1,219 results match your criteria Squamous Cell Carcinoma Eyelid


Massive Orbital Myiasis Caused by Complicating Eyelid Malignancy.

Case Rep Ophthalmol Med 2020 30;2020:5618924. Epub 2020 Apr 30.

Department of Ophthalmology, Meir Medical Center, Kfar Saba, Israel.

. To report a case of massive orbital myiasis caused by the larvae of , complicating eyelid malignancy. . Read More

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http://dx.doi.org/10.1155/2020/5618924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210513PMC

Expression levels of angiogenic growth factors in feline squamous cell carcinoma.

Acta Vet Hung 2020 May 1. Epub 2020 May 1.

1Department of Pathology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Kurupelit, 55200 Atakum, Samsun, Turkey.

Squamous cell carcinoma (SCC) is the most common malignant neoplasm of the skin in cats. Tumour angiogenesis is the pivotal event for tumour progression and metastasis. We assessed protein and gene expression of angiogenic growth factors including bFGF, VEGF-C, TGF-β, PDGF-A, PDGF-C and PDGFR-α that possibly contribute to the angiogenic phenotype of feline SCC (FSCC) and could, therefore, be a good target in the treatment of SCC. Read More

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http://dx.doi.org/10.1556/004.2020.00005DOI Listing

Rapid Rehabilitation With Skin-Muscle Sparing Orbital Exenteration: A Single-Center Series.

Ophthalmic Plast Reconstr Surg 2020 May 4. Epub 2020 May 4.

Adnexal Service, Moorfields Eye Hospital, London, United Kingdom.

Aims: To examine the features and clinical management of patients who underwent skin-muscle sparing orbital exenteration in a tertiary referral center.

Patients And Method: Retrospective case-note review for patients undergoing skin-muscle sparing orbital exenteration at Moorfields Eye Hospital between 1997 and 2012. Patient demographics, clinical features, histopathology, clearance, surgery, adjuvant therapy, and outcomes were analyzed. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001677DOI Listing

Screening and Intervention for Skin Cancer in the Galapagos.

Ann Plast Surg 2020 Apr 28. Epub 2020 Apr 28.

Division of Plastic and Reconstructive Surgery at Stony Brook University Hospital.

Objective: This study aimed to assess the general dermatological needs and correlation of tentative skin cancer screening diagnoses with histopathological confirmation in the highly sun-exposed locals of the Galapagos Islands.

Methods: An institutional review board-approved prospective study was performed at Blanca's House, a nonprofit surgical volunteer organization, free clinics in the Galapagos. After consent, a 40-item modified SPOTme-inspired questionnaire was completed. Read More

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http://dx.doi.org/10.1097/SAP.0000000000002345DOI Listing

Subtotal Exenteration of the Orbit for Benign Orbital Disease.

J Craniofac Surg 2020 Mar 27. Epub 2020 Mar 27.

Department of Ophthalmology.

Purpose: Total exenteration of the orbit with removal of the eye globe and surrounding tissues is most frequently indicated for malignant tumors. The indications for exenteration of the orbit for benign orbital lesion are rare. Not adequately treated infection of the orbit by systemic antibiotics can lead to destructive changes of soft tissues in the region of the orbit and partial exenteration with eyelid sparing technique is necessary. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006357DOI Listing

Anatomic Features of Head and Neck Keratinocyte Cancer in Virginia.

Dermatol Surg 2020 Mar 18. Epub 2020 Mar 18.

Departments of Oculoplastic Surger, and.

Background: Keratinocyte cancer (KC) patients benefit from early diagnosis. We describe here the anatomy of head/neck KCs to help guide screening efforts.

Objective: To examine lesion frequency and anatomic distribution of head and neck KC. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002370DOI Listing

[Therapeutic alternatives to surgical treatment of malignant eyelid tumors and their precursors].

Ophthalmologe 2020 May;117(5):478-483

Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig AöR, Leipzig, Deutschland.

The treatment of choice for malignant eyelid tumors is surgical excision. If this is not feasible or undesirable, a number of alternative treatments are available. Possible systemic preparations are vismodegib and sonidegib for basal cell carcinoma as well as cetuximab and cemiplimab for squamous cell carcinoma. Read More

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http://dx.doi.org/10.1007/s00347-020-01072-yDOI Listing

Periorbital squamous cell carcinoma with simultaneous adenocarcinoma in the right orbit.

