74,492 results match your criteria Stroke Hemorrhagic


Oral anticoagulation in patients with "hemorrhagic-prone" vasculopathies: Overestimated risk?

Neurology 2019 Apr 19. Epub 2019 Apr 19.

From Serviço de Neurologia (L.F.M.), Hospital de Santo António, Centro Hospitalar Universitário do Porto and Instituto de Biologia Molecular e Celular, Instituto de Investigação e Inovação em Saúde Universidade do Porto, Portugal; and Stroke Research Centre (D.W.), University College London and New Zealand Brain Research Institute, Christchurch, New Zealand.

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http://dx.doi.org/10.1212/WNL.0000000000007537DOI Listing

MRI predicts intracranial hemorrhage in patients who receive long-term oral anticoagulation.

Neurology 2019 Apr 19. Epub 2019 Apr 19.

From the Department of Neurology (J.M.-F., L.P.-S., R.M., R.D.-M., A.M.-D., P.C.-R., E.J.-X.) and Epidemiology (I.G.), Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona; Departments of Radiology (S.M.-M.) and Neurology (A.R.-C.), Hospital del Mar-Parc de Salut Mar, Barcelona; Unitat RM IDI (E.M.) and Department of Neurosciences (M.H.-P.), Hospital Germans Trias i Pujol, Badalona; Department of Neurology (M.Z.), Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia, Italy; Department of Neurology (M.G.-C.), Hospital de Sant Joan Despí Moises Broggi, Sant Joan Despí, Spain; Department of Neurology (L. Lara), Hospital de León; Department of Neurology (A.B.), Hospital Universitari Son Espases, Palma de Mallorca; Department of Neurology (A.C.), Hospital de Valladolid; Department of Neurology (A.M.D.A.-B.), Hospital de Donostia; Department of Neurology (Y.B.), Hospital de Burgos; Department of Neurology (B.F.), Hospital Universitario La Paz, Universidad Autónoma de Madrid, Instituto de Investigación IdiPaz, Madrid; Department of Neurology (D. Cánovas), Hospital Parc Taulí, Sabadell; Department of Neurology (L. Llull), Hospital Clínic, Barcelona; Department of Neurology (B.Z.), Hospital de Navarra, Pamplona; Department of Neurology (M.F.), Hospital de Basurto, Bilbao; Department of Neurology (I.C.-N.), Hospital San Pedro de Alcántara, Cáceres; Department of Neurology (J.S.), Hospital Arnau de Vilanova, Lleida; Department of Neurology (D. Cocho), Hospital de Granollers; Department of Neurology (J.K.), F.Ass. Mutua Terrassa; Department of Neurology (E.P.), Hospital de Mataró; Department of Neurology (A.D.F.), Hospital Ramón y Cajal, Madrid; Department of Neurology (M.S.), Hospital La Rioja, Logroño; Department of Neurology (E.Z.-A.), Hospital Virgen del Rocío, Sevilla; Department of Neurology (J.Z.-B.), Hospital Verge de la Cinta, Tortosa; Department of Neurology (I.D.-M.), Hospital de Albacete; Department of Neurology (J.F.-D.), Centro Médico Asturias, Oviedo; Department of Neurology (A.L.), Hospital La Fe, Valencia; Department of Neurology (J.M.), Hospital Virgen de las Nieves, Granada; and Department of Neurology (M.R.-Y.), Hospital Santiago de Compostela, Santiago de Compostela, Spain.

Objective: We tested the hypothesis that the risk of intracranial hemorrhage (ICH) in patients with cardioembolic ischemic stroke who are treated with oral anticoagulants (OAs) can be predicted by evaluating surrogate markers of hemorrhagic-prone cerebral angiopathies using a baseline MRI.

Methods: Patients were participants in a multicenter and prospective observational study. They were older than 64 years, had a recent cardioembolic ischemic stroke, and were new users of OAs. Read More

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http://dx.doi.org/10.1212/WNL.0000000000007532DOI Listing
April 2019
3 Reads

Intracranial Venous Sinus Stenting: A Review of Idiopathic Intracranial Hypertension and Expanding Indications.

Cureus 2019 Feb 4;11(2):e4008. Epub 2019 Feb 4.

Neurosurgery, Penn State Milton Health S. Hershey Medical Center, Hershey, USA.

Idiopathic intracranial hypertension (IIH) is a functionally limiting disorder secondary to increased intracranial pressures (ICPs) with a prevalence of one per 100,000 persons. It is estimated to cost >$400 million per year in productively. Symptoms classically consist of chronic headaches, papilledema, and visual loss. Read More

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http://dx.doi.org/10.7759/cureus.4008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450594PMC
February 2019

Dietary pattern in Adult Patients with Acute Stroke in South India: A Case-Control Study from a Tertiary Care Center in Hyderabad.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):283-293

Department of Neurology, Princess Esra Hospital, Deccan College of Medical Science, Hyderabad, Telangana, India.

