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    Case Report: A Case of Recurrent Strongyloides stercoralis Colitis in a Patient with Multiple Myeloma.
    Am J Trop Med Hyg 2017 Nov;97(5):1619-1622
    Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio.
    Strongyloides stercoralis chronic infection is frequently subclinical and thus under-recognized, although its increasing prevalence in nonendemic regions has implications for immunocompromised hosts. We present a 75-year-old male with stage II multiple myeloma who presented with relapse of Strongyloides infection after initial treatment, negative surveillance testing, and subsequent resumption of chemotherapy for his multiple myeloma. The optimal regimen for secondary prophylaxis against recurrent infections is unknown. Read More

    Electroacupuncture in rats infected with Strongyloides venezuelensis: effects on gastrointestinal transit and parasitological measurements.
    Acupunct Med 2017 Nov 4. Epub 2017 Nov 4.
    Instituto de Ciências Biológicas e da Saúde, UFMT-Universidade Federal de Mato Grosso, Barra do Garças, Mato Grosso, Brazil.
    Objective: To investigate the effects of electroacupuncture (EA) at ST36 and CV12 on gastrointestinal transit and parasitological measurements during Strongyloides venezuelensis infection in rats.

    Design: Rats were infected with S. venezuelensis and allocated to one of three groups that were infected and remaineduntreated (SV group, n=8), infected and treated with EA at CV12 (SV+CV12 group, n=8) or infected and treated with EA at ST36 (SV+ST36 group, n=8). Read More

    Strongyloides stercoralis is associated with significant morbidity in rural Cambodia, including stunting in children.
    PLoS Negl Trop Dis 2017 Oct 23;11(10):e0005685. Epub 2017 Oct 23.
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
    Background: Strongyloides stercoralis is a soil-transmitted nematode that can replicate within its host, leading to long-lasting and potentially fatal infections. It is ubiquitous and highly prevalent in Cambodia. The extent of morbidity associated with S. Read More

    Strongyloides stercoralis seroprevalence in Vietnam.
    Epidemiol Infect 2017 Nov 17;145(15):3214-3218. Epub 2017 Oct 17.
    Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme,Hanoi,Vietnam.
    Strongyloidiasis is a neglected tropical disease caused by the roundworm Strongyloides stercoralis affecting 30-100 million people worldwide. Many Southeast-Asian countries report a high prevalence of S. stercoralis infection, but there are little data from Vietnam. Read More

    Albendazole and ivermectin for the control of soil-transmitted helminths in an area with high prevalence of Strongyloides stercoralis and hookworm in northwestern Argentina: A community-based pragmatic study.
    PLoS Negl Trop Dis 2017 Oct 9;11(10):e0006003. Epub 2017 Oct 9.
    Instituto de Investigaciones en Enfermedades Tropicales, Universidad Nacional de Salta-Sede Regional Orán, San Ramón de la Nueva Orán, Salta, Argentina.
    Background: Recommendations for soil-transmitted helminth (STH) control give a key role to deworming of school and pre-school age children with albendazole or mebendazole; which might be insufficient to achieve adequate control, particularly against Strongyloides stercoralis. The impact of preventive chemotherapy (PC) against STH morbidity is still incompletely understood. The aim of this study was to assess the effectiveness of a community-based program with albendazole and ivermectin in a high transmission setting for S. Read More

    A case of adenocarcinoma developed in the small intestine with chronic strongyloidiasis.
    Clin J Gastroenterol 2017 Oct 7. Epub 2017 Oct 7.
    Department of Surgical Pathology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, Japan.
    We experienced a case of intestinal strongyloidiasis complicated by jejunal carcinoma. A Japanese male in his 50s, who has a 7-year medical history of duodenal ulcers, complained of loss of appetite, nausea, vomiting and diarrhea. Computed tomography and gastroduodenal endoscopic examination revealed a stenosis of the duodenum. Read More

