6,237 results match your criteria Streptococcus Group D Infections


Transcriptional activation by MafR, a global regulator of Enterococcus faecalis.

Sci Rep 2019 Apr 16;9(1):6146. Epub 2019 Apr 16.

Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.

Proteins that act as global transcriptional regulators play key roles in bacterial adaptation to new niches. These proteins recognize multiple DNA sites across the bacterial genome by different mechanisms. Enterococcus faecalis is able to survive in various niches of the human host, either as a commensal or as a leading cause of serious infections. Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-019-42484-4
Publisher Site
http://dx.doi.org/10.1038/s41598-019-42484-4DOI Listing
April 2019
1 Read

Uropathogens and their antimicrobial resistance patterns: Relationship with urinary tract infections.

Int J Health Sci (Qassim) 2019 Mar-Apr;13(2):48-55

Department of Pathology and Laboratory Medicine, College of Medicine, Qassim University, Saudi Arabia.

Objectives: This study was performed to determine the prevalence of uropathogens causing urinary tract infections (UTIs) and to determine their pattern of antimicrobial resistance.

Methods: This study was conducted on 273 urine samples collected from outpatient departments (OPDs) of Qassim University affiliated hospitals. Fully automated VITEK 2 compact system was used in the identification and antimicrobial susceptibility testing of causative microorganisms. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436442PMC

Proliferation rate and penicillin binding of enterococcal isolates from patients with immunosupression.

Lett Appl Microbiol 2019 Apr 13. Epub 2019 Apr 13.

Department of Pathology and Experimental Rheumatology, Medical University of Gdańsk, Gdańsk, Poland.

Low proliferation rate of bacterial populations was recently assumed to be a reason for higher resistance to antibiotics and appearance of many chronic infections. Slowly growing populations, called 'small colony variants' (SCVs) have been described in many bacterial species to make from as low as 0,02% up to 46% of population. Thirty enterococcal strains from urine and faeces of renal transplant recipients with asymptomatic, insignificant bacteriuria were studied. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/lam.13161DOI Listing

Characterization of the bacteriophage φEf11 ORF 28 endolysin: A multi-functional lytic enzyme with properties distinct from all other identified phage endolysins.

Appl Environ Microbiol 2019 Apr 12. Epub 2019 Apr 12.

Department of Endodontology, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA

φEf11 is a temperate, bacteriophage that infects strains of The φEf11 genome, encompassing 65 open reading frames (ORFs), is contained within 42,822 bp of DNA. Within this genome, a module of six lysis-related genes was identified. Based upon sequence homology, one of these six genes, ORF 28, was predicted to code for an N- acetylmuramoyl-L-alanine amidase endolysin of 46. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AEM.00555-19DOI Listing

Clinical and prognostic features of prosthetic joint infections caused by Enterococcus spp.

Eur Rev Med Pharmacol Sci 2019 Apr;23(2 Suppl):59-64

Department of Infectious Diseases, AORN Dei Colli, Naples, Italy.

Objective: Pathogens colonizing the intestinal or urinary tract such as enterococci or Gram-negative bacilli can cause prosthetic joint infection (PJI).

Patients And Methods: PJI undergoing 2-stage exchange, referred to the Department of Infectious Diseases of the Cotugno Hospital of Naples and the Fondazione Policlinico Gemelli of Rome over a 7-year period (2009-2015) for Infectious Diseases (ID) consultation were included. Demographic data, detailed information about previous or underlying diseases, findings of the clinical examination, and results of laboratory investigations were analyzed. Read More

View Article

Download full-text PDF

Source
http://www.europeanreview.org/article/17475
Publisher Site
http://dx.doi.org/10.26355/eurrev_201904_17475DOI Listing
April 2019
1 Read

Urinary tract infections after early removal of urinary catheter in total joint arthroplasty.

Eur Rev Med Pharmacol Sci 2019 Apr;23(2 Suppl):38-42

Department of Medical and Surgical Sciences, "Magna Graecia" University and "Mater Domini" University Hospital, Catanzaro, Italy.

Objective: Postoperative urine retention (POUR) is a well-known complication after total joint arthroplasty (TJA). POUR is most commonly managed with an indwelling catheter. However, indwelling catheters have been associated with a substantial risk of urinary tract infection (UTI). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26355/eurrev_201904_17472DOI Listing
April 2019
1 Read

Do liquid wastes from automated instruments in medical laboratories have their proper microbicide effect?

Ann Biol Clin (Paris) 2019 Apr 12. Epub 2019 Apr 12.

