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3,943 results match your criteria Strongyloidiasis


Seroepidemiological aspects of human infection by Strongyloides stercoralis in Alfenas, southern Minas Gerais, Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):855-859

Laboratório de Diagnóstico de Parasitoses, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.

Introduction: In most Strongyloides stercoralis infected individuals, nematoidosis occurs asymptomatically, but in immunocompromised patients, it can cause hyperinfection. Serological techniques seem to be a good alternative for detecting this parasite.

Methods: The frequency of seropositivity for strongyloidiasis in Alfenas, MG, was estimated using the enzyme linked immunosorbent assay on blood samples, between May and August of 2015. Read More

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Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome.

Case Rep Infect Dis 2018 28;2018:6870768. Epub 2018 Oct 28.

Department of Medicine, Poona Hospital and Research Center, Pune, Maharashtra, India.

Parasitic infections such as and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease. Read More

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October 2018
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High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study.

PLoS Negl Trop Dis 2018 Nov 29;12(11):e0007010. Epub 2018 Nov 29.

ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.

Background: Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, using our institution's serum bank. Read More

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November 2018

Gastroduodenal involvement in disseminated strongyloidiasis.

JGH Open 2018 Apr 22;2(2):75-76. Epub 2018 Feb 22.

Department of Gastroenterology Kobe City Medical Center General Hospital Kobe Japan.

Here, we report the case of a 57-year-old Peruvian man on long-term corticosteroid therapy for a drug allergy and proton pump inhibitors for chronic dyspepsia symptoms. Upper gastrointestinal endoscopy showed multiple white granular lesions and widespread erosions in the stomach. Our findings indicate that gastric strongyloidiasis should be carefully considered in high-risk patients even if endoscopic findings are nonspecific. Read More

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Serodiagnosis and early detection of Strongyloides stercoralis infection.

J Microbiol Immunol Infect 2018 Oct 11. Epub 2018 Oct 11.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia. Electronic address:

Strongyloidiasis is a major neglected tropical disease with the potential of causing lifelong infection and mortality. One of the ways for effective control of this disease is developing improved diagnostics, particularly using serological approaches. A serological test can achieve high diagnostic sensitivity and specificity, has the potential for point-of-care translation, and can be used as a screening tool for early detection. Read More

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October 2018

Efficacy of ivermectin to control Strongyloides stercoralis infection in sheltered dogs.

Acta Trop 2018 Nov 19;190:204-209. Epub 2018 Nov 19.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy; Dipartimento di Diagnostica e Sanità pubblica, Università degli Studi di Verona, Italy.

In dogs, information on treatments against S. stercoralis infection is rare and anecdotal. The aim of the present work was to evaluate the treatment outcome of S. Read More

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November 2018
9 Reads

Strongyloidiasis and Culture-Negative Suppurative Meningitis, Japan, 1993-2015.

Emerg Infect Dis 2018 Dec;24(12):2378-2380

Community-acquired Enterobacteriaceae infection and culture-negative meningitis are rare and atypical subtypes of meningitis in adults. Of 37 patients who had atypical suppurative meningitis during 1993-2015 in Okinawa, Japan, 54.5% had strongyloidiasis, of which 9. Read More

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December 2018
1 Read

Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem.

Am J Trop Med Hyg 2018 Nov 19. Epub 2018 Nov 19.

Division of Neurology, St. Joseph's Health Centre, Toronto, Canada.

Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the CNS sample in one case. Read More

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November 2018
13 Reads

Fatal strongyloidiasis after corticosteroid therapy for presumed chronic obstructive pulmonary disease.

JMM Case Rep 2018 Sep 11;5(9):e005165. Epub 2018 Sep 11.

Sumeru Hospital, Dhapakhel, Lalitpur, Nepal.

Introduction: Strongyloidiasis is a neglected tropical disease with global prevalence. Under some cases of immune suppression (especially with corticosteroid administration), the nematode involved disseminates, leading to an amplified, possibly lethal hyper-infection syndrome.