    Helminths as an alternative therapy for intestinal diseases.
    World J Gastroenterol 2017 Sep;23(33):6009-6015
    LIM 07-Laboratory of Experimental Clinical Gastroenterology, Department of Gastroenterology and Hepatology, Clínicas Hospital of University of São Paulo-HCFMUSP and, School of Medicine at the University of São Paulo, São Paulo 04023-062, Brazil.
    Animal models and clinical studies have shown that helminth infections exert immunomodulatory activity, altering intestinal permeability and providing a potential beneficial action on autoimmune and inflammatory disorders in human beings, such as inflammatory bowel disease (IBD) and celiac disease. This is consistent with the theory that intestinal microbiota is responsible for shaping human immunological responses. With the arrival of the immunobiologic era and the use of antibodies, we propose a distinctive pathway for treating patients with IBD and celiac disease. Read More

    Avidity as a criterion for diagnosis of human strongyloidiasis increases specificity of IgG ELISA.
    Diagn Microbiol Infect Dis 2017 Dec 26;89(4):262-264. Epub 2017 Aug 26.
    Departamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Paraná, Brazil. Electronic address:
    This study evaluates the inclusion of the IgG avidity index in ELISA to detect anti-Strongyloides stercoralis IgG. The ELISA index revealed 70% of specificity. With the inclusion of screening AI, specificity increased to 80%. Read More

    Seroprevalence of Strongyloides stercoralis infection among HTLV-I infected blood donors in Barcelona, Spain: A cross-sectional study.
    Acta Trop 2017 Dec 20;176:412-414. Epub 2017 Sep 20.
    Department of Infectious Diseases, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, PROSICS Barcelona, Barcelona, Spain.
    Strongyloides stercoralis infection in patients with HTLV-I infection may lead to severe clinical manifestations. The aim of the present study is to determine the seroprevalence of S. stercoralis infection among blood donors who tested positive for HTLV-I infection. Read More

    Seroepidemiological trend of strongyloidiasis in the Bolivian Chaco (1987-2013) in the absence of disease-specific control measures.
    Trop Med Int Health 2017 Nov 12;22(11):1457-1462. Epub 2017 Oct 12.
    Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
    Objectives: The prevalence of Strongyloides stercoralis infections is grossly underestimated because infections go mostly undetected, although they can persist for a lifetime due to the auto-infective cycle. In the Bolivian Chaco, the prevalence of soil-transmitted nematodes dropped dramatically in the past 25 years, but the mebendazole used for preventive chemotherapy has no effect on S. stercoralis. Read More

    An eleven-year retrospective hospital-based study of epidemiological data regarding human strongyloidiasis in northeast Thailand.
    BMC Infect Dis 2017 Sep 18;17(1):627. Epub 2017 Sep 18.
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
    Background: Human strongyloidiasis is a chronic and persistent gastrointestinal disease caused by infection with soil-transmitted helminths of the genus Strongyloides. The aim of this research was to obtain diagnostic prevalence regarding strongyloidiasis in northeast Thailand through a hospital-based study.

    Methods: Patients' demographic data and the results of stool examinations conducted using the formalin ethyl acetate concentration technique were collected from the parasitology laboratory records at Srinagarind Hospital in Khon Kaen, Thailand. Read More

    Strongyloid Hyperinfection in a Patient with Immunocompromised Chronic Kidney Disease.
    Indian J Nephrol 2017 Sep-Oct;27(5):389-391
    Department of Nephrology, Care Hospitals, Hyderabad, Telangana, India.
    Strongyloid hyperinfection is seen in immunocompromised individuals with underlying lung disease. The use of immunosuppressive drugs is an important risk factor. We report a case of IgA nephropathy with crescent, started on glucocorticoid and mycophenolate mofetil. Read More

    Prevention and assessment of infectious diseases among children and adult migrants arriving to the European Union/European Economic Association: a protocol for a suite of systematic reviews for public health and health systems.
    BMJ Open 2017 Sep 11;7(9):e014608. Epub 2017 Sep 11.
    Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
    Introduction: The European Centre for Disease Prevention and Control is developing evidence-based guidance for voluntary screening, treatment and vaccine prevention of infectious diseases for newly arriving migrants to the European Union/European Economic Area. The objective of this systematic review protocol is to guide the identification, appraisal and synthesis of the best available evidence on prevention and assessment of the following priority infectious diseases: tuberculosis, HIV, hepatitis B, hepatitis C, measles, mumps, rubella, diphtheria, tetanus, pertussis, poliomyelitis (polio), Haemophilus influenza disease, strongyloidiasis and schistosomiasis.

