925 results match your criteria Spiradenoma

A row of nodules on the right side of the face.

JAAD Case Rep 2022 Mar 21;21:126-129. Epub 2022 Jan 21.

Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.

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Letter from the Editor: What's in a name?

Dirk M Elston

J Am Acad Dermatol 2022 Mar 1. Epub 2022 Mar 1.

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina. Electronic address:

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Recurrent Eccrine Acrospiroma of the Parotid Region: A Case Report.

JNMA J Nepal Med Assoc 2021 Dec 11;59(244):1307-1309. Epub 2021 Dec 11.

Department of ENT- Head and Neck Surgery, All India Institute of Medical Sciences, Bhopal,462020, India.

Eccrine acrospiroma is a benign tumor of skin and adnexa arising from eccrine sweat gland epithelium. It is usually solitary, slow growing tumor commonly affecting extremities. Rarely it affects head and neck region, and extremely rare in parotid region. Read More

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December 2021

Cytomorphology of an uncommon cutaneous tumour.

Cytopathology 2022 May 5;33(3):412-414. Epub 2022 Mar 5.

Department of Pathology and Laboratory Medicine, All India Institute of Medical sciences, Bhubaneswar, India.

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Recent Advances on Immunohistochemistry and Molecular Biology for the Diagnosis of Adnexal Sweat Gland Tumors.

Cancers (Basel) 2022 Jan 18;14(3). Epub 2022 Jan 18.

French Network of Rare Skin Cancers, CARADERM, France.

Cutaneous sweat gland tumors are a subset of adnexal neoplasms that derive or differentiate into the sweat apparatus. Their great diversity, rarity, and complex terminology make their pathological diagnosis challenging. Recent findings have revealed a wide spectrum of oncogenic drivers, several of which are of diagnostic interest for pathologists. Read More

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January 2022

Giant vascular eccrine spiradenoma; A rare entity with review of literature.

Indian J Pathol Microbiol 2022 Jan-Mar;65(1):233-235

Department of Pathology, Rajan Babu Institute of Pulmonary Medicine and Tuberculosis, Kingsway Camp, New Delhi, India.

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February 2022

Acquired nasolacrimal duct obstruction: clinical and histological findings of 275 cases.

BMC Ophthalmol 2022 Jan 5;22(1):12. Epub 2022 Jan 5.

Centre of Eye Diseases, Vilnius University Hospital Santaros Klinikos, Santariskiu 2, LT-08661, Vilnius, Lithuania.

Background: Acquired nasolacrimal duct obstruction is a blockage of the lacrimal outflow system usually caused by local nonspecific inflammation of the lacrimal sac and the nasolacrimal duct. However, cases exist where the primary nasolacrimal system obstruction is caused by malignancies. Our aim was to investigate lacrimal sac pathologies in patients with acquired nasolacrimal duct obstruction and compare their clinical manifestations. Read More

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January 2022

Giant vascular spiradenocylindroma of the scalp clinically mimicking a vascular tumor.

J Cutan Pathol 2022 Apr 16;49(4):369-372. Epub 2021 Nov 16.

Department of Pathology and Laboratory Medicine, Loma Linda University Medical Center, Loma Linda, California, USA.

We present a giant vascular spiradenocylindroma (GVSC) with a unique presentation. The diagnosis of GVSC can be clinically and radiologically elusive. The differential diagnosis includes angiolipoma, angiosarcoma, and glomus-tumor-like vascular lesions. Read More

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Cutaneous ultrasound: key diagnostic tool for the relapse of a single eccrine spiradenoma.

J Ultrasound 2021 Oct 12. Epub 2021 Oct 12.

Department of Dermatology, Clínica Universidad de Navarra, Madrid, Spain.

Eccrine spiradenoma is a rare, benign, adnexal skin tumor of the sweat gland. It is frequently solitary and presents as a small lesion in the dermal or the subcutaneous fat layer. Eccrine spiradenomas rarely progress to malignant transformation but they can relapse. Read More

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October 2021

Giant eccrine acrospiroma of the scalp.

J Cutan Aesthet Surg 2021 Apr-Jun;14(2):238-240

Department of General Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Eccrine acrospiroma is a benign skin tumor that arises from the ducts of sweat glands, presents as small solid or cystic lesions that rarely can undergo malignant transformation, and leads to a diagnostic dilemma. We report a 32-year-old woman who presented with a large pedunculated tumor of the scalp that was excised and histopathologically proven to be a giant eccrine acrospiroma. This case is being presented because of its infrequent occurrence and the unusual large size of the lesion on the scalp that has been not reported in the literature so far. Read More

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September 2021

Eccrine spiradenoma mimicking adenoid cystic carcinoma cytologically (Two case reports and literature review).

