3,828 results match your criteria Sunburn


Increasing incidence of lentigo maligna and lentigo maligna melanoma in Catalonia.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Hospital Universitari Arnau de Vilanova, University of Lleida, IRBLleida, Lleida & CIBERONC, Lleida, Spain.

Background: Recent epidemiological studies suggest that past data where superficial spreading melanoma was by far the most common subtype of melanoma may not reflect current patterns of sun exposure or other risk factors more involved in other subtypes of melanoma as lentigo maligna (LM) or lentigo maligna melanoma (LMM).

Methods: In order to measure the current situation in our country, all cases of LM and LMM diagnosed in 23 hospitals in Catalonia, from 2000 to 2007, were recorded.

Results: Although for the global period LM/LMM represented only 8. Read More

View Article
December 2018

Modifiable Risk-factors for Keratinocyte Cancers in Australia: A Case-control Study.

Acta Derm Venereol 2018 Dec 13. Epub 2018 Dec 13.

Department of Clinical Epidemiology and Applied Biostatistics, University Hospital Tübingen, DE-72076 Tübingen, Germany.

Keratinocyte cancer (KC) is the most common malignancy in Caucasians. The incidence of KC has increased over the past 40 years. This case-control study investigated the environmental and host risk-factors responsible for development of KC in Australia's high-risk population. Read More

View Article
December 2018
1 Read

Do ultraviolet photos increase sun safe behavior expectations via fear? A randomized controlled trial in a sample of U.S. adults.

J Behav Med 2018 Dec 6. Epub 2018 Dec 6.

Huntsman Cancer Institute, University of Utah, Salt Lake City, USA.

Ultraviolet (UV) photos reveal the world in a different light spectrum, including damage that is caused by UV light. In the context of skin cancer control, UV photos have the potential to communicate fear because they reveal underlying skin damage. U. Read More

View Article
December 2018

Severe Photo Toxicity Recalled by Docetaxel.

Case Rep Oncol 2018 Sep-Dec;11(3):751-755. Epub 2018 Nov 12.

Capio S: t Görans Hospital, Department of Clinical Oncology, Stockholm, Sweden.

Photo-recall phenomenon is a rarely recognized adverse event of chemotherapeutic agents. The physiopathology of this entity is unclear. We have reported a 56-year old breast cancer patient with severe photo toxicity recalled 5 months after the initial sunburn by one course of adjuvant docetaxel treatment. Read More

View Article
November 2018
3 Reads

Adult UVR exposure changes with life stage - a 14-year follow-up study using personal electronic UVR dosimeters.

Photochem Photobiol Sci 2018 Dec 4. Epub 2018 Dec 4.

Department of Dermatology, Frederiksberg and Bispebjerg Hospitals, University of Copenhagen, Copenhagen, Denmark.

Over a period spanning 14 years (1999-2001, 2006 and 2012), 31 volunteers participated in sun behaviour studies with the same protocol wearing a personal, electronic wrist-borne UVR dosimeter and completed sun exposure diaries resulting in a total of 15 946 measurements days (126 days per person per year). The participants individually maintained their UVR dose level and behaviour over the years. No statistically significant differences were seen from year to year in the "estimated annual UVR dose", the "mean UVR dose per day", the "mean percentage of ambient UVR", "days sunbathing to get a tan", "days with intermittent exposure" or in "sunburn episodes". Read More

View Article
December 2018
2 Reads

A Mobile Technology Intervention With Ultraviolet Radiation Dosimeters and Smartphone Apps for Skin Cancer Prevention in Young Adults: Randomized Controlled Trial.

JMIR Mhealth Uhealth 2018 Nov 28;6(11):e199. Epub 2018 Nov 28.

Institute of Health and Biomedical Innovation, School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.

