1,966 results match your criteria Splenic Infarct


Splenic Infarct After Warfarin Overdose Treatment; Is it coincidence or complication?

Authors:
Gökhan Yilmaz

Ann Vasc Surg 2019 Apr 19. Epub 2019 Apr 19.

Specialist, Emergency Medicine Clinic, Kayseri Training and Research Hospital, Kayseri, Turkey. Electronic address:

The Splenic infarct is a rare clinical condition seen in the emergency department and can mimic acute abdomen. Hematologic, vascular and thromboembolic events are considered in the etiology. Treatment options are varying between symptomatic treatment and splenectomy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08905096193026
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http://dx.doi.org/10.1016/j.avsg.2019.02.012DOI Listing
April 2019
1 Read

Splenic necrosis requiring ultrasound-guided drainage following meningococcal septicaemia.

Oxf Med Case Reports 2019 Mar 29;2019(3):omz020. Epub 2019 Mar 29.

Department of Emergency Medicine, St George Hospital, St George QLD, Australia.

Splenic necrosis is an extremely rare complication in the context of meningococcal septicaemia and disseminated intravascular coagulopathy. We present the case of a previously healthy 22-year-old male who was diagnosed and treated for meningococcal septicaemia. He represented 4 days following discharge with significant splenic necrosis and associated abscess formation despite previously unremarkable imaging on his first admission. Read More

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http://dx.doi.org/10.1093/omcr/omz020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440269PMC

Robotic spleen-preserving splenic hilar lymph node dissection during total gastrectomy for gastric cancer.

Surg Endosc 2019 Apr 3. Epub 2019 Apr 3.

Department of Surgery, Yonsei University College of Medicine, 50-1 Yonsei-ro Seodaemun-gu, Seoul, 03722, Republic of Korea.

Background: Robotic system may have potential advantages to facilitate the technically challenging splenic hilar lymphadenectomy during gastrectomy for gastric cancer. However, robotic spleen-preserving splenic hilar lymphadenectomy is performed infrequently not only because of the limited availability of the robot but also because of its technical difficulty. In this study, we describe our technique of performing robotic spleen-preserving splenic hilar lymphadenectomy in detail to facilitate wider application and present operative outcomes and the follow-up results of the procedure. Read More

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http://dx.doi.org/10.1007/s00464-019-06772-4DOI Listing
April 2019
1 Read

Splenosis of the abdomen and pelvis complicated by torsion of a splenic implant clinically mimicking an acute bowel ischemia.

BJR Case Rep 2018 Dec 24;4(4):20180024. Epub 2018 May 24.

Department of General and Emergency Surgery, Ca' Granda IRCSS Maggiore Policlinico Hospital Foundation Trust, Milan, Italy.

We present a case of splenosis of the abdomen and pelvis complicated by torsion of a splenic implant in a young female patient clinically mimicking an acute bowel ischemia. Splenosis is a benign condition defined as heterotopic auto-transplantation of splenic tissue throughout different body areas. It may occur after rupture of the spleen, either traumatic or secondary to surgical procedures. Read More

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http://dx.doi.org/10.1259/bjrcr.20180024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438399PMC
December 2018
1 Read

Partial Splenic Embolization is a Safe and Effective Alternative in the Management of Portal Hypertension in Children.

J Pediatr Gastroenterol Nutr 2019 Mar 18. Epub 2019 Mar 18.

Department of Pediatrics, Columbia University Medical Center, New York, NY.

Objective: There are multiple approaches to manage the clinical complications of portal hypertension (PHTN) to treat/prevent spontaneous hemorrhage by mitigating thrombocytopenia. No single approach is ideal for all patients given the heterogeneity of this population. Our goal was to determine whether partial splenic embolization (PSE) was safe and effective in the pediatric population. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002332DOI Listing
March 2019
5 Reads

Granulocyte Colony Stimulating Factor (G-CSF) Induced Splenic Infarction in Breast Cancer Patient Treated with Dose-Dense Chemotherapy Regimen.

Case Rep Oncol Med 2019 13;2019:8174986. Epub 2019 Feb 13.

King Abdullah International Medical Research Center, Saudi Arabia.

Introduction: Granulocyte colony-stimulating factor (G-CSF) is commonly used for prevention and treatment of febrile neutropenia among solid tumor patients. It is considered an effective and relatively safe supportive care medication; however, it can cause rare and serious side effects such as spleen rupture or infarction.