Diagn Cytopathol 2022 Jan 15;50(1):E6-E12. Epub 2021 Sep 15.

Department of Pathology, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, Turkey.

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January 2022


Georgian Med News 2021 Jun(315):7-9

3Clinica Goldman and Hospital Moinhos de Vento, Porto Alegre/ RS, Brazil.

Solid-cystic hidradenoma is a benign cutaneous tumor that is most commonly found in the head, neck, trunk, and upper extremity regions of patients in the middle to older aged groups. Presentation on lower extremities and in particular on the foot is uncommon. Nodular hidradenomas represent a dermatological pitfall, being difficult to differentiate from basal cell carcinoma and melanoma. Read More

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Cytology of a subcutaneous nodule on hand: A rare case.

Cytopathology 2022 03 27;33(2):273-275. Epub 2021 Jul 27.

Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

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A rare case of Hidradenoma of the lower lip.

Am J Otolaryngol 2021 Nov-Dec;42(6):103108. Epub 2021 Jun 15.

Division of Otolaryngology-Head and Neck Surgery, George Washington University School of Medicine & Health Sciences, Washington, DC, United States of America.

Hidradenoma are rare benign tumors with eccrine or apocrine differentiation that most often presents as a small, firm, solitary dermal nodule. At times, hidradenoma shows striking cytologic and histologic similarity to other neoplasms, including its malignant counterpart, hidradenocarcinoma. We present the first reported case of benign hidradenoma of the lower lip. Read More

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January 2022

Giant vascular eccrine spiradenoma: the first case in the scrotum and review of the literature author.

Diagn Pathol 2021 Apr 30;16(1):37. Epub 2021 Apr 30.

College of Stomatology, Chongqing Medical University, Songshi Bei Road 426, Yubei District, 401147, Chongqing, China.

Background: Giant vascular eccrine spiradenoma is a rare variant of eccrine spiradenoma. It is different from the eccrine spiradenoma in its larger size and greater degree of vascularity. It is often clinically confusedwith a vascular or malignant tumor. Read More

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Primary Biphasic Hepatic Sarcoma in DICER1 Syndrome.

Pediatr Dev Pathol 2021 Sep-Oct;24(5):484-488. Epub 2021 Apr 19.

Department of Pathology and Laboratory Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

DICER1 tumor predisposition syndrome is a rare genetic disorder that predisposes individuals to multiple benign and malignant neoplasms. The phenotype is vast and includes pleuropulmonary blastoma (PPB), thyroid nodules, cystic nephroma, Wilms tumor, ovarian Sertoli-Leydig cell tumor, and medulloepithelioma, among others. Herein, we describe a patient with a germline pathogenic variant presenting with two neoplasms that are not commonly encountered in the context of DICER1 syndrome. Read More

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December 2021

A rare case of malignant eccrine spiradenoma mimicking carcinosarcoma.

Indian J Pathol Microbiol 2021 Apr-Jun;64(2):398-401

Department of Surgery, M R Bangur Super Speciality Hospital, Kolkata, West Bengal, India.

Malignant eccrine spiradenoma is an extremely rare neoplasm of adnexal origin. It almost always originates from a preexisting long standing eccrine spiradenoma. We present a case of malignant eccrine spiradenoma arising from benign counterpart and having both carcinomatous and sarcomatous differentiation. Read More

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October 2021

Ultrasonographic features of eccrine spiradenoma: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25469

Department of Ultrasound, Hebei General Hospital, Shijiazhuang, Hebei, China.

Rationale: Eccrine spiradenoma (ES) is a rare benign skin adnexal tumor originating from eccrine sweat glands. The features of ES on ultrasonography (US) have received little attention. Therefore, we report the sonographic findings in a case of an ES that originated from the abdominal wall and discuss the previously reported cases. Read More

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Eccrine spiradenoma: a rare adnexal tumour with atypical presentation: A case report.

J Pak Med Assoc 2021 02;71(2(A)):553-555

Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

First described in 1934, eccrine spiradenoma (ES) is a rare, benign adnexal tumour arising from eccrine sweat glands. It commonly presents as a slow-growing nodule on the upper trunk, and head and neck region, mostly in the age bracket of 15-35 years, with no gender preference. While no established guidelines exist for optimal management of malignant ES, some therapies have been studied. Read More

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February 2021


An Bras Dermatol 2021 Mar-Apr;96(2):251-253. Epub 2021 Feb 5.

Department of Dermatological Surgery, Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta, Manaus, AM, Brazil.