Background: Skin cancer is the most prevalent and most preventable cancer in Australia. Despite Australia's long-running public health campaigns, young Australian adults continue to report high levels of ultraviolet radiation (UVR) exposure and frequent sunburns. Young people are now increasingly turning away from traditional media, such as newspapers and TV, favoring Web-based streaming, which is challenging the health care sector to develop new ways to reach this group with targeted, personalized health promotion messages. Read More

View Article
November 2018

Severe vemurafenib-induced photosensitivity in a 6-year-old boy.

Pediatr Dermatol 2018 Nov 26. Epub 2018 Nov 26.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Vemurafenib, a selective BRAF kinase inhibitor, has been found to induce several cutaneous adverse effects, ranging from a keratosis pilaris-like reaction to squamous cell carcinoma. While photosensitivity has been well described as one of these manifestations, we report a case of a 6-year-old boy on vemurafenib who developed a severe blistering sunburn after only two 30-minute episodes of sun exposure. A brief review of other common cutaneous adverse effects of vemurafenib is also provided. Read More

View Article
November 2018
1 Read

Risk Perception Plays Minimal Role in Sun Exposure Behaviours.

J Cancer Educ 2018 Nov 20. Epub 2018 Nov 20.

The Skin Hospital (branch of the Skin & Cancer Foundation Australia), Sydney, Australia.

Despite decades of public health campaigns, tanning and sunburn still occur at unacceptably high rates. Skin cancer prevention campaigns predominately focus on increasing awareness of the risk of excessive sun exposure. This study sought to assess the efficacy of this approach, by interrogating correlations between risk perception and sun exposure behaviour. Read More

View Article
November 2018
2 Reads

Inhibitory effect of Carnosol on UVB-induced inflammation via inhibition of STAT3.

Arch Pharm Res 2018 Nov 15. Epub 2018 Nov 15.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 361-951, Republic of Korea.

Ultraviolet B (UVB) irradiation causes sunburn, inflammatory responses, dysregulation of immune function, oxidative stress, DNA damage and photocarcinogenesis on skin. Rosemary (Rosmarinus officinalis L.) has been reported to inhibit inflammation. Read More

View Article
November 2018

The Lipid Mediator Resolvin D1 Reduces the Skin Inflammation and Oxidative Stress Induced by UV Irradiation in Hairless Mice.

Front Pharmacol 2018 31;9:1242. Epub 2018 Oct 31.

Laboratory of Oxidative Stress and Inflammation, Department of Pharmaceutical Sciences, Londrina State University, Londrina, Brazil.

UV irradiation-induced oxidative stress and inflammation contribute to the development of skin diseases. Therefore, targeting oxidative stress and inflammation might contribute to reduce skin diseases. Resolvin D1 (RvD1) is a bioactive metabolite generated during inflammation to actively orchestrate the resolution of inflammation. Read More

View Article
October 2018

Public Health Implications of Google Searches for Sunscreen, Sunburn, Skin Cancer, and Melanoma in the United States.

Am J Health Promot 2018 Nov 14:890117118811754. Epub 2018 Nov 14.

2 Department of Dermatology and Population Health Sciences, University of Utah, Salt Lake City, UT, USA.

Purpose:: Google Trends (GT) offers insights into public interests and behaviors and holds potential for guiding public health campaigns. We evaluated trends in US searches for sunscreen, sunburn, skin cancer, and melanoma and their relationships with melanoma outcomes.

Design:: Google Trends was queried for US search volumes from 2004 to 2017. Read More

View Article
November 2018

Hell's itch due to sunburn.

J Travel Med 2018 Nov 13. Epub 2018 Nov 13.

University of Edinburgh, United Kingdom.

View Article
November 2018

Sunburn Recall Reaction and Mucositis Secondary to Methotrexate Toxicity.

Skinmed 2018 9;16(5):340-341. Epub 2018 Nov 9.

