Rev Gastroenterol Peru 2017 Apr-Jun;37(2):169-172

Hospital Nacional Cayetano Heredia. Lima, Perú; Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia. Lima, Perú.

Infection by the Human T- Lymphotropic virus I (HTLV-1) causes Adult T cell Leukemia-lymphoma (ATLL), being the duodenal involvement rare. Commonly, patients co-infected with HTLV-1 and Strongyloides stercoralis are seen due to the lack of TH2 response found on these patients. We describe a 48-year- old woman, from the jungle of Peru, with a family history of HTLV-1 infection, who presented with a History of chronic diarrhea and weight loss. Read More

Parasit Vectors 2017 Jul 20;10(1):345. Epub 2017 Jul 20.

Department of Veterinary Medicine, University of Bari, 70010, Valenzano, Bari, Italy.

Background: The increasing number of reports of human infections by Strongyloides stercoralis from a range of European countries over the last 20 years has spurred the interest of the scientific community towards this parasite and, in particular, towards the role that infections of canine hosts may play in the epidemiology of human disease. Data on the epidemiology of canine strongyloidiasis is currently limited, most likely because of the inherent limitations of current diagnostic methods.

Methods: Faecal samples were collected directly from the rectal ampulla of 272 animals of varying age and both genders living in Apulia, southern Italy. Read More

Int Med Case Rep J 2017 27;10:219-222. Epub 2017 Jun 27.

Internal Medicine, Wake Forest Baptist Health, Winston Salem, NC, USA.

This is a case of strongyloidiasis showing colon enhancement on a computerized tomography (CT) scan. The patient presented with chief complaints of diarrhea and abdominal pain. She gave a history of recent travel to El Salvador and her stool was positive for Strongyloides stercoralis. Read More

Front Cell Infect Microbiol 2017 20;7:261. Epub 2017 Jun 20.

Department of Veterinary Medicine, Institute of Immunology, Freie Universität BerlinBerlin, Germany.

Infections by the soil-transmitted threadworm Strongyloides stercoralis affect 30-100 million people worldwide, predominantly in tropic and sub-tropic regions. Here we assessed the T helper cell phenotypes in threadworm-infected patients and experimental murine infections with focus on CD4(+) T cells co-expressing markers of Th2 and Th1 differentiation. We show that mice infected with the close relative S. Read More

Zoonoses Public Health 2017 Jul 2. Epub 2017 Jul 2.

Department of Botany, Academy of Natural Sciences, Philadelphia, PA, USA.

Strongyloides and other soil-transmitted helminths represent a severely under-recognized zoonotic public health risk, especially in North American cities. They are present throughout North America, including in urban areas, causing morbidity and mortality in human and non-human animals. Epidemiological "masking" of strongyloidiasis due to overlapping symptoms with other systemic diseases, including allergies, and diagnostic limitations complicate our understanding of the epidemiological extent of this disease, and auto-infection allows long-term persistence of individual infections. Read More

Am J Med Sci 2017 Jun 26;353(6):593-596. Epub 2016 May 26.

Department of Medicine, Division of Internal Medicine, University of Mississippi Medical Center, Jackson, Mississippi.

We report the successful treatment of an HIV-infected patient with progressive strongyloidiasis as a component of immune reconstitution disease and a review of the literature on this topic. In our experience, pre- and post-antiretroviral therapy intestinal biopsies support a novel mechanism of immune reconstitution disease to Strongyloides stercoralis. We conclude that extended, dual antihelminthic therapy and temporary discontinuation of antiretroviral therapy may be effective in similar patients. Read More

Turk J Med Sci 2017 Jun 12;47(3):897-901. Epub 2017 Jun 12.

Department of Infectious Diseases, Medical School, Ege University, İzmir, Turkey.

Background/aim: Strongyloides stercoralis causes life-threatening hyperinfection or disseminated strongyloidiasis in immunocompromised patients such as HIV-positive, organ transplantation, and cancer patients. This study investigated the presence of strongyloidiasis in immunocompromised patients for the first time in Turkey.

Materials And Methods: Serum and stool samples were collected from 108 patients (25. Read More

N Engl J Med 2017 Jun;376(24):2376

University of Texas Health Science Center at San Antonio, San Antonio, TX

Clin Med (Lond) 2017 Jun;17(3):248-250

East Sussex Healthcare NHS Trust, St Leonards-on-sea, UK.

