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    Oral intake of Boesenbergia pandurata extract improves skin hydration, gloss, and wrinkling: A randomized, double-blind, and placebo-controlled study.
    J Cosmet Dermatol 2017 Apr 18. Epub 2017 Apr 18.
    Department of Biotechnology, Yonsei University, Seoul, Korea.
    Background: Photoaging is a severe skin damage that occurs as a result of exposure to external elements, primarily ultraviolet (UV) irradiation. Chronically, UV-irradiated skin exhibits the signs of sunburn and hyperpigmentation with the destruction of connective tissues. Previously, Boesenbergia pandurata (B. Read More

    [Sun protection factor 50+ : Pro and contra].
    Hautarzt 2017 Apr 11. Epub 2017 Apr 11.
    Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, 80337, München, Deutschland.
    The use of sunscreens with sun protection factors beyond 50 is controversial. In order to avoid misleading the consumer, several countries have already decided not to declare SPF beyond 50 on sunscreen products. Arguments against high SPF include the following: the risk of imbalanced protection, which could increase the risk of damage caused by longer-wave ultraviolet radiation; imparting a false sense of safety, which could lead to the extension of sun exposure times; health risks from higher concentrations of filter substances; and the only marginally higher blockade provided by high SPF sunscreens. Read More

    [Light protection for xeroderma pigmentosum].
    Hautarzt 2017 Apr 11. Epub 2017 Apr 11.
    Universitätsklinik für Dermatologie, Franz-Josef-Strauß Allee 11, 93053, Regensburg, Deutschland.
    Xeroderma pigmentosum is a rare autosomal recessive disorder which is caused by germinal mutations responsible for the repair of ultraviolet (UV) radiation-induced DNA lesions. It is characterized by hypersensitivity to UV radiation, poikiloderma, ocular surface disease, and in some patients pronounced sunburn and neurological disease. Patients have a very high risk of developing ocular and skin cancer on exposed body sites. Read More

    Kite-surfers' sun risk in the tropics.
    J Travel Med 2017 Mar;24(2)
    Department of Dermatology, CHU de Martinique (CHUM), Martinique, French West Indies.
    A preliminary inquiry, conducted on Martinique Island, sought to determine kite-surfers' sun-protection knowledge and behaviours. Results revealed good levels of knowledge and behaviours, but very frequent sunburns (74% had at least one sunburn during the last 6 months), with particularly severe sunburns exclusively among vacationers. These results argue for the double need to focus sunburn-prevention programs on vacationers and technically adapt sun-protection means to a tropical maritime environment. Read More

    Lifestyle and physiological factors associated with facial wrinkling in men and women.
    J Invest Dermatol 2017 Apr 6. Epub 2017 Apr 6.
    Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands. Electronic address:
    Facial wrinkling is one of the most notable signs of skin aging. Men and women show different wrinkling patterns yet the lifestyle and physiological factors underlying these sex-specific patterns are relatively unknown. Here, we investigated sex-specific determinants for facial wrinkles. Read More

    Data on solar sunburning ultraviolet (UVB) radiation at an urban Mediterranean climate.
    Data Brief 2017 Apr 11;11:597-600. Epub 2017 Mar 11.
    Medical School, University of Cyprus, Nicosia, Cyprus.
    This article describes data on the intensity of ultraviolet B (UVB) radiation collected during field questionnaire-based surveys in Athens, Greece. The surveys were conducted over 11 days of July and October 2010 at three different urban, outdoor sites. A total of 1104 interviews were conducted. Read More

    The impact of oral Polypodium leucotomos extract on ultraviolet B response: A human clinical study.
    J Am Acad Dermatol 2017 Mar 21. Epub 2017 Mar 21.
    Multicultural Dermatology Center, Department of Dermatology, Henry Ford Hospital, Detroit, Michigan. Electronic address:
    Background: There is a rationale for adding systemic photoprotective agents to the current photoprotection regimen.

