1,414,445 results match your criteria Structure London England : 1993[Journal]


UV LEDs based on p-i-n core-shell AlGaN/GaN nanowire heterostructures grown by N-polar selective area epitaxy.

Nanotechnology 2019 Feb 18. Epub 2019 Feb 18.

National Institute of Standards and Technology, Boulder, Colorado, UNITED STATES.

Ultraviolet light-emitting diodes (UV LEDs) fabricated from N-polar AlGaN/GaN core-shell nanowires with p-i-n structure produced electroluminescence at 365 nm with ~5x higher intensities than similar GaN homojunction LEDs. The improved characteristics were attributed to localization of spontaneous recombination to the nanowire core, reduction of carrier overflow losses through the nanowire shell, and elimination of current shunting. Poisson-drift-diffusion modeling indicated that a shell Al mole fraction of x=0. Read More

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http://dx.doi.org/10.1088/1361-6528/ab07edDOI Listing
February 2019

Controllable fiber orientation and nonlinear elasticity of electrospun nanofibrous small diameter tubular scaffolds for vascular tissue engineering.

Biomed Mater 2019 Feb 18. Epub 2019 Feb 18.

Advanced Polymer Processing Technology of National Engineering Research Center, Zhengzhou University, Zhengzhou, Henan, CHINA.

Biomimetic structures play an important role in controlling the cell behaviors of adhesion, proliferation, migration, and differentiation, which is beneficial for the regeneration of defective tissues. Scaffolds with a biomimetic structure are highly desirable in tissue engineering. In this study, we successfully fabricated three different types of tubular scaffold with randomly, circumferentially, and axially aligned structures, using synthetic bioabsorbable poly(L-lactide-co-caprolactone) via electrospinning. Read More

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http://dx.doi.org/10.1088/1748-605X/ab07f1DOI Listing
February 2019

3D ordered mesoporous TiO2@CMK-3 nanostructure for sodium-ion batteries with long-term and high-rate performance.

Nanotechnology 2019 Feb 18. Epub 2019 Feb 18.

School of Science, Xi'an Jiaotong University, Xi'an, Shaanxi, CHINA.

Abstract:Sodium ion battery is abundant in resources and costs low, making it very competitive in the large-scale energy storage devices. The anatase TiO2 electrode material with insertion/extraction mechanism shows stable cycling performance,which is more in line with the technical requirements of large-scale energy storage batteries. To improve the electrical conductivity and stability of the TiO2 electrode materials, we have synthesized anatase TiO2 and CMK-3 composite. Read More

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http://dx.doi.org/10.1088/1361-6528/ab0812DOI Listing
February 2019

Role of surface charges on interaction of rod-shaped magnetic hydroxyapatite nanoparticles with protein.

Colloids Surf B Biointerfaces 2019 Feb 12;177:362-369. Epub 2019 Feb 12.

Department of Chemical Engineering, BITS Pilani K K Birla Goa Campus, India. Electronic address:

Magnetic hydroxyapatite (MHAp) exhibits excellent biocompatibility, making it an ideal candidate as a biomaterial. Recent investigations have shown that the combined effect of magnetite and hydroxyapatite nanostructures provide efficient means for diagnostic and therapeutic applications which can be controlled with an external magnetic field. For these applications an important aspect to be considered is the interaction of the MHAp nanoparticles (NPs) with biomolecules such as protein (P) and the subsequent biological response. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.02.021DOI Listing
February 2019

Modeling MesoBioNano systems with MBN Studio made easy.

J Mol Graph Model 2019 Feb 7;88:247-260. Epub 2019 Feb 7.

MBN Research Center, Altenhöferallee 3, 60438, Frankfurt am Main, Germany. Electronic address:

This paper introduces MesoBioNano (MBN) Studio - a graphical user interface for a popular multiscale simulation package MBN Explorer. MBN Studio has been developed to facilitate setting up and starting MBN Explorer calculations, monitoring their progress and examining the calculation results. It is tailored for any calculations that are supported by MBN Explorer, such as for example the single-point energy calculations, structure optimization, molecular dynamics, and kinetic Monte Carlo simulations. Read More

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http://dx.doi.org/10.1016/j.jmgm.2019.02.003DOI Listing
February 2019

Structural investigation of α-l-fucosidase from the pancreas of Patiria pectinifera, based on molecular cloning.

Carbohydr Res 2019 Feb 7;475:27-33. Epub 2019 Feb 7.

Department of Applied Chemistry and Biochemistry, National Institute of Technology, Fukushima College, 30 Nagao, Iwaki, Fukushima, 970-8034, Japan. Electronic address:

An α-l-fucosidase (Pap-Alf) was purified from the pancreas of a starfish Patiria pectinifera by ammonium sulfate precipitation followed by several column chromatographies. The molecular mass of the purified enzyme was estimated to be 52.6 kDa by SDS-PAGE, although gel filtration analysis of the native enzyme suggests it exists as a homodimer in solution. Read More

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http://dx.doi.org/10.1016/j.carres.2019.02.001DOI Listing
February 2019

Confronting variability with uncertainty in the ecotoxicological impact assessment of down-the-drain products.

