6,941 results match your criteria Streptococcus Group D Infections

Assessment of disinfectant efficacy in reducing microbial growth.

PLoS One 2022 27;17(6):e0269850. Epub 2022 Jun 27.

Reference Laboratory for Microbiology, Executive Department of Reference Laboratories, Research and Laboratories Sector, Saudi Food and Drug Authority (SFDA), Riyadh, Saudi Arabia.

The incidence of hospital- and community-acquired infections has been dramatically increased worldwide. Accordingly, hands hygiene and the use of disinfectants have been increased leading to the expansion in hand sanitizers production to meet public demand. This study was conducted to assess the efficiency of common disinfectants in the market of Riyadh, Saudi Arabia in inhibiting the microbial growth during the time of Coronavirus disease 2019 (COVID-19) pandemic. Read More

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Enterococcus faecalis Antagonizes Pseudomonas aeruginosa Growth in Mixed-Species Interactions.

J Bacteriol 2022 Jun 27:e0061521. Epub 2022 Jun 27.

Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological Universitygrid.59025.3b, Singapore.

Enterococcus faecalis is often coisolated with Pseudomonas aeruginosa in polymicrobial biofilm-associated infections of wounds and the urinary tract. As a defense strategy, the host innately restricts iron availability at infection sites. Despite their coprevalence, the polymicrobial interactions of these two species in biofilms and under iron-restricted conditions remain unexplored. Read More

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Structure-activity relationship studies for inhibitors for vancomycin-resistant and human carbonic anhydrases.

J Enzyme Inhib Med Chem 2022 Dec;37(1):1838-1844

Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN, USA.

Vancomycin-resistant enterococci (VRE), consisting of pathogenic , is a leading cause of hospital-acquired infections (HAIs). We recently repurposed the FDA-approved human carbonic anhydrase (CA) inhibitor acetazolamide () against VRE agent with the likely mechanism of action for the molecules being inhibition of one, or both, of the bacterial CA isoforms expressed in VRE. To elucidate how inhibitor binding to the enzymes relates to MIC, we further characterised the inhibition constants () against the α-CA (-CA) and γ-CA (γ-CA), as well as against human CA I (hCAI) and human CA II (hCAII) to assess selectivity. Read More

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December 2022

The antibacterial activity of mineral trioxide aggregate containing calcium fluoride.

J Dent Sci 2022 Apr 9;17(2):836-841. Epub 2021 Oct 9.

Songha Yoo Seunghoon Pediatric Dentistry, Cheonan, South Korea.

Background/purpose: Because complete microbial elimination of the infected root canal system is nearly impossible to achieve, the use of root canal fillings with antibacterial effects may help to minimize intracanal infections. Our previous study, MTA modified by CaF addition, improved the biocompatibility and mineralization potential of human dental pulp cells without adverse effect on the physical properties. In this study, the antibacterial effect of MTA after CaF addition was evaluated for use as a root canal sealer. Read More

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Bacteriophage-Resistant Mutant of Is Impaired in Biofilm Formation.

Front Microbiol 2022 9;13:913023. Epub 2022 Jun 9.

Department of Microbiology, Army Medical University, Chongqing, China.

is a common gram-positive non-spore-forming bacterium in nature and is found in the upper respiratory tract, intestine, and mouth of healthy people. is also one of the common pathogens causing nosocomial infections and is resistant to several antibiotics commonly used in practice. Thus, treating drug-resistant with antibiotics is challenging, and new approaches are needed. Read More

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Increasing adult density compromises survival following bacterial infections in Drosophila melanogaster.

J Insect Physiol 2022 Jun 23:104415. Epub 2022 Jun 23.

Department of Biological Sciences, Indian Institute of Science Education and Research, Mohali, India. Electronic address:

The density-dependent prophylaxis hypothesis predicts that risk of pathogen transmission increases with increase in population density, and in response to this, organisms mount a prophylactic immune response when exposed to high density. This prophylactic response is expected to help organisms improve their chances of survival when exposed to pathogens. Alternatively, organisms living at high densities can exhibit compromised defense against pathogens due to lack of resources and density associated physiological stress; the crowding stress hypothesis. Read More

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Risk Factors for Catheter-Associated Urinary Tract Infections (CAUTI) in the Pediatric Intensive Care Unit.

