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Open Med (Wars) 2022 25;17(1):808-815. Epub 2022 Apr 25.

Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, Zhenjiang 212003, Jiangsu Province, China.

Splenic embolization is a minimally invasive alternative to splenectomy for the treatment of hypersplenism. This was a retrospective study of 101 patients with hypersplenism caused by cirrhosis who were treated with splenic embolization and for whom 6 months of follow-up data were available. Of these patients, 65 underwent partial splenic artery embolization (PSE), including 23 who underwent repeated PSE (RPSE). Read More

J Surg Res 2022 Apr 20;277:44-49. Epub 2022 Apr 20.

Department of Surgery, Wright State University, Dayton, Ohio.

Introduction: Splenic artery embolization (SAE) is a routinely used adjunct in the nonoperative management (NOM) of blunt splenic injury (BSI). The purpose of this study was to evaluate the rate and type of adverse events that occur in patients undergoing SAE and to compare this with the previous data.

Methods: Patients who had SAE for BSI between 2011 and 2018 were identified. Read More

Vet Clin Pathol 2022 Apr 15. Epub 2022 Apr 15.

Colorado State University, Fort Collins, Colorado, USA.

An 11-year-old spayed female Basset Hound was presented to the Colorado State University Veterinary Teaching Hospital for evaluation of a 7-week history of intermittent collapse, waxing and waning lethargy, and hyporexia. Abdominal ultrasound revealed a 6-mm hypoechoic splenic nodule that, on cytologic evaluation, revealed marked neutrophilic inflammation with intracellular and extracellular bacterial rods frequently producing oval subterminal to terminal endospores, suggestive of Clostridium. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) performed on bacteria isolated from this nodule initially identified a Clostridium species, which was eventually confirmed with 16 s rDNA sequencing. Read More

Future Cardiol 2022 May 11;18(5):385-391. Epub 2022 Apr 11.

Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL, UK.

Complete heart block, aortic root abscess and aortic valve regurgitation are well-recognized complications of infective endocarditis of the aortic valve. Splenic abscess and aorto-cavitary fistula are rarer phenomena and are indicative of calamitous infection. The authors present the case of an otherwise healthy 61-year-old man presenting with a 2-month history of non-specific symptoms, who developed suppurative endocarditis with a fistulating aortic root abscess, combined with severe sepsis, splenic embolization and complete heart block. Read More

Cureus 2022 Mar 7;14(3):e22936. Epub 2022 Mar 7.

Department of Internal Medicine and Pediatrics, Rutgers University New Jersey Medical School, Newark, USA.

is an opportunistic organism that can commonly cause respiratory tract infections in immunocompromised individuals. It has also been shown to cause urinary tract infections and soft tissue infections. It has several virulence factors including fimbriae-like adhesions that allow for surface attachment and biofilm formation to increase the likelihood of infections in humans. Read More

Medicine (Baltimore) 2022 Feb;101(7):e28656

Center of Infectious Disease, West China Hospital, Sichuan University, 37 Guoxue Lane, Chengdu, China.

Rationale: The clinical manifestations in patients with disseminated tuberculosis (TB) are nonspecific and may present challenges for early diagnosis.

Patient Concerns And Diagnoses: We describe the case of a 44-year-old man who presented with abdominal pain and discomfort for more than a month. He had undergone surgery for a chest wall abscess 9 months ago. Read More

Arch Argent Pediatr 2022 Apr 4;120(2):e93-e97. Epub 2022 Feb 4.

Servicio de Oftalmología, Hospital Infantil Universitario Niño Jesús de Madrid, España.

Infectious myositis, whether viral or bacterial, is frequent in pediatric age. It causes muscle pain and weakness, associated with fever and general malaise. One cause is Bartonella henselae, responsible for cat scratch disease, which sometimes causes systemic symptoms. Read More

Qatar Med J 2022 12;2022(1):16. Epub 2022 Mar 12.

Department of Medicine, Hamad General Hospital, Doha, Qatar E-mail:

Background & Objectives: Splenic abscess (SA) is a rare clinical entity. There is a lack of information on SA in most Arab and Gulf countries, including Qatar. This study describes the demographics, clinical features, microbiologic etiologies, treatments, and outcomes of patients with SA at the largest tertiary medical center in Qatar over the previous six years. Read More

Radiographics 2022 May-Jun;42(3):683-701. Epub 2022 Mar 18.

From the Department of Radiology, MedStar Georgetown University Hospital, 3800 Reservoir Rd NW, CCC Building Ground Floor, CG 201, Washington, DC 20007 (N.K., M.A.M.); the Joint Pathology Center, Silver Spring, Md (A.A.); and the American Institute for Radiologic Pathology, Silver Spring, Md (M.A.M.).

Splenic lesions are commonly discovered incidentally at imaging, without clinical signs or symptoms that may aid in diagnosis. As such, the differential diagnosis and subsequent management are based primarily on imaging characteristics. Much has been written about the myriad pathologic conditions that can occur in the spleen; however, there is little guidance on the approach to an incidental splenic mass. Read More

Open Forum Infect Dis 2022 Apr 17;9(4):ofac085. Epub 2022 Feb 17.

