4,073 results match your criteria Sunburn


Phloroglucinol Attenuates Ultraviolet B-Induced 8-Oxoguanine Formation in Human HaCaT Keratinocytes through Akt and ErkMediated Nrf2/Ogg1 Signaling Pathways.

Biomol Ther (Seoul) 2020 Jun 26. Epub 2020 Jun 26.

Department of Biochemistry, College of Medicine, Jeju National University and Jeju Research Center for Natural Medicine, Jeju 63243, Republic of Korea.

Ultraviolet B (UVB) radiation causes DNA base modifications. One of these changes leads to the generation of 8-oxoguanine (8- oxoG) due to oxidative stress. In human skin, this modification may induce sunburn, inflammation, and aging and may ultimately result in cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4062/biomolther.2020.059DOI Listing

Aspirin protects melanocytes and keratinocytes against UVB-induced DNA damage in vivo.

J Invest Dermatol 2020 Jun 19. Epub 2020 Jun 19.

Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah; Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah; Department of Oncological Sciences, University of Utah, Salt Lake City, Utah. Electronic address:

Ultraviolet (UV) radiation promotes skin cancer through multiple mechanisms, including induction of inflammation, oxidative stress, and DNA damage such as 8-oxoguanine (8-OG) and cyclobutane pyrimidine dimers (CPD). We investigated whether the anti-inflammatory activities of aspirin (ASA) could protect against UVB-induced DNA damage and skin carcinogenesis. ASA reduced UVB-induced 8-OG and CPD in Melan-a melanocytes and HaCat keratinocytes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2020.06.003DOI Listing

Trifarotene for the Treatment of Facial and Truncal Acne.

Ann Pharmacother 2020 Jun 21:1060028020934892. Epub 2020 Jun 21.

MedStar Washington Hospital Center and MedStar Georgetown University Hospital, Washington, DC, USA.

This article reviews clinical trials to assess the efficacy, safety, and clinical application of trifarotene 0.005% cream (Aklief). A systematic review of the literature was performed using the terms OR OR in MEDLINE (PubMed) and EMBASE databases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1060028020934892DOI Listing

Potential of Skin Microbiome, Pro- and/or Pre-Biotics to Affect Local Cutaneous Responses to UV Exposure.

Nutrients 2020 Jun 17;12(6). Epub 2020 Jun 17.

Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, 8010 Graz, Austria.

The human skin hosts innumerable microorganisms and maintains homeostasis with the local immune system despite the challenges offered by environmental factors such as ultraviolet radiation (UVR). UVR causes cutaneous alterations such as acute (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu12061795DOI Listing

Vemurafenib-related photosensitivity.

J Dtsch Dermatol Ges 2020 Jun 18. Epub 2020 Jun 18.

Department of Dermatology and Allergology, Biederstein, School of Medicine, Technical University, Munich, Germany.

Increased photosensitivity is a common cutaneous adverse effect associated with the BRAF inhibitor vemurafenib. Clinically, it presents as an immediate sensation of heat and edematous erythema during sun exposure, as well as a sunburn reaction in terms of a late reaction. Phototesting has shown that the UVA range (320 nm to 400 nm), for both the immediate and the late reaction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ddg.14140DOI Listing

Concerns about vitamin D and sun exposure behaviour among Australians.

Health Promot J Austr 2020 Jun 18. Epub 2020 Jun 18.

Centre for Behavioural Research in Cancer, Cancer Council Victoria, Melbourne, Victoria, Australia.

Issues addressed Australians' concerns about vitamin D and influence on sun protection were last quantified a decade ago in Queensland amidst media attention on emerging evidence of non-skeletal benefits of vitamin D. Meanwhile these circumstances persist, and impact is worth assessing.

Methods: Measures of concern about vitamin D were included in three recent population-based cross-sectional surveys of Australians' sun-related behaviours during summer months (2010-11, 2013-14 and 2016-17). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hpja.372DOI Listing

[Effects of solar radiation and an update on photoprotection].

An Pediatr (Barc) 2020 Jun 6;92(6):377.e1-377.e9. Epub 2020 Jun 6.