Environ Int 2019 Feb 15;126:37-45. Epub 2019 Feb 15.

Department of Environmental Science, Institute for Water and Wetland Research, Radboud University Nijmegen, P.O. Box 9010, 6500, GL, Nijmegen, the Netherlands.

The use of down-the-drain products and the resultant release of chemicals may lead to pressures on the freshwater environment. Ecotoxicological impact assessment is a commonly used approach to assess chemical products but is still influenced by several uncertainty and variability sources. As a result, the robustness and reliability of such assessments can be questioned. Read More

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http://dx.doi.org/10.1016/j.envint.2019.01.080DOI Listing
February 2019

Dietary exposure to polychlorinated biphenyls and risk of heart failure - A population-based prospective cohort study.

Environ Int 2019 Feb 15;126:1-6. Epub 2019 Feb 15.

Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden. Electronic address:

Background: Beneficial effects of fish consumption on heart failure (HF) may be modified by contaminants in fish. Polychlorinated biphenyls (PCBs) are of particular concern as they have been associated with well-established risk factors of HF, but current data are limited.

Objectives: We aimed to assess the association between dietary PCB exposure and risk of HF, accounting for dietary intake of long-chain omega-3 fish fatty acids. Read More

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http://dx.doi.org/10.1016/j.envint.2019.01.069DOI Listing
February 2019

The mechanism of phase transitions in azide perovskites probed by vibrational spectroscopy.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Feb 11;214:184-191. Epub 2019 Feb 11.

Institute of Low Temperature and Structure Research PAS, Okólna Str. 2, 50-422 Wrocław, Poland.

The temperature-dependent IR and Raman spectroscopy has been used to study the phase transitions in manganese-azide frameworks with either dimethylammonium (DMA) or tetramethylammonium (TMA) cations which adopt a perovskite-like crystal structure. The phase transition in DMA-analogue seems to be associated with cooperative tilting of MnN octahedra and order-disorder of hydrogen bonds while in TMA-analogue it is more complex and composed of several processes, including the motions of both manganese-azide framework and tetramethylammonium cations and their possible coupling. Our results are in agreement with the data received from crystallographic and dielectric measurements in the case of TMA-analogue and we have demonstrated the importance of order-disorder of hydrogen bonds in the case of DMA-analogue which previously has not been taken into account. Read More

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http://dx.doi.org/10.1016/j.saa.2019.02.027DOI Listing
February 2019

Ozone initiated heterogeneous oxidation of unsaturated carboxylic acids by ATR-FTIR spectroscopy.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Feb 12;214:177-183. Epub 2019 Feb 12.

Department of Chemistry, University of Colorado Denver, Denver, CO, 80217, USA. Electronic address:

Despite considerable effort has been directed to ozone-initiated heterogeneous oxidation of unsaturated organic species in atmospheric environment, current knowledge about how chemical structure of unsaturated carboxylic acids affects their reaction kinetics remains very limited. Here, kinetics of heterogeneous reaction of ozone with six unsaturated fatty acids (oleic acid, vaccenic acid, eladic acid, myristoleic acid, palmitoleic acid and 2-hexadecenoic acid) were studied via a flow system combined with attenuated total reflection Fourier-transformed infrared spectroscopy (ATR-FTIR). Pseudo-first-order rate constants (k) and overall reactive uptake coefficients (γ) values were derived according to the changes in absorbance from infrared spectra. Read More

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http://dx.doi.org/10.1016/j.saa.2019.02.025DOI Listing
February 2019

Maslinic acid conjugate with 7-amino-4-methylcoumarin as probe to monitor the temperature dependent conformational changes of human serum albumin by FRET.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Feb 11;214:161-169. Epub 2019 Feb 11.

Department of Organic Chemistry, University of Granada, 18071 Granada, Spain.

Synthesis, characterization and spectroscopic investigation of maslinic acid labeled with fluorescent 7-amino-4-methylcoumarin is reported. It was found that the coumarin-maslinic derivative (MaCo) forms an excellent fluorescence resonance energy transfer (FRET) pair with the tryptophan (Trp) residue of human serum albumin (HSA). This feature allowed for monitoring HSA conformational alterations by measuring the distance between donor (Trp) and acceptor (MaCo) through Förster energy transfer mechanism. Read More

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http://dx.doi.org/10.1016/j.saa.2019.02.014DOI Listing
February 2019

Synthesis and living cell imaging of a novel fluorescent sensor for selective cupric detection.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Feb 11;214:146-151. Epub 2019 Feb 11.

Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, College of Life Sciences, Fujian Normal University, 1 Keji Road, Fuzhou 350117, PR China. Electronic address:

Copper is an important element indispensable for human life and health. Many copper-determining probes have been created for exploring its functional behavior in various cell types but few of them contains both fluorescent and colorimetric characters. In the present study, we developed a set of copper probes by synthesizing several novel thiophene-based Schiff bases in order to make a suitable sensor for quantifying and imaging copper in living cells. Read More

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http://dx.doi.org/10.1016/j.saa.2019.02.013DOI Listing
February 2019

Revealing quinquennial anticancer journey of morpholine: A SAR based review.

