Search Our Scientific Publications & Authors

Ann Otol Rhinol Laryngol 2021 Apr 23:34894211011453. Epub 2021 Apr 23.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, USA.

Objective: To investigate potential associations between the Predictive Gagging Survey (PGS) with patient experience of gag and discomfort as well as provider perception of patient gag and level of laryngeal visualization during flexible laryngoscopy with stroboscopy (FL-S).

Methods: A total of 53 adult patients undergoing FL-S were recruited for this prospective non-controlled study. PGS was completed before FL-S. Read More

Otolaryngol Head Neck Surg 2021 Apr 20:1945998211008382. Epub 2021 Apr 20.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

Objective: To describe laryngeal findings and voice quality in patients with suspected lung cancer, relative to voice quality and possible laryngeal pathology.

Study Design: Prospective cohort study.

Setting: Tertiary care center. Read More

J Voice 2021 Mar 27. Epub 2021 Mar 27.

Department of Otolaryngology-Head and Neck Surgery, State University of Rio de Janeiro Rio de Janeiro, Rio de Janeiro - RJ, Brazil.

Objective: To determine the prevalence of abnormal laryngeal findings during videostroboscopy in performers presenting to clinic or when having an acute vocal emergency.

Study Design: Retrospective study of professional singers and actors who presented for a vocal evaluation.

Subjects And Methods: A chart review of singers or professional actors who presented in a private otorhinolaryngology clinic between 2014 and 2016. Read More

J Voice 2021 Mar 18. Epub 2021 Mar 18.

Department of Otolaryngology-Head and Neck Surgery, Loma Linda Health University, Loma Linda, California; Department of Otolaryngology-Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania.

Introduction: Improving the voice of patients with vocal atrophy, scar, and sulcus vocalis remains challenging. Platelet-rich plasma (PRP) is an autologous biological suitable for regenerative medicine. Office-based injections of PRP may serve as a source of improved wound healing. Read More

J Voice 2021 Mar 17. Epub 2021 Mar 17.

Otolaryngology Department Pontificia Universidad Católica de Chile. Diagonal Paraguay 362, 7º piso, Edificio Académico, Dpto. Otorrinolaringología, Facultad de Medicina, Pontificia Universidad Católica de Chile. Santiago Centro, Santiago, Chile.

Introduction: Bamboo nodes are transverse creamy-yellow subepithelial nodes in the vocal folds (VF) midpoint, usually bilateral, resembling a bamboo stem. They appear almost exclusively in females, and are associated with underlying autoimmune diseases.

Case Summary: Six female patients, 45. Read More

Laryngoscope 2021 Feb 19. Epub 2021 Feb 19.

The Sean Parker Institute for the Voice, Department of Otolaryngology - Head & Neck Surgery, Weill Cornell Medical College, New York, New York, U.S.A.

Objectives/hypothesis: Performing while on steroids is widely considered to increase risk of vocal injury. This study aims to determine incidence and type of injury, and changes in performers' voices after treatment of vocal fold edema (VFE) with glucocorticoids.

Study Design: Prospective Cohort. Read More

Am J Otolaryngol 2021 May-Jun;42(3):102940. Epub 2021 Jan 28.

Bombay Hospital Voice and Swallowing Centre, Bombay Hospital & Medical Research Centre, Mumbai, Maharashtra, India.

Background: Spasmodic dysphonia (SD) is a neurological condition of the larynx characterised by task specific, involuntary spasms of the intrinsic laryngeal muscles causing frequent voice breaks during speech. The current treatment modality involves Botulinum Toxin injections into the affected group of muscles. This has yielded satisfactory results in Adductor SD (ADSD) and mixed SD but not in Abductor SD (ABSD). Read More

J Synchrotron Radiat 2021 Jan 1;28(Pt 1):146-157. Epub 2021 Jan 1.

Institute for Applied Materials, Karlsruhe Institute of Technology (KIT), PO Box 3640, 76021 Karlsruhe, Germany.

