209 results match your criteria Subchorionic Hemorrhage


Prenatal diagnosis of multiple large subchorionic placental cysts with intracystic hemorraghe.

Facts Views Vis Obgyn 2017 Dec;9(4):223-225

Department of Pathology, Ziekenhuis Oost-Limburg, Genk (ZOL), Genk, Belgium.

Subchorionic placental cysts occur in up to 5% of pregnancies. Large and numerous placental cysts increase the risk for intrauterine growth restriction. We describe a case with large multiple subchorionic placental cysts complicated by intracystic hemorraghe and fetal growth restriction. Read More

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December 2017

Placental abruption and hemorrhage-review of imaging appearance.

Emerg Radiol 2018 Aug 29. Epub 2018 Aug 29.

Department of Radiology, University of Washington Medical Center, 1959 NE pacific St., Seattle, WA, 98195, USA.

Placental and periplacental bleeding are common etiologies for antepartum bleeding. Placental abruption complicates approximately 1% of pregnancies and is associated with increased maternal, fetal, and neonatal morbidity and mortality. This article reviews the normal placental appearance on ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) and then discusses the different morphological appearance of placental and periplacental hematomas along with their mimics. Read More

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August 2018
8 Reads

The presence of amniotic fluid sludge in pregnant women with a short cervix: an independent risk of preterm delivery.

J Matern Fetal Neonatal Med 2018 Sep 19:1-4. Epub 2018 Sep 19.

b Department of Obstetrics and Gynecology , Nippon Medical School Hospital , Tokyo , Japan.

Objective: To examine whether the presence of amniotic fluid sludge (AFS) could increase the risk of preterm delivery in women with a cervical length (CL) of less than 25 mm.

Materials And Methods: This is a retrospective cohort study of 110 women who were 14-30 weeks pregnant with a singleton gestation and a CL of less than 25 mm. The primary outcomes were defined as preterm delivery before 34 weeks and preterm delivery before 37 weeks. Read More

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September 2018

Large Subchorionic Hematoma: Breus' Mole.

J Med Ultrasound 2017 Oct-Dec;25(4):248-250. Epub 2017 Nov 27.

Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Egypt.

A case of large subchorionic hematoma complicated by intrauterine growth retardation and oligohydramnios diagnosed at 32 weeks' gestation with twin pregnancy after ICSI is reported below. The patient was on clexane injection during pregnancy for mitral valve replacement. She was managed with tocolysis using progesterone therapy and antibiotic with fol-lowup until delivery. Read More

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November 2017

Alpha lipoic acid in obstetrics and gynecology.

Gynecol Endocrinol 2018 Sep 4;34(9):729-733. Epub 2018 May 4.

a Department of Gynecological, Obstetrical and Urological Sciences , ''Sapienza'' University of Rome , Rome , Italy.

Alpha-Lipoic acid (ALA) is a natural antioxidant synthetized by plants and animals, identified as a catalytic agent for oxidative decarboxylation of pyruvate and α-ketoglutarate. In this review, we analyzed the action of ALA in gynecology and obstetrics focusing in particular on neuropathic pain and antioxidant and anti-inflammatory action. A comprehensive literature search was performed in PubMed and Cochrane Library for retrieving articles in English language on the antioxidant and anti-inflammatory effects of ALA in gynecological and obstetrical conditions. Read More

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September 2018
1 Read
1.140 Impact Factor

Thrombin Alters Human Endometrial Stromal Cell Differentiation During Decidualization.

Reprod Sci 2018 Jan 1:1933719118768705. Epub 2018 Jan 1.

1 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Vaginal bleeding and subchorionic hematomas are associated with increased risk of both early and late pregnancy loss. Thrombin generation may play a pivotal role in the development of these complications. To determine the effects of thrombin on human endometrial stromal cells (hESCs), cells were treated with thrombin at baseline or during decidualization with cyclic adenosine monophosphate (cAMP)+medroxyprogesterone acetate (MPA). Read More

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January 2018

Effectiveness and safety of sublingual misoprostol in medical treatment of the 1st trimester miscarriage: experience of off-label use in Korea.

Obstet Gynecol Sci 2018 Mar 2;61(2):220-226. Epub 2018 Mar 2.

Department of Obstetrics and Gynecology, Seoul Metropolitan-Government Seoul National University Boramae Medical Center, Seoul, Korea.