Eur J Med Chem 2019 Feb 8;167:324-356. Epub 2019 Feb 8.

Drug Design & Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India. Electronic address:

Morpholine, a six-membered heterocycle containing one nitrogen and one oxygen atom, is a moiety of great significance. It forms an important intermediate in many industrial and organic syntheses. Morpholine containing drugs are of high therapeutic value. Read More

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http://dx.doi.org/10.1016/j.ejmech.2019.02.015DOI Listing
February 2019

Design, synthesis and biological evaluation of (E)-5-styryl-1,2,4-oxadiazoles as anti-tubercular agents.

Bioorg Chem 2019 Feb 7;86:507-512. Epub 2019 Feb 7.

Chemistry of Heterocycles & Natural Product Research Laboratory, Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore 632014, Tamil Nadu, India. Electronic address:

Cinnamic acid and its derivatives are known for anti-tubercular activity. The present study reports the synthesis of cinnamic acid derivatives via bioisosteric replacement of terminal carboxylic acid with "oxadiazole". A series of cinnamic acid derivatives (styryl oxadiazoles) were designed and synthesized in good yields by reaction of substituted cinnamic acids (2, 15a-15s) with amidoximes. Read More

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http://dx.doi.org/10.1016/j.bioorg.2019.01.054DOI Listing
February 2019

Mental Pain Questionnaire: An item response theory analysis.

J Affect Disord 2019 Feb 11;249:226-233. Epub 2019 Feb 11.

Department of Health Sciences, University of Florence, Italy; Department of Psychiatry & Neuropsychology, Maastricht University, Maastricht, the Netherlands. Electronic address:

Background: The Mental Pain Questionnaire (MPQ) is a self-report questionnaire developed to assess mental pain. The aim of the present study was to test the clinimetric properties of the MPQ.

Methods: A sample of 200 migraine outpatients were enrolled; homogeneity of MPQ was assessed by Mokken Analysis; item-level severity and item-level sensitivity were calculated via Two-Parameter Logistic model; Total Information Function was evaluated to assess reliability of MPQ; internal consistency was calculated via Cronbach's alpha and Sijtsma and Molenaar rho; sensitivity and specificity were assessed via Receiver Operating Characteristic curves. Read More

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http://dx.doi.org/10.1016/j.jad.2019.02.030DOI Listing
February 2019

Mechanism of biomass activation and ammonia modification for nitrogen-doped porous carbon materials.

Bioresour Technol 2019 Feb 7;280:260-268. Epub 2019 Feb 7.

State Key Laboratory of Coal Combustion, School of Power and Energy Engineering, Huazhong University of Science and Technology, 430074 Wuhan, China. Electronic address:

The effect of chemical activation and NH modification on activated carbons (ACs) was explored via two contrasting bamboo pyrolysis strategies involving either two steps (activation followed by nitrogen doping in NH atmosphere) or one step (activation in NH atmosphere) with several chemical activating reagents (KOH, KCO, and KOH + KCO). The ACs produced by the two-step method showed relatively smaller specific surface areas (∼90% micropores) and lower nitrogen contents. From the one-step method, the ACs had larger pore diameters with about 90% small mesopores (2-3. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.02.039DOI Listing
February 2019

Butterfly cluster like lamellar BiOBr/TiO nanocomposite for enhanced sunlight photocatalytic mineralization of aqueous ciprofloxacin.

Sci Total Environ 2019 Feb 11;665:668-677. Epub 2019 Feb 11.

Department of Environmental Sciences, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Central Metallurgical R&D Institute, Helwan 11421, Cairo, Egypt.

The present study for the first time reports facile in-situ room temperature synthesis of butterfly cluster like lamellar BiOBr deposited over TiO nanoparticles for photocatalytic breakdown of ciprofloxacin (CIP). The butterfly cluster arrangement of BiOBr resulted in an increase in surface area from 124.6 to 160. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.145DOI Listing
February 2019

Numerical modelling of the suspended particulate matter dynamics in a regulated river network.

Sci Total Environ 2019 Feb 10;665:591-605. Epub 2019 Feb 10.

Irstea, UR RiverLy, 5 rue de la Doua CS 20244, Villeurbanne Cedex 69625, France. Electronic address:

Understanding and predicting the propagation, deposition and resuspension of suspended particulate matter (SPM) in river networks is important for managing water resources, ecological habitat, pollution, navigation, hydropower generation, reservoir sedimentation, etc. Observational data are scarce and costly, and there is little feedback on the efficiency of numerical simulation tools for compensating the lack of data on a river scale of several hundreds of kilometers. This paper aims at exploring the use of a one-dimensional (1-D) hydrodynamical model for understanding the source and fate of SPM during complex events. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.015DOI Listing
February 2019

Palladium nanoparticles decorated on amine functionalized graphene nanosheets as excellent nanocatalyst for the hydrogenation of nitrophenols to aminophenol counterparts.