Background And Objective: Diet plays a crucial role in the occurrence of stroke. But very few studies have so far been conducted with focus on this aspect of acute stroke in India. The objective of the study was to identify the dietary pattern in patients with acute stroke in South India. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_237_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454960PMC

Is Prevalence of Hypertension Increasing in First-Ever Stroke Patients?: A Hospital-Based Cross-Sectional Study.

Ann Neurosci 2018 Dec 25;25(4):219-222. Epub 2018 Jul 25.

Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Background: Stroke is a devastating and disabling cerebrovascular disease with some amount of residual deficit leading to economic loss. Recent Indian studies have shown a stroke prevalence rate of 471.58/100,000 populations. Read More

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http://dx.doi.org/10.1159/000487066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470354PMC
December 2018

Intractable Medial Anastomotic Branches from the Lenticulostriate Artery Causing Recurrent Hemorrhages in Moyamoya Disease: A Case Report.

World Neurosurg 2019 Apr 14. Epub 2019 Apr 14.

Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Background: While superficial temporal artery (STA) to middle cerebral artery (MCA) anastomosis is a beneficial treatment for hemorrhagic moyamoya disease, indeterminate mechanisms can cause rebleeding even after successful bypass surgery. The authors describe a case with a prominent collateral from the lenticulostriate artery (LSA) causing multiple recurrent hemorrhages after successful STA-MCA anastomosis.

Case: Description: A 49-year-old Japanese woman with moyamoya disease was referred to our institution after suffering intracranial hemorrhage on two occasions. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.066DOI Listing

[Percutaneous left atrial appendage closure in a patient with atrial fibrillation and Rendu-Osler-Weber disease].

G Ital Cardiol (Rome) 2019 Apr;20(4):36-39

U.O. Cardiologia, Azienda Ospedaliera Universitaria di Parma.

Atrial fibrillation is the most common cardiac arrhythmia worldwide and represents a major risk factor for cerebral embolic stroke. The standard therapy in the prevention of stroke is oral anticoagulation therapy (OAT). However, a considerable number of patients are unable to tolerate chronic OAT. Read More

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http://dx.doi.org/10.1714/3146.31277DOI Listing
April 2019
1 Read

The Sub-Saharan Africa Conference on Stroke (SSACS): An idea whose time has come.

J Neurol Sci 2019 May 29;400:194-198. Epub 2019 Mar 29.

Department of Neurology, University of California, San Francisco, USA.

Stroke is a leading cause of global morbidity and mortality. Sub-Saharan Africa (SSA), where an unprecedented rise in stroke burden is currently raging, has the highest age-standardized stroke incidence, stroke prevalence, and stroke mortality rates. This is in sharp contrast to the relative decline in stroke incidence in high-income countries over the past four decades through better awareness and control of vascular risk factors. Read More

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http://dx.doi.org/10.1016/j.jns.2019.03.026DOI Listing

Phantom-based evaluation of near-infrared intracranial hematoma detector performance.

J Biomed Opt 2019 Apr;24(4):1-10

U.S. Food and Drug Administration, Center for Devices and Radiological Health, Silver Spring, Maryla, United States.

Near-infrared spectroscopy (NIRS) is emerging as a rapid, low-cost approach for point-of-care triage of hematomas resulting from traumatic brain injury. However, there remains a lack of standardized test methods for benchtop performance assessment of these devices and incomplete understanding of relevant light-tissue interactions. We propose a phantom-based test method for systems operating near the 800-nm oxy-/deoxy-hemoglobin isosbestic point and implement it to evaluate a clinical system. Read More

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http://dx.doi.org/10.1117/1.JBO.24.4.045001DOI Listing
April 2019
2 Reads

Functional Outcomes After Revascularization Procedures in Patients With Hemorrhagic Moyamoya Disease.

Neurosurgery 2019 Apr 15. Epub 2019 Apr 15.

Department of Neurosurgery and Stan-ford Stroke Center, Stanford University School of Medicine, Stanford, California.

Background: Poor natural history of hemorrhagic Moyamoya disease (MMD) is related to high rehemorrhage rates between 32% and 61%. Postrevascularization, rehemorrhage rates reportedly decrease to 12% to 17%.

Objective: To evaluate long-term functional outcomes and rehemorrhage rates of hemorrhagic MMD patients treated with surgical revascularization and examine these in relation to clinical and radiological factors. Read More

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http://dx.doi.org/10.1093/neuros/nyz074DOI Listing
April 2019
1 Read
3.620 Impact Factor

Disability-Adjusted Life-Years Due to Stroke in Kenya.

Neuroepidemiology 2019 Apr 15:1-7. Epub 2019 Apr 15.

Maine Medical Center Research Institute, Portland, Oregon, USA.

Background: There is little information on stroke morbidity in Kenya to inform health care planning. The disability-adjusted life-years (DALYs) are a time-based measure of health status that incorporates both disability and mortality.