    Objective: This study was designed to objectively evaluate the molecular and photobiologic effects of oral administration of Polypodium leucotomos extract (PLE).

    Methods: In all, 22 subjects with Fitzpatrick skin phototype I to III were enrolled. Read More

    Skin cancer history, sun-related attitudes, behaviour and sunburn among renal transplant recipients versus general population.
    Australas J Dermatol 2017 Mar 23. Epub 2017 Mar 23.
    Department of Medicine (Dermatology), St Vincent's Hospital, Melbourne, Victoria, Australia.
    Background/objectives: Renal transplant recipients (RTR) have both an excessive skin cancer incidence and a high mortality rate. In Australia RTR receive extensive public education on skin cancer and many undergo further education pre/post-transplant. This study examines whether RTR have sufficiently rigorous sun protection behaviour compared with the general population. Read More

    Research on Skin Cancer-Related Behaviors and Outcomes in the NIH Grant Portfolio, 2000-2014: Skin Cancer Intervention Across the Cancer Control Continuum (SCI-3C).
    JAMA Dermatol 2017 Mar 22. Epub 2017 Mar 22.
    Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
    Importance: The Surgeon General's Call to Action to Prevent Skin Cancer broadly identified research gaps, but specific objectives are needed to further behavioral intervention research.

    Objective: To review National Institute of Health (NIH) grants targeting skin cancer-related behaviors and relevant outcomes.

    Design, Setting, And Participants: A portfolio analysis of the title, abstract, specific aims, and research plans of identified grant applications from 2000 to 2014 targeting skin cancer-related behaviors or testing behavioral intervention effects on cancer-relevant outcomes along the cancer continuum. Read More

    Pigmentation phenotype, photosensitivity and skin neoplasms in patients with myotonic dystrophy.
    Eur J Neurol 2017 May 20;24(5):713-718. Epub 2017 Mar 20.
    Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA.
    Background And Purpose: Recent studies have suggested a possible excess risk of skin neoplasms in patients with myotonic dystrophy (DM). Risk factors related to this observation have not been defined.

    Method: Information regarding personal history of skin tumors, pigmentation phenotype, and skin reaction to sun exposure were collected from 266 DM patients who were enrolled in the US National Institutes of Health National Registry of Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Patients and Family Members. Read More

    Phototoxicity of Doxycycline: A Systematic Review on Clinical Manifestations, Frequency, Cofactors, and Prevention.
    Skin Pharmacol Physiol 2017 Mar 15;30(2):76-80. Epub 2017 Mar 15.
    Department of Dermatology, University Hospital Jena, Jena, Germany.
    Background: One of the most important dermatologic side effects of doxycycline is photosensitivity. As doxycycline is important for malaria prophylaxis and malaria is mainly spread in countries with high sun radiation, special attention should be paid to this adverse effect. While there are many publications on the phototoxicity of tetracyclines in general, only a few exist focusing on doxycycline. Read More

    Knowledge and attitudes of UK university students in relation to ultraviolet radiation (UVR) exposure and their sun-related behaviours: a qualitative study.
    BMJ Open 2017 Mar 13;7(3):e014388. Epub 2017 Mar 13.
    Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
    Objectives: To explore whether knowledge about the harms of ultraviolet radiation (UVR) influences UK university students' sun-related behaviours and examine in depth their attitudes towards: sun protection, natural and artificial tanning behaviours.

