2,451 results match your criteria Strongyloides Stercoralis


Implementation of a Strongyloides Screening Strategy in Solid Organ Transplant Donors and Recipients.

Clin Transplant 2019 Feb 17:e13497. Epub 2019 Feb 17.

Department of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL, USA.

Background: Strongyloides stercoralis infects 100 million people worldwide. Mortality rates in hyperinfection syndrome exceed 50%. Donor-derived Strongyloides infection has occurred after heart, kidney, kidney-pancreas and liver transplantation; yet, only 10% of the U. Read More

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http://dx.doi.org/10.1111/ctr.13497DOI Listing
February 2019

Comparison of ELISA and PCR of the 18S rRNA gene for detection of human strongyloidiasis using serum sample.

Infect Dis (Lond) 2019 Feb 18:1-8. Epub 2019 Feb 18.

c Cellular and Molecular Biology Research Center, Health Research Institute , Babol University of Medical Sciences , Babol , Iran.

Background: Strongyloides stercoralis infection is a neglected tropical disease with global distribution which is fatal in immunosuppressed patients. This study aimed to determine the prevalence of strongyloidiasis in immunocompromised individuals and cases with infectious diseases, as well as comparing ELISA and conventional PCR with coprological examination, in the central parts of Mazandaran province, northern Iran.

Methods: A single serum and a fresh stool samples were obtained from 272 and 220 patients, respectively. Read More

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http://dx.doi.org/10.1080/23744235.2019.1575978DOI Listing
February 2019

The Experimental Infections of the Human Isolate of Strongyloides Stercoralis in a Rodent Model (The Mongolian Gerbil, Meriones Unguiculatus).

Pathogens 2019 Feb 5;8(1). Epub 2019 Feb 5.

Lymphatic Filariasis and Tropical Medicine Research Unit, Chulalongkorn Medical Research Center, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Strongyloidiasis is life-threatening disease which is mainly caused by infection. Autoinfection of the parasite results in long-lasting infection and fatal conditions, hyperinfection and dissemination (primarily in immunosuppressed hosts). However, mechanisms of autoinfection and biology remain largely unknown. Read More

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http://dx.doi.org/10.3390/pathogens8010021DOI Listing
February 2019

The investigation of Strongyloides stercoralis seroprevalence in immunosupressed patients in Turkey

Turk J Med Sci 2019 Feb 11;49(1):16-19. Epub 2019 Feb 11.

Background/aim: In immunosuppressed patients, strongyloidiasis can be lifethreatening because of hyperinfection or dissemination. Therefore, diagnosis of S. stercoralis is important in immunosuppressed patients with chronic strongyloidiasis. Read More

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http://dx.doi.org/10.3906/sag-1804-16DOI Listing
February 2019
1 Read

Hemoptysis in the Immunocompromised Patient: Do Not Forget Strongyloidiasis.

Trop Med Infect Dis 2019 Feb 12;4(1). Epub 2019 Feb 12.

Department of Medicine, Division of Infectious Diseases, University of Texas Health, San Antonio, TX 78229, USA.

Strongyloidiasis, due to infection with the nematode , affects millions of people in the tropics and subtropics. has a unique auto-infective lifecycle such that it can persist in the human host for decades. In immunosuppressed patients, especially those on corticosteroids, potentially fatal disseminated strongyloidiasis can occur, often with concurrent secondary infections. Read More

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http://dx.doi.org/10.3390/tropicalmed4010035DOI Listing
February 2019
1 Read

Lethal strongyloidiasis - Diagnostic and forensic issues.

Authors:
Roger W Byard

J Forensic Leg Med 2019 Feb 2;62:103-106. Epub 2019 Feb 2.

School of Medicine, Level 2 Medical School North Building, The University of Adelaide, Frome Road, Forensic Science South Australia (FSSA), Adelaide, 5005, SA, Australia. Electronic address:

Strongyloidiasis is an infectious disease affecting approximately 30-100 million people globally. The main human pathogen is Strongyloides stercoralis which may cause a brief period of acute symptoms and signs after the initial infection, and then lapse into a chronic asymptomatic carrier state for decades due to the nematode's unique ability to autoinfect hosts. Immunosuppression from steroid therapy, T-lymphocytic viral (HTLV-1) infections, or a variety of underlying medical conditions may then result in dissemination and the highly lethal and infectious hyperinfection syndrome. Read More

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http://dx.doi.org/10.1016/j.jflm.2019.01.014DOI Listing
February 2019
1 Read

Comparison of loop-mediated isothermal amplification (LAMP) and real-time polymerase chain reaction (PCR) assays for the detection of in different specimen matrices.

