J Cosmet Dermatol 2018 Jun 19. Epub 2018 Jun 19.

Pathology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.

Background: Striae distensae are very common cutaneous disorders that produce great psychological stress for women.

Objective: measure and compare between efficacy and tolerability of three modalities for treatment of striae distensae.

Patients And Methods: Forty-five female patients with striae distensae were randomly selected from the outpatient dermatology clinics of Al-Zahra university Hospital within 6 months period. Read More

J Am Acad Dermatol 2018 Jun 8. Epub 2018 Jun 8.

Senior Resident, Sanjay Gandhi Memorial Hospital, New Delh.

Acta Dermatovenerol Croat 2018 Apr;26(1):61-63

Benigno Monteagudo-Sánchez, MD, Hospital Arquitecto Marcide, Avenida Residencia SN , 15405 Ferrol (A Coruńa), A Coruńa, Spain;

Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). Read More

Dermatol Surg 2018 May;44(5):697-704

All authors are affiliated with the Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Background: Striae distensae (SD) are dermal scars associated with atrophy of the epidermis.

Objective: To evaluate the effect and safety of intralesional injection of platelet-rich plasma (PRP) versus topical tretinoin 0.05% in treatment of SD. Read More

Br J Dermatol 2018 Apr;178(4):e278

Department of Dermatology and Allergy, Technical University of Munich, Biedersteiner Straße 29, 80802, Munich, Germany.

J Cosmet Laser Ther 2018 Mar 16:1-5. Epub 2018 Mar 16.

c Doctor , Post-Graduate Program in Rehabilitation Sciences - UNIFAL-MG , Alfenas , Minas Gerais , Brazil.

Objective: To assess the effects of galvano-puncture (GG) and dermabrasion (DG) in reducing striae distensae in the gluteal region of women.

Methods: This randomized, controlled, single-blind clinical trial was conducted at the UNIFAL-MG. Participants were 48 female who had striae distensae alba in the gluteal region. Read More

J Cosmet Dermatol 2018 Mar 1. Epub 2018 Mar 1.

Plastic, Reconstructive and Aesthetic Surgery Clinic, Institute of Surgery, Medical University of Lodz, Łódź, Poland.

Background: Striae have been reported to be one of the most common skin lesions and a commonly encountered esthetic problem.

Objectives: The aim of this research was to examine elastin gene polymorphism (rs7787362, ELN) and collagen type III alpha 1 polymorphism (rs1800255, COL3A1) among polish woman population with SD in comparison with women without the lesions and to verify these polymorphisms as risk factors for SD.

Methods: Seventy female students (35 with striae (the mean age 23. Read More

J Cosmet Laser Ther 2018 Feb 16:1-9. Epub 2018 Feb 16.

b Dermatological Surgery & Laser Unit, St John's Institute of Dermatology, Guy's Hospital Cancer Centre , Guy's and St Thomas' NHS Foundation Trust , London , UK.

Striae distensae (SD), otherwise known as "stretchmarks," are a common presenting complaint, particularly in young healthy women. SD are hypothesized to form in a patient when the cross-linked collagen is "overstretched" and rupture of this collagen matrix causes the striae. Thus, many treatments work by increasing collagen synthesis. Read More

J Cosmet Dermatol 2018 Jan 7. Epub 2018 Jan 7.

Pathology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

Background: Striae distensae are dermal scars with a linear atrophic depression. The exact origin of striae distensae remains unrevealed, but low expression of collagen and fibronectin genes in the affected tissue was found. Several treatment modalities have been proposed, yet no consistent modality is available. Read More

Lasers Med Sci 2018 Apr 7;33(3):609-617. Epub 2018 Jan 7.

Biomedical Engineering Innovation Center, Biomedical Vibrational Spectroscopy Group, Universidade Brasil-UNBr, Rua Carolina Fonseca, 235-08230-030, Itaquera, Sao Paulo, Brazil.

This research work mainly deals with studying qualitatively the changes in the dermal collagen of two forms of striae distensae (SD) namely striae rubrae (SR) and striae albae (SA) when compared to normal skin (NS) using confocal Raman spectroscopy. The methodology includes an in vivo human skin study for the comparison of confocal Raman spectra of dermis region of SR, SA, and NS by supervised multivariate analysis using partial least squares discriminant analysis (PLS-DA) to determine qualitatively the changes in dermal collagen. These groups are further analyzed for the extent of hydration of dermal collagen by studying the changes in the water content bound to it. Read More

J Am Acad Dermatol 2017 Dec 22. Epub 2017 Dec 22.

