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Genes Chromosomes Cancer 2020 Jun 5. Epub 2020 Jun 5.

Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany.

Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal tumors of the gastrointestinal tract. Inactivating mutations or epigenetic deregulation of succinate dehydrogenase complex (SDH) genes are considered defining features of a subset of GIST occurring in the stomach. Based on comprehensive molecular profiling and biochemical analysis within a precision oncology program, we identified hallmarks of SDH deficiency (germline SDHB-inactivating mutation accompanied by somatic loss of heterozygosity, lack of SDHB expression, global DNA hypermethylation, elevated succinate/fumarate ratio) in a 40-year-old woman with undifferentiated gastric spindle cell sarcoma that did not meet diagnostic criteria for other mesenchymal tumors of the stomach, including GIST. Read More

Expert Rev Gastroenterol Hepatol 2020 Jun 5. Epub 2020 Jun 5.

Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo , Tokyo, Japan.

Introduction Artificial intelligence (AI) that surpasses human ability in image recognition is expected to be applied in the field of gastrointestinal endoscopes. Accordingly, its research and development (R &D) is being actively conducted. With the development of endoscopic diagnosis, there is a shortage of specialists who can perform high-precision endoscopy. Read More

J Radiat Res 2020 Jun 5. Epub 2020 Jun 5.

International Research Institute of Disaster Science (IRIDeS), Tohoku University, Aramaki Aza-Aoba 468-1, Aoba-ku, Sendai 980-8572, Japan.

The aim of this study was to determine parameters for estimating the internal exposure of all organs in mouse experiments from the radioactivity concentration in organs. The estimation of internal exposure rate conversion coefficients and absorbed fractions for 137Cs, 134Cs and 90Sr by the Particle and Heavy Ion Transport code System (PHITS) with a voxel-based mouse phantom is presented. The geometry of the voxel phantom is constructed from computer tomography images of a mouse 9 cm in length weighing 23. Read More

Cureus 2020 May 3;12(5):e7941. Epub 2020 May 3.

Medicine, Imperial College London, London, GBR.

Ghrelin is a peptide hormone that is primarily released from the stomach. It is best known for its role in appetite initiation. However, evidence also suggests that ghrelin may play a much wider role in energy homeostasis and glucose metabolism. Read More

Diagn Pathol 2020 Jun 4;15(1):69. Epub 2020 Jun 4.

Department of Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

Background: The prognostic potential of PD-L1 is currently unclear in gastric carcinomas, although the immune checkpoint PD-1/PD-L1 inhibitors have produced promising results in clinical trials.

Methods: We explored the prognostic implications of programmed death ligand 1 (PD-L1) in 514 consecutive surgically-resected gastric carcinomas. Overall survival and recurrence-free survival were evaluated. Read More

Foods 2020 Jun 2;9(6). Epub 2020 Jun 2.

Laboratory of Pathology, Instituto Nacional Cardiovascular, Jirón Coronel Zegarra 417, Jesús María 15072, Peru.

Potato tocosh is a naturally processed potato for nutritional and curative purposes from traditional Peruvian medicine. The aim of this study was to investigate the acute and sub-acute toxicity of tocosh flour (TF). For sub-acute toxicity, TF was administered orally to rats daily once a day for 28 days at doses of 1000 mg/kg body weight (BW). Read More

Int J Environ Res Public Health 2020 Jun 2;17(11). Epub 2020 Jun 2.

Department of Neurology and Stroke Center, University Hospital Mizonokuchi, Teikyo University School of Medicine, 5-1-1, Futago, Takatsu-ku, Kawasaki, Kanagawa 213-8507, Japan.

Suppression of risk factors including smoking, overdrinking and infections by human papilloma and hepatitis B and C viruses has been recommended for cancer prevention; however, identification of other environmental risk factors has not been enough. Besides the 2003 report that Kawasaki disease may be triggered by pollen exposure, 40 Japanese specific intractable diseases have recently been reported as "pollen diseases," also potentially triggered by pollen exposure．Various human organs are affected by pollen exposure, leading to systemic vasculitis; autoimmune connective tissue diseases, inflammatory bowel diseases and intractable neuromuscular and bone diseases, suggesting the common effects of pollen exposure on fundamental functions of vital metabolism. In this context, cancer and malignant tumors may be another group of intractable diseases triggered by epigenetic pollen exposure. Read More

Microorganisms 2020 Jun 2;8(6). Epub 2020 Jun 2.

