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BMC Infect Dis 2020 Jul 2;20(1):470. Epub 2020 Jul 2.

Department of Hematology and Rheumatology, Kindai University School of Medicine, 377-2 Oonohigashi, Osaka-Sayama, Osaka, 589-0014, Japan.

Background: Strongyloidiasis is a gastrointestinal parasitic infection caused by percutaneous infection with Strongyloides stercoralis. Digestive symptoms such as diarrhea and abdominal pain are the main manifestation, but serious infections such as septicemia, purulent meningitis, and bacterial pneumonia may occur in individuals harboring human T-lymphotropic virus type 1 (HTLV-1) or who are immunocompromised. Although coinfection with Strongyloides stercoralis and HTLV-1 can lead to chronic strongyloidiasis and a disseminated form of the disease, there is a high rate of response to the anthelmintic ivermectin. Read More

Pathogens 2020 Jun 24;9(6). Epub 2020 Jun 24.

Clinica Medicine Department, University Miguel Hernández de Elche, 03550 Sant Joan d'Alacant, Alicante, Spain.

infection is frequently underdiagnosed since many infections remain asymptomatic.

Aim: To estimate the prevalence and characteristics of asymptomatic infection in Latin American migrants attending a community-based screening program for Chagas disease in Spain.

Methodology: Three community-based Chagas disease screening campaigns were performed in Alicante (Spain) in 2016, 2017, and 2018. Read More

Infect Dis (Auckl) 2020 15;13:1178633720932544. Epub 2020 Jun 15.

Mundo Sano Foundation, Institute of Health Carlos III, Madrid, Spain.

Background: Ivermectin has been proven to be highly effective against in some countries. However, its single dose (200 μg/kg) efficacy has not been proven up until now in Ethiopia.

Objective: This study aimed to evaluate the efficacy of single dose ivermectin against infection among school children. Read More

Am J Trop Med Hyg 2020 Jun 22. Epub 2020 Jun 22.

Department of Infection and Host Defense, Graduate School of Medicine, Chiba University, Chiba, Japan.

We reported 865 cases of soil-transmitted nematodiasis occurring in Japan during 2000-2017. The predominant nematode was ( = 279, 32.3% of all cases), and other species included (30. Read More

Pathogens 2020 Jun 23;9(6). Epub 2020 Jun 23.

Barcelona Institute for Global Health, ISGlobal-Hospital Clinic, Universitat de Barcelona, 08036 Barcelona, Spain.

is a widely distributed nematode more frequent in tropical areas and particularly severe in immunosuppressed patients. The aim of this study was to determine factors associated with strongyloidiasis in migrants living in a non-endemic area and to assess the response to treatment and follow-up in those diagnosed with the infection. We performed a multicenter case-control study with 158 cases and 294 controls matched 1:2 by a department service. Read More

Dis Markers 2020 31;2020:5265198. Epub 2020 May 31.

Infectious and Tropical Diseases Research Group (e-INTRO), Biomedical Research Institute of Salamanca-Research Centre for Tropical Diseases at the University of Salamanca (IBSAL-CIETUS), Faculty of Pharmacy, University of Salamanca, Salamanca 37007, Spain.

Human strongyloidiasis a soil-transmitted infection caused by is one of the most neglected amongst the so-called Neglected Tropical Diseases (NTDs). is a nematode, which is distributed worldwide; it has been estimated that it could affect millions of people, mainly in tropical and subtropical endemic regions. The difficulties of diagnosis lead to infection rates being underreported. Read More

Interdiscip Perspect Infect Dis 2020 26;2020:8649409. Epub 2020 May 26.

Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: has the ability to proliferate in its hosts for a long time. In most patients with a competent immune system, the infection remains asymptomatic.

Objectives: Herein, we report a case of concomitant infection of and . Read More

Pathogens 2020 Jun 13;9(6). Epub 2020 Jun 13.

Department of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, 37024 Verona, Italy.

Strongyloidiasis is a common neglected tropical disease in tropical and sub-tropical climatic zones. At the worldwide level, there is high uncertainty about the strongyloidiasis burden. This uncertainty represents an important knowledge gap since it affects the planning of interventions to reduce the burden of strongyloidiasis in endemic countries. Read More

Pathogens 2020 Jun 3;9(6). Epub 2020 Jun 3.

Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.

Autochthonous human and canine strongyloidiasis is reported in Europe but is unclear whether the transmission of infection still occurs. We report a previously unpublished human case in an Italian teen and perform a systematic review of literature on autochthonous human and canine strongyloidiasis in Europe to investigate the current dynamic of transmission. Overall, 109 papers published after 1987 were included and one previously unpublished Italian case was added. Read More

Parasitol Int 2020 Jun 3;78:102151. Epub 2020 Jun 3.

Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan. Electronic address:

Strongyloides stercoralis is a parasitic nematode and a major pathogen responsible for human strongyloidiasis. The presence of this species in the dog population has led to an interest in studying the phylogenetic relationships among Strongyloides spp. in carnivore hosts. Read More

Open Forum Infect Dis 2020 May 12;7(5):ofaa155. Epub 2020 May 12.

Instituto de Medicina Tropical "Alexander von Humboldt," Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: Endemic regions of cutaneous leishmaniasis (CL) and intestinal helminthiasis overlap. CL treatment with systemic pentavalent antimonial drugs (Sb) fails in 10%-30% of patients. The study objective was to assess the etiological role of intestinal helminthiasis in CL treatment failure. Read More

Biomedica 2020 05 1;40(Supl. 1):32-36. Epub 2020 May 1.

Escuela de Medicina, Universidad del Valle, Cali, Colombia.

Strongyloides stercoralis hyperinfection syndrome is a medical emergency that requires a high level of suspicion. Immunocompromised patients are at high risk of hyperinfection syndrome; however, malnutrition, alcoholism, and diabetes mellitus also need to be considered as predisposing factors. The diagnosis and treatment of Strongyloides hyperinfection are challenging and patients often have severe complications. Read More

BMJ Glob Health 2020 May;5(5)

Instituto de Salud Global Barcelona, Barcelona, Spain.

Background: The best strategy for controlling morbidity due to imported strongyloidiasis in migrants is unclear. We evaluate the cost-effectiveness of six possible interventions.

Methods: We developed a stochastic Markov chain model. Read More

Assist Inferm Ric 2020 Jan-Mar;39(1):47-56

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Introduction: Against the increasing recognition of the critical importance of a direct participation of community members to assure effective health care in peripheral areas of Middle and Low Income Countries (MLIC), representative field experiences of their essential role are only occasionally available.

Aims And Methods: We report a narrative, factual documentation of a spectrum of projects covering the basic and specific health needs of the disperse communities in Ecuador, a model MLIC, and discuss the broader implications of the role and performance of HPs over a long period, 1980-2018, in the project activation, implementation and monitoring. Read More

PLoS Negl Trop Dis 2020 05 26;14(5):e0008187. Epub 2020 May 26.

IRCCS Sacro Cuore Don Calabria Hospital, Center for Tropical Diseases, Negrar, Verona, Italy.

Loiasis, caused by the filarial nematode Loa loa, is endemic in Central and West Africa where about 10 million people are infected. There is a scarcity of convenient, commercial diagnostics for L. loa. Read More

Pathogens 2020 May 18;9(5). Epub 2020 May 18.

Institute of Tropical Medicine, Department of Clinical Sciences, 2000 Antwerp, Belgium.

Background: a nematode endemic in all (sub)tropical regions, can cause life-threatening disease, especially in immunosuppressed patients. Many countries with high HIV-prevalence rates are also highly endemic, and co-infection may occur.

Methods: Retrospective study based on serological testing for in all HIV-infected migrants followed at the Institute of Tropical Medicine, Antwerp, Belgium. Read More

Clin Infect Dis 2020 May 18. Epub 2020 May 18.

Laboratory of Emerging Infectious Diseases, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.

Indian J Surg 2020 May 12:1-5. Epub 2020 May 12.

Department of General Surgery, Narayana Medical College, Chinthareddy Palem, Nellore, Andhra Pradesh 524003 India.

is a helminth, widely distributed in tropical and subtropical countries. Its infestation in humans usually does not produce symptoms. However, in some patients, severe and life-threatening forms of this infection can occur, especially in immunocompromised individuals. Read More

Infection 2020 May 16. Epub 2020 May 16.

Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.