Case Presentation: A 56-year-old Nepalese man presenting with chief complaints of nausea, vomiting, joint pain and abdominal cramps was admitted to Sumeru Hospital. Read More

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September 2018
4 Reads

Accuracy of Urine and Serum Assays for the Diagnosis of Strongyloidiasis by Three Enzyme-Linked Immunosorbent Assay Protocols.

Am J Trop Med Hyg 2018 Nov 5. Epub 2018 Nov 5.

Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand.

To evaluate the accuracy and reliability of urine assay for the diagnosis of strongyloidiasis, three different immunoassays were used to assess the diagnostic accuracy of anti- IgG in urine and compared with those in serum samples. Analyses by InBios enzyme-linked immunosorbent assay (ELISA) kit (NIE recombinant antigen), SciMedx ELISA kit ( antigen), and our in-house ELISA ( antigen) yielded comparable diagnostic performances between urine and serum assays. Levels of -specific IgG in urine significantly correlated with those in serum. Read More

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November 2018
4 Reads

Hypermetabolic Diffuse Proximal Small Bowel Wall Thickening on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography? Consider Strongyloidiasis among the Differentials.

Indian J Nucl Med 2018 Oct-Dec;33(4):368-369

Department of Nuclear Medicine, MIOT International, Chennai, Tamil Nadu, India.

Strongyloidiasis is an emerging tropical/subtropical parasitic infection commonly encountered in immunocompromised patients and often accompanied by life-threatening gram-negative bacteremia. We presented an interesting image of a critically ill 66-year-old lady, an asthmatic on high dose steroids, presenting with unexplained fever and vomiting where fluorodeoxyglucose positron emission tomography/computed tomography and endoscopic biopsy revealed this often neglected pathogenic nematode. Read More

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November 2018
1 Read

Severe strongyloidiasis and systemic vasculitis: comorbidity, association or both? Case-based review.

Rheumatol Int 2018 Dec 23;38(12):2315-2321. Epub 2018 Oct 23.

Clinic of Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia.

A possible association between strongyloidiasis and systemic vasculitis is rarely reported in the literature. We report the case of a patient with severe strongyloidiasis and an angiographic finding consistent with polyarteritis nodosa. Diagnosis of strongyloidiasis was made by finding of larvae and adult parasites in samples of the upper gastrointestinal tract mucosa and stool. Read More

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December 2018
8 Reads

[Severe infection: a case report].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Sep;30(4):479-480

Department of Laboratory Medicine, Fujian Provincial Hospital, Fuzhou 350001, China.

This paper reports a severe case of infection during routine sputum smear examinations, due to cough and shortness of breath, so as to improve clinicians' awareness of strongyloidiasis to avoid and reduce misdiagnosis and missed diagnosis. Read More

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September 2018
1 Read

Parasitic Infections Associated with Unfavourable Outcomes in Transplant Recipients.

Medicina (Kaunas) 2018 May 1;54(2). Epub 2018 May 1.

Department of Nephrology, Transplantology and Internal Diseases, Medical University of Gdansk, 80⁻210 Gdansk, Poland.

. The immunosuppression used after transplantation (Tx) is associated with an increased risk of opportunistic infections. In Europe, parasitic infections after Tx are much less common than viral, bacterial and fungal ones. Read More

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May 2018
8 Reads

Impact of the health education and preventive equipment package (HEPEP) on prevention of Strongyloides stercoralis infection among rural communities in Northeast Thailand: a cluster randomized controlled trial.

BMC Public Health 2018 Oct 19;18(1):1184. Epub 2018 Oct 19.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Strongyloidiasis is prevalent in northeast Thailand. This study aimed to evaluate the impact of the Health Education and Preventive Equipment Package (HEPEP), a package we developed to improve awareness and aid in the prevention of Strongyloides stercoralis infection among rural communities in northeast Thailand.

Methods: This was an intervention trial conducted in 12 villages (six interventions and six controls) in rural areas of northeast Thailand from March 2016 to September 2017. Read More

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October 2018
2 Reads

Case Report: Subcutaneous Ivermectin Pharmacokinetics in Disseminated Infection: Plasma and Postmortem Analysis.