A 59-year-old lady presented with a 1-week history of orthopnoea, paroxysmal nocturnal dyspnoea, night sweats and a productive cough. She had no recent history of travel. Transthoracic echocardiogram revealed preserved left ventricular systolic function with abnormal pericardial thickening and restrictive left ventricular filling consistent with pericardial constriction. Read More

Curr Opin Organ Transplant 2017 Aug;22(4):336-344

aDepartment of Surgery, Division of Surgical Critical Care bSherrie & Alan Conover Center for Liver Disease & Transplantation, Houston Methodist Hospital, Houston, Texas, USA.

Purpose Of Review: Strongyloidiasis is a parasitic infection affecting millions of people worldwide. Complications of infection are strongly associated with alcoholism, immunosuppression, and organ transplantation. Delayed diagnosis results in hyperinfection syndrome and disseminated strongyloidiasis leading to mortality rates approaching 80%. Read More

Parasitol Res 2017 Jul 15;116(7):2047-2051. Epub 2017 May 15.

Department of Parasitology, University of Vila Velha-ES, Vila Velha, ES, Brazil.

Strongyloidiasis is the most clinically important disease among the infections caused by geohelminths, seeing that this parasite can cause autoinfection. The use of nematophagous fungi like Duddingtonia flagrans, that have predation action on eggs and infecciososas forms of helminths, emerges as an alternative method for environmental control. For this reason, analyzing the viability of larvae and eggs of Strongyloides venezuelensis and the action of Duddingtonia flagrans AC001 in vermiculite, as well as the action of the nematophagous fungi in different growth stages, is important to elaborate and define the best culture conditions that favor the activity of the fungus. Read More

PLoS Negl Trop Dis 2017 May 15;11(5):e0005607. Epub 2017 May 15.

Menzies School of Health Research, Charles Darwin University, Darwin, Australia.

Background: Strongyloides seroprevalence is hyper-endemic in many Australian Aboriginal and Torres Strait Islander communities, ranging from 35-60%. We report the impact on Strongyloides seroprevalence after two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community.

Methods: Utilizing a before and after study design, we measured Strongyloides seroprevalence through population census with sequential MDAs at baseline and month 12. Read More

Parasitol Res 2017 Jul 12;116(7):1917-1923. Epub 2017 May 12.

Research and Diagnostic Center for Emerging Infectious Diseases, Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand.

The parasitic nematodes, Strongyloides stercoralis and Strongyloides fuelleborni, can infect humans and non-human primates. We amplified and sequenced a portion of the 18S ribosomal RNA gene (rRNA) and of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene of Strongyloides from humans in the study area in Thailand, where people have frequent contact with long-tailed macaques. Fresh stool samples were obtained from 213 people and were examined using the agar plate culture method. Read More

Parasitol Res 2017 Jul 10;116(7):2027-2029. Epub 2017 May 10.

Centre for Tropical Diseases, Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024, Negrar, Verona, Italy.

Strongyloides stercoralis can cause severe infection both in humans and dogs. Coproparasitological examination has low sensitivity for the diagnosis of this parasite; hence, different diagnostic techniques have been implemented. However, serology and molecular methods have been assessed almost exclusively in humans. Read More

Clin Med Insights Case Rep 2017 8;10:1179547616684828. Epub 2017 Feb 8.

Internal Medicine Residency, St. Elizabeth's Medical Center, Brighton, MA, USA.

Chronic strongyloidiasis is an infection of the tropical regions, caused by the nematode Strongyloides stercoralis. In the United States, patients are typically immigrants. The very long asymptomatic phase followed by the clinical presentation of the disease mimics asthma, chronic obstructive pulmonary disease (COPD), or inflammatory bowel disease (IBD) as in this case report. Read More

BMC Infect Dis 2017 May 2;17(1):320. Epub 2017 May 2.

Department of Infectious Diseases, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.

Background: Strongyloidiasis is a chronic parasitic infection caused by Strongyloides stercoralis. Severe cases such as, hyperinfection syndrome (HS) and disseminated strongyloidiasis (DS), can involve pulmonary manifestations. These manifestations frequently aid the diagnosis of strongyloidiasis. Read More

PLoS Negl Trop Dis 2017 May 1;11(5):e0005569. Epub 2017 May 1.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.

