278 results match your criteria Steatocystoma Multiplex
J Cosmet Laser Ther 2018 Oct 16. Epub 2018 Oct 16.
b Department of Dermatology , Ho Wen Tsao Skin Clinic , New Taipei City , Taiwan, ROC.
J Pathol 2018 Oct 10. Epub 2018 Oct 10.
Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, PR, China.
Keratin 17 (K17) is a type I intermediate filament mainly expressed in the basal cells of epithelia. As a multifaceted cytoskeletal protein, K17 regulates a myriad of biological processes, including cell proliferation and growth, skin inflammation and hair follicle cycling. Aberrant overexpression of K17 is found in various diseases ranging from psoriasis to malignancies such as breast, cervical, oral squamous and gastric carcinomas. Read More
Mymensingh Med J 2018 Jul;27(3):669-671
Dr Fahmida Akter Rima, Lecturer, Department of Pathology, Dhaka Medical College, Dhaka, Bangladesh.
Steatocystoma is a benign adnexal tumor arising from the pilosebaceous duct junction. It can be classified into two groups (steatocystoma simplex and steatocystoma multiplex). Steatocystoma simplex, which presents as a solitary, non-herited very rare lesion in adult. Read More
Dermatopathology (Basel) 2018 Apr-Jun;5(2):79-85. Epub 2018 Jun 7.
Department of Pharmacology and Toxicology, University of Geneva, Geneva, Switzerland.
Cutaneous cysts have been classified by dermatopathologists in many different ways. Here, we propose a novel classification of cutaneous adnexal cysts according to their origin in the folliculosebaceous unit and the sweat glands. By examining the lining of the cystic structure, its origin can be easily identified. Read More
Dermatopathology (Basel) 2018 Apr-Jun;5(2):58-63. Epub 2018 May 22.
Department of Dermatology, Lokmanya Tilak Municipal Medical College (LTMMC) and Sion General Hospital, Mumbai, India.
Background: Steatocystoma multiplex is a benign skin disorder originating from the sebaceous and nevoid ducts. Commonly classified under hamartomas, they are distributed over the trunk, neck, axillae, and groin.
Methods: A 28-year-old male patient complained of multiple, asymptomatic skin-colored nodules over the face of 10-year duration. Read More
Mol Med Rep 2018 Aug 5;18(2):1423-1432. Epub 2018 Jun 5.
Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, P.R. China.
Familial adenomatous polyposis (FAP), an autosomal dominant disease, is a colon cancer predisposition syndrome that manifests as a large number of adenomatous polyps. Mutations in the Adenomatous polyposis coli (APC) gene are responsible for the majority of cases of FAP. The purpose of the present study was to report the clinical features of a Chinese family with FAP and screen for novel mutations using the targeted next‑generation sequencing technology. Read More
Int J Trichology 2018 Jan-Feb;10(1):31-33
Department of Dermatology, Hindu Rao Hospital and NDMC Medical College, NewDelhi, India.
Eruptive vellus hair cyst (EVHC) is a rare follicular developmental abnormality of the vellus hair follicles. They are usually seen in children, adolescents, or young adults and manifest as reddish-brown smooth papules most commonly involving the chest, limbs, and abdomen. An 18-year-old male presented with asymptomatic papules on the trunk and flexor aspect of both forearms for the past 2 years. Read More
Indian J Dermatol 2017 Nov-Dec;62(6):661-664
Department of Dermatology, Venereology and Leprosy, School of Tropical Medicine, Kolkata, West Bengal, India.
Pachyonychia Congenita (PC) refers to a group of autosomal dominant disorders with variable clinical presentations. While nail dystrophy and plantar keratoderma are the most consistent features in all the variants, a myriad of other manifestations has been observed. This report highlights a case of young female presenting with multiple asymptomatic cutaneous cysts associated with plantar kearatoderma and nail dystrophy. Read More
Clin Exp Dermatol 2018 Mar 8;43(2):205-208. Epub 2017 Dec 8.
Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.
Am J Dermatopathol 2018 Jun;40(6):401-408
Department of Pathology, Montefiore Medical Center, Bronx, NY.
There are 36 cases of complex poroid tumors with folliculosebaceous and apocrine differentiation reported in the literature. The authors evaluated 111 poroid tumors including 63 typical eccrine poromas and 48 poroid tumors with folliculosebaceous elements. Folliculosebaceous poroid tumors (FSPT) had basaloid and squamous cells (100%), ducts with steatocystoma-like cuticles and holocrine secretions (89. Read More
Int J Trichology 2017 Jul-Sep;9(3):119-121
Department of Pathology, Sonoscan Healthcare, Malda, West Bengal, India.