J Clin Microbiol 2019 Feb 6. Epub 2019 Feb 6.

Parasitology Laboratory, Centre for Infectious Diseases and Microbiology, Institute for Clinical Pathology and Medical Research - New South Wales Health Pathology, Westmead Hospital, Westmead, New South Wales, Australia.

can cause disease that ranges from asymptomatic chronic infection to fatal hyperinfection. Diagnosis from stool can be challenging because the most sensitive conventional tests require live larvae to be effective and there can be low larval output in chronic infection. Nucleic acid amplification tests (NAAT) have been developed to complement existing diagnostic methods. Read More

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http://dx.doi.org/10.1128/JCM.01173-18DOI Listing
February 2019
1 Read

Strongyloidiasis: A Neglected Tropical Disease.

Infect Dis Clin North Am 2019 Mar;33(1):135-151

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 - Room B1-03, 4 Center Drive, Bethesda, MD 20892-0425, USA. Electronic address:

Most of the 30 to 100 million people infected with Strongyloides stercoralis have subclinical (or asymptomatic) infections. These infections are commonly chronic and longstanding. A change in immune status can increase parasite numbers, leading to hyperinfection syndrome, dissemination, and death if unrecognized. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08915520183009
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http://dx.doi.org/10.1016/j.idc.2018.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367705PMC
March 2019
4 Reads

Cardiac arrest in a case of systemic lupus erythematosus and hepatitis-B coinfection: Can be the culprit?

Trop Parasitol 2018 Jul-Dec;8(2):106-109. Epub 2018 Dec 27.

Department of General Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

is one of the most important helminths causing neglected tropical diseases. Its ability to cause autoinfection can lead to chronic infections and hyper infection, especially in autoimmune cases and prove to be highly fatal. We report a case of systemic lupus erythematosus (SLE) having hepatitis-B coinfection, who presented with rash all over the body, recurrent nausea, vomiting, cough, loose stool, and joint pain for 1 month and was later on found to be infected with . Read More

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http://www.tropicalparasitology.org/text.asp?2018/8/2/106/24
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http://dx.doi.org/10.4103/tp.TP_42_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329272PMC
December 2018
2 Reads

Liposome-based transfection enhances RNAi and CRISPR-mediated mutagenesis in non-model nematode systems.

Sci Rep 2019 Jan 24;9(1):483. Epub 2019 Jan 24.

School of Life Sciences, University of Warwick, Coventry, CV4 7AL, UK.

Nematodes belong to one of the most diverse animal phyla. However, functional genomic studies in nematodes, other than in a few species, have often been limited in their reliability and success. Here we report that by combining liposome-based technology with microinjection, we were able to establish a wide range of genomic techniques in the newly described nematode genus Auanema. Read More

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http://dx.doi.org/10.1038/s41598-018-37036-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345965PMC
January 2019

Disseminated Strongyloidiasis.

Acta Dermatovenerol Croat 2018 Dec;26(4):333-336

Professor Marcia Ramos-e-Silva, MD, PhD, Rua Dona Mariana 143 / C-32, Rio de Janeiro 22280-020, Brazil;

Strongyloidiasis is a parasitic infestation caused by the helminth Strongyloides stercoralis. It is essentially gastrointestinal and in general asymptomatic but can sometimes present with skin signs. Immunocompromised patients can develop the disseminated form of the disease due to the parasite's opportunistic behavior, as in cases of coinfection by the human T-lymphotropic type 1 virus (HTLV-1). Read More

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December 2018
4 Reads

Parasitic contamination of commonly consumed vegetables in two markets in Ghana.

Ghana Med J 2018 Jun;52(2):88-93

Epidemiology Unit, Ensign College of Public Health, Akosombo, Kpong, Ghana.

Introduction: Fresh vegetables are an important source of vital nutrients. Poor farming practices and improper washing put consumers at risk of parasitic infections. This study explored the presence of parasitic contamination of commonly-consumed vegetables procured from two markets in Ghana. Read More

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https://www.ajol.info/index.php/gmj/article/view/174669
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http://dx.doi.org/10.4314/gmj.v52i2.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326541PMC
June 2018
6 Reads

Epidemiology of Strongyloides stercoralis infection in Bolivian patients at high risk of complications.