    Methods And Analysis: The search strategy will identify evidence from existing systematic reviews and then update the effectiveness and cost-effectiveness evidence using prospective trials, economic evaluations and/or recently published systematic reviews. Read More

    Colorectal Cancer Associated with Strongyloides stercoralis Colitis.
    ACG Case Rep J 2017 30;4:e104. Epub 2017 Aug 30.
    Department of Pathology, Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, Elmhurst, NY.
    Strongyloides stercoralis colitis is a severe but easily curable disease with a high mortality rate if left untreated. Strongyloidiasis can persist up to several decades and may lead to a chronic colitis similar to that seen in inflammatory bowel disease (IBD), and the two are often confused. Chronic colitis from IBD is associated with an increased risk of colorectal cancer, so it is plausible that chronic colitis from strongyloidiasis may carry a similar risk. Read More

    Modulation of CD4(+) and CD8(+) T Cell Function and Cytokine Responses in Strongyloides stercoralis Infection by Interleukin-27 (IL-27) and IL-37.
    Infect Immun 2017 Nov 18;85(11). Epub 2017 Oct 18.
    National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India
    Strongyloides stercoralis infection is associated with diminished antigen-specific Th1- and Th17-associated responses and enhanced Th2-associated responses. Interleukin-27 (IL-27) and IL-37 are two known anti-inflammatory cytokines that are highly expressed in S. stercoralis infection. Read More

    Strongyloides stercoralis infection increases the likelihood to detect Trypanosoma cruzi DNA in peripheral blood in Chagas disease patients.
    Trop Med Int Health 2017 Nov 20;22(11):1436-1441. Epub 2017 Sep 20.
    Department of Infectious Diseases, Vall d'Hebron University Hospital, PROSICS Barcelona, Universitat Autònoma de Barcelona, Barcelona, Spain.
    Objectives: In a previous study performed by our group, Strongyloides stercoralis infection in patients with Chagas disease was associated with higher proportion of Trypanosoma cruzi DNA detection in peripheral blood. The aim of the study was to confirm this association in a larger cohort of patients.

    Methods: Cross-sectional study of all patients with Chagas disease diagnosed from 2005 to 2015 during blood donation at the Catalan Blood Bank. Read More

    The changing aetiology of eosinophilia in migrants and returning travellers in the Hospital for Tropical Diseases, London 2002-2015: An observational study.
    J Infect 2017 Oct 24;75(4):301-308. Epub 2017 Aug 24.
    Infectious Diseases and Tropical Medicine, Hospital for Tropical Diseases, University College London Hospitals NHS Trust, UK. Electronic address:
    Introduction: Determining the cause of eosinophilia in patients returning from the tropics continues to present a diagnostic challenge. The history, symptoms and degree of eosinophilia are often poor predictors of eventual diagnosis, but helminths are an important cause. The current British Infection Association recommendations use travel history to guide investigation of eosinophilia. Read More

    Prevalence of Strongyloides stercoralis and Other Intestinal Parasite Infections in School Children in a Rural Area of Angola: A Cross-Sectional Study.
    Am J Trop Med Hyg 2017 Oct 18;97(4):1226-1231. Epub 2017 Aug 18.
    Department of Infectious Diseases, Vall d'Hebron University Hospital, PROSICS, Barcelona, Spain.
    Strongyloides stercoralis is widely distributed in the tropics and subtropics. The aim of this study was to determine the prevalence of S. stercoralis and other intestinal parasites and identify the risk factors for infection with S. Read More

    Different but overlapping populations of Strongyloides stercoralis in dogs and humans-Dogs as a possible source for zoonotic strongyloidiasis.
    PLoS Negl Trop Dis 2017 Aug 9;11(8):e0005752. Epub 2017 Aug 9.
    Department of Evolutionary Biology, Max-Planck-Institute for Developmental Biology, Tübingen, Germany.
    Strongyloidiasis is a much-neglected soil born helminthiasis caused by the nematode Strongyloides stercoralis. Human derived S. stercoralis can be maintained in dogs in the laboratory and this parasite has been reported to also occur in dogs in the wild. Read More

    Control of chronic Strongyloides stercoralis infection in an endemic community may be possible by pharmacological means alone: Results of a three-year cohort study.
    PLoS Negl Trop Dis 2017 Jul 31;11(7):e0005825. Epub 2017 Jul 31.
    Public Health Medicine, Centre for Chronic Disease Prevention, Australian Institute of Tropical Health and Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University Cairns, Smithfield, Australia.
    Objectives: To assess the effect of treatment with ivermectin on the prevalence of S. stercoralis infection in an Australian Aboriginal population over a three year period, and to assess the validity of using a lower ELISA cut-off in diagnosis.

