4,202 results match your criteria Strongyloides Stercoralis


IgG reactivity with 40-35 kDa soluble and membrane antigen of Strongyloides venezuelensis in immunocompromised patients.

Acta Trop 2018 Dec 12. Epub 2018 Dec 12.

Laboratório de Investigação Médica (LIM/06 - Laboratório de Imunopatologia da esquistossomose), Hospital das Clínicas da Faculdade de Medicina, USP, São Paulo, Brazil; Instituto de Medicina Tropical de São Paulo, USP, São Paulo, Brazil.

Immunocompromised patients constitute a risk group for the development of severe clinical forms of human strongyloidiasis. The diagnosis of this infection is primarily performed by parasitological techniques, but with low sensitivity. Serological techniques appear as an alternative, especially with heterologous antigens use. Read More

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December 2018
1 Read

Strongyloides stercoralis infection in imported and local dogs in Switzerland: from clinics to molecular genetics.

Parasitol Res 2018 Dec 14. Epub 2018 Dec 14.

Small Animal Clinic, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Strongyloides stercoralis is a worldwide-distributed intestinal nematode affecting mainly humans and dogs. Canine strongyloidosis is generally characterised by diarrhoea, malabsorption and bronchopneumonia, and may be fatal in cases of impaired immunity. In recent years, molecular and epidemiological studies suggested that host-adapted populations of S. Read More

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December 2018

Eosinophilia and Kidney Disease: More than Just an Incidental Finding?

J Clin Med 2018 Dec 8;7(12). Epub 2018 Dec 8.

Department of Internal Medicine IV (Nephrology and Hypertension), Medical University Innsbruck, 6020 Innsbruck, Austria.

Peripheral blood eosinophilia (PBE), defined as 500 eosinophils or above per microliter (µL) blood, is a condition that is not uncommon but often neglected in the management of patients with chronic kidney disease (CKD), acute kidney injury (AKI), or patients on renal replacement therapy (RRT). The nature of PBE in the context of kidney diseases is predominantly secondary or reactive and has to be distinguished from primary eosinophilic disorders. Nonetheless, the finding of persistent PBE can be a useful clue for the differential diagnosis of underdiagnosed entities and overlapping syndromes, such as eosinophilic granulomatosis with polyangiitis (EGPA), IgG4-related disease (IgG4-RD), acute interstitial nephritis (AIN), or the hypereosinophilic syndrome (HES). Read More

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December 2018

Spectrum of parasitic infections in centrifuged urine sediments from a newly developed tertiary care centre in Central India.

J Parasit Dis 2018 Dec 29;42(4):608-615. Epub 2018 Oct 29.

3Department of Microbiology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, MP 462024 India.

Detection of urinary parasites is relatively rare and incidental finding in routine urine examination. Common urinary parasitic infections as described in literature include Trichomonas, and Microfilaria. is known to cause vaginitis and urethritis, and may be found in urine sediments. Read More

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December 2018

[Purpura due to Strongyloides stercoralis in an immunocompetent patient].

Rev Chilena Infectol 2018 Aug;35(4):445-447

Escuela de Medicina Humana, Universidad Científica del Sur, Lima, Perú.

Infection with Strongyloides stercoralis is a common parasitic infection in tropical and subtropical regions, including the Peruvian Amazon. The clinical manifestations are varied in patients with immunocompromised disease, and the systemic spread of the disease is frequent, compromising different organs and systems. Cutaneous manifestations are infrequent, being described in patients with some degree of immunosuppression. Read More

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August 2018
1 Read

Coinfections between Persistent Parasitic Neglected Tropical Diseases and Viral Infections among Prisoners from Sub-Saharan Africa and Latin America.

J Trop Med 2018 6;2018:7218534. Epub 2018 Nov 6.