Department of Physiological Sciences, Santa Casa de Sao Paulo School of Medical Sciences.

J Cosmet Dermatol 2017 Dec 6. Epub 2017 Dec 6.

Chair of Cosmetology, Faculty of Pharmacy, Department of Cosmetology and Aesthetic Dermatology, Medical University of Łódź, Łódź, Poland.

Objective: The aim of the study was to evaluate the effectiveness of carboxytherapy in the treatment of striae distensae. Additionally, discomfort and side effects associated with the treatment were assessed.

Materials And Methods: This study involved 15 women aged 22-40 years. Read More

Pediatr Dermatol 2018 Jan 21;35(1):59-63. Epub 2017 Nov 21.

Department of Dermatology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Background: This study examines the clinical characteristics and demographics of teenage boys with horizontal striae distensae of the lower back in an outpatient setting.

Methods: Retrospective medical chart reviews and telephone survey studies were completed on an outpatient cohort of 12 boys 11 to 17 years of age with a clinical diagnosis of transverse striae distensae of the lower back at a single-center, university-based, pediatric dermatology practice. We evaluated the clinical features of the striae, participant demographic characteristics, and past medical history. Read More

Dermatol Surg 2017 Nov 14. Epub 2017 Nov 14.

Pinnacle Dermatology, Joliet, Illinois Dermatology Section, Edward Hines Jr. VA Hospital, Hines, Illinois Department of Dermatology, Mayo Clinic, Rochester, Minnesota Division of Dermatology, Loyola University, Maywood, Illinois.

J Cosmet Dermatol 2017 Nov 6. Epub 2017 Nov 6.

Plastic, Reconstructive and Aesthetic Surgery Clinic, Institute of Surgery, Medical University of Lodz, Lodz, Poland.

Background: Striae have been reported to be one of the most common skin changes and a commonly encountered esthetic problem.

Objectives: To analyze risk factors of striae not associated with pregnancy and verify if body build and composition influence striae distensae (SD) occurrence and visibility.

Methods: Eighty female students (40 with striae (the mean age 23. Read More

Lasers Med Sci 2018 Jan 4;33(1):75-78. Epub 2017 Oct 4.

I.C.L.I.D, Milan, Italy.

The efficacy of NAFL in the treatment of striae distensae (SD) has been demonstrated. Nevertheless, the base for this improvement has not been clarified yet. The aim of this study is to describe in vivo variations occurring in the skin after the treatment, using reflectance confocal microscopy (RCM). Read More

Ann Dermatol 2017 Oct 25;29(5):633-634. Epub 2017 Aug 25.

Department of Dermatology, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.

Ecancermedicalscience 2017 7;11:756. Epub 2017 Aug 7.

Department of Pediatric Hematology and Oncology, AP-HM, Boulevard Jean Moulin, 13005, Marseille France.

Glioblastoma cerebri is a rare paediatric malignancy with dismal prognosis [Chappé C, Riffaud L, and Tréguier C (2013) 565-571 https://doi.org/10.1007/s00381-012-2016-1 PMID: 23306961] and no established standard of care. Read More

Midwifery 2017 Nov 1;54:25-28. Epub 2017 Aug 1.

Henrietta Szold/Hadassah-Hebrew University School of Nursing, Faculty of Medicine, Jerusalem, Israel.

Objectives: to examine the association between the severities of Striae Gravidarum (SG) and Obstetric Anal Sphincter Injuries (OASIS) and to measure the symptoms regarding urinary incontinence, fecal/flatus incontinence, and dyspareunia, at 6 and 12 months postpartum.

Design: this is a cohort study.

Setting: four university teaching medical centers in Israel, two in the north and two in the center of the country. Read More

J Cosmet Dermatol 2017 Dec 9;16(4):466-470. Epub 2017 Aug 9.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Striae distensae (SD) are a frequent skin condition for which treatment remains a challenge. Various laser treatments have been employed to remove the epidermis and cause dermal wound and heating with subsequent dermal collagen remodeling.

Objective: To determine the efficacy and safety of a variable square pulse Erbium: YAG (VSP Er:YAG) laser for the treatment of striae in skin phototypes III-IV. Read More

J Cosmet Dermatol 2018 Apr 29;17(2):176-183. Epub 2017 Jul 29.

