J Cosmet Dermatol 2017 Aug 9. Epub 2017 Aug 9.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Striae distensae (SD) are a frequent skin condition for which treatment remains a challenge. Various laser treatments have been employed to remove the epidermis and cause dermal wound and heating with subsequent dermal collagen remodeling.

Objective: To determine the efficacy and safety of a variable square pulse Erbium: YAG (VSP Er:YAG) laser for the treatment of striae in skin phototypes III-IV. Read More

J Cosmet Dermatol 2017 Jul 29. Epub 2017 Jul 29.

Department of Dermatology, Huadong Hospital, Fudan University, Shanghai, China.

Background: Striae distensae (SD) are a common dermatologic problem that plagues many people. Although there are many therapeutic modalities have been used to treat SD, effective method has been disappointing for striae Alba.

Aims: To evaluate the clinical and histopathologic efficacy and safety of the 2940-nm erbium yttrium aluminum garnet (Er:YAG) ablative fractional laser (AFL) with recombinant bovine basic fibroblast growth factor (rb-bFGF) and light-emitting diode-red light (LED-RL) for the treatment of striae alba. Read More

J Plast Reconstr Aesthet Surg 2017 Jun 17. Epub 2017 Jun 17.

Department of Plastic and Reconstructive Surgery - Burn Center, University Hospital of Ghent, De Pintelaan 185, 9000 Ghent, Belgium.

Background: Patients who suffer from scars or wrinkles have several therapeutic options to improve the appearance of their skin. The available treatment modalities that provide desirable results are often overtly invasive and entail a risk of undesirable adverse effects. Microneedling has recently emerged as a non-ablative alternative for treating patients who are concerned with the aesthetic changes that result from injury, disease or ageing. Read More

J Cosmet Laser Ther 2017 Jun 30:1-5. Epub 2017 Jun 30.

a Department of Dermatology , Koc University School of Medicine , Istanbul , Turkey.

Background: Striae distensae (SD) are a type of dermal scarring that is quite common and difficult to treat. Two forms are known: striae rubrae (SR) and striae albae (SA).

Objective: We compared the long-term clinical effectiveness of a 1550-nm non-ablative fractional laser (NAFL) in treating SR and SA. Read More

J Cosmet Laser Ther 2017 Jun 30:1-6. Epub 2017 Jun 30.

a Department of Dermatology and Cutaneous Biology Research Center, International St. Mary's Hospital , Catholic Kwandong University, College of Medicine , Incheon , Republic of Korea.

Background: Needleless transcutaneous pneumatic injections (TPIs) are a minimally invasive way to deliver the solution into the skin for therapeutic purposes. The suggested action mechanisms of TPI therapy include mechanical stimulation, immediate tissue shrinkage and late wound healing.

Methods: Thirteen Korean patients were treated with TPI for atrophic skin disorders, including acne scars, striae albae, post-furuncle, or carbuncle scars, and horizontal wrinkles with lipoatrophy. Read More

Int J Womens Dermatol 2017 Jun 6;3(2):77-85. Epub 2016 Dec 6.

Department of Dermatology, Palo Alto Foundation Medical Group, Mountain View, CA.

Background: Striae gravidarum (SG) are atrophic linear scars that represent one of the most common connective tissue changes during pregnancy. SG can cause emotional and psychological distress for many women. Research on risk factors, prevention, and management of SG has been often inconclusive. Read More

J Am Acad Dermatol 2017 Sep 24;77(3):559-568.e18. Epub 2017 May 24.

Centre for Dermatological Research, University of Manchester, Manchester, United Kingdom. Electronic address:

Background: Striae distensae are permanent dermal lesions that can cause significant psychosocial distress. A detailed understanding of the numerous treatment modalities available is essential to ensuring optimal patient outcomes.

Objective: Our objective was to evaluate and summarize the different treatment methods for striae distensae by linking their proposed modes of action with the histopathogenesis of the condition to guide patient treatment. Read More

Dermatol Surg 2017 May;43(5):649-650

Surgical & Aesthetic Dermatology, Sacramento, California.

Dermatol Surg 2017 May;43(5):635-648

*Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania; †Dermatology Service, Sacramento VA Medical Center, Mather, California; ‡Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, New York; §Department of Internal Medicine, California Pacific Medical Center, San Francisco, California; ¶Department of Dermatology, UC Davis Medical Center, Sacramento, California.

Background: Striae distensae (SD) are aesthetically troublesome to patients and therapeutically challenging.