Am J Trop Med Hyg 2018 Sep 17. Epub 2018 Sep 17.

Pathology Queensland, Brisbane, Australia.

Parenteral ivermectin treatment of disseminated strongyloidiasis and hyperinfection is increasing, although not licensed in humans and with limited pharmacokinetic data available. Plasma and postmortem tissue analysis in an HIV/hepatitis C virus-positive man with disseminated strongyloidiasis suggests loading subcutaneous ivermectin doses are required, from which the central nervous system is protected. Read More

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September 2018
1 Read

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.

Wien Klin Wochenschr 2018 Oct 15;130(19-20):581-588. Epub 2018 Oct 15.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.

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October 2018
2 Reads

Donor-derived strongyloidiasis after organ transplantation in Norway.

Transpl Infect Dis 2018 Oct 8:e13008. Epub 2018 Oct 8.

Regional Advisory Unit for Imported and Tropical Diseases, Department of Infectious Diseases, Oslo University Hospital - Ullevål, Oslo, Norway.

Strongyloides stercoralis is an intestinal helminth which in humans can cause asymptomatic chronic infection maintained for decades through its auto-infective cycle. During solid organ transplantation, recipients may unintentionally receive an organ infected with strongyloides. This is a very rare complication but may have deadly outcome if not detected. Read More

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October 2018
1 Read

Case Report: Hyperinfection in a Patient with HTLV-1: A Case Report of an Infection with Filariform and Rhabditiform Larvae, Eggs, and Free-Living Adult Females.

Am J Trop Med Hyg 2018 Oct 1. Epub 2018 Oct 1.

Faculdade de Farmácia, Universidade Federal da Bahia (UFBA), Salvador, Brazil.

is the main etiological agent of human strongyloidiasis. Severe strongyloidiasis is commonly associated to alcoholism, corticostereoid use, and human T cell lymphotropic virus type 1 (HTLV-1) coinfection. Herein, we report a case of a 13-year-old boy coinfected with and HTLV-1, excreting several parasitic forms in the stool. Read More

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October 2018
7 Reads

Paediatric Strongyloidiasis in Central Australia.

Trop Med Infect Dis 2018 Jun 13;3(2). Epub 2018 Jun 13.

FRACP, Head of Department, Department of Paediatrics, Alice Springs Hospital, P.O. Box 2234, Alice Springs NT 0871, Australia.

Few published studies are available describing the prevalence of paediatric strongyloidiasis in endemic areas within Australia. This literature review and exploratory clinical audit presents the first seroprevalence data for paediatric patients in Central Australia. A total of 16. Read More

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June 2018
5 Reads

Argument for Inclusion of Strongyloidiasis in the Australian National Notifiable Disease List.

Trop Med Infect Dis 2018 Jun 5;3(2). Epub 2018 Jun 5.

College of Science and Engineering, Flinders University, Bedford Park, SA 5042, Australia.

Strongyloidiasis is an infection caused by the helminth, . Up to 370 million people are infected with the parasite globally, and it has remained endemic in the Indigenous Australian population for many decades. Strongyloidiasis has been also reported in other Australian populations. Read More

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June 2018
2 Reads

The Unique Life Cycle of Strongyloides stercoralis and Implications for Public Health Action.

Trop Med Infect Dis 2018 May 25;3(2). Epub 2018 May 25.

School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, QLD 4700, Australia.

has one of the most complex life cycles of the human-infecting nematodes. A common misconception in medical and public health professions is that in its biology is akin to other intestinal nematodes, such as the hookworms. Despite original evidence provided by medical and veterinary research about this unique helminth, many assumptions have entered the scientific literature. Read More

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May 2018
3 Reads

The Health Effects of Strongyloidiasis on Pregnant Women and Children: A Systematic Literature Review.

Trop Med Infect Dis 2018 May 18;3(2). Epub 2018 May 18.

College of Medicine and Dentistry, James Cook University, Smithfield QLD 4878, Australia.