Laboratoire de virologie, Institut des agents infectieux, Groupement Hospitalier Nord des Hospices civils de Lyon, Lyon, France, Institut des sciences biologiques et pharmaceutiques de Lyon, Université Claude Bernard Lyon 1, Lyon, France, CIRI, Centre international de recherche en infectiologie, Équipe Virpath, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École normale supérieure de Lyon, Lyon, France.

Liquid wastes from clinical biology automated systems are currently evacuated in the urban network after chemical treatment to eliminate a possible risk of infection. Since these wastes are ecotoxic because of the presence of numerous chemical reagents, we studied their intrinsic microbicidal power towards a selection of infectious agents widely found in clinical specimens. The objective was to determine if an additional anti-infectious treatment before elimination is necessary. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/abc.2019.1431DOI Listing
April 2019
1 Read

H3N2 canine influenza virus and Enterococcus faecalis coinfection in dogs in China.

BMC Vet Res 2019 Apr 11;15(1):113. Epub 2019 Apr 11.

College of Veterinary Medicine, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing, 100193, China.

Background: In May 2017, 17 dogs in a German Shepherd breeding kennel in northern China developed respiratory clinical signs. The owner treated the dogs with an intravenous injection of Shuang-Huang-lian, a traditional Chinese medicine, and azithromycin. The respiratory signs improved 3 days post-treatment, however, cysts were observed in the necks of eight dogs, and three of them died in the following 2 days. Read More

View Article

Download full-text PDF

Source
https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
Publisher Site
http://dx.doi.org/10.1186/s12917-019-1832-xDOI Listing
April 2019
2 Reads

N-Methylation of Amino Acids in Gelatinase Biosynthesis-Activating Pheromone Identifies Key Site for Stability Enhancement with Retention of the Enterococcus faecalis fsr Quorum Sensing Circuit Response.

ACS Infect Dis 2019 Apr 19. Epub 2019 Apr 19.

Department of Chemistry , University of Nevada, Reno , 1664 N. Virginia Street , Reno , Nevada 89557 , United States.

The growing prevalence of multiantibiotic-resistant bacteria necessitates looking at potential alternative approaches for attenuating infections by bacteria while reducing the rate of antibiotic resistance development. Enterococcus faecalis is responsible for a large percentage of clinical enterococci infections, and its pathogenicity has been demonstrated to be influenced by quorum sensing (QS). In this study, we report the systematic study of the relationship between backbone hydrogens and the ability to activate the FsrC receptor. Read More

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acsinfecdis.9b00097
Publisher Site
http://dx.doi.org/10.1021/acsinfecdis.9b00097DOI Listing
April 2019
2 Reads

Impact of antibiotic treatment and host innate immune pressure on enterococcal adaptation in the human bloodstream.

Sci Transl Med 2019 Apr;11(487)

Department of Ophthalmology and Department of Microbiology, Harvard Medical School, Boston, MA 02114, USA.

Multidrug-resistant enterococcal strains emerged in the early 1980s and are now among the leading causes of drug-resistant bacterial infection worldwide. We used functional genomics to study an early bacterial outbreak in patients in a Wisconsin hospital between 1984 and 1988 that was caused by multidrug-resistant The goal was to determine how a clonal lineage of became adapted to growth and survival in the human bloodstream. Genome sequence analysis revealed a progression of increasingly fixed mutations and repeated independent occurrences of mutations in a relatively small set of genes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.aat8418DOI Listing

Genomic analysis of multidrug-resistant clinical isolates for antimicrobial resistance genes and virulence factors from the western region of Saudi Arabia.

Antimicrob Resist Infect Control 2019 25;8:55. Epub 2019 Mar 25.

1Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, 21589 Saudi Arabia.

Background: is a ubiquitous member of the gut microbiota and has emerged as a life- threatening multidrug-resistant (MDR) nosocomial pathogen. The aim of this study was to survey the prevalence of multidrug-resistant and epidemiologically important strains of in the western region of Saudi Arabia using phenotypic and whole genome sequencing approaches.

Methods: In total, 155 patients positive for infection were included in this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13756-019-0508-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434864PMC
March 2019
1 Read

Biofilm Forming Antibiotic Resistant Gram-Positive Pathogens Isolated From Surfaces on the International Space Station.

Front Microbiol 2019 19;10:543. Epub 2019 Mar 19.

Life Sciences and Technology, Microbiology, Beuth University of Applied Sciences, Berlin, Germany.

The International Space Station (ISS) is a closed habitat in a uniquely extreme and hostile environment. Due to these special conditions, the human microflora can undergo unusual changes and may represent health risks for the crew. To address this problem, we investigated the antimicrobial activity of AGXX®, a novel surface coating consisting of micro-galvanic elements of silver and ruthenium along with examining the activity of a conventional silver coating. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2019.00543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433718PMC

Ultrafast Parallelized Microfluidic Platform for Antimicrobial Susceptibility Testing of Gram Positive and Negative Bacteria.

