257,515 results match your criteria Substance Abuse Treatment Prevention and Policy [Journal]


Intensity-modulated radiation therapy dose prescription and reporting: Sum and substance of the International Commission on Radiation Units and Measurements Report 83 for veterinary medicine.

Vet Radiol Ultrasound 2019 Feb 20. Epub 2019 Feb 20.

Division of Radiation Oncology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

Institutions' adherence to protocol, quality assurance, and radiation parameter reporting are key to adequately interpret and compare treatment outcomes in radiation oncology. In 2017, the editorial board for Veterinary Radiology & Ultrasound adapted author guidelines on "technical information for radiation therapy (RT)". These guidelines provide a framework to report the RT treatment process in manuscripts resulting from veterinary clinical trials. Read More

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http://dx.doi.org/10.1111/vru.12722DOI Listing
February 2019

Kratom exposures reported to United States poison control centers: 2011-2017.

Clin Toxicol (Phila) 2019 Feb 20:1-8. Epub 2019 Feb 20.

a Center for Injury Research and Policy , The Research Institute at Nationwide Children's Hospital , Columbus , OH , USA.

Context: Kratom, or Mitragyna speciosa, is a plant indigenous to Southeast Asia that has gained national attention in the United States for its increased use in the self-management of opioid withdrawal and pain, as well as for concerns about its safety.

Methods: This study analyzes exposures to kratom reported to poison control centers (PCCs) in the United States during 2011-2017 from the National Poison Data System (NPDS).

Discussion: From 2011 through 2017, 1807 kratom exposures were reported to United States PCCs. Read More

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http://dx.doi.org/10.1080/15563650.2019.1569236DOI Listing
February 2019

Homelessness among youth who identify as LGBTQ+: A systematic review.

J Clin Nurs 2019 Feb 20. Epub 2019 Feb 20.

School of Nursing and Midwifery, Queen's University Belfast, Northern Ireland, United Kingdom.

Aims And Objectives: To explore homelessness among lesbian, gay, bisexual, transgender, queer/questioning plus (LGBTQ+) youth and to identify their support and care requirements.

Background: LGBTQ+ youth face many health and societal challenges including issues related to homelessness.

Design: A systematic review of qualitative, quantitative and mixed methods studies. Read More

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http://dx.doi.org/10.1111/jocn.14818DOI Listing
February 2019

[Epidemiological study of mental health in the general population of Argentina].

Vertex 2018 Nov;XXIX(142):275-299

Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argentina.

In this paper we report the findings of the first "Epidemiological study of mental health in the general population of Argentina" in the framework of the World Mental Health Survey Initiative WHO / Harvard, in collaboration with the Faculty of Medicine of the University of Buenos Aires and the Asociación de Psiquiatras Argentinos (APSA) with funding from the Ministry of Health. Methodology: A multistage probabilistic household survey was conducted using the Composite International Diagnostic Interview (CIDI). The survey was conducted on 3,927 people aged 18 and over (no age limit), with fixed residence in one of the eight largest urban areas in the country (Buenos Aires, Córdoba, Corrientes-Resistencia, Mendoza, Neuquén, Rosario, Salta and Tucumán), representing approximately 50. Read More

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November 2018

[Jealousy and violence on university student intimate partners].

Vertex 2018 Nov;XXIX(142):245-254

Cátedra de Psiquiatría,Facultad de Ciencias Médicas, Universidad Nacional de La Plata.

The deleterious effect of dating violence motivates the empirical exploration of the influential factors that may be targets of prevention. The aims of this study are to investigate violence in couples of university students and explore their relationship with jealousy and other correlates. Method: with a cross-sectional design, we surveyed 84 medical students from the National University of La Plata, Argentina. Read More

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November 2018

Hydrogen gas promotes the adventitious rooting in cucumber under cadmium stress.

PLoS One 2019 20;14(2):e0212639. Epub 2019 Feb 20.

College of Horticulture, Gansu Agricultural University, Yinmen Village, Anning District, Lanzhou, PR China.

Hydrogen gas (H2) plays an important role in plant development and stress responses. Here, cucumber (Cucumis sativus L.) explants were used to investigate the roles of H2 in adventitious root development under cadmium (Cd) stress and its physiological mechanism. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212639PLOS
February 2019

Pesticide distribution and depletion kinetic determination in honey and beeswax: Model for pesticide occurrence and distribution in beehive products.

