4,001 results match your criteria Strongyloidiasis


2018 in review: five hot topics in tropical medicine.

Trop Dis Travel Med Vaccines 2019 15;5. Epub 2019 Apr 15.

2Tropical Disease Unit, Toronto General Hospital, 200 Elizabeth Street, 13EN-218, Toronto, ON M5G 2C4 Canada.

The year 2018 heralded many new developments in the field of tropical medicine, including licensure of novel drugs for novel indications, licensure of existing drugs for existing indications but in novel settings, and globalized outbreaks of both vector-borne and zoonotic diseases. We herein describe five top stories in tropical medicine that occurred during 2018, and illuminate the practice-changing development within each story. Read More

View Article

Download full-text PDF

Source
https://tdtmvjournal.biomedcentral.com/articles/10.1186/s407
Publisher Site
http://dx.doi.org/10.1186/s40794-019-0082-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466725PMC
April 2019
1 Read

Disseminated Strongyloidiasis: Breaking Brain Barriers.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):234-237

Department of Infectious Diseases, Wayne State School of Medicine, Detroit, Michigan, USA.

(SS) is one of the most overlooked helminthic infections despite being highly endemic in tropical and subtropical areas. In immunocompromised patients, especially those on long-term steroids, infection can often escalate to fatal dissemination into major organs. We present a compendium of two immunocompromised patients, who were on high-dose steroids and presented with worsening neurological status. Read More

View Article

Download full-text PDF

Source
http://www.annalsofian.org/preprintarticle.asp?id=249718
Publisher Site
http://dx.doi.org/10.4103/aian.AIAN_321_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472231PMC
April 2019
4 Reads

Parasitic Infections of the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient, Including Toxoplasmosis and Strongyloidiasis.

Infect Dis Clin North Am 2019 Jun;33(2):567-591

A. C. Camargo Cancer Center, Rua Professor Antonio Prudente, 211, Sao Paulo CEP: 01509-010, Brazil; Emilio Ribas Infectious Diseases Institute, Av. Doutor Arnaldo, 165, Sao Paulo CEP: 01246-900, Brazil.

Hematopoietic stem cell transplantation (HSCT) recipients may infrequently develop parasitic infections at the time of the procedure via contamination from allograft tissue or blood products, and in the post-transplantation period through the traditional route of infection or as a reactivation caused by immunosuppression related to the transplant. To reduce risk, efforts should be directed at performing a comprehensive history, maintaining a high index of suspicion, and adhering to preventive measures. Additional strategies for the prevention, screening and careful follow-up, identification, and pre-emptive treatment of parasitic infections are required to reduce morbidity and mortality in HSCT patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.idc.2019.02.009DOI Listing

Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome.

Trop Dis Travel Med Vaccines 2019 3;5. Epub 2019 Apr 3.

1University of Toronto, 27 King's College Circle, Toronto, Ontario M5S1A1 Canada.

Background: Strongyloidiasis is a common infection in Canadian migrants that can cause life-threatening hyperinfection in immunosuppressed hosts. We designed and implemented a safety tool to guide management of patients with in order to prevent adverse outcomes. Methods: Patients treated at our centre for strongyloidiasis from January 1, 2013 to December 31, 2015 were identified through our ivermectin access log. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40794-019-0080-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448213PMC
April 2019
1 Read

In vitro anthelmintic activity of Siparuna guianensis extract and essential oil against Strongyloides venezuelensis.

J Helminthol 2019 Apr 11:1-5. Epub 2019 Apr 11.

Laboratório de Parasitologia,Universidade Federal de Jataí,Jataí,GO, 75.801-615,Brazil.

New therapeutic approaches are necessary to control strongyloidiasis due to the side effects of, and resistance to, currently available drugs thiabendazole, albendazole, and ivermectin. This study examined the anthelmintic properties of extracts and isolated compounds from Siparuna guianensis against Strongyloides venezuelensis eggs and larvae, using the egg hatching test (EHT) and larval motility test (LMT). Albendazole (0. Read More

View Article

Download full-text PDF

Source
https://www.cambridge.org/core/product/identifier/S0022149X1
Publisher Site
http://dx.doi.org/10.1017/S0022149X19000282DOI Listing
April 2019
2 Reads

Corticosteroid-induced immunodeficiency in a patient with gliomatosis cerebri: Are corticosteroids indicated in all brain tumors?