Anal Chem 2019 Apr 15. Epub 2019 Apr 15.

Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College of Health Sciences , Northeastern University , 140 The Fenway , Boston , Massachusetts 02115 , United States.

Antimicrobial susceptibility testing (AST) is an essential diagnostic procedure to determine the correct course of treatment for various types of pathogen infections. Patients are treated with broad spectrum antibiotics until AST results become available, which has contributed to the emergence of multidrug resistant bacteria worldwide. Conventional AST methods require 16-24 h to assess sensitivity of the bacteria to a given drug and establish its minimum inhibitory concentration (MIC). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.9b00939DOI Listing

Bacteriophage resistance alters antibiotic mediated intestinal expansion of enterococci.

Infect Immun 2019 Apr 1. Epub 2019 Apr 1.

Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA, 80045

is a human intestinal pathobiont with intrinsic and acquired resistance to many antibiotics, including vancomycin. Nature provides a diverse and virtually untapped repertoire of bacterial viruses, or bacteriophages (phages), that could be harnessed to combat multi-drug resistant enterococcal infections. Bacterial phage resistance represents a potential barrier to the implementation of phage therapy, emphasizing the importance of investigating the molecular mechanisms underlying the emergence of phage resistance. Read More

View Article

Download full-text PDF

Source
http://iai.asm.org/lookup/doi/10.1128/IAI.00085-19
Publisher Site
http://dx.doi.org/10.1128/IAI.00085-19DOI Listing
April 2019
2 Reads

Structural Comparison of and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities.

Molecules 2019 Mar 31;24(7). Epub 2019 Mar 31.

Department of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2020, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.

Thymidylate synthase (TS) is an enzyme of paramount importance as it provides the only de novo source of deoxy-thymidine monophosphate (dTMP). dTMP, essential for DNA synthesis, is produced by the TS-catalyzed reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) using N⁵,N-methylenetetrahydrofolate (mTHF) as a cofactor. TS is ubiquitous and a validated drug target. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24071257DOI Listing

Therapeutic potential of medicinal plants for the management of urinary tract infection: A systematic review.

Clin Exp Pharmacol Physiol 2019 Apr 1. Epub 2019 Apr 1.

Department of Chemistry, Kohat University of Science and Technology, Kohat, Pakistan.

Urinary tract infection (UTI) is one of the most severe public health problem affecting both sexes but females are more susceptible due to the differences in urogenital and reproductive anatomy, physiology and lifestyle. As in UTI, different parts of the urinary tract are affected and morbidity due to UTI is more common in women of all ages and older men. Due to multi-drug resistant strains and high recurrence rate, UTI has become a major socioeconomic burden. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/1440-1681.13
Publisher Site
http://dx.doi.org/10.1111/1440-1681.13092DOI Listing
April 2019
9 Reads

Innovations in Worksite Diagnosis of Urinary Tract Infections and the Occupational Health Nurse.

Workplace Health Saf 2019 Mar 29:2165079919834310. Epub 2019 Mar 29.

2 GeneCapture, Inc.

Occupational health nurses play a key role in evaluating innovative technologies that can aid in providing safe and rapid care and reduce lost work time. A nurse-led employee health clinic participated in a validation study of a novel pathogen detection technique developed by GeneCapture, Inc. Their proposed portable urinary tract infection (UTI) in vitro diagnostic test was challenged with discarded, deidentified urine samples from patients presenting with typical UTI symptoms collected at two university clinics and two multiphysician practices. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2165079919834310DOI Listing

Virulence profiles of vancomycin-resistant enterococci isolated from surface and ground water utilized by humans in the North West Province, South Africa: a public health perspective.

Environ Sci Pollut Res Int 2019 Mar 28. Epub 2019 Mar 28.

Department of Microbiology, School of Biological Sciences, Faculty of Natural and Agricultural Sciences, North West University, Private Bag X2046, Mmabatho, 2735, South Africa.

Vancomycin-resistant enterococci (VRE) have been responsible for numerous outbreaks of serious infections in humans worldwide. Enterococcus faecium and Enterococcus faecalis are the principal species that are frequently associated with vancomycin resistance determinants, thus usually implicated in hospital- and community-acquired infections in humans. The study aim was to determine the antibiotic resistance and virulence profiles of VREs isolated from surface and groundwater samples that are used by humans in the North West Province, South Africa. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11356-019-04836-5DOI Listing
March 2019
2.828 Impact Factor

A Small-Molecule Inhibitor of -Translation Synergistically Interacts with Cathelicidin Antimicrobial Peptides To Impair Survival of Staphylococcus aureus.