PLoS One 2019 20;14(2):e0212631. Epub 2019 Feb 20.

Department of Toxicology, Kimron Veterinary Institute, Bet Dagan, Israel.

Beehive products such as honey, beeswax and recently pollen have been regarded for many years as appropriate sentinels for environmental pesticide pollutions. However, despite yearly application of hundreds of approved pesticides in agricultural fields, only a minor fraction of these organic compounds were actually detected in honey and beeswax samples. This observation has led us to question the general suitability of beehive products as a sentinel for synthetic organic pesticides applied in the field. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212631PLOS
February 2019

Disorganized Attachment Interactions Among Young Adults With Borderline Personality Disorder, Other Diagnoses, and No Diagnosis.

J Pers Disord 2019 Feb 20:1-21. Epub 2019 Feb 20.

Harvard Medical School.

Theorists have suggested that attachment disorganization contributes to the development of borderline personality disorder (BPD). However, few studies have directly observed attachment-related interactions with parents. This study used a newly developed attachment-based coding system to examine whether individuals with BPD were more likely to exhibit disorganized interactions with their mothers than those with (a) other diagnoses (anxiety, depressive, or substance use diagnoses) or (b) no diagnosis. Read More

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http://dx.doi.org/10.1521/pedi_2019_33_408DOI Listing
February 2019

Generalized On-demand Production of Nanoparticle Monolayers on Arbitrary Solid Surfaces via Capillarity-mediated Inverse Transfer.

Nano Lett 2019 Feb 20. Epub 2019 Feb 20.

Century-old Langmuir monolayer deposition still represents the most convenient approach to the production of monolayers of colloidal nanoparticles on solid substrates for practical biological and chemical sensing applications. However, this approach simply yields arbitrarily-shaped large monolayers on a flat surface, and is strongly limited by substrate topography and interfacial energy. Here we describe a generalized and facile method of rapidly producing uniform monolayers of various colloidal nanoparticles on arbitrary solid substrates by using an ordinary capillary tube. Read More

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http://dx.doi.org/10.1021/acs.nanolett.9b00248DOI Listing
February 2019

Mobile Phone and Wearable Sensor-Based mHealth Approaches for Psychiatric Disorders and Symptoms: Systematic Review.

JMIR Ment Health 2019 Feb 20;6(2):e9819. Epub 2019 Feb 20.

Ab.Acus srl, Milano, Italy.

Background: Mobile Therapeutic Attention for Patients with Treatment-Resistant Schizophrenia (m-RESIST) is an EU Horizon 2020-funded project aimed at designing and validating an innovative therapeutic program for treatment-resistant schizophrenia. The program exploits information from mobile phones and wearable sensors for behavioral tracking to support intervention administration.

Objective: To systematically review original studies on sensor-based mHealth apps aimed at uncovering associations between sensor data and symptoms of psychiatric disorders in order to support the m-RESIST approach to assess effectiveness of behavioral monitoring in therapy. Read More

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http://dx.doi.org/10.2196/mental.9819DOI Listing
February 2019

Ustilobisorbicillinol A, a Cytotoxic Sorbyl-Containing Aromatic Polyketide from Ustilaginoidea virens.

Org Lett 2019 Feb 20. Epub 2019 Feb 20.

Department of Plant Pathology, College of Plant Protection , China Agricultural University , Beijing 100193 , China.

Ustilobisorbicillinol A (1), which is a novel bisorbicillinoid featuring a unique cage structure that incorporates one sorbicillinol and one sorbyl-containing phenanthrenone unit, was isolated from the culture of Ustilaginoidea virens. Three biogenetically related new metabolites (2-4) were also isolated. Their structures were elucidated by extensive spectroscopic analyses, including the C NMR and electronic circular dichroism (ECD) calculations for the configurational assignment. Read More

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http://dx.doi.org/10.1021/acs.orglett.8b04101DOI Listing
February 2019

Protective effect of mulberry (Morus atropurpurea) fruit against diphenoxylate-induced constipation in mice through the modulation of gut microbiota.

Food Funct 2019 Feb 20. Epub 2019 Feb 20.

Sericultural & Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences/Key Laboratory of Functional Foods, Ministry of Agriculture/Guangdong Key Laboratory of Agricultural Products Processing, China.

