Dectin-1 expression by macrophages and related antifungal mechanisms in a murine model of Sporothrix schenckii sensu stricto systemic infection.
- Juliana Aparecida Jellmayer,
- Lucas Souza Ferreira,
- Francine Alessandra Manente,
- Amanda Costa Gonçalves,
- Marisa Campos Polesi,
- Alexander Batista-Duharte,
- Iracilda Zeppone Carlos
Microb Pathog 2017 Jun 20. Epub 2017 Jun 20.
Department of Clinical Analysis, Faculty of Pharmaceutical Sciences of Araraquara, São Paulo State University " Júlio de Mesquita Filho " - UNESP, Araraquara, SP, Brazil. Electronic address:
The available information about the role of Dectin-1 in sporotrichosis is scarce. Hence, we aimed to assess Dectin-1 expression by macrophages and the activation of some related antifungal mechanisms during the Sporothrix schenckii sensu stricto infection as a first attempt to elucidate the role of this receptor in sporotrichosis. Balb/c mice were intraperitoneally infected with S. Read More