Methods: This was a multicenter prospective study in Kenya's public tertiary hospitals conducted in 2015-2017. Read More

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http://dx.doi.org/10.1159/000498970DOI Listing
April 2019
1 Read
2.558 Impact Factor

Clinical Features of Patients With Spontaneous Intracranial Hypotension Complicated With Bilateral Subdural Fluid Collections.

Headache 2019 Apr 15. Epub 2019 Apr 15.

Department of Neurosurgery, Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.

Background: Subdural hygromas are often found bilaterally in spontaneous intracranial hypotension (SIH). They frequently progress to chronic subdural hematomas (CSDHs), and if the hematomas are formed, it is difficult to consider SIH as an underlying cause. Whether SIH is underlying or not among the patients presenting bilateral subdural fluid collections (hygromas or CSDHs) is clinically important because the treatment strategy should be different between them. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/head.13525
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http://dx.doi.org/10.1111/head.13525DOI Listing
April 2019
2 Reads

Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke.

Front Neurol 2019 29;10:305. Epub 2019 Mar 29.

Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau (IIB Sant Pau), Universitat Autònoma de Barcelona, Barcelona, Spain.

To determine the frequency, risk factors, and impact on the outcome of dehydration after stroke. In this cross-sectional observational study, we included prospectively and consecutively patients with ischemic and hemorrhagic stroke. The serum Urea/Creatinine ratio (U/C) was calculated at admission and 3 days after the stroke. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2019.00305
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http://dx.doi.org/10.3389/fneur.2019.00305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450136PMC
March 2019
2 Reads

Pretreatment Blood Pressure is a Simple Predictor of Hemorrhagic Infarction after Intravenous Recombinant Tissue Plasminogen Activator (rt-PA) Therapy.

J Stroke Cerebrovasc Dis 2019 Apr 11. Epub 2019 Apr 11.

Division of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Fukakusa, Kyoto, Japan.

Background: Hemorrhagic infarction (HI) is among the most severe complications that can occur following the administration of intravenous recombinant tissue plasminogen activator (rt-PA). In the present study, we aimed to determine the optimal cut-off points of blood pressure (BP) for HI after rt-PA treatment, and to compare our findings with those for other prediction models.

Methods: We analyzed data from 109 consecutive patients with stroke treated at our hospital between 2009 and 2016. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.03.035DOI Listing

Hemolysis and Non-Hemorrhagic Stroke during Venoarterial Extracorporeal Membrane Oxygenation.

Ann Thorac Surg 2019 Apr 10. Epub 2019 Apr 10.

Department of Medicine, Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx NY.

Background: Hemolysis, even at low levels, activates platelets to create a prothrombotic state and is common during mechanical circulatory support. We examined the association of low level hemolysis (LLH) and non-hemorrhagic stroke during venoarterial extracorporeal membrane oxygenation (VA ECMO) support.

Methods: A single center retrospective review of all adult patients placed on VA ECMO from January 2012 to September 2017 was conducted. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00034975193051
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http://dx.doi.org/10.1016/j.athoracsur.2019.03.030DOI Listing
April 2019
1 Read

What is the best therapeutic approach to a pediatric patient with a deep-seated brain AVM?

Neurosurg Rev 2019 Apr 13. Epub 2019 Apr 13.

Department of Clinical Neurosciences, Division of Neurosurgery, Geneva University Hospitals, Geneva, Switzerland.

Although brain arteriovenous malformations (bAVMs) account for a very small proportion of cerebral pathologies in the pediatric population, they are the cause of roughly 50% of spontaneous intracranial hemorrhages. Pediatric bAVMs tend to rupture more frequently and seem to have higher recurrence rates than bAVMs in adults. Thus, the management of pediatric bAVMs is particularly challenging. Read More

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http://link.springer.com/10.1007/s10143-019-01101-8
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http://dx.doi.org/10.1007/s10143-019-01101-8DOI Listing
April 2019
6 Reads

Rivaroxaban in cervical and "cervico-cerebral" artery dissections: a new therapeutic option?

Neurol Sci 2019 Apr 12. Epub 2019 Apr 12.

Department of Medicine, Maggiore Hospital, Bologna, BO, Italy.

Antiplatelet agents and vitamin K antagonists (VKA) are usually used in the treatment of cervical (carotid or vertebral) artery dissections (CADs); however, data about the use of direct oral anticoagulants (DOACs) in these conditions are very limited. DOACs have proven to be effective in stroke reduction in non-valvular atrial fibrillation and, when possible, they are preferred to warfarin because of their better safety profile. We describe four cases of CADs and, firstly in literature, cervico-cerebral (CCADs) in young patients (average age of 42 years) treated with rivaroxaban 20 mg daily. Read More

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http://dx.doi.org/10.1007/s10072-019-03882-8DOI Listing
April 2019
2 Reads

Development of bilateral dural arteriovenous fistulae following pial synangiosis for moyamoya syndrome: case report.