School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

A 59-year-old Native American female presented with a 4-day history of malaise, abdominal pain, nausea, jaundice, and a "sunburn-like rash" on the upper chest and back despite lack of recent sun exposure (Figure 1). Medical history was significant for a twenty-year history of universal vitiligo and a five-year history of rheumatoid arthritis (RA) treated with methotrexate (MTX), adalimumab, prednisone, and naproxen sodium. Cutaneous examination revealed hemorrhagic crusting of upper and lower lips (Figure 2), scleral icterus, diffuse jaundice of the skin, and well-demarcated erythematous patches on mid-upper back and anterior neck. Read More

View Article
November 2018
14 Reads

Patient knowledge of FDA-mandated sunscreen labeling terminology: A cross-sectional survey.

Photodermatol Photoimmunol Photomed 2018 Nov 1. Epub 2018 Nov 1.

Ronald O. Perelman Department of Dermatology, NYU School of Medicine, New York City, New York.

Background: Insufficient understanding of sunscreen labeling terminology is a barrier to effective use. The Food and Drug Administration (FDA) issued the "final rule" on sunscreen labeling in 2011, in an effort to promote effective usage. However, relatively little is known about patient knowledge of sunscreen labeling terminology. Read More

View Article
November 2018

Association between phenotypic characteristics and melanoma in a large prospective cohort study.

J Invest Dermatol 2018 Oct 24. Epub 2018 Oct 24.

Department of Population Health, QIMR Berghofer Medical Research Institute, Queensland, Australia; School of Public Health, University of Queensland, Queensland, Australia. Electronic address:

To delineate causal pathways for melanoma, it is essential to derive unbiased estimates of risk. Extant knowledge derives largely from case-control studies with potential for bias. In a population-based prospective study (QSkin, n=38,854), we assessed melanoma risks associated with pigmentation characteristics and other phenotypes, and explored additive interactions. Read More

View Article
October 2018
5 Reads

Sublethal UV irradiation induces squamous differentiation via a p53-independent, DNA damage-mitosis checkpoint.

Cell Death Dis 2018 Oct 25;9(11):1094. Epub 2018 Oct 25.

Cell Cycle, Stem Cell Fate and Cancer Laboratory, Marqués de Valdecilla Research Institute (IDIVAL), 39011, Santander, Spain.

The epidermis is a self-renewal epithelium continuously exposed to the genotoxic effects of ultraviolet (UV) light, the main cause of skin cancer. Therefore, it needs robust self-protective mechanisms facing genomic damage. p53 has been shown to mediate apoptosis in sunburn cells of the epidermis. Read More

View Article
October 2018
3 Reads

Association between sunburn and demographic factors and health behaviour among Danish students.

Prev Med 2018 Oct 18;118:92-97. Epub 2018 Oct 18.

Danish SunSmart Campaign, Danish Cancer Society, Copenhagen, Denmark.

Sunburn is associated with an increased risk for skin cancer. Denmark has one of the highest incidences of melanoma in the world, although it is a relatively northern country. The objective of this study was to determine whether sunburn is associated with demographic factors and health behaviour among young Danes. Read More

View Article
October 2018
8 Reads

Host characteristics and risk of incident melanoma by Breslow thickness.

Cancer Epidemiol Biomarkers Prev 2018 Oct 19. Epub 2018 Oct 19.

Department of Dermatology, Brown University.

Background Several host characteristics, including pigmentary traits (hair color, sunburn susceptibility and tanning ability), number of common nevi (moles), and family history of melanoma, have been associated with risk of melanoma. Methods We prospectively examined the associations between host characteristics and risk of incident melanoma by Breslow thickness (≤1mm, thin melanoma; or >1mm, "thicker melanoma") based on the Nurses' Health Study (NHS, n=86,380 women), NHS-II (n=104,100 women), and Health Professionals Follow-up Study (HPFS, n=46,934 men). Results During 22~30 years' follow-up, a total of 1813 incident melanoma cases were identified with information on Breslow thickness, 1392 (76. Read More

View Article
October 2018
9 Reads

Development in sunburn 2007-2015 and skin cancer projections 2007-2040 of campaign results in the Danish population.

Medicine (Baltimore) 2018 Oct;97(41):e12738

Department of Prevention and Information, Danish Cancer Society, Strandboulevarden Copenhagen Ø, Denmark.

