6,210 results match your criteria Splenic Rupture

Porcine spleen as a model organ for blunt injury impact tests: An experimental and histological study.

Anat Histol Embryol 2022 Jun 25. Epub 2022 Jun 25.

European Centre of Excellence NTIS, Faculty of Applied Sciences, University of West Bohemia, Pilsen, Czech Republic.

The spleen is a large and highly vascularized secondary lymphatic organ. Spleen injuries are among the most frequent trauma-related injuries in the abdominal region. The aims of the study were to assess the volume fractions of the main splenic tissue components (red pulp, white pulp, trabeculae and reticular fibres) and to determine the severity of splenic injury due to the experimental impact test. Read More

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The Usual Presentation of an Unusual Case: Spontaneous Primary Splenic Cyst Rupture.

Cureus 2022 May 18;14(5):e25097. Epub 2022 May 18.

Internal Medicine, Saint Mary's Hospital, Waterbury, USA.

Acute abdominal pain is one of the most common reasons for emergency admissions. Even though initial differentials are wide, a physician is able to narrow them down with detailed history, careful physical examination, and appropriate laboratory tests along with imaging studies. Unfortunately, some of the cases do not have an established diagnosis despite multiple blood work and imaging studies in the emergency department. Read More

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Intra-abdominal Hemorrhage due to Splenic Vein Aneurysm Rupture Caused by Invasive Aspergillosis During Treatment for Advanced Non-small-cell Lung Cancer.

Intern Med 2022 Jun 21. Epub 2022 Jun 21.

Department of Respiratory Medicine, Seirei Hamamatsu General Hospital, Japan.

A 71-year-old man was admitted for left-sided chest pain. He had a history of diabetes, treatment with epidermal growth factor receptor-tyrosine kinase inhibitor for advanced non-small-cell lung cancer, and corticosteroid treatment for underlying lung diseases. Chest computed tomography showed consolidations in the bilateral lower lobes, and Aspergillus fumigatus was detected by bronchoscopy. Read More

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Splenic Artery Embolization and Splenectomy for Spontaneous Rupture of Splenic Hemangioma and Its Imaging Features.

Front Cardiovasc Med 2022 3;9:925711. Epub 2022 Jun 3.

Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China.

Background: Spontaneous splenic rupture (SSR) is a rare, often life-threatening, acute abdominal injury that requires immediate diagnosis and early treatment. SSR is mainly treated surgically or conservatively. A few cases of interventional embolization for SSRs have been reported. Read More

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Development of Wunderlich syndrome following a Russell's viper bite.

Toxicon 2022 Jun 9;215:11-16. Epub 2022 Jun 9.

School of Pharmacy, University of Reading, UK. Electronic address:

Snakebite envenomation is a high priority neglected tropical disease that predominantly affects rural communities living in developing countries. Due to myriad of complications including coagulopathies, neurotoxicity, nephrotoxicity and local tissue destruction, treating snakebite victims is a major challenge for clinicians. Russell's viper (Daboia russelii) is one of the 'Big Four' venomous snakes in India, and it is responsible for the most snakebite-induced deaths and disabilities. Read More

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Review spontaneous superior mesenteric artery aneurysm rupture following caesarean section: an uncommon event and review of current literature.

J Obstet Gynaecol 2022 Jun 10:1-3. Epub 2022 Jun 10.

Obstetrics and Gynecology Department, Izmir Katip Celebi University Atatürk Training and Research Hospital, İzmir, Turkey.

Pregnancy-related rupture of an arterial aneurysm is an unusual occurrence associated with an increased risk of morbidity and mortality. Splenic artery aneurysms are the most common (60%), followed by hepatic (20%), superior mesenteric (5.9%), coeliac (4%), ovarian, uterine, and renal (<2%) arteries during pregnancy. Read More

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Spontaneous splenic rupture from indeterminate dendritic cell proliferation: a case report.

J Surg Case Rep 2022 Jun 7;2022(6):rjac211. Epub 2022 Jun 7.

Pulmonology and Critical Care Medicine, MedStar Franklin Square Medical Center, Baltimore, MD, USA.

Spontaneous splenic rupture is a rare and life-threatening phenomenon, usually associated with an underlying infectious, inflammatory, hematological, neoplastic or rheumatologic condition. Indeterminate cell tumor is a rare neoplastic dendritic cell disorder that is poorly understood but shares immunophenotypic markers for Langerhans cells without Birbeck granules. A 73-year-old man presented with upper abdominal pain after an unwitnessed fall. Read More

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Mantle Cell Lymphoma With Non-traumatic Splenic Rupture Requiring Emergency Splenectomy.