J Neurosurg Pediatr 2019 Apr 12:1-5. Epub 2019 Apr 12.

Departments of1Neurosurgery and.

Moyamoya syndrome predisposes patients to ischemic or hemorrhagic stroke due to progressive narrowing of intracranial vessels with subsequent small-vessel collateralization. Dural arteriovenous fistulae (DAVFs) are most commonly noted after venous sinus or cortical vein thrombosis and are believed to be primarily due to venous hypertension and elevated sinus pressures, although there is no known association with moyamoya syndrome, or with surgical treatment for moyamoya disease (MMD). The authors present the case of a 14-year-old girl with Down syndrome treated using pial synangiosis for MMD who subsequently was noted to have bilateral DAVFs. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18603DOI Listing
April 2019
1 Read

Proposal of modification in management strategy for intracranial hemorrhage in low- and middle-income countries.

Clin Neurol Neurosurg 2019 Apr 1;181:21-23. Epub 2019 Apr 1.

Neurosurgery Unit, Department of Surgery, Lagoon Hospitals, Lagos, Nigeria. Electronic address:

This brief communication describes the challenges faced by neurosurgeons in Low- or middle-income countries to treat neurosurgical emergencies from intracranial bleeds (whether traumatic or spontaneous). The authors point out that in low- or middle-income countries and Africa in particular, resources, facilities, and personnel are lacking to follow the guidelines proposed for treating these conditions in high-income countries. The proposal offered here is to move to early surgical intervention because algorithms to monitor patients under conservative management guidelines are often not possible. Read More

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http://dx.doi.org/10.1016/j.clineuro.2019.03.026DOI Listing
April 2019
1 Read
1.248 Impact Factor

Lipid levels and the risk of hemorrhagic stroke among women.

Neurology 2019 Apr 10. Epub 2019 Apr 10.

From the Division of Preventive Medicine, Department of Medicine (P.M. Rist, J.E.B., P.M Ridker), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Department of Neurology (C.S.K.), Emory University, Atlanta, GA; Institute of Public Health (T.K.), Charité-Universitätsmedizin, Berlin, Germany; and Division of Women's Health, Department of Medicine (K.M.R.), Brigham and Women's Hospital, Boston, MA.

Objective: To examine the association between lipid levels and hemorrhagic stroke risk among women.

Methods: We performed a prospective cohort study among 27,937 women enrolled in the Women's Health Study with measured total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), as well as triglycerides. Strokes were confirmed by medical record review. Read More

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http://dx.doi.org/10.1212/WNL.0000000000007454DOI Listing
April 2019
1 Read

Synergistic role of susceptibility-weighted imaging with diffusion-weighted imaging and magnetic resonance angiography in the evaluation of acute arterial stroke.

J Int Med Res 2019 Apr 10:300060519840909. Epub 2019 Apr 10.

3 Department of Internal Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Objective: This study was performed to investigate whether diffusion-weighted imaging (DWI) and susceptibility-weighted imaging (SWI) are more effective than conventional imaging modalities for evaluation of stroke and selection of candidates for thrombolytic therapy.

Methods: Eighty patients who presented within 12 hours of onset of symptoms of brain ischemia underwent 1.5T magnetic resonance imaging. Read More

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http://dx.doi.org/10.1177/0300060519840909DOI Listing
April 2019
1 Read

Acute Management of Ischemic Stroke During Pregnancy.

Obstet Gynecol 2019 Apr 5. Epub 2019 Apr 5.

Departments of Obstetrics & Gynecology and Anesthesiology, the University of Texas Medical Branch at Galveston, Galveston, Texas.

Acute stroke in pregnancy can be devastating. Although neurologists will at some point be involved in the management, most of these patients are likely to first be evaluated by an obstetric care provider. It is, therefore, important for obstetric care providers to have an understanding of the presentation and management of stroke, particularly in the initial period when the window of opportunity for therapy is critical. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003220DOI Listing
April 2019
1 Read

Systemic inflammation in hemorrhagic strokes - A novel neurological sign and therapeutic target?

J Cereb Blood Flow Metab 2019 Apr 8:271678X19841443. Epub 2019 Apr 8.

1 Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Growing evidences suggest that stroke is a systemic disease affecting many organ systems beyond the brain. Stroke-related systemic inflammatory response and immune dysregulations may play an important role in brain injury, recovery, and stroke outcome. The two main phenomena in stroke-related peripheral immune dysregulations are systemic inflammation and post-stroke immunosuppression. Read More

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http://dx.doi.org/10.1177/0271678X19841443DOI Listing
April 2019
1 Read

Hearing loss is associated with increased stroke risk in the Dongfeng-Tongji Cohort.

Atherosclerosis 2019 Mar 18;285:10-16. Epub 2019 Mar 18.

Department of Occupational and Environmental Health and Ministry of Education Key Lab for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

Background And Aims: The evidence concerning the association between hearing loss and stroke is limited. We aimed to investigate the association of hearing loss with risk of stroke and its subtypes among the middle-aged and older Chinese population.