Laboratory of Gastroenterology, Research Institute of Internal and Preventive Medicine-Branch of The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of Russian Academy of Sciences, Novosibirsk 630089, Russia.

Gallstone disease (GSD) has, for many years, remained a high-cost, socially significant public health problem. Over the past decade, a number of studies have been carried out-both in humans and in animal models-confirming the role of the microbiota in various sections of the gastrointestinal tract as a new link in the etiopathogenesis of GSD. The microbiome of bile correlates with the bacterial composition of saliva, and the microbiome of the biliary tract has a high similarity with the microbiota of the duodenum. Read More

J Int Med Res 2020 Jun;48(6):300060520925941

Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Objective: To investigate the impact of enhanced recovery after surgery (ERAS) on the postoperative neutrophil-lymphocyte ratio (NLR) in patients with colorectal cancer.

Methods: A total of 200 patients with colorectal cancer who underwent surgery between January 2015 and November 2018 were enrolled in the study. They were divided into a traditional treatment group (n=100) and an ERAS group (n=100). Read More

Zhongguo Zhong Yao Za Zhi 2020 May;45(10):2329-2334

the PLA Navy General Hospital Beijing 100048, China.

To analyzed the actual clinical application of Xingnaojing Injection in treating cerebral infarction in the real world, selected HIS(hospital information system) database of inpatients in 39 hospitals across the country, and conducted descriptive analysis and association rule analysis on the information of 11 674 patients with cerebral infarction using Xingnaojing Injection. The results showed that the average age of the patients was 69.69 years. Read More

Zhongguo Zhong Yao Za Zhi 2020 May;45(10):2316-2321

School of Statistics, Renmin University of China Beijing 100872, China.

From January 1, 2004 to July 21, 2016 a total of 2 796 cases of adverse drug reaction/adverse event(ADR/AE) after the use of Xianling Gubao Capsules/Tablets were reported by National Adverse Drug Reaction Monitoring Center. The following results were obtained by analyzing the reports of 2 796 cases of adverse drug reactions/adverse drug events after the use of Xianling Gubao Capsules/Tablets. A total of 75 patients, accounting for 2. Read More

Zhongguo Zhong Yao Za Zhi 2020 May;45(10):2257-2264

China Academy of Chinese Medical Sciences Beijing 100700, China.

There is urgent need to discover effective traditional Chinese medicine(TCM) for treating coronavirus disease 2019(COVID-19). The development of a bioinformatic tool is beneficial to predict the efficacy of TCM against COVID-19. Here we deve-loped a prediction platform TCMATCOV to predict the efficacy of the anti-coronavirus pneumonia effect of TCM, based on the interaction network imitating the disease network of COVID-19. Read More

Zhongguo Zhong Yao Za Zhi 2020 May;45(9):2144-2150

School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University Zhongshan 528458, China.

The aim of this paper was to investigate the effect of Huoxiang Zhengqi Oral Liquid on intestinal barrier functions in rats with dampness obstructing spleen-stomach syndrome and primarily explore the mechanism. The rat model of dampness obstructing spleen-stomach syndrome was established, and then the modeled rats were randomly divided into the model control group, Huoxiang Zhengqi Oral Liquid high and low dose groups, and natural recovery group according to gender and body weight, with 10 rats in each group. Another 10 rats were taken as blank control group. Read More

Dig Dis Sci 2020 Jun 3. Epub 2020 Jun 3.

Division of Gastroenterology, Portland VA Medical Center and Oregon Health & Science University, P3-GI, Portland, OR, 97239, USA.

Background And Aims: The causes for the occurrence of goblet cells at the gastroesophageal junction (GEJ-GC) are unknown. The aim of our study was to compare the concurrent histologic changes of the stomach in (1) patients with GEJ-GC, but without Barrett's esophagus (BE) to those in (2) patients with BE and in (3) controls without GEJ-GC or BE.

Methods: We used an electronic database of histopathologic records from 1. Read More

Surg Case Rep 2020 Jun 3;6(1):127. Epub 2020 Jun 3.

Department of Surgery, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-Minamimachi, Chuo-ku, Kobe, 650-0047, Japan.

