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Cureus 2020 Apr 7;12(4):e7582. Epub 2020 Apr 7.

Pathology, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.

Struma ovarii is a variant of a germ cell tumor composed predominantly of thyroid tissue. It is most often unilateral. The incidence of malignancy arising in patients with struma ovarii is rare. Read More

Ecancermedicalscience 2020 4;14:1009. Epub 2020 Feb 4.

Department of Gynecologic Oncology, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10021, USA.

Background: Malignant transformation of mature cystic teratomas (MCTs) is a rare phenomenon. The most common histology of a malignant transformation is squamous cell carcinoma, and there are limited reports of multiple malignancies arising in a single MCT. Further data are necessary to guide management of these atypical cases. Read More

Endocrinol Diabetes Metab Case Rep 2020 Mar 13;2020. Epub 2020 Mar 13.

Department of Endocrinology, Croydon University Hospital, London, UK.

Summary: A 33-year-old female presented with a right 11.6 cm ovarian cyst. Routine pre-operative thyroid function tests showed thyroid stimulating hormone (TSH) of less than 0. Read More

Endocr Pathol 2020 Mar 2. Epub 2020 Mar 2.

Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr, 55, 45147, Essen, Germany.

Strumal carcinoid is an extraordinary rare tumor of the ovary consisting of thyroid tissue intermixed with neuroendocrine tumor component. The cellular origin of strumal carcinoids has been an area of debate. There is also little data on detailed immunohistochemical and molecular characteristics of these neoplasms. Read More

Endocrinol Diabetes Metab Case Rep 2020 Feb 14;2020. Epub 2020 Feb 14.

Cancer Genetics, Kolling Institute of Medical Research, Sydney, New South Wales, Australia.

Summary: Struma ovarii is a rare, usually benign ovarian tumour with malignancy occurring in <5% of cases. Metastases, particularly seeding to bone, are extremely rare. Presentation is variable but often features local pain and/or ascites and hyperthyroidism may occur. Read More

Gynecol Endocrinol 2020 Feb 11:1-4. Epub 2020 Feb 11.

Ivane Javakhishvili Tbilisi State University Faculty of Medicine, Tbilisi, Georgia.

Struma Ovarii is one of the types of mature teratoma, with predominant thyroid tissue (>50%). It occurs in 1% of all cases of ovarian tumors and in 2.7% of dermoid tumors. Read More

Cureus 2019 Dec 23;11(12):e6450. Epub 2019 Dec 23.

Internal Medicine, Sahiwal Medical College, Sahiwal, PAK.

Papillary thyroid carcinoma (PTC) arising in a coexistent struma ovarii (SO) is a rare malignancy. It manifests with abdominal symptoms such as palpable mass, pain, distension, and possibly ascites. It is usually diagnosed postoperatively, and its histopathological diagnostic criteria remain identical to that of papillary carcinoma of the thyroid gland. Read More

Diagnostics (Basel) 2020 Jan 15;10(1). Epub 2020 Jan 15.

Collegium Medicum, Jan Kochanowski University, IX Wieków Kielc Av.19, 25-319 Kielce, Poland.

Introduction: Struma ovarii accounts for 2% of mature teratomas. Struma ovarii is diagnosed when thyroid tissue accounts for >50% of the teratoma. Malignant transformation is rare, occurring in <5% of struma ovarii cases. Read More

Cytogenet Genome Res 2020 20;160(1):2-10. Epub 2019 Dec 20.

Strumae ovarii are neoplasms composed of normal-appearing thyroid tissue that occur within the ovary and rarely spread to extraovarian sites. A unique case of struma ovarii with widespread dissemination detected 48 years after removal of a pelvic dermoid provided the opportunity to reexamine the molecular nature of this form of neoplasm. One tumor, from the heart, consisting of benign thyroid tissue was found to have whole-genome homozygosity. Read More

Diagn Cytopathol 2020 Apr 2;48(4):360-363. Epub 2019 Dec 2.

Department of pathology, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, Pennsylvania.

