over a period of 2 years from July 2007 to Oct 2009 in the Department of Oral and Maxillofacial Surgery, Narayana Dental College and Hospital. The study was conducted in patients irrespective of age, sex, size, thickness, and type of differentiation of the lesion. Read More

Shanghai Kou Qiang Yi Xue 2015 Apr;24(2):219-23

Department of Oral and Maxillofacial-Head and Neck Surgery, Anhui Provincial Hospital, Anhui Medical University. Hefei 230001, Anhui Province,

Purpose: To study the medium or long-term survival rates of different methods used in the treatment of advanced squamous cell carcinoma of the maxillary sinus (SCMS).

Methods: Patients were treated by one of the following methods: 231 patients were treated with induction chemotherapy, followed by radical resection and radiotherapy (CSR); 128 patients were treated with preoperative irradiation (RS), and 87 patients underwent adjuvant radiotherapy (RSR). A total of 446 cases of SCMS from June 1985 to December 2008 were managed with unscheduled application of the above 3 kinds of treatment options. Read More

Int J Clin Exp Med 2015 15;8(1):1296-300. Epub 2015 Jan 15.

Department of Oral and Maxillofacial-Head and Neck Surgery, Beijing Stomatological Hospital, Capital Medical University Beijing, China.

Surgical site infection (SSI) is a common complication followed neck dissection and dead space is a common reason of SSI. The present study is aimed to explore whether the sternocleidomastoid muscle (SCM) flap transposition to repair the dead space in level II of neck could decrease the postoperative SSI in patients with oral squamous cell carcinoma (OSCC) underwent supraomohyoid neck dissection (SOND). Ninety-six patients with cT2-3N0 OSCC who underwent extended resection of primary cancer combined SOND and reconstructed with free flap from March 2011 to October 2014 in our department were included. Read More

Cancer Epidemiol 2015 Jun 13;39(3):360-6. Epub 2015 Mar 13.

Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Sri Lanka. Electronic address:

The clinical outcome of patients with OSCC is assessed based on TNM system and currently it is the most reliable indicator on which therapeutic decisions are made. The patients with advanced disease are managed with combined treatment modalities. The aim of this retrospective study was to identify the factors which influence survival of patients with OSCC in Sri Lanka. Read More

Clin Med Insights Ear Nose Throat 2015 9;8:1-6. Epub 2015 Feb 9.

Department of Pathology, Faculty of Medicine, Cairo University, Egypt.

Objectives: To evaluate the effectiveness of selective neck dissection of sublevel IIa and level III in cases of glottis and supraglottic laryngeal carcinoma in the absence of lymph node metastasis and to show if there is value in dissecting the sublevel IIb or level IV in these cases.

Patients And Methods: Twenty-five patients with N0 glottic or supraglottic cancer were subjected to unilateral or bilateral selective neck dissection according to the site and the extent of the tumor, and the specimens were histopathologically examined for metastasis.

Results: Twenty-five patients (23 males and 2 females) with mean age of 55. Read More

Turk Arch Otorhinolaryngol 2015 Mar 1;53(1):23-25. Epub 2015 Mar 1.

Department of Otorhinolaryngology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.

Objective: To date, the management of the neck in early stage lower lip cancers remains controversial. The aim of this study is to investigate if prophylactic neck dissection is necessary in early stage lower lip cancers.

Methods: Charts of 11 patients who underwent surgery of the primary site and neck because of T1-2N0 lower lip cancer between 1997 and 2011 were retrospectively examined. Read More

Indian J Otolaryngol Head Neck Surg 2015 Mar 22;67(Suppl 1):138-40. Epub 2014 Nov 22.

Department of Orthopedics, Lilavati Hospital and Research Centre, Mumbai, India.

Current surgical treatment for oral cancers includes wide surgical excision of the primary lesion with appropriate neck dissection. Although tumor metastasis to the gland is uncommon, submandibular glands are frequently excised as a part of neck dissection because of their proximity to the primary lesion and afferent lymph nodes. Herein, we have retrospectively investigated the rate of involvement of submandibular glands in oral cavity tumors, and discussed the feasibility about resection of the submandibular glands. Read More

JAMA Otolaryngol Head Neck Surg 2014 Dec;140(12):1191-7

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea.

Importance: Robot-assisted neck dissection (RAND) for the management of regional metastases is a recently developed technique in the field of head and neck cancer that uses a robotic surgical system. This is the first report that estimates the learning curve for RAND.

Objectives: To evaluate a learning curve for RAND according to the types of neck dissection and report clinical outcomes. Read More

Hippokratia 2014 Apr;18(2):120-4

Department of Otorhinolaryngology, Colţea Clinical Hospital, Carol Davila University of Medicine and Pharmacy.

Objectives: The presence of neck metastases represents one of the most important prognostic factors for carcinomas of the anterior tongue, the five-year survival rate being under 20% in patients with regional metastases. The aim of this study was to demonstrate the efficacy of prophylactic selective neck dissection in patients without detectable nodal metastases.

Materials And Methods: A matched case-control study with prospective follow up was conducted in ENT Department of Coltea Clinical Hospital for 86 patients with T1-T2N0 stage carcinoma of the anterior tongue surgically treated between January 2000 and January 2005 with or without concurrent selective supraomohyoid neck dissection (SND). Read More

J Craniomaxillofac Surg 2014 Dec 6;42(8):1885-90. Epub 2014 Aug 6.

Department of Oral and Maxillofacial Surgery, School of Stomatology, Peking University, Beijing 100081, China.

Background: To assess the prognosis and morbidity between supraomohyoid neck dissection (SOND) and modified radical neck dissection (MRND) for oral squamous cell carcinoma (OSCC) in patients with a clinically node-negative neck (cN0).

Patients And Methods: This prospective randomized study began in June 1999, and patient accrual concluded in May 2010. The cN0 neck was confirmed on clinical palpation by senior doctors. Read More

J Oral Maxillofac Surg 2014 Nov 29;72(11):2344-50. Epub 2014 May 29.

Professor, Department of Oral and Maxillofacial Surgery, School of Stomatology, Peking University, Beijing, China. Electronic address:

Purpose: Buccal mucosa squamous cell carcinoma (BSCC) is considered a rare and aggressive malignancy that has a high rate of locoregional recurrence. The aim of this study was to analyze the outcome of surgical therapy as a treatment for BSCC in a North Chinese population over a period of 14 years.

Materials And Methods: A retrospective study was performed by reviewing the records and pathologies of 168 patients with BSCC who were treated at the Department of Oral and Maxillofacial Surgery, Stomatological Hospital, Peking University, from June 1999 to September 2013. Read More

Laryngoscope 2015 Jan 14;125(1):128-33. Epub 2014 Jul 14.

Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Taipei, Taiwan; Head and Neck Oncology Group, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Taipei, Taiwan.

Objectives/hypothesis: The benefits of elective neck dissection (END) in early-stage tongue cancer have been widely discussed but are still controversial regarding early-stage buccal cancer. In this study, we evaluate the role of END and the treatment outcome in early-stage buccal cancer in an areca-quid endemic area.

Study Design: Retrospective case-control study. Read More

Bull Tokyo Dent Coll 2014 ;55(1):49-54

Department of Stomatology, Tokyo Metropolitan Ohtsuka Hospital.

Here we describe two patients in whom prostheses were applied for flap protection after buccal mucosal incision. In the first case, the patient was a 65-year-old man with a diagnosis of buccal mucosa squamous cell carcinoma (T2N0M0). Left buccal mucosa squamous cell tumor resection and dermoplasty were performed, followed by alveolar ridge augmentation and buccal mucosal graft in the scar area. Read More