267,932 results match your criteria Stomach


Gastrointestinal: Glomus tumor: A rare submucosal tumor of the stomach.

J Gastroenterol Hepatol 2019 Jan 21. Epub 2019 Jan 21.

Department of Gastroenterology and Hepatology, Japanese Red Cross Osaka Hospital, Osaka, Japan.

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http://dx.doi.org/10.1111/jgh.14594DOI Listing
January 2019

A new application of dual knife: easier removal of a giant gastric bezoar.

Dig Endosc 2019 Jan 21. Epub 2019 Jan 21.

Department of Gastroenterology, Nanchong Central Hospital, Nanchong City, Sichuan, 637000, China.

The video presentation had been agreed by the patient and his sons. A 70-year-old man was admitted to our emergency department for hematemesis. On November 2, 2018, he underwent gastroscopy (GIF450; Fujinon; Japan) that revealed a giant bezoar occupying the thoracic portion of the stomach (Fig. Read More

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http://dx.doi.org/10.1111/den.13348DOI Listing
January 2019

Impact of emulsifier nature and concentration on the stability of β-carotene enriched nanoemulsions during in vitro digestion.

Food Funct 2019 Jan 21. Epub 2019 Jan 21.

Department of Food Technology, University of Lleida-Agrotecnio Centre, Rovira Roure 191, 25198 Lleida, Spain.

The presence of emulsifiers facilitates the formation of nanoemulsions and assists in their stabilisation. Moreover, behaviour of nanoemulsions along the gastrointestinal tract primarily depends on their composition, affecting the bioaccessibility of the encapsulated compound. The goal of this work was to study how β-carotene-enriched nanoemulsions prepared with different emulsifiers (Tween 20, lecithin, sodium caseinate, sucrose palmitate) at various concentrations (2%-8%) would affect their stability (particle size and zeta potential) during an in vitro gastrointestinal tract (GIT) digestion. Read More

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http://dx.doi.org/10.1039/c8fo02069hDOI Listing
January 2019

Preclinical evaluation of a novel thermally sensitive co-polymer (LiftUp) for endoscopic resection.

Minim Invasive Ther Allied Technol 2019 Jan 19:1-8. Epub 2019 Jan 19.

f Department of Gastroenterology, Vivantes Klinikum in Friedrichshain , Teaching Hospital of Charité Humboldt University , Berlin , Germany.

Introduction: Endoscopic resection techniques can successfully resect large lesions either in "en bloc" fashion or in "piece-meal" technique by using a submucosal injection solution. The aim of this study was to evaluate the safety of a novel injectable, containing thermally sensitive co-polymer from ethylenoxide and propylenoxide (LiftUp) used as submucosal injection solution.

Material And Methods: We conducted an in vivo animal trial in the porcine model to evaluate the LiftUp gel in a preclinical setting and to study the effectiveness of mucosal lifting and the safety of the new injectable. Read More

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http://dx.doi.org/10.1080/13645706.2018.1535440DOI Listing
January 2019

Development of Lactobacillus kimchicus DCY51-mediated gold nanoparticles for delivery of ginsenoside compound K: in vitro photothermal effects and apoptosis detection in cancer cells.

Artif Cells Nanomed Biotechnol 2019 Dec;47(1):30-44

a Department of Oriental Medicinal Biotechnology, College of Life Science , Kyung Hee University , Yongin-si , Republic of Korea.

We report a non-covalent loading of ginsenoside compound K (CK) onto our previously reported gold nanoparticles (DCY51-AuCKNps) through one-pot biosynthesis using a probiotic Lactobacillus kimchicus DCY51 isolated from Korean kimchi. The ginsenoside-loaded gold nanoparticles were characterized by various analytical and spectroscopic techniques such as field emission transmission electron microscopy (FE-TEM), energy-dispersive X-ray (EDX) spectroscopy, elemental mapping, X-ray powder diffraction (XRD), selected area electron diffraction (SAED), Fourier-transform infrared (FTIR) spectroscopy and dynamic light scattering (DLS). Furthermore, drug loading was also determined by liquid chromatography-mass spectrometry (LC-MS). Read More

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https://www.tandfonline.com/doi/full/10.1080/21691401.2018.1
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http://dx.doi.org/10.1080/21691401.2018.1541900DOI Listing
December 2019

Determination and comparison of alkaloids and triterpenes among tissues after oral administration of crude and processed Phellodendri Chinensis Cortex by UPLC-QqQ-MS.

Nat Prod Res 2019 Jan 19:1-4. Epub 2019 Jan 19.

a School of Pharmacy , Liaoning University of Traditional Chinese Medicine , Dalian , China.