Highly differentiated follicular carcinoma of ovary (HDFCO) is a rare entity known to arise in struma ovarii. Clinical presentation and radiological features mimic other cystic ovarian neoplasm. Thus, intraoperative diagnosis of this entity can be challenging. Read More

Medicine (Baltimore) 2019 Nov;98(48):e18009

Department of Gynecology and Obstetrics.

Rationale: Strumal carcinoid tumor of the ovary (SCTO) is a very rare kind of ovarian tumor. The symptoms of SCTO are often nonspecific and misleading. Therefore, a full understanding of the characteristics, diagnosis, and treatment methods of SCTO is important. Read More

Ann Endocrinol (Paris) 2019 Nov 18;80(5-6):329-331. Epub 2019 Oct 18.

Department of nuclear medicine, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France; Inserm, UMR970, Paris-Cardiovascular Research Center, 75015 Paris, France; GRC n(o) 16, GRC tumeurs thyroïdiennes, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France. Electronic address:

Arch Gynecol Obstet 2019 12 3;300(6):1693-1707. Epub 2019 Nov 3.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, Molly Siegel 550 16th Street, 7th Floor, Ob/Gyn Mailstop 0132, San Francisco, CA, 94143, USA.

Purpose: To present a case of struma ovarii with a typical features and synchronous primary thyroid carcinoma and review the available literature to guide diagnosis and management of these tumors.

Methods: We present a case from our hospital of a 55-year-old woman who had an adnexal mass with features concerning for papillary thyroid carcinoma and was ultimately determined to be struma ovarii with atypical features. Subsequent thyroid imaging and biopsy revealed a primary cervical thyroid carcinoma. Read More

Hum Pathol 2020 Jan 22;95:169-206. Epub 2019 Oct 22.

The James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

The author reviews highlights of advances in knowledge concerning ovarian tumor pathology since the time of an essay in the first issue of this Journal written by Dr Robert E. Scully, who, both before and for several decades after the Journal was instituted, made many original contributions to the field and was the major architect of the 1973 World Health Organization classification of ovarian tumors which was much more clear and logical than prior ones. The current review considers the neoplasms in essentially the same order as was done in the first issue of this journal and presents a personal look at the highlights of new information concerning various well-known categories, surface epithelial, germ cell, sex cord-stromal, metastatic neoplasms and briefly, benign so-called tumor-like lesions. Read More

Br J Neurosurg 2019 Oct 20:1-3. Epub 2019 Oct 20.

Department of Neurosurgery, King's College Hospital NHS Foundation Trust , London , UK.

Neurosurgical shunts occasionally act as a conduit for seeding of central nervous system tumours to the abdomen. Retrograde spread of extra-neural tumours to the central nervous system is exceedingly rare. We report the first case of an abdominal primary tumour spreading to the spinal cord via a lumbo-peritoneal shunt. Read More

Gynecol Oncol Rep 2019 Nov 9;30:100498. Epub 2019 Sep 9.

Department of Gynecology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

Malignant struma ovarii presenting with follicular carcinoma is extremely rare, and its mechanism of tumorigenesis remains unknown. Here, we present a case of malignant struma ovarii with peritoneal dissemination of follicular carcinoma, for which a molecular analysis for major oncogenic gene alterations in follicular thyroid carcinoma was performed. A 39-year-old nulliparous woman was referred with a diagnosis of highly differentiated follicular carcinoma of ovarian origin. Read More

Anticancer Res 2019 Sep;39(9):5053-5056

Academic Department of Gynecology and Obstetrics, University of Turin, Mauriziano Hospital, Turin, Italy.

Primary ovarian carcinoids are very rare tumors that belong to the germ cell family of ovarian malignancies. They account for less than 1% of all carcinoid tumors and for less than 0.1% of all ovarian neoplasms. Read More

G Chir 2019 May-Jun;40(3):199-207

A 19-year-old woman at 12th week of pregnancy was referred to our hospital with severe acute abdominal pain, nausea and vomiting. Patient's abdomen was untreatable. Routine examinations, except neutrophilic leukocytosis, were normal. Read More

Radiographics 2019 Jul-Aug;39(4):1019-1035. Epub 2019 May 24.