Clin Neuropathol 2019 Apr 9. Epub 2019 Apr 9.

An elderly male was admitted to the Department of Neurology for slowly progressive dysarthria and right-sided atactic hemiparesis. Magnetic resonance imaging (MRI) revealed a small contrast-enhanced focus of malignant glioma in the left parietal lobe - with the growth pattern of cerebral gliomatosis - involving the whole left cerebral hemisphere, the corpus callosum, and spreading into the right frontal hemisphere. Diagnostic biopsy was deferred until the exclusion of other possible causes of the brain lesion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5414/NP301167DOI Listing
April 2019
1 Read

Morbidity Associated with Chronic Infection: A Systematic Review and Meta-Analysis.

Am J Trop Med Hyg 2019 Apr 8. Epub 2019 Apr 8.

IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.

, a worldwide-distributed soil-transmitted helminth, causes chronic infection which may be life threatening. Limitations of diagnostic tests and nonspecificity of symptoms have hampered the estimation of the global morbidity due to strongyloidiasis. This work aimed at assessing -associated morbidity through a systematic review and meta-analysis of the available literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4269/ajtmh.18-0895DOI Listing
April 2019
2 Reads

Gastrointestinal effects of ivermectin treatment in rats infected with Strongyloides venezuelensis.

Acta Trop 2019 Mar 23;194:69-77. Epub 2019 Mar 23.

Federal University of Mato Grosso - UFMT, Barra do Garças, MT, Brazil. Electronic address:

We aimed to evaluate the effects of ivermectin treatment on gastrointestinal morphology and function after Strongyloides venezuelensis infection. Male rats composed Control (C), Parasitized (Sv), Ivermectin (IVM) and Parasitized and treated with Ivermectin (Sv/IVM) groups. IVM and Sv/IVM groups were subdivided according to IVM: single dose of 200 μg/kg (IVM1 and Sv/IVM1) or three repeated doses of 200 μg/kg at 24 h intervals (IVM3 and Sv/IVM3). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.actatropica.2019.03.024DOI Listing
March 2019
1 Read

infection as a reversible cause of chronic urticaria.

J Asthma Allergy 2019 26;12:67-69. Epub 2019 Feb 26.

Department of Allergy, Immunology and Respiratory Medicine, Alfred Health, Melbourne, VIC, Australia,

Recurrent urticaria is a frequent presenting complaint in the Allergy Clinic, despite the fact that chronic urticaria is not an IgE-mediated (atopic) condition in most cases. We present four cases assessed over 5 years in our allergy service who were found to have evidence of strongyloidiasis and whose clinical features resolved with standard anti-helminth treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/JAA.S167292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396652PMC
February 2019
1 Read

Strongyloides stercoralis infection: A systematic review of endemic cases in Spain.

PLoS Negl Trop Dis 2019 03 12;13(3):e0007230. Epub 2019 Mar 12.

Department of Infectious Diseases, Vall d'Hebron University Hospital, PROSICS Barcelona, Spain.

Background: Strongyloides stercoralis infection, a neglected tropical disease, is widely distributed. Autochthonous cases have been described in Spain, probably infected long time ago. In recent years the number of diagnosed cases has increased due to the growing number of immigrants, travelers and refugees, but endemically acquired cases in Spain remains undetermined. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0007230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413904PMC
March 2019
1 Read

[Severe infection by Strongyloides stercoralis in ascitic liquid].

Rev Gastroenterol Peru 2018 Oct-Dec;38(4):377-380

Municipalidad de San Isidro. Lima, Perú.

The strongyloidiasis is an infection whose responsible agents are Strongyloides stercoralis and S. fuelleborni. These nematodes have an intestinal location; the main risk factor is to be barefoot in places contaminated with filariform larvae. Read More

View Article

Download full-text PDF

Source
March 2019
7 Reads

Production of recombinant 14-3-3 protein and determination of its immunogenicity for application in serodiagnosis of strongyloidiasis.

Trans R Soc Trop Med Hyg 2019 Mar 11. Epub 2019 Mar 11.

Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Background: Strongyloides stercoralis is the fourth most important intestinal nematode worldwide. The parasite load and larvae count are often low, thus conventional methods are not sufficiently sensitive to detect the infection. In this study we developed an immunoglobulin G-based enzyme-linked immunosorbent assay (ELISA) method to detect antibodies against S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/trstmh/trz006DOI Listing
March 2019
4 Reads

[Strongyloidiasis, a sexually transmitted disease].

Presse Med 2019 Mar 8;48(3 Pt 1):322-324. Epub 2019 Mar 8.

Service des maladies infectieuses, Hôtel-Dieu, place du Parvis de Notre-Dame, 75004 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lpm.2019.02.028DOI Listing

Implementation of a Strongyloides screening strategy in solid organ transplant donors and recipients.

Clin Transplant 2019 Apr 12;33(4):e13497. Epub 2019 Mar 12.

Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida.

Background: Strongyloides stercoralis infects 100 million people worldwide. Mortality rates in hyperinfection syndrome exceed 50%. Donor-derived Strongyloides infection has occurred after heart, kidney, kidney-pancreas and liver transplantation; yet, only 10% of the US organ procurement organizations currently screen donors for strongyloidiasis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ctr.13497DOI Listing
April 2019
3 Reads

Comparison of ELISA and PCR of the 18S rRNA gene for detection of human strongyloidiasis using serum sample.

Infect Dis (Lond) 2019 May 18;51(5):360-367. Epub 2019 Feb 18.

c Cellular and Molecular Biology Research Center, Health Research Institute , Babol University of Medical Sciences , Babol , Iran.

Background: Strongyloides stercoralis infection is a neglected tropical disease with global distribution which is fatal in immunosuppressed patients. This study aimed to determine the prevalence of strongyloidiasis in immunocompromised individuals and cases with infectious diseases, as well as comparing ELISA and conventional PCR with coprological examination, in the central parts of Mazandaran province, northern Iran.

Methods: A single serum and a fresh stool samples were obtained from 272 and 220 patients, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/23744235.2019.1575978DOI Listing
May 2019
1 Read

The Experimental Infections of the Human Isolate of Strongyloides Stercoralis in a Rodent Model (The Mongolian Gerbil, Meriones Unguiculatus).

Pathogens 2019 Feb 5;8(1). Epub 2019 Feb 5.

Lymphatic Filariasis and Tropical Medicine Research Unit, Chulalongkorn Medical Research Center, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Strongyloidiasis is life-threatening disease which is mainly caused by infection. Autoinfection of the parasite results in long-lasting infection and fatal conditions, hyperinfection and dissemination (primarily in immunosuppressed hosts). However, mechanisms of autoinfection and biology remain largely unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/pathogens8010021DOI Listing
February 2019
1 Read

The investigation of Strongyloides stercoralis seroprevalence in immunosupressed patients in Turkey

Turk J Med Sci 2019 Feb 11;49(1):16-19. Epub 2019 Feb 11.

Background/aim: In immunosuppressed patients, strongyloidiasis can be lifethreatening because of hyperinfection or dissemination. Therefore, diagnosis of S. stercoralis is important in immunosuppressed patients with chronic strongyloidiasis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3906/sag-1804-16DOI Listing
February 2019
1 Read

Hemoptysis in the Immunocompromised Patient: Do Not Forget Strongyloidiasis.

Trop Med Infect Dis 2019 Feb 12;4(1). Epub 2019 Feb 12.

Department of Medicine, Division of Infectious Diseases, University of Texas Health, San Antonio, TX 78229, USA.

Strongyloidiasis, due to infection with the nematode , affects millions of people in the tropics and subtropics. has a unique auto-infective lifecycle such that it can persist in the human host for decades. In immunosuppressed patients, especially those on corticosteroids, potentially fatal disseminated strongyloidiasis can occur, often with concurrent secondary infections. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/tropicalmed4010035DOI Listing
February 2019
1 Read

Lethal strongyloidiasis - Diagnostic and forensic issues.

Authors:
Roger W Byard

J Forensic Leg Med 2019 Feb 2;62:103-106. Epub 2019 Feb 2.

