Search Our Scientific Publications & Authors

J Biomech 2022 Jun 11;141:111192. Epub 2022 Jun 11.

Injury Biomechanics and Aging Laboratory, Department of Kinesiology and Health Sciences, University of Waterloo, 200 University Ave West, Waterloo, Ontario N2L 3G1 Canada; Schlegel-UW Research Institute for Aging, 250 Laurelwood Drive, Waterloo, Ontario N2J 0E2 Canada. Electronic address:

Metrics of femur geometry and body composition have been linked to clinical hip fracture risk. Mechanistic explanations for these relationships have generally focused on femur strength; however, impact loading also modulates fracture risk. We evaluated the potential effects of femur geometry and body composition on femoral neck stresses during lateral impacts. Read More

JBMR Plus 2022 Jun 5;6(6):e10627. Epub 2022 May 5.

Department of Electrical and Computer Engineering University of Iowa Iowa City IA USA.

Osteoporosis causes bone fragility and elevates fracture risk. Applications of finite element (FE) analysis (FEA) for assessment of trabecular bone (Tb) microstructural strength at whole-body computed tomography (CT) imaging are limited due to challenges with Tb microstructural segmentation. We present a nonlinear FEA method for distal tibia CT scans evading binary segmentation of Tb microstructure, while accounting for bone microstructural distribution. Read More

Semin Vasc Surg 2022 Jun 26;35(2):180-189. Epub 2022 Apr 26.

University of Kentucky College of Medicine, 800 Rose Street, MN 275, Lexington, KY 40536. Electronic address:

In an aging population with a rising incidence of peripheral artery disease, endovascular therapy is a favorable alternative to open surgical bypass. As a minimally invasive approach, endovascular therapy incurs less physiologic stress and periprocedural complications. Balloon angioplasty and stenting have been the predominant tools in peripheral endovascular therapy. Read More

Contrast Media Mol Imaging 2022 18;2022:2079098. Epub 2022 May 18.

Department of Thoracic Surgery, Shanghai Pudong Hospital Fudan University Pudong Medical Center, Shanghai 201399, China.

Objective: A case-control study was conducted, to assess the complications, short-term effectiveness, and quality of life of video-assisted thoracoscopic surgery with conventional surgery in the treatment of rib fractures.

Methods: From February 2018 to April 2021, 100 patients with rib fractures who required surgical treatment at the hospital were selected. Patients were randomly divided into control and study groups. Read More

BMC Musculoskelet Disord 2022 Jun 2;23(1):525. Epub 2022 Jun 2.

Department of Orthopaedics, Qilu Hospital of Shandong University, No.107 Wenhua West Road, Jinan, 250012, Shandong Province, China.

Objectives: The humerus fracture is one of the most commonly occurring fractures. In this research, we attempted to evaluate and compare the extent of malrotation and biomechanical environment after surgical treatment of humeral shaft fractures.

Methods: A finite element (FE) model of the shoulder was built based on Computed Tomography (CT) data of a patient with a humeral shaft fracture. Read More

BMJ Case Rep 2022 Jun 1;15(6). Epub 2022 Jun 1.

Trauma & Orthopaedics, University College London Hospitals NHS Foundation Trust, London, UK.

Vertical stress fractures of the patella are rare, with only a handful of bilateral cases reported. Stress fractures in the athletic community are often due to repetitive strain and submaximal loading, with minimal recovery time. An Olympic marathon runner in her 30s presented with right anterolateral knee pain. Read More

Adv Sci (Weinh) 2022 May 29:e2200700. Epub 2022 May 29.

Department of Physics and Shenzhen Key Laboratory of Advanced Quantum Functional Materials and Devices, Southern University of Science and Technology, Shenzhen, 518055, China.

Monolayer transition-metal dichalcogenides, e.g., MoS , typically have high intrinsic strength and Young's modulus, but low fracture toughness. Read More

Bull Hosp Jt Dis (2013) 2022 Jun;80(2):165-167

Isolated fractures of the trapezoid are an exceedingly rare injury, and stress fractures of the carpus are similarly uncommon. An 18-year-old competitive baseball player presented with atraumatic, progressive hand pain. He was found to have a stress fracture of the trapezoid. Read More

Bull Hosp Jt Dis (2013) 2022 06;80(2):160-164

Med Eng Phys 2022 06 25;104:103810. Epub 2022 Apr 25.