Objective: This study was conducted to determine the effectiveness and safety of medical treatment with sublingual misoprostol (MS) in the 1st trimester miscarriage under the approval by Health Insurance Review and Assessment Service (HIRA) for off-label usage by the single medical center in Korea.

Methods: A retrospective cohort study was performed in one institution between April 2013 and June 2016. Ninety-one patients diagnosed with miscarriage before 14 weeks of gestation and wanted to try medical treatment were included. Read More

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March 2018
1 Read

Unique fluid-fluid level ultrasonic appearance in subacute placenta abruption with massive subchorionic hematoma.

Int J Gynaecol Obstet 2018 06 13;141(3):391-392. Epub 2018 Mar 13.

Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

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June 2018
5 Reads

A large subchorionic placental cyst with thalassemia minor without fetal growth restriction.

Taiwan J Obstet Gynecol 2018 Feb;57(1):161-162

Department of Pathology, Kuang Tien General Hospital, Shalu, Taichung, Taiwan.

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February 2018
2 Reads

Subchorionic Hematoma: Correlation of Grading Techniques With First-Trimester Pregnancy Outcome.

J Ultrasound Med 2018 Jul 17;37(7):1725-1732. Epub 2018 Jan 17.

Departments of Radiology, Obstetrics and Gynecology , Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Objectives: To evaluate and compare grading systems of subchorionic hematoma (SCH) on first-trimester ultrasound examinations with live embryos to assess which best correlates with early pregnancy outcome and to assess the effect of gestational age at the time of diagnosis on outcome.

Methods: First-trimester live singleton pregnancies between 6 and 11 weeks' gestational age with SCH were identified by an institutional database search. First-trimester outcome was categorized as "live" or "demise" based on ultrasound or medical record documentation. Read More

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July 2018
1 Read

Placental Pathologic Associations With Morbidly Adherent Placenta: Potential Insights Into Pathogenesis.

Pediatr Dev Pathol 2017 Sep-Oct;20(5):387-393. Epub 2017 Mar 20.

2 Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Background The pathology that underlies morbidly adherent placenta (MAP) is poorly understood. The objective of this study was to describe the placental pathology, especially implantation site pathology, associated with MAP. Methods This was a single institution, retrospective case-control study design examining placentas of patients who delivered between January 2008 and September 2013. Read More

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March 2017
21 Reads

Outcomes of threatened abortions after anticoagulation treatment to prevent recurrent pregnancy loss.

Reprod Biomed Online 2017 Oct 3;35(4):461-467. Epub 2017 Jul 3.

Department of Hematology, Hadassah-Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel. Electronic address:

We aimed to determine the outcome of threatened abortion in women treated with low-molecular weight heparin (LMWH) for recurrent pregnancy loss (RPL). Data of women with RPL who experienced threatened abortion while taking LMWH between 2007 and 2016 were retrospectively reviewed. All patients received the LMWH, enoxaparin (40 mg). Read More

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October 2017
18 Reads

Placental mesenchymal dysplasia: What every radiologist needs to know.

Indian J Radiol Imaging 2017 Jan-Mar;27(1):62-64

Department of Radiodiagnosis, Lady Hardinge Medical College, New Delhi, India.

Placental mesenchymal dysplasia (PMD) is an uncommon vascular anomaly of the placenta characterized by placentomegaly with multicystic placental lesion on ultrasonography and mesenchymal stem villous hyperplasia on histopathology. Placental mesenchymal dysplasia should be considered in the differential diagnosis of cases of multicystic placental lesion such as molar pregnancy, chorioangioma, subchorionic hematoma, and spontaneous abortion with hydropic placental changes. However, lack of high-velocity signals inside the lesion and a normal karyotype favor a diagnosis of PMD. Read More

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May 2017
25 Reads

The predictive role of sTWEAK levels in pregnant women with first-trimester vaginal bleeding.

J Matern Fetal Neonatal Med 2018 Jul 19;31(13):1715-1719. Epub 2017 May 19.

d Department of Obstetrics and Gynecology , İzmir Tepecik Training and Research Hospital , İzmir , Turkey.

Purpose: To investigate the relationships of TNF-related weak inducer of apoptosis (sTWEAK), a cytokine related to the TNF superfamily, its newly described soluble receptor sCD163, and the sTWEAK/sCD163 ratio with perinatal outcomes in women with first-trimester vaginal bleeding.