Methods: We included 19,238 participants aged 64. Read More

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.03.012DOI Listing
March 2019
2 Reads
3.994 Impact Factor

Outcomes of fibrinolytic therapy for patients with metastatic cancer and acute pulmonary embolism.

Pulm Pharmacol Ther 2019 Apr 5. Epub 2019 Apr 5.

University of Kentucky Medical Center, Lexington, KY, USA.

Introduction: Malignancy is a common cause of morbidity and mortality in the United States and around the world and the second leading cause of death in the United States. There is little data on the impact of metastatic cancer on the risk of hemorrhagic stroke or mortality among patients undergoing fibrinolytic therapy (FT) for acute PE.

Methods: Using the National Inpatient Sample (NIS) database, we extracted admissions with a primary diagnosis of acute pulmonary embolism that underwent FT from 2010 to 2014. Read More

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http://dx.doi.org/10.1016/j.pupt.2019.04.001DOI Listing
April 2019
2 Reads

Association Between Alcoholic Cirrhosis and Hemorrhagic Stroke: A Nationwide Population-based Study.

Alcohol Alcohol 2019 Apr 8. Epub 2019 Apr 8.

Graduate Institute of Biomedical Sciences and School of Medicine, College of Medicine, China Medical University, Taiwan.

Aims: This study investigated whether patients with alcoholic cirrhosis have a high risk of hemorrhagic stroke.

Methods: In this study, 17,094 patients diagnosed with cirrhosis between 2000 and 2010 were identified using the Taiwan National Health Insurance claims data. Identified patients were randomly selected and propensity score matched with individuals without cirrhosis according to age, sex, comorbidities and index year. Read More

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http://dx.doi.org/10.1093/alcalc/agz025DOI Listing
April 2019
1 Read

Left atrial appendage occlusion in patients older than 85 years. Safety and efficacy in the EWOLUTION registry.

Rev Esp Cardiol (Engl Ed) 2019 Apr 5. Epub 2019 Apr 5.

Cardiologie, St Antonius Hospital, Nieuwegein, The Netherlands.

Introduction And Objectives: Elderly patients with atrial fibrillation are at greater risk of both cardioembolic events and major bleeding than younger patients. Left atrial appendage occlusion (LAAO) could be an attractive alternative for these patients, but there are limited data on outcomes with LAAO in patients ≥ 85 years old. The aim of the present study was to assess the safety and efficacy of LAAO in patients ≥ 85 years old. Read More

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http://dx.doi.org/10.1016/j.rec.2019.02.008DOI Listing
April 2019
1 Read

Outcome of stroke patients on clopidogrel plus proton-pump inhibitors: a single-center cohort study.

Ann Saudi Med 2019 Mar-Apr;39(2):82-86

Background: Recent studies suggest a higher risk of adverse cardiovascular outcome and mortality in patients co-prescribed clopidogrel with proton pump inhibitors (PPI).

Objective: Investigate the impact of concomitant prescription of clopidogrel and PPI on 30-day unplanned readmission and one-year all-cause mortality.

Design: Retrospective longitudinal cohort study. Read More

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http://dx.doi.org/10.5144/02564947.2019.82DOI Listing

Stroke and death risk in ventricular assist device patients varies by ISHLT infection category: An INTERMACS analysis.

J Heart Lung Transplant 2019 Feb 12. Epub 2019 Feb 12.

Department of Heart Failure and Transplantation, Henry Ford Medical Center, Detroit, Michigan, USA.

Background: Ventricular assist device (VAD) patients often experience infections, which increase the risk of stroke and mortality. Using the definitions of the International Society for Heart and Lung Transplantation (ISHLT), we have characterized differences in clinical outcomes for categories of infection: VAD-specific (e.g. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10532498193136
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http://dx.doi.org/10.1016/j.healun.2019.02.006DOI Listing
February 2019
7 Reads

Higher risk of deep vein thrombosis after hemorrhagic stroke than after acute ischemic stroke.

J Vasc Nurs 2019 Mar 21;37(1):18-27. Epub 2019 Jan 21.

Department of Neurology, Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China; Beijing Key Laboratory of Brain Function Restoration, Beijing, China.

Patients with stroke are at particularly increased risk of developing deep vein thrombosis (DVT) during hospitalization. In this study, we aimed to compare the potential risk of in-hospital DVT by stroke subtypes. This study is based on a prospective cohort (in-hospital medical complication after acute stroke [iMCAS] registry) enrolling patients with acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10620303183014
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http://dx.doi.org/10.1016/j.jvn.2018.10.006DOI Listing
March 2019
5 Reads

Highly glycosylated CD147 promotes hemorrhagic transformation after rt-PA treatment in diabetes: a novel therapeutic target?

J Neuroinflammation 2019 Apr 5;16(1):72. Epub 2019 Apr 5.