Background: Colostomy via the intraperitoneal route is often performed during laparoscopic Hartmann's operation or abdominoperineal resection. Internal hernia of the small intestine often occurs after colostomy. This report shows a rare case of internal hernia of the stomach associated with sigmoid colostomy after laparoscopic abdominoperineal resection for rectal cancer. Read More

Int J Clin Oncol 2020 Jun 3. Epub 2020 Jun 3.

Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, Suita, Japan.

Background: We previously reported the HERBIS-4A phase II trial comparing S-1 plus cisplatin (SP) with capecitabine plus cisplatin (XP) in chemotherapy-naïve patients with HER2-negative advanced gastric cancer (GC). We performed a pooled analysis of HERBIS-4A and HERBIS-2, the phase II trial comparing SP with XP in HER2-negative recurrent GC patients with a recurrence-free interval after S-1 adjuvant therapy of ≥ 6 months.

Patients And Methods: Patients were randomly assigned to receive either SP [S-1 (40-60 mg twice daily for 21 days) plus cisplatin (60 mg/m on day 8), every 5 weeks] or XP [capecitabine (1000 mg/m twice daily for 14 days) plus cisplatin (80 mg/m on day 1), every 3 weeks]. Read More

Surg Case Rep 2020 Jun 3;6(1):126. Epub 2020 Jun 3.

Department of Surgery, Obihiro Kosei General Hospital, West 14 South 10, Obihiro, Hokkaido, 080-0024, Japan.

Background: Pancreatoduodenectomy with resection of the portal vein or superior mesenteric vein confluence has been safely performed in patients with pancreatic head cancer associated with infiltration of the portal vein or superior mesenteric vein. In recent years, left-sided portal hypertension, a late postoperative complication, has received focus owing to increased long-term survival with advances in chemotherapy. Left-sided hypertension may sometimes cause fatal gastrointestinal bleeding because of the rupture of gastrointestinal varices. Read More

Cureus 2020 May 1;12(5):e7909. Epub 2020 May 1.

Medical Gastroenterology, Mathura Das Mathur Hospital, Jodhpur, IND.

Corrosive-induced stricture of the digestive tract is a dreaded complication following corrosive ingestion. When surgical reconstruction is needed, esophagectomy helps to avoid the long-term complications related to leaving behind the scarred native esophagus. We tried to ascertain the feasibility and safety of a thoracolaparoscopic-assisted esophagectomy in such a setting. Read More

J Surg Case Rep 2020 May 26;2020(5):rjaa096. Epub 2020 May 26.

Department of pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Mass deworming against soil-transmitted helminthiasis, including (AL), is one of the largest public health interventions in low- and middle-income countries. The prevalence of in Tanzania is 6.8%. Read More

Infect Drug Resist 2020 13;13:1411-1417. Epub 2020 May 13.

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: Roles and incidence of some microorganisms that transiently or permanently colonize the human stomach are still unknown despite advances in gastroenterology. We aimed to examine the incidence of four microorganisms, , and , in the antral biopsy specimens of patients with gastroduodenal conditions.

Patients And Methods: Patients (67 females, 33 males; mean age = 49. Read More

BMC Biol 2020 Jun 4;18(1):55. Epub 2020 Jun 4.

Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 1088639, Japan.

Background: Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans. Comparing to bacteria, the viral component of the microbiome (i. Read More

Am J Physiol Regul Integr Comp Physiol 2020 Jun 3. Epub 2020 Jun 3.

Johns Hopkins Center for Neurogastroenterology, United States.

Background: Electroacupuncture (EA) is widely used as an effective method to treat stress-related disorders. However, its mechanisms remain largely unknown. The aim of this study was to investigate the effects and mechanisms of EA on gastric slow wave dysrhythmia and c-Fos expression in the nucleus tractus solitarius (NTS) induced by stress in a rodent model of functional dyspepsia (FD). Read More

Ann Pharmacother 2020 Jun 4:1060028020932521. Epub 2020 Jun 4.

Regis University School of Pharmacy, Denver, CO, USA.