From the Departments of Radiology (K.M., M.M.H.) and Pathology (J.W.C.), Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115; Department of Radiology, Mayo Clinic Scottsdale, Scottsdale, Ariz (C.O.M.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (S.B.); and Department of Radiology, University of Texas Health Science Center, San Antonio, Tex (V.S.K.).

Germ cell tumors, because they contain immature and mature elements, can differentiate into different tissue types. They can exhibit unusual imaging features or manifest in a syndromic fashion. The authors describe these features and assign them to one of the following categories: unusual manifestations of metastatic disease (growing teratoma syndrome, choriocarcinoma syndrome, ossified metastases, and gliomatosis peritonei); autoimmune manifestations (sarcoidlike reaction and paraneoplastic syndromes); endocrine syndromes (sex hormone production, struma ovarii, and struma carcinoid); or miscellaneous conditions (ruptured dermoid cyst, squamous cell carcinoma arising from a mature teratoma, Currarino triad, fetus in fetu, pseudo-Meigs syndrome, and pancreatitis). Read More

Mol Clin Oncol 2019 Jun 15;10(6):592-596. Epub 2019 Apr 15.

Department of Obstetrics and Gynecology, Venizeleio and Pananio General Hospital of Heraklion, Heraklion 71409, Greece.

The coexistence of endometrioma with dermoid cyst of the ovaries is an unusual entity, although they are both common and benign gynecological tumors. The present study aimed to investigate the association between ovarian dermoid cyst (teratoma) and endometrioma. We retrospectively, included 315 women with endometrioma and 172 with ovarian teratoma. Read More

Case Rep Endocrinol 2019 17;2019:7964126. Epub 2019 Mar 17.

Division of Endocrinology, Diabetes & Metabolism, University of Illinois at Chicago, Chicago, IL, USA.

Objective: To present a rare case of malignant struma ovarii (MSO) and synchronous thyroid cancer, review the medical literature, and present the latest trends in management.

Methods: The case of a woman with MSO and concomitant thyroid cancer is presented, including clinical presentation, treatment, and follow-up care. A search of the English-language literature was conducted using MEDLINE and Google Scholar data bases. Read More

Folia Histochem Cytobiol 2019 29;57(1):35-42. Epub 2019 Mar 29.

Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.

Introduction: Struma ovarii (SO) is a monodermal teratoma in which thyroid tissue comprises more than 50% of the tumour. Papillary thyroid cancer (PTC) in SO is a rare finding, as only 5% of SO cases undergo malignant transformation. Malignant SO is usually asymptomatic and infrequently diagnosed preoperatively. Read More

J Obstet Gynaecol 2019 Jul 16;39(5):716-717. Epub 2019 Mar 16.

a Department of Obstetrics and Gynecology , American University of Beirut Medical Center , Beirut , Lebanon.

J Midlife Health 2018 Oct-Dec;9(4):225-229

Department of Radio-Diagnosis, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Struma ovarii is a variant of mature cystic teratoma, with predominant thyroid element. Confirmatory diagnosis is by histopathology. It may mimic as ovarian malignancy in some. Read More

Medicine (Baltimore) 2018 Dec;97(51):e13867

Department of Nuclear Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Rationale: Malignant struma ovarii is extremely rare in the clinic. The diagnosis and modalities of treatment are still controversial. Here we describe a case of extensive peritoneal implant metastasis originating from malignant struma ovarii discovered 14 years after ovariectomy and chemotherapy. Read More

Diagn Cytopathol 2019 Mar 28;47(3):218-221. Epub 2018 Nov 28.

Department of Pathology and Laboratory Medicine, Kansai Medical University, Hirakata, Japan.

Strumal carcinoid is a rare ovarian tumor defined as carcinoid associated with struma ovarii. We report here the second cytological case of strumal carcinoid and performed immunocytochemical analysis for the first time. A 68-year-old Japanese female was found to have a solid tumor with small cystic components in the left ovary, and bilateral salpingo-oophorectomy was performed. Read More

Case Rep Oncol 2018 Sep-Dec;11(3):693-698. Epub 2018 Oct 31.