Materials And Methods: Seventy (41 threatened abortion and 29 control) gestational-age-matched (6-14 weeks) pregnant women were included in the study. Antenatal complications (gestational diabetes, preeclampsia, intrauterine growth restriction, oligohydramniosis, polyhydramniosis), and perinatal outcomes (delivery mode, birth weight, delivery week) were recorded. Read More

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July 2018
15 Reads

Prior uterine bleeding is associated with low visibility due to discolored amniotic fluid on fetoscopic laser photocoagulation.

J Obstet Gynaecol Res 2016 Dec 20;42(12):1652-1656. Epub 2016 Sep 20.

Department of Obstetrics, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.

Aim: To investigate the association between uterine bleeding preceding fetoscopic laser photocoagulation (FLP) and the presence of discolored amniotic fluid that impedes FLP.

Methods: A retrospective review of all multiple gestations requiring FLP at the present institution was conducted. The rate of low visibility because of discolored amniotic fluid at the beginning of FLP was compared between patients with and without a history of uterine bleeding, defined as either genital bleeding or ultrasonographically detected subchorionic hematoma. Read More

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December 2016
7 Reads

Prenatal Diagnosis of Twin Pregnancies with Complete Hydatidiform Mole and Coexistent Normal Fetus: A Series of 13 Cases.

Gynecol Obstet Invest 2017 13;82(4):404-409. Epub 2016 Aug 13.

Department of Obstetrics and Gynecology, San Raffaele Scientific Institute, Milan, Italy.

Aim: The study aimed to describe prenatal diagnosis and the outcome of complete hydatidiform mole and coexistent normal fetus (CHMCF).

Methods: This was a retrospective case series of 13 patients with CHMCF. Prenatal diagnosis, outcome and development of gestational trophoblastic neoplasia (GTN) were reviewed. Read More

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June 2018
7 Reads

Velamentous insertion of umbilical cord with vasa praevia: case series and literature review.

J Med Life 2016 Apr-Jun;9(2):126-9

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; "Sf. Pantelimon" Clinical Emergency Hospital, Bucharest, Romania.

A velamentous umbilical cord is characterized by membranous umbilical vessels at the placental insertion site that are prone to compression and rupture, especially when they are located in the membranes covering the cervical os (vasa praevia). The velamentous insertion of the umbilical cord, with a reported incidence of 1% in singleton pregnancies and 15% in monochorionic twin gestations, has been associated with obstetric complications: fetal growth restriction, prematurity, congenital anomalies, low Apgar scores, fetal bleeding with acute fetal distress and placental retention. The pathogenesis is unknown, but the trophotropism theory is the most common and supported by the association of velamentous cord insertion and placenta praevia. Read More

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April 2017
7 Reads

Placental Pathologic Associations with Morbidly Adherent Placenta: Potential insights into Pathogenesis.

Pediatr Dev Pathol 2016 Jul 21. Epub 2016 Jul 21.

4 Northwestern University.

Background: The pathology that underlies morbidly adherent placenta (MAP) is poorly understood. The objective of this study was to describe the placental pathology, especially implantation site pathology, associated with MAP.

Methods: This was a single institution, retrospective case-control study design examining placentas of patients who delivered between January 2008 and September 2013. Read More

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July 2016
8 Reads

Immunomodulatory activities of alpha lipoic acid with a special focus on its efficacy in preventing miscarriage.

Expert Opin Drug Deliv 2016 Dec 24;13(12):1695-1708. Epub 2016 Jun 24.

e Department of Medical Sciences , UNIIPUS - Private Swiss University Institute , Chiasso , Switzerland.

Introduction: Alpha lipoic acid (ALA) is an essential mitochondrial co-factor and, as a free molecule, it can exert multi-level immunomodulatory functions. Both ALA and its reduced form, dihydrolipoic acid (DHLA), are believed to be able to chelate heavy metals, to regenerate essential antioxidants and to repair important molecules damaged by oxidation. The largest part of the effects of ALA/DHLA couple can be explained by a specific stimulatory activity on Nrf2-dependent gene transcription and by the inhibition of NF-kB activity. Read More

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December 2016
7 Reads

Anemia in a neonate with placental mesenchymal dysplasia.

Clin Case Rep 2016 May 22;4(5):463-5. Epub 2016 Mar 22.

Department of Obstetrics Hokkaido University Graduate School of Medicine Sapporo Japan.