For high-resolution powder diffraction in material science, high photon energies are necessary, especially for in situ and in operando experiments. For this purpose, a multi-analyser detector (MAD) was developed for the high-energy beamline P02.1 at PETRA III of the Deutsches Elektronen-Synchrotron (DESY). Read More

J Voice 2020 Dec 28. Epub 2020 Dec 28.

Centro Hospitalar Universitário do Porto, Instituto de Ciências Biomédicas Abel Salazar - Universidade do Porto, Portugal.

Purpose: To determine cut-off points in auto-assessment questionnaires to predict the presence and extent of presbylarynx signs.

Method: This case control, prospective, observational, and cross-sectional study was carried out on consecutive subjects observed by Otorhinolaryngology, in a tertiary center, in 2020. Each subject underwent fiberoptic videolaryngoscopy with stroboscopy, and presbylarynx was considered when it was identified two or more of the following endoscopic findings: vocal fold bowing, prominence of vocal processes in abduction, and a spindle-shaped glottal gap. Read More

Laryngoscope Investig Otolaryngol 2020 Dec 30;5(6):1117-1124. Epub 2020 Oct 30.

Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and Ear Infirmary Boston Massachusetts USA.

Objective: To describe and visually depict laryngeal complications in patients recovering from coronavirus disease 2019 (COVID-19) infection along with associated patient characteristics.

Study Design: Prospective patient series.

Setting: Tertiary laryngology care centers. Read More

J Voice 2020 Dec 19. Epub 2020 Dec 19.

Department of Otolaryngology - Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania; Otolaryngology and Communication Sciences Research, Lankenau Institute for Medical Research, Pennsylvania. Electronic address:

Laryngopharyngeal reflux (LPR) disease is common. The incidence of newly diagnosed cases has increased substantially due to awareness and development of new diagnostic measurements. The reflux finding score (RFS) and reflux symptom index (RSI) are believed to be useful in the assessment process, including after the initiation of therapy. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(11):40-44

Saint-Petersburg Institute of Ear, Nose, Throat, and Speech, St-Petersburg, Russia.

Objective: To increase the effectiveness of treatment of hypotonic functional dysphonia using physiotherapy in patients with neurovegetative disorders.

Material And Methods: The study included 42 patients, aged from 25 to 64 years, with disturbed vocal function, which included anamnestic analysis, an objective study of ENT organs by conventional methods, a video stroboscopy of the larynx, a cytological study of smears from the laryngeal mucosa, and the determination of the functional state of the autonomic nervous system (ANS).

Results: The clinical-physiological study of VNS shows neurovegetative dysfunction (inadequate autonomic support of activity) in 10 patients. Read More

Adv Otorhinolaryngol 2020 9;85:25-44. Epub 2020 Nov 9.

Department of Otolaryngology Head and Neck Surgery, Icahn School of Medicine, New York, New York, USA,

Videostroboscopy and high-speed imaging is now an accepted way to evaluate laryngeal function in patients with voice disorders. In patients with neurolaryngological diseases such as tremor, laryngeal spasm, and paralysis, having an objective way to evaluate vocal function is desirable. Using digital imaging and analysis, both the videostroboscopy and the high-speed video can be analyzed to obtain relevant measures of vocal function. Read More

J Voice 2020 Oct 1. Epub 2020 Oct 1.

Department of Speech & Language Therapy, University of Ioannina, Ioannina, Greece.

Objective: The inclusion of subjective methods for evaluating Voice Disorders is proven an essential factor for diagnosis as these methods include self-reported questionnaires (eg, Voice Handicap Index-VHI) for everyday clinical practice. In turn, by obtaining cut-off scores of self-perceived questionnaires intended for assessment procedures of different voice disorders (eg, patients with neurological problems), the clinicians might be helped toward finding their patients' needs leading to better monitoring, and treatment suggestions. Consequently, the purpose of this study was to estimate the cut-off scores for the Greek VHI relevant to patients with neurogenic voice disorders. Read More

Am J Otolaryngol 2020 Nov - Dec;41(6):102727. Epub 2020 Sep 13.

Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University, 2-5-1, Shinmachi, Hirakata, Osaka 573-1010, Japan.

Purpose: In cases of unilateral vocal fold paralysis (UVFP), voice disorders caused by glottic insufficiency can lead to a considerable reduction in the patient's quality of life. Voice therapy (VT) is an effective treatment that must be started early after the onset of vocal fold paralysis. This study examined the effect of early VT for patients with UVFP occurring after esophagectomy. Read More

Laryngoscope 2020 Sep 9. Epub 2020 Sep 9.

Department of Otolaryngology-Head and Neck Surgery, Birmingham, Alabama, U.S.A.

Objective/hypothesis: The objective of this study was to investigate the glottic gap area as a significant marker for the severity of presbyphonia as it relates to patient-reported outcome measures (Voice Handicap Index-10 [VHI-10]) and stroboscopic findings.

Study Design: Retrospective case-control study conducted in an academic tertiary voice center.

Methods: Patients seen at a tertiary voice clinic who were diagnosed with presbyphonia without other organic laryngeal pathology from January 2014 to December 2017 were included. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Jun;34(6):528-531

The First Clinical Medical College of Shanxi Medical University，Taiyuan，030001，China.

To study the clinical characteristics and common etiology of vocal cord leukoplakia, and explore the treatment principle. One hundred and fifty-seven patients with vocal cord leukoplakia were recruited in this study. They were assessed by routine laryngoscope, narrow band imaging （NBI）, stroboscope, reflux finding score （RFs） and reflux symptom index （RSI）, and given conservative treatment （smoking cessation, alcohol, acid suppression, sound cessation, etc. Read More

Otolaryngol Head Neck Surg 2021 Mar 11;164(3):631-638. Epub 2020 Aug 11.

Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center, Petach-Tikva, Israel.

Objective: There is a debate regarding the durability of fat implants. Our experience and recent publications suggest fat implantation may deliver a long-lasting improvement. This study aims to present the long-term outcomes for vocal fold fat augmentation using strict harvesting, preparing, and implantation protocols. Read More

Cancers (Basel) 2020 Aug 4;12(8). Epub 2020 Aug 4.

IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.

Background: The endoscopic appearance of glottic erythroleukoplakias is non-predictive of their histopathology, potentially ranging from keratosis to invasive squamous cell carcinoma (SCC). The aim of this study was to assess a comprehensive workup for the one-step diagnosis and treatment of mid-cord erythroleukoplakias, using CO laser excisional biopsy.

Methods: We evaluated 147 untreated patients affected by 155 mid-cord erythroleukoplakias submitted to excisional biopsy by subepithelial (Type I) or subligamental cordectomy (Type II), across two academic institutions. Read More

Laryngoscope 2021 05 4;131(5):1071-1077. Epub 2020 Aug 4.

Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, U.S.A.

Objective: Understanding transgender voice is in nascent stages. This study describes voice characteristics in treatment-seeking trans women by comparing two validated questionnaires-Voice Handicap Index-10 (VHI-10) and Transsexual Voice Questionnaire (TVQ )-and reports incidence of abnormal stroboscopy findings and acoustic characteristics.

Methods: Retrospective review of transgender patients presenting to tertiary-care laryngology center between February 2018-February 2019. Read More

J Voice 2020 Jul 18. Epub 2020 Jul 18.

Department of Otolaryngology - Head & Neck Surgery, Stanford University, Palo Alto, California.

Objectives: Evaluation of trends and utilization of speech-language-pathology (SLP) services, including stroboscopy, before and after medialization laryngoplasty (ML) over 11 years.

Methods: Retrospective national US database study conducted using OptumLabs Data Warehouse. Study cohort included patients (age ≥18 years) who underwent ML between January 2007 and December 2016. Read More

Surgery 2020 10 28;168(4):578-585. Epub 2020 Jun 28.