    Methods: A three-year cohort study of 259 adult Australian Aboriginals living in a remote community in northern Australia. Read More

    Evidence-Based Guidelines for Screening and Management of Strongyloidiasis in Non-Endemic Countries.
    Am J Trop Med Hyg 2017 Sep 27;97(3):645-652. Epub 2017 Jul 27.
    Barcelona Institute for Global Health (ISGlobal-CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
    Strongyloidiasis is an intestinal parasitic infection becoming increasingly important outside endemic areas, not only because of the high prevalence found in migrant populations, but also because immunosuppressed patients may suffer a potentially fatal disseminated disease. The aim of these guidelines is to provide evidence-based guidance for screening and treatment of strongyloidiasis in non-endemic areas. A panel of experts focused on three main clinical questions (who should be screened and how, how to treat), and reviewed pertinent literature available in international databases of medical literature and in documents released by relevant organizations/societies. Read More

    A Case of Strongyloidiasis: An Immigrant Healthcare Worker Presenting with Fatigue and Weight Loss.
    Case Rep Infect Dis 2017 28;2017:6718284. Epub 2017 Jun 28.
    Kingsbrook Jewish Medical Center, Brooklyn, NY, USA.
    Background: Strongyloides stercoralis is an intestinal nematode parasite classified as a soil-transmitted helminth, endemic in tropical and subtropical regions. Strongyloides stercoralis can remain dormant for decades after the initial infection.

    Case: We describe a patient who was diagnosed with Strongyloides stercoralis infection three weeks after a left inguinal hernia repair and discuss approaches to prevention, diagnosis, and treatment. Read More

    [Duodenal Linphoma asociated to Strongyloides stercoralis infection. Two types of HTLV-1 infection].
    Rev Gastroenterol Peru 2017 Apr-Jun;37(2):169-172
    Hospital Nacional Cayetano Heredia. Lima, Perú; Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia. Lima, Perú.
    Infection by the Human T- Lymphotropic virus I (HTLV-1) causes Adult T cell Leukemia-lymphoma (ATLL), being the duodenal involvement rare. Commonly, patients co-infected with HTLV-1 and Strongyloides stercoralis are seen due to the lack of TH2 response found on these patients. We describe a 48-year- old woman, from the jungle of Peru, with a family history of HTLV-1 infection, who presented with a History of chronic diarrhea and weight loss. Read More

    Occurrence of strongyloidiasis in privately owned and sheltered dogs: clinical presentation and treatment outcome.
    Parasit Vectors 2017 Jul 20;10(1):345. Epub 2017 Jul 20.
    Department of Veterinary Medicine, University of Bari, 70010, Valenzano, Bari, Italy.
    Background: The increasing number of reports of human infections by Strongyloides stercoralis from a range of European countries over the last 20 years has spurred the interest of the scientific community towards this parasite and, in particular, towards the role that infections of canine hosts may play in the epidemiology of human disease. Data on the epidemiology of canine strongyloidiasis is currently limited, most likely because of the inherent limitations of current diagnostic methods.

    Methods: Faecal samples were collected directly from the rectal ampulla of 272 animals of varying age and both genders living in Apulia, southern Italy. Read More

    Side Benefits of Mass Drug Administration for Lymphatic Filariasis on Strongyloides stercoralis Prevalence on Pemba Island, Tanzania.
    Am J Trop Med Hyg 2017 Sep 19;97(3):681-683. Epub 2017 Jul 19.
    University of Basel, Basel, Switzerland.
    Strongyloides stercoralis, although endemic in many countries, is not included in helminth control programs. Few data are available on the prevalence and morbidity linked to this infection. We compared data from two studies conducted in 1998 and 2013 on Pemba Island, Tanzania, involving 525 and 509 schoolchildren, respectively. Read More