Department of Neurology, Huashan Hospital, Fudan University, No.12 Middle Wulumuqi Road, Shanghai, 200040, China.

Background: Diabetes is known to be a main risk factor of post-stroke hemorrhagic transformation following recombinant tissue plasminogen activator (rt-PA) therapy. However, the mechanism through which diabetes exacerbates hemorrhagic transformation is insufficiently understood. We aimed to verify that CD147, the extracellular matrix metalloproteinase (MMP) inducer, played a vital role in the progress. Read More

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https://jneuroinflammation.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s12974-019-1460-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449915PMC
April 2019
5 Reads

Safety and Efficacy of Intraventricular Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in Hemorrhagic Stroke Model.

Sci Rep 2019 Apr 5;9(1):5674. Epub 2019 Apr 5.

Department of Laboratory Medicine & Pathology, Mayo Clinic, Jacksonville, Florida, USA.

External ventricular drain (EVD) is used clinically to relieve intracranial pressure and occasionally to deliver medications following intracerebral hemorrhage (ICH). Mesenchymal stem cell (MSC) therapy has been shown to be neuroprotective and can induce neuroregeneration in stroke models. We evaluated the safety and efficacy of delivering MSCs intraventricularly in a rat hemorrhagic stroke model. Read More

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http://dx.doi.org/10.1038/s41598-019-42182-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450980PMC
April 2019
5 Reads

Stroke due to Vasculitis in Children and Adults.

Authors:
David S Younger

Neurol Clin 2019 May;37(2):279-302

Department of Neurology, Division of Neuro-Epidemiology, New York University School of Medicine, New York, NY, USA; School of Public Health, City University of New York, New York, NY, USA. Electronic address:

The vasculitides are diseases characterized by inflammation of blood vessels and inflammatory leukocytes in vessel walls. There is an increased propensity for ischemic stroke, resulting from compromise of vessel lumina with distal tissue ischemia; and hemorrhagic or nonhemorrhagic stroke, and aneurysmal formation and bleeding, due to loss of vessel integrity. Read More

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http://dx.doi.org/10.1016/j.ncl.2019.01.004DOI Listing

Acute ischemic stroke treated with mechanical thrombectomy and fungal endocarditis: A case report and systematic review of the literature.

J Neuroradiol 2019 Apr 2. Epub 2019 Apr 2.

Department of Diagnostic and Interventional Neuroradiology, Foch Hospital, Suresnes, France.

Fungal endocarditis is a rare clinical form of infective endocarditis. The main etiology of FE is Candida albicans but also Candida parapsilosis and the overall mortality is high. We report a case of an acute ischemic stroke treated by mechanical thrombectomy, with the histopathological analysis of the retrieved clot followed by the confirmation of fungal endocarditis. Read More

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http://dx.doi.org/10.1016/j.neurad.2019.03.003DOI Listing
April 2019
4 Reads

Patterns of Recovery From Aphasia in the First 2 Weeks After Stroke.

J Speech Lang Hear Res 2019 Mar;62(3):723-732

Department of Neurology, The University of Arizona, Tucson.

Purpose Recovery from aphasia after stroke has a decelerating trajectory, with the greatest gains taking place early and the slope of change decreasing over time. Despite its importance, little is known regarding evolution of language function in the early postonset period. The goal of this study was to characterize the dynamics and nature of recovery of language function in the acute and early subacute phases of stroke. Read More

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http://pubs.asha.org/doi/10.1044/2018_JSLHR-L-18-0254
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http://dx.doi.org/10.1044/2018_JSLHR-L-18-0254DOI Listing
March 2019
5 Reads

An unusual cause of headache.

BMJ 2019 Apr 4;365:k1933. Epub 2019 Apr 4.

Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, UK.

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http://dx.doi.org/10.1136/bmj.k1933DOI Listing
April 2019
1 Read

Sickle Cell Disease and Stroke.

Pediatr Neurol 2019 Feb 27. Epub 2019 Feb 27.

Developmental Neurosciences Section and Biomedical Research Unit, Clinical and Experimental Sciences, University of Southampton, UCL Great Ormond Street Institute of Child Health, London, UK. Electronic address:

Cerebral infarction is a common complication of sickle cell disease and may manifest as overt stroke or cognitive impairment associated with "silent" cerebral infarction on magnetic resonance imaging. Vasculopathy may be diagnosed on transcranial Doppler or magnetic resonance angiography. The risk factors in sickle cell disease for cognitive impairment, overt ischemic stroke, silent cerebral infarction, overt hemorrhagic stroke, and vasculopathy defined by transcranial Doppler or magnetic resonance angiography overlap, with severe acute and chronic anemia, acute chest crisis, reticulocytosis, and low oxygen saturation reported with the majority. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183130
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http://dx.doi.org/10.1016/j.pediatrneurol.2019.02.018DOI Listing
February 2019
2 Reads

Pattern of intracranial findings detected on magnetic resonance imaging in surviving infants born before 29 weeks of gestation.

