2,814 results match your criteria Strongyloides Stercoralis


Cross-sectional study on intestinal parasite infections in different ecological zones of the Department of La Paz, Bolivia.

One Health 2021 Dec 27;13:100271. Epub 2021 May 27.

Dipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Roma, Italy.

We performed a cross-sectional parasitological survey to assess the prevalence of protozoa and helminth infection among 275 school-age children (SAC) living in rural and peri-urban areas located in different ecological zones of the Department of La Paz, Bolivia. Public health activities for the control of STH, based on the biannual administration of mebendazole to preschool and school children are implemented at national level since 1986. We found an overall prevalence of 82. Read More

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December 2021

Is Gastric Involvement by Strongyloides stercoralis in an Immunocompetent Patient a Common Finding? A Case Report and Review of the Literature.

Acta Parasitol 2021 Jun 18. Epub 2021 Jun 18.

St Mary's Hospital Lacor, Gulu, Uganda.

Purpose: Gastric infection with Strongyloides stercoralis (SS) usually occurs in immunocompromised patients. The unexpected observation of this parasite in an otherwise healthy young lady who had undergone upper endoscopy and biopsy sampling of the gastro-duodenal mucosa, prompted us to review the literature to ascertain the conditions favouring gastric colonization by SS.

Methods: Pathology files of gastroduodenal biopsies received at St. Read More

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Reactivation of latent infections in solid organ transplant recipients from sub-Saharan Africa: What should be remembered?

Transplant Rev (Orlando) 2021 Jun 2;35(4):100632. Epub 2021 Jun 2.

Unit of Infectious Diseases, University Hospital "12 de Octubre", Research Institute Hospital "12 de Octubre" (imas12), Madrid, Spain; Department of Medicine, Universidad Complutense, Madrid, Spain.

International migration from Sub-Saharan African countries to the European Union and the United States has significantly increased over the past decades. Although the vast majority of these immigrants are young and healthy people, a minority can be affected by chronic conditions eventually leading to solid organ transplantation (SOT). Importantly, these candidates can bear geographically restricted fungal and parasitic latent infections that can reactivate after the procedure. Read More

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Reactivation of Strongyloides stercoralis in patients with SARS-CoV-2 pneumonia receiving dexamethasone.

Med Clin (Barc) 2021 May 27. Epub 2021 May 27.

Departamento de Medicina Interna, Hospital Sant Joan Despí Moisès Broggi, Barcelona. Electronic address:

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The occurence of endoparasites in Slovakian household dogs and cats.

Vet Res Commun 2021 Jun 11. Epub 2021 Jun 11.

University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic.

Pets play a pivotal role as definitive or reservoir hosts for many zoonotic parasites. Dogs and cats without any clinical signs may be a carrier for the infection. In a one-year study, collected fecal samples of 257 dogs and 50 cats were examined coproscopically for endoparasite infections. Read More

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Microscopic and molecular evaluation of Strongyloides venezuelensis in an experimental life cycle using Wistar rats.

Biomedica 2021 05 31;41(Supl. 1):35-46. Epub 2021 May 31.

Área de Parasitología y Bioterios, Gestión de Investigación, Desarrollo e Innovación, Instituto Nacional de Investigación en Salud Pública Leopoldo Izquieta Pérez, Quito, Ecuador.

Introduction: Strongyloides venezuelensis is a nematode whose natural host is rats. It is used as a model for the investigation of human strongyloidiasis caused by S. stercoralis. Read More

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Prevalence, risk factors and impact of cellular immunity on intestinal parasitosis among people living with HIV at Auchi, Edo State, Nigeria.

Int J STD AIDS 2021 Jun 9:9564624211020984. Epub 2021 Jun 9.

Department of Global Health and Development, 4906London School of Hygiene and Tropical Medicine, London, UK.

This study was sought to determine the impact of CD4 T-cell count and associated risk factors with intestinal parasitosis in people living with HIV (PLHIV) in Central Hospital, Auchi, Edo State, Nigeria. One hundred and seventy (170) HIV-seropositive subjects were enrolled in the study from 24 August 2015 to 22 January 2016. Sociodemographic data were assessed using structured questionnaires. Read More

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Eosinophilic appendicitis due to : a challenging differential diagnosis for clinicians.