    Case report of a computerized tomography sign in Strongyloides stercoralis infection.
    Int Med Case Rep J 2017 27;10:219-222. Epub 2017 Jun 27.
    Internal Medicine, Wake Forest Baptist Health, Winston Salem, NC, USA.
    This is a case of strongyloidiasis showing colon enhancement on a computerized tomography (CT) scan. The patient presented with chief complaints of diarrhea and abdominal pain. She gave a history of recent travel to El Salvador and her stool was positive for Strongyloides stercoralis. Read More

    Serologic Monitoring of Public Health Interventions against Strongyloides stercoralis.
    Am J Trop Med Hyg 2017 Jul;97(1):166-172
    Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
    Northwestern Argentina is endemic for soil-transmitted helminths, and annual deworming programs are carried out in prioritized areas. High prevalence of Strongyloides stercoralis was reported in this area; therefore, control programs including ivermectin are being evaluated. The NIE-enzyme linked immunosorbent assay (ELISA) was used for this purpose. Read More

    Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells.
    Front Cell Infect Microbiol 2017 20;7:261. Epub 2017 Jun 20.
    Department of Veterinary Medicine, Institute of Immunology, Freie Universität BerlinBerlin, Germany.
    Infections by the soil-transmitted threadworm Strongyloides stercoralis affect 30-100 million people worldwide, predominantly in tropic and sub-tropic regions. Here we assessed the T helper cell phenotypes in threadworm-infected patients and experimental murine infections with focus on CD4(+) T cells co-expressing markers of Th2 and Th1 differentiation. We show that mice infected with the close relative S. Read More

    The severely under-recognized public health risk of strongyloidiasis in North American cities-A One Health approach.
    Zoonoses Public Health 2017 Dec 2;64(8):579-588. Epub 2017 Jul 2.
    Department of Botany, Academy of Natural Sciences, Philadelphia, PA, USA.
    Strongyloides and other soil-transmitted helminths represent a severely under-recognized zoonotic public health risk, especially in North American cities. They are present throughout North America, including in urban areas, causing morbidity and mortality in human and non-human animals. Epidemiological "masking" of strongyloidiasis due to overlapping symptoms with other systemic diseases, including allergies, and diagnostic limitations complicate our understanding of the epidemiological extent of this disease, and auto-infection allows long-term persistence of individual infections. Read More

    Novel Findings in HIV, Immune Reconstitution Disease and Strongyloides stercoralis Infection.
    Am J Med Sci 2017 Jun 26;353(6):593-596. Epub 2016 May 26.
    Department of Medicine, Division of Internal Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
    We report the successful treatment of an HIV-infected patient with progressive strongyloidiasis as a component of immune reconstitution disease and a review of the literature on this topic. In our experience, pre- and post-antiretroviral therapy intestinal biopsies support a novel mechanism of immune reconstitution disease to Strongyloides stercoralis. We conclude that extended, dual antihelminthic therapy and temporary discontinuation of antiretroviral therapy may be effective in similar patients. Read More

    Screening of immunocompromised patients at risk of strongyloidiasis in western Turkey using ELISA and real-time PCR.
    Turk J Med Sci 2017 Jun 12;47(3):897-901. Epub 2017 Jun 12.
    Department of Infectious Diseases, Medical School, Ege University, İzmir, Turkey.
    Background/aim: Strongyloides stercoralis causes life-threatening hyperinfection or disseminated strongyloidiasis in immunocompromised patients such as HIV-positive, organ transplantation, and cancer patients. This study investigated the presence of strongyloidiasis in immunocompromised patients for the first time in Turkey.

    Materials And Methods: Serum and stool samples were collected from 108 patients (25. Read More

    A clinical enigma of ongoing constrictive pericarditis.
    Clin Med (Lond) 2017 Jun;17(3):248-250
    East Sussex Healthcare NHS Trust, St Leonards-on-sea, UK.
    A 59-year-old lady presented with a 1-week history of orthopnoea, paroxysmal nocturnal dyspnoea, night sweats and a productive cough. She had no recent history of travel. Transthoracic echocardiogram revealed preserved left ventricular systolic function with abnormal pericardial thickening and restrictive left ventricular filling consistent with pericardial constriction. Read More

