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J Fr Ophtalmol 2019 Mar 26. Epub 2019 Mar 26.

Département d'ophtalmologie, DHU vision et handicaps, hôpital Pitié-Salpêtrière, 47-92, boulevard de l'Hopital, 75013 Paris, France. Electronic address:

Meningiomas represent about 20% of intracranial tumors. Involvement of the medial sphenoid wing includes anterior clinoid, cavernous sinus and superior orbital fissure meningiomas. Due to the proximity of these tumors to the optic nerve, typically progressive unilateral vision loss, over several months to years, is the classic clinical presentation. Read More

BMJ Case Rep 2019 Mar 9;12(3). Epub 2019 Mar 9.

Kasturba Medical College, Mangalore (Manipal Academy Of Higher Education), Mangalore, India.

Vestn Oftalmol 2019;135(1):47-52

Khabarovsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 211 Tikhookeanskaia St., Khabarovsk, Russian Federation, 680033.

One of the most severe urgent conditions of the eye capable of leading to untreatable blindness is an acute attack of glaucoma. This condition is an acute decompensation of eye hydrodynamics, which develops with primary angle-closure glaucoma (PACG). Detectability of PACG is only high at the sudden development of an acute attack, which can cause a sharp decrease or even irreversible loss of vision. Read More

Aesthet Surg J 2019 Feb 21. Epub 2019 Feb 21.

Private practice in Los Angeles, CA.

Background: Sudden loss of vision secondary to filler treatments is a rare but catastrophic complication.

Objective: To update the published cases of blindness after filler injection which have occurred since we published our review of 98 cases in 2015, and to discuss prevention and management strategies.

Methods: A literature review was performed to identify all cases of visual complications from filler between January 2015 and September 2018. Read More

Arch Soc Esp Oftalmol 2019 Feb 12. Epub 2019 Feb 12.

Consorcio Hospital General Universitario de Valencia, Valencia, España.

Digital subtraction angiography (DSA) is a technique used in interventional radiology for the diagnosis of vascular cerebral conditions. Central retinal artery occlusion (CRAO) is a complication of endovascular procedures that involve atherosclerotic plaque removal with subsequent embolisation. The case is presented on a patient who noticed a sudden vision loss during a DSA. Read More

Medicine (Baltimore) 2019 Feb;98(7):e14470

Department of Neurology.

Rationale: Intravascular large B-cell lymphoma (IVLBCL) is a type of malignant lymphoma in which neoplastic B cells proliferate selectively within the lumina of small- and medium-sized vessels. Patients with IVLBCL frequently develop neurological manifestations during their disease course. Patients are known to often develop various neurological manifestations, but there are only a few reports of IVLBCL whose initial symptoms are deafness and/or disequilibrium. Read More

Arq Bras Oftalmol 2019 Mar-Apr;82(2):155-157

Department of Neuro-radiology, Sheikh Khalifa Hospital, Abu Dhabi, UAE.

Numerous studies have reported on structural vascular anomalies and ischemia associated with neurofibromatosis type 1 that are thought to stem from dysfunction of neurofibromin, the neurofibromatosis type 1 protein. Documented cases of associated antiphospholipid syndrome fulfilling the accepted diagnostic criteria are exceptionally rare, with only three cases reported in the literature. Here, we report on a patient with neurofibromatosis type 1 and a history of spontaneous abortions presenting with sudden vision loss in the right eye and swelling of the optic nerve head. Read More

Arch Soc Esp Oftalmol 2019 Feb 1. Epub 2019 Feb 1.

Servicio de Medicina Interna, Hospital Universitario 12 de Octubre, Madrid, España.

A 57-year-old man with miliary tuberculosis reported visual loss in his right eye, a month after starting a four-drug antituberculous treatment regimen. On exploration, an inferior segmental optic disc edema was objectived and it was attributed to ischemic aetiology. Ethambutol was withdrawn and 60mg of oral prednisone daily were given with a tapering dosage. Read More

Eye (Lond) 2019 Jan 24. Epub 2019 Jan 24.

Centre Hospitalier National d'Ophtalmologie des 15/20, Service du Pr. NORDMANN, Paris, France.

Background/objectives: To assess the risk of immediate sudden visual loss ("wipe-out" phenomenon) following non-penetrating deep sclerectomy (NPDS) for end-stages glaucoma within the first 6-months postoperative period.