Causes of intrauterine fetal death (IUFD) are uncertain in most placental mesenchymal dysplasia (PMD) cases. Our case showed high α-fetoprotein levels in the maternal circulation, markedly dilated subchorionic vessels, and neonatal hemoglobin concentration of 8.4 g/dL, suggesting that fetal anemia may explain some adverse outcomes in PMD pregnancies. Read More

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May 2016
11 Reads

[Effects of subchorionic hematoma on pregnancy outcome: a meta analysis].

Zhonghua Yi Xue Za Zhi 2016 May;96(17):1383-5

Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200090, China.

Objective: To study the effects of subchorionic hematoma (SCH) on pregnancy outcome.

Methods: We searched publications from January 2000 to July 2015 for cohort and case-control studies evaluating subchorionic hematoma and perinatal outcomes, including spontaneous abortion, premature delivery and delivery mode.

Results: Data of 6 articles analyzed by meta-analysis showed that SCH group had higher rate of spontaneous abortion, while no difference in premature delivery and delivery mode, compared with threatened abortion group. Read More

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May 2016
25 Reads

Resolution of subchorionic hematoma and symptoms of threatened miscarriage using vaginal alpha lipoic acid or progesterone: clinical evidences.

Eur Rev Med Pharmacol Sci 2016 04;20(8):1656-63

Department of Chemistry and Pharmaceutical Technologies, University of Ferrara, Ferrara, Italy.

Objective: Alpha Lipoic Acid (ALA) is a safe natural molecule that exerts a selective immunomodulating activity with antioxidant and anti-inflammatory properties. This randomized controlled clinical trial (RCT) tested the effect of the vaginal administration with ALA or Progesterone, in subchorionic hematoma resorption in women with threatened miscarriage.

Patients And Methods: 400 mg of vaginal Progesterone or 10 mg of vaginal ALA were administered to sixty-two pregnant women, in the first trimester of gestation with threatened miscarriage and subchorionic hematoma. Read More

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April 2016
16 Reads

Hepatocellular Adenoma of the Placenta With Updated Immunohistochemical and Molecular Markers: A Case Report.

Int J Surg Pathol 2016 Oct 22;24(7):640-3. Epub 2016 Apr 22.

Beth Israel Deaconess Medical Center, Boston, MA, USA

We describe the clinicopathological, immunohistochemical, and molecular features of an unusual case of a hepatocellular adenoma of the placenta presenting as a subchorionic intervillous mass lesion in a diamnionic dichorionic placenta. A well-circumscribed 0.8 cm round nodule was identified in one of the twin placental discs, wherein, on microscopic review, the lesional cells morphologically and immunophenotypically resembled fetal hepatocytes. Read More

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October 2016
3 Reads

First-trimester bleeding and twin pregnancy outcomes after in vitro fertilization.

Fertil Steril 2016 07 7;106(1):140-143. Epub 2016 Apr 7.

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Objective: To examine the association between first-trimester bleeding and live-birth rates in twin pregnancies conceived with in vitro fertilization (IVF).

Design: Retrospective cohort study.

Setting: Academic infertility practice. Read More

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July 2016
6 Reads

Nrf2 Activation Inhibits Effects of Thrombin in Human Amnion Cells and Thrombin-Induced Preterm Birth in Mice.

J Clin Endocrinol Metab 2016 06 6;101(6):2612-21. Epub 2016 Apr 6.

The Cecil H. and Ida Green Center for Reproductive Biology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9032.

Context: Nrf2 is a key transcription factor that modulates cell defense mechanisms against endogenous and exogenous stress. Previously, we reported that thrombin increased matrix metalloproteinases and prostaglandin synthesis in human amnion mesenchymal cells.

Objective: We sought to determine whether activation of Nrf2 alters the effect of thrombin on prostaglandin synthesis, protease activation, and cytokine release in human amnion. Read More

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June 2016
13 Reads

The effect of first trimester subchorionic hematoma on pregnancy outcomes in patients underwent IVF/ICSI treatment.

J Matern Fetal Neonatal Med 2017 Feb 28;30(4):406-410. Epub 2016 Apr 28.

a Reproductive Medicine Center, Department of Obstetrics and Gynecology, Drum Tower Hospital Affiliated to Nanjing University Medical College , Nanjing , Jiangsu , PR China.

Objective: The aim of this retrospective cohort study was to assess the effect of subchorionic hematoma (SCH) on pregnancy outcomes in IVF/ICSI patients.