Objective: Herein, the authors comprehensively review the literature pertaining to the history, pathogenesis, clinical presentation, clinical rating scales, and laboratory, imaging, and histologic features of SD.

Methods And Materials: A review of PubMed, MEDLINE, Scopus, Embase, and Google scholar was conducted, including literature published from 1773 to August 6, 2016. Read More

J Cosmet Dermatol 2017 Apr 4. Epub 2017 Apr 4.

Department of Histology, Ain Shams University, Cairo, Egypt.

Background: Striae distensae (SD), a type of dermal scarring, are psychologically disappointing. To date, information and scientific research behind the role of hormonal factors in the development of SD are still unclear. It is vital to understand striae to offer patients the best therapeutic options. Read More

Dermatol Online J 2017 Mar 15;23(3). Epub 2017 Mar 15.

University of Texas Medical Branch at Galveston, Texas,.

We report a 12-year-old girl with new diagnosisof right knee Osgood-Schlatter who developedhorizontal purple striae below the right tibial tubercletwo months after a right knee intra-articular steroidinjection. She is the second reported case of unilaterallocalized striae after an intra-articular steroid injectionand the first with triamcinalone as the corticosteroid. Read More

Drug Des Devel Ther 2017 24;11:521-531. Epub 2017 Feb 24.

Department of Dermatopharmacy and Cosmetics.

Striae distensae are a frequent skin condition associated with pregnancy, weight change or lack of skin elasticity. The aim of this research was to obtain a topical product containing herbal active ingredients with documented antioxidant and anti-inflammatory activity (Punica granatum seed oil and Croton lechleri resin extract) and demonstrate its positive effect on prevention and treatment of striae distensae. First, the cream base formulation was optimized through experimental design. Read More

Lasers Surg Med 2017 Aug 20;49(6):563-569. Epub 2017 Feb 20.

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, P. R. China.

Background: Laser and other energy devices are emerging, minimally invasive treatments for scars. Among the various techniques, fractional microplasma radiofrequency technology (FMRT) has proven to be an effective treatment option for various types of scars and skin conditions such as rhytids, striae distensae, and hyperpigmentation.

Objective: This prospective clinical trial was designed to evaluate the efficacy and safety of FMRT for treating non-hypertrophic post-burn scars in the Asian population. Read More

BMJ Case Rep 2017 Feb 16;2017. Epub 2017 Feb 16.

Department of Pathology, Jordan University of Science and Technology, Irbid, Jordan.

JAAD Case Rep 2017 Jan 31;3(1):39-41. Epub 2017 Jan 31.

University of Utah, Department of Dermatology, Salt Lake City, Utah; Laboratory for Investigative Dermatology, Rockefeller University, New York, New York.

Int J Dermatol 2017 Feb 2;56(2):e37-e38. Epub 2016 Nov 2.

Department ofDermatology, Complejo Hospitalario Universitario, University of Santiago de Compostela, Santiago de Compostela, Spain.

J Cosmet Dermatol 2017 Mar 21;16(1):84-90. Epub 2016 Oct 21.

Skin Center, Srinakharinwirot University, Wattana, Bangkok, Thailand.

Background: Striae distensae (SD) is a form of dermal scar. A number of treatments have been proposed, but they usually have unsatisfactory result especially in striae alba. Recently, nanofractional RF has been developed. Read More

Indian J Dermatol 2016 Sep-Oct;61(5):565-6

Department of Psychiatry, University of Foggia, Foggia, Italy.

Clin Cosmet Investig Dermatol 2016 6;9:249-55. Epub 2016 Sep 6.

Department of Histology, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hațieganu", Cluj-Napoca, Romania.

Purpose: Striae distensae represent the result of the failure of the dermis to sustain intrinsic mechanical forces. Intensive moisturization of the lesions and use of emollient oils have been recommended for the prevention and treatment of striae distensae rubra. The aim of this research was to formulate an emollient water-in-oil cosmetic cream containing argan oil, which may be helpful in the prevention or early treatment of striae distensae. Read More

Lasers Med Sci 2016 Dec 5;31(9):1845-1853. Epub 2016 Sep 5.

Department of Dermatology, NILES, Cairo, Egypt.