Department of Mechanical Engineering, Indian Institute of Technology Ropar, Rupnagar 140001, Punjab, India. Electronic address:

Type 2 diabetes (T2D) is a well-known disease that impaired bone mechanical properties and increases the risk of fragility fracture. The bone tissue is a viscoelastic material that means the loading rate determines its mechanical properties. This study investigates the impact of T2D on the viscoelastic properties of human bone and its association with microstructure and biochemical properties. Read More

BMC Musculoskelet Disord 2022 May 27;23(1):500. Epub 2022 May 27.

National Clinical Research Center for Orthopaedics, Sports Medicine & Rehabilitation, Beijing, China.

Background: Osteochondral lesion of the talus (OLT) is one of the most common ankle injuries, which will lead to biomechanical changes in the ankle joint and ultimately affect ankle function. Finite element analysis (FEA) is used to clarify the effect of talus osteochondral defects on the stability of the ankle joint at different depths. However, no research has been conducted on talus osteochondral defect areas that require prompt intervention. Read More

J Athl Train 2022 May 27. Epub 2022 May 27.

University of California - Davis Health, Sacramento, California, United States.

Isolated first rib stress fractures in athletes are thought to be rare. In this case series, three Division I athletes developed isolated first rib stress fractures over the span of one year, revealing that these may occur more often than previously understood. These fractures can be easily missed because of low incidence, lack of clinical suspicion, and vague presentation. Read More

Equine Vet J 2022 May 26. Epub 2022 May 26.

Comparative Orthopaedic Research Laboratory, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Quebec, Canada.

Background: Focal bone microcracks with osteoclast recruitment and bone lysis, may reduce fracture resistance in racehorses. As current imaging does not detect all horses at risk for fracture, the discovery of novel serum biomarkers of bone resorption or osteoclast activity could potentially address this unmet clinical need. The biology of equine osteoclasts on their natural substrate, equine bone, has never been studied in vitro and may permit identification of specific biomarkers of their activity. Read More

Bone 2022 Aug 16;161:116443. Epub 2022 May 16.

Biomedical Engineering Graduate Program, 2500 University Drive NW, University of Calgary, Calgary, AB T2N 1N4, Canada; Human Performance Laboratory, Faculty of Kinesiology, 2500 University Drive NW, University of Calgary, Calgary, AB T2N 1N4, Canada; McCaig Institute for Bone and Joint Health, 3280 Hospital Dr NW, University of Calgary, Calgary, AB T2N 4Z6, Canada. Electronic address:

Tibial stress fracture is a common injury in runners and military personnel. Elevated bone strain is believed to be associated with the development of stress fractures and is influenced by bone geometry and density. The purpose of this study was to characterize tibial-fibular geometry and density variations in young active adults, and to quantify the influence of these variations on finite element-predicted bone strain. Read More

Radiol Case Rep 2022 Jul 9;17(7):2432-2436. Epub 2022 May 9.

Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, USA.

Accessory articulation between the transverse processes of the C6 and C7 vertebrae is an extremely rare anatomic variant that has only been previously described in two instances. In this report, we present the case of a 25-year-old male who sustained numerous injuries associated with a physical assault. A CT study of the cervical spine revealed a linear lucency mimicking a fracture but found on closer inspection to represent an accessory articulation between the anterior tubercles of the right transverse processes of the C6 and C7 vertebrae. Read More

BMC Womens Health 2022 05 13;22(1):166. Epub 2022 May 13.

Department of Medical Imaging, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, People's Republic of China.

Background: To determine the incidence, clinical and MRI features of sacral insufficiency fracture (SIF) after radiotherapy (RT) in patients with cervical cancer.