Methods: We retrospectively analyzed 1097 pregnancies achieved by in vitro fertilization and embryo transfer (IVF-ET) or frozen-thawed embryo transfers (FETs) between January 2013 and June 2013 at the IVF center of Nanjing Drum Tower Hospital. The prevalence of SCH was 12. Read More

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February 2017
26 Reads

A Rare Cause of Placental Abruption: Uterine Torsion.

J Clin Diagn Res 2016 Jan 1;10(1):QD06-7. Epub 2016 Jan 1.

Faculty, Department of Obstetrics and Gynecology, Ümraniye Medical and Research Hospital , Istanbul, Turkey .

Uterine torsion is defined as a rotation on its long axis and it is a dangerous, unexpected obstetric emergency. We report a case of uterine torsion at 32 weeks of gestation in a singleton pregnancy. A 37-year-old woman with multiple prior cesarean deliveries referred to emergency unit of our hospital at 32 weeks of gestation with severe abdominal pain and mild vaginal bleeding. Read More

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January 2016
1 Read

Funisitis is associated with adverse neonatal outcome in low-risk unselected deliveries at or near term.

Virchows Arch 2016 Apr 11;468(4):503-7. Epub 2016 Feb 11.

Departments of Paediatric Pathology, Camelia Botnar Laboratories, Great Ormond Street Hospital and Institute of Child Health, Great Ormond Street, London, WC1N 3JH, UK.

This study aimed to determine the incidence and clinical outcomes for varying patterns of placental histological inflammation (consistent with fetal or maternal inflammatory response) in an unselected population of >1000 women with a singleton pregnancy resulting in live birth delivering at or near term. One thousand one hundred nineteen cases were studied in a blind, prospective, unselected study with placentas categorized into five histological subgroups reflecting underlying maternal or fetal inflammatory response. Clinical outcomes studied included interventional delivery, an Apgar score <7 at 1 min, neonatal acidosis (pH < 7. Read More

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[Dysfibrinogenemia developed in a pregnant woman who has fibrinogen AαThr312Ala (ACT/GCT) polymorphism].

Rinsho Ketsueki 2016 Jan;57(1):31-5

Department of Obstetrics and Gynecology, Japan Baptist Hospital.

Blood coagulation factors play an essential role in pregnancy. We describe a 30-year-old pregnant woman whose course was complicated by dysfibrinogenemia with polymorphism of fibrinogen AαThr312Ala (rs6050) GG genotype. She was admitted to our hospital for genital bleeding and a huge subchorionic hematoma at 6 gestational weeks. Read More

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January 2016
33 Reads

Subchorionic hematomas are increased in early pregnancy in women taking low-dose aspirin.

Fertil Steril 2016 05 25;105(5):1241-1246. Epub 2016 Jan 25.

Department of Obstetrics and Gynecology, Fertility Associates of Memphis, Vanderbilt University, Memphis, Tennessee.

Objective: To determine the frequency of subchorionic hematomas (SCH) in first-trimester ultrasound examinations of patients with infertility and recurrent pregnancy loss (RPL) and in patients from a general obstetric population. To determine if the method of assisted reproduction utilized or the use of anticoagulants, such as heparin and aspirin (ASA), influenced frequency of SCH.

Design: Prospective, cohort study. Read More

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May 2016
35 Reads

Massive Subchorionic Placental Cyst and Poor Fetal Growth: A Case Report.

J Reprod Med 2015 Sep-Oct;60(9-10):458-60

Background: Large placental cysts are unusual and rarely have significant impact on pregnancy.

Case: We present a case of a progressively enlarging placental cyst, to 13 cm, which ultimately led to delivery due to suboptimal fetal growth and umbilical cord entrapment against the uterine wall. Review of the literature, including inconsistent nomenclature and pathologic findings, will be discussed. Read More

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December 2015
1 Read

A 10-year restrospective evaluation of ultrasound in pregnant abdominal trauma patients.

Emerg Radiol 2016 Apr 19;23(2):105-9. Epub 2015 Nov 19.

Department of Radiology, University of California, San Diego Medical Center, 200 West Arbor Drive, San Diego, CA, 92103, USA.

