262 results match your criteria Stewart-Treves Syndrome

Stewart-Treves Syndrome in the Lower Limb after Arthroplasty- A Case Report.

Indian Dermatol Online J 2022 Mar-Apr;13(2):270-271. Epub 2022 Mar 3.

Department of Radiodiagnosis, Dr. Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.

Stewart-Treves Syndrome is a rare and fatal condition where cutaneous angiosarcoma-a high-grade malignant tumor originating in the vascular and lymphatic endothelium-classically develops in the upper limbs post-mastectomy, with radiation therapy and axillary lymph node dissection. There are very few reports of the syndrome developing in the lower limbs, without any preceding malignancy or radiation therapy. The median development time is 11 years. Read More

View Article and Full-Text PDF

Stewart-Treves syndrome in an older woman successfully treated by metronomic chemotherapy: case report and literature survey.

Anticancer Drugs 2022 02;33(2):220-224

Medical Oncology, Groupe Santé CHC Liège (B).

The authors present the case of a 94-year-old woman suffering from a right arm angiosarcoma developed after primary breast cancer and treated with success by oral metronomic chemotherapy based on daily low doses of cyclophosphamide and prednisone. The case description is followed by a short review of actual knowledge on the subject. Read More

View Article and Full-Text PDF
February 2022

Improvement of Stewart-Treves angiosarcoma through interleukin 23p19 inhibition.

JAAD Case Rep 2021 Nov 5;17:84-86. Epub 2021 Oct 5.

Department of Dermatology, Grand Hôpital de Charleroi, Charleroi, Belgium.

View Article and Full-Text PDF
November 2021

Stewart-Treves Syndrome in Obesity-Associated Chronic Lymphedema: A Case Report.

J Med Cases 2021 Oct 29;12(10):395-399. Epub 2021 Sep 29.

Department of Internal Medicine, Northwestern Medicine McHenry Hospital, McHenry, IL, USA.

Stewart-Treves syndrome (STS) is defined as the development of cutaneous angiosarcoma in the presence of long-standing lymphedema and is a rare disease with only about 400 cases reported in world literature. We report a case of a 63-year-old morbidly obese woman with a long-standing history of lymphedema who developed angiosarcoma of the right lower extremity with metastasis and presented with acute respiratory distress. The patient underwent a thorough laboratory workup with a chest X-ray showing bilateral effusions. Read More

View Article and Full-Text PDF
October 2021

Stewart-Treves Syndrome: A Rare But Aggressive Complication of Breast Cancer-Related Lymphedema.

Eur J Breast Health 2021 Oct 4;17(4):378-382. Epub 2021 Oct 4.

Department of Pathology, University of Hacettepe Faculty of Medicine, Ankara, Turkey.

Stewart-Treves syndrome (STS) is an angiosarcoma that usually develop in an extremity with longstanding lymphedema. Most affected patients have a history of breast cancer treated with radical mastectomy. Here, we report a case of STS with breast cancer-related lymphedema (BCRL) for a period of seven years. Read More

View Article and Full-Text PDF
October 2021

Stewart-Treves syndrome and other cutaneous malignancies in the context of chronic lymphedema: a systematic review.

Int J Dermatol 2022 Jan 1;61(1):62-70. Epub 2021 Jul 1.

Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Introduction: Angiosarcoma developing in chronically lymphedematous tissue, or Stewart-Treves syndrome (STS), is a rare and lethal complication of lymphedema. This systematic review summarizes characteristics and outcomes of STS and other cutaneous malignancies arising in chronic lymphedema.

Methods: MEDLINE and EMBASE databases were searched on February 19th, 2021, to identify 200 articles included in the analysis. Read More

View Article and Full-Text PDF
January 2022

[Stewart-Treves syndrome].

Rev Prat 2021 Jan;71(1):69

"Service de dermatologie et vénéréologie. CHU Ibn-Rochd, Casablanca, Maroc".

View Article and Full-Text PDF
January 2021

Stewart-Treves syndrome associated with disuse edema in amyotrophic lateral sclerosis.

J Dermatol 2021 Sep 31;48(9):e443-e444. Epub 2021 May 31.

Department of Dermatology, St. Marianna University School of Medicine, Kawasaki, Japan.

View Article and Full-Text PDF
September 2021

Stewart-Treves Syndrome.

JAMA Dermatol 2021 06;157(6):721

Dermatology Department, Instituto Valenciano de Oncología, Valencia, Spain.

View Article and Full-Text PDF

A case of Stewart-Treves Syndrome in a prostatectomized patient.

Ital J Dermatol Venerol 2021 Oct 23;156(5):633-634. Epub 2021 Apr 23.

Section of Dermatology, Venereology, Department of Medical, Surgical Sciences and Neurosciences, "Le Scotte" Polyclinic, University of Siena, Siena, Italy.

View Article and Full-Text PDF
October 2021

Stewart-Treves syndrome: a diagnosis to keep in mind.

Dermatol Online J 2021 Mar 15;27(3). Epub 2021 Mar 15.

1Department of Dermatology, Hospital de Santarém EPE, Santarém.

