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Sci Rep 2021 May 4;11(1):9525. Epub 2021 May 4.

Universal Eye Center, Taipei, Taiwan, Republic of China.

Currently, there is no clear consensus in cataract surgery if low compared to high energy femto-lasers may enable better capsulotomy quality and induce lower inflammatory response. Therefore, the aim of this study was to compare the intra-operative outcomes achieved with high and low pulse energy femtosecond laser systems for cataract surgery. The charts of 200 eyes of 200 patients aged 68. Read More

Cardiol J 2021 ;28(2):351-352

Department of Cardiology, Geneva University Hospital, Geneva, Switzerland, Gabrielle- Perret-Gentil 4, 1205 Genève, Switzerland.

Ophthalmol Ther 2021 Jun 17;10(2):337-348. Epub 2021 Apr 17.

Department of Vitreoretinal Services, Disha Eye Hospitals, Kolkata, 700120, India.

Introduction: To assess the safety profile of the intravitreal ranibizumab biosimilar molecule, Razumab (Intas Pharmaceuticals, Ahmedabad, India) in chorioretinal disorders under real-world conditions.

Methods: This was a multicenter, retrospective chart review which included patients from 15 centers receiving intravitreal Razumab (IVRz) injections from 2016 to 2020. Patient demographics, ocular examination data, and detailed safety information regarding serious adverse events (SAE) or serious adverse drug reactions (sADR), and non-serious AEs (nsAE) or non-serious ADRs (nsADR) occurring within 1 month of IVRz injections were compiled. Read More

Int Med Case Rep J 2021 7;14:219-222. Epub 2021 Apr 7.

Department of Ophthalmology, Tabuk University, Tabuk, Saudi Arabia.

Purpose: To report the poor visual outcome of ruptured globe caused by camel bites.

Observations: A 48-year-old camel caregiver presented to the emergency department after being bitten by a camel in the left side of his face. Ophthalmic examination revealed a superior scleral wound from 9 to 2 o'clock, about 6 mm from the limbus extending to the equator with prolapse of uveal and vitreous tissues, an opaque cornea, total hyphema, diffuse subconjunctival hemorrhage, and a lower lid laceration involving the lid margin and the nasolacrimal duct. Read More

Arq Bras Oftalmol 2021 Mar-Apr;84(2):183-185

Department of Dermatomology, Istanbul Medeniyet University School of Medicine, Goztepe, Kadikoy, Istanbul, Turkey.

A 62-year-old woman was admitted to our clinic with the complaints of periorbital ecchymosis and subconjunctival hemorrhage that are visible, especially on the right eye. We noted that her complaints began the day after she underwent leech therapy on the glabella area for headache. On the glabella, 2 leech bites were observed close to the right side. Read More

Clin Case Rep 2021 Mar 19;9(3):1235-1240. Epub 2021 Jan 19.

Lorrainevet Ludres France.

A 5-year-old Doberman Pinscher dog was presented with sudden onset left-sided periocular bleeding following third eyelid gland replacement surgery. Left-sided exophthalmos and 360-degrees subconjunctival hemorrhage were present. The ophthalmic examination revealed blindness with absent direct and consensual pupillary light reflexes. Read More

Am J Ophthalmol Case Rep 2021 Jun 26;22:101049. Epub 2021 Feb 26.

Department of Ophthalmology, University of Cincinnati, 3230 Eden Ave, Cincinnati, OH, 45267, USA.

Purpose: To describe a case of massive spontaneous subconjunctival hemorrhage in a patient taking warfarin with a therapeutic international normalized ratio (INR).

Observations: Massive circumferential hemorrhagic chemosis, extensive periorbital and facial ecchymosis, and active arterial extravasation in the subconjunctiva which required cessation and reversal of anticoagulation. Findings gradually resolved over several months after discharge. Read More

Indian J Ophthalmol 2021 Apr;69(4):900-905

Department of Ophthalmology, Army Hospital (Research and Referral), New Delhi, India.

Purpose: The aim of this study was to report the ocular findings in renal allograft recipients in India.