The pregnant abdominal trauma patient presents a unique diagnostic challenge. This study aimed to evaluate the accuracy of abdominal sonography for the detection of clinically important injuries in pregnant abdominal trauma patients. A retrospective review was performed of a trauma center database from 2001 to 2011. Read More

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April 2016
3 Reads

Alpha Lipoic Acid (ALA) effects on subchorionic hematoma: preliminary clinical results.

Eur Rev Med Pharmacol Sci 2015 Sep;19(18):3426-32

Department of Obstetrics and Gynecology, University of Perugia, Perugia, Italy.

Objective: The clinic use of alpha Lipoic Acid (ALA) is linked to its capability to exert antioxidant effects and, more interestingly, to counteract the pathologic changes of complex networks of cytokines, chemokines and growth factors, restoring their physiological state. The aim of this randomized controlled clinical trial was to test the contribution of oral supplementation of ALA to the standard treatment with Progesterone vaginal suppositories, in healing subchorionic hematomas in patients with threatened miscarriage. Controls were administered only Progesterone suppositories. Read More

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September 2015
16 Reads

Placental Sonolucencies in the First Trimester: Incidence and Clinical Significance.

Ultrasound Q 2016 Mar;32(1):43-6

Departments of *Radiology and †Reproductive Medicine, University of California, San Diego, San Diego, CA; and ‡Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX.

Objectives: The aims of this study were to determine the incidence of placental sonolucencies on first-trimester screening sonograms in a general obstetric population and assess whether these findings are associated with adverse obstetric outcomes.

Methods: A retrospective cohort analysis of 201 pregnant patients screened at a high-risk prenatal diagnostic center was conducted with first-trimester cine clips reviewed by 2 radiologists. Placental sonolucencies were defined as intraplacental anechoic or heterogeneous areas 0. Read More

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March 2016
4 Reads

The relationship between first-trimester subchorionic hematoma, cervical length, and preterm birth.

Am J Obstet Gynecol 2015 Sep 14;213(3):403.e1-4. Epub 2015 May 14.

Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL.

Objective: The objective of the study was to evaluate the association between a sonographically diagnosed subchorionic hematoma (SCH) in the first trimester and subsequent midtrimester cervical length and preterm birth.

Study Design: In this cohort study, 512 women with an SCH on their first-trimester ultrasound were compared with 1024 women without a first-trimester SCH. All women underwent routine transvaginal cervical length measurement between 18 and 22 weeks. Read More

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September 2015
6 Reads

Can we measure the spiral and uterine artery blood flow by real-time sonography and Doppler indices to predict spontaneous miscarriage in a normal-risk population?

Australas J Ultrasound Med 2015 May 31;18(2):60-66. Epub 2015 Dec 31.

Obstetric Department Dr Sami Ulus Research and Training Hospital Ankara Turkey.

: The predictive value of spiral artery flow Doppler measurements of a subsequent early miscarriage in first trimester pregnancy is explored here. : The aim of this study is to determine uterine and spiral artery blood flow changes in first trimester subsequent miscarriages and correlate within the mechanisms of the Doppler indicies. : The uterine artery and spiral artery pulsatility and resistance indexes, systolic and diastolic ratios, acceleration times, and blood flow of both the right and left uterine arteries were obtained by trans vaginal color Doppler ultrasonography in consecutive viable pregnancies between 5 and 12 gestational week. Read More

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May 2015
1 Read

The effects of subchorionic hematoma on pregnancy outcome in patients with threatened abortion.

J Turk Ger Gynecol Assoc 2014 1;15(4):239-42. Epub 2014 Dec 1.

Department of Obstetrics and Gynaecology, Ankara University Faculty of Medicine, Ankara, Turkey.

Objective: To assess the effects of ultrasonographically detected subchorionic hematomas on pregnancy outcomes in patients with vaginal bleeding within the first half of pregnancy.

Material And Methods: Patients diagnosed with threatened abortion due to painless vaginal bleeding and who were followed up in an in-patient service during the first vaginal bleeding between January 2009 and December 2010 were included in this retrospective cohort study. Patients were divided into two groups according to the presence of subchorionic hematoma. Read More

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January 2015
6 Reads

Pearls and pitfalls in first-trimester obstetric sonography.

Clin Imaging 2015 Mar-Apr;39(2):176-85. Epub 2014 Oct 23.

Department of Radiology, Montefiore Medical Center, Albert Einstein College of Medicine.