Case Presentation: We are reporting a case of a 27-year-old female with breast cancer who has been treated with dose-dense chemotherapy and received colony-stimulating factor as primary prevention of febrile neutropenia that was complicated halfway through with splenic infarction. Read More

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http://dx.doi.org/10.1155/2019/8174986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393871PMC
February 2019
1 Read

Splenic Marginal Zone B-Cell Lymphoma With Splenic Infarction in a Patient With Cold Agglutinin Disease.

Clin Nucl Med 2019 May;44(5):e372-e374

Pathology, Shiga General Hospital, Moriyama, Japan.

We report a case of splenic marginal zone B-cell lymphoma discovered in a 73-year-old man with cold agglutinin disease. PET/CT revealed splenomegaly with focally intense uptake of F-FDG and diffusely increased bone marrow uptake, which was considered to be secondary to hemolytic anemia. Splenectomy was performed. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002528DOI Listing
May 2019
5 Reads

Sickle cell diseases: What can nuclear medicine offer?

Hell J Nucl Med 2019 Jan-Apr;22(1):2-3. Epub 2019 Mar 7.

Nuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Bari, Italy.

Sickle cell disease (SCD) is the best known haemoglobinopathy, caused by a mutation substituting valina for glutamic acid at position 6 of the beta-globin chain of adult hemoglobin A, resulting in hemoglobin S (HbS). The homozygous HbS disease (HbSS), an autosomal recessive disorder, is the most common form and the Mediterranean area, along with sub-Saharian African and India, have the highest prevalence (1%-15%). In particular, Sicily with a prevalence of 2%-5%, is among the most interested regions. Read More

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http://dx.doi.org/10.1967/s002449910950DOI Listing
March 2019
1 Read

[Essential thrombocythemia accompanied by adrenal infarction].

Rinsho Ketsueki 2019;60(2):106-111

Department of Hematology, Kyoto City Hospital.

A 64-year-old man presented to the emergency department with sudden-onset upper abdominal pain and pain in the left chest area. His platelet count was 121.7×10/µl. Read More

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http://dx.doi.org/10.11406/rinketsu.60.106DOI Listing
January 2019
7 Reads

PR3 vasculitis presenting with symptomatic splenic and renal infarction: a case report and literature review.

BMC Nephrol 2019 Mar 6;20(1):84. Epub 2019 Mar 6.

Department of Renal Medicine, Royal Berkshire Hospital, Royal Berkshire NHS Foundation Trust, Reading, UK.

Background: ANCA-associated vasculitis is a life-threatening, systemic autoimmune disease. There is an increased risk of organ infarction but in many cases this is asymptomatic. We described here the first reported case of PR3 vasculitis presenting with symptomatic bilateral renal wedge infarction. Read More

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http://dx.doi.org/10.1186/s12882-019-1266-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404344PMC
March 2019
5 Reads

Laparoscopic splenectomy for polysplenia with splenic torsion: a case report.

Surg Case Rep 2019 Feb 18;5(1):28. Epub 2019 Feb 18.

Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, Japan.

Background: Polysplenia refers to the presence of two or more equal-sized spleens. Very rarely, one of the multiple spleens may develop torsion and infarction.

Case Presentation: A 21-year-old woman presented with left upper quadrant pain, the cause of which could not be diagnosed. Read More

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http://dx.doi.org/10.1186/s40792-019-0582-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379504PMC
February 2019
1 Read

Obesogenic diet in aging mice disrupts gut microbe composition and alters neutrophil:lymphocyte ratio, leading to inflamed milieu in acute heart failure.

FASEB J 2019 Feb 15:fj201802477R. Epub 2019 Feb 15.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.

Calorie-dense obesogenic diet (OBD) is a prime risk factor for cardiovascular disease in aging. However, increasing age coupled with changes in the diet can affect the interaction of intestinal microbiota influencing the immune system, which can lead to chronic inflammation. How age and calorie-enriched OBD interact with microbial flora and impact leukocyte profiling is currently under investigated. Read More

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http://dx.doi.org/10.1096/fj.201802477RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463911PMC
February 2019
2 Reads

Treatment with mononuclear cell populations improves post-infarction cardiac function but does not reduce arrhythmia susceptibility.

PLoS One 2019 14;14(2):e0208301. Epub 2019 Feb 14.

Department of Cardiology, University of Bonn, Bonn, Germany.