Strongyloidiasis is a helminth infection that remains under-researched despite its ability to cause significant illness. Women and children may be at particular risk of health consequences from this parasite. This systematic literature review aims to examine research on the long-term health effects that strongyloidiasis has in pregnant women and children. Read More

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May 2018
6 Reads

A Community-Directed Integrated Control Program in Queensland, Australia.

Trop Med Infect Dis 2018 May 4;3(2). Epub 2018 May 4.

College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.

This paper describes two phases of a community-directed intervention to address strongyloidiasis in the remote Aboriginal community of Woorabinda in central Queensland, Australia. The first phase provides the narrative of a community-driven 'treat-and-test' mass drug administration (MDA) intervention that was co-designed by the Community Health Service and the community. The second phase is a description of the re-engagement of the community in order to disseminate the key factors for success in the previous MDA for , as this information was not shared or captured in the first phase. Read More

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May 2018
1 Read

Cross-Cultural, Aboriginal Language, Discovery Education for Health Literacy and Informed Consent in a Remote Aboriginal Community in the Northern Territory, Australia.

Trop Med Infect Dis 2018 Jan 29;3(1). Epub 2018 Jan 29.

School of Health, Medical and Applied Sciences, Central Queensland University, Bundaberg, QLD 4670, Australia.

Background: Education for health literacy of Australian Aboriginal people living remotely is challenging as their languages and worldviews are quite different from English language and Western worldviews. Becoming health literate depends on receiving comprehensible information in a culturally acceptable manner.

Methods: The study objective was to facilitate oral health literacy through community education about scabies and strongyloidiasis, including their transmission and control, preceding an ivermectin mass drug administration (MDA) for these diseases. Read More

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January 2018
3 Reads

Application of PCR-Based Tools to Explore Strongyloides Infection in People in Parts of Northern Australia.

Trop Med Infect Dis 2017 Dec 8;2(4). Epub 2017 Dec 8.

School of Health, Medical and Applied Sciences, Central Queensland University, North Rockhampton, QLD 4700, Australia.

Strongyloidiasis, which is caused by infection with the nematode , is endemic to areas of northern Australia. Diagnosis in this region remains difficult due to the distances between endemic communities and diagnostic laboratories, leading to lengthy delays in stool processing for microscopy and culture. PCR represents a viable solution to this difficulty, having potential for high sensitivity detection of , even in older, unpreserved faecal samples. Read More

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December 2017
3 Reads

Soil-Transmitted Helminths in Children in a Remote Aboriginal Community in the Northern Territory: Hookworm is Rare but Strongyloides stercoralis and Trichuris trichiura Persist.

Trop Med Infect Dis 2017 Oct 4;2(4). Epub 2017 Oct 4.

Menzies School of Health Research, Charles Darwin University, Darwin NT 0811, Australia.

(1) Background: soil-transmitted helminths are a problem worldwide, largely affecting disadvantaged populations. The little data available indicates high rates of infection in some remote Aboriginal communities in Australia. Studies of helminths were carried out in the same remote community in the Northern Territory in 1994⁻1996 and 2010⁻2011; (2) Methods: fecal samples were collected from children aged <10 years and examined for helminths by direct smear microscopy. Read More

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October 2017
1 Read

A case of chronic strongyloidiasis diagnosed by histopathological study.

Int J Infect Dis 2018 Dec 24;77:1-2. Epub 2018 Sep 24.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024 Negrar, Italy. Electronic address:

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December 2018
9 Reads

Pulmonary strongyloidiasis presenting micronodules on chest computed tomography.

J Thorac Dis 2018 Aug;10(8):E612-E615

Department of Parasitology and Tropical Medicine, and Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.

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August 2018
1 Read

Case Report: Ivermectin and Albendazole Plasma Concentrations in a Patient with Disseminated Strongyloidiasis on Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy.