Purpose: To analyze epidemiology and burden of Neglected Tropical Diseases (NTDs) in Italy.

Methods: We used Hospital Discharge Records and number of residents in Italy to calculate number and rate of hospitalization for Chagas disease, dengue, filariasis, leishmaniasis, schistosomiasis, strongyloidiasis, Taenia solium taeniasis, and cysticercosis by sex, citizenship group, and region in the period 2011-2016.

Results: 7195 hospitalizations for NTDs were retrieved, accounting for 7375 diagnoses, 60% in Italians and 40% in foreigners. Read More

Parasit Vectors 2020 May 13;13(1):250. Epub 2020 May 13.

Department of Integrative Evolutionary Biology, Max Planck Institute for Developmental Biology, Tübingen, Baden-Württemberg, Germany.

Background: Strongyloidiasis is a soil borne helminthiasis, which in most cases is caused by Strongyloides stercoralis. Human infections with S. fuelleborni fuelleborni and S. Read More

Rev Inst Med Trop Sao Paulo 2020 11;62:e23. Epub 2020 May 11.

Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

In experimental infection with Strongyloides venezuelensis, the acute and recovery phases can be distinguished, unlike human infections caused by Strongyloides stercoralis. The objective of this study was to evaluate the production of anti-Strongyloides IgG antibodies and the recognition of immunogenic protein bands during the acute and the recovery phases in rats experimentally infected with S. venezuelensis. Read More

PLoS Negl Trop Dis 2020 05 13;14(5):e0008232. Epub 2020 May 13.

Centre for Chronic Disease Prevention, James Cook University, Cairns, Queensland, Australia.

Background: The life-threatening clinical manifestations of strongyloidiasis are preventable with early detection and effective treatment. The aim of this study was to assess if there was an increase to the number and proportion of persons tested for chronic strongyloidiasis, as a result of integrating Strongyloides stercoralis serology into the existing preventive health assessment system in four Aboriginal health services in endemic communities.

Methodology: A prospective, longitudinal, before-and-after intervention study was conducted in four Aboriginal health services in remote endemically infected communities in the Northern Territory, Australia, from July 2012 to December 2016. Read More

Pathogens 2020 May 4;9(5). Epub 2020 May 4.

Servicio de Enfermedades Infecciosas y Medicina Tropical, Hospital Regional de Loreto, 16001 Iquitos, Peru.

Strongyloidiasis is a soil-transmitted helminthiasis with a high global prevalence.

Objectives: We aimed to evaluate the prevalence of infection and assess strongyloidiasis serology as a screening technique in the Peruvian Amazon.

Material And Methods: We performed a cross-sectional study of strongyloidiasis in 300 pregnant women in Iquitos (Peru) from 1 May 2019 to 15 June 2019. Read More

Intern Med J 2020 May 5. Epub 2020 May 5.

Menzies School of Health Research, Charles Darwin University.

Background: Strongyloides stercoralis is a soil-transmitted helminth, endemic in remote Aboriginal and Torres Strait Islander communities in northern Australia with estimates of prevalences up to 60%. Hyperinfection in the setting of immunosuppression is a rare but well-recognised cause of significant morbidity and mortality. However, the morbidity associated with chronic uncomplicated infection is less well characterised. Read More

J Family Med Prim Care 2020 Feb 28;9(2):485-491. Epub 2020 Feb 28.

Department of Microbiology, All India Institute of Microbiology, Rishikesh, Uttarakhand, India.

Strongyloidiasis is frequently asymptomatic but can cause disseminated disease and variable presentations. Diagnosis is often delayed or misdirected either due to poor degree of clinical suspicion or clinical imitation of other gastrointestinal conditions. This infection is not infrequent and several cases from all over India have been reported barring few states from central India. Read More

Mo Med 2020 Mar-Apr;117(2):89-94

Christian Rojas-Moreno, MD, William Salzer, MD, and Gordon Christensen, MD is in the Department of Medicine, Division of Infectious Diseases, University of Missouri, Columbia, Missouri.

Background: There is lack of specific data on imported infections in the mid-west United States (U.S.). Read More

Best Pract Res Clin Rheumatol 2020 Apr 13:101509. Epub 2020 Apr 13.