Antimicrob Agents Chemother 2019 Apr 27;63(4). Epub 2019 Mar 27.

Department of Biology, Texas Christian University, Fort Worth, Texas, USA

is a leading cause of infection in the United States, and due to the rapid development of resistance, new antibiotics are constantly needed. -Translation is a particularly promising antibiotic target because it is conserved in many bacterial species, is critical for bacterial survival, and is unique among prokaryotes. We have investigated the potential of KKL-40, a small-molecule inhibitor of -translation, and find that it inhibits both methicillin-susceptible and methicillin-resistant strains of KKL-40 is also effective against Gram-positive pathogens, including a vancomycin-resistant strain of , , and , although its performance with Gram-negative pathogens is mixed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02362-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437501PMC

Lilla urinpose-syndrom.

Tidsskr Nor Laegeforen 2019 Mar 25;139(6). Epub 2019 Mar 25.

Background: Purple urine bag syndrome (PUBS) can occur in cases of bacteriuria with species expressing enzymes capable of converting tryptophan metabolites to red and blue pigments which are excreted in urine, leaving a characteristic purple colour. Risk factors include urinary catheterisation, constipation and chronic kidney disease. Treatment includes catheter replacement, and antibiotics in case of urinary tract infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4045/tidsskr.18.0677DOI Listing
March 2019
1 Read

Evaluation of antibacterial efficacy of sulfur nanoparticles alone and in combination with antibiotics against multidrug-resistant uropathogenic bacteria.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2019 Mar 26:1-10. Epub 2019 Mar 26.

a Nanobiotechnology Lab., Department of Biotechnology , SGB Amravati University , Amravati , India.

Urinary tract infections (UTIs) have been frequently reported from different parts of the world. The current knowledge on distribution of causative agents of urinary infections and antibiotics susceptibility pattern is essentially required. In the present study, total 351 uropathogenic bacteria were isolated; among them most prevalent were Escherichia coli (75%), followed by Pseudomonas aeruginosa (8%), Proteus mirabilis (6%), Klebsiella pneumoniae (4%), Staphylococcus aureus (4%) and Enterococcus faecalis (3%). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10934529.2018.1558892DOI Listing
March 2019
2 Reads

Role of , a previously uncharacterized gene, in biofilm development and antimicrobial resistance.

J Bacteriol 2019 Mar 25. Epub 2019 Mar 25.

Department of Microbiology and Immunology, University of Minnesota, Minneapolis MN

is a commensal of the human gastrointestinal tract; it is also an opportunistic pathogen and one of the leading causes of hospital-acquired infections. produces biofilms that are highly resistant to antibiotics and it has been previously reported that certain genes of the operon contribute to biofilm-associated antibiotic resistance. Despite several studies examining the operon, many gene products of this operon remain annotated as hypothetical proteins. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JB.00078-19DOI Listing

Prevalence of Bacterial Urinary Tract Infections and Associated Factors among Patients Attending Hospitals in Bushenyi District, Uganda.

Int J Microbiol 2019 17;2019:4246780. Epub 2019 Feb 17.

Department of Microbiology, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.

Urinary tract infections (UTIs) are one of the major causes of morbidity and comorbidities in patients with underlying conditions, and it accounts for the majority of the reasons for hospital visit globally. Sound knowledge of factors associated with UTI may allow timely intervention that can easily bring the disease under control. This study was designed to determine the prevalence of UTI by isolating and characterizing the different bacterial etiological agents and to evaluate the factors associated with UTI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/4246780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397969PMC
February 2019
2 Reads

Effect of Crude Bark Extracts Concentrations against Gram-Positive and Gram-Negative Bacterial Pathogens.

J Pharm Bioallied Sci 2019 Jan-Mar;11(1):33-37

Department of Pathology, Sri Lakshmi Narayana Institute of Medical Science Medical College and Hospital, Puducherry, India.

Background: Today's pharmaceutical markets are crowded with antibacterial agents, yet their toxicities and resistance are always contentious. is used in India as an age-old treatment for diverse medical conditions. This study was put forth to analyze the antibacterial action of bark extract on different bacterial pathogens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/jpbs.JPBS_150_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394162PMC
March 2019
2 Reads

Acute spinal implant infection treated with debridement: does extended antibiotic treatment improve the prognosis?

Eur J Clin Microbiol Infect Dis 2019 May 23;38(5):951-958. Epub 2019 Mar 23.

Infectious Diseases Department, University Hospital Vall d'Hebron, Universitat Autónoma de Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.