Division of Prison Health, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

In Swiss prisons, more than 70% of detained people are foreigners and over one-third originate from sub-Saharan Africa or Latin America. These two regions are endemic for various tropical diseases and viral infections, which persist after migration to nonendemic countries. Parasitic infections (schistosomiasis; strongyloidiasis) and cooccurrent viral infections (HIV, hepatitis B (HBV), and hepatitis C (HCV)) are especially of concern for clinical care but have been neglected in empirical research. Read More

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November 2018
1 Read

Strongyloides venezuelensis infection augments arterial blood pressure in male wistar rats.

Acta Trop 2018 Dec 6. Epub 2018 Dec 6.

ICBS- Instituto de Ciências Biológicas e da Saúde, UFMT- Universidade Federal de Mato Grosso, Barra do Garças, Mato Grosso, Brazil. Electronic address:

Strongyloidiasis is an intestinal parasitosis that occurs in humans infected by Strongyloides stercoralis mostly. At its acute phase, symptoms like constipation, diarrhea and abdominal pain can be observed, but become asymptomatic for a long time, until an immunosuppression will start a hyperinfection and the dissemination of the disease, prevalent on the elderly population in tropical countries. Ivermectina treatment is the currently choice for this disease, due to its great efficacy and the results reported. Read More

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December 2018

A diagnostic study comparing conventional and real-time PCR for Strongyloides stercoralis on urine and on faecal samples.

Acta Trop 2018 Dec 3;190:284-287. Epub 2018 Dec 3.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, 37024, Italy.

Strongyloides stercoralis is a soil-transmitted helminth with a wide distribution in tropical and subtropical areas. The diagnosis of S. stercoralisinfection can be challenging, due to the low sensitivity of microscopic examination of stool samples and coproculture. Read More

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December 2018
2 Reads

Strongyloides stercoralis infection in a migrant on dialysis.

J Travel Med 2018 Dec 6. Epub 2018 Dec 6.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria hospital, Via Sempreboni 5, 37024 Negrar, Verona, Italy.

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December 2018
1 Read

Seroepidemiological aspects of human infection by Strongyloides stercoralis in Alfenas, southern Minas Gerais, Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):855-859

Laboratório de Diagnóstico de Parasitoses, Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, MG, Brasil.

Introduction: In most Strongyloides stercoralis infected individuals, nematoidosis occurs asymptomatically, but in immunocompromised patients, it can cause hyperinfection. Serological techniques seem to be a good alternative for detecting this parasite.

Methods: The frequency of seropositivity for strongyloidiasis in Alfenas, MG, was estimated using the enzyme linked immunosorbent assay on blood samples, between May and August of 2015. Read More

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March 2018
1 Read

Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome.

Case Rep Infect Dis 2018 28;2018:6870768. Epub 2018 Oct 28.

Department of Medicine, Poona Hospital and Research Center, Pune, Maharashtra, India.

Parasitic infections such as and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease. Read More

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October 2018
2 Reads

Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti.

PLoS Negl Trop Dis 2018 Nov 29;12(11):e0006992. Epub 2018 Nov 29.

Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

Infections with helminth parasites are controlled by a concerted action of innate and adaptive effector cells in the frame of a type 2 immune response. Basophils are innate effector cells that may also contribute to the initiation and amplification of adaptive immune responses. Here, we use constitutively basophil-deficient Mcpt8-Cre mice to analyze the impact of basophils during initiation and execution of the protective type 2 responses to both, a primary infection and a challenge infection of immune mice with the helminth parasite Strongyloides ratti. Read More

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November 2018
3 Reads

High seroprevalence of Strongyloides stercoralis among individuals from endemic areas considered for solid organ transplant donation: A retrospective serum-bank based study.

PLoS Negl Trop Dis 2018 Nov 29;12(11):e0007010. Epub 2018 Nov 29.

ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.