School of Medicine, Level 2 Medical School North Building, The University of Adelaide, Frome Road, Forensic Science South Australia (FSSA), Adelaide, 5005, SA, Australia. Electronic address:

Strongyloidiasis is an infectious disease affecting approximately 30-100 million people globally. The main human pathogen is Strongyloides stercoralis which may cause a brief period of acute symptoms and signs after the initial infection, and then lapse into a chronic asymptomatic carrier state for decades due to the nematode's unique ability to autoinfect hosts. Immunosuppression from steroid therapy, T-lymphocytic viral (HTLV-1) infections, or a variety of underlying medical conditions may then result in dissemination and the highly lethal and infectious hyperinfection syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jflm.2019.01.014DOI Listing
February 2019
3 Reads

Comparison of Loop-Mediated Isothermal Amplification and Real-Time PCR Assays for Detection of Strongyloides Larvae in Different Specimen Matrices.

J Clin Microbiol 2019 Apr 28;57(4). Epub 2019 Mar 28.

Parasitology Laboratory, Centre for Infectious Diseases and Microbiology, Institute for Clinical Pathology and Medical Research-New South Wales Health Pathology, Westmead Hospital, Westmead, New South Wales, Australia.

can cause disease that ranges from asymptomatic chronic infection to fatal hyperinfection. Diagnosis from stool can be challenging because the most sensitive conventional tests require live larvae to be effective and there can be low larval output in chronic infection. Nucleic acid amplification tests (NAAT) have been developed to complement existing diagnostic methods. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JCM.01173-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440779PMC
April 2019
3 Reads

Migration Medicine.

Infect Dis Clin North Am 2019 Mar;33(1):265-287

University Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili, Piazza del Mercato, 15, Lombardy, Brescia 25121, Italy; UNESCO Chair "Training and Empowering Human Resources for Health Development in Resource-Limited Countries", University of Brescia, Brescia, Italy.

Migration is increasing and practitioners need to be aware of the unique health needs of this population. The prevalence of infectious diseases among migrants varies and generally mirrors that of their countries of origin, but is modified by the circumstance of migration, the presence of pre-arrival screening programs and post arrival access to health care. To optimize the health of migrants practitioners; (1) should take all opportunities to screen migrants at risk for latent infections such as tuberculosis, chronic hepatitis B and C, HIV, strongyloidiasis, schistosomiasis and Chagas disease, (2) update routine vaccines in all age groups and, (3) be aware of "rare and tropical infections" related to migration and return travel. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.idc.2018.10.014DOI Listing
March 2019
10 Reads

Strongyloidiasis: A Neglected Tropical Disease.

Infect Dis Clin North Am 2019 Mar;33(1):135-151

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 - Room B1-03, 4 Center Drive, Bethesda, MD 20892-0425, USA. Electronic address:

Most of the 30 to 100 million people infected with Strongyloides stercoralis have subclinical (or asymptomatic) infections. These infections are commonly chronic and longstanding. A change in immune status can increase parasite numbers, leading to hyperinfection syndrome, dissemination, and death if unrecognized. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08915520183009
Publisher Site
http://dx.doi.org/10.1016/j.idc.2018.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367705PMC
March 2019
5 Reads

Prevalence of strongyloidiasis and schistosomiasis among migrants: a systematic review and meta-analysis.

Lancet Glob Health 2019 Feb;7(2):e236-e248

Centre for Clinical Epidemiology of the Lady Davis Institute for Medical Research, McGill University, Montreal, QC, Canada; Division of Infectious Diseases and Clinical Epidemiology, SMBD Jewish General Hospital, McGill University, Montreal, QC, Canada. Electronic address:

Background: Global migration from regions where strongyloidiasis and schistosomiasis are endemic to non-endemic countries has increased the potential individual and public health effect of these parasitic diseases. We aimed to estimate the prevalence of these infections among migrants to establish which groups are at highest risk and who could benefit from screening.

Methods: We did a systematic review and meta-analysis of strongyloidiasis and schistosomiasis prevalence among migrants born in endemic countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2214-109X(18)30490-XDOI Listing
February 2019
4 Reads

Strongyloidiasis and schistosomiasis: lessons from migrants' data.