Background: Clinical and experimental data give evidence that transplantation of stem and progenitor cells in myocardial infarction could be beneficial, although the underlying mechanism has remained elusive. Ventricular tachyarrhythmia is the most frequent and potentially lethal complication of myocardial infarction, but the impact of mono nuclear cells on the incidence of ventricular arrhythmia is still not clear.

Objective: We aimed to characterize the influence of splenic mononuclear cell populations on ventricular arrhythmia after myocardial infarction. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208301PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375577PMC
February 2019
4 Reads

An Unusual Case of Large-Vessel Vasculitis.

Eur J Case Rep Intern Med 2018 26;5(7):000897. Epub 2018 Jul 26.

Department of Medicine (Rheumatology), Hamad Medical Corporation, Doha, Qatar.

We report the case of a previously healthy 35-year-old man who presented with severe abdominal pain, nausea, vomiting and subjective fever and was found to have acute kidney injury, haematuria, leukocytosis and elevated inflammatory markers. An abdominal CT scan showed lobar nephronia of the left kidney complicated by infarction. Subsequent MRI also revealed splenic infarction. Read More

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http://dx.doi.org/10.12890/2018_000897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346781PMC
July 2018
2 Reads

Atraumatic Splenic Rupture after Myocardial Infarction.

Eur J Case Rep Intern Med 2018 24;5(4):000827. Epub 2018 Apr 24.

Doncaster Royal Infirmary, Doncaster, United Kingdom.

Atraumatic splenic rupture is a rare but potentially life-threatening event. It mostly happens when the spleen is already diseased; however, sometimes it can be drug induced in a previously normal spleen. Although anticoagulation has been attributed to spontaneous splenic rupture quite frequently, the role of dual antiplatelet therapy is underestimated. Read More

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http://dx.doi.org/10.12890/2018_000827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346757PMC
April 2018
1 Read

Splenic infarction induced by epstein-barr virus infection in a patient with sickle cell trait.

J Paediatr Child Health 2019 Feb;55(2):249-251

Department of Pediatrics, Van Eslander Cancer Centre, Grosse Pointe Woods, Michigan, United States.

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http://dx.doi.org/10.1111/jpc.14376DOI Listing
February 2019
3 Reads

Splenic Artery Aneurysms, A Rare Complication of Type 1 Gaucher Disease: Report of Five Cases.

J Clin Med 2019 Feb 8;8(2). Epub 2019 Feb 8.

Reference Centre of Lysosomal Diseases, University Hospital Beaujon, 100 Boulevard du Général Leclerc, 92110 Clichy, France.

Type 1 Gaucher disease is a rare genetic lysosomal disorder due to acid betaglucosidase deficiency. The main features are thrombocytopenia, anemia, hepatosplenomegaly and complex skeletal disease. Complications include pulmonary hypertension, cirrhosis and splenic infarction; comorbidities, such as autoimmune phenomena, B-cell malignancies and Parkinson disease also occur. Read More

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http://dx.doi.org/10.3390/jcm8020219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406779PMC
February 2019
12 Reads

Splenic infarction as a rare presentation of severe babesiosis.

IDCases 2019 23;15:e00491. Epub 2019 Jan 23.

Department of Medicine, St. Vincent's Medical Center, Bridgeport, CT; The Frank H. Netter MD School of Medicine at Quinnipiac University, North Haven, CT, United States.

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http://dx.doi.org/10.1016/j.idcr.2019.e00491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355617PMC
January 2019

Cone beam versus conventional computed tomography angiography volume measurement in partial splenic embolization.

Medicine (Baltimore) 2019 Feb;98(5):e14312

When performing partial splenic arterial embolization (PSE), it can be difficult to determine the embolization ratio based on 2-dimensional digital subtraction angiography (DSA) image diagnosis alone. Therefore, at our department, we conduct computed tomography (CT) imaging intraoperatively and postoperatively to determine whether the planned embolization has been achieved. In recent years, developments in interventional radiology devices have enabled diagnostic imaging using cone beam CT. Read More

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http://dx.doi.org/10.1097/MD.0000000000014312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380856PMC
February 2019
1 Read

C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function.

Circulation 2019 Apr;139(15):1798-1812

Division of Molecular and Translational Cardiology, Department of Cardiology and Angiology (Y.W., M.K.-K., H.F., E.B., A.K., K.C.W.), Hannover Medical School, Germany.

