21,198 results match your criteria Spine[Journal]


Lumbar laminotomy for the intrathecal administration of nusinersen for spinal muscular atrophy: technical note and outcomes.

J Neurosurg Spine 2019 Apr 19:1-5. Epub 2019 Apr 19.

3Neurological Surgery, Oregon Health & Science University, Portland, Oregon.

Nusinersen (Spinraza) is a US Food and Drug Administration-approved intrathecal medication for the treatment of spinal muscular atrophy (SMA). Adult patients with SMA often undergo thoracolumbar fusion to treat neurogenic scoliosis, preventing thecal access. The authors report a laminotomy technique and the ease of intrathecal access in three SMA patients with prior thoracolumbar fusions. Read More

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https://thejns.org/view/journals/j-neurosurg-spine/aop/artic
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http://dx.doi.org/10.3171/2019.2.SPINE181366DOI Listing
April 2019
1 Read

Adjacent-segment disease following two-level axial lumbar interbody fusion.

J Neurosurg Spine 2019 Apr 19:1-8. Epub 2019 Apr 19.

3Department of Orthopaedic Surgery, University of Tennessee College of Medicine, Chattanooga, Tennessee.

OBJECTIVEWhile long-term studies have evaluated adjacent-segment disease (ASD) following posterior lumbar spine arthrodesis, no such studies have assessed the incidence and prevalence of ASD following axial lumbar interbody fusion (AxiaLIF). The aim of this study was to estimate the incidence of ASD following AxiaLIF.METHODSThe authors retrospectively reviewed the medical records of 149 patients who underwent two-level index AxiaLIF and had at least 2 years of radiographic and clinical follow-up. Read More

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https://thejns.org/view/journals/j-neurosurg-spine/aop/artic
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http://dx.doi.org/10.3171/2019.2.SPINE18929DOI Listing
April 2019
1 Read

Arachnoid web of the spine: a systematic literature review.

J Neurosurg Spine 2019 Apr 19:1-10. Epub 2019 Apr 19.

2Department of Neurosurgery, Weill Cornell Brain and Spine Center, New York, New York.

OBJECTIVEAn arachnoid web of the spine (AWS) is a rare and oftentimes challenging lesion to diagnose, given its subtle radiographic findings. However, when left untreated, this lesion can have devastating effects on a patient's neurological function. To date, only limited case reports and series have been published on this topic. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE181371DOI Listing
April 2019
1 Read

Understanding quality of life and treatment history of patients with Bertolotti syndrome compared with lumbosacral radiculopathy.

J Neurosurg Spine 2019 Apr 19:1-7. Epub 2019 Apr 19.

4Center for Spine Health, Department of Neurosurgery, Neurologic Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

OBJECTIVEBertolotti syndrome is a rare spinal condition that causes low-back pain due to a lumbosacral transitional vertebra (LSTV), which is a pseudoarticulation between the fifth lumbar transverse process and the sacral ala. Bertolotti syndrome patients are rarely studied, particularly with regard to their quality of life. This study aimed to examine the quality of life and prior treatments in patients with Bertolotti syndrome at first presentation to the authors' center in comparison with those with lumbosacral radiculopathy. Read More

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http://dx.doi.org/10.3171/2019.2.SPINE1953DOI Listing

Validation of a freehand technique for cortical bone trajectory screws in the lumbar spine.

J Neurosurg Spine 2019 Apr 19:1-8. Epub 2019 Apr 19.

1Division of Orthopaedic Surgery, University of Toronto, Toronto.

OBJECTIVEThe cortical bone trajectory (CBT) technique for pedicle screw placement has gained popularity among spinal surgeons. It has been shown biomechanically to provide better fixation and improved pullout strength compared to a traditional pedicle screw trajectory. The CBT technique also allows for a less invasive approach for fusion and may have lower incidence of adjacent-level disease. Read More

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https://thejns.org/view/journals/j-neurosurg-spine/aop/artic
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http://dx.doi.org/10.3171/2019.1.SPINE181402DOI Listing
April 2019
1 Read

The 5-Item modified frailty index is predictive of severe adverse events in patients undergoing surgery for adult spinal deformity.