Background / Objectives: Helminth infections are known to influence T cell responses in latent tuberculosis (LTBI). Whether helminth infections also modulate B cell responses in helminth-tuberculosis co-infection is not known.

Methods: We assessed Mycobacterium tuberculosis (Mtb)-antigen specific IgM and IgG levels, circulating levels of the B cell growth factors, BAFF and APRIL and the absolute numbers of the various B cell subsets in individuals with LTBI, LTBI with coincident Strongyloides stercoralis (Ss) infection (LTBI/Ss) and in those with Ss infection alone (Ss). Read More

Parasitol Res 2017 Jun 29;116(6):1687-1693. Epub 2017 Apr 29.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Strongyloides stercoralis is an intestinal helminth that infects people worldwide. Hyperinfection or disseminated human strongyloidiasis can involve vital organs, leading to lethal outcomes. We analyzed immunoproteomics of antigenic spots, derived from S. Read More

Radiol Bras 2017 Mar-Apr;50(2):137-138

Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brazil.

J La State Med Soc 2017 Mar-Apr;169(2):51. Epub 2017 Apr 15.

Department of Internal Medicine, Tulane Health Sciences Center in New Orleans, LA.

Case: A 48 year-old man with no past medical history was sent to our emergency department (ED); from a primary care clinic for hypertensive urgency of 200/130. The man reported an intermittent non-productive cough of approximately one year's duration and worsening dyspnea on exertion and orthopnea over the last month with lower extremity swelling. Of note, he emigrated from Honduras twenty years ago. Read More

Rev Chilena Infectol 2017 Feb;34(1):47-53

Centro de Pesquisas Aggeu Magalhães, Departamento de Parasitología, Serviço de Referência Nacional em Filarioses, Fundação Oswaldo Cruz, Pernambuco, Brasil.

The strongyloidiasis is a parasitic disease that poses as a serious public health problem, mainly in tropical and subtropical countries. Over the years, some conditions, such as advances in corticosteroid treatment and immunosuppressive diseases, have improved not only the increase in cases of strongyloidiasis, but also the emergence of severe forms of the disease and / or deaths. For these reasons, the objective of this study is to make a critical analysis of the occurrence of strongyloidiasis in patients with comorbidities, describing clinical and epidemiological characteristics associated with these diseases that can highlight the importance of monitoring this parasitosis in most susceptible groups. Read More

Rev Inst Med Trop Sao Paulo 2017 Apr 3;59:e7. Epub 2017 Apr 3.

Universidade Federal de Goiás, Laboratório de Parasitologia, Jataí, Goiás, Brazil.

Latex from Carica papaya is rich in bioactive compounds, especially papain, which may help to control parasitic diseases. This study evaluated the efficacy of latex from C. papaya and purified papain against Strongyloides venezuelensis. Read More

Diagn Microbiol Infect Dis 2017 Jun 14;88(2):168-170. Epub 2017 Mar 14.

Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place 1090, New York, NY, 10029.

Strongyloides stercoralis is a unique intestinal nematode with the ability to replicate and complete its life cycle without leaving the host. We report a fatal case of Strongyloides hyperinfection syndrome in a patient who had persistent eosinophilia for several years but negative Strongyloides serology. Our case suggests that ELISA serologies cannot solely be relied upon to diagnose Strongyloides stercoralis infection; history and clinical judgment remain crucial to this diagnosis. Read More

Germs 2017 Mar 1;7(1):28-31. Epub 2017 Mar 1.

MD, FIDSA, Senior Consultant, Institute of Infectious Diseases, Apollo Hospitals, 2A Rajam Mansion, 4 Luz Ave 4th St, Chennai, 600004, Tamil Nadu, India.

Introduction: Strongyloidiasis can cause hyperinfection or disseminated infection in an immunocompromised host, and is an important factor linked to enterococcal bacteremia and meningitis.

Case Reports: We report two cases highlighting the importance of suspecting Strongyloides hyperinfection syndrome in patients with enterococcal meningitis.