Indian Pediatr 2022 Jun 11. Epub 2022 Jun 11.

Department of Biostatistics, St. John's Medical College and Hospital, Bengaluru, Karnataka.

Objective: To describe the occurrence, microbiology, and risk factors of catheter- associated urinary tract infections (CA-UTI) in critically ill children.

Methods: We conducted a review of hospital records for CA-UTI in the pediatric intensive care unit (PICU) over a 7-year period (2014-2020).

Results: 62-CAUTI cases (48% boys, median (IQR) age 36 (12,96 month) were identified during the study period with occurrence rate of 7. Read More

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Silver-doped phosphate coacervates to inhibit pathogenic bacteria associated with wound infections: an in vitro study.

Sci Rep 2022 Jun 24;12(1):10778. Epub 2022 Jun 24.

Department of Chemistry, University of Surrey, Guildford, GU27XH, UK.

There is a great demand from patients requiring skin repair, as a result of poorly healed acute wounds or chronic wounds. These patients are at high risk of constant inflammation that often leads to life-threatening infections. Therefore, there is an urgent need for new materials that could rapidly stimulate the healing process and simultaneously prevent infections. Read More

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Biosensors for with Molecularly Imprinted Polymer (MIP) Technique.

Sensors (Basel) 2022 Jun 20;22(12). Epub 2022 Jun 20.

Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.

Nosocomial infection is one of the most important problems that occurs in hospitals, as it directly affects susceptible patients or patients with immune deficiency. ( is the most common cause of nosocomial infections in hospitals. can cause various diseases such as pneumonia, urinary tract infections, septicemias, and soft tissue infections, and it has also become highly resistant to antibiotics. Read More

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Targeting Persistent Biofilm Infections: Reconsidering the Topography of the Infection Site during Model Selection.

Microorganisms 2022 Jun 6;10(6). Epub 2022 Jun 6.

Department of Endodontics, Goldschleger School of Dental Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.

The physiology of an organism in the environment reflects its interactions with the diverse physical, chemical, and biological properties of the surface. These principles come into consideration during model selection to study biofilm-host interactions. Biofilms are communities formed by beneficial and pathogenic bacteria, where cells are held together by a structured extracellular matrix. Read More

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Bacterial Resistance to Antibiotics and Clonal Spread in COVID-19-Positive Patients on a Tertiary Hospital Intensive Care Unit, Czech Republic.

Antibiotics (Basel) 2022 Jun 8;11(6). Epub 2022 Jun 8.

Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 3, 779 00 Olomouc, Czech Republic.

This observational retrospective study aimed to analyze whether/how the spectrum of bacterial pathogens and their resistance to antibiotics changed during the worst part of the COVID-19 pandemic (1 November 2020 to 30 April 2021) among intensive care patients in University Hospital Olomouc, Czech Republic, as compared with the pre-pandemic period (1 November 2018 to 30 April 2019). A total of 789 clinically important bacterial isolates from 189 patients were cultured during the pre-COVID-19 period. The most frequent etiologic agents causing nosocomial infections were strains of (17%), (11%), (10%), coagulase-negative staphylococci (9%), (8%), (6%), (5%), (5%) and (5%). Read More

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Revisiting the Frequency and Antimicrobial Resistance Patterns of Bacteria Implicated in Community Urinary Tract Infections.

Antibiotics (Basel) 2022 Jun 3;11(6). Epub 2022 Jun 3.

Department of Biology & CESAM, University of Aveiro, 3810-193 Aveiro, Portugal.

Urinary tract infections (UTIs) are one of the most common infectious diseases at the community level. The continue misuse of antimicrobials is leading to an increase in bacterial resistance, which is a worldwide problem. The objective of this work was to study the incidence and pattern of antimicrobial resistance of the main bacteria responsible for UTI in the community of central and northern Portugal, and establish an appropriate empirical treatment. Read More

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Heteroaryl-Ethylenes as New Effective Agents for High Priority Gram-Positive and Gram-Negative Bacterial Clinical Isolates.