Spine (Phila Pa 1976) 2019 Mar 29. Epub 2019 Mar 29.

Department of Orthopedic Surgery, Keio University School of Medicine.

Study Design: A retrospective review of 281 consecutive cases of adult spine deformity (ASD) surgery (age 55 ± 19 years, 91% female, follow-up 4.3 ± 1.9 years) from a multicenter database. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003063DOI Listing
March 2019
1 Read

Genetic Variants of ABO and SOX6 are Associated with Adolescent Idiopathic Scoliosis in Chinese Han Population.

Spine (Phila Pa 1976) 2019 Mar 29. Epub 2019 Mar 29.

Department of Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

Study Design: A genetic association study.

Objective: The aim of this study was to determine whether variants of ABO, SOX6, and CDH13 are associated with the susceptibility of AIS in Chinese Han population.

Summary Of Background Data: A recent large-scale genome-wide association study reported three novel loci in CDH13, ABO, and SOX6 genes associated with adolescent idiopathic scoliosis (AIS) in Japanese population. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003062DOI Listing

Mechanical Performance of Posterior Spinal Instrumentation and Growing Rod Implants: Experimental and Computational Study.

Spine (Phila Pa 1976) 2019 Mar 29. Epub 2019 Mar 29.

Department of Orthopaedic Surgery, Medical School, University of Minnesota, Minneapolis, Minnesota.

MINI: This study compared mechanical performance of posterior spinal instrumentation and growing rods instrumentation using vertebrectomy model methodology. Growing rods were stiffer and stronger. Mechanical was within 10% of computational simulations for both models with 76 mm active lengths. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003061DOI Listing
March 2019
1 Read

Comparison of Short-term Outcomes After Lumbar Fusion Between an Orthopedic Specialty Hospital and Tertiary Referral Center.

Spine (Phila Pa 1976) 2019 May;44(9):652-658

Department of Orthopaedic Surgery, Rothman Institute at Thomas Jefferson University, Philadelphia, PA.

Study Design: A retrospective review of all elective single-level lumbar fusions performed at a single orthopedic specialty hospital (OSH) and tertiary referral center (TRC).

Objective: This study compared the perioperative outcomes for lumbar fusion procedures performed at an OSH and TRC.

Summary Of Background Data: The role of an OSH for lumbar fusion procedures has not been defined. Read More

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http://dx.doi.org/10.1097/BRS.0000000000002911DOI Listing

"The Pena Palace in the Sintra Mountains in Portugal".

Authors:

Spine (Phila Pa 1976) 2019 May;44(9)

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http://dx.doi.org/10.1097/01.brs.0000557842.26739.48DOI Listing

Risk and Prognostic Factors of Low Back Pain: Repeated Population Based Cohort Study in Sweden.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Finnish Institute of Occupational Health, Helsinki, Finland.

Study Design: Prospective longitudinal cohort study.

Objective: To determine the associations ofr workload and health-related factors with incident and recurrent low back pain (LBP), and to determine the mediating role of health-related factors in associations between physical workload factors and incident LBP.

Summary Of Background Data: It is not known whether the risk factors for the development of LBP are also prognostic factors for recurrence of LBP and whether the associations between physical workload and incident LBP are mediated by health-related factors. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003052DOI Listing
March 2019
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Modic Changes are not Associated with Long-Term Pain and Disability - A Cohort Study With 13-Year Follow-up.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Spine Surgery and Research, Spine Center of Southern Denmark - part of Lillebaelt Hospital.

Study Design: A comparative cohort study with 13-year follow-up.

Objective: To assess whether Modic Changes (MCs) are associated with long-term physical disability, back pain and sick leave.

Summary Of Background Data: Previous studies have shown a conflicting association of low back pain (LBP) with MCs and disc degeneration. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003051DOI Listing

The Association Between Patient Reported Outcomes of Spinal Surgery and Societal Costs: A Register Based Study.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Quantify Research, Stockholm, Sweden.