Department of Gynecology and Obstetrics, Tagawa Municipal Hospital, Fukuoka, Japan.

Introduction: Malignant struma ovarii is a rare neoplasm. It is usually asymptomatic and not commonly diagnosed preoperatively. In addition, there is currently no established diagnostic and therapeutic approach for malignant struma ovarii. Read More

Clin Nucl Med 2019 Jan;44(1):42-44

Institute of Pathology, Essen University Hospital, Essen, Germany.

A 67-year-old woman presented with malignant struma ovarii after radical bilateral salpingo-oophorectomy. The surgery revealed a 4.4 cm papillary thyroid carcinoma (follicular variant) within a right-sided ovarian teratoma. Read More

Am J Forensic Med Pathol 2019 Mar;40(1):89-93

Department of Clinical Pathology, ASL 1 Imperiese - Sanremo Hospital, Sanremo, Italy.

Meigs syndrome is the triad of ascites, hydrothorax, and benign ovarian tumor (mostly fibroids). It is a diagnosis of exclusion, and the characteristic symptoms disappear after resection of the tumor. Instead, in Pseudo-Meigs syndrome, the triad includes a nonfibroma ovarian tumor. Read More

Zhonghua Bing Li Xue Za Zhi 2018 09;47(9):733-736

Int J Surg Case Rep 2018 5;51:218-220. Epub 2018 Sep 5.

Pathology Department, Ardabil University of Medical Sciences, Ardabil, Iran.

Introduction: Struma ovarii is an ovarian tumor with thyroid tissue as its predominant component. It usually occurs in older women and presents with abdominal mass, pain and abnormal bleeding. Most patients are euthyroid, but some reports have noted thyrotoxicosis originating from the malignant struma ovarii. Read More

Med Ultrason 2018 Aug;20(3):355-361

Department of Gynecology and Obstetrics Charles University in Prague-First Faculty of Medicine and Hospital Na Bulovce, Czech Republic.

Aims: To describe the ultrasound features of benign struma ovarii that often mimic ovarian cancer in the background of complex clinical and histopathological pictures.

Material And Methods: We retrospectively identified patients with histologically confirmed benign struma ovarii, treated in our institution between 2003-2016 with complete imaging, clinical, nd histopathological data available. Ultrasound findings were drawn from images, and reports using terms and definitions of the International Ovarian Tumor Analysis group and pattern recognition description was applied. Read More

J Reprod Infertil 2018 Jul-Sep;19(3):174-181

Department of Assisted Reproduction, Hospital Quironsalud Malaga, Malaga, Spain.

Background: Cryopreservation of oocytes is an efficient method of fertility preservation (FP) that can be applied in women suffering from gynecologic conditions that menace their reproductive future. Collection of oocytes becomes challenging in some scenarios, like the possibility of an ovarian cancer, the "" harvest of oocytes for FP, aspirating follicles directly from the ovarian specimen already excised by laparotomy or laparoscopy and it is an option for these cases.

Case Presentation: In the present case report, the case of a patient with an adnexal mass suspected to be a recurrent teratoma was described who referred to our Assisted Reproduction Unit in Hospital Quironsalud Malaga for FP counseling. Read More

Int J Gynecol Pathol 2019 Nov;38(6):576-580

Department of Histopathology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry (S.S.) Department of Pathology (W.G.M.), Belfast Health and Social Care Trust, Belfast, Northern Ireland UK.

Brenner tumors are uncommon ovarian neoplasms which occasionally occur in combination with a mucinous tumor. Rarely, the combination of Brenner tumor and thyroid tissue (struma ovarii) has been reported. We report an ovarian neoplasm with components of Brenner tumor, mucinous cystadenoma and struma ovarii. Read More

J Endocr Soc 2018 Aug 10;2(8):944-948. Epub 2018 Jul 10.

Department of Medicine, Endocrinology Section, MedStar Washington Hospital Center, Washington, DC.