Mulberry (Morus atropurpurea) has long been used to treat gastro-intestinal ailments; however, the functional basis of its therapeutic effects remains unclear. The aim of this study was to measure the effects of mulberry (administered by gavage) on diphenoxylate-induced constipation in mice and elucidate the mechanisms underlying these effects using constipation and physicochemical indexes, histological morphology and 16S rDNA amplicon analysis of fecal microbiota. Sixty Kunming mice were randomly divided into the following six groups (n = 10 per group): normal control, constipation model, positive control, and low-, mid- and high-dose mulberry groups. Read More

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http://dx.doi.org/10.1039/c9fo00132hDOI Listing
February 2019

Risk, reversibility and resilience of brain circuitries linked to opioid dependence: A diffusion tensor imaging study of actively opioid-using subjects and three comparison groups.

Asian J Psychiatr 2019 Feb 13;40:107-115. Epub 2019 Feb 13.

Drug De-Addiction and Treatment Centre, Department of Psychiatry, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India. Electronic address:

Background: Drug addiction is linked with micro-structural changes in the fronto-striatal white matter (WM) tracts. However, little is known regarding causality (risk factor for subsequent drug use vs. effect of chronic drug use) and reversibility of such changes. Read More

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http://dx.doi.org/10.1016/j.ajp.2019.02.009DOI Listing
February 2019

Substance type moderates the longitudinal association between depression and substance use from pre-treatment through a 1-year follow-up.

Drug Alcohol Depend 2019 Feb 5;197:87-94. Epub 2019 Feb 5.

Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, 235 E. Cameron Avenue, Chapel Hill, NC 27514 USA. Electronic address:

Background: Research examining directionality of the relationship between depressive symptoms and substance use following treatment entry is limited. Furthermore, substances differ in their neurobiological effects on mood. The relationship between depression and substance use following treatment entry may be moderated by dependence on specific substances. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.002DOI Listing
February 2019

Co-occurring substance use and mental disorders among adults with opioid use disorder.

Drug Alcohol Depend 2019 Feb 14;197:78-82. Epub 2019 Feb 14.

Substance Abuse and Mental Health Services Administration, 5600 Fishers Lane, Rockville, MD 20857, USA.

Background: Co-occurring substance use and mental disorders among people with opioid use disorder (OUD) increase risk for morbidity and mortality. Addressing these co-occurring conditions is critical for improving treatment and health outcomes. There is limited recent research on the prevalence of co-occurring disorders, demographic characteristics associated with co-occurring disorders, and receipt of mental health and substance use treatment services among those with OUD. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2018.12.030DOI Listing
February 2019

The association between frequency of opioid misuse and opioid use disorder among youth and adults in the United States.

Drug Alcohol Depend 2019 Feb 13;197:73-77. Epub 2019 Feb 13.

Science Policy Branch, Office of Science Policy and Communications, National Institute on Drug Abuse, National Institutes of Health, 6001 Executive Blvd, Fifth Floor, Rockville, MD 20852, United States; Milken Institute School of Public Health, George Washington University, 950 New Hampshire Ave, NW, Washington DC 20052, United States.

Background: Studies have shown the frequency of drug misuse is important in the development of a substance use disorder, but little is known about this relationship in the context of opioid misuse and opioid use disorder and withdrawal symptoms.

Methods: Our study included 2694 civilian respondents from the United States 12 years and older who had misused prescription opioids in the past year from the 2014 National Survey on Drug Use and Health. Logistic regression was used to model the association between frequency of prescription opioid misuse and opioid use disorder and withdrawal symptoms, adjusting for age, sex, race/ethnicity, and income level. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.008DOI Listing
February 2019

Cytoprotective effects of olesoxime on isolated human pancreatic islets in order to attenuate apoptotic pathway.

Biomed Pharmacother 2019 Feb 19;112:108674. Epub 2019 Feb 19.

Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology-Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Background And Purpose: Islet transplantation is considered as a promising approach in the treatment of diabetes type 1. In this regard, optimal culture of the pancreatic islets is promising in the success of transplantation. In the present study, the effect of olesoxime, as an antiapoptotic substance, was evaluated on human islet culture. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.108674DOI Listing
February 2019

Application of an HPLC-MS/MS method for Teicoplanin drug substance and related impurities, part 2: Identity assignment of related impurities.