Study Design: Retrospective register-based study using Swedish registers and data prospectively collected in quality register Swespine.

Objective: Analyse the association of societal costs and spine surgery outcome in low back pain (LBP) patients based on patient reported outcome measures (PROMs).

Summary Of Background Data: Studies show that LBP has a substantial impact on societal cost. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003050DOI Listing
March 2019
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Magnetically Controlled Growing Rods in Treatment of Early-Onset Scoliosis: A Single Center Study with a Minimum of 2-Year-Follow up and Preliminary Results After Converting Surgery.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Department of Orthopedics and Tumor Orthopedics, Muenster University Hospital.

Study Design: Case series OBJECTIVE.: To evaluate complications and radiographic parameters after Magnetically Controlled Growing Rod (MCGR) index surgery (IS), during lengthening and following converting surgery (CS) with a minimum of 2-year follow up (FU).

Summary Of Background Data: MCGR are maintaining skeletal growth in treatment of early onset scoliosis (EOS). Read More

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http://dx.doi.org/10.1097/BRS.0000000000003048DOI Listing

Blood Loss of Posterior Lumbar Interbody Fusion on Lumbar Stenosis in Patients with Rheumatoid Arthritis: A Case-Control Study.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Department of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, P.R. China.

Study Design: .: Case-control study OBJECTIVE.: To compare intraoperative bleeding, drainage and hidden blood loss (HBL) of posterior lumbar interbody fusion (PLIF) on lumbar spinal stenosis (LSS) in patients with rheumatoid arthritis (RA) and non-RA and identify the risk factors of HBLwith RA. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003037DOI Listing
March 2019
2 Reads

Post-Traumatic Stress Disorder Symptoms are Associated with Incident Chronic Back Pain: A Longitudinal Twin Study of Older Male Veterans.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Seattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, USA.

Study Design: Longitudinal co-twin control study of the Vietnam-Era Twin Registry.

Objective: To examine the association of post-traumatic stress disorder (PTSD) symptoms with incident chronic back pain (CBP), while controlling for genetic factors and early family environment.

Summary Of Background Data: It is unknown whether PTSD symptoms are associated with an increased incidence of CBP. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003053DOI Listing
March 2019
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Normalization of Spinal Cord Displacement with the Straight leg Raise and Resolution of Sciatica in Patients with Lumbar Intervertebral Disc Herniation: A 1.5-Year Follow-up Study.

Spine (Phila Pa 1976) 2019 Mar 26. Epub 2019 Mar 26.

Department of Physical and Rehabilitation Medicine, Kuopio University Hospital, Kuopio.

Study Design: Controlled radiologic follow-up study.

Objective: To ascertain if changes in cord excursion with SLR at 1.5-year follow-up time accompany changes in clinical symptoms SUMMARY OF BACKGROUND DATA. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003047DOI Listing
March 2019
1 Read

Double-blind, randomized controlled trial of tranexamic acid in minor lumbar spine surgery: no effect on operative time, intraoperative blood loss, or complications.

J Neurosurg Spine 2019 Apr 12:1-7. Epub 2019 Apr 12.

OBJECTIVEThe purpose of this study was to investigate the effect of tranexamic acid (TXA) compared to placebo in low-risk adult patients undergoing elective minor lumbar spine surgery-specifically with respect to operative time, estimated blood loss, and complications. Studies have shown that TXA reduces blood loss during major spine surgery. There have been no previous studies on the effect of TXA in minor lumbar spine surgery in which these variables have been evaluated. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE1814DOI Listing
April 2019
1 Read

Tailoring selection of transforaminal interbody spacers based on biomechanical characteristics and surgical goals: evaluation of an expandable spacer.

J Neurosurg Spine 2019 Apr 12:1-7. Epub 2019 Apr 12.

1Department of Neurosurgery and.