Subjects/methods: Monocenter database study. We reviewed the results for 73 eyes with severe or end-stage glaucoma that underwent NPDS. Read More

Dermatol Online J 2018 Oct 15;24(10). Epub 2018 Oct 15.

Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado Dermatology Service, US Department of Veteran Affairs, Eastern Colorado Health Care System, Denver, Colorado.

Flickr, which was launched in 2004, is one of the oldest photo-sharing services online. The company, which was once at the forefront of the internet social media explosion, lost users and received criticism as its repeated acquisitions by other companies forced users to adapt to new owners. Now facing another acquisition by the online photo-sharing service SmugMug, the future is uncertain again for the once popular internet and mobile application service. Read More

Audiol Neurootol 2018 10;23(6):309-315. Epub 2019 Jan 10.

Department of Otolaryngology, Head and Neck Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China,

Objective: To explore the effectiveness and safety of round window niche drilling combined with intratympanic methylprednisolone injection for the salvage treatment of sudden sensorineural hearing loss (SSNHL) and its associated tinnitus after failed primary treatment.

Method: SSNHL patients who showed a less than 10-dB improvement of pure-tone average after receiving standard systemic treatment and intratympanic steroid injection were enrolled. All included patients were randomly divided into two groups (control and study). Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):893-897

Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences Peking Union Medical College, Beijing 100730, China.

Dynamic visual acuity (DVA) is defined as the visual acuity when there are relative movements between subjects and visual targets. The purpose of this study was to discuss the correlation between bedside DVA test and other examinations of vestibular function, and to assess the value of DVA test for clinical diagnosis. Retrospective analysis of 323 cases with peripheral vestibular disorder, and analyzing the correlation between bedside DVA results and caloric test were performed. Read More

BMC Res Notes 2018 Dec 20;11(1):911. Epub 2018 Dec 20.

Dipartimento di Scienze Mediche di Base, Neuroscienze e Organi di Senso - Università degli Studi Aldo Moro, Piazza G. Cesare, 70124, Bari, Italy.

Objectives: Leber's hereditary optic neuropathy (LHON) is a mitochondrial genetic disease characterized by a variable and reduced penetrance. Individuals carrying a primary LHON-causing mitochondrial DNA (mtDNA) mutation may either remain asymptomatic lifelong, as unaffected carriers, or develop sudden central visual loss that rapidly aggravates over some weeks. Over the years several genetic/environmental triggers able to modulate the risk of developing LHON have been proposed. Read More

Medicine (Baltimore) 2018 Dec;97(51):e13790

Department of Ophthalmology, Qilu Hospital.

Rationale: Open eye injury is one of the commonest ophthalmic emergencies, and when accompanied by intraorbital foreign bodies, the condition carries a poor prognosis.

Patient Concerns: A 28-year-old man presented to the emergency department of our hospital complaining of sudden painful loss of vision in the left eye after he hammered an iron plate.

Diagnosis: The ocular examination revealed a 4-mm full thickness scleral laceration with prolapsed uveal tissue, a traumatic cataract. Read More

Clin Exp Emerg Med 2018 Dec 31;5(4):278-281. Epub 2018 Dec 31.

Department of Ophthalmology, Yonsei University Wonju College of Medicine, Wonju, Korea.

Central retinal artery occlusion (CRAO) is considered an ophthalmologic emergency. The prognosis of this disease is very poor. Currently, there is no generally effective therapy available to treat CRAO. Read More

BMJ Case Rep 2018 Dec 7;11(1). Epub 2018 Dec 7.

Ophthalmology, UC Davis, Sacramento, California, USA.

A 28-year-old Caucasian man developed sudden painless vision loss in the right eye. He was diagnosed with optic neuritis. MRI showed white matter lesions consistent with multiple sclerosis (MS), but no optic nerve enhancement. Read More

Arch Soc Esp Oftalmol 2019 Mar 14;94(3):141-144. Epub 2018 Dec 14.

Departamento de Retina y Vítreo, Hospital General de México «Dr. Eduardo Liceaga», Ciudad de México, Estados Unidos Mexicanos. Electronic address:

Combined central retinal artery and vein occlusion is uncommon in adults and even more so in young people. The main origins are vasculitis and thromboembolic disorders. The prognosis is poor due to irreversible visual loss and the development of neovascular glaucoma (NVG). Read More

Medicine (Baltimore) 2018 Dec;97(50):e13594

Department of Ophthalmology, Sichuan University West China Hospital, Sichuan, China.