J Hazard Mater 2019 Feb 10;369:96-107. Epub 2019 Feb 10.

Department of Chemistry, Van Yüzüncü Yıl University, Van, 65080, Turkey.

We reported the improved catalytic property of Pd (0) nanoparticles decorated on amine-functionalized graphene nanosheets (Pd/GNS-NH) for the hydrogenation of nitrophenol derivatives in the presence of NaBH at moderate conditions. Pd/GNS-NH nanocatalyst was synthesized by the deposition-reduction method. Sundry techniques such as ICP-OES, P-XRD, XPS, TEM, HR-TEM and EDX have been applied to explain the structure and morphology of the Pd/GNS-NH nanocatalyst. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.02.027DOI Listing
February 2019

3D hierarchical graphene oxide-NiFe LDH composite with enhanced adsorption affinity to Congo red, methyl orange and Cr(VI) ions.

J Hazard Mater 2019 Feb 6;369:214-225. Epub 2019 Feb 6.

Department of Science and Environmental Studies and State Key Laboratory in Marine Pollution, The Education University of Hong Kong, Tai Po, N. T. Hong Kong, PR China. Electronic address:

Three-dimensional (3D) hierarchical graphene oxide-NiFe layered double hydroxide (GO-NiFe LDH) composite with sandwich-like structure is fabricated using a facile one-pot hydrothermal reaction. Electron microscopy images demonstrate that the GO-NiFe LDH composite possesses a highly porous and well-ordered structure. Both sides of the GO are fully covered by the LDH nanosheets, resulting in the sandwich-like architecture. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.02.013DOI Listing
February 2019

Inclusion complex of saikosaponin-d with hydroxypropyl-β-cyclodextrin: Improved physicochemical properties and anti-skin cancer activity.

Phytomedicine 2018 Nov 8;57:174-182. Epub 2018 Nov 8.

Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan. Electronic address:

Background: Saikosaponin-d (SSD) is a triterpene saponin isolated from Bupleurum plants. It has been shown to exhibit antioxidant, anti-inflammatory, and anticancer activities. However, its biomedical applications are limited by its poor water solubility. Read More

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http://dx.doi.org/10.1016/j.phymed.2018.11.012DOI Listing
November 2018

Toxicity profiling of 24 l-phenylalanine derived ionic liquids based on pyridinium, imidazolium and cholinium cations and varying alkyl chains using rapid screening Vibrio fischeri bioassay.

Ecotoxicol Environ Saf 2019 Feb 14;172:556-565. Epub 2019 Feb 14.

Laboratory of Environmental Toxicology, National Institute of Chemical Physics and Biophysics, Tallinn 12618, Estonia; Estonian Academy of Sciences, Kohtu 6, Tallinn 10130, Estonia. Electronic address:

A library of 24 pyridinium-, imidazolium-, and cholinium-based ionic liquids (ILs) with varying alkyl chain from C to C was toxicologically profiled using naturally luminescent marine bacteria Vibrio fischeri. The toxicity (30-min EC) of studied ILs to Vibrio fischeri ranged from 7.82 µM (4. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2018.12.076DOI Listing
February 2019

Insights into pesticide toxicity against aquatic organism: QSTR models on Daphnia Magna.

Ecotoxicol Environ Saf 2019 Feb 15;173:285-292. Epub 2019 Feb 15.

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China. Electronic address:

The toxicities of agrochemicals to non-target aquatic organisms are key items in chemical ecological risk assessment. However, it is still an urgent need to develop new tools to assess the agrochemical aquatic toxicity efficiently and accurately. In this work, QSTR studies were performed on a data set containing 639 diverse pesticides with measured EC toxicity against Daphnia magna, by using five machine learning methods combined with seven fingerprints and a set of molecular descriptors. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.02.014DOI Listing
February 2019

Paleoecological and historical data as an important tool in ecosystem management.

J Environ Manage 2019 Feb 15;236:755-768. Epub 2019 Feb 15.

Laboratory of Wetland Ecology and Monitoring & Department of Biogeography and Paleoecology, Adam Mickiewicz University, Bogumiła Krygowskiego 10, 61-680, Poznań, Poland.

In recent decades, it has been observed that most forest fires in Europe were caused by people. Extreme droughts, which are more often prolonged, can increase the risk of forest fires, not only in southern Europe but also, in Central Europe. Nonetheless, catastrophic fire events are not well recognized in the Central European Lowlands (CEL), where large forest complexes are located. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.002DOI Listing
February 2019

Development and psychometric properties of the assessment questionnaire for the process of the tutorial action plan.

Nurse Educ Today 2019 Feb 13;76:109-117. Epub 2019 Feb 13.

Campus Docent Sant Joan de Déu-Fundació Privada, School of Nursing, University of Barcelona, Barcelona, Spain; Research Group GIES (Grupo de investigación en Enfermería, Educación y Sociedad), Spain; Research Committee of the Campus Docent SJD, Spain; Neonatal and Pediatric Hospital Pedagogy Research Group, Spain.