Exposure to ultraviolet radiation is the main risk factor for skin cancer. Denmark has one of the highest incidences of skin cancer in the world. In 2007, a long-term sun safety campaign was launched in Denmark. Read More

View Article
October 2018

Skin Cancer Preventive Behaviors in Iranian Farmers: Applying Protection Motivation Theory.

Workplace Health Saf 2018 Oct 10:2165079918796850. Epub 2018 Oct 10.

1 Hamadan University of Medical Sciences.

Farmers are among the most common work groups at risk of skin cancer. The protection motivation theory has been widely accepted as a framework for predicting health related behaviors. This study was conducted to determine the role of factors preventing skin cancer among farmers in Eslamabad-e Gharb district, Iran, using the protection motivation theory. Read More

View Article
October 2018

[Pathogenesis of systemic lupus erythematosus].

Z Rheumatol 2018 Nov;77(9):789-798

Klinik für Rheumatologie und Klinische Immunologie & Centrum für chronische Immundefizienz, Universitätsklinikum Freiburg und Medizinische Fakultät, Universität Freiburg, Hugstetterstr. 55, 79106, Freiburg, Deutschland.

The causes of diseases and disorders of the immune system, which lead to the development of systemic lupus erythematosus (SLE), are not yet completely understood; however, it is known that there are various mechanisms, which can lead to SLE. The development of the disease is based on an underlying genetic disposition but is first triggered by exposure to environmental factors, such as sunburn, viral infections or vitamin D deficiency. Disease flares can also be triggered by environmental factors. Read More

View Article
November 2018
2 Reads

Skin cancer risk perception and sun protection behavior at work, at leisure, and on sun holidays: a survey for Danish outdoor and indoor workers.

Environ Health Prev Med 2018 Oct 2;23(1):47. Epub 2018 Oct 2.

The Department of Occupational Medicine, Copenhagen University Holbaek, Gl. Ringstedvej 4B, 4300, Holbaek, Denmark.

Background: To prevent occupational skin cancer, it is essential that the sun-protective behavior of outdoor workers is adequate. The aim is to study the sun-protective behavior of Danish outdoor workers at work, at leisure, and on sun holiday and compare it to that of indoor workers.

Methods: This is a cross-sectional study, based on a 53-item survey completed by Danish outdoor (n = 380) and indoor workers (n = 119) in 2016-2017. Read More

View Article
October 2018
10 Reads

Cosmeceutical potential of geranium and calendula essential oil: Determination of antioxidant activity and in vitro sun protection factor.

J Cosmet Dermatol 2018 Sep 24. Epub 2018 Sep 24.

Faculty of Pharmacy, IFTM University, Moradabad, India.

The present investigation was aimed to find out the sun protection factor (SPF) and antioxidant potential of geranium essential oil (GEO) and calendula essential oil (CEO) because having a combination of these two properties moves up the oils as an active ingredient of various cosmeceutical formulations for their preventive and protective properties. Essential oils were obtained by hydrodistillation of Pelargonium graveolens leaves (GEO) and Calendula officinalis flowers (CEO). The composition and identification of chemical constituents of oils were determined by GCMS analysis. Read More

View Article
September 2018
1 Read
1.000 Impact Factor

Sparfloxacin-induced photo-onycholysis and photosensitivity characteristically sparing lepromatous skin lesions: an interesting observation.

Acta Dermatovenerol Alp Pannonica Adriat 2018 Sep;27(3):149-151

Gauhati Medical College and Hospital, Guwahati, Assam, India.

Sparfloxacin is an antibiotic in the quinolone group of antibacterial agents, which often induce photosensitive skin reactions, more often phototoxic reactions than photoallergic ones, and sometimes associated photo-onycholysis. We present a case of phototoxic dermatitis with photo-onycholysis in a 38-year-old man probably induced by sparfloxacin, which was prescribed to him along with rifampicin and clofazimine because he was suffering from borderline lepromatous leprosy. He developed exaggerated sunburn-like eruptions mainly on sun-exposed sites along with painful onycholysis of the fingernails. Read More

View Article
September 2018
3 Reads

Once-Daily Oral Sarecycline 1.5 mg/kg/day Is Effective for Moderate to Severe Acne Vulgaris: Results from Two Identically Designed, Phase 3, Randomized, Double-Blind Clinical Trials.