Department of Dermatology, Huadong Hospital, Fudan University, Shanghai, China.

Background: Striae distensae (SD) are a common dermatologic problem that plagues many people. Although there are many therapeutic modalities have been used to treat SD, effective method has been disappointing for striae Alba.

Aims: To evaluate the clinical and histopathologic efficacy and safety of the 2940-nm erbium yttrium aluminum garnet (Er:YAG) ablative fractional laser (AFL) with recombinant bovine basic fibroblast growth factor (rb-bFGF) and light-emitting diode-red light (LED-RL) for the treatment of striae alba. Read More

CMAJ 2017 07;189(28):E942

Department of Medicine (Jogova, Hwang), University of Toronto; Centre for Urban Health Solutions (Hwang), St. Michael's Hospital, Toronto, Ont.

J Plast Reconstr Aesthet Surg 2018 Jan 17;71(1):1-14. Epub 2017 Jun 17.

Department of Plastic and Reconstructive Surgery - Burn Center, University Hospital of Ghent, De Pintelaan 185, 9000 Ghent, Belgium.

Background: Patients who suffer from scars or wrinkles have several therapeutic options to improve the appearance of their skin. The available treatment modalities that provide desirable results are often overtly invasive and entail a risk of undesirable adverse effects. Microneedling has recently emerged as a non-ablative alternative for treating patients who are concerned with the aesthetic changes that result from injury, disease or ageing. Read More

J Cosmet Laser Ther 2017 Nov 30;19(7):378-382. Epub 2017 Jun 30.

a Department of Dermatology , Koc University School of Medicine , Istanbul , Turkey.

Background: Striae distensae (SD) are a type of dermal scarring that is quite common and difficult to treat. Two forms are known: striae rubrae (SR) and striae albae (SA).

Objective: We compared the long-term clinical effectiveness of a 1550-nm non-ablative fractional laser (NAFL) in treating SR and SA. Read More

J Cosmet Laser Ther 2017 Dec 30;19(8):479-484. Epub 2017 Jun 30.

a Department of Dermatology and Cutaneous Biology Research Center, International St. Mary's Hospital , Catholic Kwandong University, College of Medicine , Incheon , Republic of Korea.

Background: Needleless transcutaneous pneumatic injections (TPIs) are a minimally invasive way to deliver the solution into the skin for therapeutic purposes. The suggested action mechanisms of TPI therapy include mechanical stimulation, immediate tissue shrinkage and late wound healing.

Methods: Thirteen Korean patients were treated with TPI for atrophic skin disorders, including acne scars, striae albae, post-furuncle, or carbuncle scars, and horizontal wrinkles with lipoatrophy. Read More

Endocr Pract 2017 Aug 14;23(8):962-970. Epub 2017 Jun 14.

Objective: Cushing disease (CD) results from excessive exposure to glucocorticoids caused by an adrenocorticotropic hormone-secreting pituitary tumor. Inadequately treated CD is associated with significant morbidity and elevated mortality. Multicenter data on CD patients treated in routine clinical practice are needed to assess treatment outcomes in this rare disorder. Read More

Int J Womens Dermatol 2017 Jun 6;3(2):77-85. Epub 2016 Dec 6.

Department of Dermatology, Palo Alto Foundation Medical Group, Mountain View, CA.

Background: Striae gravidarum (SG) are atrophic linear scars that represent one of the most common connective tissue changes during pregnancy. SG can cause emotional and psychological distress for many women. Research on risk factors, prevention, and management of SG has been often inconclusive. Read More

J Am Acad Dermatol 2017 Sep 24;77(3):559-568.e18. Epub 2017 May 24.

Centre for Dermatological Research, University of Manchester, Manchester, United Kingdom. Electronic address:

Background: Striae distensae are permanent dermal lesions that can cause significant psychosocial distress. A detailed understanding of the numerous treatment modalities available is essential to ensuring optimal patient outcomes.

Objective: Our objective was to evaluate and summarize the different treatment methods for striae distensae by linking their proposed modes of action with the histopathogenesis of the condition to guide patient treatment. Read More

Dermatol Surg 2017 05;43(5):649-650

Surgical & Aesthetic Dermatology, Sacramento, California.

Dermatol Surg 2017 May;43(5):635-648

*Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania; †Dermatology Service, Sacramento VA Medical Center, Mather, California; ‡Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, New York; §Department of Internal Medicine, California Pacific Medical Center, San Francisco, California; ¶Department of Dermatology, UC Davis Medical Center, Sacramento, California.