Antibiotics (Basel) 2022 Jun 3;11(6). Epub 2022 Jun 3.

Section of Microbiology, Department of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95123 Catania, Italy.

The World Health Organization has identified antimicrobial resistance as a public health emergency and developed a global priority pathogens list of antibiotic-resistant bacteria that can be summarized in the acronym ESKAPE (, , , , and species), reminding us of their ability to escape the effect of antibacterial drugs. We previously tested new heteroaryl-ethylene compounds in order to define their spectrum of activity and antibacterial capability. Now, we focus our attention on PB4, a compound with promising MIC and MBC values in all conditions tested. Read More

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Multicenter Evaluation of the Novel ETEST Fosfomycin for Antimicrobial Susceptibility Testing of Enterobacterales, Enterococcus faecalis, and Staphylococcus Species.

J Clin Microbiol 2022 Jun 23:e0002122. Epub 2022 Jun 23.

bioMérieux, La Balme les Grottes, France.

Fosfomycin is a phosphonic acid derivative active against a wide spectrum of Gram-positive and Gram-negative pathogens. It is used for the treatment of uncomplicated urinary tract infections (uUTI) or severe infections by oral or intravenous (i.v. Read More

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Mixed Skin and Soft Tissue Infection Caused by and in a Diabetic Patient: A Case Report.

Maedica (Bucur) 2022 Mar;17(1):211-214

Department of Internal Medicine, University Hospital of Heraklion, Crete, Greece.

is a widely distributed fungus that has evolved as an important pathogen, especially in immunocompromised individuals, causing fungemias, central nervous system infections, peritoneal dialysis-associated peritonitis and keratitis. Even though there are a few reports of skin and soft tissue infections caused by , all these cases involve immunocompromised individuals. is a Gram-positive bacterium known to cause several infections such as bloodstream, urinary tract and skin and soft tissue infections. Read More

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Assessment of Antimicrobial Activity of Ethanolic and Aqueous Extracts of L. (Horse Chestnut) Bark against Bacteria Isolated from Urine of Patients Diagnosed Positive to Urinary Tract Infections.

Front Biosci (Schol Ed) 2022 Apr;14(2):11

Department of Biology and General Genetics, Institute of Medicine, RUDN University, 117198 Moscow, Russia.

The search for new antimicrobials is essential to address the worldwide issue of antibiotic resistance. The present work aimed at assessing the antimicrobial activity of L. (horse chestnut) bark against bacteria involved in urinary tract infections (UTIs). Read More

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Microbial diversity and antimicrobial susceptibility in endotracheal tube biofilms recovered from mechanically ventilated COVID-19 patients.

Biofilm 2022 Dec 14;4:100079. Epub 2022 Jun 14.

Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.

In patients with acute respiratory failure, mechanical ventilation through an endotracheal tube (ET) may be required to correct hypoxemia and hypercarbia. However, biofilm formation on these ETs is a risk factor for infections in intubated patients, as the ET can act as a reservoir of microorganisms that can cause infections in the lungs. As severely ill COVID-19 patients often need to be intubated, a better knowledge of the composition of ET biofilms in this population is important. Read More

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December 2022

Dissemination of Quinupristin-Dalfopristin and Linezolid resistance genes among hospital environmental and healthy volunteer fecal isolates of Enterococcus faecalis and Enterococcus faecium.

Mol Biol Rep 2022 Jun 18. Epub 2022 Jun 18.

Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Streptogramins and linezolid are important in the treatment of infections caused by vancomycin-resistant enterococci.

Purpose: Then, we aimed to evaluate the resistance rates against these drugs and the prevalence of genes involved in hospital environmental and fecal normal-flora isolates of Enterococcus faecalis and Enterococcus faecium.

Methods And Results: The strains were isolated from the stool samples and hospital environments by culturing on M-Enterococcus (ME) agar, and identified by phenotypic and genotypic microbiological tests. Read More

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Enhanced Eradication of Biofilms by Quaternized Chitosan-Coated Upconversion Nanoparticles for Photodynamic Therapy in Persistent Endodontic Infections.