Programa de Pós-graduação em Ciências Médicas, Programa de Pós-Graduação em Medicina Tropical, SGAN 605. Av. L2 Norte, CEP: 70910-900, Brasília, Distrito Federal, Brazil. Electronic address:

Autoimmune and autoinflammatory diseases are associated with severe morbidity, and represent an impactful health and economic burden worldwide. The treatment of these diseases can include a course with detrimental side effects. Immunosuppression increases the risk of opportunistic infections, but in some cases, the abrupt discontinuation of these medications can result in immune reconstitution inflammatory syndrome. Read More

PLoS Negl Trop Dis 2020 04 13;14(4):e0008184. Epub 2020 Apr 13.

Universidad Nacional de Salta, Instituto de Investigaciones de Enfermedades Tropicales/CONICET, Orán, Salta, Argentina.

Trial Registration: PROSPERO (registration code CRD42019131127). Read More

Future Microbiol 2020 Apr 6;15:437-444. Epub 2020 Apr 6.

National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, IRYCIS, Ctra Colmenar, Km 9100, 28034 Madrid, Spain.

Helminth infections cause considerable morbidity worldwide and may be frequently underdiagnosed especially in areas of lower endemicity. Patients may harbor latent infections that may become symptomatic years or decades after the initial exposure and timely diagnosis may be critical to prevent complications and improve outcomes. In this context, disease in special populations, such as immunosuppressed patients, may be of particular concern. Read More

PLoS Med 2020 03 31;17(3):e1003083. Epub 2020 Mar 31.

Centers for Disease Control and Prevention, Division of Global Migration and Quarantine, Immigrant, Refugee, and Migrant Health Branch, Atlanta, Georgia, United States of America.

Background: Since 2008, the United States has issued between 2,000 and 19,000 Special Immigrant Visas (SIV) annually, with the majority issued to applicants from Iraq and Afghanistan. SIV holders (SIVH) are applicants who were employed by, or on behalf of, the US government or the US military. There is limited information about health conditions in SIV populations to help guide US clinicians caring for SIVH. Read More

Am J Trop Med Hyg 2020 Jun;102(6):1396-1398

Division of Infectious Diseases, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Strongyloidiasis is a disease caused by the parasite in humans. We present a case of incidentally discovered urinary tract infection in a patient in whom there was a urologic surgery consisting of urinary diversion created by self-bowel transplantation and conduit creation. Historical review demonstrated eosinophilia before surgery and detection of the parasite. Read More

Am J Trop Med Hyg 2020 Jun;102(6):1386-1395

Department of Pediatrics: Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas.

Strongyloidiasis affects an estimated hundreds of millions of people worldwide, with infection possibly persisting for life without appropriate therapy because of the helminth's unique autoinfection cycle. Like other soil-transmitted helminths, because of the environmental conditions required for the life cycle of , this parasite is endemic to tropical, subtropical, and temperate countries and areas with inadequate sanitation infrastructure. Given continued poverty and that nearly one in five American homes are lacking proper sanitation systems, many U. Read More

Indian J Public Health 2020 Jan-Mar;64(1):90-92

Clinical Microbiologist, Department of Laboratory Medicine, MIOT International, Chennai, Tamil Nadu, India.

Strongyloides stercoralis is unique among the nematodes, in which it completes its life cycle inside a single human host by causing autoinfection in the host, and it causes hyperinfection leading to persistent and fatal disseminated infections in immunocompromised hosts. The present case report is about strongyloidiasis fatal hyperinfection in a patient with malignant tumor of the tongue on radiotherapy treatment, to highlight the need for clinical suspicion of strongyloidiasis in an immunocompromised host. As per the Centers for Disease Control and Prevention, the mortality in strongyloides hyperinfection syndrome is alarmingly high, a case fatality rate that is almost 90%. Read More

Lupus 2020 05 17;29(6):539-546. Epub 2020 Mar 17.

Division of Clinical Microbiology, Department of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.

Background: Strongyloidiasis can be fatal in systemic lupus erythematosus (SLE) patients, but few epidemiological studies have investigated the burden of this tropical disease among the SLE population. This study aimed to assess the prevalence and associated factors of strongyloidiasis among SLE patients in Southern Thailand.