Cureus 2022 May 2;14(5):e24675. Epub 2022 May 2.

Department of Surgery, Trumbull Regional Medical Center, Warren, USA.

Mantle cell lymphoma (MCL) is a type of non-Hodgkin (B-cell) lymphoma (NHL) with manifestations ranging from indolent to aggressive disease. This type of NHL is predominately found in western countries and affects men more often than women (M:F 2:1). The median age of diagnosis with the disease is around 60 years of age. Read More

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Splenic Laceration: A Rare Complication of Colonoscopy.

Cureus 2022 May 2;14(5):e24660. Epub 2022 May 2.

Pulmonary and Critical Care Medicine, University of Illinois College of Medicine at Peoria, Peoria, USA.

Splenic injury is usually seen with penetrating or blunt abdominal trauma. It is also one of the rare complications of colonoscopy. Various patient and procedural factors have been reported to increase the risk of this dreaded complication. Read More

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Robotic real-time vessel navigation using indocyanine green fluorescence for lymph node dissection along the left gastroepiploic vessels during robotic distal gastrectomy First experience.

J Minim Access Surg 2022 May 27. Epub 2022 May 27.

Department of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Sapporo, Japan.

Splenic infarction (SI) following gastrectomy is common; severe complications related to SI, such as splenic haemorrhage, abscess formation or rupture, can be fatal. To overcome these problems, we performed real-time vessel navigation using indocyanine green (ICG) fluorescence during robotic distal gastrectomy (RDG). The aim of study is to report the efficacy of robotic real-time vessel navigation for lymph node dissection (LND) along left gastroepiploic vessels (LGEVs). Read More

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Primary splenic lymphoma discovered on massive splenomegaly: A case report.

Int J Surg Case Rep 2022 May 27;94:107124. Epub 2022 Apr 27.

Department of General Surgery, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia; University Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.

Introduction And Importance: Malignant lymphoma occurs in all the systemic organs. Rarely, large B-cell lymphoma is located in the spleen, making the diagnosis difficult. Herein, we report a patient presenting with massive splenomegaly due to LBCL. Read More

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Maternal deaths in Australia from ruptured splenic artery aneurysms.

Aust N Z J Obstet Gynaecol 2022 Jun 2. Epub 2022 Jun 2.

Obstetrics and Gynaecology, Newcastle, New South Wales, Australia.

The rupture of a splenic artery aneurysm (SAA) in pregnancy is a highly lethal condition, but so rare, that most obstetricians would not encounter it during their career. In the seven official 'Maternal Deaths in Australia' reports, that covered 21 years from 1997 to 2017, among a total of 449 direct and indirect deaths, there were nine deaths (2%) from a ruptured SAA. These cases, and other cases from the literature and the Cochrane Library, are reviewed. Read More

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An argument for serial imaging in a rare case of splenic rupture secondary to complicated pancreatic pseudocyst in a rural patient.

Aust J Rural Health 2022 May 31. Epub 2022 May 31.

Department of General Surgery, Dubbo Base Hospital, Dubbo, NSW, Australia.

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Splenic rupture following lenograstim in post-autologous stem cell transplantation treated with emergency open splenectomy: a case report and literature review.

J Int Med Res 2022 May;50(5):3000605221095504

Oncohematology and BMT Unit, Mediterranean Institute of Oncology, Viagrande, Italy.

Granulocyte-colony stimulating factors (G-CSFs) are the cornerstone of peripheral blood stem cell mobilization and apheresis. However, splenic rupture following G-CSF treatment represents a serious and potentially fatal adverse event. Here, we report the case of a patient in their late 50s with severe pancytopenia post-autologous stem cell transplantation reinfusion suffering from splenic rupture after treatment with lenograstim. Read More

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Splenic artery transposition for reconstruction of a large hepatic artery aneurysm: A case report and literature review.

Int J Surg Case Rep 2022 Jun 16;95:107209. Epub 2022 May 16.

University of Tsukuba, Faculty of Medicine, Gastroenterological and Hepato-Biliary-Pancreatic Surgery, 1-1-1 Tennnodai, Tsukuba-city, Ibaraki-Ken 305-8575, Japan. Electronic address:

Introduction And Importance: Hepatic artery aneurysms (HAAs) are rare. Typical treatment options for HAAs are surgical resection and endovascular treatment but treatment choices remain controversial.

Case Presentation: A 65-year-old woman was rushed to our hospital suspected to have hemorrhage. Read More

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Splenic artery aneurysm in pregnancy: A systematic review.