Phellodendri Chinensis Cortex is widely used in the clinic of traditional Chinese medicine. In order to enlarge the range of application, it is necessary to processed with honey, salt-water, and rice-wine, respectively. We hope to elucidate the connotation of processing, an UPLC-QqQ-MS method was used for determination and comparison the tissue distribution of alkaloids and triterpenes after oral administration water-extracts of crude and processed products. Read More

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http://dx.doi.org/10.1080/14786419.2018.1560293DOI Listing
January 2019

LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.

J Cancer 2019 1;10(1):156-167. Epub 2019 Jan 1.

Department of Colorectal and Anus Surgery, Xiangya Hospital of Central South University, Hunan key laboratory of precise diagnosis and treatment of gastrointestinal tumor, Changsha, Hunan, P.R. China.

LXRα is a subtype of the liver X receptors (LXRs). There is accumulating evidence to support the involvement of LXRα in a variety of malignancies. However, the function and specific mechanism of LXRα in gastric cancer (GC) remain unclear. Read More

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http://dx.doi.org/10.7150/jca.28600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329868PMC
January 2019

The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins.

Front Pharmacol 2018 4;9:1515. Epub 2019 Jan 4.

Department of Clinical Nutrition, University of Texas Southwestern Medical Center, Dallas, TX, United States.

The mevalonate pathway provides sterols for membrane structure and nonsterol intermediates for the post-translational modification and membrane anchorage of growth-related proteins, including the Ras, Rac, and Rho GTPase family. Mevalonate-derived products are also essential for the Hedgehog pathway, steroid hormone signaling, and the nuclear localization of Yes-associated protein and transcriptional co-activator with PDZ-binding motif, all of which playing roles in tumorigenesis and cancer stem cell function. The phosphatidylinositol-4,5-bisphosphate 3-kinase-AKT-mammalian target of rapamycin complex 1 pathway, p53 with gain-of-function mutation, and oncoprotein MYC upregulate the mevalonate pathway, whereas adenosine monophosphate-activated protein kinase and tumor suppressor protein RB are the downregulators. Read More

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http://dx.doi.org/10.3389/fphar.2018.01515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328495PMC
January 2019

Colon targeted beads loaded with pterostilbene: Formulation, optimization, characterization and evaluation.

Saudi Pharm J 2019 Jan 20;27(1):71-81. Epub 2018 Jul 20.

Department of Pharmacology, Bombay College of Pharmacy, Kalina, Santacruz (E), Mumbai 400098, India.

Background: Pterostilbene has a proven chemopreventive effect for colon carcinogenesis but suffers low bioavailability limitations and therefore unable to reach the colonic tissue.

Objective And Methodology: To overcome the issue of low bioavailability, pterostilbene was formulated into an oral colon targeted beads by ionic gelation method using pectin and zinc acetate. Optimization was carried out by 2 factorial design whereby the effect of pectin concentration (), zinc acetate concentration () and pterostilbene:pectin ratio () were studied on entrapment efficiency () and drug release till 24 h (). Read More

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http://dx.doi.org/10.1016/j.jsps.2018.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323150PMC
January 2019

[PRIMARY SMALL CELL NEUROENDOCRINE CARCINOMA OF THE URETER].

Nihon Hinyokika Gakkai Zasshi 2018 ;109(1):30-34

Departments of Pathology, Kinki Central Hospital of Mutual Aid Association of Public Teachers.

Primary small cell neuroendocrine carcinoma of the upper urinary tract is a rare disease that is associated with a poor prognosis. An 81-year-old man was diagnosed with carcinoma of the stomach and underwent laparoscopic distal gastrectomy. Computed tomography (CT) revealed carcinoma of the left ureter and left hydronephrosis. Read More

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http://dx.doi.org/10.5980/jpnjurol.109.30DOI Listing
January 2018

RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment.

Crit Rev Oncol Hematol 2019 Jan 3;133:85-91. Epub 2018 Nov 3.

Department of Histopathology, Antwerp University Hospital, Edegem, B2650, Belgium.

Binding between the receptor activator of nuclear factor-kB (RANK) and its ligand (RANKL) triggers recruitment of TNF receptor associated factor (TRAF) adaptor proteins and activation of downstream pathways. RANK/RANKL signaling is controlled by a decoy receptor called osteoprotegerin (OPG) which interacts with RANKL. Additional networks regulating RANK/RANKL signaling are active in a context specific manner. Read More

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http://dx.doi.org/10.1016/j.critrevonc.2018.10.011DOI Listing
January 2019

Laparoscopic repair of type III/IV giant para-oesophageal herniae with biological prosthesis: a single centre experience.

Hernia 2019 Jan 19. Epub 2019 Jan 19.

Department of Surgery, EKHUFT, Ashford, Kent, UK.