J Drugs Dermatol 2018 Sep;17(9):987-996

Background: Side effects may limit the use of current tetracycline-class antibiotics for acne.

Objective: Evaluate the efficacy and safety of once-daily sarecycline, a novel, narrow-spectrum tetracycline-class antibiotic, in moderate to severe acne.

Methods: Patients 9-45 years with moderate to severe facial acne (Investigator's Global Assessment [IGA] score ≥ 3, 20-50 inflammatory and ≤ 100 noninflammatory lesions, and ≤ 2 nodules) were randomized 1:1 to sarecycline 1. Read More

View Article
September 2018
19 Reads

Assessing the Potential Role for Topical Melatonin in an Antiaging Skin Regimen.

J Drugs Dermatol 2018 Sep;17(9):966-969

Background: Melatonin is an endogenous hormone commonly associated with regulation of sleep. However, over the last two decades, research has elucidated a range of effects associated with the compound, including anti-inflammatory, both direct and indirect antioxidant activity, tissue regenerative benefits, and preservation of mitochondrial function. Melatonin's anti-inflammatory and antioxidant support, coupled with its mitochondrial support, make it an intriguing target for use to support skin health. Read More

View Article
September 2018
15 Reads

Sun exposure among teenage and young adult cancer survivors in the United Kingdom.

Pediatr Blood Cancer 2019 Jan 13;66(1):e27424. Epub 2018 Sep 13.

Department of Behavioural Science and Health, University College London, London, United Kingdom.

Skin cancers are a common form of second malignant neoplasm among teenage and young adult cancer survivors (TYACS). The Children's Oncology Group specifies that TYACS should adhere to safe sun practices and be screened for skin cancer annually. Cross-sectional self-report data collected by our group indicate over a third of TYACS (n = 229; mean age: 19. Read More

View Article
January 2019

Clinical and Biological Characterization of Skin Pigmentation Diversity and Its Consequences on UV Impact.

Int J Mol Sci 2018 Sep 8;19(9). Epub 2018 Sep 8.

L'Oréal Research and Innovation, 1 avenue Eugène Schueller, 93601 Aulnay-sous-Bois, France.

Skin color diversity is the most variable and noticeable phenotypic trait in humans resulting from constitutive pigmentation variability. This paper will review the characterization of skin pigmentation diversity with a focus on the most recent data on the genetic basis of skin pigmentation, and the various methodologies for skin color assessment. Then, melanocyte activity and amount, type and distribution of melanins, which are the main drivers for skin pigmentation, are described. Read More

View Article
September 2018
1 Read

An international comparison of Google searches for sunscreen, sunburn, skin cancer, and melanoma: Current trends and public health implications.

Photodermatol Photoimmunol Photomed 2018 Sep 10. Epub 2018 Sep 10.

Departments of Dermatology and Population Health Sciences, University of Utah, Salt Lake City, Utah.

Background: Google Trends (GT) offers insight into public interests and behaviors and holds potential for guiding public health campaigns.

Objectives: This study explored international trends in English-speaking countries (United States, United Kingdom, Canada, Australia, New Zealand) in searches for sunscreen, sunburn, skin cancer, and melanoma to better guide skin cancer prevention campaigns.

Methods: Google Trends was queried for search terms from January 1, 2004 to December 31, 2017. Read More

View Article
September 2018
6 Reads

Sun behaviour and physical activity associated with autumn vitamin D status in 4-8-year-old Danish children.

Public Health Nutr 2018 Dec 7;21(17):3158-3167. Epub 2018 Sep 7.