Conclusion: Our cases highlight the importance of suspecting Strongyloides hyperinfection syndrome in cases of community acquired enterococcal bacteremia and meningitis. Read More

BMJ Case Rep 2017 Mar 22;2017. Epub 2017 Mar 22.

Department of Medicine, George Washington University, Washington, DC, USA.

Strongyloides stercoralis infection is usually asymptomatic but can result in a hyperinfection syndrome, most commonly triggered by acquired or iatrogenic immunosuppression. Here, we present a case of a man aged 60 years originally from a strongyloides endemic area with a medical history of alcohol abuse who presents with strongyloides hyperinfection syndrome (SHS) complicated by partial small bowel obstruction, pulmonary haemorrhage, large bandemia without eosinophilia and cardiac arrest resulting in death. This case is notable for the presence of bandemia and absence of eosinophilia, lack of historical risk factors for hyperinfection, specifically corticosteroid immunosuppressants, and dramatic decline in clinical status which ultimately resulted in the patient's death. Read More

Infect Dis Poverty 2017 Mar 23;6(1):65. Epub 2017 Mar 23.

National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention, Shanghai, China.

Schistosomiasis, one of the 17 neglected tropical diseases listed by the World Health Organization, presents a substantial public health and economic burden. Of the 261 million people requiring preventive chemotherapy for schistosomiasis in 2013, 92% of them lived in sub-Saharan Africa and only 12.7% received preventive chemotherapy. Read More

Infect Immun 2017 May 21;85(5). Epub 2017 Apr 21.

Department of Pathology, Stanford University School of Medicine, Stanford, California, USA

There is evidence that mast cells, basophils, and IgE can contribute to immune responses to parasites; however, the relative levels of importance of these effector elements in parasite immunity are not fully understood. Previous work in Il3-deficient and c-kit mutant Kit(W/W-v) mice indicated that interleukin-3 and c-Kit contribute to expulsion of the intestinal nematode Strongyloides venezuelensis during primary infection. Our findings in mast cell-deficient Kit(W-sh/W-sh) mice and two types of mast cell-deficient mice that have normal c-kit ("Hello Kitty" and MasTRECK mice) confirmed prior work in Kit(W/W-v) mice that suggested that mast cells play an important role in S. Read More

J Eur Acad Dermatol Venereol 2017 Mar 6. Epub 2017 Mar 6.

Dermatology Department, Faculty of Medicine of ABC, São Paulo, Brazil.

Clin Microbiol Infect 2017 May 1;23(5):335.e1-335.e5. Epub 2017 Mar 1.

Infectious Diseases Unit, Department of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, Alma Mater Studiorum University of Bologna, Bologna, Italy.

Objective: This multicentre cross-sectional study aims to estimate the prevalence of five neglected tropical diseases (Chagas disease, filariasis, schistosomiasis, strongyloidiasis and toxocariasis) among immigrants accessing health care facilities in five Italian cities (Bologna, Brescia, Florence, Rome, Verona).

Methods: Individuals underwent a different set of serological tests, according to country of origin and presence of eosinophilia. Seropositive patients were treated and further followed up. Read More

Transplant Proc 2017 Mar;49(2):373-377

Adult Stem Cell Transplant Program, The University of Miami Miller School of Medicine & Sylvester Comprehensive Cancer Center, Miami, Florida, USA.

Syndrome of inappropriate anti-diuretic hormone (SIADH) has been reported to be associated with systemic Strongyloides stercoralis. Here, we report a case of a stem cell transplant (SCT) recipient who developed severe SIADH secondary to systemic S Stercoralis. The SIADH resolved quickly after treating the systemic S Stercoralis with ivermectin. Read More

J Parasitol Res 2017 22;2017:5056314. Epub 2017 Jan 22.

Department of Animal Biology, Post-Graduation Program in Animal Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, SP, Brazil.

Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives. Read More

BMJ Case Rep 2017 Feb 8;2017. Epub 2017 Feb 8.

Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

PLoS Negl Trop Dis 2017 Feb 8;11(2):e0005213. Epub 2017 Feb 8.

London School of Hygiene & Tropical Medicine, London, United Kingdom.

Background: Chronic parasitic infections are associated with active immunomodulation which may include by-stander effects on unrelated antigens. It has been suggested that pre-natal exposure to parasitic infections in the mother impacts immunological development in the fetus and hence the offspring's response to vaccines, and that control of parasitic infection among pregnant women will therefore be beneficial.

