3,979 results match your criteria Strongyloidiasis


The Experimental Infections of the Human Isolate of Strongyloides Stercoralis in a Rodent Model (The Mongolian Gerbil, Meriones Unguiculatus).

Pathogens 2019 Feb 5;8(1). Epub 2019 Feb 5.

Lymphatic Filariasis and Tropical Medicine Research Unit, Chulalongkorn Medical Research Center, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Strongyloidiasis is life-threatening disease which is mainly caused by infection. Autoinfection of the parasite results in long-lasting infection and fatal conditions, hyperinfection and dissemination (primarily in immunosuppressed hosts). However, mechanisms of autoinfection and biology remain largely unknown. Read More

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http://dx.doi.org/10.3390/pathogens8010021DOI Listing
February 2019

The investigation of Strongyloides stercoralis seroprevalence in immunosupressed patients in Turkey

Turk J Med Sci 2019 Feb 11;49(1):16-19. Epub 2019 Feb 11.

Background/aim: In immunosuppressed patients, strongyloidiasis can be lifethreatening because of hyperinfection or dissemination. Therefore, diagnosis of S. stercoralis is important in immunosuppressed patients with chronic strongyloidiasis. Read More

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http://dx.doi.org/10.3906/sag-1804-16DOI Listing
February 2019

Hemoptysis in the Immunocompromised Patient: Do Not Forget Strongyloidiasis.

Trop Med Infect Dis 2019 Feb 12;4(1). Epub 2019 Feb 12.

Department of Medicine, Division of Infectious Diseases, University of Texas Health, San Antonio, TX 78229, USA.

Strongyloidiasis, due to infection with the nematode , affects millions of people in the tropics and subtropics. has a unique auto-infective lifecycle such that it can persist in the human host for decades. In immunosuppressed patients, especially those on corticosteroids, potentially fatal disseminated strongyloidiasis can occur, often with concurrent secondary infections. Read More

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http://dx.doi.org/10.3390/tropicalmed4010035DOI Listing
February 2019

Lethal strongyloidiasis - Diagnostic and forensic issues.

Authors:
Roger W Byard

J Forensic Leg Med 2019 Feb 2;62:103-106. Epub 2019 Feb 2.

School of Medicine, Level 2 Medical School North Building, The University of Adelaide, Frome Road, Forensic Science South Australia (FSSA), Adelaide, 5005, SA, Australia. Electronic address:

Strongyloidiasis is an infectious disease affecting approximately 30-100 million people globally. The main human pathogen is Strongyloides stercoralis which may cause a brief period of acute symptoms and signs after the initial infection, and then lapse into a chronic asymptomatic carrier state for decades due to the nematode's unique ability to autoinfect hosts. Immunosuppression from steroid therapy, T-lymphocytic viral (HTLV-1) infections, or a variety of underlying medical conditions may then result in dissemination and the highly lethal and infectious hyperinfection syndrome. Read More

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http://dx.doi.org/10.1016/j.jflm.2019.01.014DOI Listing
February 2019
1 Read

Migration Medicine.

Infect Dis Clin North Am 2019 Mar;33(1):265-287

University Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili, Piazza del Mercato, 15, Lombardy, Brescia 25121, Italy; UNESCO Chair "Training and Empowering Human Resources for Health Development in Resource-Limited Countries", University of Brescia, Brescia, Italy.

Migration is increasing and practitioners need to be aware of the unique health needs of this population. The prevalence of infectious diseases among migrants varies and generally mirrors that of their countries of origin, but is modified by the circumstance of migration, the presence of pre-arrival screening programs and post arrival access to health care. To optimize the health of migrants practitioners; (1) should take all opportunities to screen migrants at risk for latent infections such as tuberculosis, chronic hepatitis B and C, HIV, strongyloidiasis, schistosomiasis and Chagas disease, (2) update routine vaccines in all age groups and, (3) be aware of "rare and tropical infections" related to migration and return travel. Read More

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http://dx.doi.org/10.1016/j.idc.2018.10.014DOI Listing
March 2019
1 Read

Strongyloidiasis: A Neglected Tropical Disease.