Methods: A cross-sectional, comprehensive ophthalmic evaluation was performed, at least three months postrenal transplant, in 152 renal allograft recipients for the ocular findings. In addition, ocular findings were assessed for an association with the clinical variables like major etiologies of end-stage renal disease, pre-transplant dialysis duration, post-transplant duration, and dosage of immunosuppressive drugs. Read More

Vestn Otorinolaringol 2021 ;86(1):112-116

Research Institute of Eye Diseases, Moscow, Russia.

Recently, an increase in the number of operations on the lacrimal ducts performed by otorhinolaryngologists has been noted throughout the world. During these operations, intra- and postoperative complications may develop, which require the intervention of an ophthalmologist. A rare complication of endoscopic dacryocystorhinostomy is the development of retrobulbar hemorrhage. Read More

Int Med Case Rep J 2021 3;14:139-144. Epub 2021 Mar 3.

Ophthalmology Unit, Department of Surgery, Abia State University Teaching Hospital, Aba, Abia State, Nigeria.

Introduction: Chronic renal failure (CRF) is a multi-systemic disease affecting different organ systems of the body. Ocular manifestations of chronic renal disease include squint, subconjunctival hemorrhage, vitreous hemorrhage, neovascular glaucoma, cataracts and retinal detachment. These result in visual impairment or blindness. Read More

J Ocul Pharmacol Ther 2021 May 8;37(4):230-235. Epub 2021 Mar 8.

Ophthalmology Department, Konyagoz Eye Hospital, Konya, Turkey.

In this study, we wanted to retrospectively evaluate the effect of the use of topical brimonidine on intraoperative bleeding and surgical hemostasis before strabismus surgery. Brimonidine tartrate 0.15% (Brimogut, Bilim Ilac, Turkey) eye drops were applied 6 and 3 min before surgery to 44 eyes of 22 patients in group 1 for vasoconstriction. Read More

Vision (Basel) 2021 Feb 21;5(1). Epub 2021 Feb 21.

Department of Ophthalmology, University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester LE1 5WW, UK.

Purpose: To describe an atypical case of sympathetic ophthalmia presenting after blunt trauma causing disinsertion of the iris in an intact globe.

Methods: Case report.

Results: A 71-year-old lady presented to the Emergency Department following a mechanical fall. Read More

Anasthesiol Intensivmed Notfallmed Schmerzther 2021 Feb 19;56(2):135-140. Epub 2021 Feb 19.

Roll-over trauma and associated traumatic entrapments frequently result in serious polytraumatisation. In rare cases, severe extrathoracic compressions and a protracted entrapment period can lead to Perthes syndrome, also known as traumatic asphyxia. The Perthes syndrome manifests itself by a triad of craniocervical cyanosis, facial petechiae and subconjunctival haemorrhages, enabling a rapid diagnosis based on these typical clinical features. Read More

Zhonghua Yan Ke Za Zhi 2021 Feb;57(2):139-141

Beijing Aier Intech Eye Hospital, Aier Corneal Institute, Beijing 100021, ChinaCorresponding auther: Sun Xuguang, Email:

A 34-year-old female presented to the doctor with chief complaint of redness in both eyes for 1 week. The slit lamp examination showed slight eyelid swelling, water-like discharge in the conjunctival sac of the lower eyelid, conjunctival follicles, gray-white pseudomembrane and small lamellar subconjunctival hemorrhage on the lower palpebral conjunctiva. Physical examination showed two erythematous macules(size 5 mm×6 mm) on the left palm. Read More

Cureus 2020 Dec 17;12(12):e12125. Epub 2020 Dec 17.

Ophthalmology, University of Florida, Gainesville, USA.

Snake bites involving the eye are an uncommon cause of ocular trauma; herein, we present one of the few known instances of a snake bite directly to the globe, specifically by the way of a , also known as the "Black Racer." In this case report, we describe a nine-year-old girl who presented immediately following a snake bite to the right eye. The patient's vision was unaffected despite visualized puncture wounds through the conjunctiva with associated near-total subconjunctival hemorrhage. Read More

Clin Ophthalmol 2021 15;15:183-188. Epub 2021 Jan 15.