Background: Strongyloides stercoralis is a worldwide disseminated parasitic disease that can be transmitted from solid organ transplant (SOT) donors to recipients. We determined the serological prevalence of S. stercoralis among deceased individuals from endemic areas considered for SOT donation, using our institution's serum bank. Read More

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November 2018
1 Read

Gastroduodenal involvement in disseminated strongyloidiasis.

JGH Open 2018 Apr 22;2(2):75-76. Epub 2018 Feb 22.

Department of Gastroenterology Kobe City Medical Center General Hospital Kobe Japan.

Here, we report the case of a 57-year-old Peruvian man on long-term corticosteroid therapy for a drug allergy and proton pump inhibitors for chronic dyspepsia symptoms. Upper gastrointestinal endoscopy showed multiple white granular lesions and widespread erosions in the stomach. Our findings indicate that gastric strongyloidiasis should be carefully considered in high-risk patients even if endoscopic findings are nonspecific. Read More

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April 2018
1 Read

Serodiagnosis and early detection of Strongyloides stercoralis infection.

J Microbiol Immunol Infect 2018 Oct 11. Epub 2018 Oct 11.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia. Electronic address:

Strongyloidiasis is a major neglected tropical disease with the potential of causing lifelong infection and mortality. One of the ways for effective control of this disease is developing improved diagnostics, particularly using serological approaches. A serological test can achieve high diagnostic sensitivity and specificity, has the potential for point-of-care translation, and can be used as a screening tool for early detection. Read More

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October 2018
1 Read

Efficacy of ivermectin to control Strongyloides stercoralis infection in sheltered dogs.

Acta Trop 2018 Nov 19;190:204-209. Epub 2018 Nov 19.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy; Dipartimento di Diagnostica e Sanità pubblica, Università degli Studi di Verona, Italy.

In dogs, information on treatments against S. stercoralis infection is rare and anecdotal. The aim of the present work was to evaluate the treatment outcome of S. Read More

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November 2018
10 Reads

Streptococcus pyogenes bacteremia and toxic shock syndrome related to Strongyloides stercoralis hyperinfection: a case report.

J Med Case Rep 2018 Nov 22;12(1):346. Epub 2018 Nov 22.

Reference Parasitology Laboratory, Central Laboratories, Public Health Services, Ministry of Health, Jerusalem, Israel.

Background: We describe a patient with Strongyloides stercoralis hyperinfection associated with Streptococcus pyogenes and with streptococcal toxic shock syndrome. To the best of our knowledge this association has not been previously described.

Case Presentation: A 78 year-old Israeli man, who was born in Iraq but lived in Israel for 66 years, presented with multi-organ failure including acute kidney and hepatic injury, coagulopathy, and lactic acidosis. Read More

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November 2018
10 Reads

Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem.

Am J Trop Med Hyg 2018 Nov 19. Epub 2018 Nov 19.

Division of Neurology, St. Joseph's Health Centre, Toronto, Canada.

Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the CNS sample in one case. Read More

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November 2018
13 Reads

Prevalence of gastrointestinal parasites in bonnet macaque and possible consequences of their unmanaged relocations.

PLoS One 2018 15;13(11):e0207495. Epub 2018 Nov 15.

Department of Conservation Biology, Sálim Ali Centre for Ornithology and Natural History, Coimbatore, Tamil Nadu, India.

Relocation is one of the mitigating measures taken by either local people or related officers to reduce the human-bonnet macaque Macaca radiata conflict in India. The review on relocations of primates in India indicates that monkeys are unscreened for diseases or gastrointestinal parasites (henceforth endoparasites) before relocation. We collected 161 spatial samples from 20 groups of bonnet macaque across their distribution range in south India and 205 temporal samples from a group in Chiksuli in the central Western Ghats. Read More

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November 2018
3 Reads

Fatal strongyloidiasis after corticosteroid therapy for presumed chronic obstructive pulmonary disease.

JMM Case Rep 2018 Sep 11;5(9):e005165. Epub 2018 Sep 11.

Sumeru Hospital, Dhapakhel, Lalitpur, Nepal.