Any cutaneous cyst differentiating toward two or more pilosebaceous components is known as follicular hybrid cyst (FHC). A combination of epidermal and trichilemmal cyst is its most frequent example. Other combinations of pilosebaceous derivatives occur uncommonly as well. Read More
Cutis 2017 Jul;100(1):E23-E26
Department of Dermatology and the Department of Laboratory Medicine, Mayo Clinic, Rochester, Minnesota, USA.
An association between steatocystoma multiplex (SCM) and eruptive vellus hair cysts (EVHCs) has been recognized. Steatocystoma multiplex and EVHC have similar clinical features but distinctive histologic features. Rare cases of co-occurrence of these conditions have been known to occur on the trunk and the forehead. Read More
J Cutan Med Surg 2017 Nov/Dec;21(6):564-567. Epub 2017 Jun 28.
1 Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
Eruptive vellus hair cysts (EVHCs) often occur on the trunk and limbs. Facial involvement is uncommon. Autosomal dominant inheritance has been described, but associated extracutaneous anomalies have not. Read More
Case Rep Dermatol Med 2017 5;2017:3861972. Epub 2017 Apr 5.
College of Medicine, University of Illinois-Chicago, Urbana Campus, 506 South Mathews Ave., 190 Medical Sciences Building, MC-714, Urbana, IL 61801, USA.
. Steatocystoma multiplex (SM) and eruptive vellus hair cysts (EVHC) are uncommon benign tumors of the pilosebaceous unit. Both SM and EVHC are characterized by smooth, asymptomatic papules or nodules, most commonly presenting on the chest, limbs, and abdomen. Read More
An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):51-53
Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil.
Steatocystoma multiplex is a rare genetic disorder characterized by the presence of hamartomatous malformations at the junction of the pilosebaceous duct. It consists of encapsulated cystic lesions in the dermis, with adjacent sebaceous gland. When associated with inflammation, resembling hidradenitis, it is called steatocystoma multiplex suppurativa, a condition rarely reported. Read More
Lepr Rev 2016 Dec;87(4):543-7
Histoid leprosy is an unusual variant of lepromatous leprosy posing difficulties for diagnosis as well as treatment even to the experts. We report a case of a 73 year old male from the hilly region of Nepal, who presented with multiple asymptomatic scrotal nodules for 3 months. Though clinical diagnoses were pilomatricoma and steatocystoma multiplex; histopathological examination was consistent with that of histoid leprosy. Read More
BMC Ophthalmol 2016 Oct 19;16(1):183. Epub 2016 Oct 19.
Department of Oculoplastic, Orbital & Lacrimal Surgery, Orbital & Lacrimal Surgery, Aichi Medical University Hospital, 1-1 Yazako-Karimata, Nagakute, Aichi, 480-1195, Japan.
Background: This is the third reported case of a steatocystoma simplex in the lacrimal caruncle.
Case Presentation: A 60-year-old male presented with a history of a slowly progressing mass in the right lacrimal caruncle since several years before his initial visit. At the first examination, a yellowish, relatively smooth surface mass was observed in the right lacrimal caruncle. Read More
Indian J Surg 2016 Aug 19;78(4):329-30. Epub 2016 Mar 19.
Bharati Vidyapeeth Deemed University Medical College and Hospital, Sangli, India.
Idiopathic scrotal calcinosis (ISC) is a rare benign condition which presents with multiple, asymptomatic, and painless nodules on the scrotal skin wall. The lesions have been attributed as sebaceous cysts, calcified steatocystoma, fibroma, atheroma, and xanthoma. Shapiro et al. Read More
Indian Dermatol Online J 2016 Jul-Aug;7(4):278-80
Department of Dermatology, Maharajah's Institute of Medical Sciences, Nellimarla, Andhra Pradesh, India.
Pachyonychia congenita is a rare type of ectodermal dysplasia further classified into 4 types. Cutaneous manifestations seen in most of the cases of Pachyonychia congenita include palmoplantar keratoderma, follicular hyperkeratosis, wedge shaped nails, oral leukokeratosis and woolly hair. A 25-year-old male presented to us with thickened nails and scanty scalp hair. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2016 Mar;30(5):409-10
Epidermnoid cysts are henign, cutaneous cysts which commonly occur on face, neck and trunk. Retroauricular epidermoid cyst is rare reported which should be differentiated from auricle pseudocyst, lipoma, steatocystoma and fibroma. The hitopathological examination is a gold standard of diagnosis. Read More
J Cosmet Laser Ther 2016 Nov 19;18(7):364-366. Epub 2016 Jul 19.
b Department of Dermatology , University of California Irvine , Irvine , CA , USA.