J Pharm Biomed Anal 2019 Feb 13;168:38-43. Epub 2019 Feb 13.

Department of Drug Sciences, University of Pavia, via Taramelli 12, I-27100 Pavia, Italy. Electronic address:

A liquid chromatographic MS-compatible method was applied to the structural elucidation of Teicoplanin for identification CRS components. The method, previously developed by our group, involves the use of LiChrospher 100 RP-18 column with a mobile phase composed of ammonium formate 25 mM at pH 6.00 and acetonitrile (ACN). Read More

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http://dx.doi.org/10.1016/j.jpba.2019.02.017DOI Listing
February 2019

Development and validation of a sensitive method for alkyl sulfonate genotoxic impurities determination in drug substances using gas chromatography coupled to triple quadrupole mass spectrometry.

J Pharm Biomed Anal 2018 Dec 30;168:23-29. Epub 2018 Dec 30.

School of Pharmacy, Fudan University, PR China. Electronic address:

Alkyl sulfonate esters have been widely concerned as genotoxic impurities (GTIs). A gas chromatography triple-quadrupole mass spectrometry (GC-MS/MS) method has been developed for trace determination of 9 commonly encountered sulfonate esters in drug substances. Three different solvents of acetonitrile (ACN), dichloromethane (DCM) and ethyl acetate (EtOAc) were evaluated as diluents to accommodate different solubilities of test articles and multiple reactions monitoring (MRM) mode was applied for quantitation of these 9 GTIs. Read More

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http://dx.doi.org/10.1016/j.jpba.2018.12.044DOI Listing
December 2018

Correlates of electronic cigarette use in the general population and among smokers in Australia - Findings from a nationally representative survey.

Addict Behav 2019 Feb 14;95:6-10. Epub 2019 Feb 14.

Centre for Youth Substance Abuse Research, Faculty of Health and Behavioural Sciences, The University of Queensland, Australia.

Aims: In Australia, sales of nicotine containing electronic cigarettes (also known as e-cigarette) are banned unless approved as a therapeutic good. The aims of this study were to estimate the prevalence of e-cigarette use and its correlates in Australia using a nationally representative survey.

Method: We analysed data from the largest drug use survey in Australia (the National Drug Strategy Household Survey [NDSHS]; N = 22,354). Read More

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http://dx.doi.org/10.1016/j.addbeh.2019.02.012DOI Listing
February 2019

Posttraumatic stress disorder and traumatic brain Injury: Sex differences in veterans.

Psychiatry Res 2019 Jan 31;274:105-111. Epub 2019 Jan 31.

Salisbury VA Health Care System, 1601 Brenner Ave, Salisbury, NC 28144, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC), 508 Fulton St, Durham, NC 27705, USA; Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Electronic address:

Around half of Iraq and Afghanistan war veterans with traumatic brain injury (TBI) have co-occurring posttraumatic stress disorder (PTSD). Research on the differences between male and female veterans with co-occurring PTSD/TBI is sparse. This study evaluated behavioral health differences between sexes with these conditions. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.01.097DOI Listing
January 2019

Simultaneous bioprecipitation of cadmium to cadmium sulfide nanoparticles and nitrogen fixation by Rhodopseudomonas palustris TN110.

Chemosphere 2019 Feb 13;223:455-464. Epub 2019 Feb 13.

Department of Civil and Environmental Engineering and Construction, University of Nevada, Las Vegas, NV 89154, USA. Electronic address:

This study investigated the abilities of a purple non-sulfur bacterium, Rhodopseudomonas palustris TN110 to bioremediate cadmium through the biosynthesis of CdS nanoparticles and to fix nitrogen simultaneously. Under microaerobic-light conditions, R. palustris TN110 synthesized CdS nanoparticles. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.02.051DOI Listing
February 2019

Adsorption of single and mixed haloacetonitriles on silica-based porous materials: Mechanisms and effects of porous structures.

J Environ Sci (China) 2019 May 4;79:346-360. Epub 2018 Oct 4.