Methods: Our study included 167 patients with cervical cancer after radiotherapy that underwent pelvic MRI for follow-up. MRIs included pre-enhanced T1-weighted, coronal fat-Suppressed T2-weighted (FS-T2W) and enhanced T1-weighted imaging. Read More

Acta Med Okayama 2022 Apr;76(2):121-127

Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

Bone marrow edema (BME) after meniscus injury and risk factors for subchondral insufficiency fracture of the knee (SIFK) have been reported. However, their association with medial meniscus posterior root tear (MMPRT) remains unknown. We investigated the association of BME volume (BME-V), posterior shinycorner lesion (PSCL), and SIFK with MMPRT to examine the correlations between BME-V and medial meniscus extrusion (MME), PSCL and duration from injury to the time of magnetic resonance imaging (duration), and SIFK and duration. Read More

Case Rep Orthop 2022 20;2022:6507577. Epub 2022 Apr 20.

Orthopaedic Department, Lausanne University Hospital, Lausanne, Switzerland.

Avulsion injuries of the LCL most commonly occur at the fibular insertion. Femoral LCL avulsion injuries have only been previously described in pediatric patients or as multiligament knee injury components among adults. This case series with comprehensive literature review describes for the first time 2 cases of isolated LCL femoral avulsion fractures in adults including conservative treatment outcomes. Read More

J Chiropr Med 2021 Dec 6;20(4):218-223. Epub 2022 Apr 6.

Radiology Department, Logan University, Chesterfield, Missouri.

Objective: The purpose of this report is to describe the clinical, radiographic, and diagnostic ultrasound findings in a patient who sustained a type III Salter-Harris fracture of the first proximal phalanx.

Clinical Features: A 14-year-old male baseball player presented to a chiropractic clinic with a 2-day history of proximal thumb pain, which began following a forceful hyperabduction injury while sliding into base. Thenar swelling was evident on clinical examination, and both active and passive thumb motions were painful in all directions. Read More

J Tradit Complement Med 2022 May 3;12(3):225-234. Epub 2021 Aug 3.

Department of Biotechnology, Faculty of Applied Science UCSI University, No. 1, Jalan Menara Gading, UCSI Heights, (Taman Connaught) Cheras, 56000, Kuala Lumpur, Malaysia.

Spirulina (blue-green algae) contains a wide range of nutrients with medicinal properties which include β-carotene, chromium, and moderate amounts of vitamins B. This study aims to determine the preventive effect of spirulina against bone fragility linked to type 2 diabetes mellitus. Thirty Sprague-Dawley rats were divided into five groups (n = 6) and diabetes was induced using streptozocin. Read More

Injury 2022 Jun 22;53(6):1815-1823. Epub 2022 Apr 22.

Department of Mechanical Engineering, Ferdowsi University of Mashhad, Mashhad, Iran; Institute of Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland. Electronic address:

Introduction: In the early stage of fracture fixation, the aim of a unilateral external fixator (UEF) to stimulate healing and maintain stability may be suppressed by using inadequate number of pins. Cortical thinning due to age or osteoporosis endangers a successful fracture fixation.

Materials And Methods: This study evaluates the initial strength and stability of the fracture fixation and tissue differentiation under the influences of variable cortical thickness (5 mm to 1 mm) and variable number of pins (1 to 4 in each bone fragment). Read More

Injury 2022 Jun 26;53(6):1805-1814. Epub 2022 Apr 26.

Institut Pprime UPR 3346, CNRS - Université de Poitiers - ISAE-ENSMA, France; Department of Orthopaedic surgery and Traumatology, University Hospital, Martinique, France. Electronic address:

Introduction: The understanding of the stresses and strains and their dependence on loading direction caused by an axial deformity is very important for understanding the mechanism of femural neck fractures. The hypothesis of this study is that lower limb malalignment is correlated with a substantial stress variation on the upper end of the femur. The purpose of this biomechanical trial using the finite element method is to determine the effect of the loading direction on the proximal femur regarding the malalignment of the lower limb, and also enlighten the relation between the lower limb alignment and the risk of a femoral neck fracture. Read More

Nat Rev Dis Primers 2022 04 28;8(1):26. Epub 2022 Apr 28.

Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indiana University, Indianapolis, IN, USA.

Bone stress injuries, including stress fractures, are overuse injuries that lead to substantial morbidity in active individuals. These injuries occur when excessive repetitive loads are introduced to a generally normal skeleton. Although the precise mechanisms for bone stress injuries are not completely understood, the prevailing theory is that an imbalance in bone metabolism favours microdamage accumulation over its removal and replacement with new bone via targeted remodelling. Read More

RSC Adv 2021 Jun 24;11(36):22327-22333. Epub 2021 Jun 24.