Int J Surg Case Rep 2020 6;67:187-190. Epub 2020 Feb 6.

Northwick Park Hospital London, HA1 3UJ, United Kingdom. Electronic address:

Introduction: Cutaneous squamous cell carcinoma (cSCC) is an invasive and malignant tumour that is common in the orbital region. However, adenocarcinoma of the lacrimal gland has an incidence of less than one case per million per year. We present a patient who experienced a cSCC and adenocarcinoma of the lacrimal gland, which is unusual for both these cancers to present in the same patient in such close proximity. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025094PMC
February 2020

Eyelid and Orbital Involvement in HIV Infection - An African Perspective.

Ocul Immunol Inflamm 2020 Feb 14:1-9. Epub 2020 Feb 14.

Division of Ophthalmology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Both infective and neoplastic eyelid and orbital conditions in human immunodeficiency virus (HIV) infected patients are often the result of opportunistic or co-infections (OI). In most cases, these clinical findings in younger patients alert the physician to suspected underlying HIV infection. When the eyelids and periorbital skin are primarily involved in OI with varicella-zoster virus it is called Herpes Zoster Ophthalmicus. Read More

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http://dx.doi.org/10.1080/09273948.2019.1705987DOI Listing
February 2020

[Interdisciplinary Management of Tumours of the Eyelid and Periorbital Region].

Klin Monbl Augenheilkd 2020 Jan 22;237(1):46-56. Epub 2020 Jan 22.

Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Universitätsklinikum Halle (Saale), Martin-Luther-Universität Halle-Wittenberg, Halle (Saale).

Introduction: Skin malignancies are typically localised in areas of the head that are exposed to the sun. Basal cell carcinomas (BCC) are the most frequent malignancies on the facial skin. Their incidence is raising - due to demographic changes. Read More

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http://dx.doi.org/10.1055/a-1082-1454DOI Listing
January 2020

Photodynamic therapy for squamous cell carcinoma of the index finger: A case report.

Authors:
Junhong Ma Xin Wang

Photodiagnosis Photodyn Ther 2020 Mar 13;29:101661. Epub 2020 Jan 13.

Department of Dermatology, The First Affiliated Hospital of Tsinghua University, Beijing, China.

Skin squamous cell carcinoma (SCC) is the second most common skin cancer, and surgical resection is the first choice of treatment. However, some special sites such as lips, eyelids, distal fingers and genital areas are not suitable for operation. We report a case of SCC on his left index for three years. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101661DOI Listing

Ulcerative Squamous Eyelid Papilloma: A Rare Presentation.

J Ophthalmic Vis Res 2019 Oct-Dec;14(4):509-512. Epub 2019 Oct 24.

Department of Pathology, UP University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India.

Purpose: To highlight the importance of histopathological evaluation of a lid mass to prognosticate the disease. We report a case of ulcerative squamous cell papilloma with clinical features suggesting malignancy.

Case Report: A 65-year-old man presented with a rapidly enlarging mass in the left upper eyelid, with clinical features suggesting a squamous cell carcinoma. Read More

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http://dx.doi.org/10.18502/jovr.v14i4.5463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825690PMC
October 2019

Human papillomavirus in ocular malignant tumours: a study from a tertiary eye care centre in North India.

Can J Ophthalmol 2019 12 16;54(6):688-693. Epub 2019 Apr 16.

Ocular Oncology Service, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences New Delhi, India.

Objective: The present study aims to detect the presence of human papillomavirus (HPV) in ocular malignant tumours, including retinoblastoma, eyelid squamous cell carcinoma (SCC), and sebaceous gland carcinoma (SGC), in the North Indian population.

Design: Prospective observational non randomized study.

Participants: In this study, 142 prospective cases of ocular malignant tumours (retinoblastoma, SGC, and SCC) were included. Read More

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http://dx.doi.org/10.1016/j.jcjo.2019.03.001DOI Listing
December 2019

[Does orbital exenteration still has a place in 2019?]

J Fr Ophtalmol 2020 Feb 9;43(2):152-174. Epub 2019 Dec 9.

Service de chirurgie oncologique cervico-faciale, centre Antoine Lacassagne, 06189 Nice, France.