Infect Dis Clin North Am 2019 Mar;33(1):135-151

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 - Room B1-03, 4 Center Drive, Bethesda, MD 20892-0425, USA. Electronic address:

Most of the 30 to 100 million people infected with Strongyloides stercoralis have subclinical (or asymptomatic) infections. These infections are commonly chronic and longstanding. A change in immune status can increase parasite numbers, leading to hyperinfection syndrome, dissemination, and death if unrecognized. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08915520183009
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http://dx.doi.org/10.1016/j.idc.2018.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367705PMC
March 2019
4 Reads

Prevalence of strongyloidiasis and schistosomiasis among migrants: a systematic review and meta-analysis.

Lancet Glob Health 2019 Feb;7(2):e236-e248

Centre for Clinical Epidemiology of the Lady Davis Institute for Medical Research, McGill University, Montreal, QC, Canada; Division of Infectious Diseases and Clinical Epidemiology, SMBD Jewish General Hospital, McGill University, Montreal, QC, Canada. Electronic address:

Background: Global migration from regions where strongyloidiasis and schistosomiasis are endemic to non-endemic countries has increased the potential individual and public health effect of these parasitic diseases. We aimed to estimate the prevalence of these infections among migrants to establish which groups are at highest risk and who could benefit from screening.

Methods: We did a systematic review and meta-analysis of strongyloidiasis and schistosomiasis prevalence among migrants born in endemic countries. Read More

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http://dx.doi.org/10.1016/S2214-109X(18)30490-XDOI Listing
February 2019
2 Reads

Strongyloidiasis and schistosomiasis: lessons from migrants' data.

Lancet Glob Health 2019 Feb;7(2):e171-e172

Department of Medical Parasitology, School of Medicine, Catholic University of Health and Allied Sciences, PO Box 1464, Mwanza, Tanzania. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(18)30522-9DOI Listing
February 2019
1 Read

Disseminated Strongyloidiasis.

Acta Dermatovenerol Croat 2018 Dec;26(4):333-336

Professor Marcia Ramos-e-Silva, MD, PhD, Rua Dona Mariana 143 / C-32, Rio de Janeiro 22280-020, Brazil;

Strongyloidiasis is a parasitic infestation caused by the helminth Strongyloides stercoralis. It is essentially gastrointestinal and in general asymptomatic but can sometimes present with skin signs. Immunocompromised patients can develop the disseminated form of the disease due to the parasite's opportunistic behavior, as in cases of coinfection by the human T-lymphotropic type 1 virus (HTLV-1). Read More

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December 2018
4 Reads

Epidemiology of Strongyloides stercoralis infection in Bolivian patients at high risk of complications.

PLoS Negl Trop Dis 2019 01 17;13(1):e0007028. Epub 2019 Jan 17.

Division of Tropical and Humanitarian Medicine, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

Background: Strongyloidiasis can be fatal in immunocompromised patients, but few epidemiological studies investigated the burden of this neglected tropical disease among these populations, particularly in low- and middle-income countries such as Bolivia. This study aimed to fill in this gap by estimating prevalence rate and risk factors associated with strongyloidiasis among patients at high risk of complications.

Methods: A cross-sectional study was carried out in Santa Cruz (elevation 400 meters, tropical climate) and Cochabamba (elevation 2,500 meters, temperate climate), among patients with cancer, HIV infection and rheumatic or hematologic disease, using four coproparasitological techniques and one serological (ELISA) test. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007028
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http://dx.doi.org/10.1371/journal.pntd.0007028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353209PMC
January 2019
6 Reads

Central nervous system Strongyloides stercoralis. A case report.

Turk Neurosurg 2018 Sep 28. Epub 2018 Sep 28.

Medifema Hospital.

Strongyloidiasis is an infestation caused by the intestinal nematode Strongyloides stercoralis. It is potentially fatal in immuno-compromised hosts due to its capacity to cause an overwhelming hyperinfestation however infested healthy individuals are usually asymptomatic. Hyperinfestation is extremely rare in the Central Nervous System (CNS) and usually limited to the gastrointestinal tract or lungs. Read More

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http://dx.doi.org/10.5137/1019-5149.JTN.22886-18.2DOI Listing
September 2018
3 Reads

Diagnostic update for an unusual case: recurrent strongyloidiasis.