Introduction: Strongyloidiasis is a neglected tropical disease with global prevalence. Under some cases of immune suppression (especially with corticosteroid administration), the nematode involved disseminates, leading to an amplified, possibly lethal hyper-infection syndrome.

Case Presentation: A 56-year-old Nepalese man presenting with chief complaints of nausea, vomiting, joint pain and abdominal cramps was admitted to Sumeru Hospital. Read More

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September 2018
4 Reads

Metabolic consequences of concomitant Strongyloides stercoralis infection in Type 2 diabetes mellitus.

Clin Infect Dis 2018 Nov 8. Epub 2018 Nov 8.

National Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.

Background: Human and animal studies have demonstrated that helminth infections are associated with a decreased prevalence of Type 2 diabetes mellitus (T2DM). However, very little is known about the biochemical and immunological interactions between the two.

Methods: To assess the relationship between a soil-transmitted helminth, Strongyloides stercoralis (Ss) and T2DM, we examined a variety of analytes associated with glycemic control, metabolic processes and T cell driven inflammation at the time of Ss diagnosis and then 6 months after definitive anthelmintic treatment. Read More

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November 2018
3 Reads

Elevated Systemic and Parasite-Antigen Stimulated Levels of Type III IFNs in a Chronic Helminth Infection and Reversal Following Anthelmintic Treatment.

Front Immunol 2018 23;9:2353. Epub 2018 Oct 23.

National Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.

Type III IFNs are important players in immunity to viral and bacterial infections. However, their association with helminth infections has not been examined. To explore the association of Type III IFNs with () infection, we examined the systemic levels of IFN lambda-1, IFN lambda-2 and IFN lambda-3, IL-10, and CXCL10/IP-10 in infected (INF, = 44), helminth-uninfected (UN, = 44) and in post-treatment INF individuals. Read More

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October 2018
3 Reads

Accuracy of Urine and Serum Assays for the Diagnosis of Strongyloidiasis by Three Enzyme-Linked Immunosorbent Assay Protocols.

Am J Trop Med Hyg 2018 Nov 5. Epub 2018 Nov 5.

Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand.

To evaluate the accuracy and reliability of urine assay for the diagnosis of strongyloidiasis, three different immunoassays were used to assess the diagnostic accuracy of anti- IgG in urine and compared with those in serum samples. Analyses by InBios enzyme-linked immunosorbent assay (ELISA) kit (NIE recombinant antigen), SciMedx ELISA kit ( antigen), and our in-house ELISA ( antigen) yielded comparable diagnostic performances between urine and serum assays. Levels of -specific IgG in urine significantly correlated with those in serum. Read More

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November 2018
4 Reads

Terror in the dirt: Sensory determinants of host seeking in soil-transmitted mammalian-parasitic nematodes.

Int J Parasitol Drugs Drug Resist 2018 Dec 26;8(3):496-510. Epub 2018 Oct 26.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA. Electronic address:

Infection with gastrointestinal parasitic nematodes is a major cause of chronic morbidity and economic burden around the world, particularly in low-resource settings. Some parasitic nematode species, including the human-parasitic threadworm Strongyloides stercoralis and human-parasitic hookworms in the genera Ancylostoma and Necator, feature a soil-dwelling infective larval stage that seeks out hosts for infection using a variety of host-emitted sensory cues. Here, we review our current understanding of the behavioral responses of soil-dwelling infective larvae to host-emitted sensory cues, and the molecular and cellular mechanisms that mediate these responses. Read More

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December 2018
4 Reads

Selected aspects of helminth infections Schistosoma sp., Ascaris lumbricoides, Strongyloides stercoralis in individuals diagnosed with human immunodeficiency virus (HIV) infection

Przegl Epidemiol 2018 ;72(3):349-361

University of Warsaw, Faculty of Biology, Department of Parasitology

Co-infections of HIV and other pathogens constitute an important clinical and epidemiological problem. Many studies have played attention to opportunistic co-infections due to the fact that they are used as an indicator for development of AIDS and are present on the all continents. However, in HIV-infected patients helminth infections, which are not aetiologic agents of opportunistic infections, are becoming more and more important. Read More

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January 2018
6 Reads

Severe strongyloidiasis and systemic vasculitis: comorbidity, association or both? Case-based review.