Unidad de Dermatología Pediátrica, Departamento de Dermatología, Hospital Universitario Reina Sofía, Córdoba, España.

Sunburn, immunodepression, photoaging, and photocarcinogenesis, are some of the most significant adverse effects of solar radiation in humans. Children are population group of special vulnerability, due to the fact that exposure to the sun has more pronounced biological effects compared to adults. Furthermore, childhood is a critical period for promoting the development of photo damage and photocarcinogenesis in the later stages of life if adequate measures at not put into place. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anpedi.2020.04.014DOI Listing

Toxic effects and transcriptome analyses of zebrafish (Danio rerio) larvae exposed to benzophenones.

Environ Pollut 2020 May 27;265(Pt A):114857. Epub 2020 May 27.

School of Life Sciences, The Chinese University of Hong Kong, Sha Tin, N.T., Hong Kong. Electronic address:

Sunscreen chemicals, such as benzophenones (BPs), are common environmental contaminants that are posing a growing health concern due to their increasing presence in water, fish, and human systems. Benzoresorcinol (BP1), oxybenzone (BP3), and dioxybenzone (BP8) are the most commonly used BPs for their ability to protect from sunburn by absorbing a broad spectrum of ultraviolet radiation. In this study, zebrafish larvae were used as an in vivo model to investigate the potential risks and molecular mechanisms of the toxic effects of BPs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.envpol.2020.114857DOI Listing

Numerical estimations of the daily amount of skin-synthesized vitamin D by pre-school children in Poland.

J Photochem Photobiol B 2020 Jul 16;208:111898. Epub 2020 May 16.

Institute of Geophysics, Polish Academy of Sciences, Warsaw, Poland.

According to Polish guidelines, children need a daily dose of 600-1000 I·U. vitamin D, which could be skin-synthesized in the period May to September, after at least 15 min solar exposure between 10 am and 3 pm with uncovered forearms and lower legs. In Poland, doctors only prescribe oral supplementation to infants and small children up to 2 years old, rarely for the older children. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jphotobiol.2020.111898DOI Listing

Prevalence and correlates of sun protections with sunburn and vitamin D deficiency in sun-sensitive individuals.

J Eur Acad Dermatol Venereol 2020 May 26. Epub 2020 May 26.

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Background: Sun sensitivity is an inherent risk factor for skin cancer. Sun protection is important in sun-sensitive individuals to reduce sunburns for skin cancer prevention. However, concerns have arose regarding the possible impact of sun protection on vitamin D deficiency. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jdv.16681DOI Listing

Impact of Sun Exposure and Tanning Patterns on Next-Generation Sequencing Mutations in Melanoma.

J Surg Res 2020 May 20;254:147-153. Epub 2020 May 20.

Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania. Electronic address:

Background: For the past 30 y, the incidence rate of malignant melanoma has risen steadily. Ultraviolet radiation exposure has been identified as the most prevalent modifiable risk factor for melanoma. Here, next-generation sequencing was used to analyze the relationship between multiple sun exposure factors and select cancer-related genes to determine the relationship of sun exposure on the molecular profiles of melanomas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jss.2020.04.021DOI Listing

Effectiveness of SolSano Program on Sun Protection Habits, Knowledge, and Attitudes Among University Students.

Actas Dermosifiliogr 2020 May 18. Epub 2020 May 18.

Servicio de Dermatología, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, España. Electronic address:

Background And Objective: The SolSano (HealthySun) project is a primary school sun education program that has been running in Aragon, Spain, since 2000. In the short term, it has proven to be effective at promoting sun protection behaviors and heightening awareness in childhood. The aim of this study was to evaluate the long-term effectiveness of the SolSano program. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ad.2019.08.002DOI Listing

Text message reminders for improving sun protection habits: A systematic review.

PLoS One 2020 19;15(5):e0233220. Epub 2020 May 19.

Universidad San Ignacio de Loyola, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Lima, Peru.

Background: Excessive exposure to ultraviolet radiation increases the risk of skin cancer and other conditions. SMS text reminders may be a useful tool to improve sun protection habits due to its massive reach, low cost, and accessibility.