The study aims to determine whether 8 weeks of antibiotics is non-inferior to 12 weeks in patients with acute deep spinal implant infection (SII). In the retrospective study of all SII cases (2009-2016), patients aged ≥ 15 years with microbiologically confirmed SII treated with debridement and implant retention were included. Whenever possible, tailored antibiotic treatment was used: rifampin/linezolid in gram-positive and quinolones in gram-negative infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10096-019-03537-8DOI Listing
May 2019
2 Reads

First detection of an -positive, linezolid-resistant ST16 from human in Greece.

New Microbes New Infect 2019 May 7;29:100515. Epub 2019 Feb 7.

Department of Microbiology, University Hospital of Larissa, Larissa, Greece.

Until now, in Greece, the resistance of enterococci to linezolid was associated with mutations of domain V of 23S ribosomal RNA (G2576T). Here we report the first linezolid-resistant -positive sequence type (ST) 16 isolated from a patient with a urinary tract infection (UTI). No travels overseas, contact with food-producing animals or previous treatment with linezolid were reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nmni.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406052PMC

Temporal and Geographic Variation in Antimicrobial Susceptibility and Resistance Patterns of Enterococci: Results From the SENTRY Antimicrobial Surveillance Program, 1997-2016.

Open Forum Infect Dis 2019 Mar 15;6(Suppl 1):S54-S62. Epub 2019 Mar 15.

JMI Laboratories, North Liberty, Iowa.

Background: The SENTRY Antimicrobial Surveillance Program was established in 1997 and presently encompasses more than 750 000 bacterial isolates from over 400 medical centers worldwide. Among these pathogens, enterococci represents a prominent cause of bloodstream (BSIs), intra-abdominal (IAIs), skin and skin structure, and urinary tract infections (UTIs). In the present study, we reviewed geographic and temporal trends in species and resistant phenotypes identified throughout the SENTRY Program. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ofid/ofy344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419914PMC

Comparison of antimicrobial activity of traditional and new developed root sealers against pathogens related root canal.

J Dent Sci 2018 Mar 1;13(1):54-59. Epub 2018 Feb 1.

Department of Oral Microbiology and Immunology, College of Dentistry, Dankook University, Cheonan, Republic of Korea.

Background/purpose: Bacterial infection is closely associated with the failure of endodontic treatment, and use of endodontic sealer with antimicrobial activity and biological compatibility is necessary for the success of root canal treatment. The purpose of this study was to investigate and to compare the antibacterial effect of two calcium silicate-based root canal sealers (Endoseal and EndoSequence BC sealer) as recent development sealers and with three conventional root canal sealers (AH Plus, Sealapex, and Tubli-Seal), before or after setting, on , and

Materials And Methods: The sealers were soaked in phosphate buffered saline to elute its compositions after and before setting, and the elutes were performed the antimicrobial assay. Also, X-ray fluorescence analysis was carried out to compare compositions of two calcium silicate-based sealers. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19917902183003
Publisher Site
http://dx.doi.org/10.1016/j.jds.2017.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388800PMC
March 2018
2 Reads

Analysis of a poxtA- and optrA-co-carrying conjugative multiresistance plasmid from Enterococcus faecalis.

J Antimicrob Chemother 2019 Mar 19. Epub 2019 Mar 19.

College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, PR China.

Objectives: To investigate the presence and transferability of the poxtA gene and identify the genetic context of poxtA in two enterococcal plasmids from swine.

Methods: MICs were determined by broth microdilution. A total of 114 porcine enterococci with florfenicol MICs of ≥16 mg/L were screened for the presence of the poxtA gene by PCR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dkz109DOI Listing
March 2019
1 Read

Autosplenectomy in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH).

Case Rep Hematol 2019 12;2019:3146965. Epub 2019 Feb 12.

Houston Methodist Hospital, Department of Medicine, 6550 Fannin St, Houston, TX 77030, USA.

Autosplenectomy (AS) is a known complication of diseases such as sickle cell anemia, celiac disease, and inflammatory bowel disease. We report the first known case of AS due to paroxysmal nocturnal hemoglobinuria (PNH). A 24-year-old Caucasian male had evidence of hemolytic anemia at the age of 14 and was diagnosed with PNH at the age of 16. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/3146965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390241PMC
February 2019
5 Reads

Infections and outcomes after cardiac surgery-The impact of outbreaks traced to transesophageal echocardiography probes.

Acta Anaesthesiol Scand 2019 Mar 19. Epub 2019 Mar 19.

Department of Anaesthesia and Intensive Care, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.