Ultrasound is the primary imaging modality used in the evaluation of first-trimester vaginal bleeding and pelvic pain. This article will summarize the ultrasound findings in normal first-trimester pregnancy, failed pregnancy, ectopic pregnancy, subchorionic hemorrhage, retained products of conception, and gestational trophoblastic disease. Mastery of the spectrum of sonographic findings in the normal and abnormal first-trimester pregnancy allows the radiologist to make accurate diagnoses and helps to appropriately guide patient management. Read More

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October 2015
5 Reads

Symptoms of an intrauterine hematoma associated with pregnancy complications: a systematic review.

PLoS One 2014 4;9(11):e111676. Epub 2014 Nov 4.

Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, China.

Objective: To evaluate the predictive value of the symptoms of an intrauterine hematoma (IUH) for adverse pregnancy outcomes.

Methods: A literature review was performed with the search terms, including intrauterine/subchorionic/retroplacental/subplacental hematoma/hemorrhage/bleeding/collection/fluid, covering the period from January, 1981 to January, 2014. We just focused on the pregnancy outcomes associated with different symptoms of an IUH. Read More

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June 2015
11 Reads

Subchorionic hematoma occurs more frequently in in vitro fertilization pregnancy.

Eur J Obstet Gynecol Reprod Biol 2014 Oct 30;181:41-4. Epub 2014 Jul 30.

Department of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Nishihara, Okinawa, Japan.

Objective: Obstetric complications occur more frequently in pregnancies after in vitro fertilization (IVF). We attempted to determine the correlation between subchorionic hematoma and IVF pregnancies.

Study Design: We analyzed 194 pregnancies achieved by infertility treatment between January 2008 and February 2012 at our hospital. Read More

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October 2014
50 Reads

Placental pathologies on fetal MRI are associated with high impairment rates: a prospective long-term outcome study.

J Matern Fetal Neonatal Med 2015 Jul 14;28(10):1219-23. Epub 2014 Aug 14.

a Department of Pediatrics and Adolescent Medicine .

Objective: Placental anomalies visualized at midgestation by MRI are shown to be related to pregnancy outcome. We performed a prospective cohort study to investigate the influence of placental pathologies diagnosed with fetal MRI on long-term neurodevelopmental outcome.

Methods: In our hospital-based, cross-sectional study, all fetal MRI examinations of pregnancies with vascular placental pathology (i. Read More

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July 2015
9 Reads

[Prognostic significance of subchorionic hematoma for the course of pregnancy].

Ginekol Pol 2013 Nov;84(11):944-9

Klinika Medycyny Płodu i Ginekologii I Katedry Ginekologii i Połoznictwa Uniwersytetu Medycznego w Łodzi, Polska.

Objectives: the aim of this retrospective study was to assess if a first trimester subchorionic hematoma (SCH) influences the pregnancy outcome and whether pv bleeding can be a prognostic factor for the pregnancy course.

Material And Methods: the study included 185 pregnant women hospitalized due to symptoms of a threatening miscarriage. Patients were divided into 2 groups: 119 women with SCH (study group) and 66 patients with normal prenatal scan (control group), further subdivided into cases with and without pv bleeding, irrespectively of the outcome of the ultrasound scan. Read More

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November 2013
9 Reads

Uterine artery embolization of cervical varices before second-trimester abortion.

Obstet Gynecol 2014 Feb;123(2 Pt 2 Suppl 2):458-62

Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Background: Cervical varices are an extremely rare complication of pregnancy; they can result in significant maternal morbidity secondary to acute hemorrhage. There is limited evidence to guide the management of cervical varices during termination of pregnancy.

Case: A 37-year-old woman presented with recurrent vaginal hemorrhage at 17 weeks of gestation in the setting of a dichorionic-diamniotic twin gestation, an anterior placenta previa, a subchorionic hematoma visible on ultrasound examination, and prominent cervical varices. Read More

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February 2014
5 Reads

Endometriosis and pregnancy outcome: are pregnancies complicated by endometriosis a high-risk group?

Eur J Obstet Gynecol Reprod Biol 2014 Jan 31;172:36-9. Epub 2013 Oct 31.

Department of Obstetrics and Gynaecology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan.

