22,350 results match your criteria Strabismus [Journal]
Invest Ophthalmol Vis Sci 2018 Dec;59(15):5816-5822
Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, Maryland, United States.
Purpose: Stereoscopic vision, by detecting interocular correlations, enhances depth perception. Stereodeficiencies often emerge during the first months of life, and left untreated can lead to severe loss of visual acuity in one eye and/or strabismus. Early treatment results in much better outcomes, yet diagnostic tests for infants are cumbersome and not widely available. Read More
Int J Retina Vitreous 2018 30;4:45. Epub 2018 Nov 30.
Gavin Herbert Eye Institute, University of California Irvine, 850 Health Sciences Road, Irvine, CA 92697 USA.
Background: Prader-Willi syndrome (PWS) is a genetic disease caused by loss of expression of the paternally inherited copy of several genes on the long arm of chromosome 15. Ophthalmic manifestations of PWS include strabismus, amblyopia, nystagmus, hypopigmentation of the iris and choroid, diabetic retinopathy, cataract and congenital ectropion uvea. An overlap between PWS and oculocutaneous albinism (OCA) has long been recognized and attributed to deletion of OCA2 gene located in PWS critical region (PWCR). Read More
Genes (Basel) 2018 Dec 4;9(12). Epub 2018 Dec 4.
Department of Ophthalmology, Stanford University School of Medicine, 1651 Page Mill Road, Palo Alto, CA 94305, USA.
Joubert syndrome is a group of rare disorders that stem from defects in a sensory organelle, the primary cilia. Affected patients often present with disorders involving multiple organ systems, including the brain, eyes, and kidneys. Common symptoms include breathing abnormalities, mental developmental delays, loss of voluntary muscle coordination, and abnormal eye movements, with a diagnostic "molar tooth" sign observed by magnetic resonance imaging (MRI) of the midbrain. Read More
J Community Genet 2018 Dec 1. Epub 2018 Dec 1.
University of Minnesota Medical School, Duluth campus, Minneapolis, MN, USA.
To determine the association of consanguinity with the occurrence of genetically transmitted eye diseases in rural and urban populations in Pavagada and Madhugiri taluks, Karnataka state, south India. This study was part of a population based cross-sectional prevalence survey, "The Pavagada pediatric eye disease study 2." As a part of the demographic data, trained investigators collected information on consanguinity from the parents of children identified for the study. Read More
Can J Ophthalmol 2018 Dec 5;53(6):621-626. Epub 2018 Apr 5.
Department of Ophthalmology, McGill University, Montréal, Qué.
Objective: To characterize the ocular response to retrobulbar anaesthesia and to evaluate the efficacy of retrobulbar anaesthesia for adjustable strabismus surgery in adults.
Design: Prospective observational study.
Participants: Adult patients undergoing adjustable strabismus surgery under retrobulbar anaesthesia. Read More
Can J Ophthalmol 2018 Dec 7;53(6):609-613. Epub 2018 Apr 7.
McGill Vision Research, Department of Ophthalmology, McGill University, Montreal, Que. Electronic address:
Objective: Both genetic and environmental factors are thought to play a role in the pathogenesis of strabismus and subsequent ocular dominance and amblyopia. Our purpose was to compare the characteristics of sensory visual function in 2 adult monozygotic (genetically identical) twins who presented with esotropia at different ages.
Methods: Monocular and binocular visual function was measured in the twins. Read More
Curr Opin Neurol 2018 Dec 3. Epub 2018 Dec 3.
Departments of Ophthalmology and Pediatrics, Emory University, Atlanta, Georgia, USA.
Purpose Of Review: To review the recent advances in understanding how primary brain tumors affect vision in children.
Recent Findings: Children with primary brain tumors may have vision loss due to involvement of their afferent visual pathways or from papilledema. These vision deficits may go unrecognized until later in life, years after treatment of the primary lesion. Read More
Am J Med Genet A 2018 Dec 4. Epub 2018 Dec 4.
Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel.
Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues. Arginine methylation is involved in multiple biological processes, such as signal transduction, mRNA splicing, transcriptional control, DNA repair, and protein translocation. Currently, 10 patients have been described with mutations in PRMT7. Read More
Dev Med Child Neurol 2018 Dec 3. Epub 2018 Dec 3.
MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, UK.
Aim: To systematically review and meta-analyse studies of neurodevelopmental outcome of children born to mothers prescribed methadone in pregnancy.
Method: MEDLINE, Embase, and PsycINFO were searched for studies published from 1975 to 2017 reporting neurodevelopmental outcomes in children with prenatal methadone exposure.
Results: Forty-one studies were identified (2283 participants). Read More
Acta Ophthalmol 2018 Dec 3. Epub 2018 Dec 3.
Department of Ophthalmology, Haukeland University Hospital, Bergen, Norway.
Purpose: To evaluate the results of surgical treatment in a large group of patients with trochlear nerve palsy, with emphasis on the self-grading effect of a standardized recession of the ipsilateral inferior oblique muscle.
Methods: All patients who underwent first-time surgery for trochlear nerve palsy in the period 2005-2014 in our department (n = 114) were retrospectively evaluated regarding pre- and postoperative data, surgical procedure, and the need for reoperations. Mean follow-up time was 8. Read More
Vestn Oftalmol 2018 ;134(5. Vyp. 2):178-185
Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.
One of the most common and potentially threatening manifestations of granulomatosis with polyangiitis (GPA) is orbital lesion.
Purpose: To study the clinical course and prognosis of orbital lesions of various localization in GPA patients. Material and me-thods. Read More
J Ophthalmic Vis Res 2018 Oct-Dec;13(4):461-469
B.P. Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Maharajgunj Medical Campus, Tribhuvan University, Maharajgunj, Kathmandu, Nepal.
Purpose: To collect information regarding awareness and knowledge of eye health and diseases among the population of the hilly region of Nepal.
Methods: In a population-based survey, 1834 participants were enrolled in to the study. Field procedures included the development of a survey questionnaire, field orientation, pretesting, and household data collection. Read More
Int Ophthalmol 2018 Nov 26. Epub 2018 Nov 26.
Department of Medical Biology and Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
Purpose: Duane retraction syndrome (DS) is a rare congenital strabismus with genetic heterogeneity. The genetic causes of DS are not always of monogenic origin; various chromosomal copy number variations (CNVs) have also been reported. The objective of our study was to characterize the CNVs, including gains and losses detected by high-resolution chromosomal microarray in patients with DS. Read More
Pediatrics 2018 Dec;142(6)
This policy statement revises a previous statement on screening of preterm infants for retinopathy of prematurity (ROP) that was published in 2013. ROP is a pathologic process that occurs in immature retinal tissue and can progress to a tractional retinal detachment, which may then result in visual loss or blindness. For more than 3 decades, treatment of severe ROP that markedly decreases the incidence of this poor visual outcome has been available. Read More
Turk J Haematol 2018 Nov 26. Epub 2018 Nov 26.
Department of Molecular Biology-Genetics and Biotechnology, Graduate School of Science, Engineering and Technology, Istanbul Technical University, Turkey.
Objective: Autosomal recessive cutis laxa type IIA (ARCL2A) is a rare congenital disorder characterized by loose and elastic skin, growth and developmental delay, and skeletal anomalies. It is caused by biallelic mutations in . Those mutations lead to increased pH in secretory vesicles and thereby to impaired glycosyltransferase activity and organelle trafficking. Read More
BMC Ophthalmol 2018 Nov 23;18(1):305. Epub 2018 Nov 23.
Department of Ophthalmology, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa School of Medicine, 34098, Fatih, Istanbul, Turkey.
Background: Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity of additional surgeries in the treatment of thyroid orbitopathy related strabismus. In this study, reviewing the results of our patients who had surgical correction with relaxed muscle positioning technique due to thyroid orbitopathy related strabismus to evaluate the effectiveness of the surgery was aimed.
Methods: The medical records of 8 patients who had surgical correction with intraoperative relaxed muscle positioning (IRMP) technique were studied retrospectively. Read More
J Med Genet 2018 Nov 21. Epub 2018 Nov 21.
Genetics and Molecular Medicine Department and Pediatric Institute of Rare Diseases (IPER), Hospital Sant Joan de Déu, Barcelona, Spain.