Background: Acute myocardial infarction (MI) elicits an inflammatory response that drives tissue repair and adverse cardiac remodeling. Inflammatory cell trafficking after MI is controlled by C-X-C motif chemokine ligand 12 (CXCL12) and its receptor, C-X-C motif chemokine receptor 4 (CXCR4). CXCR4 antagonists mobilize inflammatory cells and promote infarct repair, but the cellular mechanisms are unclear. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036053DOI Listing
April 2019
2 Reads
14.430 Impact Factor

Pulmonary embolism with migrating thrombus through patent foramen ovale: A case for a mixed pharmacological and percutaneous management.

J Cardiol Cases 2019 Jan 27;19(1):19-21. Epub 2018 Sep 27.

Interventional Cardiology Unit, S. Ambrogio Cardio-Thoracic Center, Milan, Italy.

A 61-year-old man, admitted to our hospital for bilateral pulmonary embolism, complicated by right renal ischemia and multiple splenic infarcts due to a mobile thrombus entrapped in a patent foramen ovale, has been successfully treated with apixaban 5 mg twice daily followed by transcatheter patent foramen ovale closure. < Apixaban could be a therapeutic alternative to thrombolysis and surgery in patients with warfarin-resistant thrombus straddling in the patent foramen ovale (PFO). Furthermore, apixaban could be a simple and useful option to manage patients undergoing transcatheter PFO closure. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342615PMC
January 2019
2 Reads

Association between MTHFR 677C>T polymorphism and vascular complications in sickle cell disease: A meta-analysis.

Transfus Clin Biol 2019 Jan 10. Epub 2019 Jan 10.

Sickle Cell Institute Chhattisgarh, Forest Block-2, Jail Road, Raipur 492001, Chhattisgarh India. Electronic address:

Sickle cell disease (SCD) is considered as a vascular disease due to its chronic vascular manifestations such as leg ulcers, priapism, acute chest syndrome (ACS), stroke, retinopathy, renal insufficiency, pulmonary hypertension, avascular necrosis of the femoral head (AVNF) and splenic infarction. Emerging evidence has shown that the MTHFR 677C>T variant allele is associated with vascular complications (VC) in patients with SCD; however, results from individual studies are inconclusive. The aim of this meta-analysis is to evaluate the association between the MTHFR 677C>T polymorphism and the susceptibility for VC in SCD patients. Read More

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http://dx.doi.org/10.1016/j.tracli.2019.01.003DOI Listing
January 2019
2 Reads

"Bright Band Sign" A Grayscale Ultrasound Finding in Hepatic Infarction.

J Ultrasound Med 2019 Jan 21. Epub 2019 Jan 21.

Department of Radiology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

Hepatic infarction is infrequent due to the dual blood supply of the liver and the compensatory relationship between the hepatic artery and portal vein. Most cases occur in liver transplants due to vascular complications. Grayscale sonography combined with color and spectral wave Doppler can assess for vessel patency and parenchymal abnormalities. Read More

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http://dx.doi.org/10.1002/jum.14939DOI Listing
January 2019

Serum Troponin Level in Acute Ischemic Stroke Identifies Patients with Visceral Infarcts.

J Stroke Cerebrovasc Dis 2019 May 18;28(5):1173-1177. Epub 2019 Jan 18.

Department of Neurology, the Warren Alpert Medical School of Brown University, Providence, Rhode Island. Electronic address:

Background And Purpose: Patients with ischemic stroke of cardioembolic origin are at risk of visceral (renal or splenic) infarction. We hypothesized that serum troponin level at time of ischemic stroke would be associated with presence of visceral infarction.

Methods: Data were abstracted from a single center prospective stroke database over 18 months and included all patients with ischemic stroke who underwent contrast-enhanced computerized tomography (CT) of the abdomen and pelvis for clinical purposes within 1 year of stroke. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10523057193000
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.01.004DOI Listing
May 2019
11 Reads

Non-traumatic splenic rupture secondary to haemorrhagic infarct in diffuse large B-cell lymphoma.

BMJ Case Rep 2019 Jan 17;12(1). Epub 2019 Jan 17.

Department of Radiology, Queen Mary Hospital, Hong Kong, Hong Kong.

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http://dx.doi.org/10.1136/bcr-2018-229052DOI Listing
January 2019
4 Reads

Splenic Infarction in Acute Cytomegalovirus and Human Parvovirus Concomitant Infection.

Case Rep Infect Dis 2018 3;2018:7027656. Epub 2018 Dec 3.

Division of Medical Oncology and Molecular Respirology, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, Tottori, Japan.