Steatocystoma multiplex is a well-recognized condition in which subjects develop dermal cysts generally inherited in an autosomal dominant fashion, though these can occur sporadically. This case report describes the successful treatment of a 51-year-old woman with steatocystomata limited to the face, who after two treatments with a fractionated ablative carbon dioxide laser remained free of cysts for three years. We conclude that this treatment should be considered as an efficient and effective treatment option for patients with steatocystoma multiplex. Read More
Ann Plast Surg 2017 Feb;78(2):e1-e3
From the Divisions of *General Surgery, and †Plastic and Reconstructive Surgery, Mayo Clinic Hospital, Phoenix; and ‡Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ.
A question arose in our practice of whether all cysts considered sebaceous should be sent for pathologic evaluation. To address this controversial topic, we performed a retrospective study of our single institution's histopathology database. A natural language search of the CoPath database across the institution was undertaken using the diagnosis of sebaceous cyst, epidermal cyst, epidermoid cyst, epithelial cyst, infundibular cyst, pilar cyst, trichilemmal cyst, and steatocystoma. Read More
J Dermatol 2016 Sep 11;43(9):1111-2. Epub 2016 Mar 11.
Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.
J Med Case Rep 2016 Mar 8;10:49. Epub 2016 Mar 8.
Biodiversity Research Center, Federal University of Roraima (CBio/UFRR), Boa Vista - RR, Brazil.
Background: Steatocystoma simplex is an uncommon skin lesion with a histological pattern that is identical to that of steatocystoma multiplex. We are reporting this case of steatocystoma simplex for its uncommon location in the penile foreskin, and its occurrence in a Wapishana man.
Case Presentation: A 56-year-old man of Wapishana ethnicity presented with complaints of referred penile discomfort and pain during sexual intercourse for 5 years. Read More
Chin Med J (Engl) 2016 Feb;129(3):377-8
Institute of Plastic and Craniofacial Surgery, SOBRAPAR Hospital, Campinas, São Paulo, Brazil.
Mol Med Rep 2015 Oct 8;12(4):5072-6. Epub 2015 Jul 8.
Department of Dermatology, Hainan Provincial Hospital of Skin Disease, Haikou, Hainan 570206, P.R. China.
Steatocystoma multiplex (SM) is an uncommon disorder, characterized by numerous skin‑colored subcutaneous cysts. A number of SM pedigrees have been identified with mutations in the keratin 17 (KRT17) gene. The present study examined a four‑generation Chinese pedigree with an autosomal dominant mode of inheritance and examined its genetic basis. Read More
Eur J Dermatol 2015 Jul-Aug;25(4):358-9
Netherlands Institute for Pigment Disorders (SNIP),, Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands.
J Neuroimmunol 2015 May 11;282:21-4. Epub 2015 Mar 11.
Department of Neuroendocrinology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland. Electronic address:
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. Obesity may increase the risk of developing MS. The aim of this study was to evaluate copeptin and cortisol plasma levels in newly diagnosed untreated MS patients and to determine whether copeptin and cortisol are related to the patients' clinical statuses. Read More
J Dermatol 2015 May 21;42(5):521-3. Epub 2015 Mar 21.
Department of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.
Steatocystoma multiplex (SM) is an unusual benign disorder of the pilosebaceous duct characterized by multiple cysts with little or no nail and hair involvement. We report a 30-year-old woman with multiple cystic nodules located on the neck, axillae and forearms as well as patchy scalp alopecia. Histopathological examination of the lesions was diagnostic of SM. Read More
Skinmed 2014 Sep-Oct;12(5):267-9
J Dermatol 2015 Mar 13;42(3):305-10. Epub 2015 Jan 13.
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
We herein report two cases of cystic trichoblastoma with an immunohistochemical study. The histopathological findings in these cases included new information, namely, their being composed of two and three cysts, the cystic components had features of a steatocystoma and a hybrid cyst in one case, and there were projections of an aggregation of trichoblastoma, as well as papillary projections of follicular germinative cells, from the cyst walls. The follicular germinative cells observed in the papillary projections and in the aggregations of trichoblastoma expressed cytokeratin-15 (clone C8/144B) and PHLDA1, markers of follicular stem cells. Read More
Clin Exp Ophthalmol 2015 May-Jun;43(4):385-7. Epub 2014 Oct 22.
Division of Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
Acta Derm Venereol 2015 Mar;95(3):353-4
Department of Dermatology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Kita-gun Miki-cho, 761-0793 Kagawa, Japan.
J Eur Acad Dermatol Venereol 2015 Oct 30;29(10):2051-3. Epub 2014 Jul 30.
Department of Dermatology und Venereology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Am J Dermatopathol 2015 Sep;37(9):733-4
Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.