Striae distensae are common undesirable skin lesions of significant aesthetic concern. To compare the efficacy of two fluences (75 and 100 J/cm(2)) of long-pulsed Nd:YAG laser in the treatment of striae. Forty-five patients (Fitzpatrick skin types III-V) aged between 11 and 36 years with striae (23 patients with rubra type and 22 with alba type) were enrolled in the study. Read More

Plast Reconstr Surg 2016 Sep;138(3 Suppl):165S-78S

Columbus, Ohio; and Dallas, Texas From the Department of Plastic Surgery, the Ohio State University Wexner Medical Center; and Department of Plastic Surgery, the University of Texas-Southwestern Medical Center.

Background: Scars represent the visible sequelae of trauma, injury, burn, or surgery. They may induce distress in the patient because of their aesthetically unpleasant appearance, especially if they are excessively raised, depressed, wide, or erythematous. They may also cause the patient symptoms of pain, tightness, and pruritus. Read More

Postgrad Med J 2017 Feb 5;93(1096):108. Epub 2016 Aug 5.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

J Cosmet Dermatol 2016 Dec 29;15(4):503-513. Epub 2016 Jun 29.

Department of Dermatology, Faculty of Medicine, Minia University, Al-Minya, Egypt.

Background: Microdermabrasion is a nonchemical superficial resurfacing procedure that removes the stratum corneum. Because it is a somewhat subtle procedure, it may be difficult to demonstrate its cosmetic benefit.

Objectives: To assess the efficacy of microdermabrasion in treatment of melasma, postacne scarring, striae distensae, and photoaging by a series of microdermabrasion sittings through clinical, histometric, and histopathologic analysis. Read More

J Cosmet Dermatol 2016 Dec 20;15(4):565. Epub 2016 Jun 20.

Plastic Surgery Department, Henri Mondor Hospital, Creteil, France.

The article entitled "Comparison between the efficacy and safety of platelet-rich plasma vs microdermabrasion in the treatment of striae distensae: clinical and histopathological study" (Zeinab Abd El-Samad Ibrahim, et al.) is very interesting but the methodology is not robust. Our mains comments concerned the count of the cells, the activation of the PRP and the method of assessment. Read More

Clin Dermatol 2016 May-Jun;34(3):314-9. Epub 2016 Feb 9.

Department of Dermatology, University of California School of Medicine, San Francisco, California; Department of Dermatology, Palo Alto Foundation Medical Group, Mountain View, California. Electronic address:

The most recent reclassification of dermatoses of pregnancy includes polymorphic eruption of pregnancy, atopic eruption of pregnancy, and pemphigoid gestationis; intrahepatic cholestasis of pregnancy, strictly not a dermatosis, was included in specific dermatoses of pregnancy for working purposes. Another dermatosis, pustular psoriasis of pregnancy, could be included for similar reasons. The nomenclature of these pregnancy-specific eruptions has been revised several times, generating potential confusion among practitioners. Read More

Dermatol Surg 2016 May;42 Suppl 2:S124-30

*New Orleans, Louisiana; †Adjunct Clinical Faculty, Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Florida.

Background: Combination therapies are becoming more popular as a multifaceted approach to treating common aesthetic conditions.

Objective: Often, the use of multiple techniques and modalities can lead to improved outcomes; however, there is a lack of current evidence on the use of combination therapies in the literature.

Methods And Materials: With the recent expansion of minimally and noninvasive options for treatment of the outer thigh and buttock, it is important to understand how these techniques can be used together while avoiding increased risk. Read More

J Cosmet Dermatol 2016 Dec 19;15(4):393-398. Epub 2016 Apr 19.

Laboratório de Pesquisa em Biofísica Celular e Inflamação, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.

Background: Striae distensae are linear atrophic dermal scars with associated epidermal atrophy. This recurrent skin disorder causes a significant cosmetic and psychologic concern and remains a therapeutic challenge, especially when they are mature and hypopigmented (striae alba).

Aims: In this prospective single-center study, we evaluated the efficacy, safety, and patient's satisfaction of galvanopuncture for the treatment of striae alba. Read More

J Cosmet Laser Ther 2016 Oct 2;18(6):330-4. Epub 2016 Jun 2.

a Departments of Dermatology , Venereology and Andrology, Faculty of Human Medicine , Zagazig University, Zagazig , Egypt.

Unlabelled: Striae distensae (SD) is a challenging cosmetic problem for which various treatment modalities have been applied. Our aim was to evaluate the efficacy and tolerability of needling therapy versus microdermabrasion with sonophoresis in the treatment of SD.