We present a case report of a 35-year-old woman who had splenic infarction. She had persistent high fever, systemic joint pain, and abnormal liver function. She was diagnosed with cytomegalovirus and human parvovirus B19 concomitant infection. Read More

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http://dx.doi.org/10.1155/2018/7027656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304844PMC
December 2018
2 Reads

Two Imported Cases of Babesiosis with Complication or Co-Infection with Lyme Disease in Republic of Korea.

Korean J Parasitol 2018 Dec 31;56(6):609-613. Epub 2018 Dec 31.

Department of Internal Medicine, Inha University School of Medicine, Incheon 22212, Korea.

Babesiosis, caused by Babesia microti and B. divergens, is transmitted by Ixodid ticks. Symptoms of babesiosis vary from a mild flu-like illness to acute, severe, and sometimes fatal and fulminant disease. Read More

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2018.56
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http://dx.doi.org/10.3347/kjp.2018.56.6.609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327201PMC
December 2018
6 Reads

Splenic Infarction as Only Manifestation of Antiphospholipid Syndrome in a Patient With Rheumatoid Arthritis.

J Clin Rheumatol 2018 Dec 28. Epub 2018 Dec 28.

From the Department of Emergency and Organ Transpantations, Rheumatology Unit, University of Bari, Bari, Italy.

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http://dx.doi.org/10.1097/RHU.0000000000000964DOI Listing
December 2018
2 Reads

You're the Flight Surgeon.

Authors:

Aerosp Med Hum Perform 2019 Jan;90(1):63-64

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http://dx.doi.org/10.3357/AMHP.5210.2019DOI Listing
January 2019

Vanishing spleen syndrome post right partial nephrectomy in a sicklemic patient.

Pan Afr Med J 2018 16;30:211. Epub 2018 Jul 16.

Division of Urology, Harlem Hospital Center, Columbia University, New York, NY, USA.

Splenic infarction after contralateral laparoscopic renal surgery has not, to our knowledge, been reported. The spleen is the most affected organ in sickle cell disease and the mechanism of auto infarction is thought to result from the crystallization of abnormal hemoglobin during periods of hypoxia or acidosis resulting in parenchymal ischemia and ultimately tissue necrosis. We report a case of 45 year old female with sickle cell disease who had an unremarkable spleen at the time of a laparoscopic right partial nephrectomy and was subsequently found to have marked diminution in her splenic volume. Read More

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http://www.panafrican-med-journal.com/content/article/30/211
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http://dx.doi.org/10.11604/pamj.2018.30.211.15454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294983PMC
January 2019
11 Reads

Mowat-Wilson Syndrome Presenting With Purpura Fulminans.

Pediatrics 2019 Jan;143(1)

Division of Pediatric Hospital Medicine, Advocate Children's Hospital, Park Ridge, Illinois.

Purpura fulminans is a rapidly progressive syndrome of intravascular thrombosis and hemorrhagic infarction of the skin. The most common infectious etiology is sepsis, and less commonly it has been documented as a complication of invasive In children who are otherwise healthy, splenic dysfunction is a significant predisposing factor for invasive pneumococcal infection. We present the case of a 10-month-old girl with a history of developmental delay, who developed an overwhelming infection complicated by purpura fulminans and was found to have previously undiagnosed Mowat-Wilson syndrome with anatomic asplenia. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-0922DOI Listing
January 2019
13 Reads

Canis Caveat (Beware of the Dog) - Septic Shock Due To Capnocytophaga Canimorsus Contracted From A Dog Bite

Ir Med J 2018 Dec 6;111(10):842. Epub 2018 Dec 6.

Department of Intensive Care Medicine, St. Vincent’s University Hospital

We describe the case of a 61-year-old immunocompetent male who developed septic shock and multiorgan failure due to Capnocytophaga canimorsus (C. canimorsus) bloodstream infection, sustained from a dog bite. Unusually, this patient developed acute liver failure and splenic infarction in addition to many of the better-known clinical sequelae of C. Read More

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December 2018

Renal and Splenic Infarction in a Patient with Familial Hypercholesterolemia and Previous Cerebral Infarction.

Am J Case Rep 2018 12 10;19:1463-1466. Epub 2018 Dec 10.

Department of Internal Medicine, Haga Teaching Hospital, Hague, Netherlands.