Background: Striae distensae (SD) are aesthetically troublesome to patients and therapeutically challenging.

Objective: Herein, the authors comprehensively review the literature pertaining to the history, pathogenesis, clinical presentation, clinical rating scales, and laboratory, imaging, and histologic features of SD.

Methods And Materials: A review of PubMed, MEDLINE, Scopus, Embase, and Google scholar was conducted, including literature published from 1773 to August 6, 2016. Read More

J Cosmet Dermatol 2017 Jun 4;16(2):279-286. Epub 2017 Apr 4.

Department of Histology, Ain Shams University, Cairo, Egypt.

Background: Striae distensae (SD), a type of dermal scarring, are psychologically disappointing. To date, information and scientific research behind the role of hormonal factors in the development of SD are still unclear. It is vital to understand striae to offer patients the best therapeutic options. Read More

BMJ Open 2017 04 3;7(4):e014603. Epub 2017 Apr 3.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, School of Biological Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

Objectives: To identify the side effects most important to glucocorticoid (GC) users through a survey of a UK online health community (Healthunlocked.com).

Design: Online cross-sectional survey. Read More

Dermatol Online J 2017 Mar 15;23(3). Epub 2017 Mar 15.

University of Texas Medical Branch at Galveston, Texas,.

We report a 12-year-old girl with new diagnosisof right knee Osgood-Schlatter who developedhorizontal purple striae below the right tibial tubercletwo months after a right knee intra-articular steroidinjection. She is the second reported case of unilaterallocalized striae after an intra-articular steroid injectionand the first with triamcinalone as the corticosteroid. Read More

Drug Des Devel Ther 2017 24;11:521-531. Epub 2017 Feb 24.

Department of Dermatopharmacy and Cosmetics.

Striae distensae are a frequent skin condition associated with pregnancy, weight change or lack of skin elasticity. The aim of this research was to obtain a topical product containing herbal active ingredients with documented antioxidant and anti-inflammatory activity ( seed oil and resin extract) and demonstrate its positive effect on prevention and treatment of striae distensae. First, the cream base formulation was optimized through experimental design. Read More

Lasers Surg Med 2017 Aug 20;49(6):563-569. Epub 2017 Feb 20.

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, P. R. China.

Background: Laser and other energy devices are emerging, minimally invasive treatments for scars. Among the various techniques, fractional microplasma radiofrequency technology (FMRT) has proven to be an effective treatment option for various types of scars and skin conditions such as rhytids, striae distensae, and hyperpigmentation.

Objective: This prospective clinical trial was designed to evaluate the efficacy and safety of FMRT for treating non-hypertrophic post-burn scars in the Asian population. Read More

BMJ Case Rep 2017 Feb 16;2017. Epub 2017 Feb 16.

Department of Pathology, Jordan University of Science and Technology, Irbid, Jordan.

JAAD Case Rep 2017 Jan 31;3(1):39-41. Epub 2017 Jan 31.

University of Utah, Department of Dermatology, Salt Lake City, Utah; Laboratory for Investigative Dermatology, Rockefeller University, New York, New York.

Int J Dermatol 2017 Feb 2;56(2):e37-e38. Epub 2016 Nov 2.

Department ofDermatology, Complejo Hospitalario Universitario, University of Santiago de Compostela, Santiago de Compostela, Spain.

J Cosmet Dermatol 2017 Mar 21;16(1):84-90. Epub 2016 Oct 21.

Skin Center, Srinakharinwirot University, Wattana, Bangkok, Thailand.

Background: Striae distensae (SD) is a form of dermal scar. A number of treatments have been proposed, but they usually have unsatisfactory result especially in striae alba. Recently, nanofractional RF has been developed. Read More

Indian J Dermatol 2016 Sep-Oct;61(5):565-6

Department of Psychiatry, University of Foggia, Foggia, Italy.

Clin Cosmet Investig Dermatol 2016 6;9:249-55. Epub 2016 Sep 6.

Department of Histology, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hațieganu", Cluj-Napoca, Romania.