J R Army Med Corps 2019 Jan 13. Epub 2019 Jan 13.

Army Medical Services Support Unit, Camberley, UK.

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http://dx.doi.org/10.1136/jramc-2018-001143DOI Listing
January 2019

Secretome analysis of Strongyloides venezuelensis parasitic stages reveals that soluble and insoluble proteins are involved in its parasitism.

Parasit Vectors 2019 Jan 9;12(1):21. Epub 2019 Jan 9.

Division of Parasitology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.

Background: Parasites excrete and secrete a wide range of molecules that act as the primary interface with their hosts and play critical roles in establishing parasitism during different stages of infection. Strongyloides venezuelensis is a gastrointestinal parasite of rats that is widely used as a laboratory model and is known to produce both soluble and insoluble (adhesive) secretions during its parasitic stages. However, little is known about the constituents of these secretions. Read More

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http://dx.doi.org/10.1186/s13071-018-3266-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327390PMC
January 2019
1 Read

Prevalence and associated risk factors of infection in Lower Myanmar.

Trop Med Health 2018 18;46:43. Epub 2018 Dec 18.

2Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692 Japan.

Background: Strongyloidiasis is prevalent in Southeast Asian regions along with other soil-transmitted helminthiases, but only limited present-day data was available for Myanmar.

Methods: A prevalence survey for infection was conducted among villagers in rural areas of three townships located in the Lower Myanmar during 2014-2016 by agar plate culture method in combination with specific identification by molecular assays. Risk factors associated with infection were assessed by analyzing questionnaires obtained from study participants. Read More

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http://dx.doi.org/10.1186/s41182-018-0126-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299610PMC
December 2018
1 Read

Donor-derived strongyloidiasis in a Saudi pediatric kidney transplant recipient: A case report and mini-review.

Pediatr Transplant 2018 Dec 21:e13315. Epub 2018 Dec 21.

Division of Pediatric Infectious Diseases, King Abdullah Specialized Children's Hospital (KASCH), National Guard Health Affairs, Riyadh, Saudi Arabia.

S. stercoralis infection has been identified as a donor-derived infection in cases of solid organ transplant among recipients with no prior risk factor for parasitic exposure. Worldwide and regional reports from the adult kidney transplant population highlight this indirect method of infection and caution about delayed diagnosis, severe complications, and death related to donor-derived S. Read More

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http://doi.wiley.com/10.1111/petr.13315
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http://dx.doi.org/10.1111/petr.13315DOI Listing
December 2018
9 Reads

Effectiveness of Screening and Treatment Approaches for Schistosomiasis and Strongyloidiasis in Newly-Arrived Migrants from Endemic Countries in the EU/EEA: A Systematic Review.

Int J Environ Res Public Health 2018 Dec 20;16(1). Epub 2018 Dec 20.

ISGlobal, Barcelona Institute for Global Health (ISGlobal-CRESIB, Hospital Clínic-University of Barcelona), E-08036 Barcelona, Spain.

We aimed to evaluate the evidence on screening and treatment for two parasitic infections-schistosomiasis and strongyloidiasis-among migrants from endemic countries arriving in the European Union and European Economic Area (EU/EEA). We conducted a systematic search of multiple databases to identify systematic reviews and meta-analyses published between 1 January 1993 and 30 May 2016 presenting evidence on diagnostic and treatment efficacy and cost-effectiveness. We conducted additional systematic search for individual studies published between 2010 and 2017. Read More

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http://dx.doi.org/10.3390/ijerph16010011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339107PMC
December 2018
2 Reads

IgG reactivity with 40-35 kDa soluble and membrane antigen of Strongyloides venezuelensis in immunocompromised patients.

Acta Trop 2019 Feb 12;190:357-360. Epub 2018 Dec 12.

Laboratório de Investigação Médica (LIM/06 - Laboratório de Imunopatologia da Esquistossomose), Hospital das Clínicas da Faculdade de Medicina, USP, São Paulo, Brazil; Instituto de Medicina Tropical de São Paulo, USP, São Paulo, Brazil.