Purpose: Repair of giant paraoesophageal herniae (GPEH) is technically challenging and requires significant experience in advanced foregut surgery. Controversy continues on suture versus mesh cruroplasty with the most recent systematic review and meta-analysis putting the onus on the operating surgeon. Study aim was to review whether the biological prosthesis (non-cross-linked bovine pericardium and porcine dermis) and the technique adopted for patients with GPEH had an influence on clinical and radiological recurrences. Read More

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http://dx.doi.org/10.1007/s10029-019-01888-xDOI Listing
January 2019

Acid-happy: Survival and recovery of enteropathogenic Escherichia coli (EPEC) in simulated gastric fluid.

Microb Pathog 2019 Jan 17. Epub 2019 Jan 17.

Water and Health Research Centre, University of Johannesburg, Doornfontein, South Africa.

Background: Gastric fluid pH serves an important function as an ecological filter to kill unwanted microbial taxa that would otherwise colonise the intestines, thereby shaping the diversity and composition of microbial communities found in the gut. The typical American-based diet causes the gastric pH to increase to pH 4 to 5, and it takes ∼2 h to return to pH 1.5 (normal). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08824010183182
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http://dx.doi.org/10.1016/j.micpath.2019.01.022DOI Listing
January 2019
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Patterns of mercury and selenium in tissues and stomach contents of the dolphinfish Coryphaena hippurus from the SE Gulf of California, Mexico: Concentrations, biomagnification and dietary intake.

Mar Pollut Bull 2019 Jan 20;138:84-92. Epub 2018 Nov 20.

Universidad Nacional Autónoma de México, Instituto de Ciencias del Mar y Limnología, Unidad Académica Mazatlán, P.O. Box 811, C.P. 82000 Mazatlán, Sinaloa, Mexico; Miembro de El Colegio de Sinaloa, Antonio Rosales 435 Pte, Culiacán, Sinaloa, Mexico. Electronic address:

Selenium and mercury were evaluated in tissues and stomachs of the dolphinfish Coryphaena hippurus from two sites in the Southeastern Gulf of California. Hg levels were consistently low and exhibited the following patterns: muscle (0.14 ± 0. Read More

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http://dx.doi.org/10.1016/j.marpolbul.2018.11.023DOI Listing
January 2019

Microplastics do not increase toxicity of a hydrophobic organic chemical to marine plankton.

Mar Pollut Bull 2019 Jan 17;138:58-62. Epub 2018 Nov 17.

ECIMAT, Universidade de Vigo, Illa de Toralla, E-36331 Vigo, Galicia, Spain. Electronic address:

Planktonic sea-urchin larvae actively ingest polyethylene microplastics (MP) that accumulate in the larval stomach and can be distinguished from natural food using polarized light microscopy. MP filtering rates were similar to those of natural particles (microalgae) of the same size range; 0.30 to 0. Read More

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http://dx.doi.org/10.1016/j.marpolbul.2018.11.029DOI Listing
January 2019

First record of debris ingestion by the shorebird American Oystercatcher (Haematopus palliatus) on the Southern coast of Brazil.

Mar Pollut Bull 2019 Jan 26;138:235-240. Epub 2018 Nov 26.

Pós-graduação em Biologia - Universidade do Vale do Rio dos Sinos - UNISINOS, Avenida Unisinos, 950, Bairro Cristo Rei, São Leopoldo 93020-190, Rio Grande do Sul, Brazil. Electronic address:

Plastic has become abundant in the oceans and proved to be a threat to marine and coastal fauna. In this study, we present the first record of synthetic debris ingested by the shorebird American Oystercatcher (Haematopus palliatus) in Brazil. We collected 24 stomach contents from October 2007 to October 2015 and 58% were juveniles. Read More

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http://dx.doi.org/10.1016/j.marpolbul.2018.11.051DOI Listing
January 2019

Plastic ingestion in aquatic birds in Portugal.

Mar Pollut Bull 2019 Jan 16;138:19-24. Epub 2018 Nov 16.

Department of Zoology and Entomology, Rhods University, Grahamstown 6140, South Africa.

In modern society, plastic items have become indispensable. The rapid growth of plastic production has led to an increase in the concentration of plastic waste in the environment and, consequently, wildlife has been severely affected. As wide-ranging foragers and predators, aquatic birds are ideal sentinels for monitoring changes in their environment. Read More

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http://dx.doi.org/10.1016/j.marpolbul.2018.11.024DOI Listing
January 2019

Prenatal detection of esophageal atresia: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2019 Jan 19. Epub 2019 Jan 19.

Department of Specialist Neonatal and Pediatric Surgery, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.

Introduction: The primary aim of this systematic review was to quantify the diagnostic performance of ultrasound, MRI and amniotic fluid analysis in detecting esophageal atresia (EA) prenatally. The secondary aim was to explore the accuracy of individual imaging signs in identifying this anomaly.

Material And Methods: Medline, Embase and Cochrane databases were searched. Read More

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http://dx.doi.org/10.1111/aogs.13536DOI Listing
January 2019

Symptomatic involvement of the stomach and duodenum as initial presentation of AL amyloidosis.