OBJECTIVETransforaminal lumbar interbody fusion (TLIF) is commonly used for lumbar fusion, such as for foraminal decompression, stabilization, and improving segmental lordosis. Although many options exist, surgical success is contingent on matching design strengths with surgical goals. The goal in the present study was to investigate the effects of an expandable interbody spacer and 2 traditional static spacer designs in terms of stability, compressive stiffness, foraminal height, and segmental lordosis. Read More

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https://thejns.org/view/journals/j-neurosurg-spine/aop/artic
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http://dx.doi.org/10.3171/2019.1.SPINE181008DOI Listing
April 2019
1 Read

Compressive Pressure versus Time in Cauda Equina Syndrome: A Systematic Review and Meta-Analysis of Experimental Studies.

Spine (Phila Pa 1976) 2019 Apr 8. Epub 2019 Apr 8.

Department of Clinical Neuroscience, Western General Hospital, Edinburgh.

Study Design: Systematic review and meta-analysis OBJECTIVE.: To examine the relationship between compressive pressure and its duration in cauda equina compression, and the effects subsequent decompression, on neurophysiological function and pathophysiology in animal studies. We further aim to investigate these relationships with systemic blood pressure to assess whether a vascular component in the underlying mechanism may contribute to the clinical heterogeneity of this disease. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003045DOI Listing
April 2019
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The Role of Type I Diabetes in Intervertebral Disc Degeneration.

Spine (Phila Pa 1976) 2019 Apr 8. Epub 2019 Apr 8.

Ferguson Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Study Design: An experimental laboratory study.

Objective: To investigate the pathogenesis of intervertebral disc degeneration (IDD) in a murine model of type 1 diabetes mellitus (DM), namely non-obese diabetic (NOD) mouse.

Summary Of Background Data: IDD is a leading contributor of low back pain, which represents one of the most disabling symptoms within the adult population. Read More

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http://Insights.ovid.com/crossref?an=00007632-900000000-9468
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http://dx.doi.org/10.1097/BRS.0000000000003054DOI Listing
April 2019
2 Reads
2.297 Impact Factor

Predictive Factors of Male Sexual Dysfunction after Traumatic Spinal Cord Injury.

Spine (Phila Pa 1976) 2019 Apr 8. Epub 2019 Apr 8.

Department of Physical Therapy, Health Sciences Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.

Study Design: Observational study (Ethics Committee Number 973.648).

Objective: Evaluating the social and clinical factors associated with sexual dysfunction in men with traumatic spinal cord injury, as well as predictive factors for sexual dysfunction. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003049DOI Listing
April 2019
2 Reads

Short-term Outcomes Following Cervical Laminoplasty and Decompression and Fusion with Instrumentation.

Spine (Phila Pa 1976) 2019 Apr 8. Epub 2019 Apr 8.

Division of Spinal Surgery/Departments of Orthopaedic and Neurosurgery, NYU Medical Center, NY Spine Institute, New York, NY, USA.

Study Design: Retrospective review of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database years 2010-2015.

Objective: Investigate which short-term outcomes differ for cervical laminoplasty and laminectomy and fusion surgeries.

Summary Of Background Data: Conflicting reports exist in spine literature regarding short-term outcomes following cervical laminoplasty and posterior laminectomy and fusion. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003057DOI Listing
April 2019
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Patient Factors Affecting Emergency Department Utilization and Hospital Readmission Rates after Primary Anterior Cervical Discectomy and Fusion: A review of 41,813 cases.

Spine (Phila Pa 1976) 2019 Apr 8. Epub 2019 Apr 8.

All authors are affiliated with the Hospital for Special Surgery.

Study Design: Retrospective database analysis.

Objective: To identify preoperative risk factors for ED visit and unplanned hospital readmission after primary ACDF at 30 and 90 days.

Summary Of Background Data: Limited data exist to identify factors associated with ED visit or readmission after primary anterior cervical discectomy and fusion (ACDF) within the first 3 months following surgery. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003058DOI Listing
April 2019
1 Read

The Long-Term Reoperation Rate Following Surgery for Lumbar Herniated Intervertebral Disc Disease: A Nationwide Sample Cohort Study with A 10-Year Follow-Up.

Spine (Phila Pa 1976) 2019 Apr 5. Epub 2019 Apr 5.