PLoS Negl Trop Dis 2019 01 17;13(1):e0007028. Epub 2019 Jan 17.

Division of Tropical and Humanitarian Medicine, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

Background: Strongyloidiasis can be fatal in immunocompromised patients, but few epidemiological studies investigated the burden of this neglected tropical disease among these populations, particularly in low- and middle-income countries such as Bolivia. This study aimed to fill in this gap by estimating prevalence rate and risk factors associated with strongyloidiasis among patients at high risk of complications.

Methods: A cross-sectional study was carried out in Santa Cruz (elevation 400 meters, tropical climate) and Cochabamba (elevation 2,500 meters, temperate climate), among patients with cancer, HIV infection and rheumatic or hematologic disease, using four coproparasitological techniques and one serological (ELISA) test. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007028
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http://dx.doi.org/10.1371/journal.pntd.0007028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353209PMC
January 2019
7 Reads

Coexistent Helminth Infection-Mediated Modulation of Chemokine Responses in Latent Tuberculosis.

J Immunol 2019 Mar 16;202(5):1494-1500. Epub 2019 Jan 16.

National Institutes of Health-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India 600031;

Coexistent helminth infections are known to modulate T cell and cytokine responses in latent infection with However, their role in modulating chemokine responses in latent tuberculosis (LTB) has not been explored. Because chemokines play a vital role in the protective immune responses in LTB, we postulated that coexistent helminth infection could modulate chemokine production in helminth-LTB coinfection. To test this, we measured the levels of a panel of CC and CXC chemokines at baseline and following mycobacterial Ag or mitogen stimulation in individuals with LTB with (LTB) or without (LTB) infection and in individuals without both infections, healthy controls (HC). Read More

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801190
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http://dx.doi.org/10.4049/jimmunol.1801190DOI Listing
March 2019
4 Reads

Central nervous system Strongyloides stercoralis. A case report.

Turk Neurosurg 2018 Sep 28. Epub 2018 Sep 28.

Medifema Hospital.

Strongyloidiasis is an infestation caused by the intestinal nematode Strongyloides stercoralis. It is potentially fatal in immuno-compromised hosts due to its capacity to cause an overwhelming hyperinfestation however infested healthy individuals are usually asymptomatic. Hyperinfestation is extremely rare in the Central Nervous System (CNS) and usually limited to the gastrointestinal tract or lungs. Read More

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http://dx.doi.org/10.5137/1019-5149.JTN.22886-18.2DOI Listing
September 2018
3 Reads

Prevalence of parasitic contamination of raw vegetables in Nakhon Si Thammarat province, southern Thailand.

BMC Public Health 2019 Jan 8;19(1):34. Epub 2019 Jan 8.

Department of Tropical Pathology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

Background: Soil-transmitted helminth (STH) infections are major public health problems in poor and developing countries that require fecal contamination of the environment for transmission. The consumption of raw vegetables without proper washing is one of the main routes of intestinal parasite acquisition. Therefore, this study was designed to detect the prevalence of intestinal parasitic contamination in commonly consumed raw vegetables sold in three central open-air markets in Nakhon Si Thammarat province, southern Thailand. Read More

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http://dx.doi.org/10.1186/s12889-018-6358-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323832PMC
January 2019
1 Read

Prevalence and associated risk factors of infection in Lower Myanmar.

Trop Med Health 2018 18;46:43. Epub 2018 Dec 18.

2Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692 Japan.

Background: Strongyloidiasis is prevalent in Southeast Asian regions along with other soil-transmitted helminthiases, but only limited present-day data was available for Myanmar.

Methods: A prevalence survey for infection was conducted among villagers in rural areas of three townships located in the Lower Myanmar during 2014-2016 by agar plate culture method in combination with specific identification by molecular assays. Risk factors associated with infection were assessed by analyzing questionnaires obtained from study participants. Read More

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http://dx.doi.org/10.1186/s41182-018-0126-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299610PMC
December 2018
1 Read

Is Strongyloides seropositivity associated with diabetes mellitus? A retrospective case-control study in an East London NHS Trust.

Trans R Soc Trop Med Hyg 2018 Dec 28. Epub 2018 Dec 28.

Division of Infection, Barts Health NHS Trust, London, United Kingdom.