Lancet Glob Health 2019 Feb;7(2):e171-e172

Department of Medical Parasitology, School of Medicine, Catholic University of Health and Allied Sciences, PO Box 1464, Mwanza, Tanzania. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2214-109X(18)30522-9DOI Listing
February 2019
2 Reads

Disseminated Strongyloidiasis.

Acta Dermatovenerol Croat 2018 Dec;26(4):333-336

Professor Marcia Ramos-e-Silva, MD, PhD, Rua Dona Mariana 143 / C-32, Rio de Janeiro 22280-020, Brazil;

Strongyloidiasis is a parasitic infestation caused by the helminth Strongyloides stercoralis. It is essentially gastrointestinal and in general asymptomatic but can sometimes present with skin signs. Immunocompromised patients can develop the disseminated form of the disease due to the parasite's opportunistic behavior, as in cases of coinfection by the human T-lymphotropic type 1 virus (HTLV-1). Read More

View Article

Download full-text PDF

Source
December 2018
10 Reads

Epidemiology of Strongyloides stercoralis infection in Bolivian patients at high risk of complications.

PLoS Negl Trop Dis 2019 01 17;13(1):e0007028. Epub 2019 Jan 17.

Division of Tropical and Humanitarian Medicine, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

Background: Strongyloidiasis can be fatal in immunocompromised patients, but few epidemiological studies investigated the burden of this neglected tropical disease among these populations, particularly in low- and middle-income countries such as Bolivia. This study aimed to fill in this gap by estimating prevalence rate and risk factors associated with strongyloidiasis among patients at high risk of complications.

Methods: A cross-sectional study was carried out in Santa Cruz (elevation 400 meters, tropical climate) and Cochabamba (elevation 2,500 meters, temperate climate), among patients with cancer, HIV infection and rheumatic or hematologic disease, using four coproparasitological techniques and one serological (ELISA) test. Read More

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pntd.0007028
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0007028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353209PMC
January 2019
12 Reads

Central nervous system Strongyloides stercoralis. A case report.

Turk Neurosurg 2018 Sep 28. Epub 2018 Sep 28.

Medifema Hospital.

Strongyloidiasis is an infestation caused by the intestinal nematode Strongyloides stercoralis. It is potentially fatal in immuno-compromised hosts due to its capacity to cause an overwhelming hyperinfestation however infested healthy individuals are usually asymptomatic. Hyperinfestation is extremely rare in the Central Nervous System (CNS) and usually limited to the gastrointestinal tract or lungs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5137/1019-5149.JTN.22886-18.2DOI Listing
September 2018
4 Reads

Diagnostic update for an unusual case: recurrent strongyloidiasis.

J R Army Med Corps 2019 Jan 13. Epub 2019 Jan 13.

Army Medical Services Support Unit, Camberley, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jramc-2018-001143DOI Listing
January 2019
1 Read

Secretome analysis of Strongyloides venezuelensis parasitic stages reveals that soluble and insoluble proteins are involved in its parasitism.

Parasit Vectors 2019 Jan 9;12(1):21. Epub 2019 Jan 9.

Division of Parasitology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.

Background: Parasites excrete and secrete a wide range of molecules that act as the primary interface with their hosts and play critical roles in establishing parasitism during different stages of infection. Strongyloides venezuelensis is a gastrointestinal parasite of rats that is widely used as a laboratory model and is known to produce both soluble and insoluble (adhesive) secretions during its parasitic stages. However, little is known about the constituents of these secretions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13071-018-3266-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327390PMC
January 2019
4 Reads

In-vitro Anthelmintic Effects of Aqueous and Ethanolic Extracts of Marrubium vulgare Leaves Against Bovine Digestive Strongyles.

Turkiye Parazitol Derg 2018 Dec;42(4):262-267

Department of Biological Sciences of Environment, University A. Mira, School of Life and Nature Sciences, Bejaia, Algeria.

Objective: The aim of the present study was to evaluate in vitro the anthelmintic activity of Marrubium vulgare L. growing in Algeria against digestive strongyles in naturally infected bovine.

Methods: The anthelmintic activities of the extracts were evaluated using the egg hatch assay and larval mortality assay. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/tpd.2018.5972DOI Listing
December 2018
1 Read

Prevalence and associated risk factors of infection in Lower Myanmar.