Introduction: Orbital exenteration is a radical anatomically and psychologically disfiguring procedure. It is mostly performed for management of orbital cancers or cancers with orbital involvement. The lack of benefit in terms of overall survival and the development of new molecular therapies (targeted therapies, immunotherapy) in recent years leads us to question its use. Read More

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http://dx.doi.org/10.1016/j.jfo.2019.04.021DOI Listing
February 2020

Giant Squamous Cell Papilloma of the Eyelid-Diagnostic and Therapeutic Challenges.

Case Rep Ophthalmol Med 2019 29;2019:5830493. Epub 2019 Oct 29.

Department of Ophthalmology, University of Szeged, Szeged, Hungary.

Squamous cell papilloma (SCP) is generally a human papillomavirus (HPV) induced exophytic or endophytic proliferation on the surface of the skin, oral cavity, larynx, esophagus, cervix, vagina, and anal canal. The endophytic type SCP can cause differential diagnostic difficulties with keratoacanthoma, inverted follicular keratosis, and squamous cell carcinoma; however, these lesions are not associated with HPV infection. The authors present a female patient who noticed an extremely rapidly growing tumor destructing the left lower eyelid. Read More

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http://dx.doi.org/10.1155/2019/5830493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875255PMC
October 2019

Mohs Surgery for Periocular Tumors.

Dermatol Surg 2019 12;45 Suppl 2:S70-S78

Total Skin and Beauty Dermatology Center, Birmingham, Alabama.

Background: Skin cancers of the periorbital area present unique challenges to Mohs surgeons.

Objective: The need for precise and high-quality Mohs micrographic surgery (MMS) is paramount because of the complex anatomy, vital structures, and potential threat to vision.

Methods: A thorough comprehension of anatomy is essential to help predict tumor behavior and ensure successful outcomes for patients. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002254DOI Listing
December 2019

Sensitivity and specificity of frozen section diagnosis in orbital and adnexal malignancies.

Indian J Ophthalmol 2019 12;67(12):1988-1992

Department of Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: To analyze the diagnostic accuracy of frozen section in orbital and adnexal malignancies.

Methods: A total of 55 cases between January 2006 and December 2011 for which intraoperative frozen section was performed for various orbital and adnexal lesions were included in the study. The frozen section diagnosis was compared with the permanent section diagnosis. Read More

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http://dx.doi.org/10.4103/ijo.IJO_2096_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896554PMC
December 2019

[A clinicopathological classification analysis of ocular mass lesions in 7 910 cases].

Zhonghua Yan Ke Za Zhi 2019 Nov;55(11):847-853

Department of Ophthalmology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.

To investigate the anatomical region, histopathological classification and histogensis distribution of ocular mass lesions in South China. Retrospective cases study. The clinical and pathological data of 7 910 samples with ocular (adnexal) tumors or proliferative lesions which were examined from January 2000 to May 2018 were retrospectively retrieved. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.11.011DOI Listing
November 2019

[Modified meibography in malignant eyelid tumors of epithelial origin].

Vestn Oftalmol 2019 ;135(5. Vyp. 2):141-149

Lomonosov Moscow State University, Faculty of Fundamental Medicine, 1 Leninskie Gory, Moscow, Russian Federation, 119991.

Introduction: Eyelid tumors can be diagnosed using various diagnostic techniques. However, capability of existing methods for determining the type and margins of the tumor at the preoperative stage remains insufficiently studied.

Purpose: To improve the noncontact infrared meibography technique and determine its diagnostic capabilities for studying structural changes in meibomian glands in malignant eyelid tumors of epithelial origin. Read More

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http://dx.doi.org/10.17116/oftalma2019135052141DOI Listing
November 2019

Conjunctival Benign Fibrous Histiocytoma in a 57-year-old man.

Rom J Ophthalmol 2019 Jul-Sep;63(3):273-276

OphtalmoEsterel, Saint-Raphaël, France.

To report a case of benign fibrous histiocytoma of the conjunctiva involving the cornea, an uncommon ocular surface tumor. A 57-year-old patient came in our service complaining of a progressively enlarging conjunctival mass temporally to the limbus and invading the adjacent cornea of the left eye. The approach consisted in surgical excision followed by cryotherapy on the edges and on the base of the excision site and amniotic membrane patch reconstruction of the ocular surface defect. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820492PMC
December 2019
1 Read

Usefulness of Topical Interferon Alpha-2b Eye Drop as an Adjunctive Therapy Following Surgical Resection in Ocular Surface Squamous Neoplasia.