Introduction: Phosphomannomutase-2 deficiency (PMM2-CDG) is associated with a recognisable facial pattern. There are no early severity predictors for this disorder and no phenotype-genotype correlation. We performed a detailed dysmorphology evaluation to describe facial gestalt and its changes over time, to train digital recognition facial analysis tools and to identify early severity predictors. Read More
BMC Ophthalmol 2018 Nov 21;18(1):302. Epub 2018 Nov 21.
Department of Ophthalmology, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st RD, Kaohsiung, 81346, Taiwan.
Background: Amblyopia is a main concern in children undergoing frontalis sling surgery for repairing congenital ptosis. This study aimed to evaluate factors related to amblyopia in children undergoing frontalis sling surgery.
Methods: IRB-approved retrospective review of children under the age of 12 who received frontalis sling surgery. Read More
Eur J Ophthalmol 2018 Nov 21:1120672118795066. Epub 2018 Nov 21.
2 Department of Ophthalmology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, PA, USA.
Purpose:: To report the results of bilateral lateral rectus muscle recession for recurrent exotropia in cases where the primary surgery was a bilateral medial rectus resection.
Methods:: Retrospective chart review of 15 subjects who completed 6 months of follow-up. Data collected included patients' demographics and pre- and post-operative measurements of ocular alignment and motility. Read More
Cyberpsychol Behav Soc Netw 2018 Nov 17. Epub 2018 Nov 17.
1 Department of Ophthalmology, Guangdong Eye Institute , Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China .
We evaluated the effect of dichoptic visual training based on a unique virtual reality (VR) platform mounted display in patients with intermittent exotropia (IXT). A total of 25 IXT patients (8 men, 17 women) with a mean age of 12.3 years (range, 5-39 year) were recruited. Read More
J Helminthol 2018 Nov 20:1-6. Epub 2018 Nov 20.
Department of Ophthalmology,Faculty of Medicine,Zagazig University,Egypt.
Uveitis is one of the commonest causes of vision loss worldwide and its exact etiology is still not clarified in most patients. The current study is a trial to assess the efficacy of serum anti-Toxocara immunoglobulin G (IgG) by enzyme-linked immunosorbent assay (ELISA) as a diagnostic tool for ocular toxocariasis (OT) and to detect OT prevalence and the associated ocular manifestations in sera of patients with uveitis. One hundred and twelve patients (62 females and 50 males) with uveitis were diagnosed by ophthalmologists, radiologists and rheumatologists according to ocular manifestations, laboratory and radiological investigations. Read More
Ophthalmology 2018 Dec;125(12):1968
Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York.
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):412
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):407-411
Purpose: To examine stereopsis in patients with comitant horizontal strabismus who had normal vision and were stereoblind following the strabismus surgery.
Methods: Twenty patients with primary comitant horizontal strabismus and normal corrected visual acuity were included in this study. The stereoacuity was quantitatively measured by the random dot butterfly stereotest, the Randot Preschool Stereoacuity Test (Stereo Optical, Inc. Read More
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):403-406
Purpose: To analyze the yearly refractive trend in patients with stage 3 retinopathy of prematurity (ROP) over a 7-year time period.
Methods: This was a retrospective review of 70 eyes of 35 patients with stage 3 ROP.
Results: Of the 70 eyes, 46 received laser ablation and 24 did not. Read More
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):397-402
Purpose: To review systemic associations of childhood glaucoma.
Methods: Patients younger than 15 years and diagnosed as having glaucoma were divided into four groups: isolated primary congenital glaucoma, glaucoma with other congenital ocular anomalies, congenital glaucoma with known systemic diseases, and secondary glaucoma. Prevalence and type of systemic associations in each group were studied. Read More
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):355
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):353-354
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):352
J Pediatr Ophthalmol Strabismus 2018 Nov;55(6):348-351
JAMA Ophthalmol 2018 Nov 15. Epub 2018 Nov 15.
School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia.
Importance: Reading and eye-hand coordination deficits in children with amblyopia may impede their ability to demonstrate their knowledge and skills, compete in sports and physical activities, and interact with peers. Because perceived scholastic, social, and athletic competence are key determinants of self-esteem in school-aged children, these deficits may influence a child's self-perception.