BMJ Case Rep 2021 Jun 1;14(6). Epub 2021 Jun 1.

Department of Histopathology, Hospital Universitario de Móstoles, Móstoles, Madrid, Spain.

A 45-year-old man presents with 48-hour status of high temperature, cough and dyspnoea. In the context of pandemic, the patient is initially diagnosed with COVID-19 syndrome. Later, the laboratory and ultrasound study supported acute appendicitis diagnosis. Read More

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First demonstration of Strongyloides parasite from an imported pet meerkat - Possibly a novel species in the stercoralis/procyonis group.

Parasitol Int 2021 May 30;84:102399. Epub 2021 May 30.

Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, 889-1692 Miyazaki, Japan. Electronic address:

Strongyloides is a genus of parasitic nematodes of vertebrates that contains over 50 species, each with a variable host range. A recent molecular phylogenetic analysis on this genus showed that Strongyloides spp. from various carnivore hosts form a strongly supported clade together with Strongyloides stercoralis, a major pathogen of humans and dogs (named the "stercoralis/procyonis group"). Read More

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Combination therapy for disseminated strongyloidiasis with associated vancomycin-resistant, linezolid-intermediate Enterococcus faecium meningitis: A case report.

J Clin Pharm Ther 2021 Jun 2. Epub 2021 Jun 2.

Department of Pharmacy Services, Saint Joseph Hospital, Lexington, KY, USA.

What Is Known And Objective: The rhabditid nematode Strongyloides stercoralis is the major causative agent of disseminated strongyloidiasis (DS). In rare cases, DS has caused enterococcal meningitis. If DS-associated vancomycin-resistant Enterococcus faecium (VRE) meningitis is suspected, combination antibiotic therapy should be considered. Read More

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-Specific IgE Phage cDNA Clones and Development of a Novel ELISA for Strongyloidiasis.

Diagnostics (Basel) 2021 May 28;11(6). Epub 2021 May 28.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang 11800, Malaysia.

Strongyloidiasis, caused mainly by the nematode , is prevalent worldwide and potentially fatal in immunosuppressed patients. We report on a new IgE biomarker to diagnose infection. Sera from two groups infected with served as positive samples: Group 1A, in which infection was confirmed by stool-microscopy and/or stool-polymerase chain reaction (PCR) and was seropositive by an IgG-enzyme linked immunosorbent assay (ELISA) and an IgG4 rapid test, and Group 1B in which infection was confirmed by stool-PCR but was seronegative. Read More

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Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2.

PLoS Negl Trop Dis 2021 Jun 1;15(6):e0009361. Epub 2021 Jun 1.

Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.

Background: Helminths can modulate the host immune response to Plasmodium falciparum and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria vaccine candidate, a recombinant protein consisting of conserved domains of GLURP and MSP3, two asexual blood-stage antigens of P. falciparum. Read More

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A new antigen detection ELISA for the diagnosis of Strongyloides infection.

Acta Trop 2021 May 28;221:105986. Epub 2021 May 28.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia (USM), 11800 Penang, Malaysia. Electronic address:

Serodiagnosis is an essential component of the laboratory diagnosis of Strongyloides infection and is usually performed using an indirect IgG antibody test. A direct antigen detection method can complement the IgG assay, particularly for detecting early infection and post-treatment follow-up. In the present study, a recombinant scFv monoclonal antibody against NIE recombinant protein (rMAb23) that we had previously produced was used to develop a Strongyloides antigen detection ELISA (SsAg-ELISA). Read More

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Comparison of Strongyloides-specific IgG enzyme immunoassays for laboratory detection of Strongyloides stercoralis infection.

Pathology 2021 May 25. Epub 2021 May 25.