Front Microbiol 2022 31;13:909492. Epub 2022 May 31.

Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.

Due to the persistent presence of biofilms in apical root canals, persistent endodontic infections (PEIs) have always been an intractable disease to solve. The conventional root canal disinfectants (e.g. Read More

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Inhibitory Effects of Carvacrol on Biofilm Formation and Expression of Biofilm Related Genes in Clinical Isolates of Enterococcus faecalis.

Clin Lab 2022 Jun;68(6)

Background: Nowadays, novel antimicrobial strategies are being developed which focus on debilitating, rather than killing the microorganisms. In this regard, anti-biofilm therapy is one of the important ways to combat bacterial infections. Therefore, the aim of the current study was to evaluate the anti-biofilm activity of Carvacrol against E. Read More

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Antimicrobial Susceptibility Testing for Enterococci.

J Clin Microbiol 2022 Jun 13:e0084321. Epub 2022 Jun 13.

Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA.

Enterococci are major, recalcitrant nosocomial pathogens with a wide repertoire of intrinsic and acquired resistance determinants and the potential of developing resistance to all clinically available antimicrobials. As such, multidrug-resistant enterococci are considered a serious public health threat. Due to limited treatment options and rapid emergence of resistance to all novel agents, the clinical microbiology laboratory plays a critical role in deploying accurate, reproducible, and feasible antimicrobial susceptibility testing methods to guide appropriate treatment of patients with deep-seated enterococcal infections. Read More

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H, C, and N resonance assignments of a conserved putative cell wall binding domain from Enterococcus faecalis.

Biomol NMR Assign 2022 Jun 4. Epub 2022 Jun 4.

School of Biosciences, University of Sheffield, Firth Court, Western Bank, S10 2TN, Sheffield, UK.

Enterococcus faecalis is a major causative agent of hospital acquired infections. The ability of E. faecalis to evade the host immune system is essential during pathogenesis, which has been shown to be dependent on the complete separation of daughter cells by peptidoglycan hydrolases. Read More

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Linezolid for resistant Gram-positive bacterial infections in children under 12 years: A meta-analysis.

Open Med (Wars) 2022 26;17(1):969-977. Epub 2022 May 26.

Department of Respiratory and Critical Care Medicine, People's Hospital of Quzhou, Quzhou 324000, Zhejiang Province, China.

Both linezolid and vancomycin have good efficacy in the treatment of resistant Gram-positive bacterial infections. This systematic review and meta-analysis aimed to compare the efficacy and safety of linezolid vs vancomycin for the treatment of resistant Gram-positive bacterial infections in children under 12 years. Five randomly controlled trials involving 638 children that were treated with linezolid and vancomycin for resistant Gram-positive bacterial infections were searched from medical databases. Read More

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Microbial Infection and Antibiotic Susceptibility of Diabetic Foot Ulcer in China: Literature Review.

Front Endocrinol (Lausanne) 2022 19;13:881659. Epub 2022 May 19.

Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.

Objective: To investigate the microbial spectrum isolated from foot ulcers among diabetic patients in China, which was conducted to help clinicians choose optimal antibiotics empirically.

Method: The PubMed, MEDLINE, Web of Science, China Biology Medicine (CBM), China National Knowledge Infrastructure (CNKI), WanFang, and VIP databases were searched for studies published between 2015 to 2019, that report primary data on diabetic foot infection (DFI) and antibiotic susceptibility in China.

Result: A total of 63 articles about DFI and antibiotic susceptibility tests among diabetic patients in China were included. Read More

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Macrophage depletion alters bacterial gut microbiota partly through fungal overgrowth in feces that worsens cecal ligation and puncture sepsis mice.

Sci Rep 2022 Jun 4;12(1):9345. Epub 2022 Jun 4.

Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.