Background: Internationally, most countries recognize the right of the student to receive assistance from teachers and tutors. The Tutorial Action Plan is a teaching tool that aims to promote academic, personal, and professional development in students. It is important to monitor this process of tutoring to be able to provide appropriate guidance to nursing students throughout their education. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.02.002DOI Listing
February 2019

I feel what I do: Relating interoceptive processes and reward-related behavior.

Neuroimage 2019 Feb 16. Epub 2019 Feb 16.

Department of Psychology, General and Experimental Psychology Unit, Ludwig-Maximilians University, D-80802, Munich, Germany.

Interoceptive signalling has been shown to contribute to action regulation and action experience. Here, we assess whether motor behaviour can be influenced by anticipated homeostatic feeling states induced through different predictable contexts. Participants performed a reward incentive paradigm in which accurate responses increased (gain) or avoided the depletion (averted loss) of a credit score. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2019.02.032DOI Listing
February 2019

Effects of silver diammine fluoride/potassium iodide on artificial root caries lesions with adjunctive application of proanthocyanidin.

Acta Biomater 2019 Feb 15. Epub 2019 Feb 15.

Melbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia. Electronic address:

Treatment of carious root surfaces remains challenging due to the complex pathological processes and difficulty in restoring the original structure of root dentine. Current treatments targeting the de-/re-mineralisation processes are not entirely satisfactory in terms of the protection of the dentinal organic matrix and the highly organised structure of dentine. In this in vitro study, a cross-linking agent - proanthocyanidin (PA) was used in conjunction with a fluoride-based treatment - silver diammine fluoride/potassium iodide (SDF/KI) to putatively stabilise the organic dentinal framework as well as strengthen the collagen-mineral phase interaction. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.02.020DOI Listing
February 2019

Local inhibition of uptake transporters augments stress-induced increases in serotonin in the rat central amygdala.

Neurosci Lett 2019 Feb 15. Epub 2019 Feb 15.

Department of Biology and Neuroscience Group, University of South Dakota, Vermillion, SD 57069, USA. Electronic address:

Organic cation transporter 3 (OCT3) is a corticosterone-sensitive, low-affinity, high-capacity transporter. This transporter functions, in part, to clear monoamines, including serotonin (5-HT), from the extracellular space. The central nucleus of the amygdala (CeA) is an important structure controlling fear- and anxiety-related behaviors. Read More

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http://dx.doi.org/10.1016/j.neulet.2019.02.022DOI Listing
February 2019

Biosynthesis of silver nanoparticle using extract of Zea mays (corn flour) and investigation of its cytotoxicity effect and radical scavenging potential.

J Photochem Photobiol B 2019 Jan 17;193:1-7. Epub 2019 Jan 17.

Research Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Ilsandong-gu, Gyeonggi-do 10326, Republic of Korea. Electronic address:

Silver nanoparticles (AgNPs) possesses a number of exceptional pharmaceutical properties and applications as compared with other types of metallic nanoparticles. Currently, AgNPs was biosynthesized using an aqueous extract of Zea mays L. (corn flour) powder. Read More

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http://dx.doi.org/10.1016/j.jphotobiol.2019.01.008DOI Listing
January 2019

Fabrication of dual network self-healing alginate/guar gum hydrogels based on polydopamine-type microcapsules from mesoporous silica nanoparticles.

Int J Biol Macromol 2019 Feb 15. Epub 2019 Feb 15.

School of Chemistry and Materials Science, Ludong University, Key Laboratory of High Performance and Functional Polymer in the Universities of Shandong Province, Collaborative Innovation Center of Shandong Province for High Performance Fibers and Their Composites, Yantai, China.

In this manuscript, dual network self-healing alginate/guar gum hydrogels with polydopamine-type microcapsules from mesoporous silica nanoparticles were facilely prepared through one-pot method. Glutaraldehyde (GA) was used as a crosslinking agent to crosslink guar gum and sodium alginate, respectively. Metal-ligand interactions as reversible non-covalent bond make the dual network hydrogels have a high degree of self-healing ability, which FeCl·6HO was coordinated with sodium alginate and polydopamine on the surface of microcapsules, respectively. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.02.089DOI Listing
February 2019

Fabrication and characterization of collagen-heparin-polypyrrole composite conductive film for neural scaffold.

Int J Biol Macromol 2019 Feb 15. Epub 2019 Feb 15.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China. Electronic address:

In this work, a conductive film consisted of polypyrrole-heparin-collagen (PHC film) was fabricated as a potential neural scaffold. Heparin was initially modified with pyrrole, which was further polymerized with pyrrole monomer under the catalysis of ferric trichloride. Then collagen was added and crosslinked through amide bond, as well as physical interaction with pyrrole through hydrogen bond. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.02.087DOI Listing
February 2019

EsTrx-2, the mitochondrial thioredoxin from Antarctic microcrustacean (Euphausia superba): Cloning and functional characterization.