    Strongyloides stercoralis in solid organ transplantation: early diagnosis gets the worm.
    Curr Opin Organ Transplant 2017 Aug;22(4):336-344
    aDepartment of Surgery, Division of Surgical Critical Care bSherrie & Alan Conover Center for Liver Disease & Transplantation, Houston Methodist Hospital, Houston, Texas, USA.
    Purpose Of Review: Strongyloidiasis is a parasitic infection affecting millions of people worldwide. Complications of infection are strongly associated with alcoholism, immunosuppression, and organ transplantation. Delayed diagnosis results in hyperinfection syndrome and disseminated strongyloidiasis leading to mortality rates approaching 80%. Read More

    Viability of Strongyloides venezuelensis eggs and larvae in vermiculite containing the fungus Duddingtonia flagrans.
    Parasitol Res 2017 Jul 15;116(7):2047-2051. Epub 2017 May 15.
    Department of Parasitology, University of Vila Velha-ES, Vila Velha, ES, Brazil.
    Strongyloidiasis is the most clinically important disease among the infections caused by geohelminths, seeing that this parasite can cause autoinfection. The use of nematophagous fungi like Duddingtonia flagrans, that have predation action on eggs and infecciososas forms of helminths, emerges as an alternative method for environmental control. For this reason, analyzing the viability of larvae and eggs of Strongyloides venezuelensis and the action of Duddingtonia flagrans AC001 in vermiculite, as well as the action of the nematophagous fungi in different growth stages, is important to elaborate and define the best culture conditions that favor the activity of the fungus. Read More

    Strongyloides seroprevalence before and after an ivermectin mass drug administration in a remote Australian Aboriginal community.
    PLoS Negl Trop Dis 2017 May 15;11(5):e0005607. Epub 2017 May 15.
    Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
    Background: Strongyloides seroprevalence is hyper-endemic in many Australian Aboriginal and Torres Strait Islander communities, ranging from 35-60%. We report the impact on Strongyloides seroprevalence after two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community.

    Methods: Utilizing a before and after study design, we measured Strongyloides seroprevalence through population census with sequential MDAs at baseline and month 12. Read More

    First molecular identification and genetic diversity of Strongyloides stercoralis and Strongyloides fuelleborni in human communities having contact with long-tailed macaques in Thailand.
    Parasitol Res 2017 Jul 12;116(7):1917-1923. Epub 2017 May 12.
    Research and Diagnostic Center for Emerging Infectious Diseases, Mekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand.
    The parasitic nematodes, Strongyloides stercoralis and Strongyloides fuelleborni, can infect humans and non-human primates. We amplified and sequenced a portion of the 18S ribosomal RNA gene (rRNA) and of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene of Strongyloides from humans in the study area in Thailand, where people have frequent contact with long-tailed macaques. Fresh stool samples were obtained from 213 people and were examined using the agar plate culture method. Read More

    Serological and molecular tests for the diagnosis of Strongyloides stercoralis infection in dogs.
    Parasitol Res 2017 Jul 10;116(7):2027-2029. Epub 2017 May 10.
    Centre for Tropical Diseases, Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024, Negrar, Verona, Italy.
    Strongyloides stercoralis can cause severe infection both in humans and dogs. Coproparasitological examination has low sensitivity for the diagnosis of this parasite; hence, different diagnostic techniques have been implemented. However, serology and molecular methods have been assessed almost exclusively in humans. Read More

    Twenty-five Years of Chronic Strongyloidiasis in an Immigrant.
    Clin Med Insights Case Rep 2017 8;10:1179547616684828. Epub 2017 Feb 8.
    Internal Medicine Residency, St. Elizabeth's Medical Center, Brighton, MA, USA.
    Chronic strongyloidiasis is an infection of the tropical regions, caused by the nematode Strongyloides stercoralis. In the United States, patients are typically immigrants. The very long asymptomatic phase followed by the clinical presentation of the disease mimics asthma, chronic obstructive pulmonary disease (COPD), or inflammatory bowel disease (IBD) as in this case report. Read More

    Pulmonary strongyloidiasis: assessment between manifestation and radiological findings in 16 severe strongyloidiasis cases.
    BMC Infect Dis 2017 May 2;17(1):320. Epub 2017 May 2.
    Department of Infectious Diseases, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
    Background: Strongyloidiasis is a chronic parasitic infection caused by Strongyloides stercoralis. Severe cases such as, hyperinfection syndrome (HS) and disseminated strongyloidiasis (DS), can involve pulmonary manifestations. These manifestations frequently aid the diagnosis of strongyloidiasis. Read More