Department of Ophthalmology, Shri Vasantrao Naik Government Medical College, Yavatmal 4510001, Maharashtra, India.

Purpose: To determine the incidence of non-traumatic subconjunctival hemorrhage (NTSH) in Indian rural population and analyze the associated risk factors.

Methods: The study included patients diagnosed having subconjunctival hemorrhage (SCH) who attended the out-patient department (OPD) of ophthalmology. Demographic characteristics of subjects included age, gender, medical and ocular history, and location of hemorrhage. Read More

J Ophthalmol 2020 30;2020:4310258. Epub 2020 Nov 30.

Department of Ophthalmology, Peking University Third Hospital, Beijing, China.

Background: Bleb needling with subconjunctival injection of antimetabolites had become a widely accepted approach for trabeculectomy failure. However, IOP reduction effects, success rates, and complications occurrence for this procedure showed great inconsistency among the different studies.

Methods: We conducted a literature search on PubMed, Embase, Cochrane Library, and ClinicalTrials. Read More

Indian J Ophthalmol 2021 01;69(1):66-68

Chairman, The Eye Foundation, Coimbatore, Tamil Nadu, India.

Purpose: To compare horizontal and vertical split conjunctival autograft technique in the management of double head pterygium.

Methods: Retrospective analysis of 96 and 99 eyes with double head pterygia that underwent horizontal (Group 1) and vertical (Group 2) split conjunctival autografting, respectively. Comparison of recurrence rates and other complications was done. Read More

Curr Opin Ophthalmol 2021 Mar;32(2):160-168

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.

Purpose Of Review: This article reviews the safety profile of trabecular meshwork/Schlemm's canal-based, subconjunctival, and suprachoroidal minimally invasive glaucoma surgery (MIGS).

Recent Findings: Prospective randomized clinical trials and metaanalyses published during the 2019-2020 review period provided important data regarding the safety profile of trabecular meshwork/Schlemm's canal-based MIGS. Transient hyphema and intraocular pressure spikes are among the most common complications associated with this category of MIGS, but more serious adverse events such as cyclodialysis cleft formation may also occur. Read More

Cureus 2020 Oct 31;12(10):e11273. Epub 2020 Oct 31.

Ophthalmology, 12 de Octubre Hospital, Complutense University, Madrid, ESP.

A non-traumatic or spontaneous orbital hemorrhage (NTOH) is usually caused by the presence of an orbital mass, an inflammation, an infection, a bleeding disorder or those called idiopathic. This entity usually affects elderly adults and some risk factors can be identified. The NTOH normally acts like a benign and self-limited process, but attending to its anatomical pattern, may need specific management. Read More

Jpn J Ophthalmol 2021 Jan 26;65(1):107-114. Epub 2020 Nov 26.

Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Yonago-city, Tottori, 683-8504, Japan.

Purpose: The aim of this study was to compare the efficacy of the topical regimens of iodine/steroids vs. antibiotics/steroids in acute to subacute adenoviral keratoconjunctivitis.

Study Design: A prospective open-label study. Read More

JAMA Ophthalmol 2021 01;139(1):125-126

John A. Moran Eye Center, The University of Utah, Salt Lake City.

Clin Ophthalmol 2020 12;14:3211-3218. Epub 2020 Oct 12.

Department of Ophthalmology, HanGil Eye Hospital, Incheon, Korea.

Purpose: To evaluate the short-term ophthalmic side effects of bilateral same-day intravitreal anti-vascular endothelial growth factor (VEGF) injections.

Patients And Methods: We retrospectively analyzed patients who received intravitreal bevacizumab, ranibizumab, and aflibercept injections in both eyes on the same day between January 2014 and June 2019. The patients were followed up for 1 day, 1 week, and 1 month after the injections. Read More

J Maxillofac Oral Surg 2020 Dec 23;19(4):585-590. Epub 2019 Oct 23.

Ophthalmology Department, Obafemi Awolowo University Teaching Hospitals Complex, Ife, Osun Nigeria.