To review the pharmacology, microbiology, efficacy, and safety of lefamulin. A literature search was performed using PubMed and Google Scholar (2010 to end-April 2020) with the search terms and . Other resources included abstracts presented at recent conferences, prescribing information, and the manufacturer's and Food and Drug Administration websites. Read More

J Clin Med 2020 Jun 1;9(6). Epub 2020 Jun 1.

Department of Gastroenterology and digestive oncology, Cochin Teaching Hospital, AP-HP, 75014 Paris, France.

The 2017 World Health Organization (WHO) classification of neuroendocrine neoplasms (NEN) of the digestive tract introduced a new category of tumors named well-differentiated grade 3 neuroendocrine tumors (NET G-3). These lesions show a number of mitosis, or a Ki-67 index higher than 20% with a well-differentiated morphology, therefore separating them from neuroendocrine carcinomas (NEC) which are poorly differentiated. It has become clear that NET G-3 show differences not only in morphology but also in genotype, clinical presentation, and treatment response. Read More

Foods 2020 Jun 1;9(6). Epub 2020 Jun 1.

SGIT-INIA, Tecnología de los Alimentos, Ctra. de la Coruña Km 7, 28040 Madrid, Spain.

Overweight and obesity are regarded as world epidemics and are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases, and cancer. Two new highly palatable extruded mixes based on rice and pea () or kidney bean () meals were incorporated into normocaloric or obesogenic diets for rats at a low inclusion level (25%). Our purpose was to evaluate the effects of dietary incorporation of this new food ingredient on lipid profile. Read More

Mar Drugs 2020 Jun 1;18(6). Epub 2020 Jun 1.

Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kyoto 6068502, Japan.

Siphonaxanthin has been known to possess inhibitory effects against obesity, inflammation, and angiogenesis. However, little information on its in vivo bioavailability and biotransformation is available. To assess the bioavailability and metabolism of siphonaxanthin, its absorption and accumulation were evaluated using intestinal Caco-2 cells and Institute of Cancer Research (ICR) mice. Read More

Int J Surg Case Rep 2020 May 25;71:315-318. Epub 2020 May 25.

General Surgery Department, San Salvatore Hospital, Paternò, Catania, Italy.

Introduction: Bouveret's syndrome is a rare complication of cholelithiasis that determines an unusual type of gallstone ileus, secondary to an acquired fistula between the gallbladder and either the duodenum or stomach with impaction of a large gallbladder stone. Preoperative diagnosis is difficult because of its rarity and the absence of typical symptoms. Adequate treatment consists of endoscopic or surgical removal of obstructive stone. Read More

J Ethnopharmacol 2020 May 31:112946. Epub 2020 May 31.

Department of Pharmacology, Zunyi Medical University, Zhuhai Campus, Zhuhai, 519041, PR China. Electronic address:

Ethnopharmacological Relevance: Zanthoxylum nitidum (Roxb.) DC. (Z. Read More

Physiol Biochem Zool 2020 Jul/Aug;93(4):320-338

The American alligator, , is an opportunistic carnivore that experiences an ontogenetic shift in food and feeding habits with an increase in body size. Alligators frequently feed on invertebrates and small fish as neonates and transition to feeding less frequently on larger vertebrates as they grow. We hypothesized that alligators experience an ontogenetic shift in the regulation of intestinal performance-modest regulation with frequent feeding early in life and wider regulation with less frequent feeding as they increase in body size. Read More

Br J Surg 2020 Jun 3. Epub 2020 Jun 3.

Centre for Gastric Cancer.

Background: Sentinel node navigation surgery reduces the extent of gastric and lymph node dissection, and may improve quality of life. The benefit and harm of laparoscopic sentinel node navigation surgery (LSNNS) for early gastric cancer is unknown. The SENORITA (SEntinel Node ORIented Tailored Approach) trial investigated the pathological and surgical outcomes of LSNNS compared with laparoscopic standard gastrectomy (LSG) with lymph node dissection. Read More

Braz J Biol 2020 May 29. Epub 2020 May 29.

Centro de Pesquisa de Limnologia, Biodiversidade e Etnobiologia do Pantanal, Universidade do Estado de Mato Grosso, Cáceres, MT, Brasil.

The composition of the diet of two species of characids (Knodus heteresthes and Moenkhausia lepidura) was evaluated in the Teles Pires and Juruena Rivers, sampled in September and October 2016. We analyzed 226 stomachs of K. heteresthes and 425 of M. Read More

Braz J Biol 2020 May 20. Epub 2020 May 20.