Rationale: Behcet disease is an autoimmune vasculitis, involving multiple systems and organs. It is often chronic and recurrent, and involves all levels of arteries and veins.

Patient Concerns: A 40-year-old Chinese male with sudden vision loss in his right eye for 3 days was reported. Read More

Retin Cases Brief Rep 2018 Nov 28. Epub 2018 Nov 28.

Department of Ophthalmology, Ministry of Education, Key Laboratory of Vision Loss and Restoration, Peking University Third Hospital, Beijing, China.

Purpose: Optic disk astrocytoma is a rare variant of congenital hamartoma, which is usually associated with tuberous sclerosis complex. Generally, it is stationary but in rare cases, it can show progressive growth and cause severe local complications.

Methods: Clinical-pathologic correlation. Read More

Zhonghua Yan Ke Za Zhi 2018 Dec;54(12):890-896

Tianjin Medical University, Clinical College of Ophthalmology, Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China.

To investigate the classification, possible risk factors, managements and clinical outcomes of suction loss in small incision lenticule extraction (SMILE). In this nested case control study, subjects undergoing SMILE surgery between September 2013 and September 2017 were enrolled in the study. Eyes suffered from suction loss were included in the suction loss group, and eyes without intraoperative complications and operated at the same date were included in the control group. Read More

Handb Clin Neurol 2018 ;159:385-401

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia. Electronic address:

Disorders of the inner-ear balance organs can be grouped by their manner of presentation into acute, episodic, or chronic vestibular syndromes. A sudden unilateral vestibular injury produces severe vertigo, nausea, and imbalance lasting days, known as the acute vestibular syndrome (AVS). A bedside head impulse and oculomotor examination helps separate vestibular neuritis, the more common and innocuous cause of AVS, from stroke. Read More

No Shinkei Geka 2018 Nov;46(11):1013-1020

Department of Neurosurgery(Omori), School of Medicine, Faculty of Medicine, Toho University.

Introduction: We report a rare case in which a pituitary tumor co-occurred with a giant mucocele. The mucocele's computed tomography(CT)values fell markedly when it collapsed, and we report the associated considerations.

Case: This case involved a 42-year-old male patient. Read More

BMC Ophthalmol 2018 Nov 16;18(1):299. Epub 2018 Nov 16.

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.

Background: Granulomatosis with polyangiitis (GPA), a necrotizing granulomatous disease, very rarely involves the central nervous system (CNS), particularly the pituitary. Delayed treatment may cause permanent bilateral blindness. We report an isolated case of pituitary GPA that manifested as a progressive bilateral temporal visual field (VF) defect and was diagnosed via pituitary biopsy. Read More

J Refract Surg 2018 Nov;34(11):775-778

Purpose: To report two cases of flap melting over corneal inlays for hyperopic correction several years after implantation.

Methods: The corneal inlay (+6.00 diopters [D]; PermaVision intracorneal lens; Anamed Inc. Read More

Turk J Ophthalmol 2018 Oct 31;48(5):258-261. Epub 2018 Oct 31.

Ege University Faculty of Medicine, Department of Ophthalmology, İzmir, Turkey.

Neuroretinitis characterized by optic disc edema and star-like exudates in the macula was detected in a patient who presented with sudden unilateral painless vision loss and had a history of raw meat consumption. The patient tested seropositive for . Combination therapy with steroid and albendazole resulted in an increase in visual acuity and complete resolution of clinical signs. Read More

Eur J Ophthalmol 2018 Nov 5:1120672118809579. Epub 2018 Nov 5.

3 Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Purpose:: To report a case of Evans syndrome with a vascular occlusive event leading to severe loss of vision.

Case Report:: A 12-year-old boy with Evans syndrome presented with painless acute loss of vision in the left eye during a period of remission from the disease. Examination showed visual acuity of hand motion in the left eye, left relative afferent pupillary defect, pale optic nerve head, and attenuated vessels. Read More

BMC Ophthalmol 2018 Oct 30;18(1):282. Epub 2018 Oct 30.

Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, 200040, China.