Rheumatol Int 2018 Dec 23;38(12):2315-2321. Epub 2018 Oct 23.

Clinic of Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia.

A possible association between strongyloidiasis and systemic vasculitis is rarely reported in the literature. We report the case of a patient with severe strongyloidiasis and an angiographic finding consistent with polyarteritis nodosa. Diagnosis of strongyloidiasis was made by finding of larvae and adult parasites in samples of the upper gastrointestinal tract mucosa and stool. Read More

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December 2018
8 Reads

A comprehensive analysis of the faecal microbiome and metabolome of Strongyloides stercoralis infected volunteers from a non-endemic area.

Sci Rep 2018 Oct 23;8(1):15651. Epub 2018 Oct 23.

Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.

Data from recent studies support the hypothesis that infections by human gastrointestinal (GI) helminths impact, directly and/or indirectly, on the composition of the host gut microbial flora. However, to the best of our knowledge, these studies have been conducted in helminth-endemic areas with multi-helminth infections and/or in volunteers with underlying gut disorders. Therefore, in this study, we explore the impact of natural mono-infections by the human parasite Strongyloides stercoralis on the faecal microbiota and metabolic profiles of a cohort of human volunteers from a non-endemic area of northern Italy (S+), pre- and post-anthelmintic treatment, and compare the findings with data obtained from a cohort of uninfected controls from the same geographical area (S-). Read More

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October 2018
4 Reads

[Severe infection: a case report].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Sep;30(4):479-480

Department of Laboratory Medicine, Fujian Provincial Hospital, Fuzhou 350001, China.

This paper reports a severe case of infection during routine sputum smear examinations, due to cough and shortness of breath, so as to improve clinicians' awareness of strongyloidiasis to avoid and reduce misdiagnosis and missed diagnosis. Read More

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September 2018
1 Read

Prevalence of enteric parasitic infections among people living with HIV in Abeokuta, Nigeria.

Pan Afr Med J 2018 28;30:66. Epub 2018 May 28.

Department of Medical Microbiology & Parasitology, Ladoke Akintola University of Technology, Osogbo, Nigeria.

Introduction: Enteric parasitic infections have been increasingly recognized as etiology of life-threatening chronic diarrhea in PLWHA in sub-Saharan Africa. This study investigated the prevalence and burden of intestinal parasitic infection among PLWHA in Abeokuta, southwest Nigeria.

Methods: Freshly passed stool samples were collected from PLWHA. Read More

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October 2018
7 Reads

Impact of the health education and preventive equipment package (HEPEP) on prevention of Strongyloides stercoralis infection among rural communities in Northeast Thailand: a cluster randomized controlled trial.

BMC Public Health 2018 Oct 19;18(1):1184. Epub 2018 Oct 19.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Strongyloidiasis is prevalent in northeast Thailand. This study aimed to evaluate the impact of the Health Education and Preventive Equipment Package (HEPEP), a package we developed to improve awareness and aid in the prevention of Strongyloides stercoralis infection among rural communities in northeast Thailand.

Methods: This was an intervention trial conducted in 12 villages (six interventions and six controls) in rural areas of northeast Thailand from March 2016 to September 2017. Read More

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October 2018
2 Reads

Prevalence of Strongyloides stercoralis infection and hyperinfection syndrome among renal allograft recipients in Central Europe.

Sci Rep 2018 Oct 18;8(1):15406. Epub 2018 Oct 18.

Department of Internal Medicine III; Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.