Immunocompromised patients constitute a risk group for the development of severe clinical forms of human strongyloidiasis. The diagnosis of this infection is primarily performed by parasitological techniques, but with low sensitivity. Serological techniques appear as an alternative, especially with heterologous antigens use. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0001706X183034
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http://dx.doi.org/10.1016/j.actatropica.2018.12.020DOI Listing
February 2019
8 Reads

Coinfections between Persistent Parasitic Neglected Tropical Diseases and Viral Infections among Prisoners from Sub-Saharan Africa and Latin America.

J Trop Med 2018 6;2018:7218534. Epub 2018 Nov 6.

Division of Prison Health, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

In Swiss prisons, more than 70% of detained people are foreigners and over one-third originate from sub-Saharan Africa or Latin America. These two regions are endemic for various tropical diseases and viral infections, which persist after migration to nonendemic countries. Parasitic infections (schistosomiasis; strongyloidiasis) and cooccurrent viral infections (HIV, hepatitis B (HBV), and hepatitis C (HCV)) are especially of concern for clinical care but have been neglected in empirical research. Read More

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https://www.hindawi.com/journals/jtm/2018/7218534/
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http://dx.doi.org/10.1155/2018/7218534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247427PMC
November 2018
2 Reads

Strongyloides venezuelensis infection augments arterial blood pressure in male wistar rats.

Acta Trop 2019 Feb 6;190:350-355. Epub 2018 Dec 6.

ICBS- Instituto de Ciências Biológicas e da Saúde, UFMT- Universidade Federal de Mato Grosso, Barra do Garças, Mato Grosso, Brazil. Electronic address:

Strongyloidiasis is an intestinal parasitosis that occurs in humans infected by Strongyloides stercoralis mostly. At its acute phase, symptoms like constipation, diarrhea and abdominal pain can be observed, but become asymptomatic for a long time, until an immunosuppression will start a hyperinfection and the dissemination of the disease, prevalent on the elderly population in tropical countries. Ivermectina treatment is the currently choice for this disease, due to its great efficacy and the results reported. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.12.007DOI Listing
February 2019
1 Read

Seroepidemiological aspects of human infection by Strongyloides stercoralis in Alfenas, southern Minas Gerais, Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):855-859

Laboratório de Diagnóstico de Parasitoses, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.

Introduction: In most Strongyloides stercoralis infected individuals, nematoidosis occurs asymptomatically, but in immunocompromised patients, it can cause hyperinfection. Serological techniques seem to be a good alternative for detecting this parasite.

Methods: The frequency of seropositivity for strongyloidiasis in Alfenas, MG, was estimated using the enzyme linked immunosorbent assay on blood samples, between May and August of 2015. Read More

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http://dx.doi.org/10.1590/0037-8682-0090-2018DOI Listing
February 2019
2 Reads

Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome.

Case Rep Infect Dis 2018 28;2018:6870768. Epub 2018 Oct 28.

Department of Medicine, Poona Hospital and Research Center, Pune, Maharashtra, India.

Parasitic infections such as and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease. Read More

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https://www.hindawi.com/journals/criid/2018/6870768/
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http://dx.doi.org/10.1155/2018/6870768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230409PMC
October 2018
6 Reads

Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti.

PLoS Negl Trop Dis 2018 11 29;12(11):e0006992. Epub 2018 Nov 29.

Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

Infections with helminth parasites are controlled by a concerted action of innate and adaptive effector cells in the frame of a type 2 immune response. Basophils are innate effector cells that may also contribute to the initiation and amplification of adaptive immune responses. Here, we use constitutively basophil-deficient Mcpt8-Cre mice to analyze the impact of basophils during initiation and execution of the protective type 2 responses to both, a primary infection and a challenge infection of immune mice with the helminth parasite Strongyloides ratti. Read More

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http://dx.plos.org/10.1371/journal.pntd.0006992
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http://dx.doi.org/10.1371/journal.pntd.0006992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289456PMC
November 2018
7 Reads

High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study.

PLoS Negl Trop Dis 2018 11 29;12(11):e0007010. Epub 2018 Nov 29.

ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.

Background: Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, using our institution's serum bank. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289465PMC
November 2018
2 Reads

Gastroduodenal involvement in disseminated strongyloidiasis.

JGH Open 2018 Apr 22;2(2):75-76. Epub 2018 Feb 22.

Department of Gastroenterology Kobe City Medical Center General Hospital Kobe Japan.

