Curr Opin Chem Biol 2022 May 10;69:102152. Epub 2022 May 10.
The Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, USA; Department of Chemistry, Michigan State University, East Lansing, MI, USA; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA; Department of Chemistry, Northwestern University, Evanston, IL, USA; Elemental Health Institute, Michigan State University, East Lansing, MI, USA. Electronic address:
Faster, more sensitive, and higher resolution quantitative instrumentation are aiding a deeper understanding of how inorganic chemistry regulates key biological processes. Researchers can now image and quantify metals with subcellular resolution, leading to a vast array of new discoveries in organismal development, pathology, and disease. Metals have recently been implicated in several diseases such as Parkinson's, Alzheimers, ischemic stroke, and colorectal cancer that would not be possible without these advancements. Read More