BACKGROUND This is a case report of a male patient who presented with a history of right flank pain based on renal infarction. Initially the symptoms were misdiagnosed as acute pyelonephritis. CASE REPORT A 47-year-old male with a history of familial hypercholesterolemia and cerebral infarction presented at the Emergency Department with a 3-day history of acute right-sided flank pain. Read More

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https://www.amjcaserep.com/abstract/index/idArt/911990
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http://dx.doi.org/10.12659/AJCR.911990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298247PMC
December 2018
11 Reads

Splenic infarction due to cytomegalovirus infection in an immunocompetent patient.

Med Clin (Barc) 2018 Nov 27. Epub 2018 Nov 27.

Servicio de Medicina Interna, Hospital Garcia Orcoyen, Estella, Navarra, España.

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http://dx.doi.org/10.1016/j.medcli.2018.10.015DOI Listing
November 2018
11 Reads

Massive Splenic Infarction in a Child With Sickle Cell Disease on Chronic Transfusion Therapy.

J Pediatr Hematol Oncol 2019 Mar;41(2):e79-e82

Departments of Pediatrics.

Massive splenic infarction (MSI) is a rare complication of sickle cell disease, as the spleen generally atrophies within the first few years of life. We report a case of MSI in a 12-year-old boy with homozygous sickle cell anemia (Hb SS) whose chronic transfusion therapy resulted in hypersplenism. The occurrence of a complicated MSI in our patient should perhaps further encourage elective splenectomy in such patients, despite known potential perioperative complications and postsplenectomy risks of infection and thrombosis. Read More

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http://dx.doi.org/10.1097/MPH.0000000000001356DOI Listing
March 2019
16 Reads

Infarct-Sparing Effect of Adenosine A2B Receptor Agonist Is Primarily Due to Its Action on Splenic Leukocytes Via a PI3K/Akt/IL-10 Pathway.

J Surg Res 2018 12 23;232:442-449. Epub 2018 Jul 23.

Department of Surgery, University of Virginia Health System, Charlottesville, Virginia. Electronic address:

Background: Adenosine A2B receptor (AAR) agonist reduces myocardial reperfusion injury by acting on inflammatory cells. Recently, a cardiosplenic axis was shown to mediate the myocardial postischemic reperfusion injury. This study aimed to explore whether the infarct-squaring effect of AAR agonist was primarily due to its action on splenic leukocytes. Read More

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http://dx.doi.org/10.1016/j.jss.2018.06.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251504PMC
December 2018
14 Reads

[Splenic infarction revealing infectious endocarditis in a pregnant woman: about a case and brief literature review].

Pan Afr Med J 2018 27;30:184. Epub 2018 Jun 27.

Service de Gynécologie-Obstétrique, Hôpital Militaire d'Instruction, Rabat, Maroc.

The diagnosis of splenic infarction is rarely reported in pregnant women. Current incidence of splenic infarction, especially during infectious endocardites as well as diagnostic methods used are poorly specified in the literature. We here report the case of a 26-year old woman with no particular previous history or cardiovascular risk factor who, at the end 14 weeks of amenorrhea, presented to the Emergency Department with febrile syndrome evolving over 10 days and abdominal pain of recent onset at the level of the left hypochondre. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.184.14262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235498PMC
December 2018
14 Reads

Ultrasonography of the pediatric spleen: a pictorial essay.

J Ultrasound 2018 Nov 16. Epub 2018 Nov 16.

Paediatric Radiology Department, "Federico II" University Hospital, Naples, Italy.

In infants and children, the spleen is involved in many pathological processes, whether those processes are isolated or related to systemic diseases. Pathology of the pediatric spleen includes congenital anomalies, splenomegaly, trauma, focal lesions, infarction, and tumors. Ultrasonography (US) is a widely available, fast, noninvasive imaging technique to assess the size, shape, and position of the spleen, as well as to define splenic echotexture. Read More

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http://link.springer.com/10.1007/s40477-018-0341-2
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http://dx.doi.org/10.1007/s40477-018-0341-2DOI Listing
November 2018
20 Reads

Splenic embolization for a giant splenic hemangioma in a child: a case report.

BMC Pediatr 2018 Nov 12;18(1):354. Epub 2018 Nov 12.

Department of Pediatrics, Chungbuk National University Hospital, Cheongju, Republic of Korea.

Background: Splenic hemangioma is the most common benign tumor of the spleen. However, it remains a rare medical condition in children. Although the natural course of splenic hemangioma is slow growth, treatment for large splenic hemangiomas has been recommended due to the risk of spontaneous rupture causing life-threating hemorrhage. Read More

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http://dx.doi.org/10.1186/s12887-018-1331-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233546PMC
November 2018
18 Reads

Laparoscopic splenic pseudocyst management using indocyanine green dye: An adjunct tool for better surgical outcome.