Trop Med Health 2018 18;46:43. Epub 2018 Dec 18.

2Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692 Japan.

Background: Strongyloidiasis is prevalent in Southeast Asian regions along with other soil-transmitted helminthiases, but only limited present-day data was available for Myanmar.

Methods: A prevalence survey for infection was conducted among villagers in rural areas of three townships located in the Lower Myanmar during 2014-2016 by agar plate culture method in combination with specific identification by molecular assays. Risk factors associated with infection were assessed by analyzing questionnaires obtained from study participants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s41182-018-0126-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299610PMC
December 2018
3 Reads

Is Strongyloides seropositivity associated with diabetes mellitus? A retrospective case-control study in an East London NHS Trust.

Trans R Soc Trop Med Hyg 2019 Apr;113(4):189-194

Division of Infection, Barts Health NHS Trust, London, United Kingdom.

Background: The association between diabetes and Strongyloides stercoralis remains controversial. We conducted a case-control study examining the association between diabetes and Strongyloides seropositivity in a large UK centre.

Methods: Between January 2013 and October 2016, cases and controls were identified by positive and negative Strongyloides serology, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/trstmh/try132DOI Listing
April 2019
2 Reads

Donor-derived strongyloidiasis in a Saudi pediatric kidney transplant recipient: A case report and mini-review.

Pediatr Transplant 2019 03 21;23(2):e13315. Epub 2018 Dec 21.

Division of Pediatric Infectious Diseases, King Abdullah Specialized Children's Hospital (KASCH), National Guard Health Affairs, Riyadh, Saudi Arabia.

S. stercoralis infection has been identified as a donor-derived infection in cases of solid organ transplant among recipients with no prior risk factor for parasitic exposure. Worldwide and regional reports from the adult kidney transplant population highlight this indirect method of infection and caution about delayed diagnosis, severe complications, and death related to donor-derived S. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/petr.13315
Publisher Site
http://dx.doi.org/10.1111/petr.13315DOI Listing
March 2019
17 Reads

Effectiveness of Screening and Treatment Approaches for Schistosomiasis and Strongyloidiasis in Newly-Arrived Migrants from Endemic Countries in the EU/EEA: A Systematic Review.

Int J Environ Res Public Health 2018 12 20;16(1). Epub 2018 Dec 20.

ISGlobal, Barcelona Institute for Global Health (ISGlobal-CRESIB, Hospital Clínic-University of Barcelona), E-08036 Barcelona, Spain.

We aimed to evaluate the evidence on screening and treatment for two parasitic infections-schistosomiasis and strongyloidiasis-among migrants from endemic countries arriving in the European Union and European Economic Area (EU/EEA). We conducted a systematic search of multiple databases to identify systematic reviews and meta-analyses published between 1 January 1993 and 30 May 2016 presenting evidence on diagnostic and treatment efficacy and cost-effectiveness. We conducted additional systematic search for individual studies published between 2010 and 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph16010011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339107PMC
December 2018
3 Reads

IgG reactivity with 40-35 kDa soluble and membrane antigen of Strongyloides venezuelensis in immunocompromised patients.

Acta Trop 2019 Feb 12;190:357-360. Epub 2018 Dec 12.

Laboratório de Investigação Médica (LIM/06 - Laboratório de Imunopatologia da Esquistossomose), Hospital das Clínicas da Faculdade de Medicina, USP, São Paulo, Brazil; Instituto de Medicina Tropical de São Paulo, USP, São Paulo, Brazil.

Immunocompromised patients constitute a risk group for the development of severe clinical forms of human strongyloidiasis. The diagnosis of this infection is primarily performed by parasitological techniques, but with low sensitivity. Serological techniques appear as an alternative, especially with heterologous antigens use. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0001706X183034
Publisher Site
http://dx.doi.org/10.1016/j.actatropica.2018.12.020DOI Listing
February 2019
17 Reads

Strongyloides stercoralis infection in imported and local dogs in Switzerland: from clinics to molecular genetics.

Parasitol Res 2019 Jan 14;118(1):255-266. Epub 2018 Dec 14.