Objective: To perform a systematic review of randomized controlled trials (RCTs) that evaluated the effects of SMS text reminders in promoting sun protection habits. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233220PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236986PMC

Validation of a Questionnaire Designed to Study Knowledge, Attitudes, and Habits Related to Sun Exposure Among Young Adults: The CHACES Questionnaire.

Actas Dermosifiliogr 2020 May 14. Epub 2020 May 14.

Servicio de Dermatología, Hospital Costa del Sol, Marbella, España.

Skin cancer prevention campaigns in schools have been shown to be both effective and cost-effective. The success of such programs depends on the use of an appropriate design informed by a prior survey of the target population (pupils, teachers, and parents). There are, however, very few validated Spanish-language questionnaires designed to study the habits and knowledge of this population with respect to sun exposure in childhood and none designed for use with a young adult population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ad.2020.02.002DOI Listing

Biomarkers in melanoma and non-melanoma skin cancer prevention and risk stratification.

Exp Dermatol 2020 May 16. Epub 2020 May 16.

The Hormel Institute, University of Minnesota, Austin, MN, USA.

The rates of melanoma and non-melanoma skin cancer (NMSC) have been increasing over the last twenty years in the United States, and this has been attributed to increased ultraviolet radiation exposure (UVR). Given these rising rates, preventative measures have become increasingly important to reduce the incidence and promote early detection of these cancers. Skin cancer prevention remains a challenging task to accomplish mainly due to the lack of reliable and sensitive methods to provide objective risk information that can educate and motivate individuals to avoid sunburn. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.14114DOI Listing

[Disease spectrum among guests and staff of an international luxury beach resort in the tropics].

Authors:
Andreas Fichtner

Med Klin Intensivmed Notfmed 2020 May 7. Epub 2020 May 7.

Notfall- und OP-Management, Kreiskrankenhaus Freiberg gGmbH, Donatsring 20, 09599, Freiberg, Deutschland.

Background: Diseases of travelers upon returning home are described in numerous publications. However, we have limited data on the disease spectrum and the reasons for medical consultations during a trip.

Methods: Over the period of one year, we analyzed all patient visits to the inhouse medical center of a major 5‑star beach resort of an international chain in the Maldives. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00063-020-00691-2DOI Listing

'Shawl Sign' as a Paraneoplastic Dermatosis.

Cureus 2020 Apr 1;12(4):e7498. Epub 2020 Apr 1.

Family Medicine, Southern Illinois University School of Medicine, Springfield, USA.

Dermatomyositis (DM) is an idiopathic condition characterized by inflammation of muscles and skin lesions. It is often a paraneoplastic manifestation of internal malignancy. Hence, early recognition of this disorder is important. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195204PMC

Skin cancer risk and shade: comparing the risk of foresters with other outdoor workers.

J Eur Acad Dermatol Venereol 2020 May 4. Epub 2020 May 4.

Department of Dermatology and Allergy, Technical University of Munich, School of Medicine, Munich, Germany.

Background: Keratinocyte carcinoma (KC) is an increasingly important public health problem with an especially high prevalence in outdoor workers. In contrast to other occupations, foresters spend most of their outdoor time under the shade of trees.

Objectives: We aimed to compare the unique sun exposure patterns and sun protection behaviour of foresters with those of other outdoor workers and their relation to the KC risk. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jdv.16560DOI Listing

A Case of Short Stature and Severe Osteoporosis in a Young Man with Oculocutaneous Albinism: Syndrome or Coincidence?

Authors:
Samson O Oyibo

Cureus 2020 Apr 24;12(4):e7817. Epub 2020 Apr 24.

Internal Medicine, Peterborough City Hospital, Peterborough, GBR.

Oculocutaneous albinism (OCA) is a rare autosomal recessive congenital condition characterized by reduced or absent production of the pigment melanin by melanocytes. The affected individuals have increased susceptibility to sunburn and skin cancers. Osteoporosis is a disease entity characterized by the progressive loss of bone mineral density and the deterioration of bone micro-architecture, leading to an increased risk of developing low-trauma fractures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186092PMC

Melanoma Epidemiology and Sun Exposure.