Department of Neurosurgery, Seoul National University Hospital, Seoul, South Korea.

MINI: The reoperation probabilities for lumbar herniated intervertebral disc disease did not differ among open discectomy, laminectomy, percutaneous endoscopic discectomy and fusion during the 10-year follow-up period. However, OD was the most commonly used technique in reoperation.

Study Design: Retrospective cohort study of a nationwide sample database. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003065DOI Listing
April 2019
3 Reads
2.297 Impact Factor

Preoperative Chronic Opioid Therapy Negatively Impacts Long Term Outcomes Following Cervical Fusion Surgery.

Spine (Phila Pa 1976) 2019 Apr 5. Epub 2019 Apr 5.

Spine Surgery, Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA 52242.

MINI: The study investigates the association between preoperative chronic opioid therapy on long-term outcomes (reoperations, ED visits, postoperative opioid use, and adverse events)in patients undergoing primary cervical spine arthrodesis using a commercial claims dataset.

Study Design: Retrospective, observational.

Objective: To define the impact of preoperative chronic opioid therapy (COT) on outcomes following cervical spine fusions. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003064DOI Listing
April 2019
2 Reads

Sex Differences in Rat Intervertebral Disc Structure and Function Following Annular Puncture Injury.

Spine (Phila Pa 1976) 2019 Apr 5. Epub 2019 Apr 5.

Department of Orthopaedics, Icahn School of Medicine at Mount Sinai, New York, NY.

Study Design: A rat puncture injury intervertebral disc (IVD) degeneration model with structural, biomechanical, and histological analyses.

Objective: To determine if males and females have distinct responses in the IVD after injury.

Summary Of Background Data: Low back pain (LBP) and spinal impairments are more common in women than men. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003055DOI Listing
April 2019
2 Reads

Need for arthrodesis following facetectomy for spinal peripheral nerve sheath tumors: an institutional experience and review of the current literature.

J Neurosurg Spine 2019 04 5:1-11. Epub 2019 Apr 5.

Mayo Clinic Neuro-Informatics Laboratory, and

Objective: Spinal peripheral nerve sheath tumors (PNSTs) are a group of rare tumors originating from the nerve and its supporting structures. Standard surgical management typically entails laminectomy with or without facetectomy to gain adequate tumor exposure. Arthrodesis is occasionally performed to maintain spinal stability and mitigate the risk of postoperative deformity, pain, or neurological deficit. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE181057DOI Listing
April 2019
1 Read

Comparative study of multilevel posterior interbody fusion plus anterior longitudinal ligament release versus classic multilevel posterior interbody fusion in the treatment of adult spinal deformities.

J Neurosurg Spine 2019 04 5:1-7. Epub 2019 Apr 5.

Objective: Sagittal imbalance and loss of lumbar lordosis are the main drivers of functional disability in adult degenerative scoliosis. The main limitations of the classic posterior lumbar interbody fusion technique are increased risk of neurological injury and suboptimal correction of the segmental lordosis. Here, the authors describe the radiological results of a modified posterior lumbar interbody fusion and compare the results with a historical cohort of patients. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE18754DOI Listing
April 2019
4 Reads

What is the treatment effect of surgery compared with nonoperative treatment in patients with lumbar spinal stenosis at 1-year follow-up?

J Neurosurg Spine 2019 04 5:1-9. Epub 2019 Apr 5.

Horten Centre for Patient Oriented Research and Knowledge Transfer, University of Zurich.

Objective: The aim of this study was to obtain an unbiased causal treatment estimate of the between-group difference of surgery versus nonoperative treatment with respect to outcomes on quality of life, pain, and disability in patients with degenerative lumbar spinal stenosis (DLSS) 12 months after baseline.

Methods: The authors included DLSS patients from a large prospective multicenter observational cohort study. Propensity score matching was used, including 15 demographic, clinical, and MRI variables. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE181098DOI Listing
April 2019
2 Reads

Do untreated intraspinal anomalies in congenital scoliosis impact the safety and efficacy of spinal correction surgery? A retrospective case-control study.