Am J Trop Med Hyg 2018 Nov;99(5):1194-1197

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

Disseminated strongyloidiasis is often fatal, despite treatment with oral albendazole and parenteral ivermectin (IVM). Here, we report elevated plasma IVM and albendazole sulfoxide concentrations in the context of extracorporeal membrane oxygenation and continuous renal replacement therapy in a patient with disseminated strongyloidiasis treated with subcutaneous IVM and nasogastric albenzadole. Despite elevated drug plasma concentrations, live filariform larvae were detected in endotracheal aspirates after 2 weeks of treatment. Read More

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November 2018
17 Reads

Disseminated Strongyloidiasis in Association with Nephrotic Syndrome.

Case Rep Nephrol Dial 2018 May-Aug;8(2):155-160. Epub 2018 Aug 10.

Internal Medicine Residency, Guthrie Robert Packer Hospital, Sayre, Pennsylvania, USA.

Strongyloidiasis is a well-known parasitic infection endemic in tropical and subtropical areas of the world. While most infected individuals are asymptomatic, strongyloidiasis-related glomerulopathy has not been well documented. We present a case of disseminated strongyloidiasis in a patient with minimal change nephrotic syndrome treated with high-dose corticosteroids. Read More

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August 2018
11 Reads

Enterobius vermicularis infection mimicking strongyloidiasis: A case report.

J Microbiol Immunol Infect 2018 Dec 25;51(6):858-859. Epub 2018 Aug 25.

Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan; Department of Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan; China Medical University, Taichung, Taiwan.

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December 2018
5 Reads

Parasitic infections in the intensive care unit.

Anaesth Intensive Care 2018 Sep;46(5):546-548

Saarland University Medical Center.

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September 2018
1 Read

Strongyloidiasis Presenting as Yellowish Nodules in Colonoscopy of an Immunocompetent Patient.

Clin Endosc 2018 Aug 30. Epub 2018 Aug 30.

Department of Internal Medicine, Gachon University of Medical and Science, Incheon, Korea.

Strongyloides stercoralis is endemic to tropical and subtropical regions, and infections are usually asymptomatic. However, immunocompromised patients, such as those receiving immunosuppressive therapy, high-dose steroids, or chemotherapy, can develop fatal hyperinfections. An 84-year-old man without any symptoms was diagnosed with strongyloidiasis during a regular screening colonoscopy. Read More

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August 2018
6 Reads

Strongyloidiasis in humans: diagnostic efficacy of four conventional methods and real-time polymerase chain reaction.

Rev Soc Bras Med Trop 2018 Jul-Aug;51(4):493-502

Grupo Biología de Sistemas, Escuela de Ciencias de la Salud, Facultad de Medicina, Universidad Pontificia Bolivariana, Medellín ,Colombia.

Introduction: Strongyloides stercoralis is an intestinal parasitic nematode that causes hyperinfection and/or a dissemination syndrome in hosts, which is often difficult to diagnose. This study aims to compare the diagnostic efficacy of four conventional methods used to diagnose strongyloidiasis with real-time polymerase chain reaction (qPCR) to detect S. stercoralis in fecal samples. Read More

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September 2018
3 Reads

[A disseminated strongyloidiasis in a non immunocompromised patient].

Rev Med Liege 2018 Jul;73(7-8):383-386

Service d'Infectiologie, Centre Hospitalier du Luxembourg, Luxembourg.

Strongyloidiasis is a parasitosis mainly located in tropical and subtropical regions. Its European incidence is increasing due to population migration. The symptomatology is variable, largely depending on the host immune status. Read More

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July 2018
2 Reads

Late post-kidney transplant Strongyloides hyperinfection syndrome.

Transpl Infect Dis 2018 Aug 14:e12975. Epub 2018 Aug 14.

Division of Infectious Diseases & International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.

Disseminated strongyloidiasis is a potentially life-threatening infection in organ transplant recipients that typically occurs within the first 6 months of transplantation. We discuss a patient from the Appalachia region of Virginia who appeared to acquire Strongyloides stercoralis domestically years after kidney transplantation and then develop disseminated strongyloidiasis. Read More

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August 2018
17 Reads

Chronic intestinal pseudo-obstruction due to .

IDCases 2018 9;13:e00425. Epub 2018 Jul 9.