Acta Derm Venereol 2020 Jun;100(11):adv00136

The worldwide incidence of melanoma has increased rapidly over the last 50 years. Melanoma is the most common cancer found in the young adult population, and its incidence is very high among geriatric populations. The incidence of melanoma varies by sex, and this factor is also associated with differences in the anatomical site melanoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2340/00015555-3491DOI Listing

Melanoma Genomics.

Acta Derm Venereol 2020 Jun;100(11):adv00138

The incidence of cutaneous melanoma continues to increase in pale skinned peoples in Europe and elsewhere. Epidemiological studies identified genetically determined phenotypes such as pale skin, freckles and red hair, and sunburn as risk factors for this cancer. The development of many melanocytic naevi is also genetically determined and a strong melanoma risk phenotype. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2340/00015555-3493DOI Listing

Impact of pre-departure preparation on the health and wellbeing of Australian gap year travellers.

Travel Med Infect Dis 2020 Apr 20:101682. Epub 2020 Apr 20.

Travel Medicine Alliance Clinics, Brisbane, Australia.

Background: Medical problems are prevalent among young travellers. A quasi-experimental study was conducted to investigate the impact of country-specific pre-departure preparation in the occurrence of medical and psychological problems among Australian gap year.

Methods: Participants were recruited during two periods, 2013-14 and 2017-18 from an organisation that specialises in gap year placements. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tmaid.2020.101682DOI Listing

Glycosyl flavones from Humulus japonicus suppress MMP-1 production via decreasing oxidative stress in UVB irradiated human dermal fibroblasts.

BMB Rep 2020 Apr 22. Epub 2020 Apr 22.

Smart Farm Research Center, Korea Institute of Science and Technology (KIST) Gangneung Institute, Gangwon, Korea.

Exposure to Ultraviolet (UV) light induces photoaging of skin, leading to wrinkles and sunburn. The perennial herb Humulus japonicus, widely distributed in Asia, is known to have anti-inflammatory, antimicrobial, and antioxidant effects. However, the physiological activities of isolated compounds from H. Read More

View Article

Download full-text PDF

Source

Sunscreen for Adventure Travel: Use Sun Protection Factor (SPF) 50 or Higher.

Authors:
Ken Zafren

J Travel Med 2020 Apr 17. Epub 2020 Apr 17.

Department of Emergency Medicine, Alaska Native Medical Center, Anchorage, AK, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jtm/taaa048DOI Listing

Ultraviolet Radiation Exposure, Risk, and Protection in Military and Outdoor Athletes.

Curr Sports Med Rep 2020 Apr;19(4):137-141

Department of Kinesiology, The Pennsylvania State University, University Park, PA.

Overexposure to ultraviolet radiation (UVR) from the sun is associated with deleterious health effects including, but not limited to, increased risk of skin cancers. Military personnel and those who participate in outdoor exercise or sports represent two potential populations at elevated risk of negative health consequences of UVR exposure due to large amounts of time spent outdoors, often in harsh UVR environments. Despite exposure to high and/or frequent doses of UVR in recreational and tactical athletes, adequate sun-protection practices are often disregarded or not well understood by many within these at-risk populations, resulting in heightened risk of negative UVR effects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1249/JSR.0000000000000702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158759PMC

Trends in emergency department visits due to sunburn and factors associated with severe sunburns in the United States.

Arch Dermatol Res 2020 Apr 9. Epub 2020 Apr 9.

Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

Little is known regarding the burden of sunburns leading to emergency department (ED) visits in the United States (US). The objectives of this research were to characterize the burden of sunburn ED visits, investigate predictors of severe sunburns, and evaluate risk factors for increased cost of care in patients presenting to the ED for sunburn. In this nationally representative cross-sectional study of the National Emergency Department Sample (NEDS, 2013-2015), multivariable models were created to evaluate adjusted odds for sunburn ED visits, seasonal/regional variation in sunburn ED visits, adjusted odds for second and third degree sunburns, and risk factors for increased ED expenditure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02073-2DOI Listing

UV radiation recruits CD4GATA3 and CD8GATA3 T cells while altering the lipid microenvironment following inflammatory resolution in human skin .