Int J Gynaecol Obstet 2022 May 22. Epub 2022 May 22.

Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

Objective: Splenic artery aneurysms (SAA) are associated with significant maternal and fetal mortality when ruptured in pregnancy. However, there is no consensus on the optimal obstetric management of both ruptured and asymptomatic SAA. We aimed to evaluate risk factors, presentation, investigation, and management of SAA in pregnancy and puerperium. Read More

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Atraumatic splenic rupture in a child with COVID 19.

BMC Pediatr 2022 May 21;22(1):300. Epub 2022 May 21.

Medical University of Vienna, Vienna, Austria.

Background: The majority of children with COVID-19 have only minor symptoms or none at all. COVID-19, on the other hand, can cause serious illness in some children, necessitating hospitalization, intensive care, and invasive ventilation. Many studies have revealed that SARS-CoV-2 affects not only the respiratory system, but also other vital organs in the body. Read More

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A Primary Extraskeletal Osteosarcoma of the Spleen: Rare Case Report.

Front Oncol 2022 2;12:892943. Epub 2022 May 2.

Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China.

Extraskeletal osteosarcoma is a rare malignant soft-tissue sarcoma that is difficult to diagnose. Surgery is a common treatment, although chemotherapy and radiotherapy are also used. Patients at risk of bleeding can undergo embolization combined with resection. Read More

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Splenic artery embolization for spontaneous splenic rupture due to Babesiosis: a case report.

Radiol Case Rep 2022 Jul 5;17(7):2304-2308. Epub 2022 May 5.

Radiology Department, Norwalk Hospital, 34 Maple St, Norwalk, CT, USA.

Babesiosis incidence in the United States has been increasing with an 11% rise between 2018 and 2019 based on the latest CDC annual summary, reaching its highest ever reported incidence. This primarily tick-borne disease is particularly prevalent in New England. Despite predominantly nonspecific and at times subtle symptoms, life-threatening complications do occur. Read More

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Case Report: Hemodynamic Instability Caused by Splenic Rupture During Video-Assisted Thoracoscopic Lobectomy.

Front Surg 2022 22;9:900396. Epub 2022 Apr 22.

Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Background: Video-assisted thoracoscopic surgery (VATS) has been widely performed for patients with lung cancer. Splenic rupture after VATS lung procedures is a very rare and serious event.

Case Presentation: We reported a case with hemodynamic instability after left lower VATS lobectomy. Read More

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Atraumatic Splenic Rupture due to Chronic Myelomonocytic Leukemia Treated with Partial Splenic Artery Embolization.

Case Rep Oncol 2022 Jan-Apr;15(1):277-284. Epub 2022 Mar 21.

Department of Hematology/Oncology, Rocky Mountain Regional VA, Aurora, Colorado, USA.

Splenic rupture can be categorized into two groups: traumatic and atraumatic. Traumatic rupture is frequently associated with blunt abdominal trauma, while atraumatic splenic rupture (ASR) is more uncommon and has been associated with both benign and malignant hematological disorders. In general, most cases of splenic rupture are managed with splenectomy, which carries significant mortality and morbidity; more recently, splenic artery embolization (SAE) has become a mainstay of management particularly after traumatic rupture. Read More

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Pathological and ATR-FTIR spectral changes of delayed splenic rupture and medical significance.

Spectrochim Acta A Mol Biomol Spectrosc 2022 Oct 21;278:121286. Epub 2022 Apr 21.

Department of Forensic Pathology, College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China. Electronic address:

Traumatic delayed splenic rupture often follows by a "latent period" without typical symptoms after injury. During this period, though there are no obvious symptoms, the injury is still present and changing. In this study, we constructed an SD rat model of delayed splenic rupture; evaluated the model by HE staining, Perl's staining, Masson trichrome staining and immunohistochemical staining; observed the pathological changes of spleen tissue in delayed splenic rupture at different times after splenic injury; we found that pathological change of injured tissues were different from non-injured, and has phases-change patterns, it can be roughly divided into three phases: 2-7 d, 10-14 d, and 18-28. Read More

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October 2022

Atraumatic spontaneous splenic rupture in a female COVID-19 patient.

J Osteopath Med 2022 May 6. Epub 2022 May 6.

Medical College of Georgia, Augusta University, Augusta, GA, USA.

Coronavirus disease (COVID-19), an infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has severely ravaged the world since the end of 2019. Although most cases range from mild to severe with primarily respiratory symptoms, there have been some unusual clinical presentations, one of which is described in this case report. A 30 year-old woman with no significant medical history presented to the emergency department (ED) in October 2020 with sudden onset of severe left upper and lower abdominal pain. Read More

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Management of splenic and/or hepatic pseudoaneurysm following abdominal trauma in pediatric patients.