    Design: Qualitative methodology with 15 semistructured, individual interviews. Thematic analysis using the Framework Method with analyst triangulation and member validation. Read More

    In vitro skin models for the evaluation of sunscreen-based skin photoprotection: molecular methodologies and opportunities.
    Curr Med Chem 2017 Mar 3. Epub 2017 Mar 3.
    L`Oreal Research and Innovation, 1 avenue Eugène Schueller , Aulnay sous Bois 93600. France.
    Identifying and understanding the biological events that occur following ultraviolet (UV) exposure are mandatory to elucidate the biological and clinical consequences of sun exposure, and to provide efficient and adequate photoprotection strategies. The main UV-induced biological features (markers related to sunburn, cancer, photoaging immunosuppression, pigmentation), characterized in human skin in vivo, could be reproduced in adapted models of reconstructed skin in vitro, attesting their high relevance in the field of photobiology. In turn, 3D skin models were useful to discover precise biological pathways involved in UV response and were predictive of in vivo situation. Read More

    Prevalence of Indoor Tanning and Association With Sunburn Among Youth in the United States.
    JAMA Dermatol 2017 Mar 3. Epub 2017 Mar 3.
    Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
    Importance: Indoor tanning and sunburns, particularly during adolescence and young adulthood, increase the risk of developing skin cancer.

    Objective: To examine the trends in the prevalence of indoor tanning and the association between indoor tanning and sunburn among US high school students.

    Design, Setting, And Participants: This study pooled and examined cross-sectional data from the 2009, 2011, 2013, and 2015 national Youth Risk Behavior Survey. Read More

    Attitudes and Behaviors Related to Sun-Safety in College Students.
    J Community Health 2017 Feb 27. Epub 2017 Feb 27.
    Department of Public Health, William Paterson University, University Hall 366, Wayne, NJ, 07470, USA.
    The purpose of this study was to determine the level of sun safe behaviors, as well as to measure knowledge and attitudes toward being tan in a sample of college students. The sample was comprised of 315 college students attending a personal health course. During Fall of 2016, a survey was distributed to assess knowledge, attitudes, and behaviors of university students regarding skin cancer related behaviors. Read More

    Predictors of Sunburn Risk Among Florida Residents.
    J Am Osteopath Assoc 2017 Mar;117(3):150-157
    Context: The incidence of skin cancer, the most common type of cancer in the United States, is increasing. Sunburn is a major modifiable risk factor for skin cancer, and its prevalence among the US population is high.

    Objectives: To identify predictors of having had a red or painful sunburn in the past 12 months among people living in Florida. Read More

    Development of Photoonycholysis with Vandetanib Therapy.
    Skin Appendage Disord 2017 Jan 3;2(3-4):146-151. Epub 2016 Nov 3.
    Department of Oncodermatology, Institut Claudius Regaud, Institut Universitaire du Cancer, Toulouse Oncopole, Toulouse, France; Department of Medical Oncology and Clinical Research, Institut Claudius Regaud, Institut Universitaire du Cancer, Toulouse Oncopole, Toulouse, France.
    Vandetanib therapy is a novel once-daily oral multitargeted tyrosine kinase inhibitor, which is currently used in advanced or metastatic medullary thyroid cancer. Skin toxicities are among the most prevalent adverse events reported with this targeted therapy (e.g. Read More

    Marine and Other Aquatic Dermatoses.
    Indian J Dermatol 2017 Jan-Feb;62(1):66-78
    Diving School, Naval Base, Kochi, Kerala, India.
    Occupational and recreational aquatic activity predisposes our population to a wide variety of dermatoses. Sunburn, urticaria, jellyfish stings, and contact dermatitis to rubber equipment are common allergies that are encountered in the aquatic environment. Among the infections, tinea versicolor, intertrigo, and verruca vulgaris are widespread. Read More

    High Altitude Dermatology.
    Indian J Dermatol 2017 Jan-Feb;62(1):59-65
    Department of Dermatology, Military Hospital, Ahmedabad, Gujarat, India.
    Approximately, 140 million people worldwide live permanently at high altitudes (HAs) and approximately another 40 million people travel to HA area (HAA) every year for reasons of occupation, sports or recreation. In India, whole of Ladakh region, part of Northwest Kashmir, Northern part of Sikkim and Tenga valley of Arunachal are considered inhabited areas of HAA. The low quantity of oxygen, high exposure of ultraviolet (UV) light, very low humidity, extreme subzero temperature in winter, high wind velocity, make this region difficult for lowlanders as well as for tourists. Read More