Clin Transl Immunology 2020 Apr 2;9(4):e01104. Epub 2020 Apr 2.

Centre for Dermatology Research Division of Musculoskeletal and Dermatological Sciences Faculty of Biology, Medicine and Health School of Biological Sciences Manchester Academic Health Science Centre The University of Manchester and Salford Royal NHS Foundation Trust Manchester UK.

Objectives: Solar ultraviolet radiation (UVR) has major adverse effects on human health. While the mechanisms responsible for induction of UVR-induced inflammation are well-documented, the mediation of its resolution and longer-term adaptive homeostasis is unknown. Therefore, we examined the skin immune and lipid profile over time following UVR inflammation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cti2.1104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114692PMC

Sunscreen Use among a Population of Saudi University Students.

Dermatol Res Pract 2020 16;2020:4732721. Epub 2020 Mar 16.

College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Results: A total of 1,011 students were enrolled. Approximately half were males ( = 510). Half of the students used sunscreen ( = 515, 51%). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/4732721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102484PMC

Rosemary Diterpenes and Flavanone Aglycones Provide Improved Genoprotection against UV-Induced DNA Damage in a Human Skin Cell Model.

Antioxidants (Basel) 2020 Mar 20;9(3). Epub 2020 Mar 20.

Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Instituto de Biología Molecular y Celular (IBMC), Miguel Hernández University (UMH), 03202 Elche, Spain.

Overexposure to solar ultraviolet (UV) radiation is the major cause of a variety of cutaneous disorders, including sunburn, photoaging, and skin cancers. UVB radiation (290-320 nm) causes multiple forms of DNA damage, p53 induction, protein and lipid oxidation, and the generation of harmful reactive oxygen species (ROS). In recent years, botanicals containing polyphenols with antioxidant and anti-inflammatory properties as skin photoprotective agents have emerged. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/antiox9030255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139908PMC

Apple Extract ( sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin.

Rejuvenation Res 2020 May 18. Epub 2020 May 18.

Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

The skin is exposed to the solar ultraviolet B (UVB) radiation, which leads to the formation of several types of skin damage responsible for cancer initiation and aging. sp. is a genus of apples, which are a good source of polyphenolic compounds. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/rej.2019.2219DOI Listing

"Efficacy and safety of Liangxue Jiedu decoction for the treatment of progressive psoriasis vulgaris: a multicenter, randomized, controlled study".

J Tradit Chin Med 2020 Apr;40(2):296-304

Dermatology Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.

Objective: To determine the clinical efficacy and safety of Liangxue Jiedu decoction (LJD) for the treatment of progressive psoriasis vulgaris and to provide the basis for the development of a standardized treatment protocol for psoriasis vulgaris.

Methods: In this multicenter, randomized, controlled study, patients with blood-heat type psoriasis were randomly assigned to receive either Chinese herbal medicine (LJD; treatment group) or Western Medicine (cetirizine hydrochloride, vitamin C, and vitamin B complex; control group). Psoriasis Area and Severity Index (PASI) scores were calculated in addition to the number of patients who achieved ≥ 50% or ≥ 75% improvement in PASI score from baseline. Read More

View Article

Download full-text PDF

Source
April 2020
0.667 Impact Factor

[Blister formation on the back of the hand : Not an ordinary sunburn].

Hautarzt 2020 Mar 30. Epub 2020 Mar 30.

Hautklinik, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00105-020-04576-5DOI Listing

Protection-adjusted UV dose estimated for body areas: Daily self-reported sun protection modification of wearable UV sensor dose.

Photodermatol Photoimmunol Photomed 2020 Mar 18. Epub 2020 Mar 18.

Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.

Background: During the last 20 years, 50% of adults with sun-sensitive skin have sunburned annually. Reducing the proportion of people who sunburn requires understanding the circumstances and outdoor activities during which at-risk people sunburn.