Here, we report the case of a 57-year-old Peruvian man on long-term corticosteroid therapy for a drug allergy and proton pump inhibitors for chronic dyspepsia symptoms. Upper gastrointestinal endoscopy showed multiple white granular lesions and widespread erosions in the stomach. Our findings indicate that gastric strongyloidiasis should be carefully considered in high-risk patients even if endoscopic findings are nonspecific. Read More

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http://dx.doi.org/10.1002/jgh3.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206995PMC
April 2018
1 Read

Serodiagnosis and early detection of Strongyloides stercoralis infection.

J Microbiol Immunol Infect 2018 Oct 11. Epub 2018 Oct 11.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia. Electronic address:

Strongyloidiasis is a major neglected tropical disease with the potential of causing lifelong infection and mortality. One of the ways for effective control of this disease is developing improved diagnostics, particularly using serological approaches. A serological test can achieve high diagnostic sensitivity and specificity, has the potential for point-of-care translation, and can be used as a screening tool for early detection. Read More

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http://dx.doi.org/10.1016/j.jmii.2018.10.001DOI Listing
October 2018
1 Read

Efficacy of ivermectin to control Strongyloides stercoralis infection in sheltered dogs.

Acta Trop 2019 Feb 19;190:204-209. Epub 2018 Nov 19.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy; Dipartimento di Diagnostica e Sanità pubblica, Università degli Studi di Verona, Italy.

In dogs, information on treatments against S. stercoralis infection is rare and anecdotal. The aim of the present work was to evaluate the treatment outcome of S. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.11.014DOI Listing
February 2019
14 Reads

Strongyloidiasis and Culture-Negative Suppurative Meningitis, Japan, 1993-2015.

Emerg Infect Dis 2018 Dec;24(12):2378-2380

Community-acquired Enterobacteriaceae infection and culture-negative meningitis are rare and atypical subtypes of meningitis in adults. Of 37 patients who had atypical suppurative meningitis during 1993-2015 in Okinawa, Japan, 54.5% had strongyloidiasis, of which 9. Read More

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http://dx.doi.org/10.3201/eid2412.180375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256405PMC
December 2018
1 Read

Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem.

Am J Trop Med Hyg 2019 Jan;100(1):130-134

Division of Infectious Diseases, Department of Medicine, St. Joseph's Health Centre, Toronto, Canada.

Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the CNS sample in one case. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0813
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http://dx.doi.org/10.4269/ajtmh.18-0813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335887PMC
January 2019
22 Reads

Fatal strongyloidiasis after corticosteroid therapy for presumed chronic obstructive pulmonary disease.

JMM Case Rep 2018 Sep 11;5(9):e005165. Epub 2018 Sep 11.

Sumeru Hospital, Dhapakhel, Lalitpur, Nepal.

Introduction: Strongyloidiasis is a neglected tropical disease with global prevalence. Under some cases of immune suppression (especially with corticosteroid administration), the nematode involved disseminates, leading to an amplified, possibly lethal hyper-infection syndrome.

Case Presentation: A 56-year-old Nepalese man presenting with chief complaints of nausea, vomiting, joint pain and abdominal cramps was admitted to Sumeru Hospital. Read More

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http://www.microbiologyresearch.org/content/journal/jmmcr/10
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http://dx.doi.org/10.1099/jmmcr.0.005165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230759PMC
September 2018
8 Reads

Accuracy of Urine and Serum Assays for the Diagnosis of Strongyloidiasis by Three Enzyme-Linked Immunosorbent Assay Protocols.

Am J Trop Med Hyg 2019 Jan;100(1):127-129

Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand.

To evaluate the accuracy and reliability of urine assay for the diagnosis of strongyloidiasis, three different immunoassays were used to assess the diagnostic accuracy of anti- immunoglobulin G (IgG) in urine and compared with those in serum samples. Analyses by InBios enzyme-linked immunosorbent assay (ELISA) kit (recombinant NIE antigen), SciMedx ELISA kit ( antigen), and our in-house ELISA ( antigen) yielded comparable diagnostic performances between urine and serum assays. Levels of -specific IgG in urine significantly correlated with those in serum. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0569
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http://dx.doi.org/10.4269/ajtmh.18-0569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335925PMC
January 2019
9 Reads

Hypermetabolic Diffuse Proximal Small Bowel Wall Thickening on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography? Consider Strongyloidiasis among the Differentials.