Serology and Virology Division (SAViD), NSW Health Pathology Randwick, Level 4, Prince of Wales Hospital, Randwick, NSW, Australia; School of Medical Sciences and School of Women's and Children's Health, Faculty of Medicine, School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Randwick, NSW, Australia. Electronic address:

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Histopathological diagnosis of strongyloidiasis hyperinfection in Tunisian patient with hodgkin lymphoma: Case report.

Ann Med Surg (Lond) 2021 Jun 13;66:102367. Epub 2021 May 13.

Pathology Department, Farhat Hached University Hospital, 4000, Sousse, Tunisia.

Introduction: , an intestinal nematode, is commonly dispersed throughout the tropical and subtropical regions. infection typically contributes to an asymptomatic chronic disease which can remain hidden for decades. However, in immunocompromised patients, the hyperinfection can take place, causing high mortality rates. Read More

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Control programs for strongyloidiasis in areas of high endemicity: an economic analysis of different approaches.

Infect Dis Poverty 2021 May 25;10(1):76. Epub 2021 May 25.

Department of Health Sciences, University of Florence, Florence, Italy.

Background: Implementation of control programmes for Strongyloides stercoralis infection is among the targets of the World Health Organization Roadmap to 2030. Aim of this work was to evaluate the possible impact in terms of economic resources and health status of two different strategies of preventive chemotherapy (PC) compared to the current situation (strategy A, no PC): administration of ivermectin to school-age children (SAC) and adults (strategy B) versus ivermectin to SAC only (strategy C).

Methods: The study was conducted at the IRCCS Sacro Cuore Don Calabria hospital, Negrar di Valpolicella, Verona, Italy, at the University of Florence, Italy, and at the WHO, Geneva, Switzerland, from May 2020 to April 2021. Read More

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Canine gastrointestinal parasites as a potential source of zoonotic infections in Nigeria: A nationwide survey.

Prev Vet Med 2021 Jul 17;192:105385. Epub 2021 May 17.

Laboratory of Parasitology, Institute of Natural Resources and Agrobiology of Salamanca (IRNASA-CSIC), C/ Cordel de Merinas 40-52, 37008, Salamanca, Spain.

Dog feces may contain zoonotic parasites that contaminate the environment and serve as a potential source of infection to animals and humans. In this study, microscopic and molecular analyses were used to estimate the prevalence and intensity of gastrointestinal (GI) parasites and assess the risk factors for infection in 948 dogs in three climatically distinct zones of Nigeria. Zoonotic helminths including Strongyloides stercoralis, Ancylostoma braziliense, A. Read More

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Strongyloides Stercoralis in Acute Severe Ulcerative Colitis-A Triggering Nuisance or An Opportunistic Bystander?

Inflamm Bowel Dis 2021 May 21. Epub 2021 May 21.

Department of Gastroenterology, Post Graduate Institute of Medical Education & Research, Chandigarh,  India.

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Intestinal parasites among intellectually disabled individuals in Iran: a systematic review and meta-analysis.

Gut Pathog 2021 May 1;13(1):28. Epub 2021 May 1.

Toxoplasmosis Research Center, Department of Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Poor self-care skills and personal hygiene resulted from limitations in learning and understanding, put intellectually disabled individuals at greater risk for intestinal parasitic infections (IPIs). Despite several regional reports in Iran, the overall burden on IPIs among intellectually disabled individuals is poorly understood. Hence, the present study aimed to estimate the pooled prevalence of IPIs among intellectually disabled individuals in Iran. Read More

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The autochthonous cases of acute strongyloidiasis in the Moscow region.

Germs 2021 Mar 15;11(1):116-119. Epub 2021 Mar 15.

MD, PhD, Martsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov University, 119435 Moscow, Russia.

Introduction: At present, strongyloidiasis is considered by the World Health Organizaiton (WHO) as one of the most neglected diseases.

Case Report: A husband and a wife, both born in the Moscow region and never having traveled, initially presented with fever and unexplained peripheral eosinophilia. Parasitological examination revealed in feces samples. Read More

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Asymptomatic Intestinal Parasitic Infestations among Children Under Five Years in Selected Communities in the Ho Municipality, Ghana.

Ethiop J Health Sci 2020 Nov;30(6):867-874

Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.