Strongyloides stercoralis is not hyperendemic in European countries but has been increasing in prevalence due to migration and travel. The infection is characterized by a mostly asymptomatic course or nonspecific symptoms in healthy subjects. However, immunosuppression or chemotherapy have been described as leading triggers for Strongyloides stercoralis hyperinfection syndrome and may have a fatal course. Read More

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October 2018
7 Reads

Temperature-dependent behaviors of parasitic helminths.

Neurosci Lett 2018 Nov 15;687:290-303. Epub 2018 Oct 15.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA. Electronic address:

Parasitic helminth infections are the most common source of neglected tropical disease among impoverished global communities. Many helminths infect their hosts via an active, sensory-driven process in which environmentally motile infective larvae position themselves near potential hosts. For these helminths, host seeking and host invasion can be divided into several discrete behaviors that are regulated by both host-emitted and environmental sensory cues, including heat. Read More

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November 2018
6 Reads

Case Report: Subcutaneous Ivermectin Pharmacokinetics in Disseminated Infection: Plasma and Postmortem Analysis.

Am J Trop Med Hyg 2018 Sep 17. Epub 2018 Sep 17.

Pathology Queensland, Brisbane, Australia.

Parenteral ivermectin treatment of disseminated strongyloidiasis and hyperinfection is increasing, although not licensed in humans and with limited pharmacokinetic data available. Plasma and postmortem tissue analysis in an HIV/hepatitis C virus-positive man with disseminated strongyloidiasis suggests loading subcutaneous ivermectin doses are required, from which the central nervous system is protected. Read More

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September 2018
1 Read

Adjunctive dexamethasone for the treatment of HIV-infected adults with tuberculous meningitis (ACT HIV): Study protocol for a randomised controlled trial.

Wellcome Open Res 2018 20;3:31. Epub 2018 Jun 20.

Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.

Tuberculous meningitis (TBM) is the most severe form of tuberculosis. Co-infection with HIV increases the risk of developing TBM, complicates treatment, and substantially worsens outcome. Whether corticosteroids confer a survival benefit in HIV-infected patients with TBM remains uncertain. Read More

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June 2018
2 Reads

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.

Wien Klin Wochenschr 2018 Oct 15;130(19-20):581-588. Epub 2018 Oct 15.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.

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October 2018
2 Reads

An unusual rash: Strongyloides stercoralis presenting as larva currens in a 12-year-old girl with Crohn's disease.

J Paediatr Child Health 2018 Oct 13. Epub 2018 Oct 13.

Alice Springs Hospital, Alice Springs, Northern Territory, Australia.

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October 2018

Knowledge, attitude and practice with respect to soil contamination by Soil-Transmitted Helminths in Ibadan, Southwestern Nigeria.

Parasite Epidemiol Control 2018 Nov 24;3(4):e00075. Epub 2018 Sep 24.

Parasitology Unit, Department of Zoology, Faculty of Science, University of Ibadan, Oyo State, Nigeria.

, , and , the four major Soil-transmitted helminths (STHs) and also infect humans worldwide. Most studies on Soil-transmitted helminths (STHs) carried out in Ibadan were faecal examination based while relatively few soil examination based studies were carried out mostly around school premises using limited number of sampling locations. This study was therefore designed to assess the level of soil contamination with STH and associated risk factors in the eleven local government areas of Ibadan. Read More

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November 2018
2 Reads

Donor-derived strongyloidiasis after organ transplantation in Norway.

Transpl Infect Dis 2018 Oct 8:e13008. Epub 2018 Oct 8.

Regional Advisory Unit for Imported and Tropical Diseases, Department of Infectious Diseases, Oslo University Hospital - Ullevål, Oslo, Norway.

Strongyloides stercoralis is an intestinal helminth which in humans can cause asymptomatic chronic infection maintained for decades through its auto-infective cycle. During solid organ transplantation, recipients may unintentionally receive an organ infected with strongyloides. This is a very rare complication but may have deadly outcome if not detected. Read More

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October 2018
1 Read

Nematode-Infected Mice Acquire Resistance to Subsequent Infection With Unrelated Nematode by Inducing Highly Responsive Group 2 Innate Lymphoid Cells in the Lung.