In Vivo 2019 Nov-Dec;33(6):2211-2215

Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Aim: To report the clinical course of patients with ocular surface squamous neoplasia treated with topical interferon α-2b (IFNα-2b) after local excision of the tumor.

Patients And Methods: This study enrolled four consecutive Japanese patients comprising one eye with conjunctival carcinoma in situ, and three eyes with squamous cell carcinoma (SCC) diagnosed histopathologically. All of them initially visited Hokkaido University Hospital in 2016. Read More

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http://dx.doi.org/10.21873/invivo.11724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899090PMC

[Conjunctival malignancies].

Ophthalmologe 2019 Oct;116(10):989-1004

Klinik für Augenheilkunde Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland.

Conjunctival malignancies are rare. However, some of these tumors are among the most aggressive malignancies in ophthalmology and require radical forms of therapy that may lead to blindness or loss of the ipsilateral eye and tumor-associated death. The most relevant primary conjunctival malignancies for oncologists are squamous cell carcinoma, malignant melanoma and malignant lymphoma. Read More

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http://dx.doi.org/10.1007/s00347-019-00978-6DOI Listing
October 2019
2 Reads

Presurgical Curettage Improves Accuracy for Nonmelanoma Skin Cancer Excision.

J Cutan Med Surg 2019 Nov/Dec;23(6):617-623. Epub 2019 Aug 17.

Division of Dermatologic Surgery, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Background: Presurgical curettage before nonmelanoma skin cancer surgery may help delineate tumor subclinical extensions.

Objective: To determine histologically whether presurgical curettage appropriately or inappropriately changes excision specimen size.

Materials And Methods: One hundred fifty consecutive nonmelanoma skin cancers treated with Mohs micrographic surgery. Read More

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http://journals.sagepub.com/doi/10.1177/1203475419871048
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http://dx.doi.org/10.1177/1203475419871048DOI Listing
August 2019
5 Reads
0.714 Impact Factor

Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study.

Med Arch 2019 Jun;73(3):209-212

Clinic for Ophthalmology, University Clinical Center Tuzla, Bosnia and Herzegovina.

Introduction: To the best of our knowledge, this is the first study about malignant eyelid tumors in the region of Tuzla, Bosnia and Herzegovina, and it shows similar results comparing with other countries (the annual incidence of eyelid tumors in Tuzla region is about 3.73/100 000 population). Malignant eyelid tumors are relatively uncommon, but potentially fatal disease. Read More

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http://dx.doi.org/10.5455/medarh.2019.73.209-212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643352PMC
June 2019
12 Reads

Oncological and aesthetic outcome following surgical management of orbito-palpebral skin cancers: A retrospective study of 132 patients.

J Craniomaxillofac Surg 2019 Oct 16;47(10):1577-1582. Epub 2019 Jul 16.

Department of Plastic, Reconstructive and Maxillo-Facial Surgery, Henri-Mondor Hospital, AP-HP, Creteil, France.

Background: The incidence of facial skin cancers continues to rise, with major studies on their impacts still lacking in the literature. This study reports on the oncological and aesthetic results following surgical management of an orbito-palpebral skin cancer.

Methods: This retrospective, monocentric study included patients treated for a non-melanoma skin cancer of the eyelid and orbit. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10105182193034
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http://dx.doi.org/10.1016/j.jcms.2019.07.015DOI Listing
October 2019
2 Reads

Orbital Exenteration: A 23-year Report.

Korean J Ophthalmol 2019 Aug;33(4):366-370

Ophthalmic Plastic and Reconstructive Surgery Unit, Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: Orbital exenteration is a psychologically and anatomically disfiguring procedure which indicated in some patients with malignant or progressive diseases of orbital and periorbital area. In this study, we reviewed 176 patients that underwent orbital exenteration.

Methods: This was a retrospective study of medical records from all patients who underwent orbital exenteration from March 1991 to March 2014 in oculoplastic department at an eye care center. Read More

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http://dx.doi.org/10.3341/kjo.2018.0052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685828PMC
August 2019
2 Reads

Significance of Angiogenic Growth Factors in Bovine Ocular Squamous Cell Carcinoma.

J Comp Pathol 2019 Jul 22;170:60-69. Epub 2019 Jun 22.

Department of Surgery, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.