    Pigmentation Traits, Sun Exposure, and Risk of Incident Vitiligo in Women.
    J Invest Dermatol 2017 Feb 14. Epub 2017 Feb 14.
    Department of Dermatology, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA; Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
    Vitiligo is the most common cutaneous depigmentation disorder worldwide, yet little is known about specific risk factors for disease development. Using data from the Nurses' Health Study, a prospective cohort study of 51,337 white women, we examined the associations between (i) pigmentary traits and (ii) reactions to sun exposure and risk of incident vitiligo. Nurses' Health Study participants responded to a question about clinician-diagnosed vitiligo and year of diagnosis (2001 or before, 2002-2005, 2006-2009, 2010-2011, or 2012+). Read More

    Protective Role of Mitochondrial Peroxiredoxin III against UVB-Induced Apoptosis of Epidermal Keratinocytes.
    J Invest Dermatol 2017 Feb 12. Epub 2017 Feb 12.
    Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea; College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea. Electronic address:
    UVB light induces generation of reactive oxygen species, ultimately leading to skin cell damage. Mitochondria are a major source of reactive oxygen species in UVB-irradiated skin cells, with increased levels of mitochondrial reactive oxygen species having been implicated in keratinocyte apoptosis. Peroxiredoxin III (PrxIII) is the most abundant and potent H2O2-removing enzyme in the mitochondria of most cell types. Read More

    Travelling abroad with cystic fibrosis: Assessment of risks and healthcare requirements.
    Respir Med 2017 Apr 24;125:92-93. Epub 2017 Jan 24.
    Adult Cystic Fibrosis Centre, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK. Electronic address:
    There is limited information on the risks and healthcare requirements of patients with cystic fibrosis (CF) undertaking travel abroad. Of 100 patients (mean age 24.7 years, mean FEV1 57. Read More

    Protective effects of Polypodium leucotomos extract against UVB-induced damage in a model of reconstructed human epidermis.
    Photodermatol Photoimmunol Photomed 2017 Jan 31. Epub 2017 Jan 31.
    Medical Direction Difa Cooper, Caronno Pertusella, Italy.
    Background: Polypodium leucotomos (PL) exerts potent antioxidant, photo-protective, and immune-modulatory activities. A reconstructed human epidermis (RHE) (Episkin) is a suitable model for the evaluation of acute UV-induced cell damage. No data regarding the photo-protective action of PL in this model are available. Read More

    Vitamin D status and risk for malignant cutaneous melanoma: recent advances.
    Eur J Cancer Prev 2017 Jan 25. Epub 2017 Jan 25.
    aInstitute of Food Sciences, National Research Council (CNR), Avellino bDepartment of Surgical, Microsurgical and Medical Sciences, University of Sassari cInstitute of Biomolecular Chemistry, National Research Council (CNR), Cancer Genetics Unit, Sassari dRomagna Scientific Institute for the Study and Cure of Tumors, Skin Cancer Unit, Meldola, Italy.
    Cutaneous malignant melanoma, whose incidence is increasing steadily worldwide, is the result of complex interactions between individual genetic factors and environmental risk factors. Ultraviolet radiation represents the most important environmental risk factor for the development of skin cancers, including melanoma. Sun exposure and early sunburn during childhood are the principal causes of cutaneous melanoma insurgence in adults, with double the risk relative to a nonexposed population. Read More

    Sun Protection by Beach Umbrella vs Sunscreen With a High Sun Protection Factor: A Randomized Clinical Trial.
    JAMA Dermatol 2017 Mar;153(3):304-308
    Department of Dermatology, New York University School of Medicine, New York.
    Importance: Sun-protective behavior affects skin cancer prevention. Shade works by physically shielding skin from direct harmful UV rays; however, skin may still remain exposed to reflected and indirect UV rays. There is no current standard metric to evaluate shade for its effectiveness in sun protection, and there is insufficient clinical evidence that a beach umbrella alone can provide adequate sun protection. Read More

    Tanning equipment use: 2014 Canadian Community Health Survey.
    Health Rep 2017 Jan;28(1):12-16
    Environmental Health Science and Research Bureau, Population Studies Division, Health Canada, Ottawa, Ontario.
    Background: Tanning equipment use is related to the early onset of cancer, with the risk increasing as the duration and repetition of exposure increase. In 2009, the International Agency for Research on Cancer classified tanning equipment use as carcinogenic to humans, and according to the World Health Organization, the risk of skin melanoma increases significantly when use begins before age 35.