Yale University School of Medicine, New Haven, Connecticut, USA.

Background: Splenic abscess is a rare infection often resulting from hematogenous spread. Immunocompromised states are commonly comorbid, and the microbiology is heterogeneous.

Methods: We conducted a retrospective review of 33 cases identified by convenience sampling. Read More

Indian Dermatol Online J 2022 Mar-Apr;13(2):244-247. Epub 2022 Mar 3.

Department of Dermatology, Venereology and Leprology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

Pyoderma gangrenosum is a rare, chronic neutrophilic dermatosis of unknown etiology. The classical clinical feature of pyoderma gangrenosum is a pustule or plaque that rapidly progresses to a painful, necrotic ulcer with undermined violaceous margins. Pyoderma gangrenosum may be associated with underlying inflammatory bowel diseases, hematological malignancies, or rheumatologic disorders in 50-70% of the cases. Read More

Mod Rheumatol Case Rep 2022 Mar 11. Epub 2022 Mar 11.

Department of Pediatrics, Graduate School of Medicine, Chiba University, Japan.

Behçet's disease (BD) is often associated with neutrophilic dermatosis. However, BD is rarely associated with aseptic abscesses in the spleen or liver. A 2-year-old girl presented to our hospital with a two-week history of fever, abdominal pain, and a skin ulcer on her leg. Read More

Transplant Proc 2022 Mar 7. Epub 2022 Mar 7.

Department of Surgery, Westmead Hospital, Sydney, Australia; Department of transplantation, Royal Prince Alfred Hospital, Sydney, Australia; University of Sydney, Specialty of Surgery, Sydney, Australia. Electronic address:

Background: Splenic artery aneurysms (SAA), although rare in the general population, occur more commonly in liver transplant candidates owing to cirrhosis-induced portal hypertension. In this population, particularly in the perioperative period, SAAs are at heightened risks of rupture with potentially fatal consequences. There is no consensus regarding optimal management of asymptomatic SAA diagnosed before liver transplantation. Read More

J Paediatr Child Health 2022 Mar 8. Epub 2022 Mar 8.

Department of Radiology, Faculty of Medicine, Çukurova University, Adana, Turkey.

Aim: Echinococcosis with multi-organ/disseminated involvement is rare in childhood. We aimed to evaluate the clinical and laboratory characteristics and prognosis in paediatric patients with echinococcosis having multiorgan/disseminated involvement.

Method: We evaluated retrospectively children with echinococcosis with involvement of three or more organs. Read More

J Infect Chemother 2022 Jul 4;28(7):965-970. Epub 2022 Mar 4.

Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan; Department of Infectious Disease, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai, 983-8356, Japan.

Tuberculosis remains a major public health concern. Millions of tuberculosis cases and associated deaths have been reported worldwide. The Indo-Oceanic lineage Mycobacterium tuberculosis is common in Southeast Asia and causes extrapulmonary lesions. Read More

Clin Case Rep 2022 Feb 23;10(2):e05493. Epub 2022 Feb 23.

Department of Medicine Regional Hospital Limbe Limbe Cameroon.

Although the spleen is frequently enlarged in association with systemic infection, splenic abscesses are rare. They result from direct or hematogenous spread, or when a hematoma becomes infected. We present a case of the rare splenic abscess in a low-resource setting. Read More

Braz J Infect Dis 2022 Mar-Apr;26(2):102336. Epub 2022 Feb 25.

Department of Nephrology, Rouen University Hospital, Bois-Guillaume, France.

We report a rare case of Campylobacter fetus bacteremia in a 50-year-old woman following kidney transplantation. Bacteremia was complicated by multivisceral signs such as multiple splenic abscesses, bacterial hepatitis, erythema nodosum and reactive arthritis. Despite a prolonged diagnostic delay, the diagnosis was made on blood culture identification and the global outcome was favorable with adequate antibiotherapy. Read More

Int J Surg Case Rep 2022 Mar 12;92:106828. Epub 2022 Feb 12.

General Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Introduction And Importance: Enteric fistulas commonly arise from inflammatory, infectious, or neoplastic processes. Colosplenic fistulas are rare with only several reported worldwide.

Case Presentation: Herein, we present a case of colosplenic fistula in a 39-year-old gentleman with past history of rectal cancer previously in remission. Read More

J Int Med Res 2022 Feb;50(2):3000605221080875

University of Samsun, Samsun Training and Research Hospital, Department of General Surgery, Samsun, Turkey.

Objective: Although rare, late-diagnosed atraumatic splenic rupture (ASR) may result in mortality. We investigated the occurrence of ASR cases at our centre over the previous six years.

Methods: This was a retrospective, cross-sectional study that included all patients who underwent emergency splenectomy due to ASR between January 01, 2015, and January 01, 2021. Read More

IDCases 2022 25;27:e01413. Epub 2022 Jan 25.

Tokyo Bay Urayasu Ichikawa Iryo Center, Tokyo, Japan.