Small Animal Clinic, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Strongyloides stercoralis is a worldwide-distributed intestinal nematode affecting mainly humans and dogs. Canine strongyloidosis is generally characterised by diarrhoea, malabsorption and bronchopneumonia, and may be fatal in cases of impaired immunity. In recent years, molecular and epidemiological studies suggested that host-adapted populations of S. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00436-018-6173-3
Publisher Site
http://dx.doi.org/10.1007/s00436-018-6173-3DOI Listing
January 2019
4 Reads

Coinfections between Persistent Parasitic Neglected Tropical Diseases and Viral Infections among Prisoners from Sub-Saharan Africa and Latin America.

J Trop Med 2018 6;2018:7218534. Epub 2018 Nov 6.

Division of Prison Health, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

In Swiss prisons, more than 70% of detained people are foreigners and over one-third originate from sub-Saharan Africa or Latin America. These two regions are endemic for various tropical diseases and viral infections, which persist after migration to nonendemic countries. Parasitic infections (schistosomiasis; strongyloidiasis) and cooccurrent viral infections (HIV, hepatitis B (HBV), and hepatitis C (HCV)) are especially of concern for clinical care but have been neglected in empirical research. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/jtm/2018/7218534/
Publisher Site
http://dx.doi.org/10.1155/2018/7218534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247427PMC
November 2018
6 Reads

Strongyloides venezuelensis infection augments arterial blood pressure in male wistar rats.

Acta Trop 2019 Feb 6;190:350-355. Epub 2018 Dec 6.

ICBS- Instituto de Ciências Biológicas e da Saúde, UFMT- Universidade Federal de Mato Grosso, Barra do Garças, Mato Grosso, Brazil. Electronic address:

Strongyloidiasis is an intestinal parasitosis that occurs in humans infected by Strongyloides stercoralis mostly. At its acute phase, symptoms like constipation, diarrhea and abdominal pain can be observed, but become asymptomatic for a long time, until an immunosuppression will start a hyperinfection and the dissemination of the disease, prevalent on the elderly population in tropical countries. Ivermectina treatment is the currently choice for this disease, due to its great efficacy and the results reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.actatropica.2018.12.007DOI Listing
February 2019
2 Reads

Seroepidemiological aspects of human infection by Strongyloides stercoralis in Alfenas, southern Minas Gerais, Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):855-859

Laboratório de Diagnóstico de Parasitoses, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.

Introduction: In most Strongyloides stercoralis infected individuals, nematoidosis occurs asymptomatically, but in immunocompromised patients, it can cause hyperinfection. Serological techniques seem to be a good alternative for detecting this parasite.

Methods: The frequency of seropositivity for strongyloidiasis in Alfenas, MG, was estimated using the enzyme linked immunosorbent assay on blood samples, between May and August of 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0090-2018DOI Listing
February 2019
3 Reads

Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome.

Case Rep Infect Dis 2018 28;2018:6870768. Epub 2018 Oct 28.

Department of Medicine, Poona Hospital and Research Center, Pune, Maharashtra, India.

Parasitic infections such as and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/criid/2018/6870768/
Publisher Site
http://dx.doi.org/10.1155/2018/6870768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230409PMC
October 2018
9 Reads

Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti.

PLoS Negl Trop Dis 2018 11 29;12(11):e0006992. Epub 2018 Nov 29.

Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

Infections with helminth parasites are controlled by a concerted action of innate and adaptive effector cells in the frame of a type 2 immune response. Basophils are innate effector cells that may also contribute to the initiation and amplification of adaptive immune responses. Here, we use constitutively basophil-deficient Mcpt8-Cre mice to analyze the impact of basophils during initiation and execution of the protective type 2 responses to both, a primary infection and a challenge infection of immune mice with the helminth parasite Strongyloides ratti. Read More

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pntd.0006992
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0006992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289456PMC
November 2018
8 Reads

High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study.

PLoS Negl Trop Dis 2018 11 29;12(11):e0007010. Epub 2018 Nov 29.

ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.

Background: Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, using our institution's serum bank. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0007010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289465PMC
November 2018
3 Reads

Gastroduodenal involvement in disseminated strongyloidiasis.

JGH Open 2018 Apr 22;2(2):75-76. Epub 2018 Feb 22.

Department of Gastroenterology Kobe City Medical Center General Hospital Kobe Japan.