J Minim Access Surg 2018 Nov 9. Epub 2018 Nov 9.

Department of General and Minimal Access Surgery and Robotic Surgery, Indraprastha Apollo Hospitals, New Delhi, India.

Splenic cysts are not so common in incidence. Only 800-850 cases have been reported till now in the literature. Splenic cysts can be further classified into parasitic and non-parasitic cysts. Read More

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http://dx.doi.org/10.4103/jmas.JMAS_156_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438074PMC
November 2018
3 Reads

Thrombus on the inflow cannula of the HeartWare HVAD: an update.

Cardiovasc Pathol 2019 Jan - Feb;38:14-20. Epub 2018 Sep 15.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115. Electronic address:

Background: The HeartWare HVAD (Medtronic, Minneapolis, MN) is a continuous-flow left ventricular assist device (LVAD) approved by the FDA in 2012 as a bridge to transplant in patients with end-stage left ventricular heart failure. The current inflow cannula has a smooth outer surface near the inflow edge and a sintered collar of titanium microspheres near the pump. A previous case series of HVAD patients bridged to transplant revealed thrombus on the outer surface of the inflow cannula in 8 of 8 patients, predominantly at the smooth-sintered interface, that was associated with a clinical stroke rate of 12. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10548807183015
Publisher Site
http://dx.doi.org/10.1016/j.carpath.2018.09.002DOI Listing
March 2019
26 Reads

Simultaneous occurrence of five prothrombotic induced vaso-occlusive phenomena and focal nodular hyperplasia due to prolonged use of combined oral contraceptive pills.

BJR Case Rep 2018 15;4(2):20170070. Epub 2017 Dec 15.

M.P Shah Hospital, University of Nairobi, Nairobi, Kenya.

This is a rare case of a patient simultaneously presenting with five complications associated with the prolonged (5 years) use of combined oral contraceptives. The two main ingredients of combined oral contraceptives responsible for thromboembolism are estrogen (estradiol) and progestogen (progestin). Progestins are linked with occlusion of arteries while estrogens can induce both arterial and venous thrombosis. Read More

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http://dx.doi.org/10.1259/bjrcr.20170070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159115PMC
December 2017
3 Reads

Contrast-enhanced ultrasound in the evaluation of splenic injury healing time and grade.

Radiol Med 2019 Mar 25;124(3):163-169. Epub 2018 Oct 25.

SOD Radiologia Pediatrica e Specialistica, Azienda Ospedaliero Universitaria Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy.

Aims: To assess mean healing time of blunt spleen injuries managed nonoperatively using CEUS (contrast-enhanced ultrasound); to analyze whether spleen injury grade, subcapsular hematoma (SCH) presence, SCH grade and spleen infarct after spleen artery angioembolization could be related to healing time; and to evaluate CEUS sensitivity in diagnosing spleen injury and to assess CEUS performance in classifying spleen injury grade compared to CT.

Materials And Methods: After CT evaluation in the Emergency Department, 101 hemodynamic stable blunt spleen trauma patients (73 males; 28 females; mean age 46.4 years, range 18-92) underwent serial CEUS follow-up examinations at pre-established intervals (1, 3, 8, 15, 30, 60, 90 and 180 days after trauma), until spleen injury became no more identifiable. Read More

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http://dx.doi.org/10.1007/s11547-018-0954-8DOI Listing
March 2019
16 Reads

Vago-Splenic Axis in Signal Transduction of Remote Ischemic Preconditioning in Pigs and Rats.

Circ Res 2018 Oct;123(10):1152-1163

From the Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Germany (H.R.L., P.K., A.S., H.H., G.H.).

Rationale: The signal transduction of remote ischemic conditioning is still largely unknown.

Objective: Characterization of neurohumoral signal transfer and vago-splenic axis in remote ischemic preconditioning (RIPC).

Methods And Results: Anesthetized pigs were subjected to 60 minutes of coronary occlusion and 180 minutes of reperfusion (placebo+ischemia/reperfusion [PLA+I/R]). Read More

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31385
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.118.313859DOI Listing
October 2018
14 Reads

[Management of Visceral Artery Aneurysms with Preservation of Organ Perfusion: More Than Twenty Years Experience].

Zentralbl Chir 2018 Oct 24;143(5):516-525. Epub 2018 Oct 24.

