269 results match your criteria Steatocystoma Multiplex


Coexistence of Hidradenitis Suppurativa and Steatocystoma Multiplex; Is It a New Variant of Hidradenitis Suppurativa?

J Cutan Med Surg 2021 Apr 28:12034754211010145. Epub 2021 Apr 28.

12366 Department of Dermatology, Mayo Clinic, Rochester, MN, USA.

Hidradenitis suppurativa and steatocystoma multiplex may coexist in the same patient. The overlap of these 2 conditions could be suggestive of an unrecognized defect in follicular proliferation mutual in the pathogenesis of both conditions. Here we present 5 patients with both hidradenitis suppurativa and steatocystoma multiplex. Read More

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Familial neurofibromatosis type 1 has diverse manifestations in skin and is associated with steatocystoma multiplex.

Clin Exp Dermatol 2021 Apr 19. Epub 2021 Apr 19.

Department of Dermatology, the First Affiliated Hospital, Anhui Medical University, Institute of Dermatology, Anhui Medical University, Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, Hefei, China.

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An updated review of the sebaceous gland and its role in health and diseases Part 2: Pathophysiological clinical disorders of sebaceous glands.

Dermatol Ther 2021 Mar 19;34(2):e14862. Epub 2021 Feb 19.

Veterans Affairs Hospital and SUNY Downstate Dermatology Service, Brooklyn, New York, USA.

Sebaceous glands are sebum-secreting components of pilosebaceous units. In the second of this two-part series, we review the pathologies in which sebaceous glands are primarily and secondarily implicated. They are primarily involved in steatocystoma simplex and multiplex, sebaceous gland hyperplasia, sebaceoma, sebaceous adenoma, sebaceous carcinoma, nevus sebaceus, and folliculosebaceous cystic hamartoma. Read More

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Imaging features of steatocystoma multiplex- back to basics.

Breast J 2021 Apr 1;27(4):389-390. Epub 2021 Feb 1.

Consultant Breast Radiologist, Mount Elizabeth Novena Hospital, Singapore.

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An updated review of the sebaceous gland and its role in health and diseases Part 1: Embryology, evolution, structure, and function of sebaceous glands.

Dermatol Ther 2021 Jan 1;34(1):e14695. Epub 2021 Jan 1.

Veterans Affairs Hospital and SUNY Downstate Dermatology Service, Brooklyn, New York, USA.

Sebaceous glands are sebum-secreting components of pilosebaceous units. The embryological development of the sebaceous gland follows that of the hair follicle and epidermal tissue, beginning between weeks 13 and 16 of fetal development. New sebaceous glands do not normally develop following birth, but their size increases with age. Read More

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January 2021

A Case of Steatocystoma Multiplex in a Psoriatic Patient during Treatment with Anti-IL-12/23.

Skin Appendage Disord 2020 Sep 14;6(5):309-311. Epub 2020 Jul 14.

Department of Dermatology, University of Naples Federico II, Naples, Italy.

Steatocystoma multiplex (SM) is an autosomal dominant disorder developing in adolescence or early adult age. The occurrence of multiple asymptomatic cutaneous cysts on the axillae, groin, trunk, and limbs characterizes the disease. SM is associated with a missense mutation in the keratin 17 gene (KRT17), a gene encoding for a type I intermediate filament (keratin 17 [K17]), mainly expressed in the epithelial appendages (hair follicles and sebaceous glands). Read More

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September 2020

Palatal steatocystoma simplex-a rare oral finding at an even rarer location.

J Surg Case Rep 2020 Oct 9;2020(10):rjaa347. Epub 2020 Oct 9.

Department of Oral, Maxillofacial and Plastic Surgery, University Medical Center Mainz, Mainz, Germany.

Steatocystoma is a rare, benign cyst that mostly originates from a dermal sebaceous gland. It can be divided into steatocystoma multiplex-with multiple locations-and steatocystoma simplex occurring at a single site. The lesion is mostly located on the skin but can be found on other locations as well. Read More

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October 2020

Ultrasound-Guided Intralesional Cryotherapy for Treatment of Steatocystoma Multiplex.

Authors:
Chun-Yu Cheng

Dermatol Surg 2020 Sep 8. Epub 2020 Sep 8.

Department of Dermatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.

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September 2020

Parameatal Median Raphe Cyst: A Case Report of a Midline Developmental Defect of True Urogenital Origin.

Indian Dermatol Online J 2020 Mar-Apr;11(2):216-218. Epub 2020 Mar 9.

Department of Dermatology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India.

Median raphe cyst (MRC) is an uncommon, asymptomatic benign lesion, that may present anywhere on the midline ridge between the external urethral meatus and the anus. Although they are developmental in origin, they often present in the postpubertal age, aggravated by trauma, and are frequently infected secondarily. MRCs are often misdiagnosed as epidermal cysts, steatocystoma multiplex, and eccrine cystadenomas. Read More

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A case of late onset steatocystoma multiplex.

Postepy Dermatol Alergol 2020 Feb 9;37(1):117-118. Epub 2020 Mar 9.