PLoS One 2019 4;14(4):e0214683. Epub 2019 Apr 4.

Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States of America.

Despite the positive survival trend in infants born prematurely, the risk for development of intracranial lesions has remained unchanged. However, there are limitations to our understanding of the pattern of the magnetic resonance imaging (MRI) -detected brain pathology in the preterm infants surviving to discharge. The present study outlines the type of intracranial lesions and factors allied with the neonatal brain hemorrhage (NBH) and white matter injury (WMI) seen on MRI at term-equivalent age or close to discharge in infants born before 29 weeks of gestation. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214683PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448872PMC
April 2019
3 Reads

Comparative efficacy and safety of bridging strategies with direct mechanical thrombectomy in large vessel occlusion: A systematic review and meta-analysis.

Medicine (Baltimore) 2019 Apr;98(14):e14956

Department of Neurology, Baotou Central Hospital, Baotou, Inner Mongolia, China.

Background: Whether bridging strategies[intravenous thrombolysis (IVT) + mechanical thrombectomy (MT)] are superior to mechanical thrombectomy alone for large vessel occlusion(LVO) is still uncertain. A systematic review and meta-analysis was conducted to investigate and evaluate comparative efficacy and safety of bridging strategies vs direct MT in patients with LVO.

Methods: The PubMed, EMBASE and Cochrane library databases were searched to evaluate the efficacy and safety of bridging strategies with direct MT in LVO. Read More

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http://dx.doi.org/10.1097/MD.0000000000014956DOI Listing
April 2019
1 Read
5.723 Impact Factor

Third Annual Report From the ISHLT Mechanically Assisted Circulatory Support Registry: A comparison of centrifugal and axial continuous-flow left ventricular assist devices.

J Heart Lung Transplant 2019 Apr;38(4):352-363

University of Alabama at Birmingham, Birmingham, Alabama, USA.

Background: The IMACS Registry compiles and analyzes worldwide data from patients undergoing implantation of durable left ventricular assist devices.

Methods: Data encompassing 16,286 LVAD recipients from 4 collectives and 24 individual hospitals was collected and analyzed. In this 3rd annual report we compare and contrast outcomes, adverse events and risks factors between axial flow and centrifugal flow device recipients. Read More

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http://dx.doi.org/10.1016/j.healun.2019.02.004DOI Listing
April 2019
4 Reads

Is breathing our polluted air a risk factor for stroke?

Authors:
Conrado J Estol

Int J Stroke 2019 Apr 3:1747493019832999. Epub 2019 Apr 3.

Stroke Unit, Sanatorio Guemes, Francisco Acuña de Figueroa 1240, C1180, CABA, Argentina.

The conference "Climate change, air pollution and health" was held at the Pontifical Academy of Sciences. The data presented highlighted that air pollution is a major, under-recognized and modifiable risk factor for stroke and heart disease. Air pollution causes 7. Read More

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http://dx.doi.org/10.1177/1747493019832999DOI Listing
April 2019
1 Read

Psychostimulant Use and Fatal Stroke in Young Adults.

J Forensic Sci 2019 Apr 2. Epub 2019 Apr 2.

National Drug & Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia.

Psychostimulant use is associated with increased stroke risk. To determine the proportion of psychostimulant users among fatal strokes in young adults (15-44 years), all cases were retrieved from the National Coronial Information System (1/1/2009-31/12/2016). A total of 279 cases were identified: hemorrhagic (259), ischemic (8), thrombotic (8), and mycotic (4). Read More

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http://dx.doi.org/10.1111/1556-4029.14056DOI Listing
April 2019
6 Reads

Adherence to recommendations and clinical outcomes of patients hospitalized for stroke: the role of the admission ward-a real-life investigation from Italy.

Neurol Sci 2019 Apr 2. Epub 2019 Apr 2.

National Centre for Healthcare Research & Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy.

Objective: To determine whether out-of-hospital healthcare and adverse outcomes are better in stroke patients admitted to a neurology ward compared with those admitted to general wards.

Methods: Beneficiaries of the National Health Service from the Italian Lombardy Region who were discharged alive after hospital admission during the year 2009 for ischemic stroke (9776 patients) or intracerebral or subarachnoid hemorrhage (1102 patients) entered into the cohort and were followed until 2012. Exposure of interest was the ward type where inpatients were admitted (neuro vs. Read More

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http://link.springer.com/10.1007/s10072-019-03867-7
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http://dx.doi.org/10.1007/s10072-019-03867-7DOI Listing
April 2019
6 Reads

[Management of oral anticoagulation related intracerebral hemorrhage].

Herz 2019 Apr 2. Epub 2019 Apr 2.

Klinik für Neurologie, Universitätsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland.