Background: The study investigated intestinal parasitic infestations (IPIs) and possible risk factors associated with asymptomatic children under five (5) years in five (5) selected communities in the Ho Municipality.

Methods: The study design was cross- sectional, with a simple random sampling technique involving 150 asymptomatic children under 5 years from 5 selected communities (Klave, Hoe, Freetown, Dave and Godokpe) in the Ho Municipality. A questionnaire was used to obtain socio-demographics and other relevant parameters. Read More

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November 2020

Answer to May 2021 Photo Quiz.

J Clin Microbiol 2021 Apr 20;59(5). Epub 2021 Apr 20.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA

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Development of rSs-NIE-1 and rSs-IR Recombinant Antigen-Based Immunoblot for Detection of Antibody to Strongyloides stercoralis.

Am J Trop Med Hyg 2021 Apr 19. Epub 2021 Apr 19.

4Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.

Strongyloides stercoralis is a soil-transmitted nematode that can cause life-threatening conditions in immunocompromised persons. In the United States, strongyloidiasis should be considered mainly in immigrants, refugees, or travelers. The confirmatory laboratory diagnosis is usually performed by detecting larvae from the stool, duodenal material, and sputum. Read More

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Transcriptional profiles in Strongyloides stercoralis males reveal deviations from the Caenorhabditis sex determination model.

Sci Rep 2021 Apr 15;11(1):8254. Epub 2021 Apr 15.

Department of Biology, Millersville University of Pennsylvania, Millersville, PA, 17551, USA.

The human and canine parasitic nematode Strongyloides stercoralis utilizes an XX/XO sex determination system, with parasitic females reproducing by mitotic parthenogenesis and free-living males and females reproducing sexually. However, the genes controlling S. stercoralis sex determination and male development are unknown. Read More

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Preventive chemotherapy for the control of strongyloidiasis in school-age children: Estimating the ivermectin need.

PLoS Negl Trop Dis 2021 Apr 15;15(4):e0009314. Epub 2021 Apr 15.

Department of Infectious-Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy.

Background: Strongyloides stercoralis is a soil-transmitted helminth (STH) that affects approximately 600 million people worldwide. Interventions targeting S. stercoralis have not been implemented yet. Read More

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Correction: Severe Strongyloides stercoralis infection in kidney transplant recipients: A multicenter case-control study.

Authors:

PLoS Negl Trop Dis 2021 Apr 12;15(4):e0009342. Epub 2021 Apr 12.

[This corrects the article DOI: 10.1371/journal.pntd. Read More

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hyperinfection in a patient with acute lymphoblastic leukemia.

J Postgrad Med 2021 Apr-Jun;67(2):113-114

Department of Surgical Oncology, Institute of Medical Sciences and SUM Hospital, Bhubaneswar, Odisha, India.

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Strongyloides RNA-seq Browser: a web-based software platform for on-demand bioinformatics analyses of Strongyloides species.

G3 (Bethesda) 2021 May;11(5)

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Soil-transmitted gastrointestinal parasitic nematodes infect approximately 1 billion people worldwide, predominantly in low-resource communities. Skin-penetrating gastrointestinal nematodes in the genus Strongyloides are emerging as model systems for mechanistic studies of soil-transmitted helminths due to the growing availability of functional genomics tools for these species. To facilitate future genomics studies of Strongyloides species, we have designed a web-based application, the Strongyloides RNA-seq Browser, that provides an open source, user-friendly portal for accessing and analyzing Strongyloides genomic expression data. Read More

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Diminished circulating levels of angiogenic factors and RAGE ligands in helminth-diabetes comorbidity and reversal following anthelmintic treatment.

J Infect Dis 2021 Apr 2. Epub 2021 Apr 2.

National Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India and Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Background: Various epidemiological and experimental studies propose that helminths could play a preventive role against the progression of Type 2 diabetes mellitus (T2DM). T2DM induces microvascular and large vessel complications mediated by elevated levels of angiogenic factors and soluble RAGE ligands. However, the interactions between helminths and host angiogenic factors and RAGE ligands are unexplored. Read More

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