Purpose: Striae distensae represent the result of the failure of the dermis to sustain intrinsic mechanical forces. Intensive moisturization of the lesions and use of emollient oils have been recommended for the prevention and treatment of striae distensae rubra. The aim of this research was to formulate an emollient water-in-oil cosmetic cream containing argan oil, which may be helpful in the prevention or early treatment of striae distensae. Read More

J Cosmet Dermatol 2017 Sep 7;16(3):416-420. Epub 2016 Sep 7.

Department of Obstetrics, Medical Faculty, KSU, Maternal-Foetal Medicine Unit, Kahramanmaras, Turkey.

Objective: Striae gravidarum is a form of scarring on the skin observed during pregnancy and can cause serious cosmetic problems. Striae gravidarum may be influenced by hormonal changes, although the etiology is not clear. The aim of this study was to investigate whether body mass index (BMI) and serum collagenase-2 levels in pregnant women are related to the development of striae gravidarum. Read More

Lasers Med Sci 2016 Dec 5;31(9):1845-1853. Epub 2016 Sep 5.

Department of Dermatology, NILES, Cairo, Egypt.

Striae distensae are common undesirable skin lesions of significant aesthetic concern. To compare the efficacy of two fluences (75 and 100 J/cm) of long-pulsed Nd:YAG laser in the treatment of striae. Forty-five patients (Fitzpatrick skin types III-V) aged between 11 and 36 years with striae (23 patients with rubra type and 22 with alba type) were enrolled in the study. Read More

Plast Reconstr Surg 2016 Sep;138(3 Suppl):165S-78S

Columbus, Ohio; and Dallas, Texas From the Department of Plastic Surgery, the Ohio State University Wexner Medical Center; and Department of Plastic Surgery, the University of Texas-Southwestern Medical Center.

Background: Scars represent the visible sequelae of trauma, injury, burn, or surgery. They may induce distress in the patient because of their aesthetically unpleasant appearance, especially if they are excessively raised, depressed, wide, or erythematous. They may also cause the patient symptoms of pain, tightness, and pruritus. Read More

Postgrad Med J 2017 Feb 5;93(1096):108. Epub 2016 Aug 5.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

J Cosmet Dermatol 2016 Dec 29;15(4):503-513. Epub 2016 Jun 29.

Department of Dermatology, Faculty of Medicine, Minia University, Al-Minya, Egypt.

Background: Microdermabrasion is a nonchemical superficial resurfacing procedure that removes the stratum corneum. Because it is a somewhat subtle procedure, it may be difficult to demonstrate its cosmetic benefit.

Objectives: To assess the efficacy of microdermabrasion in treatment of melasma, postacne scarring, striae distensae, and photoaging by a series of microdermabrasion sittings through clinical, histometric, and histopathologic analysis. Read More

J Cosmet Dermatol 2016 Dec 20;15(4):565. Epub 2016 Jun 20.

Plastic Surgery Department, Henri Mondor Hospital, Creteil, France.

The article entitled "Comparison between the efficacy and safety of platelet-rich plasma vs microdermabrasion in the treatment of striae distensae: clinical and histopathological study" (Zeinab Abd El-Samad Ibrahim, et al.) is very interesting but the methodology is not robust. Our mains comments concerned the count of the cells, the activation of the PRP and the method of assessment. Read More

Clin Dermatol 2016 May-Jun;34(3):314-9. Epub 2016 Feb 9.

Department of Dermatology, University of California School of Medicine, San Francisco, California; Department of Dermatology, Palo Alto Foundation Medical Group, Mountain View, California. Electronic address:

The most recent reclassification of dermatoses of pregnancy includes polymorphic eruption of pregnancy, atopic eruption of pregnancy, and pemphigoid gestationis; intrahepatic cholestasis of pregnancy, strictly not a dermatosis, was included in specific dermatoses of pregnancy for working purposes. Another dermatosis, pustular psoriasis of pregnancy, could be included for similar reasons. The nomenclature of these pregnancy-specific eruptions has been revised several times, generating potential confusion among practitioners. Read More

Dermatol Surg 2016 May;42 Suppl 2:S124-30

*New Orleans, Louisiana; †Adjunct Clinical Faculty, Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Florida.

Background: Combination therapies are becoming more popular as a multifaceted approach to treating common aesthetic conditions.

Objective: Often, the use of multiple techniques and modalities can lead to improved outcomes; however, there is a lack of current evidence on the use of combination therapies in the literature.

Methods And Materials: With the recent expansion of minimally and noninvasive options for treatment of the outer thigh and buttock, it is important to understand how these techniques can be used together while avoiding increased risk. Read More