    Modulation of Mycobacterium tuberculosis-specific humoral immune responses is associated with Strongyloides stercoralis co-infection.
    PLoS Negl Trop Dis 2017 May 1;11(5):e0005569. Epub 2017 May 1.
    National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.
    Background / Objectives: Helminth infections are known to influence T cell responses in latent tuberculosis (LTBI). Whether helminth infections also modulate B cell responses in helminth-tuberculosis co-infection is not known.

    Methods: We assessed Mycobacterium tuberculosis (Mtb)-antigen specific IgM and IgG levels, circulating levels of the B cell growth factors, BAFF and APRIL and the absolute numbers of the various B cell subsets in individuals with LTBI, LTBI with coincident Strongyloides stercoralis (Ss) infection (LTBI/Ss) and in those with Ss infection alone (Ss). Read More

    Identification of antigenic proteins in Strongyloides stercoralis by proteomic analysis.
    Parasitol Res 2017 Jun 29;116(6):1687-1693. Epub 2017 Apr 29.
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
    Strongyloides stercoralis is an intestinal helminth that infects people worldwide. Hyperinfection or disseminated human strongyloidiasis can involve vital organs, leading to lethal outcomes. We analyzed immunoproteomics of antigenic spots, derived from S. Read More

    A Strong and Fortuitous Case of Dyspnea.
    J La State Med Soc 2017 Mar-Apr;169(2):51. Epub 2017 Apr 15.
    Department of Internal Medicine, Tulane Health Sciences Center in New Orleans, LA.
    Case: A 48 year-old man with no past medical history was sent to our emergency department (ED); from a primary care clinic for hypertensive urgency of 200/130. The man reported an intermittent non-productive cough of approximately one year's duration and worsening dyspnea on exertion and orthopnea over the last month with lower extremity swelling. Of note, he emigrated from Honduras twenty years ago. Read More

    [Clinical and epidemiological characteristics of strongyloidiasis in patients with comorbidities].
    Rev Chilena Infectol 2017 Feb;34(1):47-53
    Centro de Pesquisas Aggeu Magalhães, Departamento de Parasitología, Serviço de Referência Nacional em Filarioses, Fundação Oswaldo Cruz, Pernambuco, Brasil.
    The strongyloidiasis is a parasitic disease that poses as a serious public health problem, mainly in tropical and subtropical countries. Over the years, some conditions, such as advances in corticosteroid treatment and immunosuppressive diseases, have improved not only the increase in cases of strongyloidiasis, but also the emergence of severe forms of the disease and / or deaths. For these reasons, the objective of this study is to make a critical analysis of the occurrence of strongyloidiasis in patients with comorbidities, describing clinical and epidemiological characteristics associated with these diseases that can highlight the importance of monitoring this parasitosis in most susceptible groups. Read More

    In vitro efficacy of latex and purified papain from Carica papaya against Strongyloides venezuelensis eggs and larvae.
    Rev Inst Med Trop Sao Paulo 2017 Apr 3;59:e7. Epub 2017 Apr 3.
    Universidade Federal de Goiás, Laboratório de Parasitologia, Jataí, Goiás, Brazil.
    Latex from Carica papaya is rich in bioactive compounds, especially papain, which may help to control parasitic diseases. This study evaluated the efficacy of latex from C. papaya and purified papain against Strongyloides venezuelensis. Read More

    A case of Strongyloides hyperinfection syndrome in the setting of persistent eosinophilia but negative serology.
    Diagn Microbiol Infect Dis 2017 Jun 14;88(2):168-170. Epub 2017 Mar 14.
    Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place 1090, New York, NY, 10029.
    Strongyloides stercoralis is a unique intestinal nematode with the ability to replicate and complete its life cycle without leaving the host. We report a fatal case of Strongyloides hyperinfection syndrome in a patient who had persistent eosinophilia for several years but negative Strongyloides serology. Our case suggests that ELISA serologies cannot solely be relied upon to diagnose Strongyloides stercoralis infection; history and clinical judgment remain crucial to this diagnosis. Read More

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