Materials And Methods: Forty female patients with SD (mean duration 2. Read More

Indian J Dermatol 2016 Mar-Apr;61(2):239

Department of Dermatology, PSG Institute of Medical Sciences and Research, Peelamedu, Coimbatore, Tamil Nadu, India. E-mail:

Indian J Dermatol 2016 Mar-Apr;61(2):174-80

Department of Public Health and Community Medicine, Faculty of Medicine, Assiut University, Asyut, Egypt.

Context: Striae distensae are linear atrophic dermal scars covered with flat atrophic epidermis. They may cause disfigurement, especially in females. Many factors may cause striae distensae such as steroids, obesity, and pregnancy. Read More

J Chin Med Assoc 2016 May 4;79(5):272-5. Epub 2016 Apr 4.

Department of Obstetrics and Gynecology, Zekai Tahir Burak Women's Healthcare Training and Research Hospital, Ankara, Turkey.

Background: Striae gravidarum (SG), commonly called stretch marks, is an important cosmetic problem which is not treatable, although preventive measures might be effective. The aim of this study was to determine individual risk factors causing SG and the degree to which preventive measures could be effective.

Methods: This prospective observational study included 211 singleton primiparous pregnant women who were hospitalized for birth and who did not have systemic diseases or other risk factors, like drug use or polyhydramnios. Read More

Aust Fam Physician 2016 Apr;45(4):206-7

FRACP, is Senior Staff Specialist, Endocrinology and Obstetric Medicine, Mater Hospital, Brisbane, Queensland.

Lasers Surg Med 2016 Mar 12;48(3):245-53. Epub 2016 Jan 12.

Department of Dermatology, University Hospital of Nice, Nice, France.

Background And Objective: Very few treatments for striae are based on prospective randomized trials. The objective of this study was to assess the efficacy of bipolar fractional radiofrequency and bipolar radiofrequency potentiated with infrared light, alone or combined, for treating abdominal stretch marks.

Study Design/materials And Methods: Bicentric prospective interventional randomized controlled trial in the department of Dermatology of University Hospital of Nice and Aesthetics Laser Center of Bordeaux, France. Read More

Am J Clin Dermatol 2016 Jun;17(3):239-56

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Suite 2175, Miami, FL, 33136, USA.

Striae distensae (SD) are common dermatologic lesions that often arise as a result of rapid weight change, certain endocrine conditions, or prolonged exposure to steroids. SD initially present as raised edematous plaques (striae rubra), after which they become white and atrophic (striae alba) owing to local breakdown and reorganization of collagen and elastin. There currently exists no reliable treatment option, though numerous topical applications have been attempted. Read More

J Cosmet Laser Ther 2016 28;18(2):75-9. Epub 2016 Jan 28.

b Department of Histology , Faculty of Medicine, Zagazig University , Zagazig , Egypt.

Background And Objectives: Striae are atrophic dermal scars with overlying epidermal atrophy causing cosmetic concern. This study assesses and compares the efficacy and safety of needling therapy versus CO2 fractional laser in treatment of striae.

Methods: Twenty Egyptian female patients with striae in the abdomen and lower limbs were involved in the study. Read More

Dermatol Surg 2016 Feb;42(2):225-31

Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.

Background: Aesthetically, striae distensae (SD) are a source of great concern. No treatment modality is currently considered the gold standard. However, studies of nonablative fractionated lasers (NAFLs) have been promising. Read More

Br J Dermatol 2015 Dec;173(6):1359-60

Centre for Dermatology Research, Faculty of Medicine & Human Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, U.K..

Dermatol Res Pract 2015 9;2015:640482. Epub 2015 Nov 9.

Graduate Program in Medicine and Health Sciences, School of Medicine, PUCRS (FAMED), Avenida Ipiranga 6681, 90619-900 Porto Alegre, RS, Brazil.

Vitamin D (VD) plays a role in the skin regulation. Striae Distensae (SD) are manifestations of epidermal atrophy that occurs after tissue tearing due to overstretching or rapid growth. The objective of this study was to investigate the relation between serum VD and occurrence of SD in women who had undergone mammaplasty with silicone implants. Read More

J Drugs Dermatol 2015 Nov;14(11):1205-8

Objective: To evaluate the efficacy of a fractional ablative micro-plasma radiofrequency (RF) device in the reduction of the appearance of abdominal striae.

Methods: Five female patients (age range, 30-60) with abdomen striae alba (n=4) and striae rubra (n=1) were enrolled in the study. Skin type distribution among the 5 patients was two type II, one type III, and two type IVs. Read More

J Eur Acad Dermatol Venereol 2016 Feb 20;30(2):211-22. Epub 2015 Oct 20.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, UK.