Department of Electrical and Computer Engineering, Sungkyunkwan University Suwon 16419 Republic of Korea

A monolithic integration of high-performance soft electronic modules into various fabric materials has enabled a paradigm shift in wearable textile electronics. However, the current textile electronics have struggled against fatigue under repetitive deformation due to the absence of materials and structural design strategies for imparting electrical and mechanical robustness to individual fibers. Here, we report a mechanically and electrically durable, stretchable electronic textile (MED-ET) enabled by a precisely controlled diffusion of tough self-healing stretchable inks into fibers and an adoption of the kirigami-inspired design. Read More

Proc Inst Mech Eng H 2022 Jun 21;236(6):825-840. Epub 2022 Apr 21.

Orthopaedics and Traumatology Department, Antalya Training and Research Hospital, Antalya, Turkey.

Malleolar screw fixation is the most widely used treatment method for medial malleolar (MM) fractures. Here, although buttress plate fixation is advocated for vertical MM fractures, the angular discrimination between oblique and vertical MM fractures is still not fully understood. The purpose of this study is to test the adequacy of screw fixation in MM fractures with different angles and determination of a 'critical fracture angle' to guide surgeons in the decision-making for screw fixation for MM fractures by utilizing an advanced engineering simulation approach. Read More

J Int Med Res 2022 Apr;50(4):3000605221091500

Orthopedic Department, Emek Medical Center, Afula, Israel.

Objective: Total hip arthroplasty (THA) involves postoperative risks, such as thigh pain, periprosthetic fractures, and stress yielding. Short, anatomical, metaphyseal-fitting, cementless femoral stems were developed to reduce these postoperative risks. This study aimed to examine the "MiniMAX" prosthesis, which is a new generation, short, anatomical femoral stem made by Medacta. Read More

Bone 2022 07 11;160:116420. Epub 2022 Apr 11.

Dept. of Endocrinology, Copenhagen University Hospital Hvidovre, Kettegaard Alle 30, 2650 Hvidovre, Denmark; Dept. of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3 B, 2200 Copenhagen, Denmark.

Background: Hypophosphatasia (HPP) is an autosomal recessive or dominate disease affecting bone mineralization, and adults with HPP are in risk to develop metatarsal stress fractures and femoral pseudofractures. Given to the scarce data on the bone quality and its association to the fracture risk in adults with HPP, this study aimed to evaluate bone turnover, bone strength and structure in adults with HPP.

Methods: In this cross-sectional study, we included 14 adults with genetically verified HPP and 14 sex-, age-, BMI-, and menopausal status-matched reference individuals. Read More

J Endod 2022 Jul 8;48(7):893-901. Epub 2022 Apr 8.

School of Dentistry, University of Queensland, Brisbane, Australia.

Introduction: This study aimed to investigate whether the direction of force applied to the occlusal surface influenced the pattern of tensile stresses in roots of sound and root canal-prepared mandibular molar teeth. The effect of obturation forces on the development of apical stress was also investigated. To this end, models were constructed using micro-computed tomographic imaging and investigated using finite element analysis. Read More

Injury 2022 Jun 31;53(6):2281-2286. Epub 2022 Mar 31.

Key Laboratory of Institutional Theory and Equipment Design, Ministry of Education, School of Mechanical Engineering, Tianjin University, 135 Yaguan Road, Jinnan District, Tianjin 300354, China.

Background: Early rehabilitation training after ankle fracture surgery is critical to healing and avoiding complications. Inappropriate or excessive motion may impede healing or even lead to secondary injury. Currently, there is a lack of scientific quantitative postoperative rehabilitation methods after ankle fracture. Read More

J Hand Surg Am 2022 Jun 6;47(6):534-539. Epub 2022 Apr 6.

Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA.

Purpose: Multifragmentary radial head and neck fractures not amenable to open reduction and internal fixation are usually treated with radial head arthroplasty (RHA). Although the optimal implant design is still subject to debate, anatomic designs are common. We hypothesized that positioning of the implant leading to increased radial stem angle (RSA) (angle of the RHA stem with respect to the proximal radius shaft, RSA) in anatomic RHA designs will contribute to failures. Read More