Indian J Nucl Med 2018 Oct-Dec;33(4):368-369

Department of Nuclear Medicine, MIOT International, Chennai, Tamil Nadu, India.

Strongyloidiasis is an emerging tropical/subtropical parasitic infection commonly encountered in immunocompromised patients and often accompanied by life-threatening gram-negative bacteremia. We presented an interesting image of a critically ill 66-year-old lady, an asthmatic on high dose steroids, presenting with unexplained fever and vomiting where fluorodeoxyglucose positron emission tomography/computed tomography and endoscopic biopsy revealed this often neglected pathogenic nematode. Read More

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http://www.ijnm.in/text.asp?2018/33/4/368/242953
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http://dx.doi.org/10.4103/ijnm.IJNM_96_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194780PMC
November 2018
2 Reads

Severe strongyloidiasis and systemic vasculitis: comorbidity, association or both? Case-based review.

Rheumatol Int 2018 Dec 23;38(12):2315-2321. Epub 2018 Oct 23.

Clinic of Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia.

A possible association between strongyloidiasis and systemic vasculitis is rarely reported in the literature. We report the case of a patient with severe strongyloidiasis and an angiographic finding consistent with polyarteritis nodosa. Diagnosis of strongyloidiasis was made by finding of larvae and adult parasites in samples of the upper gastrointestinal tract mucosa and stool. Read More

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http://link.springer.com/10.1007/s00296-018-4178-y
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http://dx.doi.org/10.1007/s00296-018-4178-yDOI Listing
December 2018
13 Reads

[Severe infection: a case report].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Sep;30(4):479-480

Department of Laboratory Medicine, Fujian Provincial Hospital, Fuzhou 350001, China.

This paper reports a severe case of infection during routine sputum smear examinations, due to cough and shortness of breath, so as to improve clinicians' awareness of strongyloidiasis to avoid and reduce misdiagnosis and missed diagnosis. Read More

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http://dx.doi.org/10.16250/j.32.1374.2018214DOI Listing
September 2018
3 Reads

Parasitic Infections Associated with Unfavourable Outcomes in Transplant Recipients.

Medicina (Kaunas) 2018 May 1;54(2). Epub 2018 May 1.

Department of Nephrology, Transplantology and Internal Diseases, Medical University of Gdansk, 80⁻210 Gdansk, Poland.

. The immunosuppression used after transplantation (Tx) is associated with an increased risk of opportunistic infections. In Europe, parasitic infections after Tx are much less common than viral, bacterial and fungal ones. Read More

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http://www.mdpi.com/1648-9144/54/2/27
Publisher Site
http://dx.doi.org/10.3390/medicina54020027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037257PMC
May 2018
13 Reads

Impact of the health education and preventive equipment package (HEPEP) on prevention of Strongyloides stercoralis infection among rural communities in Northeast Thailand: a cluster randomized controlled trial.

BMC Public Health 2018 Oct 19;18(1):1184. Epub 2018 Oct 19.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Strongyloidiasis is prevalent in northeast Thailand. This study aimed to evaluate the impact of the Health Education and Preventive Equipment Package (HEPEP), a package we developed to improve awareness and aid in the prevention of Strongyloides stercoralis infection among rural communities in northeast Thailand.

Methods: This was an intervention trial conducted in 12 villages (six interventions and six controls) in rural areas of northeast Thailand from March 2016 to September 2017. Read More

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http://dx.doi.org/10.1186/s12889-018-6081-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194667PMC
October 2018
3 Reads

Case Report: Subcutaneous Ivermectin Pharmacokinetics in Disseminated Infection: Plasma and Postmortem Analysis.

Am J Trop Med Hyg 2018 Sep 17. Epub 2018 Sep 17.

Pathology Queensland, Brisbane, Australia.

Parenteral ivermectin treatment of disseminated strongyloidiasis and hyperinfection is increasing, although not licensed in humans and with limited pharmacokinetic data available. Plasma and postmortem tissue analysis in an HIV/hepatitis C virus-positive man with disseminated strongyloidiasis suggests loading subcutaneous ivermectin doses are required, from which the central nervous system is protected. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283511PMC
September 2018
2 Reads

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.