Background: Infections are a frequent complication of cardiac surgery. The intraoperative use of transesophageal echocardiography (TEE) may be an underrecognized risk factor for post-operative infections. The aim of this study was to investigate infection rates and outcomes after cardiac surgery in a nationwide cohort, especially in relation to periods where surface damaged TEE probes were used. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aas.13360DOI Listing
March 2019
3 Reads

The prevalence of antiseptic tolerance genes among staphylococci and enterococci in a pediatric population.

Infect Control Hosp Epidemiol 2019 Mar;40(3):333-340

Department of Pediatrics, Section of Infectious Diseases,Baylor College of Medicine and Texas Children's Hospital,Houston, Texas.

Objective: The smr and qacA/B genes in Staphylococcus aureus confer tolerance to antiseptics and are associated with nosocomial acquisition of infection and underlying medical conditions. Such antiseptic tolerance (AT) genes have also been reported in coagulase-negative staphylococci (CoNS) and enterococci, however, few data are available regarding their prevalence. We sought to describe the frequency of AT genes among bloodstream isolates of S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/ice.2019.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425960PMC

Use of a subcutaneous ureteral bypass device for treatment of bilateral proximal ureteral injury in a 9-month-old cat.

JFMS Open Rep 2019 Jan-Jun;5(1):2055116919831856. Epub 2019 Mar 11.

The Animal Referral Hospital Homebush, NSW, Australia.

Case Summary: A 9-month-old male domestic longhair cat presented following iatrogenic ureteral trauma after an attempted laparoscopic ovariectomy. Prior to identifying that the cat was male, both ureters were transected approximately 4 mm from the renal pelves. Initial management involved a left-sided Boari flap neoureterocystostomy, cystonephropexy and right ureteronephrectomy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2055116919831856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415474PMC
March 2019
7 Reads

Bacterial infiltration in structural heart valve disease.

J Thorac Cardiovasc Surg 2019 Feb 20. Epub 2019 Feb 20.

Department of Cardiac Surgery, Ludwig-Maximilians-University, Munich, Germany.

Objectives: The pathology of structural valvular heart disease (sVHD) ranges from basic diseases of rheumatologic origin to chronic degenerative remodeling processes after acute bacterial infections. Molecular genetic methods allow detection of the complete microbial spectrum in heart valve tissues independent of microbiological cultivation. In particular, whole-metagenome analysis is a sensitive and highly specific analytical method that allows a deeper insight into the pathogenicity of the diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtcvs.2019.02.019DOI Listing
February 2019

In vitro activities of daptomycin combined with fosfomycin or rifampin on planktonic and adherent linezolid-resistant isolates of Enterococcus faecalis.

J Med Microbiol 2019 Mar;68(3):493-502

1 Department of Infectious Diseases and the Key Lab of Endogenous Infection, Shenzhen Nanshan People's Hospital and The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen 518052, PR China.

Purpose: This study aimed to explore daptomycin combined with fosfomycin or rifampin against the planktonic and adherent linezolid-resistant isolates of Enterococcus faecalis.

Methodology: Four linezolid-resistant and four linezolid-sensitive isolates of E. faecalis which formed biofilms were collected for this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/jmm.0.000945DOI Listing
March 2019
1 Read

Comparison of genotypes, antimicrobial resistance and virulence profiles of oral and non oral Enterococcus faecalis from Brazil, Japan and the United Kingdom.

J Dent 2019 Mar 9. Epub 2019 Mar 9.

School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.

Objectives: To determine whether phenotypic and genotypic differences amongst isolates ofEnterococcus faecalis relate to geographical and clinical origin.

Methods: E. faecalis from primary endodontic infections in Brazilian patients (n = 20), oral infections in UK patients (n = 10), and non-oral infections in Japanese patients (n = 9) were studied. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdent.2019.03.002DOI Listing
March 2019
1 Read

Parasitoid envenomation alters the Galleria mellonella midgut microbiota and immunity, thereby promoting fungal infection.

Sci Rep 2019 Mar 8;9(1):4012. Epub 2019 Mar 8.

Institute of Systematics and Ecology of Animals, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630091, Russia.

Gut bacteria influence the development of different pathologies caused by bacteria, fungi and parasitoids in insects. Wax moth larvae became more susceptible to fungal infections after envenomation by the ectoparasitoid Habrobracon hebetor. In addition, spontaneous bacterioses occurred more often in envenomated larvae. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-40301-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408550PMC
March 2019
2 Reads

A Retrospective Cohort Study of Risk Factors for Surgical Site Infection Following Liver Transplantation.

Prog Transplant 2019 Mar 7:1526924819835831. Epub 2019 Mar 7.