Center of Excellence on Hazardous Substance Management (HSM), Chulalongkorn University, Bangkok 10330, Thailand; Department of Environmental Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand; Research unit Control of Emerging Micropollutants in Environment, Chulalongkorn University, Bangkok 10330, Thailand; Research Network of NANOTEC - CU on Environment, Bangkok 10330, Thailand. Electronic address:

Adsorption mechanisms and the role of different porous and crystalline structures on the removal of five haloacetonitriles (HANs) over hexagonal mesoporous silica (HMS), titanium substituted mesoporous silica (Ti-HMS), rod-shaped SBA-15 and microporous zeolite NaY were investigated. In addition, the effect of pH on adsorption mechanism and selective adsorption of five HANs individually and in an equimolar mixed solution were evaluated. The results indicated that the intraparticle diffusion rate constants of the mesoporous adsorbents were higher than that of the microporous NaY. Read More

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http://dx.doi.org/10.1016/j.jes.2018.09.009DOI Listing

Barriers Faced by Physicians in Screening for Substance Use Disorders Among Adolescents.

Psychiatr Serv 2019 Feb 20:appips201800427. Epub 2019 Feb 20.

IBM Watson Health, Bethesda, Maryland (Palmer, Karakus); RTI International, Rockville, Maryland (Mark).

Objective:: This study identifies key barriers faced by primary care providers (PCP) in implementation of screening, brief intervention, and referral to treatment (SBIRT) services for substance use disorders among adolescents.

Methods:: The authors used mixed methods, including 12 key informant interviews and a survey with 75 PCPs, to identify key barriers to PCP implementation of SBIRT services.

Results:: Time constraints, challenges related to parental involvement, a perceived lack of effectiveness of brief intervention services, and lack of training in providing brief intervention were barriers to screening and brief intervention. Read More

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http://dx.doi.org/10.1176/appi.ps.201800427DOI Listing
February 2019

Is placing a victim in the left lateral decubitus position an effective first aid intervention for acute oral poisoning? A systematic review.

Clin Toxicol (Phila) 2019 Feb 20:1-14. Epub 2019 Feb 20.

a Centre for Evidence-Based Practice (CEBaP) , Belgian Red Cross, Mechelen , Belgium.

Introduction: In acute oral poisoning, any first aid intervention that limits or delays the uptake of the ingested substance, and which can be performed by bystanders as first responders, might assist in reducing morbidity if a toxic substance has been ingested. The current recommendation by the International Federation of Red Cross/Red Crescent Societies is to place a victim in the left lateral decubitus position.

Objective: The aim of this PRISMA compliant systematic review is to assess whether the current recommendation by the International Federation of Red Cross/Red Crescent Societies decreases or delays the absorption of an orally ingested poison. Read More

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http://dx.doi.org/10.1080/15563650.2019.1574975DOI Listing
February 2019

Nine new compounds from the whole plants of Rehmannia henryi.

J Asian Nat Prod Res 2019 Feb 20:1-10. Epub 2019 Feb 20.

a State Key Laboratory of Bioactive Substance and Function of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.

Eight new iridoids (1-8) and an ionone glucoside (9), together with 31 known compounds (10-40), were isolated from the whole plants of Rehmannia henryi. The structures of these compounds were elucidated on the basis of their spectroscopic data and chemical evidence. Read More

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http://dx.doi.org/10.1080/10286020.2018.1541892DOI Listing
February 2019

Effects of ethyl ester supplementation to forage on short-term dry matter intake and preference by goats.

Arch Anim Nutr 2019 Feb 20:1-13. Epub 2019 Feb 20.

a Institute of Animal Science , University of Bonn , Bonn , Germany.

In whole-crop maize silages with atypical smell and decreased acceptance by ruminants, high concentrations of the volatile organic compounds ethyl acetate (EA) and ethyl lactate (EL) were detected. The aim of this study was to evaluate the impact of different concentrations of ethyl esters added to forage on preference and short-term feed intake of goats. In the first of three trials, whole-crop maize silage was supplemented with different concentrations of EA and EL and then vacuum-stored before use. Read More

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http://dx.doi.org/10.1080/1745039X.2019.1575656DOI Listing
February 2019

A case of methamphetamine use disorder presenting a condition of ultra-rapid cycler bipolar disorder.

SAGE Open Med Case Rep 2019 4;7:2050313X19827739. Epub 2019 Feb 4.

Department of Psychiatry, School of Medicine, Teikyo University, Tokyo, Japan.