View Article and Full-Text PDF

Stewart-Treves Syndrome as a Rare and Fatal Complication of Post-Traumatic Lymphedema on the Lower Extremity.

Dermatol Pract Concept 2021 Mar 8;11(2):e2021004. Epub 2021 Mar 8.

Hospital São Lucas da PUCRS, Porto Alegre, Brazil.

View Article and Full-Text PDF

Stewart-Treves syndrome: Case report and literature review.

Rep Pract Oncol Radiother 2020 Nov-Dec;25(6):934-938. Epub 2020 Oct 1.

Department of Oncology and Radiotherapy, Charles University in Prague, Faculty of Medicine and University Hospital in Pilsen, alej Svobody 80, 304 60 Pilsen, Czech Republic.

Lymphangiosarcoma, or Stewart-Treves Syndrome (STS), is a very rare skin angiosarcoma with poor prognosis, which usually affects the upper limbs of patients who underwent breast cancer surgery, including axillary dissection followed by radiotherapy (RT). Cutaneous lymphangiosarcomas, which account for approximately 5% of all angiosarcomas, usually originate in the limb with chronic lymphedema. Lymphatic blockade is involved in the onset of STS. Read More

View Article and Full-Text PDF
October 2020

Stewart-Treves syndrome: a rapidly fatal complication of breast cancer treatment.

Lancet Oncol 2020 10;21(10):e495

Division of Hematology/Oncology, Warren Alpert Medical School at Brown University, Providence, RI, USA.

View Article and Full-Text PDF
October 2020

A case of Stewart-Treves syndrome occurring in the abdominal wall successfully treated with eribulin: A case report.

Mol Clin Oncol 2020 Nov 20;13(5):49. Epub 2020 Aug 20.

Musculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.

Angiosarcoma (AS) is a rare and aggressive tumor with high rates of local recurrence and distant metastasis. Stewart-Treves syndrome (STS) is defined as AS arising in the setting of chronic lymphedema, and is extremely uncommon in the lower abdominal wall. Eribulin mesylate (eribulin) is a non-taxane microtubule inhibitor that has been approved in Japan for treating soft tissue sarcoma. Read More

View Article and Full-Text PDF
November 2020

IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation.

Case Rep Oncol 2020 Jan-Apr;13(1):462-467. Epub 2020 Apr 30.

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17. Read More

View Article and Full-Text PDF

Effectiveness of pazopanib for local and lung metastases in Stewart-Treves syndrome.

Eur J Dermatol 2020 Feb;30(1):68-69

Department of Dermatology, Graduate School of Medicine and Pharmaceutical Sciences University of Toyama, Sugitani 2630, Toyama 930-0194, Japan.

View Article and Full-Text PDF
February 2020

Angiosarcoma arising in massive localized lymphedema.

Skeletal Radiol 2020 May 16;49(5):815-818. Epub 2020 Jan 16.

University of Missouri, 1 Hospital Dr, Columbia, MO, 65212, USA.

We report a case of a 70-year-old woman with a BMI of 58 who developed cellulitis refractory to treatment, within an area of massive localized lymphedema. Biopsy showed angiosarcoma. MRI showed multiple lobulated, low T1, high T2 masses within a background of prominent soft tissue septal stranding, dilated lymphatic channels, and skin thickening. Read More

View Article and Full-Text PDF

Clinicopathologic features of Stewart-Treves syndrome.

Int J Clin Exp Pathol 2019 1;12(3):680-688. Epub 2019 Mar 1.

Department of Pathology, Aviation General Hospital Beijing, China.

Aims: To demonstrate clinicopathologic features of Stewart-Treves syndrome (STS) including clinical manifestations, morphology, immunophenotype (especially c-MYC amplification), differential diagnosis, pathogenesis, treatment and prognosis.

Methods And Results: 17 cases of STS were retrospectively archived, involving 6 cases of postmastectomy, 3 cases of postoperative cervical cancer and 8 cases of chronic lymphatic obstruction without history of malignancy. Seven of 9 cancer patients had undergone radiotherapy. Read More

View Article and Full-Text PDF

Primary and secondary breast angiosarcoma: single center report and a meta-analysis.

Breast Cancer Res Treat 2019 Dec 14;178(3):523-533. Epub 2019 Sep 14.

Department of Medical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14203, USA.

Background: Primary and secondary breast angiosarcoma is a rare and aggressive malignancy with limited published literature. Optimal management is mostly based on expert opinion. Our study aims to describe a single institution experience with breast angiosarcoma and evaluate other publications on this topic to further clarify prognostic outcomes and treatment modalities in this disease. Read More

View Article and Full-Text PDF
December 2019

A case of Stewart-Treves Syndrome of the lower limbs: The usefulness of dermoscopy.

Int Wound J 2019 Oct 12;16(5):1237-1238. Epub 2019 Aug 12.

Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.

View Article and Full-Text PDF
October 2019

Secondary angiosarcoma: A fatal complication of chronic lymphedema.

J Surg Oncol 2020 Jan 24;121(1):85-90. Epub 2019 Jun 24.