J Neurosurg Spine 2019 04 5:1-6. Epub 2019 Apr 5.

Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

Objective: Intraspinal anomalies associated with congenital scoliosis (CS) complicate the decision-making process for spinal correction surgery in CS patients. Recently, deformity correction surgery without prior prophylactic neurological intervention has been recognized to be safe in CS patients with intact or stable neurological status. However, no case-control study has identified the surgical outcomes and risks of spinal correction surgery in this patient population. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE181205DOI Listing
April 2019
3 Reads

Spinal trauma in Tanzania: current management and outcomes.

J Neurosurg Spine 2019 04 5:1-9. Epub 2019 Apr 5.

Departments of1Neurological Surgery and.

Objective: Spinal trauma is a major cause of disability worldwide. The burden is especially severe in low-income countries, where hospital infrastructure is poor, resources are limited, and the volume of cases is high. Currently, there are no reliable data available on incidence, management, and outcomes of spinal trauma in East Africa. Read More

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http://dx.doi.org/10.3171/2018.12.SPINE18635DOI Listing
April 2019
2 Reads

Reconstruction of the spinal accessory nerve with selective fascicular nerve transfer of the upper trunk.

J Neurosurg Spine 2019 04 5:1-6. Epub 2019 Apr 5.

1Christian Doppler Laboratory for Restoration of Extremity Function, Department of Surgery, Medical University of Vienna.

Objective: Spinal accessory nerve palsy is frequently caused by iatrogenic damage during neck surgery in the posterior triangle of the neck. Due to late presentation, treatment regularly necessitates nerve grafts, which often results in a poor outcome of trapezius function due to long regeneration distances. Here, the authors report a distal nerve transfer using fascicles of the upper trunk related to axillary nerve function for reinnervation of the trapezius muscle. Read More

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http://dx.doi.org/10.3171/2018.12.SPINE18498DOI Listing
April 2019
4 Reads

Surgical approaches and long-term outcomes of intramedullary spinal cord cavernous malformations: a single-center consecutive series of 219 patients.

J Neurosurg Spine 2019 04 5:1-10. Epub 2019 Apr 5.

Objective: Optimal surgical strategies for intramedullary spinal cord cavernous malformations (ISCCMs) are not optimized and remain problematic. In this study the authors identify rational surgical strategies for ISCCMs and predictors of outcomes after resection.

Methods: A single-center study was performed with 219 consecutive surgically treated patients who presented from 2002 to 2017 and were analyzed retrospectively. Read More

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http://dx.doi.org/10.3171/2018.12.SPINE181263DOI Listing
April 2019
1 Read

Geography of Lumbar Paravertebral Muscle Fatty Infiltration: The Influence of Demographics, Low Back Pain, and Disability.

Spine (Phila Pa 1976) 2019 Apr 2. Epub 2019 Apr 2.

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.

Study Design: Cross-sectional OBJECTIVE.: We quantified fatty infiltration (FI) geography of the lumbar spine to identify whether demographics, temporal low back pain (LBP), and disability influence FI patterns.

Summary Of Background Data: Lumbar paravertebral muscle FI has been associated with age, sex, LBP, and disability; yet, FI accumulation patterns are inadequately described to optimise interventions. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003060DOI Listing
April 2019
3 Reads

Paraoxonase 1 (PON1) was Negatively Associated with Intervertebral Disc Degeneration (IVDD).

Spine (Phila Pa 1976) 2019 Apr 2. Epub 2019 Apr 2.

Department of Spine Surgery, the First Affiliated Hospital and Orthopedic Research Institute of Sun Yat-sen University, No.58 Zhongshan Er Road, Guangzhou, China, 510080.

MINI: Paraoxonase 1 (PON1) is an enzyme with anti-inflammatory and anti-oxidative effects. Expression of PON1 is suppressed in degenerated discs and degenerative NP cell models. Knockdown of PON1 showed increased inflammatory and oxidative stress levels and decreased extracellular matrix levels in NP cells. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003059DOI Listing
April 2019
4 Reads
2.297 Impact Factor

Anterior Atlantooccipital Transarticular Screw Fixation: A Cadaveric Study and Description of a Novel Technique.