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Eccrine Hidradenoma of the Nasal Vestibule: A Rare Clinical Entity.

Ear Nose Throat J 2021 Feb 15:145561321995018. Epub 2021 Feb 15.

Department of Otorhinolaryngology and Biomedical Research Institute, 220312Pusan National University School of Medicine, Pusan National University Hospital, Busan, Republic of Korea.

Eccrine hidradenoma is a relatively rare benign tumor of sweat gland origin but with possible malignant transformation. It usually consists of solitary, well-demarcated papules or nodules covered with normal skin. Common sites of involvement are the scalp, face, limbs, and anterior trunk. Read More

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February 2021

Hidradenocarcinoma: a rare but challenging diagnosis.

Clin Imaging 2021 Jul 2;75:138-142. Epub 2021 Feb 2.

Departments of Pathology (S.C.), Surgery (S.K., D.L.) and Radiology (J.A.M., A.K.), Icahn School of Medicine at Mount Sinai West Hospital, 1000 10th Avenue, New York, NY, 10019, United States of America.

Hidradenocarcinoma is a rare, aggressive cancer arising from sweat glands. Hidradenocarcinoma has no definitive histologic features compared to its benign hidradenoma, thereby posing a diagnostic challenge for clinicians and pathologists. This novel case report demonstrates specific MRI signs that suggested malignant degeneration of hidradenoma. Read More

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Multiple rubbery nodules on the scalp.

JAAD Case Rep 2021 Feb 5;8:80-82. Epub 2021 Jan 5.

DiSSal Section of Dermatology, San Martino Polyclinic Hospital IRCCS, University of Genoa, Genoa, Italy.

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February 2021

Malignant Eccrine Adenoma With Sarcomatous (Heterologous) Components: Report of a Rare Skin Adnexal Neoplasm With Literature Review.

Cureus 2020 Dec 30;12(12):e12390. Epub 2020 Dec 30.

Histopathology, Aga Khan University Hospital, Karachi, PAK.

Malignant eccrine spiradenoma (MES) is an exceedingly rare skin adnexal tumor that arises from pre-existing benign eccrine spiradenoma (BES). MES tumors show a wide spectrum of morphological features, posing a diagnostic challenge to the pathologist. Sarcomatous (heterologous) elements are seen in a few of these tumors, further complicating the morphological picture. Read More

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December 2020

Challenges in diagnosis and management of a spiradenocarcinoma: a comprehensive literature review.

ANZ J Surg 2021 10 1;91(10):1996-2001. Epub 2021 Feb 1.

Monash University Endocrine Surgery Unit, Alfred Hospital, Melbourne, Victoria, Australia.

Background: Spiradenocarcinoma is a rare skin adnexal neoplasm that may behave aggressively. It is often associated with a benign slow-growing spiradenoma that has undergone malignant transformation. Given the paucity of cases in the literature, there is a lack of consensus on treatment. Read More

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October 2021

Malignant Eccrine Spiradenoma of the External Auditory Canal: A Case Report and Literature Review.

Front Oncol 2020 5;10:574112. Epub 2021 Jan 5.

Department of Radiation Oncology, Yantai Yuhuangding Hospital, Yantai, China.

Spiradenocarcinoma, or malignant eccrine spiradenoma (MES), is a rare sweat gland tumor originating from eccrine sweat glands. To the best of our knowledge, only two cases of MES of the external auditory canal have been reported to date. Here, we report a third case of MES located in the external auditory canal. Read More

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January 2021

Exceptional response to anti-PD-1 treatment in a patient with metastatic cutaneous hidradenocarcinoma.

Eur J Cancer 2021 03 16;145:143-145. Epub 2021 Jan 16.

Department of Dermatology and Allergy, School of Medicine, German Cancer Consortium (DKTK), Technical University of Munich, Germany; Faculty of Medicine, Sigmund Freud University Vienna, Austria. Electronic address:

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Three Cases of Clear Cell Hidradenoma With "Benign" Lymph Node Involvement.

Am J Dermatopathol 2021 Jun;43(6):e76-e79

Department of Pathology, Hospital Universitario Doce de Octubre, Universidad Complutense, Instituto de Investigación I+12, Madrid, Spain; and.

Abstract: The malignant counterpart of cutaneous clear cell hidradenoma (CCH), hidradenocarcinoma, is an aggressive neoplasm that may have a fatal outcome. However, some cases of benign looking CCH with isolated lymph node involvement and excellent prognosis have been described. "CCH-like neoplasm of uncertain malignant potential" or "atypical hidradenoma" have been proposed as designations for these lesions. Read More

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