Comp Biochem Physiol B Biochem Mol Biol 2019 Feb 15. Epub 2019 Feb 15.

College of Marine Science and Biological Engineering, Qingdao University of Science & Technology, Shandong, Provincial Key Laboratory of Biochemical Engineering, Qingdao 266042, China.

Thioredoxin system plays an important role in antioxidative stress, thioredoxin 2 (Trx2) being one of the most important components in the thioredoxin system. The full-length cDNA sequence of thioredoxin 2 from Euphausia superba (EsTrx2) is 1276 bp and contain a 5' untranslated region (UTR) of 94 bp, a 3' UTR of 741 bp and an open reading frame (ORF) of 441 bp, encoding a putative protein of 146 amino acids. Multiple sequence alignments have indicated that EsTrx2 possesses a conserved (-Cys-Gly-Pro-Cys-) CGPC redox-active site. Read More

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http://dx.doi.org/10.1016/j.cbpb.2019.01.014DOI Listing
February 2019

Relative Binding Affinity Prediction of Charge-Changing Sequence Mutations with FEP in Protein-Protein Interfaces.

J Mol Biol 2019 Feb 15. Epub 2019 Feb 15.

Department of Chemistry, Columbia University, 3000 Broadway, MC 3178, New York, NY 10027, USA.

Building on the substantial progress that has been made in using free energy perturbation (FEP) methods to predict the relative binding affinities of small molecule ligands to proteins, we have previously shown that results of similar quality can be obtained in predicting the effect of mutations on the binding affinity of protein-protein complexes. However, these results were restricted to mutations which did not change the net charge of the side chains due to known difficulties with modeling perturbations involving a change in charge in FEP. Various methods have been proposed to address this problem. Read More

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http://dx.doi.org/10.1016/j.jmb.2019.02.003DOI Listing
February 2019

Collagen fiber structure guides 3D motility of cytotoxic T lymphocytes.

Matrix Biol 2019 Feb 15. Epub 2019 Feb 15.

Department of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences in Oncology Center, Johns Hopkins University, Baltimore, MD, USA; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

Lymphocyte motility is governed by a complex array of mechanisms, and highly dependent on external microenvironmental cues. Tertiary lymphoid sites in particular have unique physical structure such as collagen fiber alignment, due to matrix deposition and remodeling. Three dimensional studies of human lymphocytes in such environments are lacking. Read More

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http://dx.doi.org/10.1016/j.matbio.2019.02.003DOI Listing
February 2019

Optimizing the Total Body Skin Exam: An Observational Cohort Study.

J Am Acad Dermatol 2019 Feb 15. Epub 2019 Feb 15.

Penn State Health Hershey Medical Center Department of Dermatology; Hershey, PA.

Background: Total body skin examinations (TBSE) are commonly performed in clinical practice. There is limited research on best practices for performing a TBSE.

Objective: To optimize the TBSE. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.02.028DOI Listing
February 2019

Measuring eating motives in older adults with and without functional impairments with The Eating Motivation Survey (TEMS).

Appetite 2019 Feb 15. Epub 2019 Feb 15.

Friedrich-Alexander-University of Erlangen-Nürnberg, Institute for Biomedicine of Aging, Kobergerstraße 60, 90408, Nürnberg, Germany.

Gaining a better understanding which motives play a role in daily eating is crucial in order to develop personalized interventions promoting adequate diet. The Eating Motivation Survey (TEMS) is a comprehensive tool to assess manifold reasons for eating but has not been specifically applied in an older sample including very old persons and persons differing in functional status. Therefore, the first step of the study was to investigate whether the basic motives of TEMS are consistent in an older sample and comparable across older adults with and without functional impairments. Read More

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http://dx.doi.org/10.1016/j.appet.2019.01.024DOI Listing
February 2019

Direct detection of Staphylococcus aureus in positive blood cultures through molecular beacon-based fluorescence in situ hybridization.

J Microbiol Methods 2019 Feb 15. Epub 2019 Feb 15.

Department of Clinical Laboratory, Hospital of Xinjiang Production and Construction Corps/Second Affiliated Hospital, Medical School of Shihezi University, Urumqi, Xinjiang, China. Electronic address:

Objective: Clinical diagnosis of bloodstream infection diseases depends on the blood culture results. Bacterial identification by traditional methods is time-consuming. This study aimed to utilize molecular beacon-based fluorescence in situ hybridization (MB-FISH) for rapid and direct detection of Staphylococcus aureus in positive blood cultures. Read More

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http://dx.doi.org/10.1016/j.mimet.2019.02.007DOI Listing
February 2019

Developability assessment of physicochemical properties and stability profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 envelope glycoprotein trimers as candidate vaccine antigens.

J Pharm Sci 2019 Feb 15. Epub 2019 Feb 15.