Bovine ocular squamous cell carcinoma (BOSCC) is the most common and economically significant neoplasm of the eye in cattle. This study investigated the role of angiogenic growth factors in the pathogenesis of BOSCC. Eighteen cases of BOSCC were classified histopathologically according to the degree of differentiation. Read More

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http://dx.doi.org/10.1016/j.jcpa.2019.05.008DOI Listing
July 2019
1 Read

Interferon Alfa 2b for Ocular Surface Squamous Neoplasia: Factors Influencing the Treatment Response.

Semin Ophthalmol 2019 1;34(7-8):465-472. Epub 2019 Aug 1.

Mark Nathaniel Thadikonda and Vijayamma Nannepaga Centre for Eye Care Education and Ophthalmic Biophysics (AM), L V Prasad Eye Institute, Hyderabad, India.

Purpose: To study the factors influencing the response to treatment with interferon alfa 2b (IFN) in ocular surface squamous neoplasia (OSSN)Methods: Retrospective study of 91 patientsResults: The mean age at presentation of patients with OSSN was 58 years (median, 60 years; range, 21 to 83 years). The mean number of clock hours of conjunctiva/cornea/limbus involvement by the tumor was 6 (median, 6; range, 1 to 12). The mean duration of topical IFN was 3 months (median, 3 months; range, 1 to 6 months) and the mean number of subconjunctival injections of IFN was 2 (median, 2; range, 0 to 6), till complete tumor regression or initiation of alternate treatment. Read More

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http://dx.doi.org/10.1080/08820538.2019.1648691DOI Listing
January 2020
3 Reads
1.196 Impact Factor

Regression of Sebaceous Carcinoma of the Eyelid after a Small Incisional Biopsy: Report of Two Cases.

Ocul Oncol Pathol 2019 Jun 2;5(4):252-257. Epub 2018 Nov 2.

Department of Ophthalmology, University of Toronto, Toronto, Ontario, Canada.

Purpose: To report 2 cases of regression of sebaceous carcinoma of the eyelid after a small incisional biopsy.

Methods: Clinical, imaging, and histopathological findings are presented, with a literature review on regressing ocular tumors.

Results: Our first patient was a 79-year-old man who presented with a 10-month history of progressive left upper eyelid ptosis caused by an eyelid tumor with orbital involvement and confirmed on magnetic resonance imaging. Read More

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http://dx.doi.org/10.1159/000490706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615332PMC
June 2019
4 Reads

Clinicopathologic Characteristics and Predictors Affecting Survival Outcome of Eyelid Malignancy.

J Craniofac Surg 2019 Jul;30(5):1516-1519

Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.

The aim of this study was to determine the clinicopathologic characteristics and evaluate the prognostic factors in eyelid malignancies. This was a retrospective, comparative, case series of 70 patients with eyelid malignancies. The mean age at diagnosis was 72. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005341DOI Listing
July 2019
8 Reads

Surgical Feasibility of Curtler-Beard Reconstruction for Large Upper Eyelid Defect.

J Craniofac Surg 2019 Oct;30(7):2181-2183

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Purpose: To report long-term surgical outcomes of Cutler-Beard reconstructive surgery in patients with large full-thickness upper eyelid defects following malignant tumor excision.

Methods: The medical records of 5 consecutive patients with full-thickness upper eyelid defects following tumor resection who underwent Cutler-Beard surgery were reviewed retrospectively between April 2005 and November 2018. Surgical procedure comprises 2 stages: first, complete tumor resection followed by bridged full-thickness lower eyelid advancement flap; second, separation of the closed eyelid with eyelid margin repair 7 to 9 weeks later. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005732DOI Listing
October 2019
12 Reads
0.676 Impact Factor

Periocular basal cell carcinoma: demographic, clinical, histological and immunohistochemical evaluation of a series of 39 cases.

Rom J Morphol Embryol 2019 ;60(1):77-86

Department of Neurosurgery, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania; Department of Anatomy, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania;

Background: Basal cell carcinoma (BCC) is the most frequent malignant epithelial tumor of the periocular area. The clinical and histological classification of periocular basal cell carcinoma (pBCC) is essential in order to establish the risk of recurrence and to compare the results of the treatment. Until now, there is no unitary histological classification of pBCC. Read More

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January 2020
6 Reads

The burden of squamous cell carcinoma of the conjunctiva in Africa.