BMJ Case Rep 2019 Jan 17;12(1). Epub 2019 Jan 17.

Cleveland Clinic Florida, Weston, Florida, USA.

Primary systemic or amyloid light chain (AL) amyloidosis is a multisystem disorder with myriad presentations. Although it can involve the upper gastrointestinal tract in 8% of cases, symptomatic involvement is exceedingly rare. We chronicle here a case of postprandial epigastric pain associated with AL amyloidosis involving the stomach and duodenum. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22755
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http://dx.doi.org/10.1136/bcr-2018-227550DOI Listing
January 2019
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Using a dynamic artificial digestive system to investigate heme iron nitrosylation during gastro-intestinal transit.

Food Chem 2019 May 2;281:231-235. Epub 2019 Jan 2.

INRA, UR370 Qualité des Produits Animaux, F-63122 Saint Genès-Champanelle, France. Electronic address:

The International Agency for Research on Cancer recently classified cured meats as carcinogenic for humans and red meats as probably carcinogenic. Mutagens can be formed during meat process or digestion. In a previous study, we used a dynamic artificial digestive system (DIDGI®) to investigate protein oxidation and N-nitrosation during bovine meat digestion. Read More

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http://dx.doi.org/10.1016/j.foodchem.2018.12.094DOI Listing

Endoscopic removal of two long iron rods impacted in the stomach.

Endoscopy 2019 Jan 18. Epub 2019 Jan 18.

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0824-6087
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http://dx.doi.org/10.1055/a-0824-6087DOI Listing
January 2019
3 Reads

Consumer trophic positions respond variably to seasonally fluctuating environments.

Ecology 2019 Jan 18:e02570. Epub 2019 Jan 18.

Department of Integrative Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada.

The effects of environmental seasonality on food web structure have been notoriously understudied in empirical ecology. Here, we focus on seasonal changes in one key attribute of a food web, consumer trophic position. We ask whether fishes inhabiting tropical river-floodplain ecosystems behave as seasonal omnivores, by shifting their trophic positions in relation to the annual flood pulse, or whether they feed at the same trophic position all year, as much empirical work implicitly assumes. Read More

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http://dx.doi.org/10.1002/ecy.2570DOI Listing
January 2019

A review on role of ATM gene in hereditary transfer of colorectal cancer.

Acta Biomed 2019 Jan 15;89(4):463-469. Epub 2019 Jan 15.

Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai-603103, India.

Colorectal cancer found to be the most commonly occurring cancer worldwide which can be prevented by screening and its curable if diagnosed early. Lynch syndrome/HNPCC being an autosomal genetic disease and propensity in forming colorectal cancer is inherited wherein genomic instabilities and epigenetic changes are being the characteristic forms in hereditary cancers. It is very important to determine the polymorphism in several DNA repairing genes such as ATM, RAD51, XRCC2, XRCC3 and XRCC9 to study the risk exploring both the prognosis and the developing of colorectal cancer. Read More

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http://www.mattioli1885journals.com/index.php/actabiomedica/
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http://dx.doi.org/10.23750/abm.v89i4.6095DOI Listing
January 2019
2 Reads

Pharmacokinetics of orally administered tramadol in Muscovy ducks (Cairina moschata domestica).

J Vet Pharmacol Ther 2019 Jan 17. Epub 2019 Jan 17.

The Chicago Zoological Society, Brookfield, Illinois.

This study documents the pharmacokinetics of oral tramadol in Muscovy ducks. Six ducks received a single 30 mg/kg dose of tramadol, orally by stomach tube, with blood collection prior to and up to 24 hr after tramadol administration. Plasma tramadol, and metabolites O-desmethyltramadol (M1), and N,O-didesmethyltramadol (M5) concentrations were determined by high-pressure liquid chromatography (HPLC) with fluorescence (FL) detection. Read More

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http://dx.doi.org/10.1111/jvp.12743DOI Listing
January 2019

Common Antacid Medication-Ranitidine Causing a Rare Serious Adverse Effect.

Cureus 2018 Nov 12;10(11):e3578. Epub 2018 Nov 12.

Gastroenterology, Hackensack University Palisades Medical Center, Lodi, USA.

Ranitidine is a widely used over-the-counter antacid medication, and is generally very well tolerated. To our knowledge, anaphylaxis secondary to ranitidine is exceedingly rare, and has only been reported in a few case reports. We present a patient who developed an anaphylactic reaction after one tablespoon of ranitidine. Read More

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http://dx.doi.org/10.7759/cureus.3578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333252PMC
November 2018

Glomus tumor of the stomach treated by laparoscopic distal gastrectomy: A case report.

Oncol Lett 2019 Jan 25;17(1):514-517. Epub 2018 Oct 25.