Wien Klin Wochenschr 2018 Oct 15;130(19-20):581-588. Epub 2018 Oct 15.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.

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http://dx.doi.org/10.1007/s00508-018-1395-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209003PMC
October 2018
4 Reads

Donor-derived strongyloidiasis after organ transplantation in Norway.

Transpl Infect Dis 2019 Feb 28;21(1):e13008. Epub 2018 Oct 28.

Regional Advisory Unit for Imported and Tropical Diseases, Department of Infectious Diseases, Oslo University Hospital - Ullevål, Oslo, Norway.

Strongyloides stercoralis is an intestinal helminth which in humans can cause asymptomatic chronic infection maintained for decades through its auto-infective cycle. During solid organ transplantation, recipients may unintentionally receive an organ infected with strongyloides. This is a very rare complication but may have deadly outcome if not detected. Read More

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http://dx.doi.org/10.1111/tid.13008DOI Listing
February 2019
3 Reads

Case Report: Hyperinfection in a Patient with HTLV-1: A Case Report of an Infection with Filariform and Rhabditiform Larvae, Eggs, and Free-Living Adult Females.

Am J Trop Med Hyg 2018 Oct 1. Epub 2018 Oct 1.

Faculdade de Farmácia, Universidade Federal da Bahia (UFBA), Salvador, Brazil.

is the main etiological agent of human strongyloidiasis. Severe strongyloidiasis is commonly associated to alcoholism, corticostereoid use, and human T cell lymphotropic virus type 1 (HTLV-1) coinfection. Herein, we report a case of a 13-year-old boy coinfected with and HTLV-1, excreting several parasitic forms in the stool. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0402
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http://dx.doi.org/10.4269/ajtmh.18-0402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283480PMC
October 2018
10 Reads

Paediatric Strongyloidiasis in Central Australia.

Trop Med Infect Dis 2018 Jun 13;3(2). Epub 2018 Jun 13.

FRACP, Head of Department, Department of Paediatrics, Alice Springs Hospital, P.O. Box 2234, Alice Springs NT 0871, Australia.

Few published studies are available describing the prevalence of paediatric strongyloidiasis in endemic areas within Australia. This literature review and exploratory clinical audit presents the first seroprevalence data for paediatric patients in Central Australia. A total of 16. Read More

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http://dx.doi.org/10.3390/tropicalmed3020064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073483PMC
June 2018
13 Reads

Argument for Inclusion of Strongyloidiasis in the Australian National Notifiable Disease List.

Trop Med Infect Dis 2018 Jun 5;3(2). Epub 2018 Jun 5.

College of Science and Engineering, Flinders University, Bedford Park, SA 5042, Australia.

Strongyloidiasis is an infection caused by the helminth, . Up to 370 million people are infected with the parasite globally, and it has remained endemic in the Indigenous Australian population for many decades. Strongyloidiasis has been also reported in other Australian populations. Read More

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http://www.mdpi.com/2414-6366/3/2/61
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http://dx.doi.org/10.3390/tropicalmed3020061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073110PMC
June 2018
3 Reads

The Unique Life Cycle of Strongyloides stercoralis and Implications for Public Health Action.

Trop Med Infect Dis 2018 May 25;3(2). Epub 2018 May 25.

School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, QLD 4700, Australia.

has one of the most complex life cycles of the human-infecting nematodes. A common misconception in medical and public health professions is that in its biology is akin to other intestinal nematodes, such as the hookworms. Despite original evidence provided by medical and veterinary research about this unique helminth, many assumptions have entered the scientific literature. Read More

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http://www.mdpi.com/2414-6366/3/2/53
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http://dx.doi.org/10.3390/tropicalmed3020053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073624PMC
May 2018
4 Reads

The Health Effects of Strongyloidiasis on Pregnant Women and Children: A Systematic Literature Review.

Trop Med Infect Dis 2018 May 18;3(2). Epub 2018 May 18.

College of Medicine and Dentistry, James Cook University, Smithfield QLD 4878, Australia.