Objectives: Increased incidence of preterm birth, pregnancy-induced hypertension (PIH) and small-for-gestational-age (SGA) babies have been reported in women with endometriosis, but the study populations included women in whom a definitive diagnosis was not attainable, and women who conceived via in vitro fertilization/embryo transfer (IVF/ET), which, in itself, is a risk factor for adverse pregnancy outcome. Thus there is a lack of consensus on the effects of endometriosis on pregnancy outcome. This study compared the pregnancy outcomes of women with or without a definitive diagnosis of endometriosis on laparoscopy. Read More

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January 2014
6 Reads

ACR appropriateness Criteria® second and third trimester bleeding.

Ultrasound Q 2013 Dec;29(4):293-301

*Baptist Hospital of Miami/South Miami Center for Women and Infants, Miami, Florida; †Walter Reed National Military Medical Center, Bethesda, Maryland; ‡Sunnybrook Health Sciences Centre, Bayview Campus, Toronto, Ontario, Canada; §University of Washington School of Medicine, Seattle, Washington; ∥Massachusetts General Hospital, Boston Massachusetts; ¶Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; #George Washington University Hospital, Washington, District of Columbia; **Thomas Jefferson University Hospital, Philadelphia, Pennsylvania; ††Massachusetts General Hospital, Boston Massachusetts; ‡‡Memorial Sloan Kettering Cancer Center, New York, New York; §§Brigham & Women's Hospital, Boston, Massachusetts, American College of Obstetrics and Gynecology; ∥∥Mallinckrodt Institute of Radiology, St. Louis, Missouri; ¶¶Columbia University, New York, New York, American College of Obstetrics and Gynecology; ##Mayo Clinic, Rochester, Minnesota; ***University of Maryland School of Medicine, Baltimore, Maryland; and †††Valley Hospital, Ridgewood, New Jersey, American College of Obstetrics and Gynecology.

Vaginal bleeding occurring in the second or third trimesters of pregnancy can variably affect perinatal outcome, depending on whether it is minor (i.e. a single, mild episode) or major (heavy bleeding or multiple episodes. Read More

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December 2013
6 Reads

Retrospective study of pregnant women placed under expectant management for persistent hemorrhage.

Arch Gynecol Obstet 2014 Feb 26;289(2):307-11. Epub 2013 Jul 26.

Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, 4-57 Urafunecyou, Minami-ku, Yokahama, Kanagawa, 232-0024, Japan,

Objective: To examine the clinicopathological characteristics of pregnant women who presented with intermittent hemorrhage occurring throughout pregnancy until delivery.

Method: A total of 24 women with intermittent hemorrhage occurring throughout pregnancy were categorized into two groups, a group with persistent subchorionic hematoma (PSH) and another with chronic abruption (CA), and the pregnancy outcomes were compared between the two groups. The data were expressed as medians (range). Read More

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February 2014
22 Reads

Patterns of placental pathology in preterm premature rupture of membranes.

J Dev Orig Health Dis 2013 Jun;4(3):249-55

3 Department of Obstetrics & Gynecology, University of Colorado Denver, Aurora, Colorado, USA.

Inflammation is associated with preterm premature rupture of membranes (PPROM) and adverse neonatal outcomes. Subchorionic thrombi, with or without inflammation, may also be a significant pathological finding in PPROM. Patterns of inflammation and thrombosis may give insight into mechanisms of adverse neonatal outcomes associated with PPROM. Read More

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Perioperative characteristics associated with preterm birth in twin-twin transfusion syndrome treated by laser surgery.

Am J Obstet Gynecol 2013 Sep 7;209(3):264.e1-8. Epub 2013 Jun 7.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Objective: To identify perioperative risk factors for preterm delivery (PTD) in laser-treated patients with twin-twin transfusion syndrome (TTTS).

Study Design: Twin-twin transfusion syndrome patients who underwent laser surgery were followed prospectively. Univariate and multivariate analyses were performed to identify gestational and surgical characteristics associated with preterm delivery. Read More

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September 2013
2 Reads

Prenatal diagnosis, clinical outcomes, and associated pathology in pregnancies complicated by massive subchorionic thrombohematoma (Breus' mole).

Prenat Diagn 2013 Oct 3;33(10):973-8. Epub 2013 Jul 3.

Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Ontario, Canada.

Objectives: To review the association between ultrasound findings, placental pathology, and prognosis in pregnancies complicated by massive subchorionic thrombohematoma (MTH)/Breus' mole.

Method: We identified 14 cases of MTH from January 2004 to December 2012. MTH was defined by >1 cm thickness hematoma and extensive (≥50%) involvement of the fetal surface of the placenta. Read More

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October 2013
18 Reads