Background: The association between diabetes and Strongyloides stercoralis remains controversial. We conducted a case-control study examining the association between diabetes and Strongyloides seropositivity in a large UK centre.

Methods: Between January 2013 and October 2016, cases and controls were identified by positive and negative Strongyloides serology, respectively. Read More

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http://dx.doi.org/10.1093/trstmh/try132DOI Listing
December 2018
1 Read

Rhabditiform larvae of Strongyloides stercoralis hatching in a bronchoalveolar lavage specimen.

Diagn Cytopathol 2018 Dec 28. Epub 2018 Dec 28.

The Icahn School of Medicine at Mount Sinai, New York, New York.

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http://doi.wiley.com/10.1002/dc.24115
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http://dx.doi.org/10.1002/dc.24115DOI Listing
December 2018
10 Reads

Donor-derived strongyloidiasis in a Saudi pediatric kidney transplant recipient: A case report and mini-review.

Pediatr Transplant 2018 Dec 21:e13315. Epub 2018 Dec 21.

Division of Pediatric Infectious Diseases, King Abdullah Specialized Children's Hospital (KASCH), National Guard Health Affairs, Riyadh, Saudi Arabia.

S. stercoralis infection has been identified as a donor-derived infection in cases of solid organ transplant among recipients with no prior risk factor for parasitic exposure. Worldwide and regional reports from the adult kidney transplant population highlight this indirect method of infection and caution about delayed diagnosis, severe complications, and death related to donor-derived S. Read More

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http://doi.wiley.com/10.1111/petr.13315
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http://dx.doi.org/10.1111/petr.13315DOI Listing
December 2018
9 Reads

IgG reactivity with 40-35 kDa soluble and membrane antigen of Strongyloides venezuelensis in immunocompromised patients.

Acta Trop 2019 Feb 12;190:357-360. Epub 2018 Dec 12.

Laboratório de Investigação Médica (LIM/06 - Laboratório de Imunopatologia da Esquistossomose), Hospital das Clínicas da Faculdade de Medicina, USP, São Paulo, Brazil; Instituto de Medicina Tropical de São Paulo, USP, São Paulo, Brazil.

Immunocompromised patients constitute a risk group for the development of severe clinical forms of human strongyloidiasis. The diagnosis of this infection is primarily performed by parasitological techniques, but with low sensitivity. Serological techniques appear as an alternative, especially with heterologous antigens use. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0001706X183034
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http://dx.doi.org/10.1016/j.actatropica.2018.12.020DOI Listing
February 2019
8 Reads

Strongyloides stercoralis infection in imported and local dogs in Switzerland: from clinics to molecular genetics.

Parasitol Res 2019 Jan 14;118(1):255-266. Epub 2018 Dec 14.

Small Animal Clinic, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Strongyloides stercoralis is a worldwide-distributed intestinal nematode affecting mainly humans and dogs. Canine strongyloidosis is generally characterised by diarrhoea, malabsorption and bronchopneumonia, and may be fatal in cases of impaired immunity. In recent years, molecular and epidemiological studies suggested that host-adapted populations of S. Read More

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http://link.springer.com/10.1007/s00436-018-6173-3
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http://dx.doi.org/10.1007/s00436-018-6173-3DOI Listing
January 2019
1 Read

Spectrum of parasitic infections in centrifuged urine sediments from a newly developed tertiary care centre in Central India.

J Parasit Dis 2018 Dec 29;42(4):608-615. Epub 2018 Oct 29.

3Department of Microbiology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, MP 462024 India.

Detection of urinary parasites is relatively rare and incidental finding in routine urine examination. Common urinary parasitic infections as described in literature include Trichomonas, and Microfilaria. is known to cause vaginitis and urethritis, and may be found in urine sediments. Read More

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http://dx.doi.org/10.1007/s12639-018-1043-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261132PMC
December 2018
15 Reads

[Purpura due to Strongyloides stercoralis in an immunocompetent patient].

Rev Chilena Infectol 2018 Aug;35(4):445-447

Escuela de Medicina Humana, Universidad Científica del Sur, Lima, Perú.

Infection with Strongyloides stercoralis is a common parasitic infection in tropical and subtropical regions, including the Peruvian Amazon. The clinical manifestations are varied in patients with immunocompromised disease, and the systemic spread of the disease is frequent, compromising different organs and systems. Cutaneous manifestations are infrequent, being described in patients with some degree of immunosuppression. Read More

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http://dx.doi.org/10.4067/s0716-10182018000400445DOI Listing
August 2018
1 Read

Coinfections between Persistent Parasitic Neglected Tropical Diseases and Viral Infections among Prisoners from Sub-Saharan Africa and Latin America.