Methamphetamine, a potent psychostimulant, may cause a condition of mood disorder among users. However, arguments concerning methamphetamine-induced mood disorder remain insufficient. This case study describes a male with methamphetamine-induced bipolar disorder not accompanied by psychotic symptoms, who twice in an 11-year treatment period, manifested an ultra-rapid cycler condition alternating between manic and depressive mood states with 3- to 7-day durations for each. Read More

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http://dx.doi.org/10.1177/2050313X19827739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365985PMC
February 2019

Attention-Deficit Hyperactivity Disorder Symptom Status in a Mixed Gender Population of Opioid-Maintained Prison Inmates.

Eur Addict Res 2019 Feb 18;25(2):80-92. Epub 2019 Feb 18.

Department for Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.

Objective: Attention-deficit hyperactivity disorder (ADHD) often coincides with substance abuse and delinquency. A sample of opioid-maintained inmates was assessed for symptoms of ADHD, substance abuse history, types of offense, psychiatric comorbidities, and psychopharmacological treatment using a standardized battery of instruments.

Method: Adult inmates (n = 133, mean age 35. Read More

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http://dx.doi.org/10.1159/000496351DOI Listing
February 2019

and activities of the riminophenazine TBI-166 against .

Antimicrob Agents Chemother 2019 Feb 19. Epub 2019 Feb 19.

Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute, and Beijing Chest Hospital, Capital Medical University, Beijing, China

The riminophenazine agent clofazimine (CFZ) is repurposed as an important component of the new short-course multidrug-resistant tuberculosis regimen and significantly shortens first-line regimen for drug-susceptible tuberculosis in mice. However, CFZ use is hampered by its unwelcome skin discoloration in patients. A new riminophenazine analog TBI-166 was selected as a potential next-generation antituberculosis riminophenazine following an extensive medicinal chemistry effort. Read More

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http://dx.doi.org/10.1128/AAC.02155-18DOI Listing
February 2019

Neuropsychiatric Genetics of African Populations-Psychosis (NeuroGAP-Psychosis): a case-control study protocol and GWAS in Ethiopia, Kenya, South Africa and Uganda.

BMJ Open 2019 Feb 19;9(2):e025469. Epub 2019 Feb 19.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Introduction: Schizophrenia and bipolar disorder account for a large proportion of the global burden of disease. Despite their enormous impact, little is known about their pathophysiology. Given the high heritability of schizophrenia and bipolar disorder, unbiased genetic studies offer the opportunity to gain insight into their neurobiology. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025469DOI Listing
February 2019

A trauma-informed substance use and sexual risk reduction intervention for young South African women: a mixed-methods feasibility study.

BMJ Open 2019 Feb 19;9(2):e024776. Epub 2019 Feb 19.

Substance Use and Gender Research (SUGAR) Program, Research Triangle Institute (RTI) International, Research Triangle Park, North Carolina, USA.

Objectives: Sexual and physical trauma and substance use are intersecting risks for HIV among young women. This study assesses the feasibility, acceptability and preliminary effects of a novel trauma-informed substance use and sexual risk reduction intervention for young South African women.

Design: A single arm feasibility test and qualitative interviews of participants. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024776DOI Listing
February 2019

HORYZONS trial: protocol for a randomised controlled trial of a moderated online social therapy to maintain treatment effects from first-episode psychosis services.

BMJ Open 2019 Feb 19;9(2):e024104. Epub 2019 Feb 19.

School of Behavioural and Health Sciences, Australian Catholic University, Melbourne, Victoria, Australia.

Introduction: Specialised early intervention services have demonstrated improved outcomes in first-episode psychosis (FEP); however, clinical gains may not be sustained after patients are transferred to regular care. Moreover, many patients with FEP remain socially isolated with poor functional outcomes. To address this, our multidisciplinary team has developed a moderated online social media therapy (HORYZONS) designed to enhance social functioning and maintain clinical gains from specialist FEP services. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024104DOI Listing
February 2019

The authors respond to comments on the use of secure care in youth.

CMAJ 2019 Feb;191(7):E199-E200

PhD student, Interdisciplinary Studies, Graduate Program, University of British, Columbia; Research Assistant, BC Centre, on Substance Use, Vancouver, BC.