1Department of Nutrition, Exercise and Sports, Faculty of Science,University of Copenhagen,Rolighedsvej 26,1958 Frederiksberg C,Denmark.

Objective: To explore determinants of serum 25-hydroxyvitamin D (s-25(OH)D) during autumn in young, Caucasian children not consuming vitamin D-fortified foods or supplements, and explore differences in sun behaviours between pre-school and school children.

Design: In September-October, s-25(OH)D was measured by LC-MS/MS; physical activity, sun behaviours and vitamin D intake were assessed with questionnaires.

Setting: Baseline data from the ODIN Junior trial at 55°N. Read More

View Article
December 2018

Filtered sunlight versus intensive electric powered phototherapy in moderate-to-severe neonatal hyperbilirubinaemia: a randomised controlled non-inferiority trial.

Lancet Glob Health 2018 Oct 28;6(10):e1122-e1131. Epub 2018 Aug 28.

Bowen University Teaching Hospital, Ogbomosho, Oyo, Nigeria.

Background: Kernicterus resulting from severe neonatal hyperbilirubinaemia is a leading cause of preventable deaths and disabilities in low-income and middle-income countries, partly because high-quality intensive phototherapy is unavailable. Previously, we showed that filtered-sunlight phototherapy (FSPT) was efficacious and safe for treatment of mild-to-moderate neonatal hyperbilirubinaemia. We aimed to extend these studies to infants with moderate-to-severe hyperbilirubinaemia. Read More

View Article
October 2018
2 Reads

Management of dental trauma in a child with Xeroderma Pigmentosa.

Saudi Dent J 2018 Jan 23;30(1):102-104. Epub 2017 Sep 23.

Department of Pedodontics and Preventive Dentistry, Institute of Dental Studies and Technologies, Kadrabad, Modinagar, Ghaziabad 201201, India.

Xeroderma Pigmentosa is a rare dermatological autosomal recessive disorder that manifests itself early in life as severe sunburn usually after a short exposure to sunlight. The prime characteristic features include photosensitivity, hyperpigmentation and ichthyosis in sun exposed areas, and an increase in the risk of basocellular and squamous cell carcinomas and melanomas of the skin and eyes. The case report highlights the preventive treatment options along with all necessary precautions that should be taken to protect the patient from any iatrogenic inadvertent exposures that may be deleterious to his present state. Read More

View Article
January 2018
2 Reads

Skin Self-examination for Skin Cancer Prevention-Reply.

JAMA 2018 08;320(7):721-722

Veterans Affairs Palo Alto Health Care System, Palo Alto, California.

View Article
August 2018
4 Reads

Skin Self-examination for Skin Cancer Prevention.

JAMA 2018 08;320(7):720-721

Department of Dermatology, New York University School of Medicine, New York, New York.

View Article
August 2018
6 Reads

Topical emulsion containing pyrrolidine dithiocarbamate: effectiveness against ultraviolet B irradiation-induced injury of hairless mouse skin.

J Pharm Pharmacol 2018 Nov 22;70(11):1461-1473. Epub 2018 Aug 22.

Department of Pharmaceutical Science, Health Science Center, State University of Londrina, Londrina, Brazil.

Objectives: To evaluate the effects of a topical emulsion containing pyrrolidine dithiocarbamate (PDTC) (EcPDTC) in skin oxidative stress and inflammation triggered by ultraviolet B (UVB) irradiation (dose of 4.14 J/cm ).

Methods: Hairless mouse received treatment with 0. Read More

View Article
November 2018
2 Reads

Effect of preharvest fruit bagging on fruit quality characteristics and incidence of fruit physiopathies in fully irrigated and water stressed pomegranate trees.

J Sci Food Agric 2018 Aug 20. Epub 2018 Aug 20.

Departamento de Producción Vegetal y Microbiología, Grupo de Investigación de Producción Vegetal y Tecnología, Universidad Miguel Hernández de Elche, Ctra. de Beniel, km 3.2, E-03312 Orihuela, Alicante, Spain.