Spine (Phila Pa 1976) 2019 Apr 2. Epub 2019 Apr 2.

Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.

MINI: By measurements on the CT slices of 30 patients and operation on eight cadaver specimens, the ideal anterior atlantooccipital screw directed 41.7° posteriorly in the sagittal plane and 11.6° laterally in the coronal plane, with a safe length around 30. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003056DOI Listing
April 2019
3 Reads

The evolution of surgical management for vertebral column tumors.

J Neurosurg Spine 2019 Apr;30(4):417-423

In BriefThere has been a significant shift in treatment paradigms for both primary and metastatic spine tumors over the last several decades. This article highlights some of the more important treatment advances that practitioners should be made aware of. It is important to not only incorporate these changes into individual practice but also appreciate the treatment trends that herald a significantly different future for spine tumor treatment. Read More

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http://dx.doi.org/10.3171/2018.12.SPINE18708DOI Listing
April 2019
2 Reads

Extended L5 pedicle subtraction osteotomy for neglected sacropelvic dissociation injury: case report.

J Neurosurg Spine 2019 Mar 29:1-5. Epub 2019 Mar 29.

2Swedish Neurosciences Institute, Seattle, Washington.

The sacrum forms the distal end of the spine and communicates with the pelvis. Fractures involving the sacrum are complex and may disrupt this vital communication. Neglecting these fractures may result in malunion, which often causes significant alteration in the pelvic parameters and sagittal balance. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE181271DOI Listing

Outpatient and inpatient readmission rates of 3- and 4-level anterior cervical discectomy and fusion surgeries.

J Neurosurg Spine 2019 03 29:1-6. Epub 2019 Mar 29.

2Chicago Medical School, North Chicago, Illinois.

OBJECTIVE With the costs related to the United States medical system constantly rising, efforts are being made to turn traditional inpatient procedures into outpatient same-day surgeries. In this study the authors looked at the various comorbidities and perioperative complications and their impact on readmission rates of patients undergoing outpatient versus inpatient 3- and 4-level anterior cervical discectomy and fusion (ACDF). METHODS This was a retrospective study of 337 3- and 4- level ACDF procedures in 332 patients (5 patients had both primary and revision surgeries that were included in this total of 337 procedures) between May 2012 and June 2017. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE181019DOI Listing
March 2019
1 Read

Investigating the utility of intraoperative neurophysiological monitoring for anterior cervical discectomy and fusion: analysis of over 140,000 cases from the National (Nationwide) Inpatient Sample data set.

J Neurosurg Spine 2019 03 29:1-11. Epub 2019 Mar 29.

1Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario; and.

OBJECTIVE Intraoperative neurophysiological monitoring (IONM) is a useful adjunct in spine surgery, with proven benefit in scoliosis-correction surgery. However, its utility for anterior cervical discectomy and fusion (ACDF) is unclear, as there are few head-to-head comparisons of ACDF outcomes with and without the use of IONM. The authors sought to evaluate the impact of IONM on the safety and cost of ACDF. Read More

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http://dx.doi.org/10.3171/2019.1.SPINE181110DOI Listing

Spine trauma and spinal cord injury in Utah: a geographic cohort study utilizing the National Inpatient Sample.

J Neurosurg Spine 2019 03 29:1-10. Epub 2019 Mar 29.

OBJECTIVE The objective of this study was to investigate the effect of hospital type and patient transfer during the treatment of patients with vertebral fracture and/or spinal cord injury (SCI). METHODS The National Inpatient Sample (NIS) database was queried to identify patients treated in Utah from 2001 to 2011 for vertebral column fracture and/or SCI (ICD-9-CM codes 805, 806, and 952). Variables related to patient transfer into and out of the index hospital were evaluated in relation to patient disposition, hospital length of stay, mortality, and cost. Read More

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http://dx.doi.org/10.3171/2018.12.SPINE18964DOI Listing

Augmented reality-assisted pedicle screw insertion: a cadaveric proof-of-concept study.