International AIDS Vaccine Initiative, New York, NY 10004 USA. Electronic address:

The induction of broadly neutralizing antibodies (bNAb) is a major goal in the development of an effective vaccine against HIV-1. A soluble, trimeric, germline (gI) bNAb-targeting variant of the HIV-1 envelope glycoprotein (termed BG505 SOSIP.v4. Read More

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http://dx.doi.org/10.1016/j.xphs.2019.01.033DOI Listing
February 2019

Neither Diplectanum nor specific: a dramatic twist to the taxonomic framework of Diplectanum (Monogenea: Diplectanidae).

Int J Parasitol 2019 Feb 15. Epub 2019 Feb 15.

Natural History Museum of Geneva, PO Box 6434, CH-1211 Geneva 6, Switzerland.

The taxonomy of the genus Diplectanum has been exclusively based on morphological features, with 28 nominal species parasitic on perciform fishes recognised. We used molecular data, to our knowledge for the first time, to evaluate the taxonomic framework of Diplectanum, infer the relationships amongst species attributed to this genus, re-assess the degree of host specificity and explore the population genetic structure of Diplectanum spp. parasitising Mediterranean sciaenids, which are potential target fish species for aquaculture diversification in the region. Read More

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http://dx.doi.org/10.1016/j.ijpara.2018.11.003DOI Listing
February 2019

Assemblies of lauryl maltose neopentyl glycol (LMNG) and LMNG-solubilized membrane proteins.

Biochim Biophys Acta Biomembr 2019 Feb 15. Epub 2019 Feb 15.

Univ. Grenoble Alpes, CNRS, CEA, Institute for Structural Biology (IBS), 38000 Grenoble, France. Electronic address:

Laurylmaltose neopentylglycol (LMNG) bears two linked hydrophobic chains of equal length and two hydrophilic maltoside groups. It arouses a strong interest in the field of membrane protein biochemistry, since it was shown to efficiently solubilize and stabilize membrane proteins often better than the commonly used dodecylmaltopyranoside (DDM), and to allow structure determination of some challenging membrane proteins. However, LMNG was described to form large micelles, which could be unfavorable for structural purposes. Read More

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http://dx.doi.org/10.1016/j.bbamem.2019.02.003DOI Listing
February 2019
3.836 Impact Factor

Pt Nanoparticles Loaded Graphene Aerogel Microspheres with Excellent Methanol Electrooxidation Performance.

Langmuir 2019 Feb 18. Epub 2019 Feb 18.

Platinum-decorated graphene aerogel microspheres were fabricated through a combined electrospraying, freeze-casting and solvothermal process. Platinum nanoparticles with a narrow size distribution are evenly anchored on the graphene aerogel microspheres without agglomeration benefitting from the distinct center-diverging microchannel structure of the graphene aerogel microspheres, which results in the as-prepared catalysts presenting excellent electrocatalytic performance including high electrocatalytic activity and high poison tolerance towards methanol electrooxidation, showing great potential for direct methanol fuel cell anode catalysts. In particular, the Platinum-decorated graphene aerogel microspheres exhibits an extremely high mass activity of 1098. Read More

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http://dx.doi.org/10.1021/acs.langmuir.9b00021DOI Listing
February 2019

Hydrogen-Bonded Polyrotaxane Cation Structure in Nickel Dithiolate Anion Radical Salts, Ferromagnetic and Semiconducting Behavior Associated with Structural Phase Transition.

Chemistry 2019 Feb 18. Epub 2019 Feb 18.

Hokkaido University, Research Institute for Electronic Science, N20W10, Kita-ku, 001-0020, Sapporo, JAPAN.

The pseudo-polyrotaxane structure of [(H-bpy+)(DB[24]crown-8)]∞ (H-bpy+ = monoprotonated 4,4-bipyridinium; DB[24]crown-8 = dibenzo[24]crown-8) was incorporated into anion radical salts, [Ni(dmit)2]- (dmit2- = 1,3-dithio-2-thione-4,5-dithiolate). (H-bpy+)(DB[24]crown-8)[Ni(dmit)2]- crystallized into two polymorphs: crystals 1 and 2. Crystal 1 had a lower density and looser packing structure. Read More

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http://dx.doi.org/10.1002/chem.201806230DOI Listing
February 2019

Appraisement of crystal expansion in CH3NH3PbI3 on doping: improved photovoltaics properties.

ChemSusChem 2019 Feb 18. Epub 2019 Feb 18.

SWITZERLAND.

Three-dimensional hybrid perovskite materials (CH3NH3PbI3) suffer from intrinsic instability due to organic cation evaporation and ion migration. The inclusion of a large organic cation such as guanidinium has been probed to stabilize the structure. In this work, we put forward the inclusion of imidazolium iodide (C3N2H5I) as organic cation inside the CH3NH3PbI3 matrix, as a reservoir to control the spontaneous loss of iodide. Read More

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http://dx.doi.org/10.1002/cssc.201803043DOI Listing
February 2019

[Use of virtual reality for neurodevelopmental disorders. A review of the state of the art and future agenda].

Medicina (B Aires) 2019 ;79 Suppl 1:77-81

Centro de Desarrollo Cognitivo Red Cenit, Valencia, España.