Department of Surgery, Kochi Medical School, Nankoku, Kochi 783-8505, Japan.

Glomus tumor of the stomach is a rare submucosal mesenchymal tumor. The present study reports a patient with gastric glomus tumor treated by laparoscopic distal gastrectomy. A 39-year-old male was referred to Kochi Medical School Hospital for examination of a gastric submucosal tumor (SMT) initially diagnosed following a medical check-up. Read More

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http://dx.doi.org/10.3892/ol.2018.9621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313179PMC
January 2019

Expression pattern and level of ING5 protein in normal and cancer tissues.

Oncol Lett 2019 Jan 16;17(1):63-68. Epub 2018 Oct 16.

Cancer Center and Key Laboratory of Brain and Spinal Cord Injury of Liaoning Province, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.

Inhibitor of growth family 5 (ING5) functions as a type-II tumor suppressor gene and exerts an important role in DNA repair, apoptotic induction, proliferative inhibition, chromatin remodeling and the invasion process. In the present study, immunohistochemistry was performed to characterize the expression profile of ING5 protein on a tissue microarray containing mouse and human normal tissues, and human cancer tissues, including hepatocellular (n=62), renal clear cell (n=62), pancreatic (n=62), esophageal squamous cell (n=45), cervical squamous cell (n=31), breast (n=144), gastric (n=196), colorectal (n=96), endometrial (n=96) and lung carcinoma (n=192). In the mouse tissues, ING5 expression was detected in the cytoplasm of neurons, the nephric tubule and glomerulus, alveolar epithelium, gastrointestinal glands, squamous epithelium of the skin and skeletal muscles. Read More

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http://dx.doi.org/10.3892/ol.2018.9581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313139PMC
January 2019

High expression of acidic chitinase and chitin digestibility in the stomach of common marmoset (Callithrix jacchus), an insectivorous nonhuman primate.

Sci Rep 2019 Jan 17;9(1):159. Epub 2019 Jan 17.

Department of Chemistry and Life Science, Kogakuin University, Hachioji, Tokyo, 192-0015, Japan.

Chitin is a polymer of N-acetyl-D-glucosamine (GlcNAc) and a main constituent of insects' exoskeleton. Insects are rich in protein with high energy conversion efficiency. Recently, we have reported that acidic chitinases (Chia) act as digestive enzymes in mouse, pig and chicken (omnivorous) but not in dog (carnivorous) and bovine (herbivorous), indicating that feeding behavior affects Chia expression levels, and determines chitin digestibility in the particular animals. Read More

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http://dx.doi.org/10.1038/s41598-018-36477-yDOI Listing
January 2019

Totally laparoscopic versus open gastrectomy for advanced gastric cancer: a matched retrospective cohort study.

Hong Kong Med J 2019 Jan 18. Epub 2019 Jan 18.

Department of Surgery, Queen Elizabeth Hospital, Jordan, Hong Kong.

Introduction: Laparoscopic gastrectomy revolutionised the management of gastric cancer, yet its oncologic equivalency and safety in treating advanced gastric cancer (especially that in smaller centres) has remained controversial because of the extensive lymphadenectomy and learning curve involved. This study aimed to compare outcomes following laparoscopic versus open gastrectomy for advanced gastric cancer at a regional institution in Hong Kong.

Methods: Fifty-four patients who underwent laparoscopic gastrectomy from January 2009 to March 2017 were compared with 167 patients who underwent open gastrectomy during the same period. Read More

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https://www.hkmj.org/earlyrelease/hkmj177150.html
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http://dx.doi.org/10.12809/hkmj177150DOI Listing
January 2019
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Cervical cutaneous sclerosis: the stomach is not far from the skin.

J Eur Acad Dermatol Venereol 2019 Jan 17. Epub 2019 Jan 17.

Department of Dermatology, Assistance Publique - Hôpitaux de Paris, Henri Mondor Hospital, Créteil, France.

Here in, we report a particular case presenting an erythematous and indurated plaque of the neck that has revealed gastric linitis plastic (GLP). An 80-year-old man presented to the Department of Dermatology in November 2015 with a 2-month history of a sclerotic inflammatory infiltration of the skin located on the anterior cervical region (Figure 1a, b) associated with a general impaired condition. Medical history revealed a partial gastrectomy for peptic ulcer 30 years ago. Read More

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http://doi.wiley.com/10.1111/jdv.15432
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http://dx.doi.org/10.1111/jdv.15432DOI Listing
January 2019
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Pediatric plexiform fibromyxoma: A PRISMA-compliant systematic literature review.

Medicine (Baltimore) 2019 Jan;98(3):e14186

Department of Pathology, National Hospital Organization Beppu Medical Center, 1473 Oaza-Uchikamado, Beppu, Oita, Japan.