Background: Giant cell arteritis (GCA) is a systemic vasculitis of medium and large-size vessels and can led to permanent visual loss in elderly patients. GCA is very rare among Asians. We report a Chinese patient presenting with acute bilateral anterior ischemic optic neuropathy, and the temporal artery biopsy proved the diagnose of GCA. Read More

BMC Ophthalmol 2018 Oct 26;18(1):278. Epub 2018 Oct 26.

Ocular Oftalmologia, Vitória, Brazil.

Background: Sudden visual loss and optic disc edema caused by optic neuritis (ON) is usually followed by significant visual recovery. However, little or no recovery occurs when the loss is caused by atypical ON, especially in patients with neuromyelitis optica (NMO). Optic disc drusen (ODD) is a cause of pseudo optic disc edema and may be a predisposing factor for non-arteritic anterior ischemic optic neuropathy (NAION), thereby mimicking atypical ON. Read More

Neuroimage Clin 2018 9;20:1010-1017. Epub 2018 Oct 9.

Neuro-otology Unit, Division of Brain Sciences, Charing Cross Hospital, Imperial College London, London W6 8RP, UK. Electronic address:

Vestibular neuritis (VN) is characterised by acute vertigo due to a sudden loss of unilateral vestibular function. A considerable proportion of VN patients proceed to develop chronic symptoms of dizziness, including visually induced dizziness, specifically during head turns. Here we investigated whether the development of such poor clinical outcomes following VN, is associated with abnormal visuo-vestibular cortical processing. Read More

World Neurosurg 2019 Jan 4;121:71-76. Epub 2018 Oct 4.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA. Electronic address:

Background: Symptoms that mimic pituitary apoplexy may be encountered with other neoplastic or infectious lesions.

Case Description: This 38-year-old man presented with severe sudden-onset headache and relapsing and remitting vision loss. Radiographic imaging studies demonstrated radiographic features of a hyperdense, hemorrhagic mass in the sellar region. Read More

Medicine (Baltimore) 2018 Oct;97(40):e12652

The First Hospital of Shanxi Medical University, Shanxi, PR China.

Rationale: Retinal artery occlusion (RAO) results in painless, catastrophic vision loss in a period of seconds. Optical coherence tomography angiography (OCTA) can image retinal microcirculation, which is helpful to evaluate treatment response during the follow-up period. Using a single case with central RAO, we report its retinal perfusion changes before and after treatment using OCTA. Read More

BMC Neurol 2018 Oct 4;18(1):165. Epub 2018 Oct 4.

Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Bangkok, 10400, Thailand.

Background: Herpes zoster ophthalmicus (HZO) is an inflammation related to reactivation of the latent varicella zoster virus (VZV), involving the ophthalmic branch of the trigeminal nerve. Optic neuritis (ON), a rare ocular complication following HZO, has been reported in 1.9% of HZO-affected eyes. Read More

J Bras Nefrol 2018 Sep 21. Epub 2018 Sep 21.

Universidade Federal de Viçosa, Departamento de Medicina e Enfermagem (DEM), Viçosa, MG, Brasil.

Introduction: The posterior reversible encephalopathy (PRES) syndrome encompasses a set of clinical-radiological findings associated with severe systemic arterial hypertension. This case report proposes to discuss the identification, diagnosis, and management of PRES in the pediatric population.

Case Presentation: Female patient, 10 years old, admitted to the emergency room with complaint of oliguria and generalized edema. Read More

Mol Genet Metab Rep 2018 Dec 25;17:38-41. Epub 2018 Sep 25.

National Centre for Inherited Metabolic Diseases, The Mater Misericordiae University Hospital, Dublin, Ireland.

Metalic prosthesis or occupational exposure are potential sources of systemic cobalt and chromium ion toxicity. The resultant multisystemic clinical presentation can lead to unnecessary investigations before a final etiologic diagnosis is made; with an average delay of a year or more commonly noted. A 58-year old man presented with cardiomyopathy, pericardial effusion, polycytaemia, polyneuropathy, visual impairment, sudden hearing loss and hypothyroidism over a 2-year period post a metal-on-polyethylene hip replacement surgery. Read More

Am J Ophthalmol Case Rep 2018 Dec 6;12:68-72. Epub 2018 Sep 6.

Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Purpose: Choroidal circulation hemodynamics in eyes with leukemia has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and choroidal thickness at the macula by using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) in a patient with leukemic retinopathy.

Observations: A 15-year-old boy presented with sudden central vision loss of his right eye. Read More

Seizure 2018 Oct 27;61:214-220. Epub 2018 Aug 27.