Methods: A cross-sectional study was conducted on 180 SLE patients attending the Rheumatology Clinic at Songklanagarind Hospital. Read More

Clin Infect Dis 2020 Mar 10. Epub 2020 Mar 10.

Department of Medicine, Sections of Infectious Diseases, Baylor College of Medicine, Houston TX, USA.

Background: Strongyloidiasis can cause devastating morbidity and death in immunosuppressed patients. Identification of reliable biomarkers for strongyloidiasis in immunosuppressed patients is critical for the prevention of severe disease.

Methods: In this cross-sectional study of solid organ transplant (SOT) candidates and recipients, we quantified Strongyloides-specific IgG to the recombinant NIE and/or to a soluble extract of S. Read More

Int J STD AIDS 2020 Apr 4;31(5):398-401. Epub 2020 Mar 4.

Imperial College Healthcare NHS Trust, London, UK.

PLoS Negl Trop Dis 2020 03 3;14(3):e0008101. Epub 2020 Mar 3.

National Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.

Background: The prevalence of helminth infections exhibits an inverse association with the prevalence of Type 2 diabetes mellitus (T2DM), and helminths are postulated to mediate a protective effect against T2DM. However, the biological mechanism behind this effect is not known.

Aims/methods: We postulated that helminth infections act by modulating the pro-inflammatory cytokine and chemokine milieu that is characteristic of T2DM. Read More

Parasitol Int 2020 Jun 29;76:102092. Epub 2020 Feb 29.

Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru; Infectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555-0435, USA. Electronic address:

Background: Regulatory T-cells (Tregs) are increased in patients with HTLV-1/Strongyloides stercoralis co-infection, and they may modify otherwise protective antigen-specific cytokine production. We hypothesized that effective anti-helminthic treatment would decrease Tregs and restore antigen-specific cytokine responses.

Methods/results: We enrolled 19 patients with Strongyloides larvae in their stool by Baerman's test. Read More

Emerg Infect Dis 2020 Mar;26(3):401-408

Clinical characteristics of disseminated strongyloidiasis, the severest form of strongyloidiasis, are not well described. We conducted a retrospective, consecutive chart review of patients with disseminated strongyloidiasis admitted to Okinawa Chubu Hospital in Okinawa, Japan, during January 1975-December 2017. The 70 patients were classified into 3 clinical phenotypes: dissemination (32 patients [45. Read More

Parasitol Int 2020 Jun 20;76:102087. Epub 2020 Feb 20.

Institute of Pathology, Technical University Munich, Munich, Germany.

We report a case of a fatal Strongyloides stercoralis hyperinfection syndrome (SHS) in a migrant from Kenya, who had been living in Germany for three decades. A short-course oral steroid treatment for Chronic Obstructive Pulmonary Disease (COPD) exacerbation had been administered four weeks prior to the presentation. The initial clinical and radiological findings suggested a mechanical small bowel obstruction as a cause of ileus. Read More

Parasitol Res 2020 Apr 21;119(4):1409-1413. Epub 2020 Feb 21.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

We aimed to compare the efficacy of modified agar plate fecal culture (mAPC) and standard agar plate culture (sAPC) for diagnosis of Strongyloides stercoralis infection in a community at Khon Kaen Province, Thailand. Fecal samples were collected from participants individually (n = 1076) and were tested using these two methods. Modified APC and sAPC detected 129 (11. Read More

Cureus 2020 Jan 8;12(1):e6603. Epub 2020 Jan 8.

Gastroenterology, Gastroenterology Associates of Brooklyn, Brooklyn, USA.

Strongyloides is a unique nematode in its ability to cause a secondary hyperinfection and disseminated disease several years following initial contact. The prevalence of Strongyloides infection has been rising; it is currently considered a global disease, which presents with a broad spectrum of clinical signs and symptoms among patients. This case report focuses on a 67-year-old Caribbean female presenting with severe weight loss, vomiting, early satiety, and mild anemia who was subsequently diagnosed with strongyloidiasis on the basis of a duodenal biopsy pathology report obtained via esophagogastroduodenoscopy (EGD). Read More

Pathogens 2020 Feb 11;9(2). Epub 2020 Feb 11.

Barcelona Institute for Global Health, ISGlobal-Hospital Clinic, Universitat de Barcelona, 08036 Barcelona, Spain.