Objectives: The study investigated the association between intraocular pressure changes and clinical ocular signs in 51 patients with orbitozygomatic complex fractures. Diplopia, chemosis, enophthalmos, subconjunctival haemorrhage, periorbital ecchymosis and extraocular muscles entrapment were assessed.

Study Design: Intraocular pressure was measured in mmHg at different time intervals with Perkins and Goldman tonometers; within first 3 days of injury (T1), 24 h post-elevation within 3-14 days of injury (T2), 1 month after initial treatment assessment (T3), 2 months after initial treatment assessment (T4), and 3 months after initial treatment assessment (T5). Read More

Int Ophthalmol 2021 Feb 18;41(2):549-558. Epub 2020 Oct 18.

Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Meishan Road, Shushan District, Hefei, 230022, Anhui Province, China.

Background: Cyclocryotherapy and transscleral cyclophotocoagulation are commonly used procedures for the treatment of refractory glaucoma, but still with many complications. Ultrasound cyclo plasty (UCP) is a novel technique that determines a selective and more precise coagulation necrosis of the ciliary body to reduce intraocular pressure (IOP), but its efficacy and safety have been less investigated in Chinese population. This study aimed to evaluate the clinical efficacy and safety of UCP in Chinese patients with refractory glaucoma. Read More

Clin Ophthalmol 2020 24;14:2837-2842. Epub 2020 Sep 24.

Department of Ophthalmology, Loma Linda University Eye Institute, Loma Linda, CA, USA.

Purpose: The purpose of this study was to determine the incidence of minor and major ocular injuries in patients with orbital wall fractures at Loma Linda University Health, a level-one trauma center, to help determine the most appropriate setting for the initial dilated fundus examination by ophthalmologists.

Methods: A retrospective study was performed from January 2008 to January 2013 of patients diagnosed with orbital wall fracture secondary to trauma. Exclusion criteria included unknown mechanism of injury, the absence of ophthalmology consultation, or absence of imaging. Read More

Ophthalmol Retina 2020 Oct 12. Epub 2020 Oct 12.

Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

Purpose: The intravitreal injection (IVI) of pharmacologic agents is the most commonly performed ocular procedure and is associated with a host of complications. Most IVI-related complications data are derived from randomized controlled clinical trials, which report a high adverse event rate. The nature of these protocol-driven trials limit their applicability to the diverse circumstances seen in routine clinical practice. Read More

Eye (Lond) 2020 Oct 1. Epub 2020 Oct 1.

Department of Anaesthesia, Khoo Teck Puat Hospital, Yishun Central 90, Singapore, Singapore.

Background/objectives: Standard sub-Tenon's block (STB) involves incision (dissection) of conjunctiva and Tenon's capsule with the help of blunt scissors and forceps, insertion of a blunt sub-Tenon's cannula under the Tenon's capsule and injection of local anaesthetic agent. STB is frequently associated with minor complications such as chemosis and postoperative subconjunctival haemorrhage but rare sight and life-threatening complications. To reduce these minor complications, several variations of incisionless STB have been described however, there are no comparative data. Read More

Case Rep Ophthalmol 2020 May-Aug;11(2):473-480. Epub 2020 Aug 11.

Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Retinal vascular occlusion after ocular surgery is a rare but serious complication. A history of cardiovascular diseases, retrobulbar anesthesia injection, high intraocular pressure during the perioperative period, and drug toxicity have been reported as possible causative factors. We report here two cases of multiple retinal vascular occlusions after the subconjunctival injection of gentamicin at the end of uncomplicated 25-gauge vitrectomy. Read More

Cornea 2020 Dec;39(12):1588-1591

The S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russian Federation; and.

Purpose: To assess the anatomic and visual results of the modified glueless simple limbal epithelial transplantation (G-SLET) in the treatment of unilateral limbal stem cell deficiency (LSCD).

Methods: This is a retrospective analysis of 2 patients who received G-SLET for corneal reepithelization after unilateral eye burn. After the recipient bed preparation on the eye with LSCD, radial symmetrical superficial incisions were applied to the corneal periphery. Read More