Institute of Dermatology, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Chinese Academy of Medical Science and Peking Union Medical College, Nanjing, China.

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February 2020

A simple modified surgical technique combined with tissue adhesive for steatocystoma multiplex.

J Cosmet Dermatol 2021 Jan 10;20(1):218-221. Epub 2020 May 10.

Department of Dermatologic Surgery, Shanghai Skin Diseases Hospital, Shanghai, China.

Background: Steatocystoma multiplex (SM) is a disorder of the pilosebaceous unit characterized by multiple sebum-containing dermal cysts. Psychological distress of patients is always derived from these undesirable lesions. Although various treatments have been attempted to improve cosmetic outcomes, no optimal treatment strategy has been established to date. Read More

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January 2021

Ultrasound Morphologic Features of Steatocystoma Multiplex With Clinical Correlation.

J Ultrasound Med 2020 Nov 1;39(11):2255-2260. Epub 2020 May 1.

Department of Dermatology, Universidad de Chile, Santiago, Chile.

The ultrasound features of 87 steatocytoma multiplex (SCM) lesions detected in 9 patients are reported. Steatocytoma multiplex is a hamartomatous condition derived from the pilosebaceous duct junction that generates multiple cutaneous cystic lesions. It appeared as clusters of well-defined hypoechoic nodules with mild posterior enhancement in 100% of cases, with both dermal and subcutaneous locations in 67%. Read More

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November 2020

Numerous flesh-colored nodules on the trunk.

Cutis 2019 Dec;104(6):E22-E24

Division of Dermatology, University of Kansas, Kansas City, USA.

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December 2019

Steatocystoma multiplex: A case report of a rare entity.

Imaging Sci Dent 2019 Dec 24;49(4):317-321. Epub 2019 Dec 24.

Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.

Steatocystoma multiplex is an uncommon benign skin disease, which typically manifests as numerous intradermal cysts that can be scattered anywhere on the body. Although usually asymptomatic, it can be significantly disfiguring. One type of steatocystoma multiplex is known to be associated with the autosomal dominant inheritance of a mutation in the gene coding for keratin 17 (). Read More

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December 2019

Dermpath & Clinic: Multiple nodules in the axillae: is it that old chestnut Hidradenitis suppurativa again?

Eur J Dermatol 2019 Oct;29(5):569-570

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Josef-Schneider-Str 2, 97080 Würzburg, Germany.

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October 2019

Steatocystoma multiplex suppurativa associated with hidradenitis suppurativa successfully treated with adalimumab.

J Eur Acad Dermatol Venereol 2019 Oct;33 Suppl 6:42-44

Section of Dermatology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

Steatocystoma multiplex (SM) is a rare autosomal dominant disease characterized by multiple asymptomatic intradermal true sebaceous cysts of variable size. These lesions may occasionally rupture, become inflamed, painful and heal with scarring [SM suppurativa (SMS)], thus sharing overlapping features with hidradenitis suppurativa (HS). The question of whether SMS simply mimics HS or if the two diseases may be associated remains open. Read More

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October 2019

Dermatoscopy for the rapid diagnosis of Talaromyces marneffei infection: a case report.

BMC Infect Dis 2019 Aug 9;19(1):707. Epub 2019 Aug 9.

Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.

Background: Talaromyces marneffei is a thermally dimorphic fungus endemic in south-east Asia. It predominantly occurs in both immunocompromised and immunosuppressed patients and can be fatal if diagnosis and treatment are delayed. The clinical manifestations of T. Read More

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Coexistence of steatocystoma multiplex and hidradenitis suppurativa: Assessment of this unique association by means of ultrasonography and Color Doppler.

Skin Res Technol 2019 Nov 28;25(6):877-880. Epub 2019 Jul 28.

UOC Dermatologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Background: Steatocystoma multiplex (SM) is an uncommon skin disease manifesting as multiple sebum-containing cysts arising in pilosebaceous unit-rich body areas. Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory disease affecting the apocrine gland-bearing skin and presenting with both pseudocystic and inflammatory nodules, abscesses and fistulas. Considering that genetics has been reported to play a role in both entities, the albeit rare association between them suggests a shared genetic background. Read More

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November 2019

Mutation analysis of the KRT17 gene in steatocystoma multiplex and a brief literature review.

Clin Exp Dermatol 2020 Jan 17;45(1):132-134. Epub 2019 Sep 17.

Shandong Provincial Hospital for Skin Diseases, Shandong University, 27397 Jingshi Road, Jinan, Shandong, 250022, China.

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January 2020

Steatocystoma Multiplex Suppurativa: A Case with Unusual Giant Cysts over the Scalp and Neck.

Case Rep Dermatol 2019 Jan-Apr;11(1):71-76. Epub 2019 Mar 19.

Department of Dermatology, King Saud University Medical City, Riyadh, Saudi Arabia.