Striae distensae (SD) are common dermal lesions, with significant physical and psychological impact. Many therapeutic modalities are available but none can completely eradicate SD. The most common therapy is the application of topicals used both therapeutically and prophylactically. Read More

Cardiol Young 2016 Apr 7;26(4):796-8. Epub 2015 Oct 7.

Steven and Alexandra Cohen Children's Medical Center - North Shore-LIJ Health System,Division of Pediatric Cardiology,New Hyde Park,New York,United States of America.

Fetal constriction of the ductus arteriosus is a complication of maternal non-steroidal anti-inflammatory drug use and polyphenol-rich food intake. It is unclear as to whether polyphenol-containing topical treatments have similar effects. We present a case of fetal constriction of the ductus arteriosus, severe right ventricular hypertension, and a right ventricular aneurysm associated with maternal use of a topical treatment for striae gravidarum. Read More

J Am Acad Dermatol 2015 Oct;73(4):699-700

Department of Dermatology, Rouen University Hospital, INSERM U 905, University of Rouen, Rouen, France. Electronic address:

Hautarzt 2015 Oct;66(10):753-6

Dermatologische Gemeinschaftspraxis, Pasinger Bahnhofsplatz1, 81241, München, Deutschland.

Nonablative photothermolysis has become an established technique in laser dermatology. It is mainly used for restructuring dermal connective tissue in order to treat, for example, acne scars or solar elastosis. It is also applied to the treatment of melasma and other benign cutaneous pigment disorders. Read More

Hautarzt 2015 Oct;66(10):748-52

, Bonn, Deutschland.

Background: Medical skin needling as a nonablative procedure appears to be a good alternative to conventional surgical treatment options for the treatment of acne scars and striae.

Objective: The effect of medical skin needling particularly with regard to the treatment of acne scars and striae as an alternative to ablative therapy options is explained.

Materials And Methods: A summary of recent publications on medical skin needling in terms of skin regeneration in vivo and improving skin quality of patients in vivo in striae is provided. Read More

J Cosmet Dermatol 2015 Dec 23;14(4):315-23. Epub 2015 Jul 23.

Department of Dermatology, University of California, Davis, Sacramento, CA, USA.

Platelet-rich plasma (PRP) is a highly concentrated autologous solution of plasma prepared from a patient's own blood. PRP contains platelets that are purported to release numerous growth factors that may be valuable in numerous dermatologic applications. Here, we review systematically the clinical cosmetic applications of PRP including: androgenetic alopecia, scar revision, acne scars, skin rejuvenation, dermal augmentation, and striae distensae to understand the potential and best practices for PRP use. Read More

Br J Dermatol 2015 Dec 8;173(6):1420-30. Epub 2015 Nov 8.

Department of Dermatology, University of Michigan Medical School, 1910 Taubman Center, 1500 East Medical Center Drive, Ann Arbor, MI, 48109, U.S.A.

Background: Striae gravidarum (SG), or 'stretch marks' of pregnancy, begin as erythematous streaks, and mature over months to years to become permanent scar-like bands that may be hypopigmented, atrophic and lax.

Objectives: To investigate early molecular alterations that may promote laxity of mature SG, we investigated the dermal elastic fibre network, which provides human skin with elastic properties.

Methods: We obtained skin samples of newly developed, erythematous abdominal SG in healthy pregnant women. Read More

Eur J Endocrinol 2015 Oct 8;173(4):M33-8. Epub 2015 Jul 8.

The Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institutes of Health, Building 10, CRC, 1 East, Rm 1-3140, 10 Center Dr, MSC 1109, Bethesda, Maryland 20892-1109, USA

Endogenous pathologic hypercortisolism, or Cushing's syndrome, is associated with poor quality of life, morbidity, and increased mortality. Early diagnosis may mitigate against this natural history of the disorder. The clinical presentation of Cushing's syndrome varies, in part related to the extent and duration of cortisol excess. Read More

J Cosmet Dermatol 2015 Dec 6;14(4):336-46. Epub 2015 Jul 6.

Faculty of Medicine, Department of Pathology, Tanta University, Tanta, Egypt.

Striae distensae is a challenging cosmetic problem for which various treatment modalities have been applied. To compare between the efficacy and tolerability of intradermal injection of autologous platelet-rich plasma (PRP) vs. microdermabrasion in the treatment of striae distensae. Read More

Plast Reconstr Surg 2015 Jul;136(1):121e-122e

University of California, San Diego, San Diego, Calif.