Cancer Epidemiol 2019 08 27;61:150-153. Epub 2019 Jun 27.

CTSU, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7FL, United Kingdom; African Cancer Registry Network, 267 Banbury Road, Oxford OX2 7HT, United Kingdom.

Squamous cell carcinoma of the conjunctiva (SCCC) is a relatively common cancer in Africa, although its precise incidence and geographic distribution have not been previously systematically studied.

Methods: Using the methods employed to produce national estimates of cancer incidence for the "Globocan" series of the International Agency for Research on Cancer, along with detailed information on cancer incidence by histological subtype from cancer registries in Africa, we estimate the numbers and rates of incidence by sex, age group, country and region of Africa.

Results: We estimate that the number of new cases occurring in 2018 to be about 6 200, with all but about 50 in sub Saharan Africa, and 55% in females. Read More

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http://dx.doi.org/10.1016/j.canep.2019.06.007DOI Listing
August 2019
3 Reads

Simultaneous squamous cell carcinoma and malignant melanoma of the conjunctiva in a teenager with xeroderma pigmentosum: Case report.

Indian J Ophthalmol 2019 07;67(7):1190-1192

Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Federal University of São Paulo, Rua Botucatu, 822, São Paulo, Brazil.

Xeroderma pigmentosum (XP) is an autosomal recessive disease with ophthalmic, dermatologic, and neurologic manifestations. Ophthalmological changes are described in up to 100% of XP patients. We report a young XP patient that presented with bilateral conjunctival masses. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1106_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611241PMC
July 2019
8 Reads

Merkel Cell Carcinoma of the Eyelids (Clinical-Histological Study).

Cesk Slov Oftalmol 2019 ;74(5):198-205

Aim: To get acquainted with the issues of Merkel cell carcinoma (MCC) when the eyelid is affected and with its surgical solution.

Materials: MCC of the right upper eyelid was at the Department of Ophthalmology in the Faculty Hospital Královské Vinohrady in Prague (Czech Republic, EU) in 1998 woman 78 year. Another cases of the MCC on the left upper eyelid were observed in two women aged 48 and 67 years and they were pick up in a retrospective study covered 1033 operated tumors eyelids years 2007 - 2015. Read More

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http://dx.doi.org/10.31348/2018/5/5DOI Listing
June 2019
4 Reads

Reconstruction of exenteration socket with Integra dermal substitute and skin graft.

J Fr Ophtalmol 2019 Sep 14;42(7):746-752. Epub 2019 Jun 14.

Département d'ophtalmologie, Mercy Hospital, Regional Hospital Center of Metz-Thionville, 1, allée du château, CS 45001, 57085 Metz Cedex 03, France. Electronic address:

The authors report their experience with the use of Integra dermal substitute, in combination with a thin skin graft, following an orbital exenteration. The clinical case described relates to a 42-year-old gentleman with an ulcerative retractile lesion of the right lower eyelid. Histopathological examination diagnosed a moderately differentiated epidermoid carcinoma infiltrating the orbit. Read More

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http://dx.doi.org/10.1016/j.jfo.2019.03.023DOI Listing
September 2019
6 Reads

Predictive Value of Preoperative Periocular Skin Cancer Measurements for Final Mohs Defect Size.

Ophthalmic Plast Reconstr Surg 2019 Nov/Dec;35(6):604-608

Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.

Purpose: To evaluate the relationship between pre-Mohs skin cancer lesion measurements with the post-Mohs defect size in order to most accurately estimate post-Mohs defect size.

Methods: This is a retrospective analysis of patients who underwent Mohs excision by one of 3 Mohs surgeons followed by reconstruction for basal cell carcinoma or squamous cell carcinoma of the eyelid. The study included all patients from January 2011 to May 2018 operated on by a single oculoplastic surgeon (R. Read More

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http://Insights.ovid.com/crossref?an=00002341-900000000-9828
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http://dx.doi.org/10.1097/IOP.0000000000001421DOI Listing
January 2020
9 Reads

Advances in Immunotherapy and Periocular Malignancy.

Semin Ophthalmol 2019 9;34(4):327-333. Epub 2019 Jun 9.

a Ophthalmic Plastic Surgery , Massachusetts Eye and Ear Infirmary , Boston , MA , USA.