1 Graduate Program in Adult Health Nursing, School of Nursing, University of São Paulo, São Paulo, Brazil.

Background:: Surgical site infection is an important complication in the postoperative period among liver transplant recipients. However, little is known about the risk factors in this patient group. Therefore, the objective of this study was to analyze the incidence and risk factors for surgical site infections among adult liver transplant recipients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1526924819835831DOI Listing
March 2019
1 Read

Distribution of main Gram-positive pathogens causing bloodstream infections in United States and European hospitals during the SENTRY Antimicrobial Surveillance Program (2010-2016): concomitant analysis of oritavancin in vitro activity.

J Chemother 2018 Sep;30(5):280-289

a JMI Laboratories , North Liberty , Iowa , USA.

This study updates the distribution and trends of Gram-positive organisms causing bloodstream infections (BSIs) in the United States (US) and Europe during 2010-2016. In vitro activities of oritavancin and comparators were also evaluated. Staphylococcus aureus, Enterococcus spp. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/1120009X.2018.1
Publisher Site
http://dx.doi.org/10.1080/1120009X.2018.1516272DOI Listing
September 2018
7 Reads

Fighting Pathogenic Bacteria on Two Fronts: Phages and Antibiotics as Combined Strategy.

Front Cell Infect Microbiol 2019 18;9:22. Epub 2019 Feb 18.

Institute of Medical Microbiology, RWTH Aachen University Hospital, Aachen, Germany.

With the emerging threat of infections caused by multidrug resistant bacteria, phages have been reconsidered as an alternative for treating infections caused by tenacious pathogens. However, instead of replacing antibiotics, the combination of both types of antimicrobials can be superior over the use of single agents. Enhanced bacterial suppression, more efficient penetration into biofilms, and lowered chances for the emergence of phage resistance are the likely advantages of the combined strategy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2019.00022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387922PMC
February 2019
1 Read

Molecular characterization of vancomycin-resistant enterococci isolated from a hospital in Beijing, China.

J Microbiol Immunol Infect 2019 Feb 11. Epub 2019 Feb 11.

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. Electronic address:

Objective: To investigate the occurrence of vancomycin-resistant enterococci (VRE) isolated from patients in Peking Union Medical College Hospital, Beijing, China from 2011 to 2017, and to evaluate their resistance mechanisms and genetic relatedness.

Methods: All isolates were identified using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF). Antibiotic susceptibility testing was performed using the broth microdilution method. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmii.2018.12.008DOI Listing
February 2019
3 Reads

Early alert from microbiology laboratory improves the outcome of elderly patients with Enterococcus spp bacteremia: results from a multicenter prospective study.

J Glob Antimicrob Resist 2019 Feb 27. Epub 2019 Feb 27.

Internal Medicine Ward, Ospedale Civile, Legnano, Italy.

Objectives: To describe clinical features and outcome of patients with bloodstream infections (BSIs) due to Enterococcus spp and identify predictive factors of mortality.

Methods: This analysis is part of a prospective multicenter observational study of consecutive hospitalized patients with BSIs. The study was conducted from March 2012 to December 2012 in 31 Internal Medicine wards (IMWs) in Italy (SNOOPII study). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jgar.2019.02.014DOI Listing
February 2019
1 Read

A relative assessment of essential oil of and along with calcium hydroxide and chlorhexidine gel against in root canal models.

J Conserv Dent 2019 Jan-Feb;22(1):34-39

Department of Molecular Bioprospection, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, Uttar Pradesh, India.

Objective: The objective of this study was to evaluate the antibacterial efficacy of two doses of vetiver and chamomile essential oils compared with chlorhexidine and calcium hydroxide against .

Materials And Methods: The growth inhibition and minimum inhibitory concentration of all tested materials were determined following agar diffusion and broth dilution assay procedure. Human maxillary anterior teeth were prepared with protaper rotary files, followed by incubation with standard broth of . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/JCD.JCD_69_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385582PMC
March 2019
9 Reads

d-Serine Degradation by Proteus mirabilis Contributes to Fitness during Single-Species and Polymicrobial Catheter-Associated Urinary Tract Infection.

mSphere 2019 02 27;4(1). Epub 2019 Feb 27.

Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA

is a common cause of catheter-associated urinary tract infection (CAUTI) and secondary bacteremia, which are frequently polymicrobial. We previously utilized transposon insertion-site sequencing (Tn-Seq) to identify novel fitness factors for colonization of the catheterized urinary tract during single-species and polymicrobial infection, revealing numerous metabolic pathways that may contribute to fitness regardless of the presence of other cocolonizing organisms. One such "core" fitness factor was d-serine utilization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/mSphere.00020-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393727PMC
February 2019
3 Reads

Efficacy of teicoplanin monotherapy following initial standard therapy in Enterococcus faecalis infective endocarditis: a retrospective cohort study.

Infection 2019 Feb 27. Epub 2019 Feb 27.