    Data And Methods: The rapid response component of the 2014 Canadian Community Health Survey collected data on the use of tanning equipment in the previous 12 months, including reasons for use, frequency/duration of use, precautions taken, and adverse reactions or injuries. Read More

    Detailed Audiological Evaluation of a Patient with Xeroderma Pigmentosum with Neural Degeneration.
    J Am Acad Audiol 2017 Jan;28(1):80-90
    Department of Genetics, Louisiana State University Health Sciences Center, New Orleans, LA.
    Background: Xeroderma pigmentosum (XP) is a rare autosomal recessive condition characterized by extreme sensitivity to ultraviolet light. Individuals with XP lack the ability to repair DNA (deoxyribonucleic acid) damage caused by ultraviolet radiation, leading to sunburn and increased susceptibility to skin cancers. Approximately 25% of patients also exhibit neural degeneration, which includes progressive mental deterioration, cortical thinning, and sensorineural hearing loss. Read More

    Ultraviolet radiation and the skin: Photobiology and sunscreen photoprotection.
    J Am Acad Dermatol 2017 Mar 27;76(3S1):S100-S109. Epub 2016 Dec 27.
    Clinical Skin Research and Development Center, Pierre Fabre Dermo-Cosmétique, Toulouse, France; Department of Dermatology, Toulouse University Hospital, Toulouse, France.
    The efficacy of sunscreens can be measured by different methods, involving in vitro, ex vivo, or in vivo techniques. There is a need for a worldwide standardization of these methods to avoid misunderstanding and confusion among sunscreen users. The clinical benefits of sunscreens have been demonstrated in randomized controlled trials that established the role of sunscreens in the prevention of actinic keratoses, squamous cell carcinomas, nevi, and melanomas. Read More

    Melanoma awareness and prevalence of dermoscopic examination among internet users: a cross-sectional survey.
    Postepy Dermatol Alergol 2016 Dec 2;33(6):421-428. Epub 2016 Dec 2.
    Department of Epidemiology, Maria Skłodowska-Curie Memorial Cancer Centre and Institute of Oncology Gliwice Branch, Gliwice, Poland.
    Introduction: Melanoma presents the greater threat to health the later the disease is detected and treated, although treatment results can be improved by the widespread use of dermoscopy. However, scarce data are available concerning the awareness of dermoscopy and the frequency of its performance in the non-patient population.

    Aim: To assess the awareness of melanoma detection by dermoscopic examination among the audience of a scientific website. Read More

    [Secrets of the red-headed].
    Pol Merkur Lekarski 2016 Dec;41(246):306-309
    Medical University of Wrocław Poland: Students of Medical Faculty.
    Only 1-2% of people is red-headed but in the Russian Udmurt Republic or United Kingdom they can be met more often. A specific variant of MC1R gene (R allele) is responsible for the red hair. The gene encodes a receptor for melanocortins. Read More

    Georgian Med News 2016 Nov(Issue):95-100
    National University of Pharmacy, Kharkiv; Kharkiv National Medical University; State institution "State Expert Center MoH Ukraine", Kiev, Ukraine.
    The purpose of this study was to assess the impact of ultraviolet irradiation (UV) on morphological and functional condition of the skin in guinea pigs. The study involved 30 albino guinea pigs weighing 400-500 g subjected to local exposure to UV irradiation. Control group consisted of intact guinea pigs. Read More

    Identifying people at higher risk of melanoma across the U.K.: a primary-care-based electronic survey.
    Br J Dermatol 2017 Apr 23;176(4):939-948. Epub 2016 Dec 23.
    Primary Care Unit, Department of Public Health & Primary Care, University of Cambridge School of Clinical Medicine, Strangeways Research Laboratory, Cambridge, CB1 8RN, U.K.
    Background: Melanoma incidence is rising rapidly worldwide among white populations. Defining higher-risk populations using risk prediction models may help targeted screening and early detection approaches.