Methodology/principal Findings: We used new data from the Entebbe Mother and Baby Study, a trial of anthelminthic treatment during pregnancy conducted in Uganda, to further investigate this hypothesis. Read More

Clin Neuropathol 2017 May/Jun;36 (2017)(3):154-155

Iran J Parasitol 2016 Oct-Dec;11(4):527-533

Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran; Research Center for Fascioliasis and Parasitic Diseases, Guilan University of Medical Sciences, Rasht, Iran.

Background: We aimed to determine the status of strongyloidiasis in mentally disabled population in the institutional places in Rasht City, the capital of Guilan Province, northern Iran.

Methods: This cross-sectional study was conducted in 8 institutions for mentally retarded population in Rasht in 2013. Before collecting the samples, a questionnaire was filled out for each participant by an expert person. Read More

Iran J Parasitol 2016 Jul-Sep;11(3):411-416

Dept. of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Strongyloidiasis is a frequent misdiagnosed parasitic infection in the world that caused by Strongyloides stercoralis. In Iran, the disease is predominantly reported from warm and humid climate provinces. The patient was a 54-yr-old man, originated from Khuzestan Province with a history of pemphigus and diabetes that was treated with high-dose of corticosteroid drugs before admission in a non-private hospital in Shiraz, Iran in 2014. Read More

Parasitol Res 2017 Apr 26;116(4):1159-1163. Epub 2017 Jan 26.

Department of Parasitology of Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.

Strongyloidiasis is one of the neglected tropical diseases caused by infection with the nematode Strongyloides genus and distributed worldwide. Strongyloidiasis can be fatal in immunosuppressed patients induced hyperinfection or disseminated strongyloidiasis. Unfortunately, until now, due to the unspecific clinical symptom in infected individuals and the low sensitivity diagnosis of strongyloidiasis, many patients were misdiagnosed every year. Read More

Rev Chilena Infectol 2016 Oct;33(5):589-592

Universidad Técnica de Ambato, Ecuador.

Intestinal parasites are a common pathology in the pediatric practice, constituting a major public health problem. Currently their epidemiology, especially in countries like Ecuador where there are populations and communities where health services are scarce or difficult to access. We report the case of a child with chronic grade 3 malnutrition, from Sarayacu province of Pastaza, Ecuador an endemic area in several parasitosis. Read More

Rev Chilena Infectol 2016 Oct;33(5):584-588

Facultad de Salud, Universidad Santiago de Cali, Colombia.

Strongyloidiasis is an infection caused by the parasite Strongyloides stercoralis, which can be asymptomatic and means a high morbidity and mortality in immunocompromised hosts, severe malnutrition and coinfection with HTLV-1 virus. The parasite has the potential to produce and multiply internal autoinfection in humans, thus an hyperinfection can be developed. A case of pulmonary infection by this parasite is presented in this study, infection which advanced into a respiratory failure and required mechanical ventilation and hemodynamic support in an intensive care unit. Read More

J Helminthol 2017 Jan 23:1-5. Epub 2017 Jan 23.

Department of Parasitology,National Centre for Microbiology,Instituto de Salud Carlos III,Majadahonda,Madrid 28220,Spain.

Strongyloidiasis is usually an asymptomatic disease in immunocompetent patients, caused by Strongyloides stercoralis. However, in immunocompromised patients it can produce a severe clinical profile. Therefore, a correct diagnosis is necessary in these cases and in those chronic asymptomatic patients. Read More

Biomed Res Int 2016 26;2016:4872473. Epub 2016 Dec 26.

Faculdade de Farmácia, Universidade Federal da Bahia, 40170115 Salvador, BA, Brazil.

The course of Strongyloides stercoralis infection is usually asymptomatic with a low discharge of rhabditoid larva in feces. However, the deleterious effects of alcohol consumption seem to enhance the susceptibility to infection, as shown by a fivefold higher strongyloidiasis frequency in alcoholics than in nonalcoholics. Moreover, the association between S. Read More

Trans R Soc Trop Med Hyg 2017 Jan 18. Epub 2017 Jan 18.