Here, we report the case of a 57-year-old Peruvian man on long-term corticosteroid therapy for a drug allergy and proton pump inhibitors for chronic dyspepsia symptoms. Upper gastrointestinal endoscopy showed multiple white granular lesions and widespread erosions in the stomach. Our findings indicate that gastric strongyloidiasis should be carefully considered in high-risk patients even if endoscopic findings are nonspecific. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jgh3.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206995PMC
April 2018
2 Reads

Serodiagnosis and early detection of Strongyloides stercoralis infection.

J Microbiol Immunol Infect 2018 Oct 11. Epub 2018 Oct 11.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia. Electronic address:

Strongyloidiasis is a major neglected tropical disease with the potential of causing lifelong infection and mortality. One of the ways for effective control of this disease is developing improved diagnostics, particularly using serological approaches. A serological test can achieve high diagnostic sensitivity and specificity, has the potential for point-of-care translation, and can be used as a screening tool for early detection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmii.2018.10.001DOI Listing
October 2018
2 Reads

Efficacy of ivermectin to control Strongyloides stercoralis infection in sheltered dogs.

Acta Trop 2019 Feb 19;190:204-209. Epub 2018 Nov 19.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy; Dipartimento di Diagnostica e Sanità pubblica, Università degli Studi di Verona, Italy.

In dogs, information on treatments against S. stercoralis infection is rare and anecdotal. The aim of the present work was to evaluate the treatment outcome of S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.actatropica.2018.11.014DOI Listing
February 2019
22 Reads

Streptococcus pyogenes bacteremia and toxic shock syndrome related to Strongyloides stercoralis hyperinfection: a case report.

J Med Case Rep 2018 Nov 22;12(1):346. Epub 2018 Nov 22.

Reference Parasitology Laboratory, Central Laboratories, Public Health Services, Ministry of Health, Jerusalem, Israel.

Background: We describe a patient with Strongyloides stercoralis hyperinfection associated with Streptococcus pyogenes and with streptococcal toxic shock syndrome. To the best of our knowledge this association has not been previously described.

Case Presentation: A 78 year-old Israeli man, who was born in Iraq but lived in Israel for 66 years, presented with multi-organ failure including acute kidney and hepatic injury, coagulopathy, and lactic acidosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13256-018-1885-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249898PMC
November 2018
18 Reads

Strongyloidiasis and Culture-Negative Suppurative Meningitis, Japan, 1993-2015.

Emerg Infect Dis 2018 12;24(12):2378-2380

Community-acquired Enterobacteriaceae infection and culture-negative meningitis are rare and atypical subtypes of meningitis in adults. Of 37 patients who had atypical suppurative meningitis during 1993-2015 in Okinawa, Japan, 54.5% had strongyloidiasis, of which 9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3201/eid2412.180375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256405PMC
December 2018
2 Reads

Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem.

Am J Trop Med Hyg 2019 Jan;100(1):130-134

Division of Infectious Diseases, Department of Medicine, St. Joseph's Health Centre, Toronto, Canada.

Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the CNS sample in one case. Read More

View Article

Download full-text PDF

Source
http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0813
Publisher Site
http://dx.doi.org/10.4269/ajtmh.18-0813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335887PMC
January 2019
32 Reads

Fatal strongyloidiasis after corticosteroid therapy for presumed chronic obstructive pulmonary disease.

JMM Case Rep 2018 Sep 11;5(9):e005165. Epub 2018 Sep 11.

Sumeru Hospital, Dhapakhel, Lalitpur, Nepal.

Introduction: Strongyloidiasis is a neglected tropical disease with global prevalence. Under some cases of immune suppression (especially with corticosteroid administration), the nematode involved disseminates, leading to an amplified, possibly lethal hyper-infection syndrome.

Case Presentation: A 56-year-old Nepalese man presenting with chief complaints of nausea, vomiting, joint pain and abdominal cramps was admitted to Sumeru Hospital. Read More

View Article

Download full-text PDF

Source
http://www.microbiologyresearch.org/content/journal/jmmcr/10
Publisher Site
http://dx.doi.org/10.1099/jmmcr.0.005165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230759PMC
September 2018
14 Reads