    Objectives: To assess the feasibility of identifying people at higher risk of melanoma using the Williams self-assessed clinical risk estimation model in U. Read More

    Correlates of sun protection behaviors among Hispanic children residing in a high UVR environment.
    Photodermatol Photoimmunol Photomed 2017 Mar 17;33(2):75-83. Epub 2017 Jan 17.
    Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
    Background/purpose: Rates of melanoma are rising in Hispanics in the United States. Excessive sun exposure in childhood increases the risk of melanoma in adulthood, and little is known about the factors motivating sun protection behaviors among Hispanic youth.

    Methods: Correlates of sun protection were examined among Hispanic children residing in Los Angeles, California (N = 1891). Read More

    Expansion of the genotypic and phenotypic spectrum of xeroderma pigmentosum in Chinese population.
    Photodermatol Photoimmunol Photomed 2017 Jan;33(1):58-63
    Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
    Background: Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by exaggerated sunburn reactions, freckle-like pigmentation, and a high possibility of developing cutaneous tumors. XP comprised seven complementation groups (from XP-A to XP-G) and a variant form XP-V.

    Methods: This study was based on five unrelated Chinese families with six patients clinically suspected to be XP. Read More

    Factors associated with regular sunscreen use by medical students of a Peruvian university.
    J Prev Med Hyg 2016 Sep;57(3):E172-E177
    CRONICAS Center of Excellence for Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
    Introduction: Use of sunscreen is encouraged to reduce the risk of skin pathologies caused by radiation. It is important to acknowledge the associated factors that promote or hinder sunscreen use in young populations as to design better prevention policies.

    Objective: To determine the factors associated with regular sunscreen use among first year medical students from a Peruvian university. Read More

    Impact of Cluster Zone Leaf Removal on Grapes cv. Regent Polyphenol Content by the UPLC-PDA/MS Method.
    Molecules 2016 Dec 11;21(12). Epub 2016 Dec 11.
    Department of Fruit and Vegetable Processing, Wroclaw University of Environmental and Life Sciences, Chełmońskiego 37 Street, 51-630 Wrocław, Poland.
    Leaf removal is known to enhance light exposure of clusters and therefore may affect grape composition. Owing to the risk of decreasing grape quality or sunburn as a consequence of improper sun exposure, it is crucial to determine the optimum leaf removal techniques adequate for the particular climate conditions of a vineyard area. Defoliation experiments on vine cv. Read More

    The risks and benefits of sun exposure 2016.
    Dermatoendocrinol 2016 Jan-Dec;8(1):e1248325. Epub 2016 Oct 19.
    Section of Endocrinology, Diabetes and Nutrition, Department of Medicine, Boston University Medical Center , Boston, MA, USA.
    Public health authorities in the United States are recommending that men, women and children reduce their exposure to sunlight, based on concerns that this exposure will promote skin cancer. On the other hand, data show that increasing numbers of Americans suffer from vitamin D deficiencies and serious health problems caused by insufficient sun exposure. The body of science concerning the benefits of moderate sun exposure is growing rapidly, and is causing a different perception of sun/UV as it relates to human health. Read More