Steatocystoma multiplex (SM) is a rare hamartomatous malformation of the pilosebaceous duct junction. Most cases of SM are sporadic, although less common autosomal dominant inherited forms have been reported. Steatocystoma multiplex suppurativa (SMS) is a much rarer inflammatory variant of SM, associated with severe inflammatory lesions resembling those of hidradenitis suppurativa. Read More

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1927-nm fiber-optic diode laser: A novel therapeutic option for facial steatocystoma multiplex.

J Cosmet Dermatol 2018 Dec 30. Epub 2018 Dec 30.

Department of Dermatology, College of Medicine, University of Hanyang, Seoul, Korea.

Steatocystoma multiplex (SM) is a cutaneous disorder that presents with multiple yellowish intradermal cysts originating from the pilosebaceous ducts. Although various treatments have been attempted to improve cosmetic outcomes, no optimal treatment strategy has been established to date. A 41-year-old man presented with a 10-year history of multiple skin-colored papulonodules over his entire body. Read More

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December 2018

Numerous asymptomatic dermal cysts: Diagnosis and treatment of steatocystoma multiplex.

Can Fam Physician 2018 12;64(12):892-899

Lecturer and staff dermatologist in the Division of Dermatology at the University of Toronto.

Objective: To provide family physicians with the information needed to recognize, diagnose, and discuss available treatment options for steatocystoma multiplex (SM).

Sources Of Information: A comprehensive PubMed search using as either a text word or a MeSH term was conducted, and articles reporting on treatment outcomes were included.

Main Message: Steatocystoma multiplex is a benign disorder often characterized by numerous asymptomatic dermal cysts on the trunk, arms, axillae, face, thighs, and scalp. Read More

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December 2018

Treatment of steatocystoma multiplex on axillae using keyhole approach technique.

J Cosmet Laser Ther 2019 16;21(4). Epub 2018 Oct 16.

Department of Dermatology, Ho Wen Tsao Skin Clinic , New Taipei City , Taiwan, ROC.

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Keratin 17 in disease pathogenesis: from cancer to dermatoses.

J Pathol 2019 02 7;247(2):158-165. Epub 2018 Dec 7.

Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, PR, China.

Keratin 17 (K17) is a type I intermediate filament mainly expressed in the basal cells of epithelia. As a multifaceted cytoskeletal protein, K17 regulates a myriad of biological processes, including cell proliferation and growth, skin inflammation and hair follicle cycling. Aberrant overexpression of K17 is found in various diseases ranging from psoriasis to malignancies such as breast, cervical, oral squamous and gastric carcinomas. Read More

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February 2019

Huge Steatocystoma Multiplex with New Point Mutation in the Exon 1 of KRT 17 Gene.

Ann Dermatol 2018 Oct 28;30(5):633-635. Epub 2018 Aug 28.

Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.

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October 2018

Steatocystoma Simplex on the Scalp: A Case Report.

Mymensingh Med J 2018 Jul;27(3):669-671

Dr Fahmida Akter Rima, Lecturer, Department of Pathology, Dhaka Medical College, Dhaka, Bangladesh.

Steatocystoma is a benign adnexal tumor arising from the pilosebaceous duct junction. It can be classified into two groups (steatocystoma simplex and steatocystoma multiplex). Steatocystoma simplex, which presents as a solitary, non-herited very rare lesion in adult. Read More

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An Unusual Case of Facial Steatocystoma Multiplex: A Clinicopathologic and Dermoscopic Report.

Dermatopathology (Basel) 2018 Apr-Jun;5(2):58-63. Epub 2018 May 22.

Department of Dermatology, Lokmanya Tilak Municipal Medical College (LTMMC) and Sion General Hospital, Mumbai, India.

Background: Steatocystoma multiplex is a benign skin disorder originating from the sebaceous and nevoid ducts. Commonly classified under hamartomas, they are distributed over the trunk, neck, axillae, and groin.

Methods: A 28-year-old male patient complained of multiple, asymptomatic skin-colored nodules over the face of 10-year duration. Read More

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A novel APC mutation identified in a large Chinese family with familial adenomatous polyposis and a brief literature review.

Mol Med Rep 2018 Aug 5;18(2):1423-1432. Epub 2018 Jun 5.

Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, P.R. China.

Familial adenomatous polyposis (FAP), an autosomal dominant disease, is a colon cancer predisposition syndrome that manifests as a large number of adenomatous polyps. Mutations in the Adenomatous polyposis coli (APC) gene are responsible for the majority of cases of FAP. The purpose of the present study was to report the clinical features of a Chinese family with FAP and screen for novel mutations using the targeted next‑generation sequencing technology. Read More

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Eruptive Vellus Hair Cyst: An Uncommon and Underdiagnosed Entity.

Int J Trichology 2018 Jan-Feb;10(1):31-33

Department of Dermatology, Hindu Rao Hospital and NDMC Medical College, NewDelhi, India.

Eruptive vellus hair cyst (EVHC) is a rare follicular developmental abnormality of the vellus hair follicles. They are usually seen in children, adolescents, or young adults and manifest as reddish-brown smooth papules most commonly involving the chest, limbs, and abdomen. An 18-year-old male presented with asymptomatic papules on the trunk and flexor aspect of both forearms for the past 2 years. Read More

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February 2018