Department of Virology, Parasitology and Immunology, Ghent University, Faculty of Veterinary Medicine, Salisburylaan 133, B-9820 Merelbeke, Belgium

Background: The diagnosis of soil-transmitted helminths (STHs; Ascaris, Trichuris and hookworms) is traditionally based on the demonstration of eggs in stool using microscopic techniques. While molecular techniques are more appropriate to speciate STH species they are seldom applied. In this study we speciated STH eggs from stool using molecular techniques to gain insights into the distribution of both human and animal STH species in the human host. Read More

Iran J Parasitol 2016 Apr-Jun;11(2):279-283

Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Strongyloides stercoralis is a soil-transmitted helminth (STH) widespread in various part of the world. A 78-yr-old peasant diabetic female from Mazandaran Province northern Iran, was admitted to Infection Department of the Razi Hospital in city of Qaemshahr, north of Iran complaining about abdominal skin rash, pruritus, itching, anorexia, nausea, vomiting, dysuria and cough. This patient had cutaneous migration effects of S. Read More

BMJ Case Rep 2017 Jan 16;2017. Epub 2017 Jan 16.

Department of Pulmonary and Critical Care, University of Missouri-Kansas City, Kansas City, Missouri, USA.

Immunocompromised patients have high risk of infections from bacteria, viruses, fungi and parasites. One of these infections is those caused by Strongyloides stercoralis Immunocompromised patients are at risk of hyperinfection syndrome which is characterised with more systemic manifestation and a higher risk of morbidity and mortality. This can be complicated by coinfection with enteric organisms, specifically Gram-negative. Read More

BMC Infect Dis 2017 Jan 13;17(1):68. Epub 2017 Jan 13.

Department of Medical Laboratory Science, Arba Minch University, Arba Minch, Ethiopia.

Background: Helminths affect the outcome of tuberculosis by shifting cell mediated immune response to humoral and by total suppression of the host immune system. On the reverse, Mycobacterium infection favors immune escape of helminths. Therefore assessing helminth co-infection rate and predisposing factors in tuberculosis patients is mandatory to set strategies for better case management. Read More

Parasitol Res 2017 Mar 12;116(3):1071-1074. Epub 2017 Jan 12.

Núcleo de Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos 1468, Vitória, ES, CEP: 29043-900, Brazil.

An increased number of regulatory T (Treg) cells has been reported in patients with HTLV-1 and Strongyloides stercoralis co-infection, suggesting the contribution of these cells to worm survival. As Strongyloides infections have been found to be highly prevalent in chronic alcoholics, we investigated the effect of abusive ethanol ingestion on the induction of Treg cells in alcoholic patients with Strongyloides infection. Treg cells were assessed by flow cytometry in the peripheral blood of 12 healthy non-alcoholic (control) and 14 alcoholic patients (alcoholic) without Strongyloides infection and five non-alcoholics (controlSs) and five chronic alcoholics (alcoholSs) with Strongyloides infection. Read More

Parasitol Res 2017 Mar 10;116(3):891-900. Epub 2017 Jan 10.

Department of Epizootiology and Parasitology, University of Veterinary Medicine and Pharmacy, Komenského 73, 041 81, Košice, Slovak Republic.

A comparative study was carried out to evaluate the Strongyloides stercoralis infections in children and dogs inside and outside the segregated settlement in Medzev, Eastern Slovakia, and a survey of the soil within the settlement was included. Applying the Koga agar plate (KAP) culture method and microscopy examination of stool samples collected from 60 Roma and 21 nonRoma children, no larvae of S. stercoralis were detected but eggs of three nematodes (Ascaris lumbricoides, Trichuris trichiura, and Enterobius vermicularis) and cysts of two protozoan endoparasites (Giardia duodenalis and Cryptosporidium spp. Read More

Parasitology 2017 May 11;144(6):812-816. Epub 2017 Jan 11.

Centre for Tropical Diseases,Sacro Cuore Don Calabria Hospital,Via Sempreboni 5,37024 Negrar,Verona,Italy.

Strongyloides stercoralis is a parasite that can cause death in immunocompromised people. A proper diagnosis is hence essential. The real-time polymerase-chain reaction (RT-PCR) is a novel, promising diagnostic method, that detects the DNA of the parasite in stool samples. Read More