Methods: A 7-day observational study of melanoma survivors (n = 20) and young adult first-degree relatives of melanoma survivors (FDRs) (n = 20) captured daily UV exposure, sun protection, and sunburns during spring and summer in the Midwest of the United States (latitude 41. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/phpp.12557DOI Listing
March 2020
1.295 Impact Factor

An approach to design a wristwatch for the protection of the human skin damage induced by ultraviolet and infrared radiations.

Photodermatol Photoimmunol Photomed 2020 Mar 18. Epub 2020 Mar 18.

Department of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Background: Ultraviolet radiations (UV) absorbed by the skin can drive photochemical reactions which range from sunburn to skin cancer. The repeated exposure to Infrared radiations (IR) induces the heat into the skin, which causes dehydration and erythema as an immediate effect. This heat activates the metalloproteinase enzyme that reduces the number of procollagen and collagen fibers in the dermal skin, which results premature skin aging. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/phpp.12551DOI Listing

Oxidations in white grape (Vitis vinifera L.) skins: Comparison between ripening process and photooxidative sunburn symptoms.

Plant Physiol Biochem 2020 May 6;150:270-278. Epub 2020 Mar 6.

Department of Agricultural and Environmental Sciences - Production, Landscape, Agroenergy, Università degli Studi di Milano, Via G. Celoria 2, 20133, Milan, Italy.

Oxidations in grape berries are gaining major interest as they affect grape characteristics and quality. Considering berries, Reactive Oxygen Species are involved in the responses to both ripening process and stresses, including photooxidative sunburn. Redox metabolism involves a multitude of chemical and enzymatic reactions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.plaphy.2020.03.003DOI Listing

Exogenous pyruvate facilitates ultraviolet B-induced DNA damage repair by promoting H3K9 acetylation in keratinocytes and melanocytes.

Biomed Pharmacother 2020 Jun 9;126:110082. Epub 2020 Mar 9.

Institute of TCM Surgery, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. Electronic address:

Ultraviolet radiation (UVR) is the major cause of numerous skin diseases, including sunburn, skin aging, and skin cancers. Pyruvate is a key intermediate in cellular metabolic pathways, which has shown protective effects against oxidative stress and apoptosis, but its role in UV protection remains unclear. Here we established human and mice in vivo model and found that pyruvate protects both human and mouse skin from UVB-induced DNA damage. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopha.2020.110082DOI Listing
June 2020
2.023 Impact Factor

When to suspect a non-melanoma skin cancer.

BMJ 2020 Mar 11;368:m692. Epub 2020 Mar 11.

Department of Dermatology, Nottingham NHS Treatment Centre, Nottingham NG7 2FT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.m692DOI Listing

"Live Sun Smart!" Testing the effectiveness of a sun safety program for middle schoolers.

Pediatr Dermatol 2020 May 10;37(3):504-509. Epub 2020 Mar 10.

Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Background: Skin cancer is a well-recognized public health issue, and primary prevention is the most effective strategy for reducing skin cancer risk. The current recommendations are that behavioral counseling for sun safety measures is most beneficial and effective for children and adolescents and that targeting this population at primary and middle schools is the ideal intervention strategy to increase sun-protective behaviors and reduce UV exposure, sunburn incidence, and formation of new moles. Numerous studies on the effectiveness of school-based sun safety interventions among elementary and middle school students have shown an increase in sun safety knowledge, attitudes, and behaviors following the intervention. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.14141DOI Listing

Incidence and public health burden of sunburn among beachgoers in the United States.

Prev Med 2020 May 3;134:106047. Epub 2020 Mar 3.

Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive M/D B243-01, Research Triangle Park, NC 27709, USA. Electronic address:

The beach environment creates many barriers to effective sun protection, putting beachgoers at risk for sunburn, a well-established risk factor for skin cancer. Our objective was to estimate incidence of sunburn among beachgoers and evaluate the relationship between sunburn incidence and sun-protective behaviors. A secondary analysis, of prospective cohorts at 12 locations within the U. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ypmed.2020.106047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271251PMC

Nectandra cuspidata fraction and the isolated polyphenols protect fibroblasts and hairless mice skin from UVB-induced inflammation and oxidative stress.