Struma ovarii is a rare ovarian teratoma predominantly composed of thyroid tissue. The simultaneous presence of thyroid carcinoma in the struma ovarii and the thyroid gland is extremely rare. It remains unclear if these carcinomas represent independent primary tumors and whether the molecular mechanisms of the tumors developing in the thyroid and ovarian tissues are similar. Read More

Thyroid Res 2018 24;11:10. Epub 2018 Jul 24.

1Department of General Surgery, Hamad General Hospital, Doha, Qatar.

Background: Malignant struma ovarii (MSO) is a very rare, germ cell tumor of the ovary, histologically identical to differentiated thyroid cancers. Struma ovarii (SO) is difficult to diagnose on clinical basis or imaging and is mostly discovered incidentally, with few published cases in the literature.

Case Presentation: A 42-year old primiparous woman presented with abdominal pain and midline pelvic palpable firm mass arising from the pelvis. Read More

Zhonghua Bing Li Xue Za Zhi 2018 Jul;47(7):517-521

Department of Pathology, Fudan University Shanghai Cancer Center, Department of Oncology; Shanghai Medical College, Fudan University, Shanghai 200032, China.

To describe the clinicopathologic features, diagnosis and differential diagnosis of ovarian carcinoid tumors. A retrospective chart review was performed of all patients diagnosed with primary ovarian carcinoid tumors at Fudan University Shanghai Cancer Centre from 2007 to 2017. The histologic analysis of these carcinoid tumors revealed 3 were insular, 1 was trabecular, 1 was mucinous, and 10 were strumal. Read More

Clin Diabetes Endocrinol 2018 19;4:13. Epub 2018 Jun 19.

4Department of Nuclear Medicine, University of Michigan, 1500 E Medical Center Dr, B1G505, Ann Arbor, MI 48109-5028 USA.

Background: Malignant struma ovarii is an ovarian teratoma containing at least 50% thyroid tissue which has the potential to metastasize and produce thyroid hormone. Given its rarity, management strategies are not well-established. We report a case of metastatic malignant struma ovarii discovered during pregnancy with lessons for evaluation and management. Read More

Anticancer Res 2018 Jun;38(6):3669-3675

Department of New Technologies and Translational Research, Division of Pathology, University of Pisa, Pisa, Italy.

Malignant transformation occurs in 1.5-2% of mature cystic teratomas (MCT)s of the ovary and usually consists of squamous cell carcinoma, whereas other malignancies are less common. Diagnosis and treatment represent a challenge for gynecologic oncologists. Read More

JBJS Case Connect 2018 Apr-Jun;8(2):e35

Zhonghua Bing Li Xue Za Zhi 2018 May;47(5):339-343

Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

To study the clinicopathologic feature, diagnostic strategy and prognostic significance of primary carcinoid of the ovary (PCOTO). A series of 17 patients previously diagnosed as PCOTO at Department of Pathology, Peking Union Medical College Hospital during the period from 2002 to 2017 were evaluated with clinical data analysis, histopathology and immunohistochemistry, and the patients were followed up and the relevant literatures were reviewed. The age of patients ranged from 24 to 64 years (mean, 42 years). Read More

Gynecol Oncol Rep 2018 May 19;24:87-89. Epub 2018 Apr 19.

Division of Gynecologic Oncology, Brooke Army Medical Center, 3551 Roger Brooke Drive, San Antonio, TX 78234, United States.

•Peritoneal strumosis is highly differentiated thyroid follicular carcinoma of ovarian origin.•Minimally invasive surgical techniques for peritonectomy can resect extra-ovarian disease.•Multi-disciplinary collaboration allowed avoidance of thyroid ablation and thyroidectomy. Read More

Bull Cancer 2018 Mar 17;105(3):281-289. Epub 2018 Feb 17.

Institut Bergonié, département de médecine nucléaire et de cancérologie thyroidienne, 229, cours de l'Argonne, 33076 Bordeaux, France.