J Trop Med 2018 6;2018:7218534. Epub 2018 Nov 6.

Division of Prison Health, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

In Swiss prisons, more than 70% of detained people are foreigners and over one-third originate from sub-Saharan Africa or Latin America. These two regions are endemic for various tropical diseases and viral infections, which persist after migration to nonendemic countries. Parasitic infections (schistosomiasis; strongyloidiasis) and cooccurrent viral infections (HIV, hepatitis B (HBV), and hepatitis C (HCV)) are especially of concern for clinical care but have been neglected in empirical research. Read More

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https://www.hindawi.com/journals/jtm/2018/7218534/
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http://dx.doi.org/10.1155/2018/7218534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247427PMC
November 2018
2 Reads

Strongyloides venezuelensis infection augments arterial blood pressure in male wistar rats.

Acta Trop 2019 Feb 6;190:350-355. Epub 2018 Dec 6.

ICBS- Instituto de Ciências Biológicas e da Saúde, UFMT- Universidade Federal de Mato Grosso, Barra do Garças, Mato Grosso, Brazil. Electronic address:

Strongyloidiasis is an intestinal parasitosis that occurs in humans infected by Strongyloides stercoralis mostly. At its acute phase, symptoms like constipation, diarrhea and abdominal pain can be observed, but become asymptomatic for a long time, until an immunosuppression will start a hyperinfection and the dissemination of the disease, prevalent on the elderly population in tropical countries. Ivermectina treatment is the currently choice for this disease, due to its great efficacy and the results reported. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.12.007DOI Listing
February 2019
1 Read

A diagnostic study comparing conventional and real-time PCR for Strongyloides stercoralis on urine and on faecal samples.

Acta Trop 2019 Feb 3;190:284-287. Epub 2018 Dec 3.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, 37024, Italy.

Strongyloides stercoralis is a soil-transmitted helminth with a wide distribution in tropical and subtropical areas. The diagnosis of S. stercoralisinfection can be challenging, due to the low sensitivity of microscopic examination of stool samples and coproculture. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.12.001DOI Listing
February 2019
8 Reads

Strongyloides stercoralis infection in a migrant on dialysis.

J Travel Med 2018 Jan;25(1)

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, Negrar, Verona, Italy.

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http://dx.doi.org/10.1093/jtm/tay143DOI Listing
January 2018
3 Reads

Seroepidemiological aspects of human infection by Strongyloides stercoralis in Alfenas, southern Minas Gerais, Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):855-859

Laboratório de Diagnóstico de Parasitoses, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.

Introduction: In most Strongyloides stercoralis infected individuals, nematoidosis occurs asymptomatically, but in immunocompromised patients, it can cause hyperinfection. Serological techniques seem to be a good alternative for detecting this parasite.

Methods: The frequency of seropositivity for strongyloidiasis in Alfenas, MG, was estimated using the enzyme linked immunosorbent assay on blood samples, between May and August of 2015. Read More

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http://dx.doi.org/10.1590/0037-8682-0090-2018DOI Listing
February 2019
2 Reads

Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome.

Case Rep Infect Dis 2018 28;2018:6870768. Epub 2018 Oct 28.

Department of Medicine, Poona Hospital and Research Center, Pune, Maharashtra, India.

Parasitic infections such as and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease. Read More

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https://www.hindawi.com/journals/criid/2018/6870768/
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http://dx.doi.org/10.1155/2018/6870768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230409PMC
October 2018
6 Reads

High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study.

PLoS Negl Trop Dis 2018 11 29;12(11):e0007010. Epub 2018 Nov 29.

ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.

Background: Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, using our institution's serum bank. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289465PMC
November 2018
2 Reads

Gastroduodenal involvement in disseminated strongyloidiasis.

JGH Open 2018 Apr 22;2(2):75-76. Epub 2018 Feb 22.

Department of Gastroenterology Kobe City Medical Center General Hospital Kobe Japan.