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http://dx.doi.org/10.1503/cmaj.71589DOI Listing
February 2019

An ethical perspective on the use of secure care for youth with severe substance use.

CMAJ 2019 Feb;191(7):E195-E196

Director, Clinical Ethics Service, Provincial, Health Services Authority of British, Columbia, Vancouver, BC.

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http://dx.doi.org/10.1503/cmaj.71504DOI Listing
February 2019

Determination of residual organophosphorus thioester pesticides in agricultural products by chemical isotope-labelling liquid chromatography-tandem mass spectrometry coupled with in-syringe dispersive solid phase clean-up and in situ cleavage.

Anal Chim Acta 2019 May 21;1055:44-55. Epub 2018 Dec 21.

Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310014, China.

Chemical isotope labelling in combination with high-performance liquid chromatography-tandem mass spectrometry (CIL-HPLC-MS/MS) is a powerful method for quantitative profiling of targeted molecules. In the current work, we successfully developed a novel CIL-HPLC-MS/MS method for quantitative profiling of residual organophosphorus thioester pesticides (OPTPs) in agricultural products through the determination of the cleavage products of thiol (CP-thiol) compounds. In this method, we synthesized a novel pair of CIL reagents, i. Read More

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http://dx.doi.org/10.1016/j.aca.2018.12.039DOI Listing

Differential pulse polarographic investigation of micafungin and anidulafungin using a dropping mercury electrode.

Pharmazie 2019 Jan;74(1):18-22

The electrochemical behavior of the echinocandin antifungals anidulafungin (AF) and micafungin (MF) has been investigated by differential pulse polarography (DPP). The measurements were carried out in a supporting electrolyte solution consisting of Britton-Robinson buffer and methanol at various substance concentrations and pH values. An amperometric cell with a three electrode system consisting of a dropping mercury electrode (DME) as working electrode, an auxiliary platinum electrode and an Ag/AgCl reference electrode was used in all experiments. Read More

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http://dx.doi.org/10.1691/ph.2019.8680DOI Listing
January 2019

Environment risk factors have different impact on bipolar and psychotic disorders: an analysis of MHGP survey.

Psychol Med 2019 Feb 20:1-4. Epub 2019 Feb 20.

Univ. Lille, CNRS UMR 9193-PsyCHIC-SCALab, & CHU Lille, Pôle de Psychiatrie, Unité CURE,F-59000 Lille,France.

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http://dx.doi.org/10.1017/S0033291719000229DOI Listing
February 2019

Illicit substance use after release from prison among formerly incarcerated primary care patients: a cross-sectional study.

Addict Sci Clin Pract 2019 Feb 19;14(1). Epub 2019 Feb 19.

Albert Einstein College of Medicine, Bronx, NY, 10461, USA.

Background: More than 80% of people in jail or prison report having used illicit substances in their lifetimes. After release from incarceration, resumption of substance use carries risks, including parole revocation, exacerbation of mental health conditions, transmission of infectious diseases, and drug overdose.

Methods: This cross-sectional study used baseline data from the Transitions Clinic Network (TCN, www. Read More

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http://dx.doi.org/10.1186/s13722-019-0136-6DOI Listing
February 2019

Clinicians' perceptions for indicating and contra-indicating integrated treatment for SUD and comorbid PTSD, a vignette study.

Subst Abuse Treat Prev Policy 2019 Feb 19;14(1). Epub 2019 Feb 19.

NISPA, Nijmegen Institute for Scientist-Practitioners in Addiction, Radboud University, P.O. Box 6909, 6503, GK, Nijmegen, The Netherlands.

Background: Posttraumatic Stress Disorder (PTSD) is more common in patients with Substance Use Disorder (SUD) than in the general population. Although international guidelines recommend integrated treatment clinicians are still hesitant in offering integrated treatment and more concrete recommendations are needed. This study aims to contribute to a practice-based guideline through the exploration of practice-based decision criteria to determine the indication and treatment of SUD and PTSD. Read More

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http://dx.doi.org/10.1186/s13011-019-0194-5DOI Listing
February 2019

Effects of placebo on bench throw performance of Paralympic weightlifting athletes: a pilot study.

J Int Soc Sports Nutr 2019 Feb 19;16(1). Epub 2019 Feb 19.

Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiás, Brazil.

Background: The aim of the present study was to analyse the effects of placebo on bench throw performance in Paralympic weightlifting athletes.