Background: This report studied the response of pomegranate fruit under full irrigation (FI) and water stress conditions to bagging with externally glossy, single-layer, cellulosic paper bags, open at the bottom, from the end of fruit thinning to harvest time.

Results: Bagging decreased fruit size and the maturity index, and increased antioxidant activity in FI conditions. Moreover, fruit bagging substantially reduced the incidence of peel sunburn in both irrigation conditions. Read More

View Article

Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature.

Cell Death Dis 2018 Aug 6;9(8):835. Epub 2018 Aug 6.

Research Unit for Photodermatology, Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria.

Exposure of skin to ultraviolet (UV) radiation induces DNA damage, inflammation, and immune suppression that ultimately lead to skin cancer. However, some of the pathways that regulate these events are poorly understood. We exposed mice to UVB to study its early effects in the absence of Cbl-b, a known suppressor of antitumor immune response in the skin. Read More

View Article

Level of Education and Knowledge of Skin Cancer Risk Factors in Patients Undergoing Maintenance Hemodialysis.

Transplant Proc 2018 Jul - Aug;50(6):1621-1624. Epub 2018 Mar 13.

Department of Hygiene and Epidemiology, Medical University of Gdansk, Gdansk, Poland.

Introduction: An increased risk of skin cancer is particularly important in patients undergoing maintenance hemodialysis (HD), who are potential transplant recipients. In transplant recipients who are exposed to immunosuppressive therapy, neoplastic skin disease my take a more aggressive course. Increased exposure to photoradiation, elderly age, a low skin phototype, sunburn during childhood, and a history of smoking are the main factors contributing to the development of skin neoplasms. Read More

View Article
October 2018

Characteristics and Skin Cancer Risk Behaviors of Adult Sunless Tanners in the United States.

JAMA Dermatol 2018 Sep;154(9):1066-1071

Department of Dermatology, University of Minnesota, Minneapolis.

Importance: Incidence rates of nonmelanoma and melanoma skin cancers are increasing rapidly in the United States likely because of increased UV light exposure. Sunless tanning is a safe alternative to achieve tanned skin that might help reduce skin cancer incidence by deterring risky behaviors. However, limited data exist on the characteristics and associated skin cancer risk behaviors of sunless tanners in the United States. Read More

View Article
September 2018
1 Read

Chronic irradiation with 222-nm UVC light induces neither DNA damage nor epidermal lesions in mouse skin, even at high doses.

PLoS One 2018 25;13(7):e0201259. Epub 2018 Jul 25.

Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

Surgical site infections (SSIs) represent an important clinical problem associated with increased levels of surgical morbidity and mortality. UVC irradiation during surgery has been considered to represent a possible strategy to prevent the development of SSI. 254-nm UVC induces marked levels of DNA damage by generating cyclobutyl pyrimidine dimers (CPD) in microorganisms. Read More

View Article

Sunscreen Use and Melanoma Risk Among Young Australian Adults.

JAMA Dermatol 2018 Sep;154(9):1001-1009

Cancer Epidemiology and Prevention Research, Sydney School of Public Health, The University of Sydney, Camperdown, New South Wales, Australia.

Importance: There are limited data among young adults on sunscreen use during childhood and adulthood and on the association of sunscreen use with melanoma risk.

Objective: To assess correlates of early-life sunscreen use and the association between sunscreen use and risk of cutaneous melanoma before age 40 years.

Design, Setting, And Participants: This population-based, case-control family study analyzed Australian Melanoma Family Study data for persons with questionnaire data on sunscreen use collected by interview from 2001 to 2005 across 3 states in Australia, representing two-thirds of the country's population. Read More

View Article
September 2018
1 Read

Occupational UV Exposure and Sun-Protective Behaviour in German Outdoor Workers: Results of a Nationwide Study.

J Occup Environ Med 2018 Nov;60(11):961-967

Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany (Dr Schneider, Dr Diehl, Schilling, Spengler, Dr Görig); Association of Dermatological Prevention (ADP), Hamburg, Germany (Dr Greinert); Centre of Dermatology, Elbe Clinics, Buxtehude, Germany (Dr Greinert).