Cir Pediatr 2022 Apr 1;35(2):80-84. Epub 2022 Apr 1.

Pediatric Surgery Department. Parc Taulí Healthcare Corporation Consortium. Sabadell, Barcelona (Spain).

Introduction: Splenic and hepatic pseudoaneurysm (PA) is a rare arteriovenous injury that may occur following abdominal trauma. The most frequent complication of PA is late rupture, which can lead to hemodynamic instability. The objective of this study was to describe our experience in the management of visceral PA. Read More

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Acute Cytomegalovirus Infection Associated With Splenic Infarction: A Case Report and Review of the Literature.

Cureus 2022 Mar 22;14(3):e23404. Epub 2022 Mar 22.

General and Colorectal Surgery, University of New South Wales, St. Vincent's Hospital, Sydney, AUS.

Splenic infarction associated with acute cytomegalovirus infection (CMV) in immunocompetent patients was initially described as a very rare occurrence but has been reported in recent years with increasing frequency. Many cases undergo multiple investigations only to leave acute CMV as the likely cause. There is a risk of splenic rupture and, although this complication is rare, fatalities have occurred. Read More

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Spontaneous rupture of spleen in a patient with COVID-19 disease: case report and review of the literature.

J Surg Case Rep 2022 Apr 23;2022(4):rjac124. Epub 2022 Apr 23.

Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Coronavirus disease 2019 (COVID-19) has been associated with multisystemic complications and thrombotic events including pulmonary embolism and deep venous thrombosis. Splenic rupture has been recently reported as a complication in patients with COVID-19, however, the number of cases is limited and the mechanism is still not clearly understood. We present a case of spontaneous splenic rupture secondary to COVID-19 disease. Read More

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Ultrasound-Guided Compression Method Effectively Counteracts Russell's Viper Bite-Induced Pseudoaneurysm.

Toxins (Basel) 2022 04 6;14(4). Epub 2022 Apr 6.

School of Pharmacy, University of Reading, Reading RG6 6UB, UK.

Russell's viper (), one of the 'Big Four' venomous snakes in India, is responsible for the majority of snakebite-induced deaths and permanent disabilities. Russell's viper bites are known to induce bleeding/clotting abnormalities, as well as myotoxic, nephrotoxic, cytotoxic and neurotoxic envenomation effects. In addition, they have been reported to induce rare envenomation effects such as priapism, sialolithiasis and splenic rupture. Read More

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Splenic artery aneurysm rupture in pregnancy: challenges in diagnosis and the importance of multidisciplinary management.

BMJ Case Rep 2022 Apr 20;15(4). Epub 2022 Apr 20.

University of Bristol, Bristol, UK.

This case of acute rupture of a splenic artery aneurysm in a patient 35 weeks pregnant demonstrates the difficulties in diagnosis and importance of multidisciplinary team management for surgical emergencies in pregnancy. A women in her early 30s presented at 35 weeks pregnant with sudden onset of severe epigastric pain and shortness of breath and was found to be tachycardic with a raised lactate. Differentials included a possible vascular event or pulmonary embolism. Read More

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Treatment with sorafenib plus camrelizumab after splenectomy for primary splenic angiosarcoma with liver metastasis: A case report and literature review.

World J Clin Cases 2022 Mar;10(9):2818-2828

Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.

Background: Primary splenic angiosarcoma (PSA) is an extremely rare and aggressive mesenchymal malignancy with high metastatic potential and a poor prognosis. There are no established treatment guidelines for PSA, even for adjuvant therapy. This rare case may provide a reliable therapeutic regime for a better prognosis. Read More

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Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature.

Clin J Gastroenterol 2022 Apr 16. Epub 2022 Apr 16.

Division of Gastroenterology and Hepatology, Department of Internal Medicine (Omori), School of Medicine, Faculty of Medicine, Toho University, 6-11-1, Omorinishi, Ota-ku, Tokyo, 143-8541, Japan.

Left-side portal hypertension (LSPH) is caused by isolated obstruction of the splenic vein and is associated with esophagogastric varices that extend from the lower esophagus to the greater curvature of the gastric body. Here, we report on a 74-year-old man with a pancreatic neuroendocrine neoplasm (NEN) in the pancreatic tail with multiple liver metastases. We decided that partial splenic embolization (PSE) was the best course of treatment to prevent rupture of the gastric varices, which were classified as markedly enlarged, nodular, or tumor-shaped and showed erosion of the mucosa. Read More

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