Department of Neurology, Oslo University Hospital - Rikshospitalet, PO Box 4950 Nydalen, 0424 Oslo, Norway; Faculty of Medicine, University of Oslo, PO Box 1072 Blindern, 0316 Oslo, Norway. Electronic address:

Purpose: The congenital long QT-syndrome (cLQTS) is characterized by ventricular arrhythmias, syncope and sudden cardiac death. Many LQTS genes are also expressed in the brain and emerging evidence suggest that cardiac channelopathies can also cause epilepsy. The aim of the study is to explore evidence of epilepsy and/or EEG abnormalities in a cohort with a genotyped diagnosis of LQT1 or LQT2. Read More

Ned Tijdschr Geneeskd 2018 08 30;162. Epub 2018 Aug 30.

Erasmus MC, afd. Oogheelkunde, Rotterdam.

A 29-year-old male presented at the ER with a red and painful left eye with sudden and progressive loss of vision within a week. His visual acuity was 1/60. Slit lamp investigation showed inflammatory cells throughout the anterior chamber and vitreous body, and a hyperaemic and swollen optic disc with retinal lesions, indicating a panuveitis combined with multifocal chorioretinitis. Read More

Eur J Ophthalmol 2018 Sep 12:1120672118799627. Epub 2018 Sep 12.

4 Vitreoretinal & Uveitis Department, Ophthalmica Clinic, Thessaloniki, Greece.

Introduction: The purpose of this report is to describe a case of Valsalva retinopathy in an intranasal cocaine user.

Case Report: A 49-year-old male presented with a history of sudden loss of vision and inferior visual field defect in his left eye. Clinical evaluation of the affected eye showed best corrected visual acuity of 20/25 and fundus examination revealed a preretinal hemorrhage superior to the disk with multiple intraretinal hemorrhages in and around the posterior pole. Read More

Rom J Ophthalmol 2018 Apr-Jun;62(2):166-174

Ophthalmology Clinic, "Agrippa Ionescu" Clinical Emergency Hospital, Bucharest, Romania.

Objective: We report one case of malignant high blood pressure with no systemic signs but with ocular complaints.

Methods: The paper presents the case of a 31-year-old male who complained of sudden loss of visual acuity in both eyes. The ophthalmological examination revealed bilateral papillary oedema. Read More

Turk J Emerg Med 2018 Sep 23;18(3):128-130. Epub 2017 Dec 23.

Giresun Prof. Dr. Ilhan Ozdemir Training and Research Hospital, Department of Emergency Medicine, Giresun, Turkey.

Background: The corpus callosum is the most important pathway enabling the exchange of information between the two cerebral hemispheres. Transient splenium lesions may develop in association with various pathologies and infections. We report a case presenting to the emergency department with transient visual loss and in which a transient lesion was determined in the splenium of the corpus callosum (SCC). Read More

Neuroscience 2018 Sep 1. Epub 2018 Sep 1.

Eaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston MA 02114, USA; Dept. of Otolaryngology, Harvard Medical School, Boston MA 02114, USA. Electronic address:

Debilitating perceptual disorders including tinnitus, hyperacusis, phantom limb pain and visual release hallucinations may reflect aberrant patterns of neural activity in central sensory pathways following a loss of peripheral sensory input. Here, we explore short- and long-term changes in gene expression that may contribute to hyperexcitability following a sudden, profound loss of auditory input from one ear. We used fluorescence in situ hybridization to quantify mRNA levels for genes encoding AMPA and GABA receptor subunits (Gria2 and Gabra1, respectively) in single neurons from the inferior colliculus (IC) and auditory cortex (ACtx). Read More

BMC Ophthalmol 2018 Aug 28;18(1):211. Epub 2018 Aug 28.

Department Of Ophthalmology, Faculty of Medicine, Taif University, Taif, Saudi Arabia.