    Translation and adaptation of skin cancer genomic risk education materials for implementation in primary care.
    J Community Genet 2017 Jan 6;8(1):53-63. Epub 2016 Dec 6.
    Memorial Sloan Kettering Cancer Center, 641 Lexington Ave. 7th Floor, New York, NY, 10022, USA.
    Genomic medicine has revolutionized disease risk identification and subsequent risk reduction interventions. Skin cancer risk genomic feedback is a promising vehicle to raise awareness and protective behaviors in the general population, including Hispanics who are largely unaware of their risks. Yet, personalized genomics currently has limited reach. Read More

    Number and size of acquired melanocytic nevi and affecting risk factors in cases admitted to the dermatology clinic.
    Postepy Dermatol Alergol 2016 Oct 21;33(5):375-380. Epub 2016 Oct 21.
    Dermatology Clinic, School of Medicine, Balıkesir University, Balıkesir, Turkey.
    Introduction: The size and number of acquired melanocytic nevi (AMN) and presence of dysplastic nevi are the leading risk factors that should be recognized in the development of malignant melanoma.

    Aim: To evaluate AMN and risk factors in the development of AMN in all age groups admitted to a dermatology outpatient clinic.

    Material And Methods: Four hundred and twelve patients who were admitted to the dermatology outpatient clinic for any dermatological symptom and who accepted to participate in the study were randomly included in the study. Read More

    Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors.
    Oncotarget 2016 Dec;7(52):86740-86754
    Department of Dermatology, LUMC, Leiden, The Netherlands.
    Lgr6+ cells have been identified as a novel class of proliferating (Ki67+) stem cells in mouse epidermis. We investigated their response to UV exposure in Lgr6-EGFP-Ires-CreERT2/R26R-LacZ haired and hairless mice and whether they become initiating cells of UV- or chemically induced skin tumors. UV overexposure erased Lgr6+ cells (EGFP+) from the interfollicular epidermis (IFE), but - as after wounding - they apparently repopulated the IFE from the hair follicles. Read More

    Sun protective behaviour and sunburn prevalence in primary and secondary schoolchildren in western Switzerland.
    Swiss Med Wkly 2016 12;146:w14370. Epub 2016 Nov 12.
    Division of Chronic Diseases, Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Switzerland.
    Aims Of The Study: Although solar overexposure during childhood and adolescence increases the risk of melanoma, determinants of sunburn and sun protective behaviours of Swiss children have scarcely been explored. We investigated sunburn occurrence and sun protective behaviours of schoolchildren in western Switzerland, the region with the highest incidence of melanoma in Europe.

    Material And Methods: Self-reported questionnaires were administered during regular classes to pupils in 5th (primary school, n = 431), 8th and 11th grades (secondary school, n = 837) in the 18 public schools of La Chaux-de-Fonds. Read More

    Nanoencapsulation of coenzyme Q10 and vitamin E acetate protects against UVB radiation-induced skin injury in mice.
    Colloids Surf B Biointerfaces 2017 Feb 9;150:32-40. Epub 2016 Nov 9.
    Programa de Pós-Graduação em Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Santa Maria 97105-900, Brazil; Departamento de Farmácia Industrial, Universidade Federal de Santa Maria, Santa Maria 97105-900, Brazil. Electronic address:
    This study aimed to investigate the feasibility of producing semisolid formulations based on nanocapsule suspensions containing the association of the coenzyme Q10 and vitamin E acetate by adding gellan gum (2%) to the suspensions. Furthermore, we studied their application as an alternative for the treatment of inflammation induced by ultraviolet B (UVB) radiation. For this, an animal model of injury induced by UVB-radiation was employed. Read More

    Irradiance-dependent UVB Photocarcinogenesis.
    Sci Rep 2016 Nov 21;6:37403. Epub 2016 Nov 21.
    Department of Dermatology, Kaohsiung Medical University Hospital, Department of Dermatology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
    Ultraviolet B (UVB) radiation from the sun may lead to photocarcinogenesis of the skin. Sunscreens were used to protect the skin by reducing UVB irradiance, but sunscreen use did not reduce sunburn episodes. It was shown that UVB-induced erythema depends on surface exposure but not irradiance of UVB. Read More

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