Here, we report the case of a 57-year-old Peruvian man on long-term corticosteroid therapy for a drug allergy and proton pump inhibitors for chronic dyspepsia symptoms. Upper gastrointestinal endoscopy showed multiple white granular lesions and widespread erosions in the stomach. Our findings indicate that gastric strongyloidiasis should be carefully considered in high-risk patients even if endoscopic findings are nonspecific. Read More

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http://dx.doi.org/10.1002/jgh3.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206995PMC
April 2018
1 Read

Serodiagnosis and early detection of Strongyloides stercoralis infection.

J Microbiol Immunol Infect 2018 Oct 11. Epub 2018 Oct 11.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia. Electronic address:

Strongyloidiasis is a major neglected tropical disease with the potential of causing lifelong infection and mortality. One of the ways for effective control of this disease is developing improved diagnostics, particularly using serological approaches. A serological test can achieve high diagnostic sensitivity and specificity, has the potential for point-of-care translation, and can be used as a screening tool for early detection. Read More

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http://dx.doi.org/10.1016/j.jmii.2018.10.001DOI Listing
October 2018
1 Read

Efficacy of ivermectin to control Strongyloides stercoralis infection in sheltered dogs.

Acta Trop 2019 Feb 19;190:204-209. Epub 2018 Nov 19.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy; Dipartimento di Diagnostica e Sanità pubblica, Università degli Studi di Verona, Italy.

In dogs, information on treatments against S. stercoralis infection is rare and anecdotal. The aim of the present work was to evaluate the treatment outcome of S. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.11.014DOI Listing
February 2019
14 Reads

Streptococcus pyogenes bacteremia and toxic shock syndrome related to Strongyloides stercoralis hyperinfection: a case report.

J Med Case Rep 2018 Nov 22;12(1):346. Epub 2018 Nov 22.

Reference Parasitology Laboratory, Central Laboratories, Public Health Services, Ministry of Health, Jerusalem, Israel.

Background: We describe a patient with Strongyloides stercoralis hyperinfection associated with Streptococcus pyogenes and with streptococcal toxic shock syndrome. To the best of our knowledge this association has not been previously described.

Case Presentation: A 78 year-old Israeli man, who was born in Iraq but lived in Israel for 66 years, presented with multi-organ failure including acute kidney and hepatic injury, coagulopathy, and lactic acidosis. Read More

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http://dx.doi.org/10.1186/s13256-018-1885-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249898PMC
November 2018
15 Reads

Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem.

Am J Trop Med Hyg 2019 Jan;100(1):130-134

Division of Infectious Diseases, Department of Medicine, St. Joseph's Health Centre, Toronto, Canada.

Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the CNS sample in one case. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0813
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http://dx.doi.org/10.4269/ajtmh.18-0813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335887PMC
January 2019
22 Reads

Metabolic consequences of concomitant Strongyloides stercoralis infection in Type 2 diabetes mellitus.

Clin Infect Dis 2018 Nov 8. Epub 2018 Nov 8.

National Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.

Background: Human and animal studies have demonstrated that helminth infections are associated with a decreased prevalence of Type 2 diabetes mellitus (T2DM). However, very little is known about the biochemical and immunological interactions between the two.

Methods: To assess the relationship between a soil-transmitted helminth, Strongyloides stercoralis (Ss) and T2DM, we examined a variety of analytes associated with glycemic control, metabolic processes and T cell driven inflammation at the time of Ss diagnosis and then 6 months after definitive anthelmintic treatment. Read More

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http://dx.doi.org/10.1093/cid/ciy935DOI Listing
November 2018
5 Reads

Elevated Systemic and Parasite-Antigen Stimulated Levels of Type III IFNs in a Chronic Helminth Infection and Reversal Following Anthelmintic Treatment.

Front Immunol 2018 23;9:2353. Epub 2018 Oct 23.

National Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.

Type III IFNs are important players in immunity to viral and bacterial infections. However, their association with helminth infections has not been examined. To explore the association of Type III IFNs with () infection, we examined the systemic levels of IFN lambda-1, IFN lambda-2 and IFN lambda-3, IL-10, and CXCL10/IP-10 in infected (INF, = 44), helminth-uninfected (UN, = 44) and in post-treatment INF individuals. Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02353
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http://dx.doi.org/10.3389/fimmu.2018.02353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205947PMC
October 2018
7 Reads

Accuracy of Urine and Serum Assays for the Diagnosis of Strongyloidiasis by Three Enzyme-Linked Immunosorbent Assay Protocols.

Am J Trop Med Hyg 2019 Jan;100(1):127-129

Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand.