Am J Dermatopathol 2015 Nov;37(11):871-3
Department of Histopathology, National Reference Laboratory, Dr Lal Pathlabs, Delhi, India.
Dermatol Surg 2014 Jun;40(6):658-62
*Both the authors are affiliated with the Manchester Laser Unit, Dermatology Centre, Salford Royal NHS Foundation Trust, Manchester, United Kingdom.
Background: Steatocystoma multiplex (SM) is a rare condition that presents as multiple dermal cysts, the appearance of which can have a significant impact on the patients' quality of life. Treatment options for SM are limited to surgical excision.
Objective: To present our experience of treating 8 SM cases using a novel approach that uses the carbon dioxide (CO2) laser and to explore patients' views about the treatment. Read More
Br J Dermatol 2014 Dec 2;171(6):1565-7. Epub 2014 Nov 2.
Department of Dermatology, Montauban Hospital, Montauban, France.
Acta Derm Venereol 2015 Jan;95(1):121-3
Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Køgevej 7-13, DK-4000 Roskilde, Denmark.
Am J Dermatopathol 2014 Nov;36(11):892-8
Department of Dermatology, University of Münster, Münster, Germany.
Goltz-Gorlin syndrome presents with multiple basal cell carcinomas, odontogenic keratocysts, and cutaneous cysts, among other manifestations. The cutaneous cysts have been described as both epidermoid cysts and keratocysts but were not further characterized. Light microscopic examinations were made on 23 cutaneous cysts in 4 patients associated with Goltz-Gorlin syndrome located on extremities, face, trunk, palms, and soles and compared with nonsyndromic vellus hair cysts, steatocystomas, and hybrid cysts. Read More
J Cutan Pathol 2014 Aug 19;41(8):677-9. Epub 2014 Mar 19.
Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.
Steatocystoma multiplex is characterized by the development of numerous steatocystomas. The condition has occasionally been related to congenital bilateral preauricular sinuses. Herein, we present the third case of such an association, a 34-year-old male who was born with bilateral preauricular sinuses that were surgically repaired. Read More
Chin J Cancer Res 2014 Feb;26(1):E5-9
1 Department of Internal Medicine, 2 Department of Dermatology, 3 Department of Pathology, Chung Shan Medical University Hospital and School of Medicine, Chung Shan Medical University, Taichung 402, Taiwan, China.
Cutaneous metastases are rare and seldom present at the time of first diagnosis of cancer. Data from various studies show that 1-12% of lung cancer patients experience tumor spread to the skin. The scalp, chest, and abdomen are favored sites of skin metastases from lung cancers, but metastases to multiple skin sites in a single patient are rarely reported. Read More
Indian J Dermatol Venereol Leprol 2014 Jan-Feb;80(1):89-90
Department of Dermatology, Chonbuk National University Medical School; Research Institute of Clinical Medicine of Chonbuk National University Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, South Korea.
Ann Dermatol 2013 Nov 30;25(4):508-10. Epub 2013 Nov 30.
Institute of Dermatology, Anhui Medical University, Hefei, Anhui, China. ; The MOE Key Laboratory of Dermatology, Hefei, Anhui, China. ; Department of Dermatology and Venereology, the First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China.
Dermatol Online J 2013 Dec 16;19(12):20721. Epub 2013 Dec 16.
New York University School of Medicine.
Steatocystoma multiplex is a rare condition that is characterized by cutaneous cysts and may be inherited in an autosomal dominant manner or may occur sporadically. The pathogenesis is hypothesized to involve mutations in the keratin 17 gene. There are no internal manifestations. Read More
Skinmed 2013 Sep-Oct;11(5):301-3
Dermatology Department, Hospital Nacional Profesor Alejandro Posadas, Buenos Aires, Argentina.
Our patient is a 29-year-old woman without any previous disease who presented with different kinds of lesions on her face, neck, and chest. She first noticed the lesions 10 years ago and, since that time, they have become more numerous. She has no affected relatives. Read More
Clin Nucl Med 2014 Sep;39(9):822-4
From the Departments of *Nuclear Medicine, †Pathology, and ‡Respiratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.
Steatocystoma multiplex is a rare, benign, sporadic or familial disorder. Steatocystoma multiplex with extensive calcification is extremely rare. A 57-year-old man presented fever and cough with expectoration for 3 weeks. Read More
Acta Dermatovenerol Croat 2013 ;21(3):205-6
Derya Uçmak, MD, Department of Dermatology, Dicle University Faculty of Medicine, Diyarbakir, Turkey;
Actas Dermosifiliogr 2014 Jan-Feb;105(1):85-6. Epub 2013 Oct 16.
Servicio de Dermatología, Hospital Gregorio Marañón, Madrid, España.