Splenic abscesses are rare, but can be life-threatening. Antibiotics, percutaneous drainage and splenectomy are the usual treatment options. However, there is no ideal algorithm for choosing among these options. Read More

Cureus 2022 Jan 18;14(1):e21396. Epub 2022 Jan 18.

Community Medicine Management, Shimane University Faculty of Medicine, Izumo, JPN.

Infective endocarditis (IE) is caused by vegetations, consisting of platelets, fibrin, inflammatory cells, and microcolonies of bacteria, fungi, rickettsia, chlamydia, and viruses, that form in the heart valves, endocardium, and large vessel intima.  endocarditis is highly tissue destructive, usually follows an acute course, and tends to become severe due to valve destruction, surrounding abscesses, and distant seeding. The main complications of IE due to  are heart failure due to destruction of tendon cords and valves, perivalvular abscesses and fistulas, and the dissemination of septic emboli to various organs including the brain, kidney, spleen, and lungs. Read More

J Pak Med Assoc 2022 Jan;72(1):168-170

Department of Surgery, Mayo Hospital, Lahore, Pakistan.

Ruptured splenic abscess has been reported as a rare clinical entity in literature. We present the case of a middle aged female with peritonitis due to a ruptured splenic abscess. Emergency splenectomy was done and broad spectrum antibiotic was given postoperatively. Read More

Case Rep Surg 2022 15;2022:9279418. Epub 2022 Jan 15.

Department of Surgery, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.

Splenic abscess is a rare clinical entity with diagnostic challenges. Though rare, it is potentially a life-threatening clinical condition with high mortality reaching more than 70%. The common signs and symptoms include the triad of fever, left upper quadrant tenderness, and leukocytosis. Read More

Medicine (Baltimore) 2022 Jan;101(1):e28522

Lucian Blaga University of Sibiu, Faculty of Medicine, Sibiu, Romania.

Rationale: Infections with Sphingomonas paucimobilis are rarely described in the literature and can be community-acquired or associated with healthcare, especially in patients with chronic conditions (e.g., diabetes mellitus), malignancies, or other causes of immunosuppression, except in people without comorbidities. Read More

Zhongguo Zhen Jiu 2022 Jan;42(1):66-72

Beijing Hospital of TCM, Capital Medical University, Beijing Institute of TCM, Beijing Key Laboratory of Clinical Basic Research on Psoriasis, Beijing 100010, China.

Objective: To observe the effect of moxibustion on skin lesions and immune inflammatory response in psoriasis mice, and to explore the possible mechanism of moxibustion for psoriasis.

Methods: A total of 32 male BALB/c mice were randomly divided into a normal group, a model group, a moxibustion group and a medication group, 8 mice in each group. Psoriasis model was induced by applying 5% imiquimod cream on the back for 7 days in the model group, the moxibustion group and the medication group. Read More

Ugeskr Laeger 2022 01;184(1)

Yersinia pseudotuberculosis is a Gram-negative bacterium causing infection in humans through contaminated water and/or food. The infection commonly occurs as gastroenteritis and fever, abdominal pain due to mesenteric lymphadenitis and diarrhoea. Bacteraemia is rare and is typically seen in immunocompromised patients and occurs with different clinical presentations like Far East scarlet-like fever, splenic abscess, or mimic appendicitis. Read More

Lancet Microbe 2021 Dec;2(12):e695-e703

Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.

Background: Hypervirulent (hv) strains of capsule type K1 and K2 cause invasive infections associated with hepatic abscesses, which can be difficult to treat and are frequently associated with relapsing infections. Other strains (non-hv), including lineages that have acquired carbapenem resistance, do not manifest this pathology. In this work we aimed to test the hypothesis that within-macrophage replication is a key mechanism underpinning abscess formation in hv infections. Read More

IDCases 2022 6;27:e01357. Epub 2021 Dec 6.

Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.

A 58-year-old woman with COVID-19 presented with an acute abdomen. Her spleen was found to be infarcted with a large fluid and gas collection. Treatment included broad-spectrum antibiotics and CT-guided drainage. Read More

Surgery 2022 05 29;171(5):1417-1421. Epub 2021 Nov 29.

Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery, UC San Diego School of Medicine, CA. Electronic address:

Background: Hemorrhage due to delayed splenic rupture is a potentially fatal complication of nonoperative management of splenic injuries. Suboptimal postdischarge follow-up has made measuring the incidence of failed splenic salvage challenging. We hypothesized that readmission after splenic salvage is rare; however, readmissions for splenic conditions would be associated with a high rate of splenectomy. Read More

Trop Doct 2022 Jan 29;52(1):151-152. Epub 2021 Nov 29.

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 64076Suleyman Demirel University, School of Medicine, Isparta, Turkey.

COVID-19 can manifest with signs and symptoms related to many different systems. Therefore, in the examination of almost every patient, COVID-19 infection is excluded first This may cause other diseases to be missed, as almost occurred in the case of a 15-year old boy with brucellosis and a splenic abscess. Public and health care personnel fear of COVID-19 may cause more harm than the virus itself. Read More