Department of Tumor Orthopedics and Sarcoma Surgery, University Hospital Essen, University Essen-Duisburg, Germany.

Secondary Angiosarcoma (Stewart-Treves Syndrome) is a rare malignant cutaneous lesion, which arises in chronic lymphedema of the extremity, often observed after breast cancer treatment. We reviewed the history and the oncological outcome of two patients with this disease. Multimodal therapy including hyperthermic isolated limb perfusion with TNF-alpha and Melphalan, combined with radical resection of the affected skin and subcutaneous tissue including the fascia, with large safety margins may probably lead to better survival. Read More

View Article and Full-Text PDF
January 2020

Guillain-Barré syndrome in a cancer patient treated with bevacizumab.

Int Cancer Conf J 2018 Jul 2;7(3):87-92. Epub 2018 May 2.

Department of Clinical Oncology , Akita, Japan.

We describe a case of Guillain-Barré syndrome (GBS) in a patient treated with bevacizumab. Our case is a 60-year-old woman with Stewart-Treves syndrome (STS), and angiosarcoma of her left forearm, with onset 12 years after diagnosis with stage IIIA left breast cancer. She suffered from repeated distal metastases including skin, bone, and liver metastases. Read More

View Article and Full-Text PDF

Unsuspected Stewart-Treves syndrome clinically mimicked by apparent bullous erysipelas and a systematic review of dermatological presentations of the classical Stewart-Treves syndrome.

Cancer Rep (Hoboken) 2019 04 25;2(2):e1143. Epub 2018 Oct 25.

Departamento de Patologia, Hospital de Câncer de Barretos, Barretos, SP, Brazil.

Background: Stewart Treves-Syndrome (STS) was first characterized as angiosarcoma in the homolateral limb of a patient with breast cancer and lymphedema. Now, other conditions represent STS. It's a rare condition. Read More

View Article and Full-Text PDF

Secondary breast angiosarcoma: A multicentre retrospective survey by the national Italian association of Breast Surgeons (ANISC).

Breast 2019 Jun 7;45:56-60. Epub 2019 Mar 7.

IEO, Milano, Italy.

Background: Breast angiosarcoma is a malignant mesenchymal neoplasm, which accounts for approximately 2% of all soft tissue sarcomas. Secondary breast angiosarcoma (SBA) may be related to chronic lymphedema after a mastectomy with lymph node dissection (Stewart Treves syndrome) and previous radiotherapy for complications from breast radiation treatment. It is a very rare condition; therefore, diagnosis and management are still a challenge. Read More

View Article and Full-Text PDF

Prevention of tumor progression in Stewart-Treves syndrome with a low dose of pazopanib.

J Dermatol 2019 07 25;46(7):e263-e265. Epub 2019 Feb 25.

Department of Dermatology and Plastic Surgery, Akita University Graduate School of Medicine, Akita, Japan.

View Article and Full-Text PDF

Cutaneous angiosarcoma of the lower leg.

Cutis 2018 Oct;102(4):E8-E11

Wright State University Boonshoft School of Medicine, Dayton, and Jobst Vascular Institute/ProMedica Health System Toledo Hospital, Ohio, USA.

Angiosarcoma is a vascular malignancy that can affect various anatomic sites. Although rare, cutaneous angiosarcoma is the most common clinical manifestation, accounting for approximately 50% to 60% of cases. Cutaneous angiosarcoma typically is known to occur in 3 settings: (1) idiopathic, (2) following radiation treatment, and (3) in the setting of chronic lymphedema following mastectomy (known as Stewart-Treves syndrome). Read More

View Article and Full-Text PDF
October 2018

Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review.

SAGE Open Med Case Rep 2018 30;6:2050313X18796343. Epub 2018 Oct 30.

Division of Dermatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Chronic lymphedema is rarely complicated by an angiosarcoma. Angiosarcoma superimposed on chronic lymphedema (Stewart-Treves syndrome) is usually seen post breast cancer surgery accompanied by lymph node resection of the axilla. This is a case report of a 59-year-old male patient with elephantiasis that developed an angiosarcoma of the lower leg. Read More

View Article and Full-Text PDF
October 2018

A Series of Patients with Kaposi Sarcoma (Mediterranean/Classical Type): Case Presentations and Short Update on Pathogenesis and Treatment.

Open Access Maced J Med Sci 2018 Sep 20;6(9):1688-1693. Epub 2018 Sep 20.

Medical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, General Skobelev Nr 79, Sofia, Bulgaria.

Background: Kaposi's sarcoma was first described in 1872 by Moritz Kaposi. To date, it is considered a malignant disease is originating from the endothelial cells of the lymphatic vessels believed to be infected with HHV-8. The current classification defines four major epidemiological forms of Kaposi's sarcoma: classical, endemic, AIDS-associated, and iatrogenic. Read More

View Article and Full-Text PDF
September 2018

Cutaneous Angiosarcoma Postmastectomy (Stewart-Treves Syndrome).

J Belg Soc Radiol 2018 Oct 1;102(1):60. Epub 2018 Oct 1.

AZ Delta Roeselare, BE.

View Article and Full-Text PDF
October 2018