Strongyloidiasis is a helminth infection that remains under-researched despite its ability to cause significant illness. Women and children may be at particular risk of health consequences from this parasite. This systematic literature review aims to examine research on the long-term health effects that strongyloidiasis has in pregnant women and children. Read More

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http://dx.doi.org/10.3390/tropicalmed3020050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073583PMC
May 2018
14 Reads

A Community-Directed Integrated Control Program in Queensland, Australia.

Trop Med Infect Dis 2018 May 4;3(2). Epub 2018 May 4.

College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.

This paper describes two phases of a community-directed intervention to address strongyloidiasis in the remote Aboriginal community of Woorabinda in central Queensland, Australia. The first phase provides the narrative of a community-driven 'treat-and-test' mass drug administration (MDA) intervention that was co-designed by the Community Health Service and the community. The second phase is a description of the re-engagement of the community in order to disseminate the key factors for success in the previous MDA for , as this information was not shared or captured in the first phase. Read More

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http://dx.doi.org/10.3390/tropicalmed3020048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073318PMC
May 2018
2 Reads

Cross-Cultural, Aboriginal Language, Discovery Education for Health Literacy and Informed Consent in a Remote Aboriginal Community in the Northern Territory, Australia.

Trop Med Infect Dis 2018 Jan 29;3(1). Epub 2018 Jan 29.

School of Health, Medical and Applied Sciences, Central Queensland University, Bundaberg, QLD 4670, Australia.

Background: Education for health literacy of Australian Aboriginal people living remotely is challenging as their languages and worldviews are quite different from English language and Western worldviews. Becoming health literate depends on receiving comprehensible information in a culturally acceptable manner.

Methods: The study objective was to facilitate oral health literacy through community education about scabies and strongyloidiasis, including their transmission and control, preceding an ivermectin mass drug administration (MDA) for these diseases. Read More

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http://dx.doi.org/10.3390/tropicalmed3010015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136616PMC
January 2018
5 Reads

Application of PCR-Based Tools to Explore Strongyloides Infection in People in Parts of Northern Australia.

Trop Med Infect Dis 2017 Dec 8;2(4). Epub 2017 Dec 8.

School of Health, Medical and Applied Sciences, Central Queensland University, North Rockhampton, QLD 4700, Australia.

Strongyloidiasis, which is caused by infection with the nematode , is endemic to areas of northern Australia. Diagnosis in this region remains difficult due to the distances between endemic communities and diagnostic laboratories, leading to lengthy delays in stool processing for microscopy and culture. PCR represents a viable solution to this difficulty, having potential for high sensitivity detection of , even in older, unpreserved faecal samples. Read More

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http://dx.doi.org/10.3390/tropicalmed2040062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082066PMC
December 2017
4 Reads

Soil-Transmitted Helminths in Children in a Remote Aboriginal Community in the Northern Territory: Hookworm is Rare but Strongyloides stercoralis and Trichuris trichiura Persist.

Trop Med Infect Dis 2017 Oct 4;2(4). Epub 2017 Oct 4.

Menzies School of Health Research, Charles Darwin University, Darwin NT 0811, Australia.

(1) Background: soil-transmitted helminths are a problem worldwide, largely affecting disadvantaged populations. The little data available indicates high rates of infection in some remote Aboriginal communities in Australia. Studies of helminths were carried out in the same remote community in the Northern Territory in 1994⁻1996 and 2010⁻2011; (2) Methods: fecal samples were collected from children aged <10 years and examined for helminths by direct smear microscopy. Read More

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http://dx.doi.org/10.3390/tropicalmed2040051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082063PMC
October 2017
2 Reads

A case of chronic strongyloidiasis diagnosed by histopathological study.

Int J Infect Dis 2018 12 24;77:1-2. Epub 2018 Sep 24.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024 Negrar, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S12019712183451
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http://dx.doi.org/10.1016/j.ijid.2018.09.007DOI Listing
December 2018
16 Reads

Pulmonary strongyloidiasis presenting micronodules on chest computed tomography.

J Thorac Dis 2018 Aug;10(8):E612-E615

Department of Parasitology and Tropical Medicine, and Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.

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http://dx.doi.org/10.21037/jtd.2018.07.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129929PMC
August 2018
1 Read