Background: Sickle cell disease is a common inherited hemoglobinopathy and is associated with high morbidity and mortality. Vaso-occlusive crises commonly occur in individuals with SCD that results in high morbidity due to end-organ ischemia and infarction. These include splenic infarction, pulmonary involvement, acute chest syndrome, and orbital compression syndrome. Read More

Case Rep Ophthalmol 2018 May-Aug;9(2):348-356. Epub 2018 Jul 20.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Background: Recent immune therapy with checkpoint inhibitors (CPIs) has demonstrated remarkable antitumor effects on specific tumors, such as malignant lymphoma and non-small cell lung carcinoma. By contrast, CPIs cause an imbalance in the immune system, triggering a wide range of immunological side effects termed immune-related adverse effects (irAEs). Here, we report a rare case of optic neuritis and hypopituitarism during anti-programmed death-ligand 1 (PD-L1) antibody treatment. Read More

Ophthalmic Plast Reconstr Surg 2019 Jan/Feb;35(1):1-6

Ophthalmic Plastic and Reconstructive Surgery Service, Department of Ophthalmology of the Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, U.S.A.

Purpose: The objective of this study was to report a case of persistent and likely self-induced orbital emphysema (OE) following functional endoscopic sinus surgery with dislodgement of a previously placed orbital floor implant and to review the literature surrounding etiologies, pathophysiology, and management of OE.

Methods: Case report and review of the literature.

Results And Discussion: While blunt trauma resulting in disruption of the medial orbital wall is the most common cause of OE, there are an additional 25 underlying etiologies reported in the current literature. Read More

J Neurosci Res 2019 Jan 21;97(1):88-97. Epub 2018 Aug 21.

Institute of Human Genetics, Universität Regensburg, Regensburg, Germany.

Sorsby fundus dystrophy (SFD), an autosomal dominant, fully penetrant, degenerative disease of the macula, is manifested by symptoms of night blindness or sudden loss of visual acuity, usually in the third to fourth decades of life due to choroidal neovascularization (CNV). SFD is caused by specific mutations in the Tissue Inhibitor of Metalloproteinase-3, (TIMP3) gene. The predominant histo-pathological feature in the eyes of patients with SFD are confluent 20-30 m thick, amorphous deposits found between the basement membrane of the retinal pigment epithelium (RPE) and the inner collagenous layer of Bruch's membrane. Read More

J Neuroophthalmol 2018 Aug 15. Epub 2018 Aug 15.

Departments of Ophthalmology and Visual Sciences (ELA, JDT), Radiology (Neuroradiology) (EAL), and Neurology (JDT), Kellogg Eye Center, Ann Arbor, Michigan.

Background: Radiation-induced optic neuropathy (RON) is a form of delayed radionecrosis of the anterior visual pathways, which develops within months to years after external cranial irradiation and causes severe and irreversible vision loss. Small series reports have adequately documented its clinical features, but imaging characteristics have been less completely described.

Methods: We accrued cases from the University of Michigan Neuro-Ophthalmology Clinic files and from cases coded as "radiation optic neuropathy" at the University of Michigan Medical Center between 1994 and 2017. Read More

Am J Ophthalmol Case Rep 2018 Sep 20;11:149-152. Epub 2018 Jun 20.

Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, No. 95, Wen Chang Road, Shih Lin District, Taipei City, Taiwan.

Purpose: Amalric triangular sign is a rare phenomenon indicating choroidal ischemia. In this study, we reported a typical Amalric triangular sign in a case of central retinal artery occlusion (CRAO) combined with posterior ciliary artery (PCA) occlusion.

Observations: A 49-year-old women developed sudden visual loss in her left eye for one day. Read More

J Ophthalmic Vis Res 2018 Jul-Sep;13(3):351-354

Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To describe a case of ophthalmic artery occlusion and complete ophthalmoplegia after intralesional injection of a sclerosing agent into a subcutaneous hemangioma on the forehead.

Case Report: A 16-year-old girl underwent direct injection of 3 mL of sodium tetradecyl sulfate (Fibrovein) emulsion 1% (10 mg/mL) with a 23-gauge needle into a subcutaneous hemangioma on the forehead. Immediately after the injection, she developed sudden loss of vision and lid swelling of the left eye. Read More

Medicine (Baltimore) 2018 Aug;97(31):e11663

Department of Ophthalmology, National Defense Medical College, Saitama.

Rationale: Chronic uveitis with immunosuppressive agents could develop chronic herpetic retinitis with varicella-zoster virus (VZV) or herpes simplex virus (HSV). Ocular Epstein-Barr virus (EBV) infection develops uveitis and vitritis, but the clinical feature of EBV retinitis is not typical as a viral retinitis. EBV retinitis is rare, and only a few cases of EBV retinitis have been reported. Read More