Background: Plexiform fibromyxoma (PF) is a rare gastric mesenchymal tumor, with approximately 80 cases reported to date. Gastrointestinal stromal tumor, the most common primary mesenchymal tumor of the stomach, shows different biological and clinical characteristics between adult and pediatric patients.

Objectives: This systematic literature review was conducted to elucidate the pathological and clinical features of pediatric PF compared to adult PF. Read More

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http://dx.doi.org/10.1097/MD.0000000000014186DOI Listing
January 2019

A novel self-expanding biflanged metal stent vs tubular metal stent for EUS-guided transmural drainage of pancreatic pseudocyst: A retrospective, cohort study.

Medicine (Baltimore) 2019 Jan;98(3):e14179

Department of Gastroenterology, Changhai Hospital, Second Military Medical University.

Although endoscopic ultrasound (EUS)-guided transmural drainage of pancreatic fluid collections with metal stents is generally preferred over plastic stents, its superiority among different types of metal stents has not yet been well studied. We conducted this study to compare clinical outcomes and complications of a novel self-expanding biflanged metal stent (BFMS) and a traditional-shaped tubular metal stent (TMS) in treating pancreatic pseudocyst (PPC).This was a retrospective analysis on consecutive patients with PPC underwent EUS-guided transmural drainage with either TMS or BFMS in a single tertiary center with expertise in management of complex biliary and pancreatic problems. Read More

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http://dx.doi.org/10.1097/MD.0000000000014179DOI Listing
January 2019
1 Read

Seminal vesicle metastasis after liver transplantation for hepatocellular carcinoma: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e13770

Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing University, Medical School.

Rationale: Cancer recurrence and metastasis after liver transplantation (LT) is common in some hepatocellular carcinoma (HCC) patients. The most common sites of extrahepatic metastases are lung, regional lymph node, adrenal gland, and bone. To our knowledge, HCC metastasis to the seminal vesicle after LT has not been reported in the literature. Read More

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http://dx.doi.org/10.1097/MD.0000000000013770DOI Listing
January 2019

Endogenous glucocorticoids prevent gastric metaplasia by suppressing spontaneous inflammation.

J Clin Invest 2019 Jan 17. Epub 2019 Jan 17.

In the stomach, chronic inflammation causes metaplasia and creates a favorable environment for the evolution of gastric cancer. Glucocorticoids are steroid hormones that repress proinflammatory stimuli but their role in the stomach is unknown. In this study, we show that endogenous glucocorticoids are required to maintain gastric homeostasis. Read More

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http://dx.doi.org/10.1172/JCI123233DOI Listing
January 2019

Mesh migration into stomach following diaphragmatic hernia repair: a rare complication.

Pol Przegl Chir 2018 Aug;90(6):1-5

Jagjivan Ram Hospital Surgical Gastroenterology.

Mesh erosion and migration are considered the gravest of complications of mesh repairs. To the best of our knowledge, mesh erosion and migration into the stomach following a mesh repair of adult diaphragmatic hernia has yet to be reported in the literature. A case of mesh eroding into the stomach, after a prosthetic repair of an adult diaphragmatic hernia, is presented here because of its rarity. Read More

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https://ppch.pl/gicid/01.3001.0012.2634
Publisher Site
http://dx.doi.org/10.5604/01.3001.0012.2634DOI Listing
August 2018
1 Read

Deep Learning-Based Survival Analysis Identified Associations Between Molecular Subtype and Optimal Adjuvant Treatment of Patients With Gastric Cancer.

JCO Clin Cancer Inform 2018 Dec(2):1-14

Jeeyun Lee, Ji Yeong An, Min Gew Choi, Se Hoon Park, Seung Tae Kim, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Sung Kim, Hyuk Lee, Byung-Hoon Min, Jae J. Kim, Woo Kyoung Jeong, Dong-Il Choi, Kyoung-Mee Kim, Won Ki Kang, and Sung Wook Seo, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; and Mijung Kim, Ghent University, Ghent, Belgium.

Purpose: Gastric cancer (GC) is the third-leading cause of cancer-related deaths. Several pivotal clinical trials of adjuvant treatments were performed during the previous decade; however, the optimal regimen for adjuvant treatment of GC remains controversial.

Patients And Methods: We developed a novel deep learning-based survival model (survival recurrent network [SRN]) in patients with GC by including all available clinical and pathologic data and treatment regimens. Read More

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http://ascopubs.org/doi/10.1200/CCI.17.00065
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http://dx.doi.org/10.1200/CCI.17.00065DOI Listing
December 2018
3 Reads

Efficacy and Safety of Combination of NSAIDs and Muscle Relaxants in the Management of Acute Low Back Pain.

Pain Ther 2019 Jan 16. Epub 2019 Jan 16.

Global Medical Affairs, Dr Reddy's Laboratories Ltd, 8-2-337, Road No 3, Banjara Hills, Hyderabad, 500034, India.