Immunotherapy has significantly advanced the field of oncology in recent decades. Understanding normal immunosurveillance, as well as the ways in which tumor cells have evolved to evade it, has provided the knowledge for development of drugs that allow one's own immune system to target and destroy malignant cells (immunotherapy). Cutaneous malignancies are particularly sensitive to this class of drugs. Read More

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http://dx.doi.org/10.1080/08820538.2019.1620813DOI Listing
July 2019
8 Reads
1.196 Impact Factor

Lower eyelid reconstruction with pericranium graft and Mustarde flap.

Arch Soc Esp Oftalmol 2019 Oct 3;94(10):514-517. Epub 2019 Jun 3.

Departamento de Oculoplastia y Órbita, Institut Català de Retina, Barcelona, España. Electronic address:

We report the case of a 68-year-old man with a left lower eyelid basal cell carcinoma with squamous differentiation. Resection was performed under frozen section technique and the defect (inner canthus, two thirds of the lower eyelid and 2.5cm of the cheek) reconstructed 2 days after surgery in a single surgical operation: posterior lamella with pericranial graft and anterior lamella with Mustarde flap. Read More

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http://dx.doi.org/10.1016/j.oftal.2019.04.011DOI Listing
October 2019
20 Reads

Use of High-Resolution Optical Coherence Tomography in the Surgical Management of Ocular Surface Squamous Neoplasia: A Pilot Study.

Am J Ophthalmol 2019 10 1;206:17-31. Epub 2019 Jun 1.

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA; Florida Lions Ocular Pathology Laboratory, Miami, Florida, USA.

Purpose: To evaluate whether high-resolution optical coherence tomography (HR-OCT) can detect histologic tumor margins of ocular surface squamous neoplasia (OSSN).

Methods: Eight eyes of 8 patients with OSSN undergoing excision were studied prospectively. Immediately before surgery, the tumor was imaged using commercially available HR-OCT to identify the conjunctival margins of the neoplastic lesion. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885111PMC
October 2019
6 Reads

The effect of topical voriconazole on conjunctiva in rats as revealed by histopathology and immunohistochemistry.

J Chemother 2019 Sep 29;31(5):267-273. Epub 2019 May 29.

Department of Ophthalmology, Ege University School of Medicine , Bornova , Izmir.

The aim of this study was to evaluate the effects of topical voriconazole with histopathological and immunohistochemical analysis of the conjunctiva in rats. Twenty-eight Sprague Dawley rats were divided into four groups as two study (S1, S2) and two control (C1, C2). Voriconazole was instilled four times daily to S1, S2 rats. Read More

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http://dx.doi.org/10.1080/1120009X.2019.1603798DOI Listing
September 2019
16 Reads

[Clinical analysis of conjunctival papilloma].

Authors:
X S Meng X W Liu

Zhonghua Yan Ke Za Zhi 2019 May;55(5):369-373

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

To summarize and analyze the clinical manifestation of conjunctival papilloma, its relationship with human papillomavirus (HPV) infection and the recurrence after the combination of operation and pharmacotherapy. A retrospective case series study. Analysis of 40 patients (41 eyes) with conjunctival papilloma treated at Peking Union Medical College Hospital from January 2008 to June 2018 was performed. Read More

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http://www.chinadoi.cn/portal/mr.action?doi=10.3760/cma.j.is
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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.05.011DOI Listing
May 2019
7 Reads

Management of Ocular Surface Squamous Neoplasia with Topical and Intralesional Interferon Alpha 2B in Mexicans.

Nepal J Ophthalmol 2018 Jul;10(20):143-150

nstituto de Oftalmología Fundación de Asistencia Privada Conde de Valenciana.

Introduction: Ocular surface squamous neoplasia (OSSN) is the most common nonpigmented ocular surface neoplasm and it can originate from the conjunctiva and/ or corneal epithelium. Since the rate of recurrence after surgical excision is high, chemotherapeutic and immunotherapeutic agents such as interferon alpha-2b (IFN α-2b) have been used for its treatment.

Objective: Our objective is to describe the demographic variables of patients with OSSN treated with IFN α-2b and to describe the outcomes of its use in Mexican patients, treated between 2011 and 2017 at Instituto de Oftalmología Fundación Conde de Valenciana. Read More

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https://www.nepjol.info/index.php/NEPJOPH/article/view/18574
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http://dx.doi.org/10.3126/nepjoph.v10i2.18574DOI Listing
July 2018
15 Reads

Malignant Eyelid Tumors in India: A Study of 536 Asian Indian Patients.