Departamento de Ciências Biológicas, Universidade Estadual do Sudoeste da Bahia, Jequié, BA, Brasil.

Phyllodytes tuberculosus is a bromeligenous anuran species whose geographic distribution is restricted to areas of the Caatinga and to transition zones between Caatinga and Atlantic Forest in the central-south of the state of Bahia. Its existence in close relationship with bromeliads and its occurrence in dry and highly seasonal environments drove us to the supposition that species is opportunistic/generalist regard to diet. We collected the items present in the stomach of 43 P. Read More

Environ Sci Technol 2020 Jun 3. Epub 2020 Jun 3.

We investigated the potential effects of different land use and other environment factors on animals living in a contaminated environment. The study site in Kabwe, Zambia, is currently undergoing urban expansion, while lead contamination from former mining activities is still prevalent. We focused on a habitat-generalist lizards (Trachylepis wahlbergii). Read More

Respir Med Case Rep 2020 23;30:101104. Epub 2020 May 23.

Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Most metastatic lung tumors display well-defined, round, multiple nodular shadows, whereas the presence of diffuse ground-glass opacities on chest computed tomography generally suggests non-malignant conditions. Here, we report an unusual case of pulmonary metastasis from gastric cancer in which diffuse ground-glass opacities were observed in all lung segments. A 59-year-old man with a 3-month history of worsening chest pain and shortness of breath was referred to the pulmonary clinic. Read More

Iran J Parasitol 2020 Jan-Mar;15(1):138-141

Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Qinghai University, Xining, Qinghai 810001, P.R.China.

There is no direct evidence to support the existence of regional lymph node metastatic routes in hepatic alveolar echinococcosis, and only a few literature have been reported. There was a case of hepatic alveolar echinococcosis suspected of metastasis of regional lymph node in Clinical Center for Hydatidosis, Qinghai Province, China. The patient was a 24-yr-old male from pastoral area of Seda County, Sichuan Province, China in 2018. Read More

Zhongguo Zhong Yao Za Zhi 2020 Apr;45(8):1942-1947

Child Care Centre, Affiliated Hospital of Changchun University of Chinese Medicine Changchun 130021, China.

To analyze and summarize formulae of traditional Chinese medicine(TCM) in the treatment of pediatric pneumonia in CNKI based on the data mining method. CNKI was retrieved for literatures of TCM treatment of pneumonia in children in recent 20 years, which was taken the data source. After screening, a prescription database was established. Read More

Zhongguo Zhong Yao Za Zhi 2020 Apr;45(7):1691-1697

Department of Spleen and Stomach, Hebei Hospital of Traditional Chinese Medicine Shijiazhuang 050011, China.

To explore the etiology, pathogenesis, distribution of syndromes and the rule of medication of chronic atrophic gastritis(CAG) in Beijing-Tianjin-Hebei region based on the latent structure model. Chronic atrophic gastritis of 279 cases in Beijing-Tianjin-Hebei region were extracted from the established database of spleen and stomach diseases of famous veteran Chinese medicine experts. The latent structure models of symptoms and drugs of chronic atrophic gastritis were constructed by using Lantern 3. Read More

Clin Transl Oncol 2020 Jun 1. Epub 2020 Jun 1.

Department of Gastroenterology, Infectious Diseases and Rheumatology. Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Germany.

Introduction: The tight junction molecule Claudin 18.2 is selectively expressed in healthy and malignant gastric epithelial tissue and is a promising therapy target for high Claudin 18.2 expressing adenocarcinomas of the esophagogastric junction and stomach (AEG/S). Read More

Surg Case Rep 2020 Jun 1;6(1):123. Epub 2020 Jun 1.

Department of Surgery, The Jikei University School of Medicine, 3-19-18 Nishi-shinbashi, Minato-ku, Tokyo, 105-8471, Japan.

Background: We encountered a case of marginal ulcer in the jejunum after distal gastrectomy with jejunal pouch interposition. However, it has not been reported and not confirmed the treatment. We chose truncal vagotomy, considering reduced morbidity and postoperative complications. Read More

Ann Surg Oncol 2020 Jun 2. Epub 2020 Jun 2.