Objective: The aim of the National Cancer Aid Monitoring (NCAM) was to investigate which occupational groups (1) show higher sun exposure time, (2) suffer from sunburn, and (3) use recommended protective measures.

Methods: In 2016, a total of 485 individuals were classified as outdoor workers in accordance with ISCO-08 and asked about exposure time, prevalence of sunburn, and personal sun-protective measures on a sunny summer day.

Results: Outdoor workers were exposed to ultraviolet (UV) radiation for a mean time of 23. Read More

View Article
November 2018

Wrinkles, brown spots, and cancer: Relationship between appearance- and health-based knowledge and sunscreen use.

J Cosmet Dermatol 2018 Jul 16. Epub 2018 Jul 16.

UT Southwestern Medical Center, Dallas, Texas.

Background: There is increasing understanding that sunscreen use is associated with reduced photoaging and that appearance-based messages are more effective than health-based messages in promoting daily sunscreen use. We hypothesized that persons with greater awareness of the effects of photoaging use sunscreen more consistently.

Methods: Cross-sectional survey of adults in Dallas, TX, assessing sunscreen-related knowledge, behavior, and information source. Read More

View Article
July 2018
1 Read

The beta-adrenergic receptor agonist, terbutaline, reduces UVB-induced mechanical sensitization in humans.

Eur J Pain 2019 Jan 6;23(1):72-80. Epub 2018 Aug 6.

Department of Anaesthesiology and Intensive Care Medicine, University Clinic of Cologne, Cologne, Germany.

Objectives: Previously, we found in cultures of primary neurons and in animals that sensitized primary neurons can be desensitized by treatment with e.g. beta-adrenergic receptor agonists. Read More

View Article
January 2019

Review of environmental effects of oxybenzone and other sunscreen active ingredients.

J Am Acad Dermatol 2018 Nov 14. Epub 2018 Nov 14.

Department of Dermatology, Henry Ford Hospital, Detroit, Michigan. Electronic address:

With increasing awareness regarding the risks of sunburn, photoaging, and skin cancer, the use of sunscreens has increased. Organic and inorganic filters are used in sunscreen products worldwide. Concerns have been raised regarding the environmental effects of commonly used organic ultraviolet (UV) filters, including oxybenzone (benzophenone-3), 4-methylbenzylidene camphor, octocrylene, and octinoxate (ethylhexyl methoxycinnamate). Read More

View Article
November 2018
19 Reads

Racial disparities in fifth-grade sun protection: Evidence from the Healthy Passages study.

Pediatr Dermatol 2018 Sep 2;35(5):588-596. Epub 2018 Jul 2.

Department of Dermatology, School of Medicine, Emory University, Atlanta, GA, USA.

Background/objectives: Despite rising skin cancer rates in children, multiple studies reveal inadequate youth sun-protective behavior (eg, sunscreen use). Using Healthy Passages data for fifth-graders, we set out to determine sunscreen adherence in these children and investigated factors related to sunscreen performance.

Methods: Survey data were collected from 5119 fifth-graders and their primary caregivers. Read More

View Article
September 2018
2 Reads

Decision Tree Model vs Traditional Measures to Identify Patterns of Sun-Protective Behaviors and Sun Sensitivity Associated With Sunburn.

JAMA Dermatol 2018 Aug;154(8):897-902

Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland.

Importance: Understanding patterns of sun-protective behaviors and their association with sunburn can provide important insight into measurement approaches and intervention targets.

Objective: To assess whether decision-based modeling can be used to identify patterns of sun-protective behaviors associated with the likelihood of sunburn and to compare the predictive value of this method with traditional (ie, composite score) measurement approaches.

Design, Setting, And Participants: This cross-sectional study used a nationally representative sample of 31 162 US adults from the 2015 National Health Interview Survey, consisting of household interviews conducted in person and completed by telephone when necessary. Read More

View Article