Ocul Oncol Pathol 2019 Apr 13;5(3):210-219. Epub 2018 Sep 13.

Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, India.

Purpose: To study the proportion of eyelid malignant tumors in an Asian Indian population and to review their clinical features and outcomes.

Methods: This is a retrospective study of 536 patients.

Results: The mean age at presentation with eyelid malignancy was 58 years. Read More

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http://dx.doi.org/10.1159/000491549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489076PMC
April 2019
12 Reads

Transnasal frontal intersinus septum takedown for frontal sinus pyocele.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Sep 22;136(4):321-323. Epub 2019 Apr 22.

Department of Otorhinolaryngology - Head and Neck Surgery, Changi General Hospital, 2 Simei St 3, Singapore 529889, Singapore. Electronic address:

Introduction: The open frontal intersinus septum takedown (FISST) technique was first described in 1976. We describe our experience with an endoscopic transnasal approach to manage a frontal sinus pyocele arising from an obstructed frontal sinus outflow tract due to anterolateral thigh flap reconstruction of a maxillectomy defect.

Case Report: A 40-year-old lady experienced upper eyelid swelling and purulent nasal discharge 3 weeks after undergoing a left extended medial maxillectomy with free anterolateral thigh flap reconstruction. Read More

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http://dx.doi.org/10.1016/j.anorl.2018.06.008DOI Listing
September 2019
8 Reads

Keratinocyte cancer excisions in Australia: Who performs them and associated costs.

Australas J Dermatol 2019 Nov 22;60(4):294-300. Epub 2019 Apr 22.

Department of Population Health, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

Background/objective: To describe the clinical settings in which keratinocyte cancers are excised in Queensland and describe the types of practitioners who excise them; to examine costs; and to identify predictors of hospital admission.

Methods: We used linked data for participants from the QSkin study (n = 43 794), including Medicare claims and Queensland hospital admissions relating to treatment episodes for incident keratinocyte cancers from July 2011 to June 2015. We used multinomial logistic regression to measure associations between demographic and clinical characteristics and treatment setting. Read More

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http://dx.doi.org/10.1111/ajd.13056DOI Listing
November 2019
4 Reads

Malignant transformation of a conjunctival keratoacanthoma requiring enucleation.

Clin Ter 2019 Mar-Apr;170(2):e81-e83

Ophthalmology Department. Hospital General. Granollers, España.

Purpose: We report a rare case of rapid transformation of a conjunctival keratoacanthoma (KA) into a highly aggressive squamous cell carcinoma requiring enucleation. To our knowledge, this is the second such case reported in the literature.

Methods: Case report. Read More

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http://dx.doi.org/10.7417/CT.2019.2113DOI Listing
June 2019
4 Reads

National incidence of eyelid cancer in Ireland (2005-2015).

Eye (Lond) 2019 10 11;33(10):1534-1539. Epub 2019 Apr 11.

Sligo University Hospital, Sligo, Ireland.

Aims: We report on the incidence of cutaneous eyelid tumours in Ireland over the 11-year-period from 2005 to 2015, we identify associations between demographic factors and cutaneous eyelid tumour risk.

Methods: Skin cancers, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), melanoma, and other cancers, located on the eyelid or canthus according to ICD-10 coding, as registered by the National Cancer Registry of Ireland (NCRI), were captured from the period 2005 to 2015. Age standardised rates (ASR) were calculated according to the European Standard Population (2013). Read More

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http://www.nature.com/articles/s41433-019-0437-8
Publisher Site
http://dx.doi.org/10.1038/s41433-019-0437-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002498PMC
October 2019
19 Reads

Outcomes of Second Intention Healing of the Lower Eyelid Margin After Mohs Micrographic Surgery.

Dermatol Surg 2019 07;45(7):884-889

All authors are affiliated with Trieu Dermatology, Harvey, Louisiana and Derm Surgery Associates, Houston, Texas.

Background: Lower eyelid margin defects can be a reconstructive challenge. A possible alternative is second intention healing of the lower eyelid margin.

Objective: To determine the cosmetic outcomes and patient satisfaction of second intention healing of the lower eyelid margin after Mohs micrographic surgery (MMS). Read More

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http://dx.doi.org/10.1097/DSS.0000000000001951DOI Listing
July 2019
4 Reads