Clin Res Hepatol Gastroenterol 2021 Apr 27:101714. Epub 2021 Apr 27.
The Department of Internal, Occupational Diseases and Rheumatology, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya st., Moscow, 119991, Russia; The Department of Internal Diseases, Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, 27-1 Lomonosov prospect, Moscow, 119192, Russia.
Background: Previous short-term studies have reported on liver function improvements and delisting among liver transplantation (LT) candidates with hepatitis C virus (HCV) and decompensated liver cirrhosis after successful antiviral therapy. This study aimed to evaluate the long-term impact of HCV eradication on liver function, portal hypertension, probability of delisting, and clinical outcomes in patients awaiting LT.
Methods: Forty-five LT candidates with decompensated HCV cirrhosis were prospectively observed after HCV eradication by direct-acting antiviral therapy. Read More