: Strongyloidiasis is a prevailing helminth infection ubiquitous in tropical and subtropical areas, however, seroprevalence data are scarce in migrant populations, particularly for those coming for Asia. : This study aims at evaluating the prevalence of at the hospital level in migrant populations or long term travellers being attended in out-patient and in-patient units as part of a systematic screening implemented in six Spanish hospitals. A cross-sectional study was conducted and systematic screening for infection using serological tests was offered to all eligible participants. Read More

Trans R Soc Trop Med Hyg 2020 Jun;114(6):459-469

Department of Mycology and Parasitology, School of Medicine, Babol University of Medical Sciences, Ganj Afrooz Ave., Babol 47176-47745, I.R. Iran.

The standard method for the diagnosis of Strongyloides stercoralis, stool examinations, is inconvenient and, therefore, serological methods have been proposed. This study aimed to evaluate the accuracy of serological assays for the diagnosis of strongyloidiasis using a systematic review and meta-analysis model. Four electronic databases were reviewed. Read More

Pathogens 2020 Feb 6;9(2). Epub 2020 Feb 6.

Hospital for Tropical Diseases, University College London Hospitals, London WC1E 6JB, UK.

Gastrointestinal (GI) symptoms are a frequent reason for primary care consultation, and common amongst patients with strongyloidiasis. We conducted a prospective cohort and nested case control study in East London to examine the predictive value of a raised eosinophil count or of GI symptoms, for infection in South Asian migrants. We included 503 patients in the final analyses and all underwent a standardised GI symptom questionnaire, eosinophil count and serology testing. Read More

IDCases 2020 16;19:e00703. Epub 2020 Jan 16.

Department of Intensive Care Unit, Centro Hospitalar Porto, Porto, Portugal.

is a nematode, endemic in tropical and subtropical areas. Strongyloidiasis has been reported in recipients of hematopoietic stem cells, kidney, liver, heart, intestine, and pancreas, eventually presenting as disseminated strongyloidiasis and hyperinfection syndrome (SHS) which is associated with high mortality. We report one case of a recent renal transplant recipient, who presented with gastrointestinal and respiratory symptoms, evolving into shock. Read More

Parasitol Res 2020 Mar 1;119(3):1139-1148. Epub 2020 Feb 1.

Department of Medicine, Division of Infectious Diseases, Immunology, and International Medicine, University of Illinois at Chicago, 808 South Wood, M/C 735, Chicago, IL, 60612, USA.

Parasitic infections are likely under-recognized among immigrant populations in the USA. We conducted a cross-sectional study to evaluate if such infections have health impacts among recent immigrants in Chicago and to identify predictive factors for parasitic infections. A total of 133 recent immigrants were enrolled, filling out a standardized medical questionnaire and providing blood and stool samples. Read More

Vet Parasitol 2020 Feb 22;278:109037. Epub 2020 Jan 22.

Department of Parasitology, Biological Science Institute of the Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. Electronic address:

Species of Strongyloides infect a wide range of hosts worldwide. Due to their complex life cycle, it is hard to control the transmission of these parasites. Several species show evidence of vertical transmission; however, the impact of this transmission route on the susceptibility of the offspring has been poorly investigated. Read More

PLoS Negl Trop Dis 2020 01 31;14(1):e0007998. Epub 2020 Jan 31.

Infectious Diseases Unit, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: Severe Strongyloides stercoralis infection in kidney transplant recipients is associated with considerable morbidity and mortality, although little is known about the risk factors for such infection.

Methodology/principal Findings: This was a retrospective, multicenter, case-control study in which we assessed the risk factors for and clinical outcomes of severe S. stercoralis infections in kidney transplant recipients in Brazil. Read More

BMC Infect Dis 2020 Jan 28;20(1):76. Epub 2020 Jan 28.

Department of Medicine, The University of Calgary, Calgary, Alberta, Canada.

Background: Following migration from Schistosoma and Strongyloides endemic to non-endemic regions, people remain at high risk for adverse sequelae from these chronic infections. HIV co-infected persons are particularly vulnerable to the serious and potentially fatal consequences of untreated helminth infection. While general screening guidelines exist for parasitic infection screening in immigrant populations, they remain silent on HIV positive populations. Read More