Objective: To determine whether amblyopia is associated with lowered self-perception of competence, appearance, conduct, and global self-worth and whether the self-perception of children with amblyopia is associated with their performance of reading and eye-hand tasks. Read More
J AAPOS 2018 Nov 14. Epub 2018 Nov 14.
Department of Ophthalmology, Columbia University Irving Medical Center, New York, New York. Electronic address:
J AAPOS 2018 Nov 13. Epub 2018 Nov 13.
Pediatric Ophthalmology and Strabismus, Alaska Children's EYE & Strabismus, Anchorage, Alaska; Chugach Anesthesia, Anchorage, Alaska.
Ophthalmic Genet 2018 Dec 16;39(6):735-740. Epub 2018 Nov 16.
a Department of Pediatric Ophthalmology, Strabismus, and Adult Motility , Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center , Pittsburgh , Pennsylvania , USA.
Background: Posterior column ataxia retinitis pigmentosa (PCARP) with feline leukemia virus subgroup C cellular receptor 1 (FLVCR1) gene mutation is a rare disorder with significant ophthalmic features.
Materials And Methods: We conducted a retrospective case series study of patients diagnosed with PCARP and genetic testing positive for FLVCR1 mutation between 1 January 2015 and 1 October 2017 at the Children's Hospital of Pittsburgh. Clinical charts, visual fields, fundus autofluorescence, and spectral-domain optical coherence tomography (SD-OCT) were reviewed. Read More
Zhonghua Yan Ke Za Zhi 2018 Nov;54(11):849-854
Department of Ophthalmology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
To investigate the clinical characteristics, surgical approaches and postoperative effects associated with congenital fibrovascular pupillary membranes. A retrospective study design was used. Thirteen children (13 eyes) with congenital fibrovascular pupillary membranes, treated in Beijing Children's Hospital from January 2014 to December 2017 were included. Read More
Biochem Med (Zagreb) 2018 Oct;28(3):030801
Department of Pediatrics, University Hospital Center Zagreb, Zagreb, Croatia.
Gyrate atrophy (GA) of the choroid and retina is a rare autosomal recessive disorder that occurs due to deficiency of the mitochondrial enzyme ornithine aminotransferase (OAT). Hyperornithinemia causes degeneration of the retina with symptoms like myopia, reduced night vision and progressive vision loss. Our patient is a 10-year-old girl with impaired vision and strabismus. Read More
Acta Biochim Pol 2018 11 14. Epub 2018 Nov 14.
Department of Ophthalmology, Poznan University of Medical Sciences, Poznan, Poland.
Long non-coding RNAs are 200 nucleotide long RNA molecules which lack or have limited protein-coding potential. They can regulate protein formation through several different mechanisms. Similarly, circular RNAs are reported to play a critical role in post-transcriptional gene regulation. Read More
Ophthalmic Genet 2018 Dec 14;39(6):725-727. Epub 2018 Nov 14.
a Department of Ophthalmology , Centre Hospitalier Universitaire de Sherbrooke , Sherbrooke , Quebec , Canada.
Background: Leigh syndrome, French Canadian type is a rare neurodegenerative disease. To our knowledge, there have been no studies based on ocular findings published for this disease. The purpose of this study is to describe ophthalmic findings in these patients. Read More
Chin Med J (Engl) 2018 Nov;131(22):2705-2712
Department of Neurology, Research Institute of Neuromuscular and Neurodegenerative Diseases, Qilu Hospital, Shandong University, Jinan, Shandong 250012, China.
Background: Leigh syndrome (LS) is a rare disease caused by mitochondrial defects and has high phenotypic and genotypic heterogeneity. We analyzed the clinical symptoms, neuroimaging, muscular histopathology, and genotypes of 13 Chinese LS patients with mitochondrial DNA (mtDNA) mutations.
Methods: Mutations in mtDNA were identified by targeted sequencing. Read More
Acta Ophthalmol 2018 Nov 6. Epub 2018 Nov 6.
Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
The effect of maternal smoking during pregnancy on strabismus in offspring remains unclear. We conducted a meta-analysis to summarize epidemiological evidences on the association between maternal smoking during pregnancy and the risk of offspring strabismus. Eligible studies were searched from the PubMed, Ovid, Embase and CNKI databases up to May 2018. Read More
Zhonghua Er Ke Za Zhi 2018 Nov;56(11):846-849
Department of Neurology, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
To investigate the clinical features, laboratory characteristics and genetic diagnosis of Kabuki syndrome (KS). Between September 2014 and September 2016, seven children with clinically diagnosed KS from the neurology department, Beijing Children Hospital, Capital Medical University were included in this study. Three of them were male and 4 were female aged from 19 days to 6 years and 4 months with a median age of 3 years and 1 month. Read More
Purinergic Signal 2018 Nov 3. Epub 2018 Nov 3.
General hospital of Tianjin Medical University, Tianjin, 300052, China.
Physiologically, retinal pigment epithelium (RPE) expresses high levels of CD73 in their membrane, converting AMP to immune suppressive adenosine, mediates an anti-inflammatory effect. However, after being exposed to inflammatory factors, RPE rapidly becomes CD73-negative cells, which render RPE's immune suppressive function and accelerate local inflammation. Here, we investigated the mechanism leading to the loss of membrane CD73 in RPE. Read More
J Pediatr Ophthalmol Strabismus 2018 Nov 2;55:e39-e41. Epub 2018 Nov 2.
A case of a 4 year-old boy with persistent fetal vasculature, lenticular coloboma, and a benign, multiloculated ciliary body mass is reviewed. The presence of ciliary body cysts in association with persistent fetal vasculature is sparsely reported. Its presence in a child can cause a diagnostic dilemma and lead to amblyopia. Read More
J Pediatr Ophthalmol Strabismus 2018 Nov 2;55:e36-e38. Epub 2018 Nov 2.
A 2-year-old boy with Alagille syndrome who had esotropia underwent bilateral medial rectus recession. One month postoperatively, esotropia reoccurred and was aggravated thereafter. Right lateral rectus resection was unsuccessful because the insertion site could not be identified. Read More
J Pediatr Ophthalmol Strabismus 2018 Nov 2;55:e33-e35. Epub 2018 Nov 2.
Anisocoria is a significant finding in several ocular and potentially life-threatening neurological disorders. The angel's trumpet (Datura suaveolens), widely used as a garden plant, is a natural alkaloid with anticholinergic effects containing high levels of scopolamine. The authors present a pediatric case of acute anisocoria secondary to contact with the angel's trumpet plant. Read More
Surv Ophthalmol 2018 Oct 29. Epub 2018 Oct 29.
Departments of Ophthalmology and Neurology, Mayo Clinic, Rochester, MN.
A 74-year-old woman experienced chronic painless progressive binocular horizontal diplopia for two years. Initial examination showed a visual acuity of 20/20 OU. External exam and slit lamp exam was unremarkable. Read More
Graefes Arch Clin Exp Ophthalmol 2018 Oct 31. Epub 2018 Oct 31.
Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
Purpose: To investigate the extent of adhesion and changes in the Y configuration after the Y-split procedure, compared with the posterior fixation suture.
Methods: Twelve New Zealand white rabbits were included in the study. The 10-mm Y-split procedure was performed in the superior rectus muscle (SR) of one eye, and the 10-mm posterior fixation suture was made in the SR of the other eye. Read More
Ther Adv Ophthalmol 2018 Jan-Dec;10:2515841418806492. Epub 2018 Oct 24.
Department of Ophthalmology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.
Purpose: To describe the use of enhanced iris images and a computer software program to quantify ocular torsional changes associated with head tilt.
Methods: Pixel coordinates of the pupil and different iris landmarks were obtained manually using paint program from digital images of the right and left iris of 3 subjects with normal extraocular motility. Photographs of the right eye and of the left eye were taken in the straight-ahead position and at various degrees of right and left head tilt. Read More
Curr Eye Res 2018 Oct 30. Epub 2018 Oct 30.
g State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center , Sun Yat-sen University , Guangzhou , China.
Purpose: The aim of this study was to examine the functional connectivity between the primary visual cortex and other cortical areas during rest in normal subjects and patients with comitant strabismus using functional magnetic resonance imaging (fMRI).
Methods: A prospective, observational study was conducted. Ten patients with comitant exotropia and eleven matched healthy subjects underwent resting-state fMRI with their eyes closed. Read More