School of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Otolaryngology Head and Neck Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. Electronic address:

Background: Iatrogenic unilateral vocal fold paralysis caused by thyroid surgery induces profound physical and psychosocial distress in patients. The natural course of functional recovery over time differs substantially across subjects, but the mechanisms underlying this difference remain unclear. In this study, we examined whether the anatomic site of the lesion affected the trajectory of recovery. Read More

Otolaryngol Head Neck Surg 2020 Dec 23;163(6):1240-1243. Epub 2020 Jun 23.

Rush University Medical Center, Chicago, Illinois, USA.

Objective: Type III sulcus is a pathologic structural deformity of the vocal folds that is challenging to accurately diagnose without endoscopic examination under anesthesia. This study aims to further define the clinical presentation and examination features shared among a patient cohort intraoperatively diagnosed with type III sulcus.

Study Design: Case series with chart review. Read More

Ear Nose Throat J 2020 Nov 11;99(9):594-596. Epub 2020 Jun 11.

Department of Otolaryngology Head and Neck Surgery, 147005Bakırköy Teaching and Research Hospital, Istanbul, Turkey.

Am J Otolaryngol 2020 Jul - Aug;41(4):102550. Epub 2020 May 27.

Case Western Reserve University School of Medicine, Cleveland, OH, USA; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA. Electronic address:

Objective: Given high COVID-19 viral load and aerosolization in the head and neck, otolaryngologists are subject to uniquely elevated viral exposure in most of their inpatient and outpatient procedures and interventions. While elective activity has halted across the board nationally, the slow plateau of COVID-19 case rates prompts the question of timing of resumption of clinical activity. We sought to prospectively predict geographical "hot zones" for otolaryngological exposure to COVID-19 based on procedural volumes data from 2013 to 2017. Read More

Ann Otol Rhinol Laryngol 2020 Nov 2;129(11):1063-1070. Epub 2020 Jun 2.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of British Columbia, Vancouver, Canada.

Objectives: To assess voice outcomes using the novel technique of in-office laryngeal electromyography-guided vocal fold injections (LEVFI) with hyaluronic acid to treat glottal insufficiency. Secondary objectives included determining the complication/completion rates and if any factors were associated with improved voice outcomes.

Methods: Retrospective review of patients who received their first LEVFI from August 2017 to December 2018. Read More

HNO 2020 Jun;68(6):461-472

Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinik Ulm, Frauensteige 12, 89075, Ulm, Deutschland.

Unilateral vocal fold palsy is a frequent cause of hoarseness. In the presence of glottis closure insufficiency, the effectiveness of conservative voice therapy is often limited and phonosurgery may be indicated. Injection laryngoplasty is effective for correction of insufficiency. Read More

J Voice 2020 Mar 12. Epub 2020 Mar 12.

Department of Otolaryngology-Head and Neck Surgery, New York State University, New York, New York.

Objective: Smoothed cepstral peak prominence (CPPs) has been shown to be an effective indicator of breathiness (Hillenbrand and Houde, 1996). High-speed videoendoscopy (HSV) is frequently being used as a complement to stroboscopy especially when asymmetric or aperiodic vocal fold vibration is present in dysphonic voices. In an HSV image data set obtained with normal (nondisordered) voice subjects, we have observed that some degree of asymmetry is present in many of the vocal fold displacement curves extracted from the HSV exam videos; therefore, we have used this data set for a pilot study to investigate the relationship of CPPs to cyclical vocal fold vibration parameters, including left-right vocal fold (LVRF) phase asymmetry, in subjects with normal (nondisordered) voices. Read More

Laryngoscope 2020 12 19;130(12):2843-2846. Epub 2020 Feb 19.

Cleveland Clinic, Head and Neck Institute, Cleveland, Ohio.

Objectives/hypothesis: Respiratory laryngeal dystonia (RLD) is poorly understood and rarely reported in the literature. Patients have atypical laryngeal movement resulting in airway obstruction. This motion is neurogenic in nature, is constant while awake, nonepisodic, and non-trigger dependent. Read More