Abteilung für Gefäßchirurgie, Universitätsklinikum Regensburg, Deutschland.

Background: Visceral artery aneurysms (VAA) are rare and often incidental findings. Indications for treatment are symptomatic patients, pseudoaneurysms and a true aneurysm of diameter of ≥ 2.5 cm for mesenteric arteries and ≥ 3 cm for renal artery aneurysms. Read More

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http://dx.doi.org/10.1055/a-0750-6016DOI Listing
October 2018
4 Reads

Left lower quadrant pain: an unlikely diagnosis in a case of acute abdomen.

J Community Hosp Intern Med Perspect 2018 15;8(5):296-299. Epub 2018 Oct 15.

Department of Medicine, Easton Hospital, Easton, PA, USA.

Splenic infarct is an incredibly rare diagnosis for abdominal pain. One study involving two hospitals over ten years describes only 0.0037% of all hospital admissions presenting with splenic infarction. Read More

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https://www.tandfonline.com/doi/full/10.1080/20009666.2018.1
Publisher Site
http://dx.doi.org/10.1080/20009666.2018.1517578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197027PMC
October 2018
14 Reads

Spontaneous Celiac Artery Dissection Presenting With Splenic Infarction: A Case Report.

Gastroenterology Res 2018 Oct 1;11(5):379-382. Epub 2018 Oct 1.

Department of Internal Medicine, Advocate Illinois Masonic Medical Center, 836 W Wellington Ave., Chicago, IL 60657, USA.

Spontaneous isolated celiac artery dissection (SICAD) is extremely rare. We herein report a case of a 43-year-old male with no known history of cardiovascular disease who presented to the emergency department (ED) with sudden onset severe epigastric abdominal pain without a known trigger. Abdominal computed tomography (CT) scan showed a focal dissection and irregular enhancement of the celiac trunk with associated splenic artery embolus and large splenic infarct. Read More

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http://dx.doi.org/10.14740/gr1065wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188032PMC
October 2018
1 Read

Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion.

J Neuroinflammation 2018 Oct 15;15(1):288. Epub 2018 Oct 15.

Department of Neurology, University of Kentucky, 741 S. Limestone BBSRB B457, Lexington, KY, 40536-0905, USA.

Background: The migration of peripheral immune cells and splenocytes to the ischemic brain is one of the major causes of delayed neuroinflammation after permanent large vessel stroke. Other groups have demonstrated that leukemia inhibitory factor (LIF), a cytokine that promotes neural cell survival through upregulation of antioxidant enzymes, promotes an anti-inflammatory phenotype in several types of immune cells. The goal of this study was to determine whether LIF treatment modulates the peripheral immune response after stroke. Read More

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https://jneuroinflammation.biomedcentral.com/articles/10.118
Publisher Site
http://dx.doi.org/10.1186/s12974-018-1326-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190542PMC
October 2018
22 Reads

POEMS syndrome complicated with multiple ischemic vascular events: case report and review of literature.

Onco Targets Ther 2018 27;11:6271-6276. Epub 2018 Sep 27.

Department of Hematology, University Emergency Hospital Bucharest, Bucharest, Romania,

POEMS syndrome (acronym consisting of: polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) is an uncommon disorder associated with an underlying plasma cell dyscrasia. There is no single specific test for POEMS, and due to its rarity and heterogeneity, patients are often mis- or underdiagnosed. Castleman disease (CD) is a rare lymphoproliferative disorder, closely related to POEMS syndrome; ~11%-30% of POEMS patients are associated with concomitant CD. Read More

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https://www.dovepress.com/poems-syndrome-complicated-with-mu
Publisher Site
http://dx.doi.org/10.2147/OTT.S146221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166759PMC
September 2018
8 Reads

Spontaneous splenic rupture secondary to dabigatran: the last in a series of unfortunate events.

Clin Med (Lond) 2018 Oct;18(5):406-408

Royal Berkshire Hospital, Reading, UK.

We present the case of a 77-year-old woman who had an accidental fall in her garden, resulting in a fracture of her left ankle. After manipulation of the fracture, she developed sudden onset shortness of breath. An echo led to the diagnosis of Takotsubo cardiomyopathy. Read More

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http://www.clinmed.rcpjournal.org/lookup/doi/10.7861/clinmed
Publisher Site
http://dx.doi.org/10.7861/clinmedicine.18-5-406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334098PMC
October 2018
5 Reads