J Photochem Photobiol B 2020 Apr 19;205:111824. Epub 2020 Feb 19.

Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Estadual de Maringá, Avenida Colombo, 5790, 87020-900 Maringá, Paraná, Brazil. Electronic address:

Excessive exposure to UVB radiation can lead to oxidative and inflammatory damage that compromises the cutaneous integrity. The application on the skin of photochemoprotective products is considered a relevant approach for the prevention of oxidative damage. In this study the in vitro and in vivo photochemoprotective effects of antioxidant plant materials obtained from the leaves of Nectandra cuspidata Nees following UVB irradiation were evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jphotobiol.2020.111824DOI Listing

Differences in Risk Factors for Melanoma in Young and Middle-aged Higher-risk Patients.

In Vivo 2020 Mar-Apr;34(2):703-708

Department of Plastic Surgery, Faculty of Medicine and Health Technology and Tampere University Hospital, Tampere University, Tampere, Finland.

Background/aim: Differences in risk factors for melanoma between young adults (18-39 years) and middle-aged (40-60 years) are not well documented. In this study, we aimed to determine differences in risk factors and characteristics of melanoma between these groups.

Patients And Methods: This retrospective study is a review on 330 patients, including 250 middle-aged and 80 young adults, during the period 2006-2016 in the Tampere university hospital, in Finland. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/invivo.11827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157841PMC
December 2019

Using Social Media to Determine the Affective and Cognitive Components of Tweets about Sunburn.

Dermatology 2020 27;236(2):75-80. Epub 2020 Feb 27.

School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia,

Background: The relationship between social media usage and the public's expressions of sunburn remains unexplored. This study is a content analysis of Twitter that was performed to identify the public's expressions, perceptions, and attitudes towards sunburn.

Methods: Qualitative content analysis was conducted on tweets by Australian Twitter users during January 2007 and January 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000506102DOI Listing
February 2020

Effects of oligomeric proanthocyanidins (OPCs) of red wine to improve skin whitening and moisturizing in healthy women - a placebo-controlled randomized double-blind parallel group comparative study.

Eur Rev Med Pharmacol Sci 2020 Feb;24(3):1571-1584

Suntory Global Innovation Center Ltd., Kyoto, Japan.

Objective: This study was undertaken to evaluate the effects of red wine from grapes oligomeric procyanidins (OPCs) intake on skin color and skin moisture in Japanese healthy women. The purpose of this study was to improve skin condition, with the primary endpoint set to improve sunburn by ultraviolet (UV) and the secondary endpoint set to improve dryness.

Patients And Methods: A randomized, placebo-controlled, double-blind, parallel-group study was conducted on 100 subjects (30 to 59 years of age). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26355/eurrev_202002_20215DOI Listing
February 2020

Kawasaki Disease Following Severe Sunburn Injury.

Front Pediatr 2020 28;8. Epub 2020 Jan 28.

Department of Pediatrics, Saiseikai Shimonoseki General Hospital, Yamaguchi, Japan.

Although an etiology of Kawasaki disease (KD) is unknown, an aberrant innate immune system in predisposed individuals has been proposed to play a key role in the development of KD vasculitis. Various etiological pathogens have been proposed as the trigger of KD and a scaled injury preceding symptom onset has been reported as one of them. Here, we report a 17-month-old Japanese female who was hospitalized due to high fever lasting for 4 days with infection ruled out as a cause. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fped.2020.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997125PMC
January 2020

Safety and Tolerability of Sarecycline for the Treatment of Acne Vulgaris: Results from a Phase III, Multicenter, Open-Label Study and a Phase I Phototoxicity Study.

J Clin Aesthet Dermatol 2019 Nov 1;12(11):E53-E62. Epub 2019 Nov 1.

Dr. Pariser is with the Eastern Virginia Medical School and Virginia Clinical Research, Inc. in Norfolk, Virginia.