To evaluate the accuracy and reliability of urine assay for the diagnosis of strongyloidiasis, three different immunoassays were used to assess the diagnostic accuracy of anti- immunoglobulin G (IgG) in urine and compared with those in serum samples. Analyses by InBios enzyme-linked immunosorbent assay (ELISA) kit (recombinant NIE antigen), SciMedx ELISA kit ( antigen), and our in-house ELISA ( antigen) yielded comparable diagnostic performances between urine and serum assays. Levels of -specific IgG in urine significantly correlated with those in serum. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0569
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http://dx.doi.org/10.4269/ajtmh.18-0569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335925PMC
January 2019
10 Reads

Terror in the dirt: Sensory determinants of host seeking in soil-transmitted mammalian-parasitic nematodes.

Int J Parasitol Drugs Drug Resist 2018 12 26;8(3):496-510. Epub 2018 Oct 26.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA. Electronic address:

Infection with gastrointestinal parasitic nematodes is a major cause of chronic morbidity and economic burden around the world, particularly in low-resource settings. Some parasitic nematode species, including the human-parasitic threadworm Strongyloides stercoralis and human-parasitic hookworms in the genera Ancylostoma and Necator, feature a soil-dwelling infective larval stage that seeks out hosts for infection using a variety of host-emitted sensory cues. Here, we review our current understanding of the behavioral responses of soil-dwelling infective larvae to host-emitted sensory cues, and the molecular and cellular mechanisms that mediate these responses. Read More

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https://www.researchgate.net/scientific-contributions/135143
Web Search
https://linkinghub.elsevier.com/retrieve/pii/S22113207183011
Publisher Site
http://dx.doi.org/10.1016/j.ijpddr.2018.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287541PMC
December 2018
10 Reads

Selected aspects of helminth infections Schistosoma sp., Ascaris lumbricoides, Strongyloides stercoralis in individuals diagnosed with human immunodeficiency virus (HIV) infection

Przegl Epidemiol 2018 ;72(3):349-361

University of Warsaw, Faculty of Biology, Department of Parasitology

Co-infections of HIV and other pathogens constitute an important clinical and epidemiological problem. Many studies have played attention to opportunistic co-infections due to the fact that they are used as an indicator for development of AIDS and are present on the all continents. However, in HIV-infected patients helminth infections, which are not aetiologic agents of opportunistic infections, are becoming more and more important. Read More

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http://www.przeglepidemiol.pzh.gov.pl/pobierz-artykul?id=222
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http://dx.doi.org/10.32394/pe.72.3.11DOI Listing
January 2018
11 Reads

Severe strongyloidiasis and systemic vasculitis: comorbidity, association or both? Case-based review.

Rheumatol Int 2018 Dec 23;38(12):2315-2321. Epub 2018 Oct 23.

Clinic of Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia.

A possible association between strongyloidiasis and systemic vasculitis is rarely reported in the literature. We report the case of a patient with severe strongyloidiasis and an angiographic finding consistent with polyarteritis nodosa. Diagnosis of strongyloidiasis was made by finding of larvae and adult parasites in samples of the upper gastrointestinal tract mucosa and stool. Read More

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http://link.springer.com/10.1007/s00296-018-4178-y
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http://dx.doi.org/10.1007/s00296-018-4178-yDOI Listing
December 2018
13 Reads

A comprehensive analysis of the faecal microbiome and metabolome of Strongyloides stercoralis infected volunteers from a non-endemic area.

Sci Rep 2018 Oct 23;8(1):15651. Epub 2018 Oct 23.

Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.

Data from recent studies support the hypothesis that infections by human gastrointestinal (GI) helminths impact, directly and/or indirectly, on the composition of the host gut microbial flora. However, to the best of our knowledge, these studies have been conducted in helminth-endemic areas with multi-helminth infections and/or in volunteers with underlying gut disorders. Therefore, in this study, we explore the impact of natural mono-infections by the human parasite Strongyloides stercoralis on the faecal microbiota and metabolic profiles of a cohort of human volunteers from a non-endemic area of northern Italy (S+), pre- and post-anthelmintic treatment, and compare the findings with data obtained from a cohort of uninfected controls from the same geographical area (S-). Read More

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http://www.nature.com/articles/s41598-018-33937-3
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http://dx.doi.org/10.1038/s41598-018-33937-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199319PMC
October 2018
10 Reads

[Severe infection: a case report].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Sep;30(4):479-480

Department of Laboratory Medicine, Fujian Provincial Hospital, Fuzhou 350001, China.