Front Immunol 2018 19;9:2132. Epub 2018 Sep 19.

Department of Immunology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

The immune responses against helminths have been investigated individually, and it is well-established that infected hosts develop an immunological memory to resist reinfection by the same pathogen. In contrast, it is poorly understood how the host immune system responds to subsequent infection by unrelated parasites after elimination of the first infection. We previously reported that infection of mice with induces the accumulation of group 2 innate lymphoid cells (ILC2s) in the lung. Read More

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September 2018

infection in human and nonhuman primates in selected areas of Oromia Regional State, Ethiopia.

J Vector Borne Dis 2018 Apr-Jun;55(2):116-121

Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Ethiopia.

Background & Objectives: The transmission of schistosomiasis, caused by trematodes of the genus Schistosoma, relies on freshwater snails that act as an intermediate host while human and other mammalian act as the definitive hosts. Many non-human primates (NHPs) such as Chlorocebus aethiops (vervet) and Papio anubis (baboon) are reported to be infected with Schistosoma mansoni in Ethiopia, but the role they play in parasite maintenance and transmission is still not clear. The objective of this study was, therefore, to determine the prevalence of S. Read More

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December 2018
7 Reads

Case Report: Hyperinfection in a Patient with HTLV-1: A Case Report of an Infection with Filariform and Rhabditiform Larvae, Eggs, and Free-Living Adult Females.

Am J Trop Med Hyg 2018 Oct 1. Epub 2018 Oct 1.

Faculdade de Farmácia, Universidade Federal da Bahia (UFBA), Salvador, Brazil.

is the main etiological agent of human strongyloidiasis. Severe strongyloidiasis is commonly associated to alcoholism, corticostereoid use, and human T cell lymphotropic virus type 1 (HTLV-1) coinfection. Herein, we report a case of a 13-year-old boy coinfected with and HTLV-1, excreting several parasitic forms in the stool. Read More

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October 2018
7 Reads

Paediatric Strongyloidiasis in Central Australia.

Trop Med Infect Dis 2018 Jun 13;3(2). Epub 2018 Jun 13.

FRACP, Head of Department, Department of Paediatrics, Alice Springs Hospital, P.O. Box 2234, Alice Springs NT 0871, Australia.

Few published studies are available describing the prevalence of paediatric strongyloidiasis in endemic areas within Australia. This literature review and exploratory clinical audit presents the first seroprevalence data for paediatric patients in Central Australia. A total of 16. Read More

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June 2018
6 Reads

Argument for Inclusion of Strongyloidiasis in the Australian National Notifiable Disease List.

Trop Med Infect Dis 2018 Jun 5;3(2). Epub 2018 Jun 5.

College of Science and Engineering, Flinders University, Bedford Park, SA 5042, Australia.

Strongyloidiasis is an infection caused by the helminth, . Up to 370 million people are infected with the parasite globally, and it has remained endemic in the Indigenous Australian population for many decades. Strongyloidiasis has been also reported in other Australian populations. Read More

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June 2018
2 Reads

The Unique Life Cycle of Strongyloides stercoralis and Implications for Public Health Action.

Trop Med Infect Dis 2018 May 25;3(2). Epub 2018 May 25.

School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, QLD 4700, Australia.

has one of the most complex life cycles of the human-infecting nematodes. A common misconception in medical and public health professions is that in its biology is akin to other intestinal nematodes, such as the hookworms. Despite original evidence provided by medical and veterinary research about this unique helminth, many assumptions have entered the scientific literature. Read More

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May 2018
3 Reads

The Health Effects of Strongyloidiasis on Pregnant Women and Children: A Systematic Literature Review.