Western Michigan University Homer Stryker M.D. School of Medicine, 1000 Oakland Drive, Kalamazoo Michigan 49008, United States.

We report a case of chronic intestinal pseudo-obstruction due to a generalized visceral autonomic neuropathy in an immune-competent patient infected with . The patient had immigrated to the United States from Sierra Leone in childhood but had not returned for decades. His symptoms resolved with ivermectin treatment. Read More

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July 2018
2 Reads

Global output of research on epidermal parasitic skin diseases from 1967 to 2017.

Authors:
Waleed M Sweileh

Infect Dis Poverty 2018 Aug 6;7(1):74. Epub 2018 Aug 6.

Department of Physiology, Pharmacology/Toxicology, Division of Biomedical Sciences, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

Background: Epidermal parasitic skin diseases (EPSD) occur in most countries and cause a considerable health and economic burden, particularly in the tropics and subtropics. The aim of this study was to assess and analyse peer-reviewed literature on EPSD in humans. The results of this study serve as an indicator of the extent the scientific community, health authorities, and international health agencies interact with EPSD as a health problem that is commonly associated with poverty and poor hygiene. Read More

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August 2018
5 Reads
2 PubMed Central Citations(source)

Diagnostic comparison of Baermann funnel, Koga agar plate culture and polymerase chain reaction for detection of human Strongyloides stercoralis infection in Maluku, Indonesia.

Parasitol Res 2018 Oct 3;117(10):3229-3235. Epub 2018 Aug 3.

Postgraduate Programme of Tropical Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Human infection with the nematode Strongyloides stercoralis, which may have a life-threatening course, primarily occurs in tropical settings. Epidemiological data on the occurrence of strongyloidiasis are scarce, and microscopic stool-based detection methods are insensitive. Polymerase chain reaction (PCR) assays have been developed, yet conflicting results have been reported. Read More

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October 2018

Investigations for the Possible Use of a Monoclonal Antibody Produced against Antigen as an Immunodiagnostic Reagent for Active Strongyloidiasis.

Iran J Parasitol 2018 Apr-Jun;13(2):204-214

Dept. of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia.

Background: Currently, most of the available serological diagnostic kits for strongyloidiasis are based on the use of the crude antigens of , which are good, but with less sensitivity towards the infection. Hence, this study aimed to produce and evaluate monoclonal antibody for detecting soluble parasite antigen in animal sera.

Methods: The study was conducted in the Department of Medical Microbiology and Parasitology, University Putra Malaysia in 2014-2017. Read More

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August 2018
6 Reads
0.870 Impact Factor

OCCASIONAL DIGESTIVE HEMORRHAGE IN CHILDREN DUE TO STRONGYLOIDIASIS: IMPORTANCE OF PARASITOLOGIC TESTING.

Rev Paul Pediatr 2018 Jul 26. Epub 2018 Jul 26.

Laboratório de Análises Clínicas Vida EireliEpp, Videira, SC, Brasil.

Objective: To describe an uncommon case of infection by Strongyloides stercoralis (S. stercoralis) in a 4-month-old child and to highlight the importance of early diagnosis.

Case Description: The patient was a male child from the city of Videira, State of Santa Catarina, Southern Brazil, who was born preterm by Cesarean-section, weighing 1,655 g, and stayed in the neonatal intensive care unit for 20 days. Read More

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July 2018
2 Reads

Current high prevalences of Strongyloides stercoralis and Opisthorchis viverrini infections in rural communities in northeast Thailand and associated risk factors.

BMC Public Health 2018 Jul 31;18(1):940. Epub 2018 Jul 31.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Two important helminths, Strongyloides stercoralis (an intestinal roundworm) and Opisthorchis viverrini (a liver fluke), are endemic in northeast Thailand. There have been national campaigns in place aimed at the control and eradication of soil-transmitted helminthiasis and opisthorchiasis in Thailand for several decades. However, these helminths still exist and raise concerns regarding public health. Read More

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July 2018
2 Reads

Inducible nitric oxide synthase controls experimental Strongyloides infection.