Thyroid carcinoma on struma ovarii (TCSO) is a rare ovarian tumour, derivate from monodermic teratomas. It represents about 0.01% of overall ovarian tumours and 5 to 10% of struma ovarii. Read More

Virchows Arch 2018 Aug 17;473(2):177-182. Epub 2018 Feb 17.

Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, 5 Zaifu, Hirosaki, 036-8562, Japan.

Although ovarian monodermal teratomas, including struma ovarii and carcinoids, are closely associated with mature teratomas, their genetic basis is poorly understood. A series of mature and monodermal ovarian teratomas were analyzed by short tandem repeat genotyping to evaluate their genetic zygosity and its associations. Informative DNA genotyping data were obtained for ten mature teratomas, six struma ovarii, and three carcinoids (one insular, one trabecular, and one mucinous). Read More

J Ovarian Res 2018 Feb 2;11(1):11. Epub 2018 Feb 2.

Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan.

Background: Struma ovarii is a rare ovarian neoplasm that often appears malignant on conventional imaging. Pseudo-Meigs' syndrome with ascites, pleural effusion, and elevated serum CA 125 levels is much rarer and leads to misdiagnosis of ovarian cancer and unnecessary extended surgery.

Case Presentation: A 50-year-old woman with abdominal distention and dyspnoea was referred to our hospital. Read More

Medicina (B Aires) 2018;78(1):44-46

Servicio de Endocrinología, Servicio de Endocrinología y Metabolismo, Complejo Médico Churruca-Visca, Buenos Aires, Argentina.

Hyperthyroidism is defined as an excessive production of thyroid hormones by eutopic or ectopic mature thyroid tissue. The overall prevalence of hyperthyroidism is 1.2% and the most common cause is Graves' disease. Read More

Gynecol Endocrinol 2018 Jul 10;34(7):558-562. Epub 2018 Jan 10.

a Gynecology and Physiopathology of Human Reproductive Unit , University of Bologna, S. Orsola-Malpighi Hospital of Bologna , Bologna , Italy.

In this case report, the outcomes of cryopreserved ovarian tissue transplantation performed in a patient affected by struma-ovarii associated with mature cystic teratoma, recurrent endometriotic cysts and diffuse peritoneal malignant struma-ovarii implants were described. Before cryopreservation, the patient underwent two left ovarian surgeries for enucleation cysts 8 years after righ salpingo-oophorectomy for struma-ovarii. Ovarian biopsy was collected in another hospital and transported to our laboratory for cryopreservation. Read More

J Radiol Case Rep 2017 Jul 31;11(7):20-30. Epub 2017 Jul 31.

Serviço de Anatomia Patológica, Instituto Portugues de Oncologia de Lisboa Francisco Gentil, Lisboa, Portugal.

We describe a case of a mature cystic teratoma of the ovary with high proportion of solid thyroid tissue (< 50% of the entire tumor) in a childbearing woman. The patient presented with non-specific abdominal bloating. Pelvic ultrasound and magnetic resonance imaging revealed a complex cystic-solid tumor confined to the left ovary with an anterior fat-containing locus compatible with mature cystic teratoma and a posterior predominantly solid component with low signal intensity on T2-weighted images that was histopatologically diagnosed as benign thyroid tissue. Read More

Ceska Gynekol Winter 2018;83(6):452-457

Objective: Strumal carcinoid (SC) is a rare ovarian germ-cell tumour, which is characterized by a mixture of thyroid tissue and carcinoid. It can be presented as a monodermal teratoma or as a part of mature cystic teratoma (dermoid cyst).

Design: Case report. Read More

JBJS Case Connect 2017 Oct-Dec;7(4):e82

Departments of Orthopaedic Oncology (J.C., F.F.E.P., S.A.N., and W.T.C.), and Pathological Anatomy (F.D.C. and A.D.B.), AC Camargo Cancer Center, São Paulo, Brazil.

Case: We report the case of a 38-year-old woman who presented with a lytic bone lesion in the left scapula. A biopsy showed a tumor with the histologic appearance of thyroid tissue. She also was found to have a thyroid nodule and an enlarged ovary, both of which were excised. Read More