Trop Med Infect Dis 2018 May 18;3(2). Epub 2018 May 18.

College of Medicine and Dentistry, James Cook University, Smithfield QLD 4878, Australia.

Strongyloidiasis is a helminth infection that remains under-researched despite its ability to cause significant illness. Women and children may be at particular risk of health consequences from this parasite. This systematic literature review aims to examine research on the long-term health effects that strongyloidiasis has in pregnant women and children. Read More

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May 2018
7 Reads

A Community-Directed Integrated Control Program in Queensland, Australia.

Trop Med Infect Dis 2018 May 4;3(2). Epub 2018 May 4.

College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.

This paper describes two phases of a community-directed intervention to address strongyloidiasis in the remote Aboriginal community of Woorabinda in central Queensland, Australia. The first phase provides the narrative of a community-driven 'treat-and-test' mass drug administration (MDA) intervention that was co-designed by the Community Health Service and the community. The second phase is a description of the re-engagement of the community in order to disseminate the key factors for success in the previous MDA for , as this information was not shared or captured in the first phase. Read More

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May 2018
1 Read

Hyperinfection in an HIV-Infected Patient Successfully Treated with Subcutaneous Ivermectin.

Trop Med Infect Dis 2018 Apr 27;3(2). Epub 2018 Apr 27.

Infectious and Tropical Diseases Unit, Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.

A 39-year-old Ethiopian HIV-positive man with peripheral T-cell lymphoma developed hyperinfection. The patient was initially treated with oral ivermectin for three weeks without response, most likely due to malabsorption because of concomitant paralytic ileus. Given the persistence of larvae in the body fluids, the worsening respiratory status and clinical malabsorption, veterinary parenteral formulation of ivermectin was administered. Read More

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April 2018
1 Read

Application of PCR-Based Tools to Explore Strongyloides Infection in People in Parts of Northern Australia.

Trop Med Infect Dis 2017 Dec 8;2(4). Epub 2017 Dec 8.

School of Health, Medical and Applied Sciences, Central Queensland University, North Rockhampton, QLD 4700, Australia.

Strongyloidiasis, which is caused by infection with the nematode , is endemic to areas of northern Australia. Diagnosis in this region remains difficult due to the distances between endemic communities and diagnostic laboratories, leading to lengthy delays in stool processing for microscopy and culture. PCR represents a viable solution to this difficulty, having potential for high sensitivity detection of , even in older, unpreserved faecal samples. Read More

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December 2017
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A Survey of Intestinal Parasites of Domestic Dogs in Central Queensland.

Trop Med Infect Dis 2017 Nov 21;2(4). Epub 2017 Nov 21.

School of Health, Medical and Applied Sciences, Central Queensland University, North Rockhampton, QSD 4702, Australia.

Australia has a very high rate of dog ownership, which in some circumstances may lead to exposure to zoonotic parasitic diseases from those companion animals. Domestic dog faecal samples ( = 300) were collected from public spaces and private property in the greater Rockhampton (Central Queensland) region and tested for intestinal helminths and protozoa by direct microscopy, two flotation methods and a modified acid-fast stain for cryptosporidia. Intestinal parasites detected included hookworms (25%), complex (9%), (3%), (3%), (1%) and (1%), spp. Read More

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November 2017
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Soil-Transmitted Helminths in Tropical Australia and Asia.

Trop Med Infect Dis 2017 Oct 23;2(4). Epub 2017 Oct 23.

QIMR Berghofer Medical Research Institute, Molecular Parasitology Laboratory, Queensland 4006, Australia.

Soil-transmitted helminths (STH) infect 2 billion people worldwide including significant numbers in South-East Asia (SEA). In Australia, STH are of less concern; however, indigenous communities are endemic for STH, including , as well as for serious clinical infections due to other helminths such as spp. The zoonotic hookworm is also present in Australia and SEA, and may contribute to human infections particularly among pet owners. Read More

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October 2017
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