Parasite Immunol 2018 Oct 23;40(10):e12576. Epub 2018 Aug 23.

Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.

Infection with Strongyloides sp. induces a host immune response, predominantly the Th2 type, that is able to eliminate the parasite. However, little is known about the role of the nitric oxide (NO) mediator, induced by the enzyme nitric oxide synthase (NOS), in strongyloidiasis. Read More

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October 2018
1 Read

First molecular identification of Strongyloides fuelleborni in long-tailed macaques in Thailand and Lao People's Democratic Republic reveals considerable genetic diversity.

J Helminthol 2018 Jul 20:1-8. Epub 2018 Jul 20.

Department of Parasitology,Faculty of Medicine, and Research and Diagnostic Center for Infectious Diseases,Khon Kaen University,40002,Thailand.

Strongyloides fuelleborni is a soil-transmitted nematode parasite of non-human primates. The worm is prevalent also in human populations in Africa and South-East Asia. In this study, we amplified and sequenced a portion of the 18S ribosomal RNA gene (rRNA) and of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene of Strongyloides adult males recovered from faecal samples from long-tailed macaques (Macaca fascicularis) in Thailand and Lao PDR. Read More

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July 2018
8 Reads

Screening for infectious diseases in newly arrived migrants in Europe: the context matters.

Euro Surveill 2018 Jul;23(28)

European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

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July 2018
1 Read

Diagnostic performance of urinary IgG antibody detection: A novel approach for population screening of strongyloidiasis.

PLoS One 2018 9;13(7):e0192598. Epub 2018 Jul 9.

Department of Microbiology, Immunology & Tropical Medicine, George Washington University, Washington, D.C., United States of America.

The diagnosis of strongyloidiasis by coprological methods has a low sensitivity, underestimating the prevalence of Strongyloides stercoralis in endemic areas. Serodiagnostic tests for strongyloidiasis have shown robust diagnostic properties. However, these methods require a blood draw, an invasive and labor-intensive sample collection method, especially in the resource-limited settings where S. Read More

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July 2018
6 Reads

Fatal Strongyloides hyperinfection syndrome in an immunocompetent adult with review of the literature.

Intern Med J 2018 07;48(7):872-875

Department of Infectious Diseases, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Strongyloides hyperinfection syndrome is rarely described in immunocompetent individuals. We present a case of fatal Strongyloides hyperinfection syndrome, and a literature review identifying nine other cases occurring in immunocompetent individuals, highlighting the challenges of diagnosis and treatment in this setting. While overall mortality is lower compared to immunocompromised patients, fatal outcomes still occur. Read More

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July 2018
1 Read

Strongyloides stercoralis: detection of parasite-derived DNA in serum samples obtained from immunosuppressed patients.

Parasitol Res 2018 Sep 5;117(9):2927-2932. Epub 2018 Jul 5.

Department of Mycology and Parasitology, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

Strongyloidiasis is an important neglected disease, which is life threatening in immunocompromised patients. This study aimed to evaluate the frequency of Strongyloides stercoralis infection among immunosuppressed subjects living in endemic communities by conventional PCR of the 18S rRNA and Cox1 genes to detect cell-free DNA in the patients' serum samples. Fresh stool and serum samples were obtained from participants. Read More

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September 2018
15 Reads

Pulmonary strongyloidiasis causing septic shock in a patient with Crohn's disease.

Respir Med Case Rep 2018 6;24:52-54. Epub 2018 Apr 6.

Presence St Francis Hospital, Evanston, IL, USA.

A 58 years old male who was admitted to the intensive care unit for septic shock secondary to pneumonia, he has Crohn's disease currently treated with Vedolizumab and previously with infliximab. He was started on broad spectrum antibiotics and vasopressors for treatment of septic shock without improvement in the following days, sputum & blood cultures were negative. Bronchoscopy was done for non-resolving pneumonia work up, broncheoalveolar lavage smears and cultures were negative for bacteria, tuberculosis and Fungi. Read More

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April 2018
4 Reads