Because macrophage dysfunction from some emerging therapies might worsen gut-derived sepsis, cecal ligation and puncture (CLP) sepsis are performed in mice with clodronate-induced macrophage depletion. Macrophage depletion (non-sepsis) increased fecal Ascormycota, with a subtle change in bacterial microbiota, that possibly induced gut-barrier defect as Candida pintolopesii and Enterococcus faecalis were identified from blood. Sepsis in macrophage-depleted mice was more severe than sepsis control as indicated by mortality, cytokines, organ injury (liver, kidney, and spleen), gut-leakage (FITC-dextran), fecal Proteobacteria, and blood organisms (bacteria and fungi). Read More

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Comparative Evaluation of Antibacterial Efficacy of Silver and Cadmium Nanoparticles and Calcium Hydroxide against Biofilm.

J Contemp Dent Pract 2021 Dec 1;22(12):1438-1443. Epub 2021 Dec 1.

Department of Conservative Dentistry and Endodontics, SMBT Dental College and Hospital, Sangamner, Maharashtra, India.

Aim: The purpose of this study was to evaluate and compare the antibacterial efficacy of calcium hydroxide medicament, silver (AgNPs) and cadmium nanoparticles (CdSNPs) as medicament against the biofilms of on dentin sections. is commonly detected in asymptomatic and persistent endodontic infections.

Methods: Twenty standard size dentin sections were prepared. Read More

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December 2021

Profile of the Nasopharyngeal Microbiota Affecting the Clinical Course in COVID-19 Patients.

Front Microbiol 2022 17;13:871627. Epub 2022 May 17.

Aix-Marseille Université, Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Microbes Evolution Phylogeny and Infections (MEPHI), Marseille, France.

While populations at risk for severe SARS-CoV-2 infections have been clearly identified, susceptibility to the infection and its clinical course remain unpredictable. As the nasopharyngeal microbiota may promote the acquisition of several respiratory infections and have an impact on the evolution of their outcome, we studied the nasopharyngeal microbiota of COVID-19 patients in association with baseline disease-related clinical features compared to that of patients tested negative. We retrospectively analyzed 120 nasopharyngeal pseudonymized samples, obtained for diagnosis, divided into groups (infected patients with a favorable outcome, asymptomatic, and deceased patients) and patients tested negative for SARS-CoV-2, by using Illumina-16S ribosomal ribonucleic acid (rRNA) sequencing and specific polymerase chain reaction (PCR) targeting pathogens. Read More

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and dual-species biofilm: establishment of an protocol and characterization.

Biofouling 2022 Apr 2;38(4):401-413. Epub 2022 Jun 2.

Department of Pathology and Legal Medicine, Federal University of Ceará, Fortaleza, Brazil.

is the most important agent of persistent apical periodontitis, and recently, has also been implicated in periapical infections. This study aimed to optimize an and dual-species biofilm protocol for endodontic research. Different physicochemical conditions for biofilm formation were tested. Read More

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Bacterial Adhesion and Biofilm Formation of on Zwitterionic Methylmethacrylat and Polysulfones.

Front Cell Infect Microbiol 2022 16;12:868338. Epub 2022 May 16.

Division of Tropical Medicine and Infectious Diseases, Center of Internal Medicine II, University Medical Center, Rostock, Germany.

Biofilm-associated implant infections represent a major challenge for healthcare systems around the world due to high patient burden and enormous costs incurred. is the most prevalent enterococcal species identified in biofilm-associated infections. The steadily growing areas of application of implants demand a solution for the control of bacterial infections. Read More

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Farnesol as a potentiator of antimicrobial photodynamic inactivation on Enterococcus faecalis.

Photodiagnosis Photodyn Ther 2022 May 26:102928. Epub 2022 May 26.

Institute of Science and Technology of São Paulo State University/UNESP, São José dos Campos, SP, Brazil.

Enterococcus faecalis is related to the recurrence of endodontic infections and complementary approaches to intracanal disinfection are necessary. Farnesol, an alcohol commonly found in propolis, has antimicrobial properties, and can enhance the efficacy of some antibiotic therapies. The objective was to evaluate whether farnesol can increase the efficacy of the antimicrobial photodynamic inactivation (aPDI) on E. Read More

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