We sought to evaluate the safety, tolerability, and patterns of use for the once-daily oral, narrow-spectrum antibiotic sarecycline in patients with moderate-to-severe acne vulgaris during a 40-week Phase III, multicenter, open-label extension study. Patients aged nine years or older with moderate-to-severe acne who completed one of two prior Phase III, double-blind, placebo-controlled, 12-week trials in which they received sarecycline 1.5mg/kg/day or placebo were included. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937166PMC
November 2019

The effects of UVB irradiance on vitiligo phototherapy and UVB-induced photocarcinogenesis.

Photodermatol Photoimmunol Photomed 2020 Feb 5. Epub 2020 Feb 5.

Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Phototherapy is the most commonly used modality for repigmenting vitiligo. Currently, UVB emitting devices, including narrow-band UVB (NBUVB) and excimer laser/light, are considered as the treatment of choice. While emitting wavelengths at close proximity, excimer lights emit higher irradiance (HI; W/m ) compared to NBUVB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/phpp.12536DOI Listing
February 2020

Sun protection education for adolescents: a feasibility study of a wait-list controlled trial of an intervention involving a presentation, action planning, and SMS messages and using objective measurement of sun exposure.

BMC Public Health 2020 Jan 30;20(1):131. Epub 2020 Jan 30.

Faculty of Kinesiology, University of New Brunswick, Fredericton, Canada.

Background: People increase their risk of melanoma unless they are protected from the harmful effects of sun exposure during childhood and adolescence. We aimed to assess the feasibility of a three-component sun protection intervention- presentation, action planning, and SMS messages - and trial parameters.

Methods: This feasibility wait-list trial was conducted in the United Kingdom in 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12889-020-8265-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990594PMC
January 2020

Beach Feet: A Sand-associated Thermal Injury to the Soles of the Feet and the Plantar Aspect of the Toes.

Authors:
Philip R Cohen

Cureus 2019 Dec 20;11(12):e6429. Epub 2019 Dec 20.

Dermatology, San Diego Family Dermatology, San Diego, USA.

Athletes may develop sports-related dermatoses. Indeed, participants of aquatic-associated sports can experience dermatologic conditions that affect their feet when they play barefooted on the beach. These disorders are variable in etiology and include traumatic injury to the unprotected feet and toes, penetration of organisms (such as hookworm larva and schistosomiasis cercaria) into the feet and toes, and ultraviolet radiation-related maladies such as an acute phototoxic reaction (sunburn) and thermal injury from contact with hot sand. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.6429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970441PMC
December 2019

Topical transient receptor potential ankyrin 1 antagonist treatment attenuates nociception and inflammation in an ultraviolet B radiation-induced burn model in mice.

J Dermatol Sci 2020 Feb 18;97(2):135-142. Epub 2020 Jan 18.

Neurotoxicity and Psychopharmacology Laboratory, Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address:

Background: Ultraviolet B (UVB) radiation exposure promotes sunburn and thereby acute and chronic inflammatory processes, contributing to pain development and maintenance. New therapeutic alternatives are necessary because typical treatments can cause adverse effects. An attractive alternative would be to target the transient receptor potential ankyrin 1 (TRPA1), a calcium-permeable, non-selective cation channel, which is involved in a variety of inflammatory pain models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2020.01.005DOI Listing
February 2020

Smartphone Application-Enabled Apple Fruit Surface Temperature Monitoring Tool for In-Field and Real-Time Sunburn Susceptibility Prediction.

Sensors (Basel) 2020 Jan 22;20(3). Epub 2020 Jan 22.

Department of Biological Systems Engineering, Center for Precision and Automated Agricultural Systems, Washington State University, Prosser, WA 99350, USA.

Heat stress and resulting sunburn is a major abiotic stress in perineal specialty crops. For example, such stress to the maturing fruits on apple tree canopies can cause several physiological disorders that result in considerable crop losses and reduced marketability of the produce. Thus, there is a critical technological need to effectively monitor the abiotic stress under field conditions for timely actuation of remedial measures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/s20030608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038344PMC
January 2020