Introduction: Low back pain is a common problem worldwide causing deterioration of health and quality of life. Low back pain is often associated with muscle spasm. We investigated the combined effect of muscle relaxants and pain killers for low back pain. Read More

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http://dx.doi.org/10.1007/s40122-019-0112-6DOI Listing
January 2019
2 Reads

Perioperative Mortality Does Not Explain Racial Disparities in Gastrointestinal Cancer.

J Gastrointest Surg 2019 Jan 16. Epub 2019 Jan 16.

Department of Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.

Background: Racial minorities with gastrointestinal cancer suffer disproportionately poor overall and disease-specific survival. We used a nationally representative sample to examine the relationship between race/ethnicity and mortality and determine whether these disparities were observed in the perioperative period.

Materials And Methods: The Nationwide Inpatient Sample (NIS) was used to examine patients undergoing surgery for cancers of the esophagus, stomach, pancreas, colon and rectum ("GI cancer") between 2008 and 2012. Read More

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http://dx.doi.org/10.1007/s11605-018-4064-7DOI Listing
January 2019

Isolated IgG4-related gastric disease presenting as diffuse gastric wall thickening with ulcer.

J Radiol Case Rep 2018 Sep 30;12(9):9-20. Epub 2018 Sep 30.

Department of Anatomical Pathology, Singapore General Hospital, Singapore.

An 81-year-old male presented with loss of appetite, early satiety and iron deficiency anaemia. A computed tomography (CT) scan of the abdomen and pelvis during initial work-up revealed diffuse gastric mural thickening associated with a large ulcer and adjacent gastro-hepatic lymphadenopathy. The CT appearances, together with the clinical features, were highly suspicious for an infiltrative type of gastric malignancy. Read More

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http://radiologycases.com/index.php/radiologycases/article/v
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http://dx.doi.org/10.3941/jrcr.v12i9.3493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312045PMC
September 2018
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Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m.

Pharmaceuticals (Basel) 2019 Jan 15;12(1). Epub 2019 Jan 15.

Department of Nuclear Medicine, Medical University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria.

The high overexpression of cholecystokinin-2 receptors (CCK2R) in tumors, such as medullary thyroid carcinoma, allows for highly specific diagnostic and therapeutic targeting with radiolabeled peptide probes derived from natural ligands for the receptor. Based on the ideal imaging characteristics, high availability and low cost of technetium-99m (Tc)-labeled radiopharmaceuticals we have developed two hydrazinonicotinic acid (HYNIC) conjugated minigastrin analogs allowing labeling at high specific activity. The CCK2R targeting peptide conjugates show specific amino acid substitutions in the C-terminal receptor-specific sequence with the aim to increase stability and tumor targeting. Read More

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http://www.mdpi.com/1424-8247/12/1/13
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http://dx.doi.org/10.3390/ph12010013DOI Listing
January 2019
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SMARCB1- and vimentin-positive esophageal carcinoma with undifferentiated components, rhabdoid features, and a good prognosis: a case report.

Surg Case Rep 2019 Jan 16;5(1). Epub 2019 Jan 16.

1st Department of Surgery, Faculty of Medicine, University of Fukui, 23-3 Matsuokashimoaizuki, Yoshida-gun, Eiheiji-cho, Fukui, 910-1193, Japan.

Background: Undifferentiated carcinoma of the esophagus with rhabdoid features is a very rare histologic finding that is occasionally associated with the loss of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1); however, until now, few survey reports of this type of tumor have been published. In this study, we describe a case of esophageal carcinoma with undifferentiated components and rhabdoid features that was exclusively positive for vimentin and SMARCB1 in a patient with prolonged survival.

Case Presentation: A 67-year-old man complained of a stomachache and loss of appetite persisting for 1 month. Read More

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https://surgicalcasereports.springeropen.com/articles/10.118
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http://dx.doi.org/10.1186/s40792-019-0562-4DOI Listing
January 2019
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Sealed endoscopic full-thickness resection for gastric cancer: a pilot study in an ex vivo and in vivo porcine model.

Endosc Int Open 2019 Jan 3;7(1):E36-E42. Epub 2019 Jan 3.

Department of Surgical Oncology, Kanazawa Medical University, Ishikawa, Japan.

Endoscopic full-thickness resection (EFTR) is a useful procedure that allows minimal resection of the gastric wall because the tumor can be located endoscopically. However, the procedure carries a risk of peritoneal infection or dissemination. Thus, we devised a new EFTR technique in which the serosa is sealed using a silicone sheet to prevent the escape of gastric juice. Read More

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http://dx.doi.org/10.1055/a-0777-1954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327734PMC
January 2019
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Emergency Presentation of Gastric Ectopic Pancreas.

Cureus 2018 Nov 8;10(11):e3565. Epub 2018 Nov 8.