J Neurosurg Spine 2019 03 29:1-8. Epub 2019 Mar 29.

Departments of1Neurosurgery and.

OBJECTIVE Augmented reality (AR) is a novel technology that has the potential to increase the technical feasibility, accuracy, and safety of conventional manual and robotic computer-navigated pedicle insertion methods. Visual data are directly projected to the operator’s retina and overlaid onto the surgical field, thereby removing the requirement to shift attention to a remote display. The objective of this study was to assess the comparative accuracy of AR-assisted pedicle screw insertion in comparison to conventional pedicle screw insertion methods. Read More

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http://dx.doi.org/10.3171/2018.12.SPINE181142DOI Listing

Effect of Serious Adverse Events on Health-Related Quality of Life Measures Following Surgery for Adult Symptomatic Lumbar Scoliosis.

Spine (Phila Pa 1976) 2019 Mar 20. Epub 2019 Mar 20.

Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO.

Study Design: Secondary analysis of prospective multicenter cohort OBJECTIVE.: To assess effect of serious adverse events (SAEs) on 2- and 4-year patient-reported outcomes measures (PROMs) in patients surgically treated for adult symptomatic lumbar scoliosis (ASLS) SUMMARY OF BACKGROUND DATA.: Operative treatment for ASLS can improve health-related quality of life (HRQL), but has high rates of SAEs. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003036DOI Listing

Sacropelvic fixation with S2 alar iliac screws may prevent sacroiliac joint pain after multi-segment spinal fusion.

Spine (Phila Pa 1976) 2019 Mar 20. Epub 2019 Mar 20.

Department of Orthopedic Surgery, Akita University Graduate School of Medicine, Akita, Japan.

Study Design: A retrospective study OBJECTIVE.: To examine the postoperative incidence of sacroiliac joint pain (SIJP) at the lower fusion level following multi-segment fusion.

Summary Of Background Data: Recently, multi-segment fusion is being increasingly performed. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003041DOI Listing

Disaster Scenarios in Spine Surgery. A Survey Analysis.

Spine (Phila Pa 1976) 2019 Mar 20. Epub 2019 Mar 20.

Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, United States.

MINI: A survey was created including five hypothetical unpredicted scenarios affecting different organ systems to assess the respondents' preferred reactions. The heterogeneity of responses in the face of "disaster scenario" intraoperative events shows there is room for more thorough and directed education of spine surgeons during training.

Study Design: Survey analysis among spine surgeons OBJECTIVE. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003040DOI Listing
March 2019
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2019 ISSLS Wiltse Lifetime Achievement Award.

Authors:
Shinichi Kikuchi

Spine (Phila Pa 1976) 2019 Mar 20. Epub 2019 Mar 20.

Fukushima Medical University, School of Medicine.

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http://dx.doi.org/10.1097/BRS.0000000000003038DOI Listing

Endothelin-1 Activates the Notch Signaling Pathway and Promotes Tumorigenesis in Giant Cell Tumor of the Spine.

Spine (Phila Pa 1976) 2019 Mar 20. Epub 2019 Mar 20.

Department of Orthopaedic Oncology, Spinal Tumor Center, Changzheng Hospital, Navy Military Medical University, Shanghai, 200003, China.

Study Design: .: Experimental study.

Objective: . Read More

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http://dx.doi.org/10.1097/BRS.0000000000003044DOI Listing

Pedicle Stress Injury in Children and Adolescents with Low Back Pain.

Spine (Phila Pa 1976) 2019 Mar 20. Epub 2019 Mar 20.

Health Science University, Department of Radiology, GOP Taksim Training and Research Hospital, İstanbul.

Study Design: A cross-sectional, retrospective cohort study.

Objective: To examine the prevalence of the pedicle stress injury, spondylolysis in children and adolescents with low back pain. And secondly, to test the hypothesis that these pathologies are associated with lumbar lordosis angle. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003046DOI Listing
March 2019
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