Methods: The study involved four Paralympic weightlifting male athletes (age: 40.25 ± 9. Read More

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http://dx.doi.org/10.1186/s12970-019-0276-9DOI Listing
February 2019

On a Plasminogen Activator from Human Plasma.

Thromb Haemost 1979 Jul 18;42(1):1607-1614. Epub 2019 Feb 18.

The Institute de Hematologia e Immunologia, Habana, Cuba.

A plasminogen activating substance was purified from the dialysates of the eluates of glass adsorbed kallikrein from fresh human plasma, by chromatography on QAE-Sephadex A-50 and gel filtration in Sephadex G-25. The preparation was concentrated by lyophilization. Its electrophoretic mobility was found to be similar to that of prealbumin. Read More

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http://dx.doi.org/10.1055/s-0039-1681117DOI Listing

Occurrence of Bacterial Fruit Blotch of Watermelon Caused by Acidovorax avenae subsp. citrulli in the Eastern Mediterranean Region of Turkey.

Plant Dis 2006 Jun;90(6):829

Department of Genetics and Bioengineering, Faculty of Engineering and Architecture, Yeditepe University, 34755 Kayisdagi, Istanbul, Turkey.

Turkey has the second highest production level of watermelon (Citrullus lanatus L.) in the world, with 3.8 million tons produced in 2005. Read More

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http://dx.doi.org/10.1094/PD-90-0829CDOI Listing

Effect of Chinese Herb Extracts on Spore Germination of Oidium murrayae and Nature of Inhibitory Substance from Chinese Rhubarb.

Authors:
Y L Chu W C Ho W H Ko

Plant Dis 2006 Jul;90(7):858-861

Department of Plant Pathology, National Chung Hsing University, Taichung, Taiwan.

More than 21% of the Chinese herbs tested contained substances in their aqueous extracts inhibitory to conidial germination of the powdery mildew fungus Oidium murrayae. Extracts from Chinese rhubarb and Japanese knotweed were very effective in controlling powdery mildew on cucumber, pumpkin, and eggplant. The inhibitory substance in Chinese rhubarb was soluble in polar solvents and less soluble in nonpolar solvents. Read More

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http://dx.doi.org/10.1094/PD-90-0858DOI Listing

A Review of Epigenetics of PTSD in Comorbid Psychiatric Conditions.

Genes (Basel) 2019 Feb 13;10(2). Epub 2019 Feb 13.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA.

Post-traumatic stress disorder (PTSD) is an acquired psychiatric disorder with functionally impairing physiological and psychological symptoms following a traumatic exposure. Genetic, epigenetic, and environmental factors act together to determine both an individual's susceptibility to PTSD and its clinical phenotype. In this literature review, we briefly review the candidate genes that have been implicated in the development and severity of the PTSD phenotype. Read More

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http://dx.doi.org/10.3390/genes10020140DOI Listing
February 2019

Optimisation of Protein Extraction from Medicinal Cannabis Mature Buds for Bottom-Up Proteomics.

Molecules 2019 Feb 13;24(4). Epub 2019 Feb 13.

Agriculture Victoria Research, AgriBio, Centre for AgriBioscience, Bundoora, Victoria 3083, Australia.

Medicinal cannabis is used to relieve the symptoms of certain medical conditions, such as epilepsy. Cannabis is a controlled substance and until recently was illegal in many jurisdictions. Consequently, the study of this plant has been restricted. Read More

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http://dx.doi.org/10.3390/molecules24040659DOI Listing
February 2019

Effects of Winter Flounder Antifreeze Protein on the Growth of Ice Particles in an Ice Slurry Flow in Mini-Channels.

Biomolecules 2019 Feb 18;9(2). Epub 2019 Feb 18.

Faculty of Mechanical Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.

The control of ice growth in ice slurry is important for many fields, including (a) the cooling of the brain during cardiac arrest, (b) the storage and transportation of fresh fish and fruits, and (c) the development of distributed air-conditioning systems. One of the promising methods for the control is to use a substance such as antifreeze protein. We have observed and report here growth states of ice particles in both quiescent and flowing aqueous solutions of winter flounder antifreeze proteins in mini-channels with a microscope. Read More

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http://dx.doi.org/10.3390/biom9020070DOI Listing
February 2019