To date, the diagnostic tools for autism spectrum disorder (ASD) have been mostly based on qualitative criteria from observational information in contexts with low ecological validity. We are witnessing a growing scientific activity that proposes the use of implicit measures for the evaluation and diagnosis of ASD. These measures are based on processes of a biological and unconscious nature, underlying the capacity of human cognition, and are obtained through the acquisition and treatment of brain, physiological and behavioral responses in order to obtain the behavioral structure of the ASD patient facing a stimulus. Read More

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January 2019

Clustering tennis players' anthropometric and individual features helps to reveal performance fingerprints.

Eur J Sport Sci 2019 Feb 18:1-13. Epub 2019 Feb 18.

c Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), CreativeLab Research Community , Universidade de Trás-os-Montes e Alto Douro , Vila Real , Portugal.

The study was aimed to explore distinct players' groups according to their anthropometric and individual features, and to identify the key performance indicators that discriminate player groups. Match statistics, anthropometric and personal features of 1188 male players competing during 2015-2017 main draw Grand Slam singles events were collected. Height, weight, experience, handedness and backhand style were used to automatically classify players into different clusters through unsupervised learning model. Read More

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http://dx.doi.org/10.1080/17461391.2019.1577494DOI Listing
February 2019

In Situ Measure of Intrinsic Bond Strength in Crystalline Structures: Local Vibrational Mode Theory for Periodic Systems.

J Chem Theory Comput 2019 Feb 18. Epub 2019 Feb 18.

The local vibrational mode analysis developed by Konkoli and Cremer has been successfully applied to characterize the intrinsic bond strength via local bond stretching force constants in molecular systems. A wealth of new insights into covalent bonding and weak chemical interactions ranging from hydrogen, halogen, pnicogen, chalcogen to tetrel bonding has been obtained. In this work we extend the local vibrational mode analysis to periodic systems, i. Read More

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http://dx.doi.org/10.1021/acs.jctc.8b01279DOI Listing
February 2019

Predicting Activity Cliffs with Free Energy Perturbation.

J Chem Theory Comput 2019 Feb 18. Epub 2019 Feb 18.

Activity cliffs (ACs) are an important type of structure-activity relationship in medicinal chemistry where small structural changes result in unexpectedly large changes in biological activity. Being able to predict these changes would have a profound impact on lead optimization of drug candidates. Free energy perturbation is an ideal tool for predicting relative binding energy differences for small structural changes but its performance for ACs is unknown. Read More

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http://dx.doi.org/10.1021/acs.jctc.8b01290DOI Listing
February 2019

Phenology of Phytoplankton Blooms in a Trophic Lake Observed from Long-Term MODIS Data.

Environ Sci Technol 2019 Feb 18. Epub 2019 Feb 18.

Phytoplankton phenology critically affects elements biogeochemical cycles, ecosystem structure, and productivity. However, our understanding about the phenological process and driving mechanism is still very limited due to the shortage of long-term observation data. We used all available daily MODIS-Aqua data from 2003 to 2017 to determine bloom start dates (BSDs) in a typical trophic lake (Lake Taihu) and investigate how phytoplankton BSDs respond to climate change and environmental factors. Read More

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http://dx.doi.org/10.1021/acs.est.8b06887DOI Listing
February 2019

Design and Construction of a Chiral Cd(II)-MOF from Achiral Precursors: Synthesis, Crystal Structure and Catalytic Activity toward C-C and C-N Bond Forming Reactions.

Inorg Chem 2019 Feb 18. Epub 2019 Feb 18.

Department of Chemical Sciences , Indian Institute of Science Education and Research Mohali , Sector 81, Manauli PO, S.A.S. Nagar, Mohali , Punjab 140306 , India.

Using achiral components, a V-shaped dicarboxylic acid (HL) and a conformationally flexible bidentate linker (bpp), a thermally stable chiral metal organic framework {[Cd(bpp)(L)(HO)]·DMF} (1), where HL = 4,4'-(dimethylsilanediyl)bis-benzoic acid, bpp = 1,3-bis(4-pyridyl)propane and DMF = N,N-dimethylformamide, has been solvothermally synthesized and crystallographically characterized. It consists of 1D helical chains linked at the cadmium centers resulting in an overall 2D framework. Its microporous nature was confirmed by gas-sorption measurements. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.8b03307DOI Listing
February 2019

[Immunoassay and discriminant analysis to improve the diagnosis of ovarian cancer in the elderly.]

Klin Lab Diagn 2018 ;63(11):707-710

FGBOU VO Kursk State Medical University, 305041, Kursk, Russia.

Ovarian cancer is a common pathology in the structure of tumors among elderly women. The aim of the work is to identify the leading indicators of interleukin profile to improve the diagnosis of ovarian cancer in the elderly. Enzyme immunoassay studied serum levels of interleukins in 78 patients with ovarian cancer stage IIB-IIIB according to the classification of FIGO at the age of 65-70 years and 42 women of similar age without ovarian cancer at the time of the study and in history. Read More

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http://dx.doi.org/10.18821/0869-2084-2018-63-11-707-710DOI Listing
January 2018
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