The incidence of intracerebral hemorrhage (ICH) in patients using oral anticoagulation (OAC) will continue to increase with the demographic change of an aging population. As compared to primary spontaneous ICH, OAC-ICH is characterized by larger hematoma volumes, more frequent hematoma enlargement and intraventricular hemorrhage resulting in an even worse prognosis. Specific treatment should focus on immediate reversal of anticoagulation in addition to the basic acute management of ICH. Read More

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http://link.springer.com/10.1007/s00059-019-4802-y
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http://dx.doi.org/10.1007/s00059-019-4802-yDOI Listing
April 2019
2 Reads

Long-term stroke incidence in proximal thoracic aorta aneurysm survivors.

Int J Stroke 2019 Apr 2:1747493019840944. Epub 2019 Apr 2.

1 Department of Neurology, Buddhist Tzu Chi General Hospital, Hualien.

Background: Aneurysm of proximal thoracic aorta (pTAA) is an often indolent, yet fatal disease. Although advancements in aneurysmal repair techniques have increased long-term survival rates, studies have proven that there are increases in perioperative risk for stroke incidence after pTAA surgery. Conversely, there is little evidence regarding the long-term stroke incidence in pTAA individuals, which strongly influences the morbidity, mortality, and usage of antithrombotic agents. Read More

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http://dx.doi.org/10.1177/1747493019840944DOI Listing
April 2019
3 Reads

Initial experience and one-year follow-up with Neuroform Atlas Stent System for the treatment of brain aneurysms.

Interv Neuroradiol 2019 Apr 2:1591019918819087. Epub 2019 Apr 2.

1 Department of Radiology-Interventional Neuroradiology, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain.

Introduction: The Neuroform Atlas Stent System is a recently introduced modification of the original Neuroform Stent System consisting of a hybrid design with open and closed cells. Initial experience, technical considerations and treatment outcomes including 1-year follow-up using the Atlas stent in combination with coil embolization are reported.

Material And Methods: Thirty patients with 30 unruptured aneurysms were treated with stent reconstruction. Read More

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http://dx.doi.org/10.1177/1591019918819087DOI Listing
April 2019
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Evaluating Real-World Clinical Outcomes in Atrial Fibrillation Patients Receiving the WATCHMAN Left Atrial Appendage Closure Technology.

Circ Arrhythm Electrophysiol 2019 Apr;12(4):e006841

Department of Cardiology, Cardiologicum, Hamburg, Germany (M.W.B.).

Background: Left atrial appendage occlusion with WATCHMAN has emerged as viable alternative to vitamin K antagonists in randomized controlled trials. Evaluating real-life clinical outcomes in atrial fibrillation patients receiving the WATCHMAN left atrial appendage closure technology was designed to collect prospective multicenter outcomes of thromboembolic events, bleeding, and mortality for patients implanted with a WATCHMAN in routine daily practice.

Methods: One thousand twenty patients with a WATCHMAN implant procedure were prospectively followed in 47 centers. Read More

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http://dx.doi.org/10.1161/CIRCEP.118.006841DOI Listing
April 2019
3 Reads

Cerebral Intraparenchymal Hemorrhage: A Review.

JAMA 2019 Apr;321(13):1295-1303

Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Importance: Although spontaneous intraparenchymal hemorrhage (IPH) accounts for less than 20% of cases of stroke, it continues to be associated with the highest mortality of all forms of stroke and substantial morbidity rates.

Observations: Early identification and management of IPH is crucial. Blood pressure control, reversal of associated coagulopathy, care in a dedicated stroke unit, and identification of secondary etiologies are essential to optimizing outcomes. Read More

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http://dx.doi.org/10.1001/jama.2019.2413DOI Listing
April 2019
3 Reads

Intracranial Hemorrhage Caused by Bacterial Meningitis: Case Report and Review of the Literature.

Asian J Neurosurg 2019 Jan-Mar;14(1):234-236

Nishiyama Neurosurgery Hospital, 593-1, Kamo-cho, Sakaide-shi, Kagawa, Japan.

Hemorrhagic stroke is an extremely rare complication in bacterial meningitis. Therefore, the incidence and prognosis have not been fully clarified. In this case report, we describe a case of intracranial hemorrhage caused by bacterial meningitis, which originated from paranasal sinusitis. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_239_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417358PMC
April 2019
3 Reads

Burden of Dengue-related Neurosurgical Emergencies during an Epidemic: A Tertiary Care Experience.

Asian J Neurosurg 2019 Jan-Mar;14(1):211-218

Department of Neurosurgery, Government Medical College, Thiruvananthapuram, Kerala, India.

Dengue is one of the most common flavivirus infections which can manifest from common flu-like fever to fatal hemorrhagic complication. Epidemics of dengue return every year with peaks during the rainfall claiming substantial number of lives in the tropical and subtropical regions of the world. We present manifestations of dengue in patients who underwent neurosurgery in a tertiary referral center during such an epidemic. Read More

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http://www.asianjns.org/text.asp?2019/14/1/211/231060
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http://dx.doi.org/10.4103/ajns.AJNS_318_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417330PMC
April 2019
3 Reads