Surgery, Papa Giovanni Xxiii Hospital, Bergamo, ITA.

Ectopic pancreas is a rare embryological abnormality apparently not in association with others. Stomach and duodenum are the most common organs involved. Symptoms are nonspecific. Read More

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https://www.cureus.com/articles/14601-emergency-presentation
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http://dx.doi.org/10.7759/cureus.3565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325026PMC
November 2018
4 Reads

Anaplastic Thyroid Carcinoma with Gastric Metastasis.

Curr Health Sci J 2018 Jul-Sep;44(3):294-298. Epub 2018 Jul 15.

Department of Gastroenterology, Hepatology, and Nutrition, University of Texas-MD Anderson Cancer Center, Houston, Texas, USA.

Introduction: Carcinomas of the thyroid gland represent 3% of all malignancies, with 1.3 to 9.8% corresponding to anaplastic thyroid carcinomas (ATC). Read More

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http://dx.doi.org/10.12865/CHSJ.44.03.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311218PMC
July 2018
2 Reads

Probiotic spp. act Against -induced Inflammation.

J Clin Med 2019 Jan 14;8(1). Epub 2019 Jan 14.

Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan 33302, Taiwan.

The bacterial species, , is associated with several gastrointestinal diseases, and poses serious health threats owing to its resistance to antibiotics. spp., on the other hand, possess probiotic activities that have beneficial effects in humans. Read More

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http://dx.doi.org/10.3390/jcm8010090DOI Listing
January 2019

The lipoprotein HP1454 of Helicobacter pylori regulates T cell response by shaping T Cell Receptor signalling.

Cell Microbiol 2019 Jan 15:e13006. Epub 2019 Jan 15.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Helicobacter pylori (HP) is a Gram-negative bacterium that chronically infects the stomach of more than 50% of human population and represents a major cause of gastric cancer, gastric lymphoma, gastric autoimmunity and peptic ulcer. It still remains to be elucidated which HP virulence factors are important in the development of gastric disorders. Here we analysed the role of the HP protein HP1454 in the host-pathogen interaction. Read More

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http://dx.doi.org/10.1111/cmi.13006DOI Listing
January 2019
4 Reads
4.915 Impact Factor

Dinorcassane diterpenoid from Boesenbergia rotunda rhizomes collected in Lower Myanmar.

Chem Biodivers 2019 Jan 15. Epub 2019 Jan 15.

University of Toyama, Institute of Natural Medicine, 2330-Sugitani, Not Available, 930-0194, Toyama, JAPAN.

A new dinorcassane diterpenoid, seikphoochinal A (1), and four known compounds, pinostrobin (2), 4',7-dimethylkaempferol (3), and galanals A (4) and B (5), were isolated from the chloroform-soluble crude extract of wild type Boesenbergia rotunda rhizomes collected in Lower Myanmar. The chemical structures of these compounds were identified, using a combination of spectroscopic methods. The presence of the diterpenoids 1, 4, and 5 demonstrated the structural diversity of wild type B. Read More

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http://dx.doi.org/10.1002/cbdv.201800657DOI Listing
January 2019

Gastric Angiomyolipoma Masquerading as Gastric Malignancy.

ACG Case Rep J 2018 19;5:e96. Epub 2018 Dec 19.

Department of Pathology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.

Gastric angiomyolipoma (AML) is extremely rare, with only 3 cases reported in English literature, all of which presented with upper gastrointestinal bleed, either in the form of hematemesis or melena. A 42-year-old man presented with upper gastrointestinal bleed, the source of which was found to be a large mass in the stomach, which was shown histologically to be gastric AML. This is the fourth but largest tumor (9 × 6 × 5 cm) to be reported to date. Read More

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http://dx.doi.org/10.14309/crj.2018.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317839PMC
December 2018

Unexplained Portal Gas in a Patient with an Esophageal Ulcer.

Case Rep Gastrointest Med 2018 10;2018:2496193. Epub 2018 Dec 10.

Sinai Hospital, Baltimore, Maryland, USA.

Emphysematous gastritis is the infection of gastric mucosa by gas producing microorganisms. It is a rare infection with less than 100 cases reported in the literature. The association of portal venous gas along with emphysematous gastritis is a rare entity. Read More

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http://dx.doi.org/10.1155/2018/2496193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311260PMC
December 2018
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Antioxidative and Anti-Inflammatory Effects of Water Extract of Linn. against Ethanol-Induced Gastric Ulcer in Rats.

Evid Based Complement Alternat Med 2018 12;2018:3585394. Epub 2018 Dec 12.

Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.

Linn., a medicinal pteridophyte growing in mangrove forests and coastal regions of tropical and subtropical areas worldwide, has been proved to possess various biological effects. However, the protective effect of Linn. Read More

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http://dx.doi.org/10.1155/2018/3585394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311278PMC
December 2018