Department of Infectious and Tropical Diseases, Toulouse University Hospital, Place du Docteur Baylac TSA 40031, 31059, Toulouse CEDEX 9, France.

Purpose: Teicoplanin is often used in Enterococcus faecalis infective endocarditis as a relay in case of penicillin side effects, or in outpatients. We assessed the efficacy of teicoplanin used as continuation therapy after initial standard treatment of E. faecalis endocarditis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s15010-019-01290-wDOI Listing
February 2019

Ceftobiprole activity when tested against contemporary bacteria causing bloodstream infections in the United States (2016-2017).

Diagn Microbiol Infect Dis 2019 Jan 26. Epub 2019 Jan 26.

JMI Laboratories, North Liberty, Iowa, USA.

Ceftobiprole medocaril, the prodrug of ceftobiprole, is an advanced-generation cephalosporin that is approved in many European and non-European countries for the treatment of adults with hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia and is currently being evaluated in a global phase 3 clinical trial of patients with Staphylococcus aureus bacteremia. This study investigated the in vitro activity of ceftobiprole and comparators against a total of 5466 gram-positive and -negative isolates from bloodstream infections (BSIs) that were collected in the United States during 2016 and 2017 as part of the SENTRY Antimicrobial Surveillance Program. Ceftobiprole was highly active (isolates were >99% susceptible) against S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.diagmicrobio.2019.01.015DOI Listing
January 2019
3 Reads

Efficacy of Injectable and Immersion Polyvalent Vaccine against Streptococcal Infections in Broodstock and Offspring of Nile tilapia (Oreochromis niloticus).

Fish Shellfish Immunol 2019 May 23;88:293-300. Epub 2019 Feb 23.

Department of Infectious Disease, Faculty of Veterinary Medicine, Cairo University, Egypt. Middle East for Veterinary Vaccines Company, Second Industrial Area, ElSalihya El-Gededa, El-Sharkia, 44671, Egypt. Electronic address:

A vaccine against streptococcosis, lactococcosis and enterococcosis in tilapia was formulated, ME-VAC Aqua Strept, as a polyvalent inactivated vaccine containing Streptococcus agalactiae, S. iniae, Lactococcus garvieae and Enterococcus faecalis along with a nano-particulate adjuvant. Use of ME-VAC Aqua Strept by injection or immersion resulted in an improved non-specific and adaptive immunity of broodstock and offspring. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fsi.2019.02.042DOI Listing
May 2019
1 Read

Loop-mediated isothermal amplification assay for Enterococcus sp., E. coli and S. aureus in chicken.

FEMS Microbiol Lett 2019 Feb 26. Epub 2019 Feb 26.

Avian disease division, Animal and Plant Quarantine Agency, HyukSin 8-ro, GimCheon, Republic of Korea.

Bacterial chondronecrosis with osteomyelitis (BCO) is a major cause of lameness in broiler chicken, and results in serious economic losses worldwide. Although the pathogenesis mechanism leading to lameness is not entirely understood, some strains of Enterococcus sp., avian pathogenic Escherichia coli, or Staphylococcus aureus have been long recognized as important causative pathogens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/femsle/fnz042DOI Listing
February 2019
1 Read

Micro-organisms attached to the lumens and balloons of indwelling urinary catheters and correlation with symptoms, antibiotic use and catheter specimen of urine results.

J Med Microbiol 2019 Apr 26;68(4):549-554. Epub 2019 Feb 26.

1 Biomaterials-Related Infection Group, School of Medicine, University of Nottingham, Nottingham, UK.

To determine micro-organisms attached to removed urethral catheters and relate this to patient-specific information. Indwelling urethral catheters were collected from patients at a UK teaching hospital. The balloon and lumen were sonicated, and micro-organisms were enumerated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/jmm.0.000946DOI Listing
April 2019
2 Reads

Update of the therapeutic planning of irrigation and intracanal medication in root canal treatment. A literature review.

J Clin Exp Dent 2019 Feb 1;11(2):e185-e193. Epub 2019 Feb 1.

Endodontic and restorative dentistry Associate Professor, Universidad Europea de Valencia, España.

Background: The success of endodontic treatment derives from the complete elimination of microorganisms capable of causing an intraradicular or extraradicular infection. To achieve a more effective eradication of these microorganisms, endodontic instrumentation must always be implemented with abundant irrigation, which has to achieve chemical, mechanical and biological effects. The irrigators most used today are NaOCl, CHX and EDTA, released into the ducts through different techniques such as syringe, manual agitation, positive or negative apical pressure, sonic or ultrasonic activation, PIPS and PDT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4317/jced.55560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383907PMC
February 2019