Department of Surgery, University of Florida College of Medicine, Jacksonville, FL, USA.

The increasing prevalence of morbid obesity in the United States has been accompanied by a concomitant rise in bariatric surgery to help combat the epidemic. The relationship between obesity and certain cancers, such as esophageal adenocarcinoma, is well established. The need for minimally invasive techniques to treat esophageal cancer in patients with previous bariatric surgery is growing and can present a unique surgical challenge. Read More

Sci Rep 2020 Jun 2;10(1):8927. Epub 2020 Jun 2.

Institute of Aquaculture, Faculty of Natural Science, University of Stirling, FK9 4LA, Stirling, Scotland, UK.

Ensuring lumpfish health and welfare in salmon farms is vital to reduce the high mortality rates reported and to guarantee a high delousing efficiency. Recent observations of farmed lumpfish livers have shown colours ranging from pale (colours 1 and 2), through bright orange (colours 3 and 4), to dark reddish-brown (colours 5 and 6), some of which may be related to welfare condition. To characterize the status of lumpfish deployed in four Faroese salmon farms, several welfare indicators were assessed: a weight-length relationship, scoring of external physical damage, and after dissection, stomach content and liver colour scoring. Read More

Curr Opin Gastroenterol 2020 Jul;36(4):336-343

Institute of Esophageal and Reflux Surgery, Englewood, Colorado, USA.

Purpose Of Review: Precision treatment of medically-refractory regurgitation differs from that of heartburn. Regurgitation is an often-overlooked symptom characterized as a bitter taste in the mouth or a sense of fluid moving up from the stomach occurring in approximately 80% of gastroesophageal reflux disease (GERD) patients with varying severity. Its response to standard medical therapy is significantly less than heartburn while significantly lessening quality of life in 10-20% of GERD patients. Read More

Anticancer Res 2020 Jun;40(6):3401-3410

Department of Surgery, Sant' Andrea Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.

Background/aim: In local staging of gastric adenocarcinoma CT is the modality of choice. Less frequently used in a few selected patients is echo-endoscopy. Aim of this study was to evaluate the accuracy of hydro-multidetector-computed tomography (hydro-MDCT) in the evaluation of gastric adenocarcinomas with subsequent surgical and histopathological correlation to select cases for echo-endoscopy. Read More

Anticancer Res 2020 Jun;40(6):3203-3208

Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Republic of Korea

Background/aim: We aimed to evaluate the characteristics of gastric carcinoma with high excision repair cross complementing 1 (ERCC1) expression and the prognostic value of ERCC1 expression.

Materials And Methods: ERCC1 expression was evaluated by immunohistochemistry in 309 surgically resected gastric carcinoma specimens using a tissue microarray. Cancer-related survival was analysed using competing risk analysis. Read More

Diagn Pathol 2020 Jun 2;15(1):66. Epub 2020 Jun 2.

Department of Pathology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, PR China.

Background: Undifferentiated carcinomas of the gallbladder are extremely rare. Most undifferentiated carcinomas are accompanied by adjacent foci of other conventional carcinomas, and a transition zone is shared between them. However, genetic alterations of undifferentiated gallbladder carcinoma and the similarities or differences between the undifferentiated carcinoma and the foci conventional carcinoma are unknown. Read More

BMC Cancer 2020 Jun 2;20(1):490. Epub 2020 Jun 2.

Department of Gastroenterology, Jing'An District Centre Hospital of Shanghai (Huashan Hospital Fudan University Jing'An Branch), Shanghai, 200040, People's Republic of China.

Background: Stomach cancer (SC) is a type of cancer, which is derived from the stomach mucous membrane. As there are non-specific symptoms or no noticeable symptoms observed at the early stage, newly diagnosed SC cases usually reach an advanced stage and are thus difficult to cure. Therefore, in this study, we aimed to develop an integrated database of SC. Read More

World J Emerg Surg 2020 Jun 1;15(1):37. Epub 2020 Jun 1.

Unit of General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari "A. Moro", Polyclinic of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy.

Background: Giant hiatal hernia (GHH) is a condition where one-third of the stomach migrates into the thorax. Nowadays, laparoscopic treatment gives excellent postoperative outcomes. Strangulated GHH is rare, and its emergent repair is associated with significant morbidity and mortality rates. Read More