This paper reports a severe case of infection during routine sputum smear examinations, due to cough and shortness of breath, so as to improve clinicians' awareness of strongyloidiasis to avoid and reduce misdiagnosis and missed diagnosis. Read More

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http://dx.doi.org/10.16250/j.32.1374.2018214DOI Listing
September 2018
3 Reads

Prevalence of enteric parasitic infections among people living with HIV in Abeokuta, Nigeria.

Pan Afr Med J 2018 28;30:66. Epub 2018 May 28.

Department of Medical Microbiology & Parasitology, Ladoke Akintola University of Technology, Osogbo, Nigeria.

Introduction: Enteric parasitic infections have been increasingly recognized as etiology of life-threatening chronic diarrhea in PLWHA in sub-Saharan Africa. This study investigated the prevalence and burden of intestinal parasitic infection among PLWHA in Abeokuta, southwest Nigeria.

Methods: Freshly passed stool samples were collected from PLWHA. Read More

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http://www.panafrican-med-journal.com/content/article/30/66/
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http://dx.doi.org/10.11604/pamj.2018.30.66.13160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191249PMC
October 2018
11 Reads

Impact of the health education and preventive equipment package (HEPEP) on prevention of Strongyloides stercoralis infection among rural communities in Northeast Thailand: a cluster randomized controlled trial.

BMC Public Health 2018 Oct 19;18(1):1184. Epub 2018 Oct 19.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Strongyloidiasis is prevalent in northeast Thailand. This study aimed to evaluate the impact of the Health Education and Preventive Equipment Package (HEPEP), a package we developed to improve awareness and aid in the prevention of Strongyloides stercoralis infection among rural communities in northeast Thailand.

Methods: This was an intervention trial conducted in 12 villages (six interventions and six controls) in rural areas of northeast Thailand from March 2016 to September 2017. Read More

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http://dx.doi.org/10.1186/s12889-018-6081-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194667PMC
October 2018
3 Reads

Prevalence of Strongyloides stercoralis infection and hyperinfection syndrome among renal allograft recipients in Central Europe.

Sci Rep 2018 Oct 18;8(1):15406. Epub 2018 Oct 18.

Department of Internal Medicine III; Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.

Strongyloides stercoralis is not hyperendemic in European countries but has been increasing in prevalence due to migration and travel. The infection is characterized by a mostly asymptomatic course or nonspecific symptoms in healthy subjects. However, immunosuppression or chemotherapy have been described as leading triggers for Strongyloides stercoralis hyperinfection syndrome and may have a fatal course. Read More

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http://www.nature.com/articles/s41598-018-33775-3
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http://dx.doi.org/10.1038/s41598-018-33775-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194009PMC
October 2018
10 Reads

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.

Wien Klin Wochenschr 2018 Oct 15;130(19-20):581-588. Epub 2018 Oct 15.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.

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http://dx.doi.org/10.1007/s00508-018-1395-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209003PMC
October 2018
4 Reads

An unusual rash: Strongyloides stercoralis presenting as larva currens in a 12-year-old girl with Crohn's disease.

J Paediatr Child Health 2018 Oct 13. Epub 2018 Oct 13.

Alice Springs Hospital, Alice Springs, Northern Territory, Australia.

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http://dx.doi.org/10.1111/jpc.14265DOI Listing
October 2018

Knowledge, attitude and practice with respect to soil contamination by Soil-Transmitted Helminths in Ibadan, Southwestern Nigeria.

Parasite Epidemiol Control 2018 Nov 24;3(4):e00075. Epub 2018 Sep 24.

Parasitology Unit, Department of Zoology, Faculty of Science, University of Ibadan, Oyo State, Nigeria.

, , and , the four major Soil-transmitted helminths (STHs) and also infect humans worldwide. Most studies on Soil-transmitted helminths (STHs) carried out in Ibadan were faecal examination based while relatively few soil examination based studies were carried out mostly around school premises using limited number of sampling locations. This study was therefore designed to assess the level of soil contamination with STH and associated risk factors in the eleven local government areas of Ibadan. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24056731183002
Publisher Site
http://dx.doi.org/10.1016/j.parepi.2018.e00075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171486PMC
November 2018
3 Reads